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    Wyświetlanie 1-16 z 16
    Tytuł:
    The impact of short-course hypofractionated radiotherapy on multimodality treatment utilisation, compliance, and outcome in glioblastoma patients: a Danish patterns of care study.
    Autorzy:
    Vamsi VS; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
    Lukacova S; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
    Dahlrot RH; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Guldberg TL; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.
    Korshøj AR; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark.
    Muhic A; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Department of Oncology, Copenhagen University Hospital, Copenhagen, Denmark.
    Trip AK; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
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    Źródło:
    Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2023 Nov; Vol. 62 (11), pp. 1511-1519. Date of Electronic Publication: 2023 Aug 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Glioblastoma*/therapy
    Adult ; Humans ; Retrospective Studies ; Radiation Dose Hypofractionation ; Dose Fractionation, Radiation ; Denmark ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A national study on the inter-observer variability in the delineation of organs at risk in the brain.
    Autorzy:
    Lorenzen EL; Laboratory of Radiation Physics, Odense University Hospital, Odense, Denmark.
    Kallehauge JF; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
    Byskov CS; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
    Dahlrot RH; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Haslund CA; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.
    Guldberg TL; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.
    Lassen-Ramshad Y; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
    Lukacova S; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
    Muhic A; Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
    Witt Nyström P; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
    Haldbo-Classen L; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
    Bahij I; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
    Larsen L; Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.
    Weber B; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
    Hansen CR; Laboratory of Radiation Physics, Odense University Hospital, Odense, Denmark.; Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2021 Nov; Vol. 60 (11), pp. 1548-1554. Date of Electronic Publication: 2021 Oct 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Organs at Risk*
    Radiotherapy Planning, Computer-Assisted*
    Brain/diagnostic imaging ; Humans ; Observer Variation ; Pilot Projects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Study protocol for OptimalTTF-2: enhancing Tumor Treating Fields with skull remodeling surgery for first recurrence glioblastoma: a phase 2, multi-center, randomized, prospective, interventional trial.
    Autorzy:
    Mikic N; Department of Neurosurgery, Aarhus University Hospital, Palle Juul-Jensens Blvd 165, 8200, Aarhus, Denmark. .; Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Blvd. 82, 8200, Aarhus, Denmark. .
    Poulsen FR; Department of Neurosurgery, Odense University Hospital, Kløvervænget 47, 5000, Odense, Denmark.; Clinical Institute BRIDGE (Brain Research InterDisciplinary Guided Excellence), University of Southern Denmark, Winsløwparken 19, 5000, Odense, Denmark.
    Kristoffersen KB; Department of Oncology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200, Aarhus, Denmark.
    Laursen RJ; Department of Neurosurgery, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
    Guldberg TL; Department of Oncology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
    Skjøth-Rasmussen J; Department of Neurosurgery, Rigshospitalet, Inge Lehmanns Vej 6, 2100, København Ø, Denmark.
    Wong ET; Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.; Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA.
    Møller S; Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100, København Ø, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Kløvervænget 19, 5000, Odense, Denmark.
    Sørensen JCH; Department of Neurosurgery, Aarhus University Hospital, Palle Juul-Jensens Blvd 165, 8200, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Blvd. 82, 8200, Aarhus, Denmark.
    Korshøj AR; Department of Neurosurgery, Aarhus University Hospital, Palle Juul-Jensens Blvd 165, 8200, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Blvd. 82, 8200, Aarhus, Denmark.
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    Źródło:
    BMC cancer [BMC Cancer] 2021 Sep 09; Vol. 21 (1), pp. 1010. Date of Electronic Publication: 2021 Sep 09.
    Typ publikacji:
    Clinical Trial Protocol; Journal Article
    MeSH Terms:
    Brain Neoplasms*/surgery
    Glioblastoma*/mortality
    Glioblastoma*/surgery
    Neoplasm Recurrence, Local*/mortality
    Neoplasm Recurrence, Local*/surgery
    Osteotomy*/methods
    Skull*/surgery
    Adult ; Humans ; Follow-Up Studies ; Karnofsky Performance Status ; Progression-Free Survival ; Prospective Studies ; Quality of Life ; Time Factors ; Transducers ; Multicenter Studies as Topic ; Clinical Trials, Phase II as Topic ; Randomized Controlled Trials as Topic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Prognostic role of Ki-67 in glioblastomas excluding contribution from non-neoplastic cells.
