Temat: "DNA-Directed RNA Polymerases" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding.
Autorzy:: Amusengeri A; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.
Khan A; Department of Biochemistry, Abdul Wali Khan University Mardan (AWKUM), Mardan 23200, Pakistan.
Tastan Bishop Ö; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jan 28; Vol. 27 (3). Date of Electronic Publication: 2022 Jan 28.
Typ publikacji:: Journal Article
MeSH Terms:: Antibiotics, Antitubercular/*pharmacology
Bacterial Proteins/*chemistry
DNA-Directed RNA Polymerases/*chemistry
Mycobacterium tuberculosis/*chemistry
Rifampin/*pharmacology
Bacterial Proteins/genetics ; DNA-Directed RNA Polymerases/genetics ; Drug Resistance, Bacterial ; Humans ; Models, Molecular ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/genetics ; Point Mutation/drug effects ; Tuberculosis/microbiology

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Skocz do pozycji: 2.

Tytuł:: Composition of Transcription Machinery and Its Crosstalk with Nucleoid-Associated Proteins and Global Transcription Factors.
Autorzy:: Muskhelishvili G; School of Natural Sciences, Agricultural University of Georgia, David Aghmashenebeli Alley 24, Tbilisi 0159, Georgia.
Sobetzko P; Department of Chromosome Biology, Philipps-Universität Marburg, LOEWE-Zentrum für Synthetische Mikrobiologie, Hans-Meerwein-Straße, 35043 Marburg, Germany.
Mehandziska S; School of Engineering and Science, Campus Ring 1, Jacobs University Bremen, 28759 Bremen, Germany.
Travers A; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1GA, UK.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2021 Jun 22; Vol. 11 (7). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Gene Expression Regulation, Bacterial*
Transcription, Genetic*
Bacteria/*metabolism
Bacterial Proteins/*metabolism
DNA, Bacterial/*metabolism
DNA-Directed RNA Polymerases/*metabolism
Transcription Factors/*metabolism
Bacteria/genetics ; Bacterial Proteins/genetics ; DNA, Bacterial/genetics ; DNA-Directed RNA Polymerases/genetics ; Transcription Factors/genetics

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Skocz do pozycji: 3.

Tytuł:: Bacterial Regulatory Proteins.
Autorzy:: Kormanec J; Institute of Molecular Biology, Slovak Academy of Sciences, 845 51 Bratislava, Slovakia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jun 20; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 20.
Typ publikacji:: Editorial
MeSH Terms:: Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Gene Expression Regulation, Bacterial*
Bacteria/genetics ; Bacteria/metabolism ; DNA-Directed RNA Polymerases/genetics ; DNA-Directed RNA Polymerases/metabolism ; RNA, Bacterial/genetics ; Transcription Factors/metabolism ; Transcription, Genetic

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Skocz do pozycji: 4.

Tytuł:: The Phage-Encoded N -Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
Autorzy:: Ceyssens PJ; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
De Smet J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Wagemans J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Akulenko N; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Klimuk E; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Hedge S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Voet M; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Hendrix H; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Paeshuyse J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Landuyt B; Department of Biology, KU Leuven, 3000 Leuven, Belgium.
Xu H; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Blanchard J; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Severinov K; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Lavigne R; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Sep 02; Vol. 12 (9). Date of Electronic Publication: 2020 Sep 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetyltransferases/*metabolism
Bacterial Proteins/*metabolism
DNA-Directed RNA Polymerases/*metabolism
Pseudomonas Phages/*enzymology
Pseudomonas aeruginosa/*enzymology
Pseudomonas aeruginosa/*virology
Viral Proteins/*metabolism
Acetyltransferases/genetics ; Bacterial Proteins/genetics ; DNA-Directed RNA Polymerases/genetics ; Host-Pathogen Interactions ; Pseudomonas Phages/genetics ; Pseudomonas aeruginosa/genetics ; Transcription, Genetic ; Viral Proteins/genetics

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Skocz do pozycji: 5.

