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Wyszukujesz frazę ""DNA methylation"" wg kryterium: Temat


Tytuł :
Identification of functional methylated CpG loci in PD-L1 promoter as the novel epigenetic biomarkers for primary gastric cancer.
Autorzy :
Amini M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hejazi M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ghorban K; Department of Immunology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran.
Mokhtarzadeh A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Baradaran B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
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Źródło :
Gene [Gene] 2021 Mar 10; Vol. 772, pp. 145376. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
B7-H1 Antigen/*genetics
Biomarkers, Tumor/*genetics
Stomach Neoplasms/*diagnosis
Cohort Studies ; CpG Islands ; Down-Regulation ; Early Detection of Cancer ; Epigenesis, Genetic ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Neoplasm Grading ; Promoter Regions, Genetic ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology ; Survival Analysis
Czasopismo naukowe
Tytuł :
DNA methylation changes stimulated by drought stress in ABA-deficient maize mutant vp10.
Autorzy :
Sallam N; Department of Genetics, Faculty of Agriculture, Alexandria University, Alexandria, 21545, Egypt. Electronic address: .
Moussa M; Department of Genetics, Faculty of Agriculture, Alexandria University, Alexandria, 21545, Egypt.
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Źródło :
Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Mar; Vol. 160, pp. 218-224. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Abscisic Acid*
Arabidopsis*/genetics
DNA Methylation*
Droughts*
Stress, Physiological*
Zea mays/*genetics
Epigenesis, Genetic ; Gene Expression Regulation, Plant ; Zea mays/metabolism
Czasopismo naukowe
Tytuł :
Detecting differentially methylated regions using a fast wavelet-based approach to functional association analysis.
Autorzy :
Denault WRP; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway. .; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. .; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. .
Jugessur A; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway.; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Feb 10; Vol. 22 (1), pp. 61. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Quantitative Trait Loci*
Bayes Theorem ; Computer Simulation ; Phenotype
Czasopismo naukowe
Tytuł :
Identification of DNA (de)methylation-related genes and their transcriptional response to environmental challenges in an invasive model ascidian.
Autorzy :
Fu R; Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China.
Huang X; Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Zhan A; Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 05; Vol. 768, pp. 145331. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
DNA (Cytosine-5-)-Methyltransferase 1/*metabolism
DNA (Cytosine-5-)-Methyltransferases/*metabolism
DNA-Binding Proteins/*metabolism
Urochordata/*physiology
Animals ; Cloning, Molecular ; DNA (Cytosine-5-)-Methyltransferase 1/genetics ; DNA (Cytosine-5-)-Methyltransferases/genetics ; DNA-Binding Proteins/genetics ; Databases, Protein ; Epigenesis, Genetic ; Introduced Species ; Methyl-CpG-Binding Protein 2/genetics ; Methyl-CpG-Binding Protein 2/metabolism ; Phylogeny ; Promoter Regions, Genetic ; Salt Stress ; Time Factors ; Urochordata/genetics
Czasopismo naukowe
Tytuł :
VHL gene methylation contributes to excessive erythrocytosis in chronic mountain sickness rat model by upregulating the HIF-2α/EPO pathway.
Autorzy :
Yang M; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China.
Zhu M; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China; Affiliated Hospital of Qinghai University, Xining 810001, China.
Song K; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China; Qinghai Provincial People's Hospital, Xining 810001, China.
Wuren T; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China.
Yan J; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China.
Ge RL; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China.
Ji L; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China; Huadu District People's Hospital of Guangzhou, Guangzhou 510800, China. Electronic address: .
Cui S; Research Center for High Altitude Medicine, Qinghai University, Xining 810001, China; Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province, Xining 810001, China; Affiliated Hospital of Qinghai University, Xining 810001, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Feb 01; Vol. 266, pp. 118873. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Altitude Sickness/*physiopathology
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Erythropoietin/*metabolism
Hypoxia/*physiopathology
Polycythemia/*pathology
Von Hippel-Lindau Tumor Suppressor Protein/*metabolism
Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Chronic Disease ; Disease Models, Animal ; Erythropoietin/genetics ; Gene Expression Regulation ; Male ; Polycythemia/genetics ; Polycythemia/metabolism ; Rats ; Rats, Sprague-Dawley ; Von Hippel-Lindau Tumor Suppressor Protein/genetics
Czasopismo naukowe
Tytuł :
Effect of Uhrf1 on intestinal development.
