Temat: "DNA-Cytosine Methylases" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: In Arabidopsis thaliana Cd differentially impacts on hormone genetic pathways in the methylation defective ddc mutant compared to wild type.
Autorzy:: Pacenza M; Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, CS, Italy.
Muto A; Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, CS, Italy.
Chiappetta A; Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, CS, Italy.
Mariotti L; Department of Agriculture, Food and Environment, University of Pisa, Pisa, PI, Italy.
Talarico E; Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, CS, Italy.
Picciarelli P; Department of Agriculture, Food and Environment, University of Pisa, Pisa, PI, Italy.
Picardi E; Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari, Bari, BA, Italy.
Bruno L; Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, CS, Italy. .
Bitonti MB; Department of Biology, Ecology and Earth Science, University of Calabria, Arcavacata di Rende, CS, Italy.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 May 26; Vol. 11 (1), pp. 10965. Date of Electronic Publication: 2021 May 26.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Arabidopsis/*genetics
Arabidopsis Proteins/*physiology
Cadmium/*pharmacology
DNA-Cytosine Methylases/*physiology
Gene Expression Regulation, Plant/*drug effects
Methyltransferases/*physiology
Plant Growth Regulators/*genetics
Arabidopsis/drug effects ; Arabidopsis/growth & development ; Arabidopsis Proteins/genetics ; Base Sequence ; Cytokinins/biosynthesis ; Cytokinins/genetics ; DNA Methylation ; DNA, Plant/genetics ; DNA-Cytosine Methylases/deficiency ; DNA-Cytosine Methylases/genetics ; Genes, Plant ; Methyltransferases/deficiency ; Methyltransferases/genetics ; Mutation ; Plant Roots/growth & development ; RNA, Messenger/genetics ; RNA, Plant/genetics ; Soil Pollutants/pharmacology ; Stress, Physiological/genetics ; Transcriptome/drug effects

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Skocz do pozycji: 2.

Tytuł:: Genome-wide identification and analysis of DNA methyltransferase and demethylase gene families in Dendrobium officinale reveal their potential functions in polysaccharide accumulation.
Autorzy:: Yu Z; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China.; Economic Botany, Core Botanical Gardens, Chinese Academy of Sciences, Guangzhou, 510650, China.
Zhang G; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China.
Teixeira da Silva JA; Independent researcher, P. O. Box 7, Miki-cho post office, Ikenobe 3011-2, Miki-cho, Kagawa-ken, 761-0799, Japan.
Li M; Biodata Biotechnology Co. Ltd, Hefei, 230031, China.
Zhao C; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China.
He C; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China.
Si C; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China.
Zhang M; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China.
Duan J; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China. .; Economic Botany, Core Botanical Gardens, Chinese Academy of Sciences, Guangzhou, 510650, China. .; Pokaż więcej
Źródło:: BMC plant biology [BMC Plant Biol] 2021 Jan 06; Vol. 21 (1), pp. 21. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: DNA Methylation/*genetics
DNA-Cytosine Methylases/*genetics
Dendrobium/*enzymology
Dendrobium/*genetics
Oxidoreductases/*genetics
Polysaccharides/*genetics
Polysaccharides/*metabolism
Arabidopsis/genetics ; DNA-Cytosine Methylases/metabolism ; Gene Expression Regulation, Plant ; Genes, Plant ; Genome-Wide Association Study ; Oryza/genetics ; Oxidoreductases/metabolism

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Skocz do pozycji: 3.

