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    Tytuł:
    Reinforcement learning for intensive care medicine: actionable clinical insights from novel approaches to reward shaping and off-policy model evaluation.
    Autorzy:
    Roggeveen LF; Department of Intensive Care Medicine, Center for Critical Care Computational Intelligence (C4I), Amsterdam Medical Data Science (AMDS), Amsterdam Cardiovascular Science (ACS), Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam Public Health (APH), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.; Quantitative Data Analytics Group, Department of Computer Science, Faculty of Science, Vrije Universiteit, Amsterdam, The Netherlands.
    Hassouni AE; Quantitative Data Analytics Group, Department of Computer Science, Faculty of Science, Vrije Universiteit, Amsterdam, The Netherlands.
    de Grooth HJ; Department of Intensive Care Medicine, Center for Critical Care Computational Intelligence (C4I), Amsterdam Medical Data Science (AMDS), Amsterdam Cardiovascular Science (ACS), Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam Public Health (APH), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Girbes ARJ; Department of Intensive Care Medicine, Center for Critical Care Computational Intelligence (C4I), Amsterdam Medical Data Science (AMDS), Amsterdam Cardiovascular Science (ACS), Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam Public Health (APH), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Hoogendoorn M; Quantitative Data Analytics Group, Department of Computer Science, Faculty of Science, Vrije Universiteit, Amsterdam, The Netherlands.
    Elbers PWG; Department of Intensive Care Medicine, Center for Critical Care Computational Intelligence (C4I), Amsterdam Medical Data Science (AMDS), Amsterdam Cardiovascular Science (ACS), Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam Public Health (APH), Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands. .
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    Corporate Authors:
    Dutch ICU Data Sharing Against COVID-19 Collaborators
    Źródło:
    Intensive care medicine experimental [Intensive Care Med Exp] 2024 Mar 25; Vol. 12 (1), pp. 32. Date of Electronic Publication: 2024 Mar 25.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effect of lung ultrasound-guided fluid deresuscitation on duration of ventilation in intensive care unit patients (CONFIDENCE): protocol for a multicentre randomised controlled trial.
    Autorzy:
    Blok SG; Department of Intensive Care, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands. .; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Amsterdam, The Netherlands. .; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Leiden, The Netherlands. .
    Mousa A; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Amsterdam, The Netherlands.; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Leiden, The Netherlands.; Department of Intensive Care, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
    Brouwer MG; Department of Intensive Care, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands.; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Amsterdam, The Netherlands.; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Leiden, The Netherlands.
    de Grooth HJ; Department of Intensive Care, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
    Neto AS; Department of Critical Care Medicine, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.; Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, Melbourne, Australia.; Department of Intensive Care, Austin Hospital, Melbourne, Australia.
    Blans MJ; Department of Intensive Care, Rijnstate Hospital, Arnhem, Netherlands.
    den Boer S; Department of Intensive Care, Spaarne Gasthuis, Haarlem, Hoofddorp, Netherlands.
    Dormans T; Department of Intensive Care, Zuyderland Medical Centre, Heerlen, Netherlands.; Department of Intensive Care, Zuyderland Medical Centre, Sittard-Geleen, Netherlands.
    Endeman H; Department of Intensive Care, Erasmus MC, Rotterdam, Netherlands.
    Roeleveld T; Department of Intensive Care, Amstelland Hospital, Amstelveen, Netherlands.
    Scholten H; Department of Intensive Care, Catharina Hospital, Eindhoven, Netherlands.
    van Slobbe-Bijlsma ER; Department of Intensive Care, TerGooi MC, Hilversum, Netherlands.
    Scholten E; Department of Intensive Care, St. Antonius Hospital, Nieuwegein, Utrecht, Netherlands.
    Touw H; Department of Intensive Care, Radboud University Medical Centre, Nijmegen, Netherlands.
    van der Ven FSLIM; Department of Intensive Care, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands.; Department of Intensive Care, Rode Kruis Hospital, Beverwijk, Netherlands.
    Wils EJ; Department of Intensive Care, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands.
    van Westerloo DJ; Department of Intensive Care, Leiden University Medical Centre, Leiden, Netherlands.
    Heunks LMA; Department of Intensive Care, Erasmus MC, Rotterdam, Netherlands.
