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Tytuł:
Amphetamine pretreatment blunts dopamine-induced D2/D3-receptor occupancy by an arrestin-mediated mechanism: A PET study in internalization compromised mice.
Autorzy:
Mandeville JB; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: .
Weigand-Whittier J; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA; Department of Bioengineering, University of California, Berkeley, CA, USA.
Wey HY; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Chen YI; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
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Źródło:
NeuroImage [Neuroimage] 2023 Dec 01; Vol. 283, pp. 120416. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Dopamine D3*/metabolism
Dopamine*/metabolism
Mice ; Animals ; Raclopride/pharmacology ; Raclopride/metabolism ; Dopamine Antagonists ; Arrestin/metabolism ; Positron-Emission Tomography/methods ; Dopamine Agonists/pharmacology ; Amphetamines ; Amphetamine/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Association of protein distribution and gene expression revealed by positron emission tomography and postmortem gene expression in the dopaminergic system of the human brain.
Autorzy:
Yamamoto Y; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan.
Takahata K; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan. .
Kubota M; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.; Department of Psychiatry, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Takeuchi H; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan.
Moriguchi S; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
Sasaki T; Department of Psychiatry, Tokyo Metropolitan Bokutoh Hospital, 4-23-15 Kotobashi, Sumida-Ku, Tokyo, 130-8575, Japan.
Seki C; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
Endo H; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
Matsuoka K; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
Tagai K; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
Kimura Y; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi, 474-8511, Japan.
Kurose S; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
Mimura M; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan.
Kawamura K; Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, Chiba, 263-8555, Japan.
Zhang MR; Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, Chiba, 263-8555, Japan.
Higuchi M; Department of Functional Brain Imaging, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.
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Źródło:
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 Nov; Vol. 50 (13), pp. 3928-3936. Date of Electronic Publication: 2023 Aug 15.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*/metabolism
Brain*/diagnostic imaging
Brain*/metabolism
Humans ; Positron-Emission Tomography/methods ; Receptors, Dopamine D2/genetics ; Receptors, Dopamine D2/metabolism ; Receptors, Dopamine D3/genetics ; Receptors, Dopamine D3/metabolism ; Dopamine Plasma Membrane Transport Proteins/genetics ; Dopamine Plasma Membrane Transport Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Gene Expression
Czasopismo naukowe
Szczegóły
Tytuł:
Sex-Specific and Traumatic Brain Injury Effects on Dopamine Receptor Expression in the Hippocampus.
Autorzy:
Iannucci J; Department of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, TX 77807, USA.
O'Neill K; Department of Biological Science, Texas A&M University, College Station, TX 77843, USA.
Wang X; Department of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, TX 77807, USA.
Mukherjee S; Department of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, TX 77807, USA.
Wang J; Department of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, TX 77807, USA.
Shapiro LA; Department of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, TX 77807, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 08; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*/metabolism
Brain Injuries, Traumatic*/metabolism
Female ; Male ; Mice ; Animals ; Hippocampus/metabolism ; Neurons/metabolism ; Receptors, Dopamine D2/genetics ; Receptors, Dopamine D2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of behavioral changes in T-maze alternation from dopamine D 1 agonists with different receptor coupling mechanisms.
Autorzy:
Cimino JX; Neuroscience Program, Penn State University College of Medicine, Hershey, PA, 17033, USA.
Zhou M; Department of Pharmacology, Penn State University College of Medicine, Hershey, PA, 17033, USA.; Department of Neurology, Penn State University College of Medicine, Hershey, PA, 17033, USA.
Waxmonsky J; Department of Psychiatry and Behavioral Health, Penn State University College of Medicine, Hershey, PA, 17033, USA.
Mailman RB; Department of Pharmacology, Penn State University College of Medicine, Hershey, PA, 17033, USA.; Department of Neurology, Penn State University College of Medicine, Hershey, PA, 17033, USA.
