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Wyświetlanie 1-18 z 18
Tytuł:
Adjusting expected deaths for mortality displacement during the COVID-19 pandemic: a model based counterfactual approach at the level of individuals.
Autorzy:
Holleyman RJ; UK Health Security Agency, Wellington House; 133-155 Waterloo Road, London, SE1 8UG, UK. .; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, NE1 7RU, UK. .
Barnard S; School of Population Health, Curtin University, Bentley, WA, 6102, Australia.
Bauer-Staeb C; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Hughes A; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Dunn S; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Fox S; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Newton JN; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Fitzpatrick J; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Waller Z; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Deehan DJ; Newcastle Upon Tyne Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle Upon Tyne, NE7 7DN, UK.
Charlett A; UK Health Security Agency, Wellington House; 133-155 Waterloo Road, London, SE1 8UG, UK.
Gregson CL; Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1QU, UK.
Wilson R; Department of Public Health, Policy and Systems, University of Liverpool Waterhouse Building, Block B, Brownlow Street, Liverpool, L69 3GL, UK.
Fryers P; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
Goldblatt P; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.; Department of Epidemiology & Public Health, UCL Institute of Health Equity, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK.
Burton P; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, NE1 7RU, UK.; Office for Health Improvement and Disparities, Department of Health and Social Care, 39 Victoria Street, London, SW1H 0EU, UK.
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Źródło:
BMC medical research methodology [BMC Med Res Methodol] 2023 Oct 18; Vol. 23 (1), pp. 241. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/epidemiology
Frailty*
Hip Fractures*/epidemiology
Female ; Humans ; Male ; Pandemics ; Life Expectancy ; Mortality
Czasopismo naukowe
Tytuł:
Robotic- and orthosensor-assisted versus manual (ROAM) total knee replacement: a study protocol for a randomised controlled trial.
Autorzy:
Clement ND; Royal Infirmary of Edinburgh, Edinburgh, UK. .
Bardgett M; Newcastle University, Newcastle upon Tyne, UK.
Galloway S; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Baron YJ; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Smith K; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Weir DJ; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Deehan DJ; Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
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Źródło:
Trials [Trials] 2022 Jan 22; Vol. 23 (1), pp. 70. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Arthroplasty, Replacement, Knee*
Osteoarthritis, Knee*/surgery
Robotic Surgical Procedures*
Humans ; Knee Joint/diagnostic imaging ; Knee Joint/surgery ; Quality of Life ; Randomized Controlled Trials as Topic ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss.
Autorzy:
Dobson PF; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Dennis EP; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Hipps D; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Reeve A; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Laude A; Bioimaging Unit, Medical School, FMS Professional Services, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Bradshaw C; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Stamp C; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Smith A; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Deehan DJ; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Turnbull DM; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. .; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. .
Greaves LC; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. .; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 15; Vol. 10 (1), pp. 11643. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging/*genetics
Bone Resorption/*genetics
DNA Polymerase gamma/*genetics
DNA, Mitochondrial/*genetics
Mitochondria/*metabolism
Osteogenesis/*genetics
Osteoporosis/*genetics
Animals ; Bone Density/physiology ; Bone Resorption/metabolism ; Bone Resorption/physiopathology ; Calcification, Physiologic ; Cell Count ; DNA Polymerase gamma/deficiency ; DNA, Mitochondrial/metabolism ; Electron Transport Complex I/deficiency ; Electron Transport Complex I/genetics ; Electron Transport Complex IV/genetics ; Electron Transport Complex IV/metabolism ; Female ; Femur/metabolism ; Femur/pathology ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/pathology ; Mutation ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Osteoclasts/metabolism ; Osteoclasts/pathology ; Osteoporosis/metabolism ; Osteoporosis/physiopathology ; Physical Conditioning, Animal
Czasopismo naukowe
Tytuł:
Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief.
Autorzy:
Clement ND; Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, UK. .