Tytuł:: Cytosine-5 RNA methylation links protein synthesis to cell metabolism.
Autorzy:: Gkatza NA; Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Castro C; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Harvey RF; Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, United Kingdom.
Heiß M; Department of Chemistry, Ludwig-Maximilians-University Munich, Munich, Germany.
Popis MC; Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Blanco S; Cancer Cell Signaling and Metabolism Lab, Proteomics Unit CIC bioGUNE, Derio, Spain.; Molecular Mechanisms Program, Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC)-University of Salamanca, Salamanca, Spain.
Bornelöv S; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.
Sajini AA; Department of Biomedical Engineering, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Gleeson JG; Department of Neurosciences, San Diego School of Medicine, University of California, La Jolla, California, United States of America.
Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
West JA; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Kellner S; Department of Chemistry, Ludwig-Maximilians-University Munich, Munich, Germany.
Willis AE; Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, United Kingdom.
Dietmann S; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.
Frye M; Department of Genetics, University of Cambridge, Cambridge, United Kingdom.; German Cancer Center (Deutsches Krebsforschungszntrum), Heidelberg, Germany.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2019 Jun 14; Vol. 17 (6), pp. e3000297. Date of Electronic Publication: 2019 Jun 14 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA-Cytosine Methylases/*metabolism
Methyltransferases/*metabolism
Animals ; Cell Line ; Cytosine/metabolism ; DNA Methylation/physiology ; DNA-Cytosine Methylases/physiology ; Humans ; Mice ; Oxidative Stress/physiology ; Protein Biosynthesis/physiology ; RNA/metabolism ; RNA, Transfer/metabolism

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Skocz do pozycji: 4.

Tytuł:: CMT3 and SUVH4/KYP silence the exonic Evelknievel retroelement to allow for reconstitution of CMT1 mRNA.
Autorzy:: Yadav NS; French Associates Institute for Agriculture and Biotechnology of Drylands, Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, 84990, Midreshet Ben Gurion, Israel.
Khadka J; French Associates Institute for Agriculture and Biotechnology of Drylands, Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, 84990, Midreshet Ben Gurion, Israel.
Domb K; The School of Plant Sciences and Food Security, Tel-Aviv University, 69978, Tel Aviv, Israel.
Zemach A; The School of Plant Sciences and Food Security, Tel-Aviv University, 69978, Tel Aviv, Israel.
Grafi G; French Associates Institute for Agriculture and Biotechnology of Drylands, Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, 84990, Midreshet Ben Gurion, Israel. .; Pokaż więcej
Źródło:: Epigenetics & chromatin [Epigenetics Chromatin] 2018 Nov 16; Vol. 11 (1), pp. 69. Date of Electronic Publication: 2018 Nov 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Retroelements*
Arabidopsis/*genetics
Arabidopsis Proteins/*genetics
DNA (Cytosine-5-)-Methyltransferases/*genetics
DNA-Cytosine Methylases/*genetics
Histone-Lysine N-Methyltransferase/*genetics
Arabidopsis Proteins/metabolism ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; DNA Methylation ; DNA-Binding Proteins/genetics ; DNA-Cytosine Methylases/metabolism ; Gene Expression Regulation, Plant ; Gene Silencing ; Genome, Plant ; Histone-Lysine N-Methyltransferase/metabolism ; Mutation ; RNA, Messenger/genetics ; RNA, Plant/genetics ; Transcription Factors/genetics

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Skocz do pozycji: 5.

Tytuł:: Kinetic Basis of the Bifunctionality of SsoII DNA Methyltransferase.
Autorzy:: Timofeyeva NA; Siberian Branch of the Russian Academy of Sciences, Institute of Chemical Biology and Fundamental Medicine, Lavrentyev Ave., 8, 630090 Novosibirsk, Russia. na_.
Ryazanova AY; Belozersky Institute of Physico-Chemical Biology and Chemistry Department, Lomonosov Moscow State University, Leninskye Gory, 1, 119991 Moscow, Russia. .
Norkin MV; Belozersky Institute of Physico-Chemical Biology and Chemistry Department, Lomonosov Moscow State University, Leninskye Gory, 1, 119991 Moscow, Russia. .
Oretskaya TS; Belozersky Institute of Physico-Chemical Biology and Chemistry Department, Lomonosov Moscow State University, Leninskye Gory, 1, 119991 Moscow, Russia. .
Fedorova OS; Siberian Branch of the Russian Academy of Sciences, Institute of Chemical Biology and Fundamental Medicine, Lavrentyev Ave., 8, 630090 Novosibirsk, Russia. .
Kubareva EA; Belozersky Institute of Physico-Chemical Biology and Chemistry Department, Lomonosov Moscow State University, Leninskye Gory, 1, 119991 Moscow, Russia. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 May 16; Vol. 23 (5). Date of Electronic Publication: 2018 May 16.
Typ publikacji:: Journal Article
MeSH Terms:: Bacteria/*genetics
DNA, Bacterial/*chemistry
DNA, Bacterial/*metabolism
DNA-Cytosine Methylases/*metabolism
Bacteria/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Binding Sites ; DNA Methylation ; DNA, Bacterial/genetics ; DNA-Cytosine Methylases/chemistry ; Gene Expression Regulation, Bacterial ; Kinetics ; Molecular Conformation ; S-Adenosylmethionine/metabolism ; Transcription, Genetic

