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Wyświetlanie 1-62 z 62
Tytuł:
RNA polymerase motions during promoter melting.
Autorzy:
Feklistov A; The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA. .
Bae B; The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
Hauver J; The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
Lass-Napiorkowska A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, USA.
Kalesse M; Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124 Brunswick, Germany.
Glaus F; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Vladimir-Prelog-Weg 1-5/10 8093 Zürich, Switzerland.
Altmann KH; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Vladimir-Prelog-Weg 1-5/10 8093 Zürich, Switzerland.
Heyduk T; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, USA.
Landick R; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Darst SA; The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2017 May 26; Vol. 356 (6340), pp. 863-866.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Movement*
DNA-Directed RNA Polymerases/*chemistry
DNA-Directed RNA Polymerases/*metabolism
Promoter Regions, Genetic/*genetics
Bacteria/enzymology ; Catalytic Domain ; Crystallization ; DNA/chemistry ; DNA/metabolism ; Genes, Reporter ; Kinetics ; Ligands ; Models, Molecular ; Nucleic Acid Conformation ; Nucleic Acid Denaturation ; Rotation ; Static Electricity ; Templates, Genetic
Czasopismo naukowe
Tytuł:
TFIIB is only ∼9 Å away from the 5'-end of a trimeric RNA primer in a functional RNA polymerase II preinitiation complex.
Autorzy:
Bick MJ; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY, United States of America.
Malik S; Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, NY, United States of America.
Mustaev A; Department of Chemistry and Environmental Sciences, New Jersey Institute of Technology, University Heights, Newark, NJ, United States of America.
Darst SA; Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Mar 16; Vol. 10 (3), pp. e0119007. Date of Electronic Publication: 2015 Mar 16 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Bacteria/*metabolism
Eukaryotic Cells/*metabolism
RNA/*metabolism
RNA Polymerase II/*metabolism
Transcription Factor TFIIB/*metabolism
Catalytic Domain ; Models, Molecular ; Promoter Regions, Genetic ; RNA/chemistry ; RNA Polymerase II/chemistry ; Sigma Factor/chemistry ; Sigma Factor/metabolism ; Transcription Factor TFIIB/chemistry ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
RNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movement.
Autorzy:
Hein PP; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Kolb KE; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Windgassen T; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Bellecourt MJ; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Darst SA; Laboratory of Molecular Biophysics, Rockefeller University, New York, New York, USA.
Mooney RA; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Landick R; 1] Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
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Źródło:
Nature structural & molecular biology [Nat Struct Mol Biol] 2014 Sep; Vol. 21 (9), pp. 794-802. Date of Electronic Publication: 2014 Aug 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
DNA-Directed RNA Polymerases/*metabolism
Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
RNA/*metabolism
Amino Acid Sequence ; Base Sequence ; Catalytic Domain ; DNA-Directed RNA Polymerases/chemistry ; Escherichia coli/chemistry ; Escherichia coli Proteins/chemistry ; Models, Molecular ; Molecular Sequence Data ; Nucleic Acid Conformation ; Protein Conformation ; RNA/chemistry ; RNA Folding
Czasopismo naukowe
Tytuł:
Promoter melting by an alternative σ, one base at a time.
Autorzy:
Darst SA; Rockefeller University, New York, New York, USA.
Feklistov A; Rockefeller University, New York, New York, USA.
Gross CA; Department of Microbiology and Immunology, the California Institute of Quantitative Biology and the Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, California, USA.
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Źródło:
Nature structural & molecular biology [Nat Struct Mol Biol] 2014 Apr; Vol. 21 (4), pp. 350-1.
Typ publikacji:
News; Research Support, N.I.H., Extramural; Comment
MeSH Terms:
Promoter Regions, Genetic*
Sigma Factor/*genetics
Humans
Periodyk
Tytuł:
RNA-Seq reveals differential gene expression in Staphylococcus aureus with single-nucleotide resolution.
Autorzy:
Osmundson J; Laboratory of Molecular Biophysics, the Rockefeller University, New York, New York, United States of America.