Autorzy :
Wang XY; School of Medicine, Anhui University of Science and Technology, Huainan 232000, China.; Department of Gastroenterology, South Campus of Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201499, China.
Li L; School of Life Sciences, East China Normal University, Shanghai Key Laboratory of Regulatory Biology, Shanghai 200241, China.; Department of Gastroenterology, South Campus of Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201499, China.
Duan QH; School of Life Sciences, East China Normal University, Shanghai Key Laboratory of Regulatory Biology, Shanghai 200241, China.
Li DL; School of Life Sciences, East China Normal University, Shanghai Key Laboratory of Regulatory Biology, Shanghai 200241, China.
Chen JL; Department of Gastroenterology, South Campus of Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201499, China.
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Źródło :
Yi chuan = Hereditas [Yi Chuan] 2021 Jan 20; Vol. 43 (1), pp. 84-93.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Epigenesis, Genetic*
CCAAT-Enhancer-Binding Proteins/*physiology
Intestines/*growth & development
Ubiquitin-Protein Ligases/*physiology
Animals ; CCAAT-Enhancer-Binding Proteins/genetics ; Gene Deletion ; Mice ; Mice, Knockout ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
Hypermethylation of WNT3A gene and non-syndromic cleft lip and/or palate in association with in utero exposure to lead: A mediation analysis.
Autorzy :
Yang W; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Guo Y; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Ni W; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Tian T; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Jin L; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Liu J; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Li Z; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Ren A; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Wang L; Institute of Reproductive and Child Health, NHC Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jan 15; Vol. 208, pp. 111415. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Cleft Lip/*genetics
Cleft Palate/*genetics
Hazardous Substances/*toxicity
Lead/*toxicity
Wnt3A Protein/*genetics
Animals ; Case-Control Studies ; Genotype ; Humans ; Male ; Mediation Analysis ; Mice
Czasopismo naukowe
Tytuł :
The associations of multiple metals mixture with accelerated DNA methylation aging.
Autorzy :
Xiao L; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Zan G; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Feng X; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Bao Y; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Huang S; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Luo X; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Xu X; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Zhang Z; School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Yang X; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China; Department of Public Health, School of Medicine, Guangxi University of Science and Technology, Liuzhou, Guangxi, China. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 Jan 15; Vol. 269, pp. 116230. Date of Electronic Publication: 2020 Dec 05.
Typ publikacji :
Journal Article
MeSH Terms :
Aging*
DNA Methylation*
Aged ; Aged, 80 and over ; Bayes Theorem ; Humans ; Metals ; Middle Aged ; Pilot Projects
Czasopismo naukowe
Tytuł :
Screening inhibitors for blocking UHRF1-methylated DNA interaction with capillary electrophoresis.
Autorzy :
Lou C; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China; School of physical science and technology, ShanghaiTech University, Haike Road 100, Shanghai, 200120, China; University of Chinese Academy of Sciences.
Ye X; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China; School of physical science and technology, ShanghaiTech University, Haike Road 100, Shanghai, 200120, China; University of Chinese Academy of Sciences.
Chen G; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Road, Shanghai 201210, China.
Zhu J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Road, Shanghai 201210, China.
Kang J; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China; School of physical science and technology, ShanghaiTech University, Haike Road 100, Shanghai, 200120, China. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Jan 11; Vol. 1636, pp. 461790. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Screening Assays, Antitumor*
Antineoplastic Agents/*analysis
Antineoplastic Agents/*pharmacology
CCAAT-Enhancer-Binding Proteins/*metabolism
DNA Methylation/*genetics
Electrophoresis, Capillary/*methods
Ubiquitin-Protein Ligases/*metabolism
Animals ; Antineoplastic Agents/chemistry ; DNA Methylation/drug effects ; Flavanones/chemistry ; Flavanones/pharmacology ; Humans ; Kinetics ; Mitoxantrone/chemistry ; Mitoxantrone/pharmacology ; Proanthocyanidins/chemistry ; Proanthocyanidins/pharmacology
Czasopismo naukowe
Tytuł :
[Evolutionary Aspects of Genomic Imprinting].