Tytuł:: Establishment of an in vitro RNA polymerase transcription system: a new tool to study transcriptional activation in Borrelia burgdorferi.
Autorzy:: Boyle WK; Department of Medical Microbiology and Immunology, Creighton University, Omaha, NE, 68105, USA.; Laboratory of Bacteriology, Gene Regulation Section, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, 59840, USA.
Hall LS; Division of Biological Sciences, University of Montana, Missoula, MT, 59812, USA.
Armstrong AA; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Dulebohn DP; Laboratory of Bacteriology, Gene Regulation Section, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, 59840, USA.
Samuels DS; Division of Biological Sciences, University of Montana, Missoula, MT, 59812, USA.
Gherardini FC; Laboratory of Bacteriology, Gene Regulation Section, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, 59840, USA.
Bourret TJ; Department of Medical Microbiology and Immunology, Creighton University, Omaha, NE, 68105, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 May 19; Vol. 10 (1), pp. 8246. Date of Electronic Publication: 2020 May 19.
Typ publikacji:: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Transcriptional Activation*
Bacterial Proteins/*metabolism
Borrelia burgdorferi/*genetics
DNA-Directed RNA Polymerases/*metabolism
Enzyme Assays/*methods
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Borrelia burgdorferi/enzymology ; Borrelia burgdorferi/metabolism ; DNA-Directed RNA Polymerases/chemistry ; DNA-Directed RNA Polymerases/genetics ; Enzyme Stability ; Gene Expression Regulation, Bacterial ; Hydrogen-Ion Concentration ; Promoter Regions, Genetic ; Sigma Factor/genetics ; Sigma Factor/metabolism

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Skocz do pozycji: 6.

Tytuł:: Identification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India.
Autorzy:: Munir A; Department of Biochemistry, University of Cambridge, Tennis Court. Rd., Cambridge, CB2 1GA, UK.
Kumar N; Department of Medicine, University of Cambridge, Hills Rd., Cambridge, CB2 0QQ, UK.
Ramalingam SB; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Tamilzhalagan S; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Shanmugam SK; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Palaniappan AN; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Nair D; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Priyadarshini P; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Natarajan M; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Tripathy S; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Ranganathan UD; ICMR-National Institute for Research in Tuberculosis, Chennai, 600031, India.
Peacock SJ; Department of Medicine, University of Cambridge, Hills Rd., Cambridge, CB2 0QQ, UK.; London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Parkhill J; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
Blundell TL; Department of Biochemistry, University of Cambridge, Tennis Court. Rd., Cambridge, CB2 1GA, UK. .
Malhotra S; Department of Biochemistry, University of Cambridge, Tennis Court. Rd., Cambridge, CB2 1GA, UK. .; Birkbeck College, University of London, Malet Street, WC1E7HX, London, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Jul 16; Vol. 9 (1), pp. 10283. Date of Electronic Publication: 2019 Jul 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Resistance, Bacterial*
Antitubercular Agents/*pharmacology
Bacterial Proteins/*genetics
Catalase/*genetics
DNA-Directed RNA Polymerases/*genetics
Mycobacterium tuberculosis/*genetics
Tuberculosis/*microbiology
Adult ; Allosteric Regulation/drug effects ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Catalase/chemistry ; Catalase/metabolism ; DNA-Directed RNA Polymerases/chemistry ; DNA-Directed RNA Polymerases/metabolism ; Humans ; India ; Isoniazid/pharmacology ; Machine Learning ; Models, Molecular ; Mutation ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/growth & development ; Protein Conformation ; Protein Stability/drug effects ; Rifampin/pharmacology ; Tuberculosis/drug therapy ; Whole Genome Sequencing

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Skocz do pozycji: 7.