    Schultz MJ; Department of Intensive Care, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands.
    Paulus F; Department of Intensive Care, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands.; Center of Expertise Urban Vitality, Faculty of Health, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
    Tuinman PR; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Amsterdam, The Netherlands.; Amsterdam Leiden Intensive care Focused Echography (ALIFE, www.alifeofpocus.com ), Leiden, The Netherlands.; Department of Intensive Care, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
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    Źródło:
    Trials [Trials] 2023 Mar 24; Vol. 24 (1), pp. 226. Date of Electronic Publication: 2023 Mar 24.
    Typ publikacji:
    Clinical Trial Protocol; Journal Article
    MeSH Terms:
    Critical Illness*
    Lung*/diagnostic imaging
    Adult ; Humans ; Critical Care/methods ; Respiration, Artificial/methods ; Intensive Care Units ; Ultrasonography, Interventional ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Development and validation of a multivariable model predicting the required catheter dwell time among mechanically ventilated critically ill patients in three randomized trials.
    Autorzy:
    Iachkine J; Department of Clinical Research and Biostatistics, Caen University Hospital and Caen Normandy University, Caen, France.; INSERM U1311 DYNAMICURE, Caen Normandy University, Caen, France.
    Buetti N; Infection Control Program and World Health Organization Collaborating Center on Patient Safety, Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.
    de Grooth HJ; Department of Intensive Care, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
    Briant AR; Department of Clinical Research and Biostatistics, Caen University Hospital and Caen Normandy University, Caen, France.
    Mimoz O; Inserm U1070, Poitiers University, Poitiers, France.; Poitiers University Hospital, 86021, Poitiers, France.
    Mégarbane B; Medical and Toxicological Intensive Care Unit, Lariboisière Hospital, AP-HP, INSERM, UMRS-1144, Paris University, Paris, France.
    Mira JP; Medical ICU, Cochin Hospital, AP-HP, 75014, Paris, France.
    Valette X; Department of Medical Intensive Care, Caen University Hospital, 14000, Caen, France.
    Daubin C; Department of Medical Intensive Care, Caen University Hospital, 14000, Caen, France.
    du Cheyron D; Department of Medical Intensive Care, Caen University Hospital, 14000, Caen, France.
    Mermel LA; Department of Epidemiology and Infection Prevention, Lifespan Hospital System, Providence, RI, USA.; Department of Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA.
    Timsit JF; Medical and Infectious Diseases ICU (MI2), Bichat Hospital, AP-HP, University of Paris, IAME, INSERM U1137, Paris, France.
    Parienti JJ; Department of Clinical Research and Biostatistics, Caen University Hospital and Caen Normandy University, Caen, France. .; INSERM U1311 DYNAMICURE, Caen Normandy University, Caen, France. .
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    Źródło:
    Annals of intensive care [Ann Intensive Care] 2023 Jan 16; Vol. 13 (1), pp. 5. Date of Electronic Publication: 2023 Jan 16.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Predicting responders to prone positioning in mechanically ventilated patients with COVID-19 using machine learning.
    Autorzy:
    Dam TA; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands. .
    Roggeveen LF; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    van Diggelen F; Quantitative Data Analytics Group, Department of Computer Science, Faculty of Science, VU University, Amsterdam, The Netherlands.
    Fleuren LM; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Jagesar AR; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Otten M; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    de Vries HJ; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Gommers D; Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands.
    Cremer OL; Intensive Care, UMC Utrecht, Utrecht, The Netherlands.
    Bosman RJ; ICU, OLVG, Amsterdam, The Netherlands.
    Rigter S; Department of Anesthesiology and Intensive Care, St. Antonius Hospital, Nieuwegein, The Netherlands.
    Wils EJ; Department of Intensive Care, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
    Frenzel T; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
    Dongelmans DA; Department of Intensive Care Medicine, Amsterdam UMC, Amsterdam, The Netherlands.
    de Jong R; Intensive Care, Bovenij Ziekenhuis, Amsterdam, The Netherlands.
    Peters MAA; Intensive Care, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
    Kamps MJA; Intensive Care, Catharina Ziekenhuis Eindhoven, Eindhoven, The Netherlands.
    Ramnarain D; Department of Intensive Care, ETZ Tilburg, Tilburg, The Netherlands.