Yang Y; Department of Pharmacology, Penn State University College of Medicine, Hershey, PA, 17033, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Oct; Vol. 240 (10), pp. 2187-2199. Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine Agonists*/pharmacology
Dopamine*/pharmacology
Ligands ; Receptors, Dopamine D1/metabolism ; Maze Learning ; beta-Arrestins/metabolism ; beta-Arrestins/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Arrestin-3 Agonism at Dopamine D 3 Receptors Defines a Subclass of Second-Generation Antipsychotics That Promotes Drug Tolerance.
Autorzy:
Schamiloglu S; Neuroscience Graduate Program, University of California San Francisco, San Francisco, California.
Lewis E; Neuroscience Graduate Group, University of California Davis, Davis, California; Center for Neuroscience, University of California Davis, Davis, California.
Keeshen CM; Neuroscience Graduate Group, University of California Davis, Davis, California; Center for Neuroscience, University of California Davis, Davis, California.
Hergarden AC; Center for Neuroscience, University of California Davis, Davis, California.
Bender KJ; Neuroscience Graduate Program, University of California San Francisco, San Francisco, California; Department of Neurology, Kavli Institute for Fundamental Neuroscience, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, California. Electronic address: .
Whistler JL; Center for Neuroscience, University of California Davis, Davis, California; Department of Physiology and Membrane Biology, University of California Davis School of Medicine, Davis, California. Electronic address: .
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Źródło:
Biological psychiatry [Biol Psychiatry] 2023 Oct 01; Vol. 94 (7), pp. 531-542. Date of Electronic Publication: 2023 Mar 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Dopamine*
Antipsychotic Agents*/pharmacology
Mice ; Animals ; beta-Arrestin 2/metabolism ; Receptors, Dopamine D3/metabolism ; Dopamine Agonists/pharmacology ; Drug Tolerance ; Receptors, Dopamine D1/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Dopamine receptor activation regulates reward expectancy signals during cognitive control in primate prefrontal neurons.
Autorzy:
Ott T; Animal Physiology, Institute of Neurobiology, Auf der Morgenstelle 28, University of Tübingen, 72076, Tübingen, Germany. .; Bernstein Center for Computational Neuroscience and Institute of Biology, Humboldt-University of Berlin, 10099, Berlin, Germany. .
Stein AM; Animal Physiology, Institute of Neurobiology, Auf der Morgenstelle 28, University of Tübingen, 72076, Tübingen, Germany.
Nieder A; Animal Physiology, Institute of Neurobiology, Auf der Morgenstelle 28, University of Tübingen, 72076, Tübingen, Germany. .
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Źródło:
Nature communications [Nat Commun] 2023 Nov 20; Vol. 14 (1), pp. 7537. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*
Receptors, Dopamine D1*/metabolism
Humans ; Animals ; Male ; Prefrontal Cortex/physiology ; Primates ; Cognition/physiology ; Receptors, Dopamine D2/metabolism ; Dopaminergic Neurons/metabolism ; Macaca/metabolism ; Reward
Czasopismo naukowe
Szczegóły
Tytuł:
The Dopaminergic System Modulates the Electrophysiological Activity of the Suprachiasmatic Nucleus Dependent on the Circadian Cycle.
Autorzy:
Mesgar S; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, P.O.Box: 19615-1178, Tehran, Iran.; Biology and Anatomical Sciences Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Eskandari K; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, P.O.Box: 19615-1178, Tehran, Iran.
Karimian-Sani-Varjovi H; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, P.O.Box: 19615-1178, Tehran, Iran.
Salemi-Mokri-Boukani P; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, P.O.Box: 19615-1178, Tehran, Iran.
Haghparast A; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, P.O.Box: 19615-1178, Tehran, Iran. .; School of Cognitive Sciences, Institute for Research in Fundamental Sciences, Tehran, Iran. .; Department of Basic Sciences, Iranian Academy of Medical Sciences, Tehran, Iran. .