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Skocz do pozycji: 6.

Tytuł:: DNA methyltransferase CHROMOMETHYLASE3 prevents ONSEN transposon silencing under heat stress.
Autorzy:: Nozawa K; Graduate School of Life Science, Hokkaido University, Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido, Japan.
Chen J; Wisconsin Institute for Discovery & Laboratory of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Jiang J; Wisconsin Institute for Discovery & Laboratory of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Leichter SM; Wisconsin Institute for Discovery & Laboratory of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Yamada M; Graduate School of Life Science, Hokkaido University, Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido, Japan.
Suzuki T; College of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi, Japan.
Liu F; Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Ito H; Faculty of Science, Hokkaido University, Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido, Japan.
Zhong X; Wisconsin Institute for Discovery & Laboratory of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2021 Aug 19; Vol. 17 (8), pp. e1009710. Date of Electronic Publication: 2021 Aug 19 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Arabidopsis/*physiology
Arabidopsis Proteins/*genetics
DNA Transposable Elements/*ethics
DNA-Cytosine Methylases/*genetics
Arabidopsis/genetics ; DNA Methylation ; Gene Expression Regulation, Plant ; Gene Silencing ; Heat-Shock Response ; Sequence Analysis, DNA ; Transcription, Genetic

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Skocz do pozycji: 7.

Tytuł:: Lowering DNA binding affinity of SssI DNA methyltransferase does not enhance the specificity of targeted DNA methylation in E. coli.
Autorzy:: Ślaska-Kiss K; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary.
Zsibrita N; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary.; Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged, 6726, Hungary.
Koncz M; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary.; Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged, 6726, Hungary.
Albert P; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary.; Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged, 6726, Hungary.
Csábrádi Á; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary.
Szentes S; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary.
Kiss A; Biological Research Centre, Institute of Biochemistry, Laboratory of DNA-Protein Interactions, Eötvös Loránd Research Network (ELKH), Temesvári krt. 62, Szeged, 6726, Hungary. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jul 27; Vol. 11 (1), pp. 15226. Date of Electronic Publication: 2021 Jul 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Methylation*
DNA, Bacterial/*metabolism
DNA-Cytosine Methylases/*metabolism
Escherichia coli/*genetics
Base Sequence ; Binding Sites ; Protein Binding ; Zinc Fingers

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Skocz do pozycji: 8.

Tytuł:: Highly sensitive detection of M.SssI DNA methyltransferase activity using a personal glucose meter.
Autorzy:: Deng H; Department of Chemistry, National University of Singapore, Science Drive 3, Singapore, 117543, Singapore.; China National Tobacco Quality Supervision and Test Center, Zhengzhou, Henan, 450001, China.
Png
Gao Z; Department of Chemistry, National University of Singapore, Science Drive 3, Singapore, 117543, Singapore. .; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2016 Aug; Vol. 408 (21), pp. 5867-5872. Date of Electronic Publication: 2016 Jun 16.
Typ publikacji:: Journal Article
MeSH Terms:: Biosensing Techniques/*methods
Blood Glucose Self-Monitoring/*methods
DNA-Cytosine Methylases/*analysis
Electrochemical Techniques/*methods
Glucose/*analysis
DNA-Cytosine Methylases/metabolism ; Enzyme Assays/methods ; Glucose/metabolism ; HeLa Cells ; Humans ; Immobilized Nucleic Acids/chemistry ; Immobilized Nucleic Acids/metabolism ; Limit of Detection ; MCF-7 Cells ; Magnets/chemistry

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Skocz do pozycji: 9.