Autorzy :
Sazhenova EA; Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, 634050 Russia.; .
Lebedev IN; Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, 634050 Russia.
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2021 Jan-Feb; Vol. 55 (1), pp. 3-19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Methylation*
Genomic Imprinting*/genetics
Animals ; Female ; Mutation ; Pregnancy
Czasopismo naukowe
Tytuł :
Interaction Between microRNA and DNA Methylation in Atherosclerosis.
Autorzy :
Tao J; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Xia L; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Cai Z; Department of Pediatrics and The First Affiliated Hospital of University of South China, Hengyang, China.
Liang L; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Chen Y; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Meng J; Functional Department, The First Affiliated Hospital of University of South China, Hengyang, China.
Wang Z; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Jan; Vol. 40 (1), pp. 101-115. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Methylation*
Atherosclerosis/*genetics
MicroRNAs/*genetics
Animals ; Atherosclerosis/metabolism ; Humans ; MicroRNAs/metabolism
Czasopismo naukowe
Tytuł :
Matrix stiffness epigenetically regulates the oncogenic activation of the Yes-associated protein in gastric cancer.
Autorzy :
Jang M; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
An J; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Oh SW; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Lim JY; Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim J; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Choi JK; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. .
Cheong JH; Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. .
Kim P; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. .; Institute for Health Science and Technology, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. .
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Źródło :
Nature biomedical engineering [Nat Biomed Eng] 2021 Jan; Vol. 5 (1), pp. 114-123. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Carcinogenesis*/genetics
Carcinogenesis*/metabolism
DNA Methylation*/genetics
DNA Methylation*/physiology
Extracellular Matrix*/chemistry
Extracellular Matrix*/genetics
Extracellular Matrix*/metabolism
Stomach Neoplasms*/genetics
Stomach Neoplasms*/metabolism
Stomach Neoplasms*/physiopathology
Transcription Factors*/genetics
Transcription Factors*/metabolism
Cell Line, Tumor ; Epigenesis, Genetic/genetics ; Epigenesis, Genetic/physiology ; Humans ; Mechanotransduction, Cellular/genetics ; Mechanotransduction, Cellular/physiology ; Tumor Microenvironment/genetics ; Tumor Microenvironment/physiology
Czasopismo naukowe
Tytuł :
Methylation of the Sclerostin (SOST) Gene in Serum Free DNA: A New Bone Biomarker?
Autorzy :
Del Real A; Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain.
Perez-Campo FM; Department of Molecular Biology, University of Cantabria-IDIVAL, Santander, Spain.
Perez-Nuñez MI; Department of Traumatology/Hospital U.M. Valdecilla, University of Cantabria, Santander, Spain.
Sañudo C; Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain.
Santurtun A; Unit of Legal Medicine, Department of Physiology and Pharmacology, University of Cantabria, Santander, Spain.
Garcia-Ibarbia C; Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain.
Garcia-Unzueta MT; Service of Clinical Biochemistry, Hospital U.M. Valdecilla, University of Cantabria, IDIVAL, Santander, Spain.
Fraga MF; Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA), Nanomaterials and Nanotechnology Research Center (CINN-CSIC), University of Oviedo, Asturias, Spain.
Fernandez AF; Institute of Oncology of Asturias (IUOPA), ISPA-HUCA. Fundación para la Investigación Biosanitaria de Asturias (FINBA), Asturias, Spain.
Valero MC; Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain.
Laguna E; Department of Molecular Biology, University of Cantabria-IDIVAL, Santander, Spain.
Riancho JA; Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain.
