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Wyszukujesz frazę ""DNA-Binding Proteins"" wg kryterium: Temat


Tytuł:
Target-DBPPred: An intelligent model for prediction of DNA-binding proteins using discrete wavelet transform based compression and light eXtreme gradient boosting.
Autorzy:
Ali F; Department of Elementary and Secondary Education, Peshawar, Khyber Pakhtunkhwa, Pakistan; School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China. Electronic address: .
Kumar H; Department of Computer Science, College of Computer Science, King Khalid University, Abha, Saudi Arabia.
Patil S; Symbiosis Institute of Technology, Symbiosis Centre for Applied Artificial Intelligence, Symbiosis International University, Pune, India.
Kotecha K; Symbiosis Institute of Technology, Symbiosis Centre for Applied Artificial Intelligence, Symbiosis International University, Pune, India. Electronic address: .
Banjar A; Department of Information Systems, College of Computer Science and Engineering, University of Jeddah, Jeddah, Saudi Arabia.
Daud A; Key Laboratory of Oceanographic Big Data Mining & Application of Zhejiang Province, School of Information Engineering, Zhejiang Ocean University, Zhoushan, 316022, China; Department of Computer Science and Artificial Intelligence, University of Jeddah, Jeddah, Saudi Arabia. Electronic address: .
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Źródło:
Computers in biology and medicine [Comput Biol Med] 2022 Jun; Vol. 145, pp. 105533. Date of Electronic Publication: 2022 Apr 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA-Binding Proteins*/chemistry
DNA-Binding Proteins*/metabolism
Wavelet Analysis*
Algorithms ; Computational Biology/methods ; DNA/chemistry ; Databases, Protein ; Humans ; Position-Specific Scoring Matrices ; Support Vector Machine
Czasopismo naukowe
Tytuł:
Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes.
Autorzy:
Bochyńska A; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Stenzel AT; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Sayadi Boroujeni R; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Kuo CC; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.; Interdisciplinary Center for Clinical Research (IZKF), Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Barsoum M; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Liang W; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Bussmann P; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Costa IG; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Lüscher-Firzlaff J; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
Lüscher B; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen, Germany.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Aug 12; Vol. 50 (14), pp. 7889-7905.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Myeloid-Lymphoid Leukemia Protein*/metabolism
Animals ; Histone-Lysine N-Methyltransferase/genetics ; Histone-Lysine N-Methyltransferase/metabolism ; Histones/genetics ; Histones/metabolism ; Lysine/metabolism ; Mice ; Nuclear Proteins/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
53BP1-mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling.
Autorzy:
Tsaridou S; Department of Biology, School of Medicine, University of Patras, Patras, Greece.
Velimezi G; Department of Biology, School of Medicine, University of Patras, Patras, Greece.; Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Willenbrock F; Department of Oncology, University of Oxford, Oxford, UK.
Chatzifrangkeskou M; Department of Oncology, University of Oxford, Oxford, UK.
Elsayed W; Institute of Molecular Biology (IMB), Mainz, Germany.
Panagopoulos A; Department of Biology, School of Medicine, University of Patras, Patras, Greece.
Karamitros D; Department of Physiology, School of Medicine, University of Patras, Patras, Greece.
Gorgoulis V; Biomedical Research Foundation of the Academy of Athens, Athens, Greece.; Laboratory of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.; Faculty of Biology, Medicine and Health, Manchester Academic Health Centre, University of Manchester, Manchester, UK.; Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
Lygerou Z; Department of Biology, School of Medicine, University of Patras, Patras, Greece.
Roukos V; Department of Biology, School of Medicine, University of Patras, Patras, Greece.; Institute of Molecular Biology (IMB), Mainz, Germany.
O'Neill E; Department of Oncology, University of Oxford, Oxford, UK.
Pefani DE; Department of Biology, School of Medicine, University of Patras, Patras, Greece.