Tytuł:: The tumor suppressor Zinc finger protein 471 suppresses breast cancer growth and metastasis through inhibiting AKT and Wnt/β-catenin signaling.
Autorzy:: Tao C; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Luo J; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tang J; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou D; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Feng S; Hunan Province Key Laboratory of Tumor Cellular and Molecular Pathology, Cancer Research Institute, Hengyang School of Medicine, University of South China, Hengyang, China.
Qiu Z; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Putti TC; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Xiang T; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tao Q; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong and CUHK Shenzhen Research Institute, Hong Kong, China.
Li L; Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong and CUHK Shenzhen Research Institute, Hong Kong, China. lili_.
Ren G; Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2020 Nov 17; Vol. 12 (1), pp. 173. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Breast Neoplasms/*genetics
Neoplasm Metastasis/*genetics
Proto-Oncogene Proteins c-akt/*genetics
Repressor Proteins/*genetics
Wnt Signaling Pathway/*genetics
Animals ; Apoptosis/genetics ; Breast Neoplasms/pathology ; Cell Cycle Checkpoints/genetics ; Cell Line, Tumor/metabolism ; Cell Proliferation/genetics ; DNA Methylation ; DNA-Cytosine Methylases/metabolism ; Down-Regulation ; Epigenomics ; Epithelial-Mesenchymal Transition/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Genes, Tumor Suppressor ; Humans ; Mice ; Mice, Nude/genetics ; Models, Animal ; Neoplasm Metastasis/pathology ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-akt/metabolism ; Repressor Proteins/pharmacology ; Zinc Fingers/genetics

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Skocz do pozycji: 10.

Tytuł:: A 7-Deazaadenosylaziridine Cofactor for Sequence-Specific Labeling of DNA by the DNA Cytosine-C5 Methyltransferase M.HhaI.
Autorzy:: Kunkel F; Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen D-52056, Germany. Falk_.
Lurz R; Max-Planck-Institute for Molecular Genetics, Ihnestrasse 73, Berlin D-14195, Germany. .
Weinhold E; Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen D-52056, Germany. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2015 Nov 23; Vol. 20 (11), pp. 20805-22. Date of Electronic Publication: 2015 Nov 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aziridines/*chemistry
DNA/*chemistry
DNA-Cytosine Methylases/*chemistry
Tubercidin/*chemistry
Aziridines/chemical synthesis ; Binding Sites ; Biotin/chemistry ; Biotinylation ; Catalysis ; CpG Islands ; DNA/metabolism ; DNA Methylation ; DNA-Cytosine Methylases/metabolism ; Models, Molecular ; Molecular Conformation ; Nucleic Acid Conformation ; Oligodeoxyribonucleotides/chemistry ; Plasmids/chemistry ; Plasmids/ultrastructure ; Protein Binding

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Skocz do pozycji: 11.

Tytuł:: Functions that Protect Escherichia coli from Tightly Bound DNA-Protein Complexes Created by Mutant EcoRII Methyltransferase.
Autorzy:: Henderson ML; University Program in Genetics and Genomics, Duke University Medical Center, Durham NC, 27710, United States of America.
Kreuzer KN; University Program in Genetics and Genomics, Duke University Medical Center, Durham NC, 27710, United States of America; Department of Biochemistry, Duke University Medical Center, Durham NC, 27710, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 May 19; Vol. 10 (5), pp. e0128092. Date of Electronic Publication: 2015 May 19 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Mutation*
DNA, Bacterial/*metabolism
DNA-Cytosine Methylases/*metabolism
Escherichia coli/*enzymology
Escherichia coli Proteins/*metabolism
Anti-Bacterial Agents/pharmacology ; Chromosomes, Bacterial ; DNA Replication ; DNA-Cytosine Methylases/genetics ; Escherichia coli/drug effects ; Quinolones/pharmacology ; Recombination, Genetic

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Skocz do pozycji: 12.