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Źródło :
Genetic testing and molecular biomarkers [Genet Test Mol Biomarkers] 2021 Jan; Vol. 25 (1), pp. 42-47. Date of Electronic Publication: 2020 Dec 28.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Signal Transducing*
Arthroplasty, Replacement, Hip*
DNA Methylation*
Promoter Regions, Genetic*
Cell-Free Nucleic Acids/*metabolism
Osteoporosis/*blood
Aged ; Aged, 80 and over ; Biomarkers/metabolism ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development.
Autorzy :
Sen M; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
Mooijman D; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.; Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Chialastri A; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.; Center for Bioengineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.
Boisset JC; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands.
Popovic M; Ghent-Fertility and Stem cell Team (G-FaST), Department of Reproductive Medicine, Ghent University Hospital, 9000, Ghent, Belgium.
Heindryckx B; Ghent-Fertility and Stem cell Team (G-FaST), Department of Reproductive Medicine, Ghent University Hospital, 9000, Ghent, Belgium.
Chuva de Sousa Lopes SM; Ghent-Fertility and Stem cell Team (G-FaST), Department of Reproductive Medicine, Ghent University Hospital, 9000, Ghent, Belgium.; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands.
Dey SS; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA. .; Center for Bioengineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA. .; Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA, 93106, USA. .
van Oudenaarden A; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Utrecht, The Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 24; Vol. 12 (1), pp. 1286. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Demethylation*
DNA Methylation/*physiology
Animals ; Blastocyst/metabolism ; DNA (Cytosine-5-)-Methyltransferase 1/deficiency ; DNA (Cytosine-5-)-Methyltransferase 1/genetics ; DNA Methylation/genetics ; Embryonic Development/genetics ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism ; Female ; Humans ; Mice ; Mice, Knockout ; Pregnancy
Czasopismo naukowe
Tytuł :
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development.
Autorzy :
Yang Y; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.
Fan X; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.
Yan J; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Chen M; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.
Zhu M; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.
Tang Y; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.
Liu S; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.
Tang Z; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Research Centre of Animal Nutritional Genomics, State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China.; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.; GuangXi Engineering Centre for Resource Development of Bama Xiang Pig, Bama 547500, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Feb 22; Vol. 49 (3), pp. 1313-1329.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Epigenome*
Muscle Development/*genetics
Muscle, Skeletal/*embryology
Muscle, Skeletal/*growth & development
Animals ; Cell Line ; CpG Islands ; Epigenesis, Genetic ; Female ; Male ; Muscle, Skeletal/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Sex Characteristics ; Sp1 Transcription Factor/metabolism ; Swine ; Transcriptome
Czasopismo naukowe
Tytuł :
Differential promoter methylation and G-712A polymorphism of brain-derived neurotrophic factor in post-traumatic stress disorder patients of Li and Han populations in Hainan province.
Autorzy :
Guo J; Department of Hepatobiliary Surgery, Central South University Xiangya School of Medical Affiliated Haikou Hospital, Haikou 570208, Hainan, PR China.
Yang Y; Department of Hepatobiliary Surgery, Central South University Xiangya School of Medical Affiliated Haikou Hospital, Haikou 570208, Hainan, PR China.
Jiang X; Psychological Research Center, Hainan General Hospital, Haikou 570311, Hainan, PR China.
Guo M; Psychological Research Center, Hainan General Hospital, Haikou 570311, Hainan, PR China. Electronic address: .
Li X; The Third People's Hospital of Hubei Province, Wuhan 430032, Hubei, PR China.
Huang P; University of South China, Hengyang 421001, Hunan, PR China.
Liu Z; Psychological Research Center, Hainan General Hospital, Haikou 570311, Hainan, PR China.
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145192. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Polymorphism, Single Nucleotide*
Promoter Regions, Genetic*
Brain-Derived Neurotrophic Factor/*genetics
Stress Disorders, Post-Traumatic/*genetics
Adolescent ; Adult ; Asian Continental Ancestry Group/genetics ; Brain-Derived Neurotrophic Factor/blood ; Case-Control Studies ; China ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Minority Groups ; Regression Analysis ; Stress Disorders, Post-Traumatic/ethnology ; Surveys and Questionnaires ; Young Adult
Czasopismo naukowe
Tytuł :
Hypomethylation of the XRE -1383 site is associated with the upregulation of CYP1A1 in gastric adenocarcinoma.