Dewell S
Darst SA
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Źródło:
PloS one [PLoS One] 2013 Oct 07; Vol. 8 (10), pp. e76572. Date of Electronic Publication: 2013 Oct 07 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Gene Expression Regulation, Bacterial*
Polymorphism, Single Nucleotide*
Gene Expression Profiling/*methods
Sequence Analysis, RNA/*methods
Staphylococcus aureus/*genetics
Base Sequence ; Genome, Bacterial/genetics ; Humans ; Inverted Repeat Sequences/genetics ; Mutation ; Oligonucleotide Array Sequence Analysis ; Reproducibility of Results ; Species Specificity ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/classification ; Transcription Factors/genetics ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł:
Initiation of transcription-coupled repair characterized at single-molecule resolution.
Autorzy:
Howan K; Institut Jacques Monod, CNRS, UMR 7592, University Paris Diderot, Sorbonne Paris Cité F-75205 Paris, France.
Smith AJ
Westblade LF
Joly N
Grange W
Zorman S
Darst SA
Savery NJ
Strick TR
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Źródło:
Nature [Nature] 2012 Oct 18; Vol. 490 (7420), pp. 431-4. Date of Electronic Publication: 2012 Sep 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Repair*
Transcription, Genetic*
Bacterial Proteins/*metabolism
Transcription Factors/*metabolism
Adenosine Triphosphate/metabolism ; Biocatalysis ; DNA Damage ; DNA-Directed RNA Polymerases/metabolism ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Hydrolysis ; Kinetics ; Promoter Regions, Genetic/genetics ; Pyrimidine Dimers/chemistry ; Pyrimidine Dimers/metabolism ; Transcription Elongation, Genetic ; Transcription Initiation, Genetic ; Transcription Termination, Genetic
Czasopismo naukowe
Tytuł:
Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
Autorzy:
Opalka N; The Rockefeller University, New York, New York, USA.
Brown J
Lane WJ
Twist KA
Landick R
Asturias FJ
Darst SA
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Źródło:
PLoS biology [PLoS Biol] 2010 Sep 14; Vol. 8 (9). Date of Electronic Publication: 2010 Sep 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Molecular*
DNA-Directed RNA Polymerases/*chemistry
Escherichia coli/*enzymology
Amino Acid Sequence ; Cryoelectron Microscopy ; Crystallography, X-Ray ; Molecular Sequence Data ; Protein Conformation ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł:
Climate change and the integrity of science.
Autorzy:
Gleick PH
Adams RM
Amasino RM
Anders E
Anderson DJ
Anderson WW
Anselin LE
Arroyo MK
Asfaw B
Ayala FJ
Bax A
Bebbington AJ
Bell G
Bennett MV
Bennetzen JL
Berenbaum MR
Berlin OB
Bjorkman PJ
Blackburn E
Blamont JE
Botchan MR
Boyer JS
Boyle EA
Branton D
Briggs SP
Briggs WR
Brill WJ
Britten RJ
Broecker WS
Brown JH
Brown PO
Brunger AT
Cairns J Jr
Canfield DE
Carpenter SR
Carrington JC
Cashmore AR
Castilla JC
Cazenave A
Chapin FS 3rd
Ciechanover AJ
Clapham DE
Clark WC
Clayton RN
Coe MD
Conwell EM
Cowling EB
Cowling RM
Cox CS
Croteau RB
Crothers DM
Crutzen PJ
Daily GC
Dalrymple GB
Dangl JL
Darst SA
Davies DR
Davis MB
De Camilli PV
Dean C
DeFries RS
Deisenhofer J
Delmer DP
DeLong EF
DeRosier DJ
Diener TO
Dirzo R
