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Tytuł:
Modulated Electro-Hyperthermia Accelerates Tumor Delivery and Improves Anticancer Activity of Doxorubicin Encapsulated in Lyso-Thermosensitive Liposomes in 4T1-Tumor-Bearing Mice.
Autorzy:
Aloss K; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Bokhari SMZ; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Leroy Viana PH; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Giunashvili N; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Schvarcz CA; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.; HUN-REN-SU Cerebrovascular and Neurocognitive Diseases Research Group, 1094 Budapest, Hungary.
Szénási G; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Bócsi D; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Koós Z; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Storm G; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3508 Utrecht, The Netherlands.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Miklós Z; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.; National Korányi Institute for Pulmonology, 1122 Budapest, Hungary.
Benyó Z; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.; HUN-REN-SU Cerebrovascular and Neurocognitive Diseases Research Group, 1094 Budapest, Hungary.
Hamar P; Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 07; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperthermia, Induced*/methods
Neoplasms*
Doxorubicin/*analogs & derivatives
Mice ; Animals ; Liposomes ; Ki-67 Antigen ; Doxorubicin/pharmacology ; Hyperthermia ; Cell Line, Tumor ; Polyethylene Glycols
Czasopismo naukowe
Tytuł:
Combination Treatment with EGFR Inhibitor and Doxorubicin Synergistically Inhibits Proliferation of MCF-7 Cells and MDA-MB-231 Triple-Negative Breast Cancer Cells In Vitro.
Autorzy:
Abrahams B; Department of Basic Medical Sciences, Faculty of Health Sciences, University of the Free State, Bloemfontein 9301, South Africa.
Gerber A; Department of Basic Medical Sciences, Faculty of Health Sciences, University of the Free State, Bloemfontein 9301, South Africa.
Hiss DC; Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Bellville 7535, South Africa.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/pharmacology
ErbB Receptors*/antagonists & inhibitors
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/metabolism
Female ; Humans ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; MCF-7 Cells ; Drug Synergism
Czasopismo naukowe
Tytuł:
Development of PET Radioisotope Copper-64-Labeled Theranostic Immunoliposomes for EGFR Overexpressing Cancer-Targeted Therapy and Imaging.
Autorzy:
Jeong HY; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Kang SJ; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Kim MW; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Jeong IH; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Choi MJ; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Jung C; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Song IH; Division of RI-Convergence Research, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Lee TS; Division of RI-Convergence Research, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Park YS; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 02; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Copper Radioisotopes*
Doxorubicin*/therapeutic use
Doxorubicin*/analogs & derivatives
Liposomes*
Neoplasms*/diagnostic imaging
Neoplasms*/drug therapy
Animals ; Humans ; Mice ; Cell Line, Tumor ; Copper ; Drug Delivery Systems/methods ; ErbB Receptors/metabolism ; Polyethylene Glycols ; Positron-Emission Tomography ; Precision Medicine
Czasopismo naukowe
Tytuł:
A real-world analysis of FDA Adverse Event Reporting System (FAERS) events for liposomal and conventional doxorubicins.
Autorzy:
Su H; Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jia J; Department of Pharmacy, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Mao Y; Medical School, Kunming University of Science and Technology, Kunming, Yunnan, China.
Zhu R; Department of Pharmacy, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Li Z; Department of Dermatology, Qilu Hospital, Shandong University, Jinan, Shandong, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 01; Vol. 14 (1), pp. 5095. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/drug therapy
Neutropenia*/chemically induced
Pneumonia*/drug therapy
Doxorubicin/*analogs & derivatives
Humans ; Cardiotoxicity/drug therapy ; Bayes Theorem ; Doxorubicin/adverse effects ; Liposomes ; Polyethylene Glycols
Czasopismo naukowe
Tytuł:
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Autorzy:
Lan Y; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, P.R. China.
Tian F; Department of Endocrine, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, P.R. China.
Tang H; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, P.R. China.
Pu P; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, P.R. China.
He Q; Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, P.R. China.
Duan L; Department of General Practice, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2024 May; Vol. 29 (5). Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Aminopyridines*
Apigenin*/pharmacology
Apigenin*/therapeutic use
Cardiotoxicity*
Doxorubicin*/analogs & derivatives
Doxorubicin*/toxicity
Ferroptosis*/drug effects
Sulfonamides*
Animals ; Rats ; Apoptosis/drug effects ; NADPH Oxidase 2/drug effects ; NADPH Oxidase 2/genetics ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł:
Effects of Doxorubicin on Extracellular Matrix Regulation in Primary Cardiac Fibroblasts from Mice.
Autorzy:
Skaggs C; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.
Nick S; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.
Patricelli C; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.; Biomolecular Sciences Graduate Program, Boise State University, Boise, ID, 83725, USA.
Bond L; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.