Weir D; Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
Holland J; Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
Deehan DJ; Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
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Źródło:
Knee surgery & related research [Knee Surg Relat Res] 2020 Jun 17; Vol. 32 (1), pp. 32. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Reduced telomere length is associated with fibrotic joint disease suggesting that impaired telomere repair contributes to joint fibrosis.
Autorzy:
Kalson NS; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.; Department of Orthopaedics, Newcastle University Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Brock TM; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.; Department of Orthopaedics, Newcastle University Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Mangino M; Department of Twin Research & Genetic Epidemiology, King's College London, London, United Kingdom.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, United Kingdom.
Fabiane SM; Department of Twin Research & Genetic Epidemiology, King's College London, London, United Kingdom.
Mann DA; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.
Borthwick LA; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.
Deehan DJ; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.; Department of Orthopaedics, Newcastle University Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Williams FMK; Department of Twin Research & Genetic Epidemiology, King's College London, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2018 Jan 02; Vol. 13 (1), pp. e0190120. Date of Electronic Publication: 2018 Jan 02 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Telomere Shortening*
Joint Diseases/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Fibrosis ; Humans ; Joint Diseases/pathology ; Male ; Middle Aged ; United Kingdom ; Young Adult
Czasopismo naukowe
Tytuł:
Unique quadruple immunofluorescence assay demonstrates mitochondrial respiratory chain dysfunction in osteoblasts of aged and PolgA(-/-) mice.
Autorzy:
Dobson PF; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
Rocha MC; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
Grady JP; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
Chrysostomou A; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
Hipps D; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
Watson S; Musculoskeletal Research Group, Medical School, Newcastle University, United Kingdom.
Greaves LC; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.; MRC/BBSRC Centre for Ageing and Vitality, Newcastle University, United Kingdom.
Deehan DJ; Institute of Cellular Medicine, Newcastle University, United Kingdom.
Turnbull DM; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.; MRC/BBSRC Centre for Ageing and Vitality, Newcastle University, United Kingdom.
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Źródło:
Scientific reports [Sci Rep] 2016 Aug 24; Vol. 6, pp. 31907. Date of Electronic Publication: 2016 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging/*genetics
DNA Polymerase gamma/*genetics
Electron Transport Chain Complex Proteins/*metabolism
Osteoblasts/*metabolism
Osteoporosis/*genetics
Aging/metabolism ; Animals ; Disease Models, Animal ; Fluorescent Antibody Technique ; Humans ; Mice ; Mice, Transgenic ; Mitochondrial Proteins/metabolism ; Mutation ; Osteoblasts/pathology ; Osteoporosis/metabolism
Czasopismo naukowe
Tytuł:
Implant Optimisation for Primary Hip Replacement in Patients over 60 Years with Osteoarthritis: A Cohort Study of Clinical Outcomes and Implant Costs Using Data from England and Wales.
Autorzy:
Jameson SS; School of Medicine, Pharmacy and Health, Durham University, Queen's Campus, University Boulevard, Stockton-on-Tees, TS17 6BH, United Kingdom.; The National Joint Registry for England and Wales, London, United Kingdom.; Department of Orthopaedic Surgery, South Tees Hospitals NHS Foundation Trust, Marton Road, Middlesbrough, TS4 3BW, United Kingdom.
Mason J; School of Medicine, Pharmacy and Health, Durham University, Queen's Campus, University Boulevard, Stockton-on-Tees, TS17 6BH, United Kingdom.
Baker PN; The National Joint Registry for England and Wales, London, United Kingdom.; Department of Orthopaedic Surgery, South Tees Hospitals NHS Foundation Trust, Marton Road, Middlesbrough, TS4 3BW, United Kingdom.
Gregg PJ; The National Joint Registry for England and Wales, London, United Kingdom.; Department of Orthopaedic Surgery, South Tees Hospitals NHS Foundation Trust, Marton Road, Middlesbrough, TS4 3BW, United Kingdom.
Deehan DJ; Department of Orthopaedic Surgery, Newcastle Hospitals NHS Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, United Kingdom.
Reed MR; Department of Orthopaedic Surgery, Northumbria Healthcare NHS Foundation Trust, Woodhorn Lane, Ashington, Northumberland, NE63 9JJ, United Kingdom.