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Źródło:
EMBO reports [EMBO Rep] 2022 Aug 03; Vol. 23 (8), pp. e54483. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Breaks, Double-Stranded*
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Tumor Suppressor Proteins/*metabolism
Ataxia Telangiectasia Mutated Proteins/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; DNA Damage ; DNA Repair ; DNA, Ribosomal/genetics ; Genomic Instability ; Humans ; Phosphorylation ; Signal Transduction/genetics ; Tumor Suppressor p53-Binding Protein 1/genetics ; Tumor Suppressor p53-Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł:
A cardiac-null mutation of Prdm16 causes hypotension in mice with cardiac hypertrophy via increased nitric oxide synthase 1.
Autorzy:
Kang JO; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Korea.
Ha TW; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Korea.
Jung HU; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Korea.
Lim JE; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Korea.
Oh B; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Korea.
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Źródło:
PloS one [PLoS One] 2022 Jul 21; Vol. 17 (7), pp. e0267938. Date of Electronic Publication: 2022 Jul 21 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Heart Failure*/etiology
Hypotension*/complications
Hypotension*/genetics
Hypotension*/metabolism
Nitric Oxide Synthase Type I*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Cardiomegaly/etiology ; Female ; Humans ; Loss of Function Mutation ; Mice ; Mice, Knockout ; Myocardium/metabolism ; Nitric Oxide/metabolism
Czasopismo naukowe
Tytuł:
The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis.
Autorzy:
De Marco Zompit M; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland.
Esteban MT; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland.
Mooser C; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland.
Adam S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
Rossi SE; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
Jeanrenaud A; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland.
Leimbacher PA; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland.
Fink D; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland.
Shorrocks AK; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Blackford AN; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Durocher D; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Stucki M; Department of Gynecology, University of Zurich and University Hospital Zurich, Schlieren, Switzerland. .
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Źródło:
Nature communications [Nat Commun] 2022 Jul 16; Vol. 13 (1), pp. 4143. Date of Electronic Publication: 2022 Jul 16.
Typ publikacji:
Journal Article
MeSH Terms:
Autoantigens*/genetics
Autoantigens*/metabolism
Carrier Proteins*/genetics
Carrier Proteins*/metabolism
DNA Repair*
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Intracellular Signaling Peptides and Proteins*/genetics
Intracellular Signaling Peptides and Proteins*/metabolism
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Nuclear Proteins*/genetics
Nuclear Proteins*/metabolism
Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Chromosomal Instability ; DNA ; Humans ; Mitosis/physiology
Czasopismo naukowe
Tytuł:
Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention.
Autorzy:
Wang X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Han M; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.; Medical Integration and Practice Center, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.
Wang S; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.; University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, PA, USA.
Sun Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Zhao W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Xue Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Liang X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Huang B; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Li G; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Chen A; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Li X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.
Wang J; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 250012, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, 250117, China and Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway.
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Źródło:
Theranostics [Theranostics] 2022 Jul 11; Vol. 12 (12), pp. 5451-5469. Date of Electronic Publication: 2022 Jul 11 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Glioblastoma*/genetics
Glioblastoma*/pathology
Introns*/genetics
RNA Splicing Factors*/genetics
RNA Splicing Factors*/metabolism
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Animals ; Cell Line, Tumor ; Cell Proliferation ; Cysteine-Rich Protein 61/genetics ; Cysteine-Rich Protein 61/metabolism ; Disease Progression ; Gene Expression Regulation, Neoplastic/genetics ; Glutathione Peroxidase ; Humans ; Mice ; RNA Precursors/metabolism ; RNA, Messenger/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
A Method for In Situ Reverse Genetic Analysis of Proteins Involved mtDNA Replication.
Autorzy:
Kozhukhar N; Department of Physiology and Cell Biology, University of South Alabama, Mobile, AL 36688, USA.