    Autorzy:
    Dahlrot RH; Department of Pathology, Odense University Hospital, Odense, Denmark. rikke.dahlrot@rsyd.dk.; Department of Oncology, Odense University Hospital, Odense, Denmark. rikke.dahlrot@rsyd.dk.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. rikke.dahlrot@rsyd.dk.
    Bangsø JA; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Petersen JK; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Rosager AM; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Reifenberger G; Department of Pathology, Odense University Hospital, Odense, Denmark.; Institute of Neuropathology, Heinrich Heine University, Düsseldorf, Germany.
    Hansen S; Department of Oncology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine and Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.
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    Źródło:
    Scientific reports [Sci Rep] 2021 Sep 09; Vol. 11 (1), pp. 17918. Date of Electronic Publication: 2021 Sep 09.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Ki-67 Antigen/*metabolism
    Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Cohort Studies ; Female ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Prognosis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Targeted next-generation sequencing of adult gliomas for retrospective prognostic evaluation and up-front diagnostics.
    Autorzy:
    Petersen JK; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Boldt HB; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Blach S; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Dahlrot RH; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Hansen S; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Burton M; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
    Thomassen M; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
    Kruse T; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
    Poulsen FR; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.
    Andreasen L; Department of Pathology, Vejle Hospital, Vejle, Denmark.
    Hager H; Department of Pathology, Vejle Hospital, Vejle, Denmark.
    Ulhøi BP; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
    Lukacova S; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
    Reifenberger G; Institute of Neuropathology, Heinrich Heine University, Düsseldorf, Germany.; German Cancer Consortium (DKTK), Partner site Essen/Düsseldorf, Düsseldorf, Germany.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2021 Feb; Vol. 47 (1), pp. 108-126. Date of Electronic Publication: 2020 Aug 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    High-Throughput Nucleotide Sequencing*
    Biomarkers, Tumor/*genetics
    Brain Neoplasms/*diagnosis
    Glioma/*pathology
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Astrocytoma/diagnosis ; Astrocytoma/genetics ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Female ; Glioblastoma/diagnosis ; Glioblastoma/genetics ; Glioma/diagnosis ; Glioma/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Male ; Middle Aged ; Mutation/genetics ; Prognosis ; Telomerase/genetics ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Quality of life in patients with cancer during the COVID-19 pandemic - a Danish cross-sectional study (COPICADS).
    Autorzy:
    Jeppesen SS; Department of Oncology, Odense University Hospital, Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense C, Denmark.; On behalf of the Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Odense C, Denmark.; OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense C, Denmark.
    Bentsen KK; Department of Oncology, Odense University Hospital, Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense C, Denmark.; On behalf of the Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Odense C, Denmark.
    Jørgensen TL; Department of Oncology, Odense University Hospital, Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense C, Denmark.; On behalf of the Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Odense C, Denmark.
    Holm HS; Department of Oncology, Odense University Hospital, Odense C, Denmark.
    Holst-Christensen L; Department of Oncology, Odense University Hospital, Odense C, Denmark.
    Tarpgaard LS; Department of Oncology, Odense University Hospital, Odense C, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense C, Denmark.
    Eckhoff L; Department of Oncology, Odense University Hospital, Odense C, Denmark.; OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense C, Denmark.
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    Źródło:
    Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2021 Jan; Vol. 60 (1), pp. 4-12. Date of Electronic Publication: 2020 Oct 08.
    Typ publikacji:
    Journal Article; Observational Study
    MeSH Terms:
    COVID-19*
    Cognition*
    Psychosocial Functioning*
    Quality of Life*
    Neoplasms/*physiopathology
    Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Comorbidity ; Cross-Sectional Studies ; Denmark ; Employment ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/psychology ; Residence Characteristics ; Role ; SARS-CoV-2 ; Sex Factors ; Social Interaction ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Expression and prognostic value of the transcription factors EGR1 and EGR3 in gliomas.
    Autorzy:
    Knudsen AM; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. .; Department of Pathology, Odense University Hospital, Odense, Denmark. .
    Eilertsen I; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Kielland S; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Pedersen MW; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Sørensen MD; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Dahlrot RH; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Boldt HB; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Munthe S; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.
    Poulsen FR; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.