Woods K; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.
Woodbury L; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.; Biomolecular Sciences Graduate Program, Boise State University, Boise, ID, 83725, USA.
Oxford JT; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA.; Biomolecular Sciences Graduate Program, Boise State University, Boise, ID, 83725, USA.; Department of Biological Sciences, Boise State University, Boise, ID, 83725, USA.
Pu X; Biomolecular Research Center, Boise State University, Boise, ID, 83725, USA. .; Biomolecular Sciences Graduate Program, Boise State University, Boise, ID, 83725, USA. .; Department of Biological Sciences, Boise State University, Boise, ID, 83725, USA. .
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Źródło:
BMC research notes [BMC Res Notes] 2023 Nov 16; Vol. 16 (1), pp. 340. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiotoxicity*/metabolism
Doxorubicin*/pharmacology
Humans ; Child ; Mice ; Animals ; Myocytes, Cardiac ; Collagen/metabolism ; Collagen/pharmacology ; Extracellular Matrix/metabolism ; Fibroblasts ; Apoptosis ; Oxidative Stress
Czasopismo naukowe
Tytuł:
Enhanced Sensitivity of A549 Cells to Doxorubicin with WS 2 and WSe 2 Nanosheets via the Induction of Autophagy.
Autorzy:
Jin W; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.
Yang T; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.
Jia J; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.
Jia J; Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, Guangzhou University, Guangzhou 510006, China.
Zhou X; College of Science & Technology, Hebei Agricultural University, Huanghua 061100, China.; Hebei Key Laboratory of Analysis and Control of Zoonotic Pathogenic Microorganism, Baoding 071000, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 18; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/pharmacology
Lung Neoplasms*
Humans ; Animals ; Mice ; A549 Cells ; Autophagy ; Epithelial Cells
Czasopismo naukowe
Tytuł:
B7H3 targeting gold nanocage pH-sensitive conjugates for precise and synergistic chemo-photothermal therapy against NSCLC.
Autorzy:
Chen B; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Zheng K; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Fang S; The Cancer Center, Union Hospital, Fujian Medical University, Fuzhou, 350122, China.
Huang K; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Chu C; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Zhuang J; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Lin J; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Li S; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Yao H; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Liu A; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Liu G; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China. .
Lin J; The Cancer Center, Union Hospital, Fujian Medical University, Fuzhou, 350122, China. .; The Department of Otolaryngology, Head and Neck Surgery, University of Minnesota Medical School, Minneapolis, 55404, USA. .
Lin X; Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China. .; Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Oct 17; Vol. 21 (1), pp. 378. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Doxorubicin*/pharmacology
Doxorubicin*/therapeutic use
Lung Neoplasms*/drug therapy
Nanoparticles*
Photothermal Therapy*/methods
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; B7 Antigens ; Cell Line, Tumor ; Drug Liberation ; Gold ; Hydrogen-Ion Concentration ; Hyperthermia, Induced ; Phototherapy ; Tumor Microenvironment ; Animals ; Mice ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Differences in Physico-Chemical Properties and Immunological Response in Nanosimilar Complex Drugs: The Case of Liposomal Doxorubicin.
Autorzy:
Lipsa D; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Magrì D; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Della Camera G; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.; Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), 80131 Naples, Italy.
La Spina R; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Cella C; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Garmendia-Aguirre I; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Mehn D; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Ruiz-Moreno A; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Fumagalli F; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Calzolai L; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Gioria S; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 02; Vol. 24 (17). Date of Electronic Publication: 2023 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/pharmacology
Polyethylene Glycols*
Excipients ; Liposomes
Czasopismo naukowe
Tytuł:
Wnt10b protects cardiomyocytes against doxorubicin-induced cell death via MAPK modulation.
Autorzy:
Chen L; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, United States of America.
Byer SH; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, United States of America.
Holder R; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, United States of America.
Wu L; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, United States of America.
Burkey K; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, United States of America.
Shah Z; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Oct 19; Vol. 18 (10), pp. e0277747. Date of Electronic Publication: 2023 Oct 19 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/toxicity
Myocytes, Cardiac*/metabolism
Animals ; Humans ; Mice ; Antibiotics, Antineoplastic/toxicity ; Apoptosis ; Cardiotoxicity/metabolism ; Oxidative Stress ; Wnt Proteins/metabolism
Czasopismo naukowe
Tytuł:
Low-frequency magnetic fields potentiate plasma-modified magneto-electric nanoparticle drug loading for anticancer activity in vitro and in vivo.
Autorzy:
Mahdikia H; Laser and Plasma Research Institute, Shahid Beheshti University, Tehran, Iran.; Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany.
Saadati F; Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany.
Alizadeh AM; Breast Diseases Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran. .
Khalighfard S; Research Center on Developing Advanced Technologies, Tehran, Iran.