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Źródło:
PloS one [PLoS One] 2015 Nov 12; Vol. 10 (11), pp. e0140309. Date of Electronic Publication: 2015 Nov 12 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthroplasty, Replacement, Hip/*statistics & numerical data
Hip Prosthesis/*statistics & numerical data
Osteoarthritis, Hip/*surgery
Registries/*statistics & numerical data
Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip/methods ; Bone Cements/chemistry ; Cost-Benefit Analysis ; England ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Outcome Assessment, Health Care/economics ; Outcome Assessment, Health Care/methods ; Outcome Assessment, Health Care/statistics & numerical data ; Polyethylene ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Surveys and Questionnaires ; Wales
Czasopismo naukowe
Tytuł:
A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty.
Autorzy:
Dixon D; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Coates J; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
del Carpio Pons A; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Horabin J; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Walker A; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Abdul N; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne NE7 7DN, UK.
Kalson NS; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne NE7 7DN, UK.
Brewster NT; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne NE7 7DN, UK.
Weir DJ; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne NE7 7DN, UK.
Deehan DJ; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne NE7 7DN, UK.
Mann DA; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Borthwick LA; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
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Źródło:
Scientific reports [Sci Rep] 2015 Nov 10; Vol. 5, pp. 16466. Date of Electronic Publication: 2015 Nov 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin 1 Receptor Antagonist Protein/*metabolism
Joint Diseases/*metabolism
Joint Diseases/*pathology
Knee Joint/*metabolism
Knee Joint/*pathology
Arthroplasty, Replacement, Knee/adverse effects ; Biomarkers ; Cytokines/metabolism ; Female ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibrosis ; Gene Expression ; Humans ; Inflammation Mediators/metabolism ; Interleukin 1 Receptor Antagonist Protein/genetics ; Joint Diseases/etiology ; Joint Diseases/surgery ; Knee Joint/surgery ; Male ; Phenotype ; Postoperative Period ; Synovial Membrane/cytology ; Transforming Growth Factor beta1/pharmacology
Czasopismo naukowe
Tytuł:
Fibrosis is a common outcome following total knee arthroplasty.
Autorzy:
Abdul N; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Dixon D; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Walker A; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Horabin J; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Smith N; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Weir DJ; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
Brewster NT; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
Deehan DJ; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Musculoskeletal Unit, Freeman Hospital, Newcastle Hospitals, NHS Trust, High Heaton, Newcastle upon Tyne, NE7 7DN, UK.
Mann DA; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Borthwick LA; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
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Źródło:
Scientific reports [Sci Rep] 2015 Nov 10; Vol. 5, pp. 16469. Date of Electronic Publication: 2015 Nov 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Joint Diseases/*etiology
Joint Diseases/*pathology
Knee Joint/*pathology
Actins/genetics ; Actins/metabolism ; Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Knee/adverse effects ; Arthroscopes ; Biopsy ; Collagen/metabolism ; Female ; Fibrosis ; Gene Expression ; Humans ; Hydroxyproline/metabolism ; Immunohistochemistry ; Joint Diseases/diagnosis ; Joint Diseases/surgery ; Knee Joint/surgery ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Prognosis ; Synovial Membrane/metabolism ; Synovial Membrane/pathology
Czasopismo naukowe
Tytuł:
Joint Stiffness Is Heritable and Associated with Fibrotic Conditions and Joint Replacement.
Autorzy:
Williams FM; Department of Twin Research & Genetic Epidemiology, King's College London, London United Kingdom.
Kalson NS; Department of Orthopaedics, The Royal Victoria Infirmary and the Freeman Hospital, Newcastle upon Tyne, United Kingdom; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcasltle upon Tyne, United Kingdom.
Fabiane SM; Department of Twin Research & Genetic Epidemiology, King's College London, London United Kingdom.
Mann DA; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcasltle upon Tyne, United Kingdom.