Spadafora D; Department of Physiology and Cell Biology, University of South Alabama, Mobile, AL 36688, USA.
Rodriguez YAR; Department of Physiology and Cell Biology, University of South Alabama, Mobile, AL 36688, USA.
Alexeyev MF; Department of Physiology and Cell Biology, University of South Alabama, Mobile, AL 36688, USA.
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Źródło:
Cells [Cells] 2022 Jul 11; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 11.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
DNA, Mitochondrial/genetics ; Humans ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Reverse Genetics
Czasopismo naukowe
Tytuł:
Ibuprofen Alleviates Acute Pancreatitis- (AP-) Induced Myocardial Injury by Inhibiting AIM2.
Autorzy:
Chen K; Department of Gastroenterology, Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan, Hubei 430030, China.
Wang S; Emergency Department, Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan, Hubei 430030, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Jul 08; Vol. 2022, pp. 8801484. Date of Electronic Publication: 2022 Jul 08 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/antagonists & inhibitors
DNA-Binding Proteins*/biosynthesis
DNA-Binding Proteins*/genetics
Ibuprofen*/pharmacology
Pancreatitis*/chemically induced
Pancreatitis*/drug therapy
Pancreatitis*/genetics
Pancreatitis*/metabolism
Acute Disease ; Animals ; Rats ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Low expression of PRDM5 predicts poor prognosis of esophageal squamous cell carcinoma.
Autorzy:
Guo J; Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Yang Q; Cancer Research Center Nantong, Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Wei S; Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Shao J; Cancer Research Center Nantong, Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Zhao T; Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Guo L; Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Liu J; Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Chen J; Department of Oncology, Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China.
Wang G; Department of Radiation Oncology, Affiliated Tumor Hospital of Nantong University, Nantong Tumor Hospital, Nantong, Jiangsu, China. .
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Źródło:
BMC cancer [BMC Cancer] 2022 Jul 07; Vol. 22 (1), pp. 745. Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/pathology
Esophageal Squamous Cell Carcinoma*/genetics
Esophageal Squamous Cell Carcinoma*/pathology
Transcription Factors*/genetics
Transcription Factors*/metabolism
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Kaplan-Meier Estimate ; Prognosis ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Effect of In Vitro Solvation Conditions on Inter- and Intramolecular Assembly of Full-Length TDP-43.
Autorzy:
Doke AA; Physical and Materials Chemistry Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Jha SK; Physical and Materials Chemistry Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
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Źródło:
The journal of physical chemistry. B [J Phys Chem B] 2022 Jul 07; Vol. 126 (26), pp. 4799-4813. Date of Electronic Publication: 2022 Jun 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyotrophic Lateral Sclerosis*/metabolism
DNA-Binding Proteins*/chemistry
DNA-Binding Proteins*/metabolism
Amyloid/chemistry ; Amyloid/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity.
Autorzy:
Moretti M; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Marzi I; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Cantarutti C; Department of Medical Area, University of Udine, 33100 Udine, Italy.
Vivoli Vega M; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK.
Mandaliti W; Department of Medical Area, University of Udine, 33100 Udine, Italy.
Mimmi MC; Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.
Bemporad F; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Corazza A; Department of Medical Area, University of Udine, 33100 Udine, Italy.; INBB, Viale Medaglie d'Oro 305, 00136 Roma, Italy.
Chiti F; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jul 05; Vol. 27 (13). Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
DNA-Binding Proteins*/chemistry
DNA-Binding Proteins*/metabolism
Frontotemporal Lobar Degeneration*/metabolism
Dimerization ; Humans ; Inclusion Bodies/metabolism ; Protein Aggregates ; Protein Conformation, beta-Strand ; Protein Domains ; Protein Folding
Czasopismo naukowe
Tytuł:
Sequence, structure, and function of the Dps DNA-binding protein from Deinococcus wulumuqiensis R12.