Tytuł:: Evaluation of GenoType MTBDRplus for the detection of drug-resistant Mycobacterium tuberculosis on isolates from Karachi, Pakistan.
Autorzy:: Siddiqui S; Global Health Directorate, Indus Health Network, Karachi, Sindh, Pakistan.
Brooks MB; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, United States of America.
Malik AA; Global Health Directorate, Indus Health Network, Karachi, Sindh, Pakistan.; Interactive Research and Development, Karachi, Sindh, Pakistan.; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, United States of America.
Fuad J; Global Health Directorate, Indus Health Network, Karachi, Sindh, Pakistan.
Nazish A; Global Health Directorate, Indus Health Network, Karachi, Sindh, Pakistan.
Bano S; Indus Hospital-TB Laboratory, Indus Health Network, Karachi, Sindh, Pakistan.
Becerra MC; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, United States of America.
Hussain H; Interactive Research and Development, Karachi, Sindh, Pakistan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Aug 19; Vol. 14 (8), pp. e0221485. Date of Electronic Publication: 2019 Aug 19 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genotype*
Mutation*
Bacterial Proteins/*genetics
DNA-Directed RNA Polymerases/*genetics
Mycobacterium tuberculosis/*genetics
Tuberculosis, Multidrug-Resistant/*genetics
Antitubercular Agents/pharmacology ; Bacterial Proteins/metabolism ; DNA-Directed RNA Polymerases/metabolism ; Humans ; Isoniazid/pharmacology ; Male ; Microbial Sensitivity Tests ; Mycobacterium tuberculosis/isolation & purification ; Mycobacterium tuberculosis/metabolism ; Pakistan ; Rifampin/pharmacology ; Tuberculosis, Multidrug-Resistant/metabolism

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Skocz do pozycji: 8.

Tytuł:: Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance.
Autorzy:: Torrea G; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium. .
Ng KCS; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Van Deun A; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
André E; Laboratory of Clinical Bacteriology and Mycology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
Kaisergruber J; Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Ssengooba W; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; Department of Medical Microbiology, College of Health Sciences Makerere University, Kampala, Uganda.
Desmaretz C; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Gabriels S; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Driesen M; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Diels M; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Asnong S; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Fissette K; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Gumusboga M; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Rigouts L; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Affolabi D; Tuberculosis National Reference Laboratory, Cotonou, Benin.
Joloba M; Department of Medical Microbiology, College of Health Sciences Makerere University, Kampala, Uganda.
De Jong BC; Mycobacteriology Unit, Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Aug 14; Vol. 9 (1), pp. 11826. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mutation*
Bacterial Proteins/*genetics
DNA-Directed RNA Polymerases/*genetics
Drug Resistance, Bacterial/*genetics
Mycobacterium tuberculosis/*genetics
Rifampin/*pharmacology
Antitubercular Agents ; Bacterial Proteins/drug effects ; DNA-Directed RNA Polymerases/drug effects ; Genes, Bacterial ; Genotype ; Microbial Sensitivity Tests ; Mycobacterium tuberculosis/drug effects

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Skocz do pozycji: 9.

Tytuł:: Early detection of MDR Mycobacterium tuberculosis mutations in Pakistan.
Autorzy:: Aftab A; Division of Molecular Virology and Infectious Diseases, Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, 87-West Canal Bank Road, Thokar Niaz Baig, Lahore, Pakistan.
Afzal S; Division of Molecular Virology and Infectious Diseases, Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, 87-West Canal Bank Road, Thokar Niaz Baig, Lahore, Pakistan. .
Qamar Z; Division of Molecular Virology and Infectious Diseases, Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, 87-West Canal Bank Road, Thokar Niaz Baig, Lahore, Pakistan.
Idrees M; Division of Molecular Virology and Infectious Diseases, Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, 87-West Canal Bank Road, Thokar Niaz Baig, Lahore, Pakistan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Aug 18; Vol. 11 (1), pp. 16736. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Bacterial Proteins/*genetics
DNA-Directed RNA Polymerases/*genetics
Drug Resistance, Multiple, Bacterial/*genetics
Mycobacterium tuberculosis/*genetics
Tuberculosis, Multidrug-Resistant/*genetics
Humans ; Mycobacterium tuberculosis/isolation & purification ; Pakistan

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Skocz do pozycji: 10.