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Źródło:
Neurochemical research [Neurochem Res] 2023 Nov; Vol. 48 (11), pp. 3420-3429. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*/pharmacology
Circadian Rhythm*/physiology
Rats ; Animals ; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/pharmacology ; Suprachiasmatic Nucleus/physiology ; Receptors, Dopamine ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre.
Autorzy:
Ringuet MT; Department of Anatomy & Physiology, University of Melbourne, Melbourne, VIC, Australia.
Koo A; Department of Anatomy & Physiology, University of Melbourne, Melbourne, VIC, Australia.
Furness SGB; School of Biomedical Sciences, University of Queensland, Brisbane, QLD, Australia.; Monash Institute of Pharmaceutical Sciences, Melbourne, VIC, Australia.
McDougall SJ; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Furness JB; Department of Anatomy & Physiology, University of Melbourne, Melbourne, VIC, Australia.; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
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Źródło:
The Journal of physiology [J Physiol] 2023 Dec; Vol. 601 (23), pp. 5195-5211. Date of Electronic Publication: 2023 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*/pharmacology
Serotonin*/pharmacology
Humans ; Rats ; Animals ; Mice ; Receptors, Ghrelin ; Rats, Sprague-Dawley ; Rodentia ; Defecation/physiology ; Ghrelin/pharmacology ; Tyrosine 3-Monooxygenase/pharmacology ; Receptors, Serotonin ; Receptors, Dopamine D2
Czasopismo naukowe
Szczegóły
Tytuł:
The iron-dopamine D1 coupling modulates neural signatures of working memory across adult lifespan.
Autorzy:
Gustavsson J; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden. Electronic address: .
Johansson J; Faculty of Medicine, Department of Radiation Sciences, Umeå University, Sweden; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.
Falahati F; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden.
Andersson M; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden.
Papenberg G; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden.
Avelar-Pereira B; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden; Department of Psychiatry and Behavioural Sciences, School of Medicine, Stanford University, Stanford, California 94304, USA.
Bäckman L; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden.
Kalpouzos G; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden.
Salami A; Aging Research Center, Karolinska Institutet and Stockholm University, Sweden; Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden; Wallenberg Center for Molecular Medicine, Umeå University, Sweden.
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Źródło:
NeuroImage [Neuroimage] 2023 Oct 01; Vol. 279, pp. 120323. Date of Electronic Publication: 2023 Aug 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine*/physiology
Memory, Short-Term*/physiology
Female ; Adult ; Humans ; Young Adult ; Middle Aged ; Aged ; Longevity ; Iron ; Receptors, Dopamine D1/metabolism ; Prefrontal Cortex/physiology ; Memory Disorders
Czasopismo naukowe
Szczegóły
Tytuł:
Antioxidant system alterations and physiological characteristics of neonatal and juvenile DAT-KO rats.
Autorzy:
Apryatin SA; Institute of Experimental Medicine, St. Petersburg, Russia.; Institute of Translational Biomedicine, Saint Petersburg State University, St. Petersburg, Russia.
Traktirov DS; Institute of Experimental Medicine, St. Petersburg, Russia.
Karpenko MN; Institute of Experimental Medicine, St. Petersburg, Russia.; Peter the Great Saint Petersburg Polytechnic University, St. Petersburg, Russia.
Ivleva IS; Institute of Experimental Medicine, St. Petersburg, Russia.
Pestereva NS; Institute of Experimental Medicine, St. Petersburg, Russia.
Bolshakova MV; Peter the Great Saint Petersburg Polytechnic University, St. Petersburg, Russia.
Trofimov AN; Institute of Experimental Medicine, St. Petersburg, Russia.
Fesenko ZS; Institute of Translational Biomedicine, Saint Petersburg State University, St. Petersburg, Russia.
Klimenko VM; Institute of Experimental Medicine, St. Petersburg, Russia.