Autorzy:
Chen Y; College of Food Science and Light Industry, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China.; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Yang Z; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Zhou X; College of Food Science and Light Industry, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Jin M; College of Food Science and Light Industry, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Dai Z; College of Food Science and Light Industry, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Ming D; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Zhang Z; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China. .; Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences/Xinjiang Key Laboratory of Special Environmental Microbiology, Ürümqi, 830091, Xinjiang, China. .
Zhu L; School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, China. .
Jiang L; College of Food Science and Light Industry, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2022 Jul 02; Vol. 21 (1), pp. 132. Date of Electronic Publication: 2022 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Hydrogen Peroxide*
Bacterial Proteins/metabolism ; DNA ; Deinococcus
SCR Organism:
Deinococcus wulumuqiensis
Czasopismo naukowe
Tytuł:
Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology.
Autorzy:
Rasmussen SV; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
Jin JX; Division of Translational Pediatric Sarcoma Research, Hopp Children's Cancer Center (KiTZ), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
Bickford LR; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
Woods AD; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
Sahm F; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Crawford KA; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
Nagamori K; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
Goto H; Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama, Japan.
Torres KE; Sarcoma Surgical Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
Sidoni A; Section of Pathology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Rudzinski ER; Department of Pathology, Seattle Children's Hospital, Seattle, Washington, USA.
Thway K; Sarcoma Unit, Royal Marsden Hospital, Belmont, UK.; Division of Molecular Pathology, Institute of Cancer Research, London, UK.
Jones RL; Sarcoma Unit, Royal Marsden Hospital, Belmont, UK.; Division of Clinical Studies, Institute of Cancer Research, London, UK.
Ciulli A; School of Life Sciences, University of Dundee, Dundee, UK.
Wright H; Omics Data Automation, Beaverton, Oregon, USA.
Lathara M; Omics Data Automation, Beaverton, Oregon, USA.
Srinivasa G; Omics Data Automation, Beaverton, Oregon, USA.
Kannan K; Omics Data Automation, Beaverton, Oregon, USA.
Huang PH; Sarcoma Unit, Royal Marsden Hospital, Belmont, UK.; Division of Molecular Pathology, Institute of Cancer Research, London, UK.
Grünewald TGP; Division of Translational Pediatric Sarcoma Research, Hopp Children's Cancer Center (KiTZ), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Berlow NE; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
Keller C; Children's Cancer Therapy Development Institute, Beaverton, Oregon, USA.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Jul; Vol. 12 (7), pp. e961.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
DNA-Binding Proteins*/therapeutic use
Sarcoma*/drug therapy
Sarcoma*/genetics
Sarcoma*/pathology
Adolescent ; Child ; Chromosomal Proteins, Non-Histone/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; Chromosomal Proteins, Non-Histone/therapeutic use ; Genomics ; Humans ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription Factors/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł:
Mutations linked to neurological disease enhance self-association of low-complexity protein sequences.
Autorzy:
Zhou X; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Sumrow L; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Tashiro K; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Sutherland L; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Liu D; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Qin T; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Kato M; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Institute for Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology, Inage, Chiba, 263-8555, Japan.
Liszczak G; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
McKnight SL; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Jul; Vol. 377 (6601), pp. eabn5582. Date of Electronic Publication: 2022 Jul 01.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/genetics
Charcot-Marie-Tooth Disease*/genetics
DNA-Binding Proteins*/chemistry
DNA-Binding Proteins*/genetics
Frontotemporal Dementia*/genetics
Cells, Cultured ; Humans ; Mutation, Missense ; Protein Domains ; Protein Folding ; Protein Stability
Czasopismo naukowe
Tytuł:
Ino80 is required for H2A.Z eviction from hypha-specific promoters and hyphal development of Candida albicans.