Tytuł:: Bacillus subtilis PcrA Helicase Removes Trafficking Barriers.
Autorzy:: Moreno-Del Álamo M; Department of Microbial Biotechnology, Centro Nacional de Biotecnología, CNB-CSIC, 28049 Madrid, Spain.
Carrasco B; Department of Microbial Biotechnology, Centro Nacional de Biotecnología, CNB-CSIC, 28049 Madrid, Spain.
Torres R; Department of Microbial Biotechnology, Centro Nacional de Biotecnología, CNB-CSIC, 28049 Madrid, Spain.
Alonso JC; Department of Microbial Biotechnology, Centro Nacional de Biotecnología, CNB-CSIC, 28049 Madrid, Spain.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Apr 17; Vol. 10 (4). Date of Electronic Publication: 2021 Apr 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacillus subtilis/*enzymology
Bacterial Proteins/*metabolism
DNA Helicases/*metabolism
Adenosine Triphosphatases/metabolism ; Bacillus subtilis/metabolism ; Bacterial Proteins/genetics ; Chromosome Segregation ; DNA Helicases/genetics ; DNA Replication ; DNA, Bacterial/metabolism ; DNA-Directed RNA Polymerases/metabolism ; Models, Biological ; Mutation/genetics ; Protein Binding ; Protein Transport ; RNA, Bacterial/metabolism ; Stress, Physiological ; Synthetic Lethal Mutations

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Skocz do pozycji: 11.

Tytuł:: MSMEG_6292, a Mycobacterium smegmatis RNA polymerase secondary channel-binding protein: purification, crystallization and X-ray diffraction analysis.
Autorzy:: Joseph A; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Trivandrum, Kerala 695 016, India.
Nagaraja V; Microbiology and Cell Biology Unit, Indian Institute of Science, Bangalore, Karnataka, India.
Natesh R; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Trivandrum, Kerala 695 016, India.; Pokaż więcej
Źródło:: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2018 Sep 01; Vol. 74 (Pt 9), pp. 543-548. Date of Electronic Publication: 2018 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Bacterial Proteins/*chemistry
DNA-Directed RNA Polymerases/*chemistry
Mycobacterium smegmatis/*chemistry
Peptide Elongation Factors/*chemistry
Amino Acid Sequence ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cloning, Molecular ; Crystallization ; Crystallography, X-Ray ; DNA-Directed RNA Polymerases/genetics ; DNA-Directed RNA Polymerases/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Peptide Elongation Factors/genetics ; Peptide Elongation Factors/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism

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Skocz do pozycji: 12.

Tytuł:: The alternative sigma factor RpoQ regulates colony morphology, biofilm formation and motility in the fish pathogen Aliivibrio salmonicida.
Autorzy:: Khider M; Norwegian Structural Biology Center and the Department of Chemistry, Faculty of Science and Technology, UiT-The Arctic University of Norway, N-9037, Tromsø, Norway.
Willassen NP; Norwegian Structural Biology Center and the Department of Chemistry, Faculty of Science and Technology, UiT-The Arctic University of Norway, N-9037, Tromsø, Norway.
Hansen H; Norwegian Structural Biology Center and the Department of Chemistry, Faculty of Science and Technology, UiT-The Arctic University of Norway, N-9037, Tromsø, Norway. .; Pokaż więcej
Źródło:: BMC microbiology [BMC Microbiol] 2018 Sep 12; Vol. 18 (1), pp. 116. Date of Electronic Publication: 2018 Sep 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Biofilms*
Aliivibrio salmonicida/*growth & development
Aliivibrio salmonicida/*physiology
Bacterial Proteins/*metabolism
DNA-Directed RNA Polymerases/*metabolism
Fish Diseases/*microbiology
Sigma Factor/*metabolism
Aliivibrio salmonicida/cytology ; Aliivibrio salmonicida/genetics ; Animals ; Bacterial Proteins/genetics ; DNA-Directed RNA Polymerases/genetics ; Fishes ; Gene Expression Regulation, Bacterial ; Sigma Factor/genetics

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Skocz do pozycji: 13.

