Temat: "DNA-Directed RNA Polymerases" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A big step toward mirror-image ribosomes.
Autorzy:: Service RF; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2022 Oct 28; Vol. 378 (6618), pp. 345-346. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:: Wiadomości
MeSH Terms:: Ribosomes*
DNA-Directed RNA Polymerases*/chemical synthesis
DNA-Directed RNA Polymerases*/chemistry
Viral Proteins*/chemical synthesis
Viral Proteins*/chemistry

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Tytuł:: Dielectricity of a molecularly crowded solution accelerates NTP misincorporation during RNA-dependent RNA polymerization by T7 RNA polymerase.
Autorzy:: Takahashi S; Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan.
Matsumoto S; Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan.
Chilka P; Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan.
Ghosh S; Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan.
Okura H; Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan.
Sugimoto N; Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan. .; Graduate School of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 7-1-20 Minatojima-Minamimachi, Kobe, 650-0047, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 21; Vol. 12 (1), pp. 1149. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA-Directed RNA Polymerases/*chemistry
RNA/*biosynthesis
Viral Proteins/*chemistry
Base Pairing ; DNA-Directed RNA Polymerases/metabolism ; Genetic Variation ; Polymerization ; RNA/genetics ; Ribonucleosides/chemistry ; Ribonucleosides/metabolism ; Solutions ; Substrate Specificity ; Viral Proteins/metabolism

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Skocz do pozycji: 3.

Tytuł:: Method for Rapid Analysis of Mutant RNA Polymerase Activity on Templates Containing Unnatural Nucleotides.
Autorzy:: Egorova T; Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, 119991 Moscow, Russia.
Shuvalova E; Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, 119991 Moscow, Russia.
Mukba S; Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, 119991 Moscow, Russia.
Shuvalov A; Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, 119991 Moscow, Russia.
Kolosov P; Institute of Higher Nervous Activity and Neurophysiology, The Russian Academy of Sciences, 117485 Moscow, Russia.
Alkalaeva E; Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, 119991 Moscow, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 14; Vol. 22 (10). Date of Electronic Publication: 2021 May 14.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Templates, Genetic*
Bacteriophage T7/*enzymology
DNA-Directed RNA Polymerases/*metabolism
Nucleotides/*analysis
Viral Proteins/*metabolism
Cell-Free System ; DNA-Directed RNA Polymerases/genetics ; Transcription, Genetic ; Viral Proteins/genetics

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Skocz do pozycji: 4.

Tytuł:: Development of Monoclonal Antibodies for Detection of Conserved and Variable Epitopes of Large Protein of Rabies Virus.
Autorzy:: Zhao W; Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Su J; Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Zhao N; Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Liu J; Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Su S; Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Jan 31; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Monoclonal/*analysis
DNA-Directed RNA Polymerases/*immunology
Epitopes/*immunology
Rabies/*virology
Rabies virus/*immunology
Viral Proteins/*immunology
Amino Acid Sequence ; Antibodies, Monoclonal/immunology ; DNA-Directed RNA Polymerases/chemistry ; DNA-Directed RNA Polymerases/genetics ; Epitope Mapping ; Epitopes/chemistry ; Epitopes/genetics ; Humans ; Phylogeny ; Rabies virus/chemistry ; Rabies virus/classification ; Rabies virus/genetics ; Sequence Alignment ; Viral Proteins/chemistry ; Viral Proteins/genetics

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Skocz do pozycji: 5.

Tytuł:: The Polarity of an Amino Acid at Position 1891 of Severe Fever with Thrombocytopenia Syndrome Virus L Protein Is Critical for the Polymerase Activity.
Autorzy:: Noda K; School of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Tsuda Y; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Kozawa F; School of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Igarashi M; Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Shimizu K; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Arikawa J; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Yoshimatsu K; Laboratory of Animal Experimentation, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Graduate School of Infectious Diseases, Hokkaido University, Sapporo 060-0815, Japan.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Dec 27; Vol. 13 (1). Date of Electronic Publication: 2020 Dec 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amino Acids*/chemistry
DNA-Directed RNA Polymerases/*metabolism
Phlebovirus/*physiology
Viral Proteins/*metabolism
Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Cell Line ; DNA-Directed RNA Polymerases/chemistry ; DNA-Directed RNA Polymerases/genetics ; Fluorescent Antibody Technique ; Humans ; Models, Molecular ; Protein Conformation ; Severe Fever with Thrombocytopenia Syndrome ; Viral Proteins/chemistry ; Viral Proteins/genetics

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Skocz do pozycji: 6.