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Źródło:
Journal of neuroscience research [J Neurosci Res] 2023 Oct; Vol. 101 (10), pp. 1651-1661. Date of Electronic Publication: 2023 Jul 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine Plasma Membrane Transport Proteins*/genetics
Antioxidants*
Rats ; Male ; Female ; Animals ; Catalase/metabolism ; Dopamine/metabolism ; Glutathione/metabolism ; Glutathione Transferase/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Deep learning-based image analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra.
Autorzy:
Burkert N; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Roy S; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany. .
Häusler M; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Wuttke D; Wolution GmbH & Co. KG, 82152, Munich, Germany.
Müller S; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Wiemer J; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Hollmann H; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Oldrati M; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Ramirez-Franco J; UMR_S 1072, Aix Marseille Université, INSERM, Faculté de Médecine Secteur Nord, Marseille, France.; INT, Aix Marseille Université, CNRS, Campus Santé Timone, Marseille, France.
Benkert J; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Fauler M; Institute of General Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Duda J; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Goaillard JM; UMR_S 1072, Aix Marseille Université, INSERM, Faculté de Médecine Secteur Nord, Marseille, France.; INT, Aix Marseille Université, CNRS, Campus Santé Timone, Marseille, France.
Pötschke C; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.
Münchmeyer M; Wolution GmbH & Co. KG, 82152, Munich, Germany.; Department of Physics, University of Wisconsin-Madison, Madison, WI, USA.
Parlato R; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany.; Division of Neurodegenerative Disorders, Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neurosciences, Heidelberg University, 68167, Mannheim, Germany.
Liss B; Institute of Applied Physiology, Medical Faculty, Ulm University, 89081, Ulm, Germany. .; Linacre College & New College, Oxford University, OX1 2JD, Oxford, UK. .
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Źródło:
Communications biology [Commun Biol] 2023 Nov 10; Vol. 6 (1), pp. 1146. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Deep Learning*
Dopamine Plasma Membrane Transport Proteins*
Animals ; Humans ; Mice ; Dopamine ; Dopaminergic Neurons ; Substantia Nigra
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative study of the molecular mechanisms underlying the G protein and β-arrestin-dependent pathways that lead to ERKs activation upon stimulation by dopamine D 2 receptor.
Autorzy:
Liu H; School of Pharmaceutical Sciences, Guizhou University, Guiyang, China.
Acharya S; Mitchell Cancer Institute, School of Medicine, University of South Alabama, Mobile, AL, USA.
Sudan SK; Mitchell Cancer Institute, School of Medicine, University of South Alabama, Mobile, AL, USA.
Hu L; School of Pharmaceutical Sciences, Guizhou University, Guiyang, China.
Wu C; School of Pharmaceutical Sciences, Guizhou University, Guiyang, China.
Cao Y; Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, China.
Li H; Department of Pharmaceuticals, People's Hospital of Zunyi City Bo Zhou District, China.
Zhang X; School of Pharmaceutical Sciences, Guizhou University, Guiyang, China.
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Źródło:
The FEBS journal [FEBS J] 2023 Nov; Vol. 290 (21), pp. 5204-5233. Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine*/pharmacology
Extracellular Signal-Regulated MAP Kinases*
Arrestins/genetics ; beta-Arrestins ; GTP-Binding Proteins/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Receptors, Dopamine/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
D1R-5-HT2AR Uncoupling Reduces Depressive Behaviours via HDAC Signalling.
Autorzy:
Li W; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.; Department of Infectious Diseases and Shenzhen Key Laboratory for Endogenous Infections, the 6th Affiliated Hospital of Shenzhen University Health Science Center, No 89, Taoyuan Road, Nanshan District, Shenzhen, 518052, China.
Ali T; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Mou S; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.
Gong Q; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.
Li N; Department of Neurology, School of Medicine, Affiliated ZhongDa Hospital, Southeast University, Nanjing, China.; Precision Medicine Research Centre, Tomas Lindahl Nobel Laureate Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China.
