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Tytuł :
Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Autorzy :
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Colombo MV; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Arrigoni C; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Bardinet V; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.
Saucier D; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Amatruda JF; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.; Children's Hospital of Los Angeles, Los Angeles, CA, USA.
Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.
Henssen AG; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), partner site, Berlin, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), partner site, Munich, Germany.
Moretti M; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany. .; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. .; German Cancer Consortium (DKTK), partner site, Munich, Germany. .; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 23; Vol. 11 (1), pp. 6068. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Published Erratum
Tytuł :
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Autorzy :
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Colombo MV; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Arrigoni C; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Bardinet V; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.
Saucier D; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Amatruda JF; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.; Children's Hospital of Los Angeles, Los Angeles, CA, USA.
Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.
Henssen AG; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), partner site, Berlin, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), partner site, Munich, Germany.
Moretti M; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany. .; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. .; German Cancer Consortium (DKTK), partner site, Munich, Germany. .; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 May 15; Vol. 11 (1), pp. 2423. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Oxidative Stress*
Oncogene Proteins, Fusion/*metabolism
Sarcoma, Ewing/*pathology
Adult ; Animals ; Bone Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation ; Child ; Chondrocytes/metabolism ; DNA Methylation ; Enhancer Elements, Genetic ; Gene Expression Profiling ; HEK293 Cells ; Humans ; Hydrazines/chemistry ; Mesenchymal Stem Cells/metabolism ; Mice ; Microsatellite Repeats ; Mitochondria/metabolism ; Oligonucleotide Array Sequence Analysis ; Oncogenes ; RNA Interference ; SOXD Transcription Factors/metabolism ; Sarcoma/genetics
Czasopismo naukowe
Tytuł :
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.
Autorzy :
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Department of Pediatrics, University Hospital Münster, 48149 Münster, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Paul T; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Surdez D; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, 75248 Paris, France.
Delattre O; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, 75248 Paris, France.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Kasan M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Henssen AG; Department of Pediatric Hematology/Oncology/BMT, Charité-University Medicine Berlin, 13353 Berlin, Germany.; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, 13125 Berlin, Germany.
Özen Ö; Department of Pathology, Başkent University Hospital, 06490 Ankara, Turkey.
Sugita S; Department of Surgical Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Hasegawa T; Department of Surgical Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Kanaseki T; Department of Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Bertram S; Institute of Pathology, University Hospital Essen, 45147 Essen, Germany.
Dirksen U; Pediatrics III, AYA Unit, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.; German Cancer Consortium (DKTK), Partner site Essen, 45147 Essen, Germany.
Hartmann W; Division of Translational Oncology, Gerhard-Domagk-Institute for Pathology, University Hospital Münster, 48149 Münster, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; German Cancer Consortium (DKTK), Partner site Munich, 80336 Munich, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; German Cancer Consortium (DKTK), Partner site Munich, 80336 Munich, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2020 Mar 10; Vol. 12 (3). Date of Electronic Publication: 2020 Mar 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.
Autorzy :
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Aynaud MM; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Mirabeau O; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
Mazor G; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Varon M; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Grossetête S; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
Gartlgruber M; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Surdez D; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Westermann F; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hartmann W; Division of Translational Pathology, Gerhard-Domagk Institute of Pathology, University Hospital of Münster, Münster, Germany.
Dirksen U; Department of Pediatric Hematology and Oncology, University Hospital of Essen, Essen, Germany.
Gymrek M; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.; Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA, USA.
Anderson ND; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Shlien A; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Rotblat B; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner site Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Delattre O; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; German Cancer Consortium (DKTK), Partner site Munich, Munich, Germany. .; German Cancer Research Center (DKFZ), Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2019 Sep 11; Vol. 10 (1), pp. 4128. Date of Electronic Publication: 2019 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Germ-Line Mutation/*genetics
Neoplasms/*genetics
Neoplasms/*therapy
Animals ; Cell Cycle Proteins ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; Cyclin-Dependent Kinase 2/antagonists & inhibitors ; Cyclin-Dependent Kinase 2/metabolism ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Mice ; Microsatellite Repeats/genetics ; Neoplasm Proteins/metabolism ; Oncogene Proteins, Fusion/metabolism ; Phenotype ; Polymorphism, Genetic ; Trans-Activators ; Treatment Outcome ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma.
Autorzy :
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knösel T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Altendorf-Hofmann A; Department of General, Visceral and Vascular Surgery, Jena University Hospital, Jena, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Alba-Rubio R; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Wehweck F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Hakozaki M; Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Dandekar T; Functional Genomics and Systems Biology Group, Department of Bioinformatics, Biocenter, Am Hubland, Würzburg, Germany.