Autorzy :
Sadeghi-Amiri L; Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, Sari, Islamic Republic of Iran.
Barzegar A; Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, Sari, Islamic Republic of Iran. Electronic address: .
Nikbakhsh-Zati N; Department of Surgery, Faculty of Medicine, Babol University of Medical Sciences, Babol, Islamic Republic of Iran.
Mehraban P; Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, Sari, Islamic Republic of Iran.
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145216. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Up-Regulation*
Adenocarcinoma/*genetics
Cytochrome P-450 CYP1A1/*genetics
Stomach Neoplasms/*genetics
Cell Line, Tumor ; Female ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł :
[Research progress on the correlation between abnormal sperm DNA methylation and semen quality].
Autorzy :
Chen W; Department of Urology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China. ; .
Yu D
Liu Y
Wu Z
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Źródło :
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2021 Feb 10; Vol. 38 (2), pp. 188-193.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Methylation*
Infertility, Male*/genetics
Spermatozoa/*pathology
Humans ; Male ; Semen Analysis ; Sperm Count ; Spermatogenesis
Czasopismo naukowe
Tytuł :
Proteomic and Genomic Methylation Signatures of Idiopathic Subglottic Stenosis.
Autorzy :
Schoeff SS; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Shi X; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Young WG; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Whited CW; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Soni RS; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Liu P; Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Ong IM; Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.; Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Dailey SH; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Welham NV; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
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Źródło :
The Laryngoscope [Laryngoscope] 2021 Feb; Vol. 131 (2), pp. E540-E546. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Proteomics*/methods
Laryngostenosis/*etiology
Adult ; Aged ; Biomarkers ; Biopsy ; Biotin/metabolism ; Case-Control Studies ; Female ; Humans ; Laryngostenosis/genetics ; Laryngostenosis/metabolism ; Laryngostenosis/pathology ; Larynx/metabolism ; Larynx/pathology ; Middle Aged
Czasopismo naukowe
Tytuł :
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
Autorzy :
Bamezai S; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
Demir D; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
Pulikkottil AJ; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
Ciccarone F; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy.
Fischbein E; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
Sinha A; Basepair, New York, NY, USA.
Borga C; Department of Women's and Children's Health, University of Padova, Padova, Italy.
Te Kronnie G; Department of Women's and Children's Health, University of Padova, Padova, Italy.
Meyer LH; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
Mohr F; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
Götze M; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.
Caiafa P; Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, Rome, Italy.
Debatin KM; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
Döhner K; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
Döhner H; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
González-Menéndez I; Institute of Pathology, University of Tübingen, 72076, Tübingen, Germany.
Quintanilla-Fend L; Institute of Pathology, University of Tübingen, 72076, Tübingen, Germany.
Herold T; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Center Munich, German Center for Environmental Health (HMGU), Munich, Germany.
Jeremias I; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Center Munich, German Center for Environmental Health (HMGU), Munich, Germany.; Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig Maximilians University, Munich, Germany.; German Consortium for Translational Cancer Research (DKTK), Partnering Site Munich, Munich, Germany.
Feuring-Buske M; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany.; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
Buske C; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany. .
Rawat VPS; Institute of Experimental Cancer Research, University Hospital of Ulm, Ulm, Germany. .
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Źródło :
Leukemia [Leukemia] 2021 Feb; Vol. 35 (2), pp. 389-403. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Gene Expression Regulation, Leukemic*
DNA-Binding Proteins/*physiology
Mixed Function Oxygenases/*metabolism
Phthalazines/*pharmacology
Piperazines/*pharmacology
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*pathology
Proto-Oncogene Proteins/*metabolism
Proto-Oncogene Proteins/*physiology
Animals ; Apoptosis ; Cell Proliferation ; Histones ; Humans ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Mixed Function Oxygenases/genetics ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Promoter Regions, Genetic ; Proto-Oncogene Proteins/genetics ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe

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