Hao L; Hospital of Chengdu, University of Traditional Chinese Medicine, No.39 Shi-er-qiao Road, Chengdu, People's Republic of China.
Yu ZJ; Department of Infectious Diseases and Shenzhen Key Laboratory for Endogenous Infections, the 6th Affiliated Hospital of Shenzhen University Health Science Center, No 89, Taoyuan Road, Nanshan District, Shenzhen, 518052, China. .
Li S; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China. .; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, 518132, China. .; Campbell Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada. .; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. .
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Źródło:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2023 Oct; Vol. 20 (6), pp. 1875-1892. Date of Electronic Publication: 2023 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Dopamine*
Depressive Disorder, Major*
Mice ; Animals ; Serotonin ; Dopamine ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use
Czasopismo naukowe
Szczegóły
Tytuł:
The Effects of Chronic Marijuana Administration on 6-OHDA-Induced Learning & Memory Impairment and Hippocampal Dopamine and Cannabinoid Receptors Interaction in Male Rats.
Autorzy:
Haghparast E; Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran. elham_.; Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran. elham_.
Sheibani V; Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Komeili G; Department of Physiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Chahkandi M; Cellular and Molecular Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Disease, Zahedan University of Medical Sciences, Zahedan, Iran.
Rad NS; Infection Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Disease, Zahedan University of Medical Sciences, Zahedan, Iran.
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Źródło:
Neurochemical research [Neurochem Res] 2023 Jul; Vol. 48 (7), pp. 2220-2229. Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine*/metabolism
Cannabis*/metabolism
Rats ; Male ; Animals ; Oxidopamine/toxicity ; Receptors, Cannabinoid/metabolism ; Receptors, Dopamine D1/metabolism ; Receptors, Dopamine D2/metabolism ; Memory Disorders ; Spatial Learning ; Hippocampus/metabolism ; Cognition
Czasopismo naukowe
Szczegóły
Tytuł:
Assessing attention and impulsivity in the variable stimulus duration and variable intertrial interval rodent continuous performance test schedules using dopamine receptor antagonists in female C57BL/6JRj mice.
Autorzy:
Klem L; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
Nielsen MM; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
Gestsdóttir SB; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
Frandsen SL; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
Prichardt S; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.
Andreasen JT; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Aug; Vol. 240 (8), pp. 1651-1666. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Dopamine Antagonists*/pharmacology
Rodentia*
Mice ; Animals ; Female ; Mice, Inbred C57BL ; Receptors, Dopamine D1 ; Attention ; Impulsive Behavior ; Dopamine D2 Receptor Antagonists/pharmacology ; Benzazepines/pharmacology ; Dose-Response Relationship, Drug
Czasopismo naukowe
Szczegóły
Tytuł:
Neonatal olfactory bulbectomy induces anxiety-related behavior and modifies dopaminergic receptor expression in post-pubertal rats.
Autorzy:
Flores G; Lab. Neuropsiquiatría, Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Gómez-Villalobos MJ; Lab. Fisiología Cardiovascular, Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Iannitti T; Department of Medical Sciences, Section of Experimental Medicine, University of Ferrara, Ferrara, Italy.
Morales-Medina JC; Centro de Investigación en Reproducción Animal, CINVESTAV-Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico.
Pokaż więcej
Źródło:
Synapse (New York, N.Y.) [Synapse] 2023 Jul; Vol. 77 (4), pp. e22272. Date of Electronic Publication: 2023 May 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine*/metabolism
Anti-Anxiety Agents*/pharmacology
Rats ; Animals ; Smell ; Receptors, Dopamine/metabolism ; Nucleus Accumbens ; Anxiety ; Receptors, Dopamine D1/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Effects of dopamine D2 receptor antagonists on retinal pigment epithelial/choroid complex metabolism in form-deprived myopic guinea pigs.
