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Wyszukujesz frazę ""Defective Viruses"" wg kryterium: Temat


Tytuł :
Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture.
Autorzy :
Rüdiger D; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Pelz L; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Hein MD; Chair of Bioprocess Engineering, Institute of Process Engineering, Faculty of Process & Systems Engineering, Otto-von-Guericke University, Magdeburg, Germany.
Kupke SY; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Reichl U; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.; Chair of Bioprocess Engineering, Institute of Process Engineering, Faculty of Process & Systems Engineering, Otto-von-Guericke University, Magdeburg, Germany.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 Sep 07; Vol. 17 (9), pp. e1009357. Date of Electronic Publication: 2021 Sep 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Defective Viruses*/chemistry
Defective Viruses*/genetics
Defective Viruses*/pathogenicity
Influenza A virus*/chemistry
Influenza A virus*/genetics
Influenza A virus*/pathogenicity
Models, Biological*
Orthomyxoviridae Infections/*virology
Virus Replication/*physiology
Animals ; Antiviral Agents ; Cell Culture Techniques ; Dogs ; Madin Darby Canine Kidney Cells ; RNA, Viral/genetics
Czasopismo naukowe
Tytuł :
Dengue virus-free defective interfering particles have potent and broad anti-dengue virus activity.
Autorzy :
Li D; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Lin MH; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Rawle DJ; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Jin H; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Wu Z; Ningxia Center for Disease Control and Prevention, Ningxia, China.
Wang L; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Lor M; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Hussain M; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Aaskov J; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Harrich D; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia. .
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Źródło :
Communications biology [Commun Biol] 2021 May 11; Vol. 4 (1), pp. 557. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Defective Viruses*/genetics
Defective Viruses*/metabolism
Virus Replication*
Dengue/*prevention & control
Dengue Vaccines/*therapeutic use
Dengue Virus/*growth & development
Animals ; Cell Line, Tumor ; Chlorocebus aethiops ; Dengue/virology ; Dengue Virus/genetics ; Dengue Virus/metabolism ; Genes, Reporter ; HEK293 Cells ; Host-Pathogen Interactions ; Humans ; Luminescent Proteins/biosynthesis ; Luminescent Proteins/genetics ; RNA, Viral/biosynthesis ; RNA, Viral/genetics ; Vero Cells ; Viral Load
Czasopismo naukowe
Tytuł :
Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes.
Autorzy :
Felt SA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine, St Louis, MO, USA.
Sun Y; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology and Immunology, University of Rochester, Rochester, NY, USA.
Jozwik A; Department of Infectious Disease, Imperial College London, London, UK.
Paras A; Department of Infectious Disease, Imperial College London, London, UK.
Habibi MS; Department of Infectious Disease, Imperial College London, London, UK.
Nickle D; Merck & Co., Inc., Kenilworth, NJ, USA.
Anderson L; Pediatric Infectious Disease, Emory University, Atlanta, GA, USA.
Achouri E; Department of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine, St Louis, MO, USA.
Feemster KA; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Cárdenas AM; Infectious Disease Diagnostics Laboratory, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Becton, Dickinson and Company, Sparks, MD, USA.
Turi KN; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Chang M; Merck & Co., Inc., Kenilworth, NJ, USA.
Hartert TV; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Sengupta S; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Chiu C; Department of Infectious Disease, Imperial College London, London, UK. .
López CB; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. .; Department of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine, St Louis, MO, USA. .
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Źródło :
Nature microbiology [Nat Microbiol] 2021 May; Vol. 6 (5), pp. 672-681. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome, Viral*
Defective Viruses/*genetics
Nasal Mucosa/*virology
Respiratory Syncytial Virus Infections/*virology
Respiratory Syncytial Virus, Human/*genetics
Cohort Studies ; Defective Viruses/physiology ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Nasal Mucosa/metabolism ; Respiratory Syncytial Virus Infections/metabolism ; Respiratory Syncytial Virus, Human/physiology
Czasopismo naukowe
Tytuł :
Influenza virus DI particles: Defective interfering or delightfully interesting?
Autorzy :
Alnaji FG; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
Brooke CB; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 May 21; Vol. 16 (5), pp. e1008436. Date of Electronic Publication: 2020 May 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Defective Viruses/*genetics
Defective Viruses/*metabolism
Orthomyxoviridae/*metabolism
Animals ; Defective Viruses/physiology ; Humans ; Influenza, Human/genetics ; Orthomyxoviridae/genetics ; Orthomyxoviridae Infections/genetics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Virion/genetics ; Virion/metabolism ; Virus Replication/genetics
Czasopismo naukowe
Tytuł :
A real-time and high-throughput neutralization test based on SARS-CoV-2 pseudovirus containing monomeric infrared fluorescent protein as reporter.