    Nowitzky R; Intensive Care, HagaZiekenhuis, Den Haag, The Netherlands.
    Nooteboom FGCA; Intensive Care, Laurentius Ziekenhuis, Roermond, The Netherlands.
    de Ruijter W; Department of Intensive Care Medicine, Northwest Clinics, Alkmaar, The Netherlands.
    Urlings-Strop LC; Intensive Care, Reinier de Graaf Gasthuis, Delft, The Netherlands.
    Smit EGM; Intensive Care, Spaarne Gasthuis, Haarlem en Hoofddorp, The Netherlands.
    Mehagnoul-Schipper DJ; Intensive Care, VieCuri Medisch Centrum, Venlo, The Netherlands.
    Dormans T; Intensive Care, Zuyderland MC, Heerlen, The Netherlands.
    de Jager CPC; Department of Intensive Care, Jeroen Bosch Ziekenhuis, Den Bosch, The Netherlands.
    Hendriks SHA; Intensive Care, Albert Schweitzerziekenhuis, Dordrecht, The Netherlands.
    Achterberg S; ICU, Haaglanden Medisch Centrum, Den Haag, The Netherlands.
    Oostdijk E; ICU, Maasstad Ziekenhuis Rotterdam, Rotterdam, The Netherlands.
    Reidinga AC; ICU, SEH, BWC, Martiniziekenhuis, Groningen, The Netherlands.
    Festen-Spanjer B; Intensive Care, Ziekenhuis Gelderse Vallei, Ede, The Netherlands.
    Brunnekreef GB; Department of Intensive Care, Ziekenhuisgroep Twente, Almelo, The Netherlands.
    Cornet AD; Department of Intensive Care, Medisch Spectrum Twente, Enschede, The Netherlands.
    van den Tempel W; Department of Intensive Care, Ikazia Ziekenhuis Rotterdam, Rotterdam, The Netherlands.
    Boelens AD; Antonius Ziekenhuis Sneek, Sneek, The Netherlands.
    Koetsier P; Intensive Care, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.
    Lens J; ICU, IJsselland Ziekenhuis, Capelle aan den IJssel, The Netherlands.
    Faber HJ; ICU, WZA, Assen, The Netherlands.
    Karakus A; Department of Intensive Care, Diakonessenhuis Hospital, Utrecht, The Netherlands.
    Entjes R; Department of Intensive Care, Adrz, Goes, The Netherlands.
    de Jong P; Department of Anesthesia and Intensive Care, Slingeland Ziekenhuis, Doetinchem, The Netherlands.
    Rettig TCD; Department of Anesthesiology, Intensive Care and Pain Medicine, Amphia Ziekenhuis, Breda, The Netherlands.
    Arbous S; LUMC, Leiden, The Netherlands.
    Vonk SJJ; Pacmed, Amsterdam, The Netherlands.
    Machado T; Pacmed, Amsterdam, The Netherlands.
    Herter WE; Pacmed, Amsterdam, The Netherlands.
    de Grooth HJ; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Thoral PJ; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Girbes ARJ; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
    Hoogendoorn M; Quantitative Data Analytics Group, Department of Computer Science, Faculty of Science, VU University, Amsterdam, The Netherlands.
    Elbers PWG; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
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    Corporate Authors:
    Dutch ICU Data Sharing Against COVID-19 Collaborators
    Źródło:
    Annals of intensive care [Ann Intensive Care] 2022 Oct 20; Vol. 12 (1), pp. 99. Date of Electronic Publication: 2022 Oct 20.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Early high-dose vitamin C in post-cardiac arrest syndrome (VITaCCA): study protocol for a randomized, double-blind, multi-center, placebo-controlled trial.
    Autorzy:
    Rozemeijer S; Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
    de Grooth HJ; Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.; Department of Anesthesiology, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Elbers PWG; Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Girbes ARJ; Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    den Uil CA; Department of Intensive Care Medicine, Maasstad Hospital, Maasstadweg 21, 3079 DZ, Rotterdam, The Netherlands.
    Dubois EA; Department of Cardiology, Erasmus University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Intensive Care Medicine, Erasmus University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
    Wils EJ; Department of Intensive Care Medicine, Franciscus Gasthuis & Vlietland, Kleiweg 500, 3045 PM, Rotterdam, The Netherlands.