Tytuł:: GDP polyribonucleotidyltransferase domain of vesicular stomatitis virus polymerase regulates leader-promoter escape and polyadenylation-coupled termination during stop-start transcription.
Autorzy:: Ogino M; Department of Medical Microbiology and Immunology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America.
Green TJ; Department of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Ogino T; Department of Medical Microbiology and Immunology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2022 Feb 02; Vol. 18 (2), pp. e1010287. Date of Electronic Publication: 2022 Feb 02 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Polyribonucleotide Nucleotidyltransferase/*metabolism
RNA, Viral/*metabolism
RNA-Dependent RNA Polymerase/*genetics
RNA-Dependent RNA Polymerase/*metabolism
Vesicular Stomatitis/*virology
Vesicular stomatitis Indiana virus/*genetics
Vesicular stomatitis Indiana virus/*metabolism
Viral Proteins/*genetics
Viral Proteins/*metabolism
Amino Acid Substitution ; Animals ; Cell Line ; DNA-Directed RNA Polymerases/genetics ; DNA-Directed RNA Polymerases/metabolism ; Mutation ; Nucleotidyltransferases/metabolism ; Polyribonucleotide Nucleotidyltransferase/genetics ; Protein Conformation ; Protein Domains ; RNA Precursors/metabolism ; Transcription, Genetic ; Virus Replication

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Skocz do pozycji: 7.

Tytuł:: Multisubunit RNA Polymerases of Jumbo Bacteriophages.
Autorzy:: Sokolova ML; Center of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
Misovetc I; Center of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
V Severinov K; Waksman Institute of Microbiology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Sep 23; Vol. 12 (10). Date of Electronic Publication: 2020 Sep 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: DNA-Directed RNA Polymerases*/chemistry
DNA-Directed RNA Polymerases*/metabolism
Viral Proteins*/chemistry
Viral Proteins*/metabolism
Bacteriophages/*enzymology
DNA, Single-Stranded/metabolism ; Promoter Regions, Genetic ; Protein Subunits ; Transcription, Genetic

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Skocz do pozycji: 8.

Tytuł:: The Phage-Encoded N -Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
Autorzy:: Ceyssens PJ; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
De Smet J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Wagemans J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Akulenko N; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Klimuk E; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Hedge S; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Voet M; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Hendrix H; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Paeshuyse J; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.
Landuyt B; Department of Biology, KU Leuven, 3000 Leuven, Belgium.
Xu H; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Blanchard J; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10461, USA.
Severinov K; Institute of Molecular Genetics, Russian Academy of Sciences, 119334 Moscow, Russia.
Lavigne R; Department of Biosystems, KU Leuven, 3000 Leuven, Belgium.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Sep 02; Vol. 12 (9). Date of Electronic Publication: 2020 Sep 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetyltransferases/*metabolism
Bacterial Proteins/*metabolism
DNA-Directed RNA Polymerases/*metabolism
Pseudomonas Phages/*enzymology
Pseudomonas aeruginosa/*enzymology
Pseudomonas aeruginosa/*virology
Viral Proteins/*metabolism
Acetyltransferases/genetics ; Bacterial Proteins/genetics ; DNA-Directed RNA Polymerases/genetics ; Host-Pathogen Interactions ; Pseudomonas Phages/genetics ; Pseudomonas aeruginosa/genetics ; Transcription, Genetic ; Viral Proteins/genetics

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Skocz do pozycji: 9.

Tytuł:: The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion.
Autorzy:: Heilmann E; Division of Virology, Medical University of Innsbruck, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Viral Immunotherapy of Cancer, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Kimpel J; Division of Virology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Geley S; Division of Molecular Pathophysiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Naschberger A; Division of Genetic Epidemiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Urbiola C; Division of Virology, Medical University of Innsbruck, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Viral Immunotherapy of Cancer, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Nolden T; ViraTherapeutics GmbH, 6020 Innsbruck, Austria.
von Laer D; Division of Virology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Wollmann G; Division of Virology, Medical University of Innsbruck, 6020 Innsbruck, Austria.; Christian Doppler Laboratory for Viral Immunotherapy of Cancer, Medical University of Innsbruck, 6020 Innsbruck, Austria.; Pokaż więcej
Źródło:: Viruses [Viruses] 2019 Oct 26; Vol. 11 (11). Date of Electronic Publication: 2019 Oct 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA-Directed RNA Polymerases/*genetics
DNA-Directed RNA Polymerases/*metabolism
Vesiculovirus/*enzymology
Viral Proteins/*genetics
Viral Proteins/*metabolism
Cell Line ; DNA-Directed RNA Polymerases/chemistry ; Humans ; Mutagenesis, Insertional ; Rhabdoviridae Infections/virology ; Vesiculovirus/chemistry ; Vesiculovirus/genetics ; Viral Proteins/chemistry

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Skocz do pozycji: 10.

