Development and characterization of a DNA aptamer for MLL-AF9 expressing acute myeloid leukemia cells using whole cell-SELEX.
Autorzy:
Earnest KG; Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA. McConnell EM; Department of Chemistry, Carleton University, Ottawa, ON, Canada. Hassan EM; Department of Chemistry, Carleton University, Ottawa, ON, Canada. Wunderlich M; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Hosseinpour B; Department of Chemistry, Carleton University, Ottawa, ON, Canada. Bono BS; Department of Neuroscience, Carleton University, Ottawa, ON, Canada. Chee MJ; Department of Neuroscience, Carleton University, Ottawa, ON, Canada. Mulloy JC; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Willmore WG; Department of Chemistry, Carleton University, Ottawa, ON, Canada. DeRosaMC; Department of Chemistry, Carleton University, Ottawa, ON, Canada. maria.derosa@carleton.ca. Merino EJ; Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Sep 27; Vol. 11 (1), pp. 19174. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Development and Evaluation of a Quantitative Fluorescent Lateral Flow Immunoassay for Cystatin-C, a Renal Dysfunction Biomarker.
Autorzy:
Natarajan S; Healthcare Technology Innovation Centre, Indian Institute of Technology Madras, Chennai 600113, India. DeRosaMC; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada. Shah MI; Healthcare Technology Innovation Centre, Indian Institute of Technology Madras, Chennai 600113, India. Jayaraj J; Department of Electrical Engineering, Indian Institute of Technology, Madras, Chennai 600113, India.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 May 03; Vol. 21 (9). Date of Electronic Publication: 2021 May 03.
An In-Silico Pipeline for Rapid Screening of DNA Aptamers against Mycotoxins: The Case-Study of Fumonisin B1, Aflatoxin B1 and Ochratoxin A.
Autorzy:
Ciriaco F; Department of Chemistry, University of Bari, Via Orabona 4, 70126 Bari, Italy. De Leo V; Department of Chemistry, University of Bari, Via Orabona 4, 70126 Bari, Italy. Catucci L; Department of Chemistry, University of Bari, Via Orabona 4, 70126 Bari, Italy. Pascale M; Institute of Sciences of Food Production (ISPA), CNR-National Research Council of Italy, Via G. Amendola 122/O, 70126 Bari, Italy. Logrieco AF; Institute of Sciences of Food Production (ISPA), CNR-National Research Council of Italy, Via G. Amendola 122/O, 70126 Bari, Italy. DeRosaMC; Department of Chemistry, Carleton University, 1125 Colonel by Drive, Ottawa, ON K1S 5B6, Canada. De Girolamo A; Institute of Sciences of Food Production (ISPA), CNR-National Research Council of Italy, Via G. Amendola 122/O, 70126 Bari, Italy.
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Źródło:
Polymers [Polymers (Basel)] 2020 Dec 14; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 14.
DNA aptamers against bacterial cells can be efficiently selected by a SELEX process using state-of-the art qPCR and ultra-deep sequencing.
Autorzy:
Kolm C; Molecular Diagnostics Group, Department IFA-Tulln, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Tulln, Austria.; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria. Cervenka I; Molecular Diagnostics Group, Department IFA-Tulln, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Tulln, Austria.; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria. Aschl UJ; Molecular Diagnostics Group, Department IFA-Tulln, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Tulln, Austria.; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria. Baumann N; Molecular Diagnostics Group, Department IFA-Tulln, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Tulln, Austria.; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria. Jakwerth S; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria.; Institute for Hygiene and Applied Immunology, Medical University Vienna, Vienna, Austria. Krska R; Institute of Bioanalytics and Agro-Metabolomics, Department IFA-Tulln, University of Natural Resources and Life Sciences, Vienna (BOKU), Tulln, Austria.; School of Biological Sciences, Institute for Global Food Security, Queen's University Belfast, Belfast, Northern Ireland, UK. Mach RL; Research Group Synthetic Biology and Molecular Biotechnology (166-5-1), Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Vienna, Austria. Sommer R; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria.; Institute for Hygiene and Applied Immunology, Medical University Vienna, Vienna, Austria. DeRosaMC; Department of Chemistry, Carleton University, Ottawa, Canada. Kirschner AKT; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria.; Institute for Hygiene and Applied Immunology, Medical University Vienna, Vienna, Austria.; Research Unit Water Quality and Health, Department Physiology, Pharmacology and Microbiology, Karl Landsteiner University of Health Sciences, Krems, Austria. Farnleitner AH; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria.; Research Unit Water Quality and Health, Department Physiology, Pharmacology and Microbiology, Karl Landsteiner University of Health Sciences, Krems, Austria.; Research Group Environmental Microbiology and Molecular Diagnostics (166-5-3), Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Vienna, Austria. Reischer GH; Molecular Diagnostics Group, Department IFA-Tulln, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Tulln, Austria. .; ICC Interuniversity Cooperation Centre Water and Health, Vienna, Austria. .; Research Group Environmental Microbiology and Molecular Diagnostics (166-5-3), Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Vienna, Austria. .
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 01; Vol. 10 (1), pp. 20917. Date of Electronic Publication: 2020 Dec 01.
pH-Control in Aptamer-Based Diagnostics, Therapeutics, and Analytical Applications.
Autorzy:
Belleperche M; Department of Chemistry and Institute of Biochemistry, Carleton University, Ottawa, ON K1S5B6, Canada. . DeRosaMC; Department of Chemistry and Institute of Biochemistry, Carleton University, Ottawa, ON K1S5B6, Canada. .
Comparison of In-Solution Biorecognition Properties of Aptamers against Ochratoxin A.
Autorzy:
McKeague M; Chemistry Department, Carleton University, 1125 Colonel by Drive, Ottawa, ON K1S 5B6, Canada. . Velu R; Chemistry Department, Carleton University, 1125 Colonel by Drive, Ottawa, ON K1S 5B6, Canada. . De Girolamo A; Institute of Sciences of Food Production, National Research Council of Italy, via G. Amendola 122/O, Bari 70126, Italy. . Valenzano S; Institute of Sciences of Food Production, National Research Council of Italy, via G. Amendola 122/O, Bari 70126, Italy. . Pascale M; Institute of Sciences of Food Production, National Research Council of Italy, via G. Amendola 122/O, Bari 70126, Italy. . Smith M; Chemistry Department, Carleton University, 1125 Colonel by Drive, Ottawa, ON K1S 5B6, Canada. . DeRosaMC; Chemistry Department, Carleton University, 1125 Colonel by Drive, Ottawa, ON K1S 5B6, Canada. maria.derosa@carleton.ca.
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Źródło:
Toxins [Toxins (Basel)] 2016 Nov 15; Vol. 8 (11). Date of Electronic Publication: 2016 Nov 15.
Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection.
Autorzy:
Ruscito A; Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawa, ON K1S5B6, Canada. Smith M; Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawa, ON K1S5B6, Canada. Goudreau DN; Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawa, ON K1S5B6, Canada. DeRosaMC
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Źródło:
Journal of AOAC International [J AOAC Int] 2016 Jul; Vol. 99 (4), pp. 865-877. Date of Electronic Publication: 2016 Jun 16.
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