Tytuł:: KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and is Resilient to TGFβ1 Activation.
Autorzy:: Gjaltema RAF; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.; MATRIX Research Group, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Goubert D; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.
Huisman C; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.
Pilar García Tobilla CD; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.
Koncz M; Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary.; Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Jellema PG; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.; MATRIX Research Group, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Wu D; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.
Brouwer U; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.; MATRIX Research Group, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Kiss A; Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary.
Verschure PJ; Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Bank RA; MATRIX Research Group, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Rots MG; Epigenetic Editing Laboratory, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 EA11, 9713 GZ Groningen, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 May 21; Vol. 21 (10). Date of Electronic Publication: 2020 May 21.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Silencing*
Heterochromatin/*metabolism
Kruppel-Like Transcription Factors/*metabolism
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase/*genetics
Adult ; Cells, Cultured ; DNA-Cytosine Methylases/genetics ; DNA-Cytosine Methylases/metabolism ; Epigenesis, Genetic ; HEK293 Cells ; Humans ; Kruppel-Like Transcription Factors/genetics ; MCF-7 Cells ; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase/metabolism ; Promoter Regions, Genetic ; Transcriptional Activation ; Transforming Growth Factor beta/metabolism

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Skocz do pozycji: 13.

Tytuł:: Analysis of cell growth and gene expression of porcine adipose tissue-derived mesenchymal stem cells as nuclear donor cell.
Autorzy:: Oh HJ; Department of Theriogenology and Biotechnology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University.
Park JE
Park EJ
Kim MJ
Kim GA
Rhee SH
Lim SH
Kang SK
Lee BC; Pokaż więcej
Źródło:: Development, growth & differentiation [Dev Growth Differ] 2014 Dec; Vol. 56 (9), pp. 595-604. Date of Electronic Publication: 2014 Oct 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Reprogramming*
Nuclear Transfer Techniques*
Adipose Tissue/*metabolism
DNA-Cytosine Methylases/*biosynthesis
Mesenchymal Stem Cells/*metabolism
Repressor Proteins/*biosynthesis
Adipose Tissue/cytology ; Animals ; DNA-Cytosine Methylases/genetics ; Female ; Gene Expression Regulation, Enzymologic ; Humans ; Mesenchymal Stem Cells/cytology ; Repressor Proteins/genetics ; Swine ; Swine, Miniature

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Skocz do pozycji: 14.

Tytuł:: Essential concepts are missing: Foreign DNA in food invades the organisms' cells and can lead to stochastic epigenetic alterations with a wide range of possible pathogenetic consequences.
Autorzy:: Doerfler W; Institute for Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, Schlossgarten 4, 91054, Erlangen, Germany. .; Institute of Genetics, University of Cologne, Cologne, Germany. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2020 Feb 07; Vol. 12 (1), pp. 21. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA/*genetics
DNA Methylation/*genetics
Disease/*genetics
Food Supply/*standards
Animals ; DNA/administration & dosage ; DNA/metabolism ; DNA-Cytosine Methylases/metabolism ; Epigenesis, Genetic ; Epigenomics ; Genome-Wide Association Study/methods ; Humans ; Mammals ; Mice

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Skocz do pozycji: 15.