Tytuł:: Toehold-Mediated Strand Displacement in a Triplex Forming Nucleic Acid Clamp for Reversible Regulation of Polymerase Activity and Protein Expression.
Autorzy:: Nguyen TJD; Center for Multifunctional Biomolecular Drug Design (CEMBID) at the, Interdisciplinary Nanoscience Center (iNANO) and the Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark.
Manuguerra I; Center for Multifunctional Biomolecular Drug Design (CEMBID) at the, Interdisciplinary Nanoscience Center (iNANO) and the Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark.
Kumar V; Center for Multifunctional Biomolecular Drug Design (CEMBID) at the, Interdisciplinary Nanoscience Center (iNANO) and the Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark.
Gothelf KV; Center for Multifunctional Biomolecular Drug Design (CEMBID) at the, Interdisciplinary Nanoscience Center (iNANO) and the Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark.; Pokaż więcej
Źródło:: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2019 Sep 20; Vol. 25 (53), pp. 12303-12307. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: DNA/*chemistry
DNA-Directed RNA Polymerases/*chemistry
Nucleic Acids/*chemistry
RNA/*chemistry
Viral Proteins/*chemistry
Amino Alcohols/chemistry ; Butylene Glycols/chemistry ; DNA-Directed RNA Polymerases/metabolism ; DNA-Directed RNA Polymerases/pharmacology ; Viral Proteins/metabolism ; Viral Proteins/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Transcriptional Control and mRNA Capping by the GDP Polyribonucleotidyltransferase Domain of the Rabies Virus Large Protein.
Autorzy:: Ogino T; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. .; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. .
Green TJ; Department of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2019 Jun 01; Vol. 11 (6). Date of Electronic Publication: 2019 Jun 01.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: DNA-Directed RNA Polymerases*/genetics
DNA-Directed RNA Polymerases*/metabolism
Rabies virus*/chemistry
Rabies virus*/genetics
Rabies virus*/metabolism
Transcription, Genetic*
Viral Proteins*/genetics
Viral Proteins*/metabolism
Virus Replication*
RNA Caps/*metabolism
Animals ; Gene Expression Regulation ; Genome, Viral ; Humans ; Polyribonucleotide Nucleotidyltransferase/genetics ; Polyribonucleotide Nucleotidyltransferase/metabolism ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Rhabdoviridae/genetics ; Rhabdoviridae/metabolism

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Skocz do pozycji: 12.

Tytuł:: One-Pot Production of RNA in High Yield and Purity Through Cleaving Tandem Transcripts.
Autorzy:: Feyrer H; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Munteanu R; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Baronti L; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Petzold K; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2020 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: DNA-Directed RNA Polymerases/*metabolism
RNA/*metabolism
Ribonuclease H/*genetics
Tandem Repeat Sequences/*genetics
Viral Proteins/*metabolism
DNA-Directed RNA Polymerases/genetics ; RNA/genetics ; Transcription, Genetic/genetics ; Viral Proteins/genetics

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Skocz do pozycji: 13.

Tytuł:: Regulating the T7 RNA polymerase expression in E. coli BL21 (DE3) to provide more host options for recombinant protein production.
Autorzy:: Du F; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, People's Republic of China.
Liu YQ; Nanjing Foreign Language School, Nanjing, People's Republic of China.
Xu YS; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, People's Republic of China.
Li ZJ; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, People's Republic of China.
Wang YZ; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, People's Republic of China.
Zhang ZX; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, People's Republic of China.
Sun XM; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, People's Republic of China. .; Pokaż więcej
Źródło:: Microbial cell factories [Microb Cell Fact] 2021 Sep 26; Vol. 20 (1), pp. 189. Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Bacterial*
Cloning, Molecular/*methods
DNA-Directed RNA Polymerases/*genetics
Escherichia coli/*genetics
Recombinant Proteins/*biosynthesis
Viral Proteins/*genetics
Genetic Vectors ; Membrane Transport Proteins/genetics ; Protein Transport ; Recombinant Proteins/genetics

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Skocz do pozycji: 14.