    Kristensen BW; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
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    Źródło:
    Scientific reports [Sci Rep] 2020 Jun 09; Vol. 10 (1), pp. 9285. Date of Electronic Publication: 2020 Jun 09.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Biomarkers, Tumor/*genetics
    Early Growth Response Protein 1/*genetics
    Early Growth Response Protein 3/*genetics
    Glioblastoma/*genetics
    Glioblastoma/*pathology
    Cell Movement/genetics ; DNA Methylation/genetics ; DNA Modification Methylases/genetics ; DNA Modification Methylases/metabolism ; DNA Repair Enzymes/genetics ; DNA Repair Enzymes/metabolism ; Disease Progression ; Early Growth Response Protein 1/metabolism ; Early Growth Response Protein 3/metabolism ; Female ; Glioblastoma/diagnosis ; Humans ; Male ; Prognosis ; Promoter Regions, Genetic/genetics ; Tumor Suppressor Protein p53/metabolism ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival.
    Autorzy:
    Beier CP; Department of Neurology, Odense University Hospital, Odense, Denmark. .; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. .
    Rasmussen T; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Tenstad HB; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Aarø JS; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Sørensen MF; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Heimisdóttir SB; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Svenningsen P; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
    Riemenschneider MJ; Department for Neuropathology, Regensburg University Hospital, Odense, Germany.
    Beier D; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    Scientific reports [Sci Rep] 2018 Oct 08; Vol. 8 (1), pp. 14965. Date of Electronic Publication: 2018 Oct 08.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Neurogenesis*
    Brain Neoplasms/*complications
    Glioma/*complications
    Neurons/*pathology
    Seizures/*etiology
    Adult ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cohort Studies ; Glioma/genetics ; Glioma/pathology ; Humans ; Isocitrate Dehydrogenase/genetics ; Mutation ; Neurons/metabolism ; Retrospective Studies ; Seizures/genetics ; Seizures/pathology ; Survival Analysis ; Synapses/metabolism ; Synapses/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Evaluation of the proliferation marker Ki-67 in gliomas: Interobserver variability and digital quantification.
    Autorzy:
    Nielsen LAG; Department of Pathology, Odense University Hospital, J. B. Winsløws Vej 15, Entrance 240, DK-5000, Odense C, Denmark. .; Department of Pathology, Hospital of Southern Jutland/ Sygehus Sønderjylland, Kresten Philipsens Vej 15, Dk-6200, Aabenraa, Denmark. .
    Bangsø JA; Department of Pathology, Odense University Hospital, J. B. Winsløws Vej 15, Entrance 240, DK-5000, Odense C, Denmark.
    Lindahl KH; Department of Pathology, Odense University Hospital, J. B. Winsløws Vej 15, Entrance 240, DK-5000, Odense C, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Sdr. Boulevard 29, Dk-5000, Odense C, Denmark.
    Hjelmborg JVB; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, J.B. Winsløws Vej 9, Entrance B, 1st, Dk-5000, Odense C, Denmark.
    Hansen S; Department of Oncology, Odense University Hospital, Sdr. Boulevard 29, Dk-5000, Odense C, Denmark.; Department of Clinical Research, University of Southern Denmark, J. B. Winsløws Vej 15, Entrance 240, DK-5000, Odense C, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, J. B. Winsløws Vej 15, Entrance 240, DK-5000, Odense C, Denmark. .; Department of Clinical Research, University of Southern Denmark, J. B. Winsløws Vej 15, Entrance 240, DK-5000, Odense C, Denmark. .
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    Źródło:
    Diagnostic pathology [Diagn Pathol] 2018 Jun 09; Vol. 13 (1), pp. 38. Date of Electronic Publication: 2018 Jun 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Brain Neoplasms/*pathology
    Glioma/*pathology
    Ki-67 Antigen/*analysis
    Mitotic Index/*standards
    Neoplasm Grading/*methods
    Biomarkers, Tumor/analysis ; Biomarkers, Tumor/standards ; Cell Proliferation ; Humans ; Image Processing, Computer-Assisted ; Neoplasm Grading/standards ; Observer Variation ; Pathology, Clinical/methods ; Pathology, Clinical/standards
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Tumour-associated microglia/macrophages predict poor prognosis in high-grade gliomas and correlate with an aggressive tumour subtype.