Tytuł:: Correlation of drug resistance with single nucleotide variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of M. tuberculosis.
Autorzy:: Bhattacharyya K; Dr. B. R. Ambedkar Center for Biomedical Research (ACBR), University of Delhi, 110007, New Delhi, India.; Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India.
Nemaysh V; Department of Chemistry, University of Delhi, New Delhi, India.
Joon M; Dr. B. R. Ambedkar Center for Biomedical Research (ACBR), University of Delhi, 110007, New Delhi, India.
Pratap R; Department of Chemistry, University of Delhi, New Delhi, India.
Varma-Basil M; Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India.
Bose M; Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India.
Brahmachari V; Dr. B. R. Ambedkar Center for Biomedical Research (ACBR), University of Delhi, 110007, New Delhi, India. .; Pokaż więcej
Źródło:: BMC microbiology [BMC Microbiol] 2020 Jul 25; Vol. 20 (1), pp. 223. Date of Electronic Publication: 2020 Jul 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Resistance, Multiple, Bacterial*
Polymorphism, Single Nucleotide*
Bacterial Proteins/*genetics
Mycobacterium tuberculosis/*genetics
Tuberculosis/*microbiology
Whole Genome Sequencing/*methods
Antitubercular Agents/pharmacology ; Bacterial Proteins/chemistry ; Binding Sites ; DNA-Directed RNA Polymerases/chemistry ; DNA-Directed RNA Polymerases/genetics ; Gene Expression Regulation, Bacterial ; High-Throughput Nucleotide Sequencing ; Humans ; Models, Molecular ; Molecular Docking Simulation ; Mycobacterium tuberculosis/classification ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/isolation & purification ; Pentosyltransferases/genetics ; Protein Structure, Tertiary ; Rifampin/pharmacology

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Skocz do pozycji: 14.

Tytuł:: Evaluation of the performance of an in-house duplex PCR assay targeting the IS6110 and rpoB genes for tuberculosis diagnosis in Cameroon.
Autorzy:: Meriki HD; Tuberculosis Diagnostic Unit, Buea Regional Hospital, Buea, Cameroon. .; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon. .
Wung NH; Department of Biochemistry and Molecular Biology, University of Buea, Buea, Cameroon.
Tufon KA; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Tony NJ; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Ane-Anyangwe I; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Cho-Ngwa F; Department of Biochemistry and Molecular Biology, University of Buea, Buea, Cameroon.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2020 Oct 23; Vol. 20 (1), pp. 791. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji:: Evaluation Study; Journal Article
MeSH Terms:: Genes, Bacterial*
Bacterial Proteins/*genetics
DNA-Directed RNA Polymerases/*genetics
Mycobacterium tuberculosis/*genetics
Polymerase Chain Reaction/*methods
Tuberculosis, Pulmonary/*diagnosis
Tuberculosis, Pulmonary/*epidemiology
AIDS-Related Opportunistic Infections/diagnosis ; AIDS-Related Opportunistic Infections/virology ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cameroon/epidemiology ; Child ; Child, Preschool ; Cross-Sectional Studies ; DNA Primers ; Female ; HIV ; Humans ; Male ; Microscopy ; Middle Aged ; Mycobacterium tuberculosis/isolation & purification ; Sensitivity and Specificity ; Sputum/microbiology ; Tuberculosis, Pulmonary/microbiology ; Young Adult

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Skocz do pozycji: 15.