Tytuł:: Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions.
Autorzy:: Webby MN; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand.; Department of Biochemistry, University of Oxford, Oxford OX1 2JD, UK.
Herr N; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand.
Bulloch EMM; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand.
Schmitz M; School of Chemical Sciences, University of Auckland, Auckland 1010, New Zealand.
Keown JR; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand.; Division of Structural Biology, University of Oxford, Oxford OX1 2JD, UK.
Goldstone DC; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand.
Kingston RL; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Aug 31; Vol. 13 (9). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Paramyxoviridae/*metabolism
Phosphoproteins/*chemistry
Viral Proteins/*chemistry
Catalytic Domain ; Crystallography, X-Ray ; DNA-Directed RNA Polymerases ; Models, Molecular ; Paramyxoviridae/genetics ; Phosphoproteins/genetics ; Protein Binding ; Protein Domains ; RNA, Viral ; Viral Proteins/genetics

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Skocz do pozycji: 15.

Tytuł:: Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts.
Autorzy:: Braun MR; Department of Microbiology, Boston University School of Medicine; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, United States of America.
Noton SL; Department of Microbiology, Boston University School of Medicine; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, United States of America.
Blanchard EL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, United States of America.
Shareef A; Department of Microbiology, Boston University School of Medicine; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, United States of America.
Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, United States of America.
Johnson WE; Division of Computational Biomedicine and Bioinformatics Program and Department of Biostatistics, Boston University, Boston, Massachusetts, United States of America.
Fearns R; Department of Microbiology, Boston University School of Medicine; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 May 18; Vol. 17 (5), pp. e1009589. Date of Electronic Publication: 2021 May 18 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: RNA, Messenger/*metabolism
Respiratory Syncytial Virus Infections/*virology
Respiratory Syncytial Virus, Human/*genetics
Viral Proteins/*metabolism
DNA-Directed RNA Polymerases/genetics ; DNA-Directed RNA Polymerases/metabolism ; Humans ; RNA, Messenger/genetics ; RNA-Binding Proteins ; Transcriptional Elongation Factors/genetics ; Transcriptional Elongation Factors/metabolism ; Viral Proteins/genetics ; Virus Replication

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Skocz do pozycji: 16.

Tytuł:: DeepEMhancer: a deep learning solution for cryo-EM volume post-processing.
Autorzy:: Sanchez-Garcia R; Biocomputing Unit, Centro Nacional de Biotecnología-CSIC, Madrid, Spain.; Department of Statistics, University of Oxford, Oxford, UK.
Gomez-Blanco J; Department of Anatomy and Cell Biology, McGill University, Montréal, QC, Canada.; Departamento de Óptica, Universidad Complutense de Madrid, Madrid, Spain.
Cuervo A; Biocomputing Unit, Centro Nacional de Biotecnología-CSIC, Madrid, Spain.
Carazo JM; Biocomputing Unit, Centro Nacional de Biotecnología-CSIC, Madrid, Spain.
Sorzano COS; Biocomputing Unit, Centro Nacional de Biotecnología-CSIC, Madrid, Spain. .
Vargas J; Department of Anatomy and Cell Biology, McGill University, Montréal, QC, Canada. .; Departamento de Óptica, Universidad Complutense de Madrid, Madrid, Spain. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Jul 15; Vol. 4 (1), pp. 874. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Deep Learning*
Cryoelectron Microscopy/*instrumentation
DNA-Directed RNA Polymerases/*ultrastructure
SARS-CoV-2/*ultrastructure
Viral Proteins/*ultrastructure

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Skocz do pozycji: 17.

Tytuł:: A T7 autogene-based hybrid mRNA/DNA system for long-term shRNA expression in cytoplasm without inefficient nuclear entry.
Autorzy:: Kwak SY; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea.
Han HD; Department of Immunology, School of Medicine, Konkuk University, Chungju, South Korea.
Ahn HJ; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Feb 28; Vol. 9 (1), pp. 2993. Date of Electronic Publication: 2019 Feb 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Transfer Techniques*
DNA-Directed RNA Polymerases/*genetics
Neoplasms, Experimental/*therapy
RNA, Small Interfering/*genetics
RNAi Therapeutics/*methods
Viral Proteins/*genetics
Animals ; Cell Line, Tumor ; Cytoplasm/metabolism ; DNA/genetics ; DNA/metabolism ; DNA-Directed RNA Polymerases/metabolism ; Female ; Liposomes/chemistry ; Mice ; Mice, Inbred BALB C ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Viral Proteins/metabolism

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Skocz do pozycji: 18.