Dixon JE
Donoghue MJ
Doolittle RF
Dunne T
Ehrlich PR
Eisenstadt SN
Eisner T
Emanuel KA
Englander SW
Ernst WG
Falkowski PG
Feher G
Ferejohn JA
Fersht A
Fischer EH
Fischer R
Flannery KV
Frank J
Frey PA
Fridovich I
Frieden C
Futuyma DJ
Gardner WR
Garrett CJ
Gilbert W
Goldberg RB
Goodenough WH
Goodman CS
Goodman M
Greengard P
Hake S
Hammel G
Hanson S
Harrison SC
Hart SR
Hartl DL
Haselkorn R
Hawkes K
Hayes JM
Hille B
Hökfelt T
House JS
Hout M
Hunten DM
Izquierdo IA
Jagendorf AT
Janzen DH
Jeanloz R
Jencks CS
Jury WA
Kaback HR
Kailath T
Kay P
Kay SA
Kennedy D
Kerr A
Kessler RC
Khush GS
Kieffer SW
Kirch PV
Kirk K
Kivelson MG
Klinman JP
Klug A
Knopoff L
Kornberg H
Kutzbach JE
Lagarias JC
Lambeck K
Landy A
Langmuir CH
Larkins BA
Le Pichon XT
Lenski RE
Leopold EB
Levin SA
Levitt M
Likens GE
Lippincott-Schwartz J
Lorand L
Lovejoy CO
Lynch M
Mabogunje AL
Malone TF
Manabe S
Marcus J
Massey DS
McWilliams JC
Medina E
Melosh HJ
Meltzer DJ
Michener CD
Miles EL
Mooney HA
Moore PB
Morel FM
Mosley-Thompson ES
Moss B
Munk WH
Myers N
Nair GB
Nathans J
Nester EW
Nicoll RA
Novick RP
O'Connell JF
Olsen PE
Opdyke ND
Oster GF
Ostrom E
Pace NR
Paine RT
Palmiter RD
Pedlosky J
Petsko GA
Pettengill GH
Philander SG
Piperno DR
Pollard TD
Price PB Jr
Reichard PA
Reskin BF
Ricklefs RE
Rivest RL
Roberts JD
Romney AK
Rossmann MG
Russell DW
Rutter WJ
Sabloff JA
Sagdeev RZ
Sahlins MD
Salmond A
Sanes JR
Schekman R
Schellnhuber J
Schindler DW
Schmitt J
Schneider SH
Schramm VL
Sederoff RR
Shatz CJ
Sherman F
Sidman RL
Sieh K
Simons EL
Singer BH
Singer MF
Skyrms B
Sleep NH
Smith BD
Snyder SH
Sokal RR
Spencer CS
Steitz TA
Strier KB
Südhof TC
Taylor SS
Terborgh J
Thomas DH
Thompson LG
Tjian RT
Turner MG
Uyeda S
Valentine JW
Valentine JS
Van Etten JL
van Holde KE
Vaughan M
Verba S
von Hippel PH
Wake DB
Walker A
Walker JE
Watson EB
Watson PJ
Weigel D
Wessler SR
West-Eberhard MJ
White TD
Wilson WJ
Wolfenden RV
Wood JA
Woodwell GM
Wright HE Jr
Wu C
Wunsch C
Zoback ML
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Źródło:
Science (New York, N.Y.) [Science] 2010 May 07; Vol. 328 (5979), pp. 689-90.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Climate Change*
Politics ; Public Policy ; Research/standards ; Research Personnel
Raport
Tytuł:
The structural basis for promoter -35 element recognition by the group IV sigma factors.
Autorzy:
Lane WJ; The Rockefeller University, New York, New York, United States of America.
Darst SA
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Źródło:
PLoS biology [PLoS Biol] 2006 Sep; Vol. 4 (9), pp. e269.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Promoter Regions, Genetic*
Regulatory Elements, Transcriptional/*physiology
Sigma Factor/*chemistry
Amino Acid Sequence ; Base Sequence ; Binding Sites ; Crystallization ; DNA-Binding Proteins/chemistry ; DNA-Directed RNA Polymerases/chemistry ; Escherichia coli ; Escherichia coli Proteins/chemistry ; Gene Expression Regulation, Bacterial ; Models, Biological ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Sequence Homology, Amino Acid ; Sequence Homology, Nucleic Acid
Czasopismo naukowe
    Wyświetlanie 1-62 z 62

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