Autorzy :
Tsai WY; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Ching LL; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Hsieh SC; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Melish ME; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Kapi'olani Medical Center for Women and Children, Honolulu, HI, USA.; Department of Pediatrics, John A. Burns School of Medicine, Honolulu, HI, USA.
Nerurkar VR; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Wang WK; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 894-904.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Viral/*blood
COVID-19/*immunology
Neutralization Tests/*methods
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Ammonium Chloride/pharmacology ; Animals ; Antigen-Antibody Reactions ; Blotting, Western ; COVID-19/blood ; Chlorocebus aethiops ; Convalescence ; Defective Viruses/genetics ; Genes, Reporter ; Genetic Vectors/immunology ; HEK293 Cells ; HIV-1/genetics ; Humans ; Immunoglobulin G/immunology ; Lentivirus/genetics ; Mutagenesis, Site-Directed ; Pandemics ; Point Mutation ; Spike Glycoprotein, Coronavirus/genetics ; Vero Cells
Czasopismo naukowe
Tytuł :
Targeting Conserved Sequences Circumvents the Evolution of Resistance in a Viral Gene Drive against Human Cytomegalovirus.
Autorzy :
Walter M; Buck Institute for Research on Aging, Novato, California, USA.
Perrone R; Buck Institute for Research on Aging, Novato, California, USA.
Verdin E; Buck Institute for Research on Aging, Novato, California, USA.
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Źródło :
Journal of virology [J Virol] 2021 Jul 12; Vol. 95 (15), pp. e0080221. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CRISPR-Cas Systems/*genetics
Conserved Sequence/*genetics
Cytomegalovirus/*genetics
Gene Drive Technology/*methods
Viral Interference/*genetics
Amino Acid Sequence ; Base Sequence ; Cell Line ; Cytomegalovirus/growth & development ; Cytomegalovirus Infections/prevention & control ; Cytomegalovirus Infections/therapy ; Defective Viruses/genetics ; Drug Resistance, Viral/genetics ; Genes, Viral/genetics ; Humans ; Sequence Alignment ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro through Stimulation of Innate Immunity.
Autorzy :
Rand U; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Kupke SY; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, 39106 Magdeburg, Germany.
Shkarlet H; Immune Regulation Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.; Institute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany.
Hein MD; Bioprocess Engineering, Otto von Guericke University Magdeburg, 39106 Magdeburg, Germany.
Hirsch T; Immune Regulation Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Marichal-Gallardo P; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, 39106 Magdeburg, Germany.
Cicin-Sain L; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.; German Centre for Infection Research, Hannover-Braunschweig Site, 38124 Braunschweig, Germany.; Centre for Individualized Infection Medicine, a Joint Venture of Helmholtz Centre for Infection Research and Medical School Hannover, 38124 Braunschweig, Germany.
Reichl U; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, 39106 Magdeburg, Germany.; Bioprocess Engineering, Otto von Guericke University Magdeburg, 39106 Magdeburg, Germany.
Bruder D; Immune Regulation Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.; Institute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany.
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Źródło :
Cells [Cells] 2021 Jul 11; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
COVID-19/*drug therapy
Immunity, Innate/*drug effects
SARS-CoV-2/*drug effects
Animals ; Antiviral Agents/immunology ; COVID-19/immunology ; Cell Line, Tumor ; Chlorocebus aethiops ; Defective Viruses/immunology ; Humans ; Influenza A virus/immunology ; SARS-CoV-2/immunology ; SARS-CoV-2/physiology ; Vero Cells ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection.
Autorzy :
Wang C; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA.
Forst CV; Mount Sinai Center for Transformative Disease Modeling, Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Chou TW; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA.
Geber A; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA.
Wang M; Mount Sinai Center for Transformative Disease Modeling, Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Hamou W; Mount Sinai Center for Transformative Disease Modeling, Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Smith M; Mount Sinai Center for Transformative Disease Modeling, Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Sebra R; Mount Sinai Center for Transformative Disease Modeling, Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Zhang B; Mount Sinai Center for Transformative Disease Modeling, Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Zhou B; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA.
Ghedin E; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA .; College of Global Public Health, New York University, New York, New York, USA.