Autorzy:
Wei P; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, PR China.; Nankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, PR China.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, PR China.
Han G; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, PR China.; Nankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, PR China.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, PR China.
Wang Y; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, PR China.; Nankai University Eye Institute, Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, PR China.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, PR China.
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Źródło:
Proteomics [Proteomics] 2023 Sep; Vol. 23 (18), pp. e2200325. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine*/metabolism
Myopia*/drug therapy
Myopia*/etiology
Myopia*/metabolism
Guinea Pigs ; Animals ; Dopamine D2 Receptor Antagonists/pharmacology ; Dopamine D2 Receptor Antagonists/metabolism ; Retina/metabolism ; Choroid/metabolism ; Choroid/pathology ; Glutamates/metabolism ; Disease Models, Animal
Czasopismo naukowe
Szczegóły
Tytuł:
The Addiction-Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D 2 Receptor-Expressing Neurons.
Autorzy:
Montalban E; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France. Electronic address: .
Walle R; Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, Bordeaux, France.
Castel J; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Ansoult A; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Hassouna R; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Foppen E; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Fang X; Modern Diet and Physiology Research Center, New Haven, Connecticut; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Hutelin Z; Modern Diet and Physiology Research Center, New Haven, Connecticut; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Mickus S; Modern Diet and Physiology Research Center, New Haven, Connecticut; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Perszyk E; Modern Diet and Physiology Research Center, New Haven, Connecticut; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Petitbon A; Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, Bordeaux, France.
Berthelet J; Université Paris Cité, CNRS, Unité Epigenetique et Destin Cellulaire, Paris, France.
Rodrigues-Lima F; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Cebrian-Serrano A; Institute for Diabetes and Obesity, Helmholtz Diabetes Center (HDC), Helmholtz Zentrum München, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany.
Gangarossa G; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Martin C; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France.
Trifilieff P; Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, Bordeaux, France.
Bosch-Bouju C; Université Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, Bordeaux, France.
Small DM; Modern Diet and Physiology Research Center, New Haven, Connecticut; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Luquet S; Université Paris Cité, CNRS, Unité de Biologie Fonctionnelle et Adaptative, Paris, France; Modern Diet and Physiology Research Center, New Haven, Connecticut. Electronic address: .
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Źródło:
Biological psychiatry [Biol Psychiatry] 2023 Sep 01; Vol. 94 (5), pp. 424-436. Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine*
Behavior, Addictive*
Humans ; Receptors, Dopamine D2/genetics ; Receptors, Dopamine D2/metabolism ; Neurons/metabolism ; Reward
Czasopismo naukowe
Szczegóły
Tytuł:
Cortical dopamine D5 receptors regulate neuronal circuit oscillatory activity and memory in rats.
Autorzy:
Albeely AM; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Nolan CJ; Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.
Rasmussen DJ; Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.
Bailey CDC; Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.
Perreault ML; Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Sep; Vol. 29 (9), pp. 2469-2480. Date of Electronic Publication: 2023 Apr 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Dopamine D5*/genetics
Receptors, Dopamine D5*/metabolism
Neurons*/metabolism
Rats ; Male ; Animals ; Glycogen Synthase Kinase 3 beta ; Hippocampus/metabolism ; Prefrontal Cortex/metabolism ; Receptors, Dopamine D1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploring Structural Determinants of Bias among D4 Subtype-Selective Dopamine Receptor Agonists.
Autorzy:
Graßl F; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Bock L; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Huete-Huerta González Á; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Schiller M; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Gmeiner P; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
König J; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Fromm MF; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Hübner H; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Heinrich MR; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany.
Pokaż więcej
Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Jul 27; Vol. 66 (14), pp. 9710-9730. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine Agonists*/pharmacology
Dopamine Agonists*/chemistry
Receptors, Dopamine D4*/chemistry
Quinpirole ; Dopamine ; Ligands
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 206202

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