    Autorzy:
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Boldt HB; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Hansen S; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2018 Feb; Vol. 44 (2), pp. 185-206. Date of Electronic Publication: 2017 Sep 05.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Brain Neoplasms/*pathology
    Glioma/*pathology
    Macrophages/*pathology
    Microglia/*pathology
    Brain Neoplasms/metabolism ; Brain Neoplasms/mortality ; DNA Methylation ; Female ; Glioma/metabolism ; Glioma/mortality ; Humans ; Macrophages/metabolism ; Male ; Microglia/metabolism ; O(6)-Methylguanine-DNA Methyltransferase/metabolism ; Prognosis ; Survival Rate ; Tumor Microenvironment/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Prognostic value of O-6-methylguanine-DNA methyltransferase (MGMT) protein expression in glioblastoma excluding nontumour cells from the analysis.
    Autorzy:
    Dahlrot RH; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Dowsett J; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Fosmark S; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Malmström A; Department of Advanced Home Care, Linköping University, Linköping, Sweden.; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
    Henriksson R; Department of Radiation Sciences & Oncology, Umeå University, Umeå, Sweden.; Regional Cancer Center Stockholm Gotland, Stockholm, Sweden.
    Boldt H; Department of Pathology, Odense University Hospital, Odense, Denmark.
    de Stricker K; Department of Pathology, Odense University Hospital, Odense, Denmark.
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Poulsen HS; Department of Radiation Biology & Oncology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark.
    Lysiak M; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
    Söderkvist P; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
    Rosell J; Regional Cancer Center South East Sweden and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
    Hansen S; Department of Oncology, Odense University Hospital, Odense, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2018 Feb; Vol. 44 (2), pp. 172-184. Date of Electronic Publication: 2017 Jun 28.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Brain Neoplasms/*metabolism
    Glioblastoma/*metabolism
    O(6)-Methylguanine-DNA Methyltransferase/*metabolism
    Aged ; Brain Neoplasms/genetics ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Female ; Glioblastoma/genetics ; Glioblastoma/mortality ; Glioblastoma/pathology ; Humans ; Male ; Middle Aged ; O(6)-Methylguanine-DNA Methyltransferase/genetics ; Prognosis ; Survival Rate
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value.
    Autorzy:
    Rosager AM; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Hansen S; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Schonberg DL; Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic, Cleveland, United States of America.
    Rich JN; Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic, Cleveland, United States of America.
    Lathia JD; Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, United States of America.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    PloS one [PLoS One] 2017 Aug 24; Vol. 12 (8), pp. e0182954. Date of Electronic Publication: 2017 Aug 24 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antigens, CD/*metabolism
    Apoferritins/*metabolism
    Astrocytoma/*metabolism
    Brain Neoplasms/*metabolism
    Receptors, Transferrin/*metabolism
    Astrocytoma/pathology ; Brain/metabolism ; Brain Neoplasms/pathology ; Child, Preschool ; Cohort Studies ; Female ; Fluorescent Antibody Technique ; Humans ; Infant ; Male ; Prognosis ; Survival Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    APNG as a prognostic marker in patients with glioblastoma.
    Autorzy:
    Fosmark S; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Hellwege S; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Jensen KL; DAKO Denmark A/S, Glostrup, Denmark.
    Derand H; DAKO Denmark A/S, Glostrup, Denmark.
    Lohse J; DAKO Denmark A/S, Glostrup, Denmark.
    Sørensen MD; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
    Hansen S; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
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    Źródło:
    PloS one [PLoS One] 2017 Jun 29; Vol. 12 (6), pp. e0178693. Date of Electronic Publication: 2017 Jun 29 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Biomarkers, Tumor/*metabolism
    Brain Neoplasms/*pathology
    DNA Glycosylases/*metabolism
    Glioblastoma/*pathology
    Aged ; Brain Neoplasms/enzymology ; DNA Glycosylases/genetics ; Databases, Genetic ; Female ; Glioblastoma/enzymology ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Prognosis ; Survival Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype.
    Autorzy:
    Munthe S; Department of Pathology, Odense University Hospital, 5000 Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, 5000 Odense C, Denmark.; Department of Neurosurgery, Odense University Hospital, 5000 Odense C, Denmark.
    Petterson SA; Department of Pathology, Odense University Hospital, 5000 Odense C, Denmark.
    Dahlrot RH; Department of Oncology, Odense University Hospital, 5000 Odense C, Denmark.
    Poulsen FR; Institute of Clinical Research, University of Southern Denmark, 5000 Odense C, Denmark.; Department of Neurosurgery, Odense University Hospital, 5000 Odense C, Denmark.