Bekeschus S; Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany.
Shokri B; Laser and Plasma Research Institute, Shahid Beheshti University, Tehran, Iran.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 16; Vol. 13 (1), pp. 17536. Date of Electronic Publication: 2023 Oct 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Doxorubicin*/pharmacology
Nanoparticles*/chemistry
Animals ; Mice ; Magnetic Fields ; Chemical Phenomena ; Magnetics
Czasopismo naukowe
Tytuł:
Artemether ameliorates adriamycin induced cardiac atrophy in mice.
Autorzy:
Weng W; Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Futian, Shenzhen, Guangdong 518033, P.R. China.
Yu X; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Futian, Shenzhen, Guangdong 518033, P.R. China.
Dong Y; Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Futian, Shenzhen, Guangdong 518033, P.R. China.
Wang T; Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518033, P.R. China.
Shao M; Department of Pathology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Futian, Shenzhen, Guangdong 518033, P.R. China.
Sun H; Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Futian, Shenzhen, Guangdong 518033, P.R. China.
Han P; Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518033, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2023 Aug; Vol. 28 (2). Date of Electronic Publication: 2023 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/adverse effects
Cardiotoxicity*
Animals ; Mice ; Hydrogen Peroxide ; Myocytes, Cardiac ; Artemether/pharmacology ; Atrophy
Czasopismo naukowe
Tytuł:
Suppression of VEGF and inflammatory cytokines, modulation of Annexin A1 and organ functions by galloylquinic acids in breast cancer model.
Autorzy:
Abd El-Salam M; Department of Pharmacognosy, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 11152, Egypt. .; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, D02 VN51, Ireland. .
El-Tanbouly G; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 11152, Egypt.
Bastos J; Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, 14040-900, Brazil.
Metwaly H; Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 28; Vol. 13 (1), pp. 12268. Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Annexin A1*
Antineoplastic Agents*/pharmacology
Carcinoma, Ehrlich Tumor*/drug therapy
Carcinoma, Ehrlich Tumor*/pathology
Doxorubicin*/pharmacology
Doxorubicin*/therapeutic use
Animals ; Mice ; Ascites ; Cytokines/therapeutic use ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł:
COX5A Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress, Mitochondrial Dysfunction and Cardiomyocyte Apoptosis.
Autorzy:
Zhang P; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Lu H; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Wu Y; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Lu D; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Li C; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Yang X; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Chen Z; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Qian J; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
Ge J; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 20; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiomyopathies*/metabolism
Cardiotoxicity*/metabolism
Doxorubicin*/adverse effects
Electron Transport Complex IV*/genetics
Electron Transport Complex IV*/metabolism
Animals ; Humans ; Mice ; Apoptosis ; Mice, Inbred C57BL ; Mitochondria/metabolism ; Myocytes, Cardiac/metabolism ; Oxidative Stress ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Effects of Exercise Preconditioning on Doxorubicin-Induced Liver and Kidney Toxicity in Male and Female Rats.
Autorzy:
Boeno FP; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL 32608, USA.
Patel J; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL 32608, USA.
Montalvo RN; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL 32608, USA.
Lapierre-Nguyen SS; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL 32608, USA.
Schreiber CM; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL 32608, USA.
Smuder AJ; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL 32608, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 16; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/toxicity
Doxorubicin*/metabolism
Liver*/metabolism
Rats ; Male ; Female ; Animals ; Rats, Sprague-Dawley ; Creatinine/metabolism ; Kidney/metabolism ; Oxidative Stress ; Antibiotics, Antineoplastic/pharmacology
Czasopismo naukowe
Tytuł:
Impact of doxorubicin-loaded ferritin nanocages (FerOX) vs. free doxorubicin on T lymphocytes: a translational clinical study on breast cancer patients undergoing neoadjuvant chemotherapy.
Autorzy:
Sevieri M; Department of Biomedical and Clinical Sciences, Università di Milano, 20157, Milan, Italy.
Andreata F; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Mainini F; Department of Biomedical and Clinical Sciences, Università di Milano, 20157, Milan, Italy.
Signati L; Department of Biomedical and Clinical Sciences, Università di Milano, 20157, Milan, Italy.; Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Piccotti F; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Truffi M; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Bonizzi A; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Sitia L; Department of Biomedical and Clinical Sciences, Università di Milano, 20157, Milan, Italy.
Pigliacelli C; Laboratory of Supramolecular and Bio-Nanomaterials (SBNLab), Department of Chemistry, Materials, and Chemical Engineering 'Giulio Natta', Politecnico di Milano, 20131, Milan, Italy.
Morasso C; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Tagliaferri B; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Corsi F; Department of Biomedical and Clinical Sciences, Università di Milano, 20157, Milan, Italy. .; Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy. .