Tytuł:: A model of pulldown alignments from SssI-treated DNA improves DNA methylation prediction.
Autorzy:: Moreland BS; Department of Physics, The Ohio State University, Columbus, OH, USA.; Present address: Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH,, USA.
Oman KM; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Bundschuh R; Department of Physics, The Ohio State University, Columbus, OH, USA. .; Department of Chemistry&Biochemistry, Division of Hematology, and Center for RNA Biology, The Ohio State University, Columbus, OH, USA. .; Pokaż więcej
Źródło:: BMC bioinformatics [BMC Bioinformatics] 2019 Aug 19; Vol. 20 (1), pp. 431. Date of Electronic Publication: 2019 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Models, Biological*
Sequence Alignment*
Computational Biology/*methods
DNA/*metabolism
DNA Methylation/*genetics
DNA-Cytosine Methylases/*metabolism
Algorithms ; Base Pairing ; Chromosomes, Human, Pair 7/genetics ; CpG Islands/genetics ; Genome, Human ; High-Throughput Nucleotide Sequencing ; Humans ; Methyl CpG Binding Domain ; Sequence Analysis, DNA/methods

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Skocz do pozycji: 16.

Tytuł:: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Autorzy:: Zwergel C; Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
Schnekenburger M; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, 9 rue Edward Steichen, L-2540, Luxembourg City, Luxembourg.
Sarno F; Department of Medicine of Precision, University of Studi della Campania Luigi Vanvitelli, Vico L. De Crecchio 7, 80138, Naples, Italy.
Battistelli C; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.
Manara MC; Laboratory of Experimental Oncology, IRCCS - Istituto Ortopedico Rizzoli, via di Barbiano, 1/10, Bologna, 40136, Italy.
Stazi G; Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
Mazzone R; Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
Fioravanti R; Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
Gros C; Center for High-Throughput Chemical Biology, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada.
Ausseil F; Pierre Fabre Laboratories, 3 Avenue Hubert Curien, Toulouse, 31100, France.
Florean C; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, 9 rue Edward Steichen, L-2540, Luxembourg City, Luxembourg.
Nebbioso A; Department of Medicine of Precision, University of Studi della Campania Luigi Vanvitelli, Vico L. De Crecchio 7, 80138, Naples, Italy.
Strippoli R; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.; National Institute for Infectious Diseases L. Spallanzani, IRCCS, Via Portuense, 292, Rome, 00149, Italy.
Ushijima T; Division of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Scotlandi K; Laboratory of Experimental Oncology, IRCCS - Istituto Ortopedico Rizzoli, via di Barbiano, 1/10, Bologna, 40136, Italy.
Tripodi M; Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.; National Institute for Infectious Diseases L. Spallanzani, IRCCS, Via Portuense, 292, Rome, 00149, Italy.; Pasteur Institute, Cenci-Bolognetti Foundation, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
Arimondo PB; Epigenetic Chemical Biology, Institut Pasteur, CNRS UMR3523, 28 rue du Docteur Roux, Paris, 75724, France.
Altucci L; Department of Medicine of Precision, University of Studi della Campania Luigi Vanvitelli, Vico L. De Crecchio 7, 80138, Naples, Italy.
Diederich M; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, 08826, Korea.
Mai A; Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy. .; Pasteur Institute, Cenci-Bolognetti Foundation, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy. .
Valente S; Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2019 May 06; Vol. 11 (1), pp. 68. Date of Electronic Publication: 2019 May 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Aminoquinolines/*chemical synthesis
Aminoquinolines/*pharmacology
DNA-Cytosine Methylases/*antagonists & inhibitors
Enzyme Inhibitors/*chemical synthesis
Enzyme Inhibitors/*pharmacology
Neoplasms/*metabolism
Aminoquinolines/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; DNA Methylation ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Enzyme Inhibitors/chemistry ; Epigenesis, Genetic ; Epithelial-Mesenchymal Transition/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; HCT116 Cells ; Humans ; Neoplasms/drug therapy ; Pyrimidines/chemistry

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Skocz do pozycji: 17.