Tytuł:: Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes.
Autorzy:: Gupta A; Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India.; Division of Molecular Biology, National AIDS Research Institute, 73 G MIDC Bhosari, Pune, 411026, India.
Sinha P; Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India.
Nema V; Division of Molecular Biology, National AIDS Research Institute, 73 G MIDC Bhosari, Pune, 411026, India.
Gupta PK; Laboratory Nuclear Medicine Section, Isotope Group, Bhabha Atomic Research Centre C/o T.M.H. Annexe, Parel, Mumbai, 400012, India.
Chakraborty P; Laboratory Nuclear Medicine Section, Isotope Group, Bhabha Atomic Research Centre C/o T.M.H. Annexe, Parel, Mumbai, 400012, India.
Kulkarni S; Laboratory Nuclear Medicine Section, Isotope Group, Bhabha Atomic Research Centre C/o T.M.H. Annexe, Parel, Mumbai, 400012, India.
Rastogi N; WHO Supranational TB Reference Laboratory, TB & Mycobacteria Unit, Institute Pasteur de Guadeloupe, Abymes, Guadeloupe, France.
Anupurba S; Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India. shampa_.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2020 Oct 14; Vol. 20 (1), pp. 752. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji:: Journal Article
MeSH Terms:: Bacterial Proteins/*genetics
Catalase/*genetics
DNA-Directed RNA Polymerases/*genetics
Mycobacterium tuberculosis/*genetics
Pentosyltransferases/*genetics
Tuberculosis, Multidrug-Resistant/*microbiology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antitubercular Agents/pharmacology ; Child ; Drug Resistance, Multiple, Bacterial/drug effects ; Drug Resistance, Multiple, Bacterial/genetics ; Female ; Genotype ; Humans ; India/epidemiology ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Multiplex Polymerase Chain Reaction/methods ; Mutation Rate ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/isolation & purification ; Tuberculosis, Multidrug-Resistant/epidemiology ; Young Adult

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Skocz do pozycji: 16.

Tytuł:: Identification and characterization of mutations responsible for the β-lactam resistance in oxacillin-susceptible mecA-positive Staphylococcus aureus.
Autorzy:: Boonsiri T; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Watanabe S; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Tan XE; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Thitiananpakorn K; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Narimatsu R; School of Medicine, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Sasaki K; School of Medicine, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Takenouchi R; School of Medicine, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Sato'o Y; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Aiba Y; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Kiga K; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Sasahara T; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Taki Y; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Li FY; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Zhang Y; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Azam AH; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Kawaguchi T; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Cui L; Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Oct 09; Vol. 10 (1), pp. 16907. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*genetics
Mutation/*genetics
Oxacillin/*pharmacology
Staphylococcus aureus/*drug effects
Staphylococcus aureus/*genetics
beta-Lactam Resistance/*genetics
Anti-Bacterial Agents/pharmacology ; DNA-Directed RNA Polymerases/genetics ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Gene Expression Regulation, Bacterial/drug effects ; Gene Expression Regulation, Bacterial/genetics ; Genome/genetics ; Genome-Wide Association Study/methods ; Humans ; Microbial Sensitivity Tests/methods ; Phylogeny ; Staphylococcal Infections/drug therapy ; Transcription, Genetic/drug effects ; Transcription, Genetic/genetics ; Up-Regulation/drug effects ; Up-Regulation/genetics

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Skocz do pozycji: 17.

Tytuł:: Detection of mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains inhibiting wild type probe hybridization in the MTBDR plus assay by DNA sequencing directly from clinical specimens.
Autorzy:: Sinha P; Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India.
Srivastava GN; Department of Respiratory Diseases, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India. gn_.
Tripathi R; Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India.
Mishra MN; CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, 226015, India.
Anupurba S; Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India. shampa_.; Pokaż więcej
Źródło:: BMC microbiology [BMC Microbiol] 2020 Sep 16; Vol. 20 (1), pp. 284. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*genetics
DNA Mutational Analysis/*methods
DNA-Directed RNA Polymerases/*genetics
Mycobacterium tuberculosis/*drug effects
Mycobacterium tuberculosis/*genetics
Rifampin/*pharmacology
Antibiotics, Antitubercular/pharmacology ; DNA Probes ; Drug Resistance, Bacterial/genetics ; Humans ; In Situ Hybridization ; Mutation ; Mycobacterium tuberculosis/isolation & purification ; Sequence Analysis, DNA/methods ; Sputum/microbiology ; Tuberculosis, Multidrug-Resistant/microbiology ; Tuberculosis, Pulmonary/microbiology

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Skocz do pozycji: 18.