Mazzucchelli S; Department of Biomedical and Clinical Sciences, Università di Milano, 20157, Milan, Italy. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Apr 15; Vol. 22 (1), pp. 184. Date of Electronic Publication: 2024 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Humans ; Female ; Leukocytes, Mononuclear ; Neoadjuvant Therapy ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Targeting of focal adhesion kinase enhances the immunogenic cell death of PEGylated liposome doxorubicin to optimize therapeutic responses of immune checkpoint blockade.
Autorzy:
Zhang B; State Key Laboratory for Medical Genomics, Collaborative Innovation Center of Hematology, Shanghai Institute of HematologyNational Research Center for Translational MedicineRuijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li N; Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinses Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Gao J; State Key Laboratory for Medical Genomics, Collaborative Innovation Center of Hematology, Shanghai Institute of HematologyNational Research Center for Translational MedicineRuijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhao Y; Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinses Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jiang J; InxMed (Shanghai) Co., Ltd, Beijing, China.
Xie S; InxMed (Shanghai) Co., Ltd, Beijing, China.
Zhang C; Department of Pathology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Zhang Q; Laboratory of Obstetrics and Gynecology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Liu L; InxMed (Shanghai) Co., Ltd, Beijing, China.
Wang Z; InxMed (Shanghai) Co., Ltd, Beijing, China.
Ji D; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. .
Wu L; Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinses Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
Ren R; State Key Laboratory for Medical Genomics, Collaborative Innovation Center of Hematology, Shanghai Institute of HematologyNational Research Center for Translational MedicineRuijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; International Center for Aging and Cancer, Hainan Medical University, Hainan Province, Haikou, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 19; Vol. 43 (1), pp. 51. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Liposomes*
Neoplasms*/drug therapy
Neoplasms*/pathology
Animals ; Humans ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Focal Adhesion Protein-Tyrosine Kinases/antagonists & inhibitors ; Focal Adhesion Protein-Tyrosine Kinases/drug effects ; Immune Checkpoint Inhibitors/therapeutic use ; Immunogenic Cell Death ; Polyethylene Glycols ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Synergistic Effects of Temozolomide and Doxorubicin in the Treatment of Glioblastoma Multiforme: Enhancing Efficacy through Combination Therapy.
Autorzy:
Dhungel L; Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Rowsey ME; Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Harris C; Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Raucher D; Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 14; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/pathology
Brain Neoplasms*/pathology
Humans ; Temozolomide/pharmacology ; Antineoplastic Agents, Alkylating/pharmacology ; Drug Resistance, Neoplasm ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
The Temozolomide-Doxorubicin paradox in Glioblastoma in vitro-in silico preclinical drug-screening.
Autorzy:
Oraiopoulou ME; Institute of Computer Science (ICS), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece.; Cancer Research UK - Cambridge Institute, University of Cambridge, Cambridge, UK.
Tzamali E; Institute of Computer Science (ICS), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece.
Psycharakis SE; Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), Heraklion, Greece.; School of Medicine, University of Crete, Heraklion, Greece.
Tzedakis G; Institute of Computer Science (ICS), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece.
Makatounakis T; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology Hellas (FORTH), Heraklion, Greece.
Manolitsi K; University General Hospital of Heraklion (PAGNI), Heraklion, Greece.
Drakos E; School of Medicine, University of Crete, Heraklion, Greece.; University General Hospital of Heraklion (PAGNI), Heraklion, Greece.
Vakis AF; School of Medicine, University of Crete, Heraklion, Greece.; University General Hospital of Heraklion (PAGNI), Heraklion, Greece.
Zacharakis G; Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), Heraklion, Greece.
Papamatheakis J; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology Hellas (FORTH), Heraklion, Greece.; Department of Biology, University of Crete, Heraklion, Greece.
Sakkalis V; Institute of Computer Science (ICS), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 14; Vol. 14 (1), pp. 3759. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/drug therapy
Glioblastoma*/metabolism
Brain Neoplasms*/drug therapy
Brain Neoplasms*/metabolism
Humans ; Temozolomide/pharmacology ; Temozolomide/therapeutic use ; Cell Line, Tumor ; Neoplasm Recurrence, Local ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use
Czasopismo naukowe
Tytuł:
From Design to Study of Liposome-Driven Drug Release Part 1: Impact of Temperature and pH on Environment.
Autorzy:
Kozik V; Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
Pentak D; Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.; Faculty of Chemistry, University of Opole, Oleska 48, 45-052 Opole, Poland.
Paździor M; Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
Zięba A; Department of Organic Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellońska 4, 41-200 Sosnowiec, Poland.
Bąk A; Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 20; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Liposomes*/chemistry
Doxorubicin*/chemistry
Temperature ; Drug Liberation ; Hydrogen-Ion Concentration ; Drug Delivery Systems
Czasopismo naukowe

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