Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures.
Autorzy:
Bradshaw DV Jr; Graduate Program in Neuroscience, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA. Knutsen AK; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. Korotcov A; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. Sullivan GM; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA. Radomski KL; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. DardzinskiBJ; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for Scientific Review, National Institutes of Health, Bethesda, MD, USA. Zi X; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA. McDaniel DP; Biomedical Instrumentation Center, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. Armstrong RC; Graduate Program in Neuroscience, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA. .; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .
Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits.
Autorzy:
Sullivan GM; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA. Knutsen AK; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. Peruzzotti-Jametti L; Department of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK. Korotcov A; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. Bosomtwi A; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. DardzinskiBJ; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. Bernstock JD; Department of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK.; Present address: Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Rizzi S; Genomics, Stem Cell Biology and Regenerative Medicine & CMBI, Leopold-Franzens-University Innsbruck, Innsbruck, Austria. Edenhofer F; Genomics, Stem Cell Biology and Regenerative Medicine & CMBI, Leopold-Franzens-University Innsbruck, Innsbruck, Austria. Pluchino S; Department of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK. Armstrong RC; Department of Anatomy, Physiology and Genetics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA. .; Center for Neuroscience and Regenerative Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .
Chronic Exposure to High Altitude: Synaptic, Astroglial and Memory Changes.
Autorzy:
Sharma R; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Cramer NP; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Department of Anatomy, Physiology and Genetics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Perry B; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Adahman Z; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Murphy EK; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Xu X; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Department of Anatomy, Physiology and Genetics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. DardzinskiBJ; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Department of Radiology and Radiological Sciences, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Galdzicki Z; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Department of Anatomy, Physiology and Genetics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Perl DP; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Dickstein DL; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA.; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. Iacono D; Department of Pathology, F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. .; Center for Neuroscience and Regenerative Medicine (CNRM), F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. .; Department of Neurology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences (USU), Bethesda, MD, USA. .; Neurodegenerative Clinics, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD, USA. .; The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, MD, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Nov 11; Vol. 9 (1), pp. 16406. Date of Electronic Publication: 2019 Nov 11.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
Brugia malayi infection in ferrets - A small mammal model of lymphatic filariasis.
Autorzy:
Jackson-Thompson BM; Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America. Kim SY; Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America. Jaiswal S; Department of Radiology and Radiological Science, Uniformed Services University, Bethesda, Maryland, United States of America. Scott JR; Department of Radiology and Radiological Science, Uniformed Services University, Bethesda, Maryland, United States of America. Jones SR; Navy Medicine East (M3), Portsmouth, Virginia, United States of America. Morris CP; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United Sates of America. Fite JJ; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United Sates of America. Laurie K; WHO Collaborating Centre for Reference and Research on Influenza at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. Hoy AR; Department of Radiology and Radiological Science, Uniformed Services University, Bethesda, Maryland, United States of America. DardzinskiBJ; Department of Radiology and Radiological Science, Uniformed Services University, Bethesda, Maryland, United States of America. Mitre E; Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Mar 30; Vol. 12 (3), pp. e0006334. Date of Electronic Publication: 2018 Mar 30 (Print Publication: 2018).
Magnetic resonance imaging of the hand and wrist in a randomized, double-blind, multicenter, placebo-controlled trial of infliximab for rheumatoid arthritis: Comparison of dynamic contrast enhanced assessments with semi-quantitative scoring.
Autorzy:
Beals C; Department of Clinical Research, Merck & Co., Inc., Kenilworth, New Jersey, United States of America. Baumgartner R; Department of Clinical Research, Merck & Co., Inc., Kenilworth, New Jersey, United States of America. Peterfy C; Spire Sciences, Inc., Boca Raton, Florida, United States of America. Balanescu A; Department of Immunology, U of Med and Pharm Carol Davila, Bucharest, Romania. Mirea G; Department of Rheumatology, Tractorul County Hospital, Brasov, Romania. Harabagiu A; German Diagnostic Center, Chisinau, MD, Moldova. Popa S; Department of Rheumatology, Republican Clinical Hospital, Chisinau, MD, Moldova. Cheng A; Department of Clinical Research, Merck & Co., Inc., Kenilworth, New Jersey, United States of America. Feng D; Department of Clinical Research, Merck & Co., Inc., Kenilworth, New Jersey, United States of America. Ashton E; VirtualScopics, Rochester, New York, United States of America. DiCarlo J; Spire Sciences, Inc., Boca Raton, Florida, United States of America. Vallee MH; Department of Clinical Research, Merck & Co., Inc., Kenilworth, New Jersey, United States of America. DardzinskiBJ; Department of Clinical Research, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Dec 13; Vol. 12 (12), pp. e0187397. Date of Electronic Publication: 2017 Dec 13 (Print Publication: 2017).
Effects of isoflurane anesthesia and intravenous morphine self-administration on regional glucose metabolism ([ F]FDG-PET) of male Sprague-Dawley rats.
Autorzy:
Park TY; Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Nishida KS; Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Wilson CM; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Radiology, University of New Mexico, Albuquerque, NM, USA. Jaiswal S; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Scott J; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Hoy AR; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Selwyn RG; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Radiology, University of New Mexico, Albuquerque, NM, USA.; Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. DardzinskiBJ; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Choi KH; Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Graduate School of Nursing, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
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