Autorzy:
Zhao Q; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Dai B; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Wu H; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Zhu W; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
Chen J; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
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Źródło:
Molecular microbiology [Mol Microbiol] 2022 Jul; Vol. 118 (1-2), pp. 92-104. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATPases Associated with Diverse Cellular Activities*/genetics
ATPases Associated with Diverse Cellular Activities*/metabolism
Candida albicans*/enzymology
Candida albicans*/genetics
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Histones*/genetics
Histones*/metabolism
Animals ; Chromatin Assembly and Disassembly ; Hyphae/genetics ; Hyphae/metabolism ; Mice ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Tytuł:
PBRM1 deficiency oncogenic addiction is associated with activated AKT-mTOR signalling and aerobic glycolysis in clear cell renal cell carcinoma cells.
Autorzy:
Tang Y; Department of Medical Genetics, Zunyi Medical University, Zunyi, China.; Key Laboratory of Gene Detection and Treatment in Guizhou Province, Zunyi, China.
Jin YH; Department of Medical Genetics, Zunyi Medical University, Zunyi, China.; Key Laboratory of Gene Detection and Treatment in Guizhou Province, Zunyi, China.
Li HL; Department of Medical Genetics, Zunyi Medical University, Zunyi, China.
Xin H; Department of Medical Genetics, Zunyi Medical University, Zunyi, China.; Key Laboratory of Gene Detection and Treatment in Guizhou Province, Zunyi, China.
Chen JD; Department of Urology, University of Rochester Medical Center, Rochester, New York, USA.; Exploring Health LLC, Guangzhou, China.
Li XY; Department of Medical Genetics, Zunyi Medical University, Zunyi, China.
Pan YF; Department of Medical Genetics, Zunyi Medical University, Zunyi, China.; Key Laboratory of Gene Detection and Treatment in Guizhou Province, Zunyi, China.
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Źródło:
Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Jul; Vol. 26 (14), pp. 3837-3849. Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Renal Cell*/pathology
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Kidney Neoplasms*/pathology
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Glycolysis/genetics ; Humans ; Oncogene Addiction ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
The activator/repressor Hap1 binds to the yeast eIF5A-encoding gene TIF51A to adapt its expression to the mitochondrial functional status.
Autorzy:
Barba-Aliaga M; Instituto de Biotecnología y Biomedicina (Biotecmed), Universitat de València, Spain.; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universitat de València, Spain.
Alepuz P; Instituto de Biotecnología y Biomedicina (Biotecmed), Universitat de València, Spain.; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universitat de València, Spain.
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Źródło:
FEBS letters [FEBS Lett] 2022 Jul; Vol. 596 (14), pp. 1809-1826. Date of Electronic Publication: 2022 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Eukaryotic Initiation Factor-5*/genetics
Eukaryotic Initiation Factor-5*/metabolism
Mitochondria*/genetics
Mitochondria*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Functional Status ; Humans ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism
Czasopismo naukowe
Tytuł:
Activation of the AIM2 Receptor in Circulating Cells of Post-COVID-19 Patients With Signs of Lung Fibrosis Is Associated With the Release of IL-1α, IFN-α and TGF-β.
Autorzy:
Colarusso C; Department of Pharmacy, University of Salerno, Fisciano, Italy.
Terlizzi M; Department of Pharmacy, University of Salerno, Fisciano, Italy.
Maglio A; Department of Medicine and Surgery, University of Salerno, Baronissi, Italy.
Molino A; Department of Respiratory Medicine, Respiratory Division, University of Naples Federico II, Naples, Italy.
Candia C; Department of Respiratory Medicine, Respiratory Division, University of Naples Federico II, Naples, Italy.
Vitale C; Department of Medicine and Surgery, University of Salerno, Baronissi, Italy.
Hansbro PM; Centre for Inflammation, School of Life Sciences, Faculty of Science, Centenary Institute and University of Technology Sydney, Sydney, NSW, Australia.
Vatrella A; Department of Medicine and Surgery, University of Salerno, Baronissi, Italy.