Deehan DJ; Department of Orthopaedics, The Royal Victoria Infirmary and the Freeman Hospital, Newcastle upon Tyne, United Kingdom; Fibrosis Research Group, Institute of Cellular Medicine, University of Newcastle, Newcasltle upon Tyne, United Kingdom.
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Źródło:
PloS one [PLoS One] 2015 Jul 21; Vol. 10 (7), pp. e0133629. Date of Electronic Publication: 2015 Jul 21 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Twin Study
MeSH Terms:
Range of Motion, Articular*
Dupuytren Contracture/*physiopathology
Fibrosis/*physiopathology
Adult ; Aged ; Arthroplasty, Replacement, Hip ; Arthroplasty, Replacement, Knee ; Body Mass Index ; Female ; Genetic Predisposition to Disease ; Hip Joint/physiopathology ; Humans ; Knee Joint/physiopathology ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Osteoarthritis, Hip/surgery ; Osteoarthritis, Knee/surgery ; Risk Factors ; Surveys and Questionnaires ; United Kingdom ; Young Adult
Czasopismo naukowe
Tytuł:
Have cementless and resurfacing components improved the medium-term results of hip replacement for patients under 60 years of age?
Autorzy:
Jameson SS; School of Medicine, Pharmacy and Health , Durham University, Queen's Campus, University Boulevard, Stockton-on-Tees , UK .
Mason J
Baker P
Gregg PJ
Porter M
Deehan DJ
Reed MR
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Źródło:
Acta orthopaedica [Acta Orthop] 2015 Feb; Vol. 86 (1), pp. 7-17. Date of Electronic Publication: 2014 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hip Prosthesis*
Registries*
Arthroplasty, Replacement, Hip/*methods
Cementation/*methods
Osteoarthritis, Hip/*surgery
Adolescent ; Adult ; Cohort Studies ; England ; Female ; Humans ; Male ; Middle Aged ; Patient Outcome Assessment ; Proportional Hazards Models ; Reoperation/statistics & numerical data ; Sex Factors ; Treatment Outcome ; Wales ; Young Adult
Czasopismo naukowe
Tytuł:
No functional benefit of larger femoral heads and alternative bearings at 6 months following primary hip replacement.
Autorzy:
Jameson SS; The National Joint Registry for England and Wales.
Mason JM
Baker PN
Gregg PJ
Deehan DJ
Reed MR
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Źródło:
Acta orthopaedica [Acta Orthop] 2015 Feb; Vol. 86 (1), pp. 32-40. Date of Electronic Publication: 2014 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hip Prosthesis*
Prosthesis Design*
Registries*
Arthroplasty, Replacement, Hip/*methods
Osteoarthritis, Hip/*surgery
Adult ; Aged ; Aged, 80 and over ; Ceramics ; Cohort Studies ; England ; Female ; Humans ; Male ; Metals ; Middle Aged ; Patient Outcome Assessment ; Polyethylene ; Treatment Outcome ; Wales
Czasopismo naukowe
Tytuł:
Investigating the biological response of human mesenchymal stem cells to titanium surfaces.
Autorzy:
German MJ; Centre for Oral Health Research, School of Dental Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4BW, UK. .
Osei-Bempong C; Institute of Genetic Medicine, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, NE1 4EP, UK. .
Knuth CA; North East England Stem Cell Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, NE1 4EP, UK. .
Deehan DJ; Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne NHS Hospitals Foundation Trust, Freeman Road, High Heaton, Newcastle upon Tyne, NE7 7DN, UK. david.deehan@nuth.nhs.uk.
Oldershaw RA; North East England Stem Cell Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, NE1 4EP, UK. .; Department of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, Faculty of Health and Life Sciences, The University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2014 Dec 12; Vol. 9, pp. 135. Date of Electronic Publication: 2014 Dec 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone-Implant Interface/*physiology
Mesenchymal Stem Cells/*physiology
Titanium/*metabolism
Adult ; Bone Screws ; Cells, Cultured ; Female ; Humans ; Male ; Microscopy, Electron, Scanning ; Middle Aged ; Osteogenesis/physiology
Czasopismo naukowe
Tytuł:
Quality of life after knee revision arthroplasty.