Tytuł:: Novel Escherichia coli RNA Polymerase Binding Protein Encoded by Bacteriophage T5.
Autorzy:: Klimuk E; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.; Skolkovo Institute of Science and Technology, Center of Life Sciences, 121205 Skolkovo, Russia.
Mekler V; Waksman Institute for Microbiology and Department of Molecular Biology and Biochemistry, Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA.
Lavysh D; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Serebryakova M; Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Akulenko N; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Severinov K; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.; Skolkovo Institute of Science and Technology, Center of Life Sciences, 121205 Skolkovo, Russia.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Jul 26; Vol. 12 (8). Date of Electronic Publication: 2020 Jul 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*genetics
Carrier Proteins/*genetics
Coliphages/*genetics
DNA-Directed RNA Polymerases/*genetics
Viral Proteins/*genetics
Carrier Proteins/isolation & purification ; Gene Expression Regulation, Viral ; Protein Binding ; Transcription, Genetic

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Skocz do pozycji: 19.

Tytuł:: Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA Polymerase alterations and fine tuning of gene expression.
Autorzy:: Panchal VV; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.
Griffiths C; Centre for Bacterial Cell Biology, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Mosaei H; Centre for Bacterial Cell Biology, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Bilyk B; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.
Sutton JAF; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.
Carnell OT; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.
Hornby DP; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.
Green J; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.
Hobbs JK; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.; Department of Physics and Astronomy, University of Sheffield, Sheffield, United Kingdom.
Kelley WL; Department of Microbiology and Molecular Medicine, University Hospital and Medical School of Geneva, Geneva, Switzerland.
Zenkin N; Centre for Bacterial Cell Biology, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Foster SJ; Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, United Kingdom.; The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2020 Jul 24; Vol. 16 (7), pp. e1008672. Date of Electronic Publication: 2020 Jul 24 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*genetics
DNA-Directed RNA Polymerases/*genetics
Gene Expression Regulation, Bacterial/*genetics
Methicillin-Resistant Staphylococcus aureus/*genetics
Penicillin-Binding Proteins/*genetics
beta-Lactam Resistance/*genetics
Anti-Bacterial Agents/pharmacology ; Methicillin-Resistant Staphylococcus aureus/drug effects

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Skocz do pozycji: 20.

Tytuł:: A novel gene expression system for Ralstonia eutropha based on the T7 promoter.
Autorzy:: Hu M; School of Biological Engineering, Dalian Polytechnic University, Dalian, 116034, People's Republic of China.; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Xiong B; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Li Z; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Liu L; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Li S; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Zhang C; School of Biological Engineering, Dalian Polytechnic University, Dalian, 116034, People's Republic of China.
Zhang X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China.
Bi C; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China. bi_.; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, People's Republic of China. bi_.; Pokaż więcej
Źródło:: BMC microbiology [BMC Microbiol] 2020 May 19; Vol. 20 (1), pp. 121. Date of Electronic Publication: 2020 May 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*genetics
Cupriavidus necator/*metabolism
DNA-Directed RNA Polymerases/*genetics
Plasmids/*genetics
Viral Proteins/*genetics
Arabinose/metabolism ; Cloning, Molecular ; Cupriavidus necator/genetics ; Electroporation ; Gene Expression Regulation, Bacterial ; Metabolic Engineering ; Polyhydroxyalkanoates/metabolism ; Promoter Regions, Genetic

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