Pinto A; Department of Pharmacy, University of Salerno, Fisciano, Italy.
Sorrentino R; Department of Pharmacy, University of Salerno, Fisciano, Italy.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jun 29; Vol. 13, pp. 934264. Date of Electronic Publication: 2022 Jun 29 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/blood
COVID-19*/immunology
COVID-19*/pathology
DNA-Binding Proteins*/blood
DNA-Binding Proteins*/immunology
Pulmonary Fibrosis*/blood
Pulmonary Fibrosis*/immunology
Pulmonary Fibrosis*/pathology
Pulmonary Fibrosis*/virology
Carrier Proteins ; Caspase 1/immunology ; Humans ; Inflammasomes/blood ; Inflammasomes/immunology ; Interferon-alpha/metabolism ; Leukocytes, Mononuclear/immunology ; SARS-CoV-2 ; Transforming Growth Factor beta/metabolism
SCR Disease Name:
post-acute COVID-19 syndrome
Czasopismo naukowe
Tytuł:
Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy.
Autorzy:
Krus KL; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; Medical Scientist Training Program, Washington University in St. Louis, St. Louis, MO 63110, USA.
Strickland A; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Yamada Y; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Devault L; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Schmidt RE; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Bloom AJ; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA; Needleman Center for Neurometabolism and Axonal Therapeutics, St. Louis, MO 63110, USA.
Milbrandt J; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110, USA; Needleman Center for Neurometabolism and Axonal Therapeutics, St. Louis, MO 63110, USA. Electronic address: .
DiAntonio A; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; Needleman Center for Neurometabolism and Axonal Therapeutics, St. Louis, MO 63110, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2022 Jun 28; Vol. 39 (13), pp. 111001.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
Amyotrophic Lateral Sclerosis*/metabolism
Amyotrophic Lateral Sclerosis*/pathology
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Stathmin*/deficiency
Stathmin*/genetics
Stathmin*/metabolism
Animals ; Mice ; Mice, Knockout ; Motor Neurons/metabolism ; Motor Neurons/pathology
Czasopismo naukowe
Tytuł:
Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4 T cells in ulcerative colitis.
Autorzy:
Xu HM; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Yuexiu District, No. 1, Panfu Road, Guangzhou, 510180, Guangdong, China.
Xu J; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Yuexiu District, No. 1, Panfu Road, Guangzhou, 510180, Guangdong, China.
Yang MF; Department of Hematology, Yantian District People's Hospital, Shenzhen, 518020, Guangdong, China.
Liang YJ; Shenzhen Kangning Hospital, Shenzhen, 518020, Guangdong, China.
Peng QZ; Department of Pathology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China.
Zhang Y; Department of Medical Administration, Huizhou Institute of Occupational Diseases Control and Prevention, Huizhou, 516000, Guangdong, China.
Tian CM; Department of Emergency, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China.
Nie YQ; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Yuexiu District, No. 1, Panfu Road, Guangzhou, 510180, Guangdong, China. .
Wang LS; Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Luohu District, No. 1017, Dongmen North Road, Shenzhen, 518020, Guangdong, China. .
Yao J; Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Luohu District, No. 1017, Dongmen North Road, Shenzhen, 518020, Guangdong, China. .
Li DF; Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Luohu District, No. 1017, Dongmen North Road, Shenzhen, 518020, Guangdong, China. .
Pokaż więcej
Źródło:
Journal of translational medicine [J Transl Med] 2022 Jun 27; Vol. 20 (1), pp. 289. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*/metabolism
CD8-Positive T-Lymphocytes*/metabolism
Colitis, Ulcerative*/genetics
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Epigenesis, Genetic*
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Colitis/chemically induced ; Colitis/genetics ; Colon/pathology ; Cytokines/metabolism ; DNA Methylation ; Dextran Sulfate/adverse effects ; Dextran Sulfate/metabolism ; Humans ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe

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