Autorzy:
Deehan DJ; Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK. david.deehan@nuth.nhs.uk
Murray JD
Birdsall PD
Pinder IM
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Źródło:
Acta orthopaedica [Acta Orthop] 2006 Oct; Vol. 77 (5), pp. 761-6.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Quality of Life*
Arthroplasty, Replacement, Knee/*psychology
Adult ; Arthroplasty, Replacement, Knee/adverse effects ; Female ; Follow-Up Studies ; Humans ; Male ; Prospective Studies ; Prosthesis Failure ; Reoperation
Czasopismo naukowe
Tytuł:
Endoscopic anterior cruciate ligament reconstruction using a four strand hamstring tendon construct.
Autorzy:
Deehan DJ; Freeman Hospital, Newcastle upon Tyne, UK. />Pinczewski LA
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Źródło:
Journal of the Royal College of Surgeons of Edinburgh [J R Coll Surg Edinb] 2002 Feb; Vol. 47 (1), pp. 428-36.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anterior Cruciate Ligament Injuries*
Endoscopy*
Plastic Surgery Procedures*
Anterior Cruciate Ligament/*surgery
Tendons/*transplantation
Thigh/*surgery
Humans
Czasopismo naukowe
Tytuł:
Postphlebitic syndrome after total knee arthroplasty: 405 patients examined 2-10 years after surgery.
Autorzy:
Deehan DJ; Department of Orthopaedics, Freeman Hospital, Newcastle-upon-Tyne, UK. />Siddique M
Weir DJ
Pinder IM
Lingard EM
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Źródło:
Acta orthopaedica Scandinavica [Acta Orthop Scand] 2001 Feb; Vol. 72 (1), pp. 42-5.
Typ publikacji:
Journal Article
MeSH Terms:
Arthroplasty, Replacement, Knee/*adverse effects
Postphlebitic Syndrome/*etiology
Adult ; Aged ; Aged, 80 and over ; Bone Cements ; Cross-Sectional Studies ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Physical Examination ; Postphlebitic Syndrome/classification ; Postphlebitic Syndrome/diagnosis ; Prevalence ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Severity of Illness Index ; Surveys and Questionnaires ; Time Factors
Czasopismo naukowe
Tytuł:
Serum albumin: a prognostic indicator in patients with colorectal cancer.
Autorzy:
Heys SD; Surgical Nutrition and Metabolism Unit, University of Aberdeen, UK.
Walker LG
Deehan DJ
Eremin OE
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Źródło:
Journal of the Royal College of Surgeons of Edinburgh [J R Coll Surg Edinb] 1998 Jun; Vol. 43 (3), pp. 163-8.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Biomarkers, Tumor/*analysis
Colorectal Neoplasms/*blood
Colorectal Neoplasms/*diagnosis
Serum Albumin/*analysis
Adult ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/mortality ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Proportional Hazards Models ; Sensitivity and Specificity ; Survival Rate
Czasopismo naukowe
Tytuł:
Correlation of serum cytokine and acute phase reactant levels with alterations in weight and serum albumin in patients receiving immunotherapy with recombinant IL-2.
Autorzy:
Deehan DJ; Department of Surgery, University of Aberdeen, UK.
Heys SD
Simpson W
Herriot R
Broom J
Eremin O
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 1994 Mar; Vol. 95 (3), pp. 366-72.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma/*drug therapy
Colorectal Neoplasms/*drug therapy
Interleukin-2/*therapeutic use
Acute-Phase Proteins/analysis ; Body Weight ; C-Reactive Protein/analysis ; Complement System Proteins/analysis ; Cytokines/blood ; Humans ; Immunotherapy ; Infusions, Intravenous ; Interleukin-2/adverse effects ; Interleukin-6/blood ; Predictive Value of Tests ; Recombinant Proteins/adverse effects ; Recombinant Proteins/therapeutic use ; Serum Albumin/analysis ; Tumor Necrosis Factor-alpha/analysis
Czasopismo naukowe
    Wyświetlanie 1-18 z 18

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