Tytuł:: Flexibility of the linker between the domains of DNA methyltransferase SsoII revealed by small-angle X-ray scattering: implications for transcription regulation in SsoII restriction-modification system.
Autorzy:: Konarev PV; European Molecular Biology Laboratory, Hamburg Outstation, Hamburg, Germany.
Kachalova GS; Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, Russia.
Ryazanova AY; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Kubareva EA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Karyagina AS; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia; Gamaleya Institute of Epidemiology and Microbiology, Moscow, Russia; Institute of Agricultural Biotechnology, Russian Academy of Sciences, Moscow, Russia.
Bartunik HD; Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, Russia.
Svergun DI; European Molecular Biology Laboratory, Hamburg Outstation, Hamburg, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Apr 07; Vol. 9 (4), pp. e93453. Date of Electronic Publication: 2014 Apr 07 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcription, Genetic*
Bacterial Proteins/*chemistry
DNA, Bacterial/*chemistry
DNA-Cytosine Methylases/*chemistry
Bacterial Proteins/metabolism ; DNA, Bacterial/metabolism ; DNA-Cytosine Methylases/metabolism ; Protein Structure, Tertiary ; Structure-Activity Relationship ; X-Ray Diffraction

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Skocz do pozycji: 18.

Tytuł:: Metadynamics simulation study on the conformational transformation of HhaI methyltransferase: an induced-fit base-flipping hypothesis.
Autorzy:: Jin L; College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou 310018, China ; Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.
Ye F; College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Zhao D; Drug Design and Discovery Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Chen S; Drug Design and Discovery Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Zhu K; Drug Design and Discovery Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Zheng M; Drug Design and Discovery Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Jiang RW; Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.
Jiang H; Drug Design and Discovery Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Luo C; Drug Design and Discovery Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2014; Vol. 2014, pp. 304563. Date of Electronic Publication: 2014 Jun 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Conformation*
DNA/*genetics
DNA Methylation/*genetics
DNA-Cytosine Methylases/*genetics
Catalysis ; Catalytic Domain ; DNA-Cytosine Methylases/chemistry ; Hydrogen Bonding ; Models, Molecular ; Protein Structure, Quaternary ; S-Adenosylhomocysteine/metabolism

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Skocz do pozycji: 19.

Tytuł:: TALE-PvuII fusion proteins--novel tools for gene targeting.
Autorzy:: Yanik M; Institute for Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany.
Alzubi J; Institute for Cell and Gene Therapy, University Medical Center Freiburg, Freiburg, Germany ; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Lahaye T; ZMBP - General Genetics, University of Tuebingen, Tuebingen, Germany.
Cathomen T; Institute for Cell and Gene Therapy, University Medical Center Freiburg, Freiburg, Germany ; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Pingoud A; Institute for Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany.
Wende W; Institute for Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Dec 05; Vol. 8 (12), pp. e82539. Date of Electronic Publication: 2013 Dec 05 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA-Cytosine Methylases/*metabolism
Homeodomain Proteins/*metabolism
Recombinant Fusion Proteins/*metabolism
Binding Sites ; Cell Line ; DNA Cleavage ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; DNA-Cytosine Methylases/genetics ; Gene Targeting/methods ; Homeodomain Proteins/genetics ; Humans ; Models, Molecular ; Protein Conformation ; Protein Multimerization ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/toxicity ; Substrate Specificity

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Skocz do pozycji: 20.

Tytuł:: Complementation between inactive fragments of SssI DNA methyltransferase.
Autorzy:: Slaska-Kiss K; Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary.
Tímár E
Kiss A; Pokaż więcej
Źródło:: BMC molecular biology [BMC Mol Biol] 2012 May 30; Vol. 13, pp. 17. Date of Electronic Publication: 2012 May 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA-Cytosine Methylases/*metabolism
Amino Acid Sequence ; DNA Methylation ; DNA-Cytosine Methylases/chemistry ; DNA-Cytosine Methylases/genetics ; Escherichia coli/metabolism ; Molecular Sequence Data ; Plasmids/genetics ; Plasmids/metabolism ; Protein Structure, Tertiary ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Zinc Fingers

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