Tytuł:: Construction of a new T7 promoter compatible Escherichia coli Nissle 1917 strain for recombinant production of heme-dependent proteins.
Autorzy:: Fiege K; Fachbereich Biologie, Abt. Mikrobiologie, Technische Universität Kaiserslautern, Paul-Ehrlich-Str. 23, 67663, Kaiserslautern, Germany.
Frankenberg-Dinkel N; Fachbereich Biologie, Abt. Mikrobiologie, Technische Universität Kaiserslautern, Paul-Ehrlich-Str. 23, 67663, Kaiserslautern, Germany. .; Pokaż więcej
Źródło:: Microbial cell factories [Microb Cell Fact] 2020 Oct 06; Vol. 19 (1), pp. 190. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Promoter Regions, Genetic*
DNA-Directed RNA Polymerases/*genetics
Escherichia coli/*genetics
Escherichia coli/*metabolism
Hemeproteins/*biosynthesis
Viral Proteins/*genetics
Bacterial Outer Membrane Proteins/genetics ; Escherichia coli Proteins/genetics ; Genetic Engineering ; Heme/metabolism ; Probiotics/metabolism ; Receptors, Cell Surface/genetics ; Recombinant Proteins/biosynthesis

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Skocz do pozycji: 19.

Tytuł:: Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.
Autorzy:: Jordan PC; Alios BioPharma, Inc. a Janssen Pharmaceutical Company of Johnson & Johnson, South San Francisco, California, United States of America.
Liu C; Alios BioPharma, Inc. a Janssen Pharmaceutical Company of Johnson & Johnson, South San Francisco, California, United States of America.
Raynaud P; Alios BioPharma, Inc. a Janssen Pharmaceutical Company of Johnson & Johnson, South San Francisco, California, United States of America.
Lo MK; Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Spiropoulou CF; Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Symons JA; Alios BioPharma, Inc. a Janssen Pharmaceutical Company of Johnson & Johnson, South San Francisco, California, United States of America.
Beigelman L; Alios BioPharma, Inc. a Janssen Pharmaceutical Company of Johnson & Johnson, South San Francisco, California, United States of America.
Deval J; Alios BioPharma, Inc. a Janssen Pharmaceutical Company of Johnson & Johnson, South San Francisco, California, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2018 Feb 09; Vol. 14 (2), pp. e1006889. Date of Electronic Publication: 2018 Feb 09 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcription Elongation, Genetic*
Transcription Initiation, Genetic*
Transcription Termination, Genetic*
DNA-Directed RNA Polymerases/*metabolism
Nipah Virus/*genetics
Phosphoproteins/*metabolism
Viral Proteins/*metabolism
Amino Acid Sequence ; DNA-Directed RNA Polymerases/chemistry ; DNA-Directed RNA Polymerases/genetics ; Nipah Virus/enzymology ; Paramyxovirinae/enzymology ; Paramyxovirinae/genetics ; Paramyxovirinae/metabolism ; Phosphoproteins/chemistry ; Phosphoproteins/genetics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Viral Proteins/chemistry ; Viral Proteins/genetics ; Virus Replication

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Skocz do pozycji: 20.

Tytuł:: Novel Escherichia coli RNA Polymerase Binding Protein Encoded by Bacteriophage T5.
Autorzy:: Klimuk E; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.; Skolkovo Institute of Science and Technology, Center of Life Sciences, 121205 Skolkovo, Russia.
Mekler V; Waksman Institute for Microbiology and Department of Molecular Biology and Biochemistry, Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA.
Lavysh D; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Serebryakova M; Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Akulenko N; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Severinov K; Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.; Skolkovo Institute of Science and Technology, Center of Life Sciences, 121205 Skolkovo, Russia.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Jul 26; Vol. 12 (8). Date of Electronic Publication: 2020 Jul 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*genetics
Carrier Proteins/*genetics
Coliphages/*genetics
DNA-Directed RNA Polymerases/*genetics
Viral Proteins/*genetics
Carrier Proteins/isolation & purification ; Gene Expression Regulation, Viral ; Protein Binding ; Transcription, Genetic

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