    Hansen S; Institute of Clinical Research, University of Southern Denmark, 5000 Odense C, Denmark.; Department of Oncology, Odense University Hospital, 5000 Odense C, Denmark.
    Kristensen BW; Department of Pathology, Odense University Hospital, 5000 Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, 5000 Odense C, Denmark.
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    Źródło:
    PloS one [PLoS One] 2016 May 12; Vol. 11 (5), pp. e0155106. Date of Electronic Publication: 2016 May 12 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Brain Neoplasms/*pathology
    Glioma/*pathology
    Neoplastic Stem Cells/*pathology
    Adult ; Aged ; Animals ; Female ; Fluorescent Antibody Technique ; Humans ; Immunohistochemistry ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Phenotype ; Spheroids, Cellular/pathology ; Xenograft Model Antitumor Assays
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan.
    Autorzy:
    Urup T; a Department of Radiation Biology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;; b Department of Oncology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;
    Dahlrot RH; c Department of Oncology , Odense University Hospital , Odense , Denmark ;
    Grunnet K; a Department of Radiation Biology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;; b Department of Oncology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;
    Christensen IJ; d Laboratory of Gastroenterology , University of Copenhagen, Hvidovre Hospital , Copenhagen , Denmark ;
    Michaelsen SR; a Department of Radiation Biology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;
    Toft A; a Department of Radiation Biology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;
    Larsen VA; e Department of Radiology , Center of Diagnostic Investigation, Rigshospitalet , Copenhagen , Denmark ;
    Broholm H; f Department of Neuropathology , Center of Diagnostic Investigation, Rigshospitalet , Copenhagen , Denmark ;
    Kosteljanetz M; g Department of Neurosurgery , the Neurocenter, Rigshospitalet , Copenhagen , Denmark ;
    Hansen S; c Department of Oncology , Odense University Hospital , Odense , Denmark ;
    Poulsen HS; a Department of Radiation Biology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;; b Department of Oncology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;
    Lassen U; a Department of Radiation Biology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;; b Department of Oncology , the Finsen Center, Rigshospitalet , Copenhagen , Denmark ;; h Phase I Unit, Finsencenter, Rigshospitalet , Copenhagen , Denmark.
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    Źródło:
    Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2016; Vol. 55 (4), pp. 418-22. Date of Electronic Publication: 2016 Feb 01.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Models, Biological*
    Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
    Brain Neoplasms/*drug therapy
    Glioblastoma/*drug therapy
    Adult ; Aged ; Bevacizumab/administration & dosage ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Camptothecin/administration & dosage ; Camptothecin/analogs & derivatives ; Cohort Studies ; Disease-Free Survival ; Female ; Follow-Up Studies ; Glioblastoma/mortality ; Glioblastoma/pathology ; Humans ; Irinotecan ; Male ; Middle Aged ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Retrospective Studies ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Trends in tumors in the central nervous system in elderly in Denmark, 2008-2012.
    Autorzy:
    Dahlrot RH; a Department of Oncology , Odense University Hospital, Institute of Clinical Research, University of Southern Denmark , Odense , Denmark ;
    Poulsen FR; b Department of Neurosurgery , Odense University Hospital, Institute of Clinical Research, University of Southern Denmark , Odense , Denmark ;
    Nguyen NN; c Department of Radiology , Odense University Hospital, Institute of Clinical Research, University of Southern Denmark , Odense , Denmark ;
    Kristensen BW; d Department of Pathology , Odense University Hospital, Institute of Clinical Research, University of Southern Denmark , Odense , Denmark ;
    Hansen S; a Department of Oncology , Odense University Hospital, Institute of Clinical Research, University of Southern Denmark , Odense , Denmark ;
    Holm NV; a Department of Oncology , Odense University Hospital, Institute of Clinical Research, University of Southern Denmark , Odense , Denmark ;; e The Danish Twin Registry, University of Southern Denmark , Denmark.
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    Corporate Authors:
    Academy of Geriatric Cancer Research (AgeCare)
    Źródło:
    Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2016; Vol. 55 Suppl 1, pp. 91-7. Date of Electronic Publication: 2016 Jan 19.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Central Nervous System Neoplasms/*epidemiology
    Age Distribution ; Aged ; Aged, 80 and over ; Central Nervous System Neoplasms/mortality ; Central Nervous System Neoplasms/pathology ; Denmark/epidemiology ; Glioma/epidemiology ; Humans ; Incidence ; Male ; Prevalence ; Prognosis ; Registries ; Survival Rate
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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