    Rettig TCD; Department of Anesthesiology, Intensive Care and Pain Medicine, Amphia Hospital, Molengracht 21, 4818 CK, Breda, The Netherlands.
    van Zanten ARH; Department of Intensive Care Medicine, Gelderse Vallei Hospital, Willy Brandtlaan 10, 6716 RP, Ede, The Netherlands.; Division of Human Nutrition and Health, Wageningen University & Research, HELIX (Building 124), Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
    Vink R; Department of Intensive Care Medicine, Tergooi Hospital, Van Riebeeckweg 212, 1213 XZ, Hilversum, The Netherlands.
    van den Bogaard B; Department of Intensive Care Medicine, OLVG, Oosterpark 9, 1091 AC, Amsterdam, The Netherlands.
    Bosman RJ; Department of Intensive Care Medicine, OLVG, Oosterpark 9, 1091 AC, Amsterdam, The Netherlands.
    Oudemans-van Straaten HM; Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    de Man AME; Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
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    Źródło:
    Trials [Trials] 2021 Aug 18; Vol. 22 (1), pp. 546. Date of Electronic Publication: 2021 Aug 18.
    Typ publikacji:
    Clinical Trial Protocol; Journal Article
    MeSH Terms:
    Post-Cardiac Arrest Syndrome*
    Humans ; Ascorbic Acid ; Double-Blind Method ; Multicenter Studies as Topic ; Organ Dysfunction Scores ; Randomized Controlled Trials as Topic ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Lung ultrasound and computed tomography to monitor COVID-19 pneumonia in critically ill patients: a two-center prospective cohort study.
    Autorzy:
    Heldeweg MLA; Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands. .; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam UMC, Amsterdam, The Netherlands. .; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands. .; VU University Medical Center Amsterdam, Postbox 7507, 1007 MB, Amsterdam, The Netherlands. .
    Lopez Matta JE; Department of Intensive Care Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
    Haaksma ME; Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
    Smit JM; Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
    Elzo Kraemer CV; Department of Intensive Care Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
    de Grooth HJ; Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.
    de Jonge E; Department of Intensive Care Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
    Meijboom LJ; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.
    Heunks LMA; Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.
    van Westerloo DJ; Department of Intensive Care Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
    Tuinman PR; Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.; Amsterdam Leiden Intensive Care Focused Echography (ALIFE), Amsterdam, The Netherlands.
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    Źródło:
    Intensive care medicine experimental [Intensive Care Med Exp] 2021 Jan 25; Vol. 9 (1), pp. 1. Date of Electronic Publication: 2021 Jan 25.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock - rationale and design of a multicenter randomized controlled superiority trial.
    Autorzy:
    Roggeveen LF; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
    Fleuren LM; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Guo T; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Thoral P; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    de Grooth HJ; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Swart EL; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Klausch TLT; Department of Epidemiology and Biostatistics, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    van der Voort PHJ; Intensive Care Unit, OLVG Oost, Oosterpark 9, 1091 AC, Amsterdam, The Netherlands.
    Girbes ARJ; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Bosman RJ; Intensive Care Unit, OLVG Oost, Oosterpark 9, 1091 AC, Amsterdam, The Netherlands.
    Elbers PWG; Department of Intensive Care Medicine, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
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    Źródło:
    Trials [Trials] 2019 Dec 18; Vol. 20 (1), pp. 745. Date of Electronic Publication: 2019 Dec 18.
    Typ publikacji:
    Clinical Trial Protocol; Journal Article
    MeSH Terms:
    Artificial Intelligence*
    Research Design*
    Anti-Bacterial Agents/*administration & dosage
    Drug Monitoring/*methods
    Shock, Septic/*drug therapy
    Adult ; Anti-Bacterial Agents/pharmacokinetics ; Big Data ; Dose-Response Relationship, Drug ; Equivalence Trials as Topic ; Female ; Humans ; Intensive Care Units ; Kaplan-Meier Estimate ; Male ; Multicenter Studies as Topic ; Netherlands/epidemiology ; Randomized Controlled Trials as Topic ; Severity of Illness Index ; Shock, Septic/diagnosis ; Shock, Septic/mortality ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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