Butt E; Institute for Experimental Biomedicine II, University Clinic of Würzburg, Würzburg, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Źródło :
International journal of cancer [Int J Cancer] 2019 Feb 15; Vol. 144 (4), pp. 859-867. Date of Electronic Publication: 2018 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
AMP Deaminase/*genetics
Biomarkers, Tumor/*genetics
Genomics/*methods
Histiocytoma, Malignant Fibrous/*genetics
AMP Deaminase/metabolism ; Adult ; Aged ; Aged, 80 and over ; Animals ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Histiocytoma, Malignant Fibrous/metabolism ; Histiocytoma, Malignant Fibrous/pathology ; Humans ; Kaplan-Meier Estimate ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Middle Aged ; Prognosis ; RNAi Therapeutics/methods ; Xenograft Model Antitumor Assays/methods ; Young Adult
Czasopismo naukowe
Tytuł :
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma.
Autorzy :
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Alba Rubio R; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.; Institute of Pathology of the LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.; Institute of Pathology of the LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Kirchner T; Institute of Pathology of the LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bach H; Department of Medicine, Division of Infectious Diseases, and IIRC Antibody Engineering and Proteomics facility, University of British Columbia, Vancouver, BC, Canada.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany. .; Institute of Pathology of the LMU Munich, Munich, Germany. .; German Cancer Consortium (DKTK), Heidelberg, Germany. .; German Cancer Research Center (DKFZ), Heidelberg, Germany. .
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Źródło :
Cell death & disease [Cell Death Dis] 2019 Feb 11; Vol. 10 (2), pp. 116. Date of Electronic Publication: 2019 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcitonin Gene-Related Peptide/*metabolism
Receptor Activity-Modifying Protein 1/*metabolism
Sarcoma, Ewing/*pathology
Animals ; Calcitonin Gene-Related Peptide/antagonists & inhibitors ; Calcitonin Gene-Related Peptide/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Inbred NOD ; Microsatellite Repeats/genetics ; RNA Interference ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/therapeutic use ; Receptor Activity-Modifying Protein 1/antagonists & inhibitors ; Receptor Activity-Modifying Protein 1/genetics ; Sarcoma, Ewing/drug therapy ; Sarcoma, Ewing/metabolism ; Small Molecule Libraries/pharmacology ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł :
Systematic identification of cancer-specific MHC-binding peptides with RAVEN.
Autorzy :
Baldauf MC; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Gerke JS; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Kirschner A; Children's Cancer Research Center, Technische Universität München (TUM), Munich, Germany.
Blaeschke F; Department of Pediatrics, Dr. von Hauner'sches Children's Hospital, LMU Munich, Munich, Germany.
Effenberger M; Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Schober K; Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Rubio RA; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Kanaseki T; Department of Pathology, Sapporo Medical University, Sapporo, Japan.
Kiran MM; Department of Pathology, Medical Faculty, Yildirim Beyazit University, Ankara, Turkey.
Dallmayer M; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Musa J; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Akpolat N; Department of Pathology, Turgut Ozal Medical Center, Inonu University, Malatya, Turkey.
Akatli AN; Department of Pathology, Turgut Ozal Medical Center, Inonu University, Malatya, Turkey.
Rosman FC; Department for Pathology, Hospital Municipal Jesus, Rio de Janeiro, Brazil.
Özen Ö; Department of Pathology, Medical Faculty, Başkent University Hospital, Ankara, Turkey.
Sugita S; Department of Pathology, Sapporo Medical University, Sapporo, Japan.
Hasegawa T; Department of Pathology, Sapporo Medical University, Sapporo, Japan.
Sugimura H; Department of Tumor Pathology, Hamamatsu School of Medicine, Hamamatsu, Japan.
Baumhoer D; Bone Tumor Reference Center, Institute of Pathology of the University Hospital of Basel, Basel, Switzerland.
Knott MML; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Sannino G; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Marchetto A; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Li J; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Busch DH; Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Feuchtinger T; Department of Pediatrics, Dr. von Hauner'sches Children's Hospital, LMU Munich, Munich, Germany.
Ohmura S; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Orth MF; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.
Thiel U; Children's Cancer Research Center, Technische Universität München (TUM), Munich, Germany.
Kirchner T; Faculty of Medicine, Institute of Pathology, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Grünewald TGP; Faculty of Medicine, Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, LMU Munich, Munich, Germany.; Faculty of Medicine, Institute of Pathology, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Źródło :
Oncoimmunology [Oncoimmunology] 2018 Jul 23; Vol. 7 (9), pp. e1481558. Date of Electronic Publication: 2018 Jul 23 (Print Publication: 2018).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas?
Autorzy :
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baumhoer D; Bone Tumour Reference Center, Institute of Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.
de Alava E; Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, CIBERONC, Seville, Spain.
Hartmann W; Gerhard-Domagk-Institute for Pathology, University Hospital Münster, Westfalian Wilhelms University, Münster, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; German Cancer Consortium (DKTK), Heidelberg, Germany. .; German Cancer Research Center (DKFZ), Heidelberg, Germany. .
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Źródło :
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2018 Jun; Vol. 31 (6), pp. 997-999. Date of Electronic Publication: 2018 Jun 12.
Typ publikacji :
Letter; Comment
MeSH Terms :
NFATC Transcription Factors*
Sarcoma, Ewing*
Humans ; PAX7 Transcription Factor ; RNA-Binding Protein EWS
Opinia redakcyjna

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