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Źródło :
MBio [mBio] 2020 Jan 14; Vol. 11 (1). Date of Electronic Publication: 2020 Jan 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Defective Viruses/*genetics
Epithelial Cells/*virology
Host Microbial Interactions/*immunology
A549 Cells ; Bronchi/cytology ; Bronchi/virology ; Cells, Cultured ; Defective Viruses/immunology ; Genome, Viral ; Humans ; Influenza A virus/physiology ; RNA, Viral/genetics ; Sequence Analysis, RNA ; Single-Cell Analysis ; Virus Replication
Czasopismo naukowe
Tytuł :
High-brightness anterograde transneuronal HSV1 H129 tracer modified using a Trojan horse-like strategy.
Autorzy :
Su P; Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, 430074, China.; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.
Ying M; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Han Z; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Xia J; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.
Jin S; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.; Huazhong University of Science and Technology (HUST)-Suzhou Institute for Brainsmatics, JITRI Institute for Brainsmatics, Suzhou, 215125, China.
Li Y; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.
Wang H; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China. .; University of Chinese Academy of Sciences, Beijing, 100049, China. .; Shenzhen Key Lab of Neuropsychiatric Modulation, Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China. .
Xu F; Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, 430074, China. .; Center for Brain Science, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China. .; University of Chinese Academy of Sciences, Beijing, 100049, China. .; Shenzhen Key Lab of Neuropsychiatric Modulation, Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China. .; Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China. .
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Źródło :
Molecular brain [Mol Brain] 2020 Jan 13; Vol. 13 (1), pp. 5. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Axonal Transport/*physiology
Brain/*cytology
Defective Viruses/*physiology
Dependovirus/*physiology
Green Fluorescent Proteins/*analysis
Helper Viruses/*physiology
Herpesvirus 1, Human/*physiology
Neural Pathways/*ultrastructure
Neuroanatomical Tract-Tracing Techniques/*methods
Neuronal Tract-Tracers/*analysis
Neurons/*ultrastructure
Reassortant Viruses/*physiology
Animals ; Cell Line ; Cell Nucleus/virology ; Defective Viruses/genetics ; Dependovirus/genetics ; Genes, Reporter ; Genes, Synthetic ; Green Fluorescent Proteins/biosynthesis ; Green Fluorescent Proteins/genetics ; Helper Viruses/genetics ; Herpesvirus 1, Human/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/virology ; Reassortant Viruses/genetics ; Viral Replicase Complex Proteins/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts.
Autorzy :
Rezelj VV; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Carrau L; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Merwaiss F; Institut Pasteur, Viruses and RNA Interference Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Levi LI; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.; École doctorale BioSPC, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Erazo D; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Tran QD; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.; École doctorale BioSPC, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Henrion-Lacritick A; Institut Pasteur, Viruses and RNA Interference Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Gausson V; Institut Pasteur, Viruses and RNA Interference Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Suzuki Y; Institut Pasteur, Viruses and RNA Interference Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Shengjuler D; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Meyer B; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Vallet T; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Weger-Lucarelli J; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Bernhauerová V; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Titievsky A; Tauber Bioinformatics Research Center, University of Haifa, Haifa, Israel.
Sharov V; Tauber Bioinformatics Research Center, University of Haifa, Haifa, Israel.
Pietropaoli S; Institut Pasteur, Unité de Virologie Structurale, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Diaz-Salinas MA; Institut Pasteur, Unité de Recherche et d'Expertise Environnement et Risques Infectieux, Groupe Arbovirus, Paris, Cedex 15, France.
Legros V; Institut Pasteur, Unité de Virologie Structurale, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Pardigon N; Institut Pasteur, Unité de Recherche et d'Expertise Environnement et Risques Infectieux, Groupe Arbovirus, Paris, Cedex 15, France.
Barba-Spaeth G; Institut Pasteur, Unité de Virologie Structurale, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
Brodsky L; Tauber Bioinformatics Research Center, University of Haifa, Haifa, Israel.
Saleh MC; Institut Pasteur, Viruses and RNA Interference Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France. .
Vignuzzi M; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France. .
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Źródło :
Nature communications [Nat Commun] 2021 Apr 16; Vol. 12 (1), pp. 2290. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antiviral Agents/*administration & dosage
Defective Viruses/*genetics
Mosquito Vectors/*drug effects
Zika Virus/*genetics
Zika Virus Infection/*drug therapy
Aedes/drug effects ; Aedes/virology ; Animals ; Chlorocebus aethiops ; Computational Biology ; Directed Molecular Evolution ; Disease Models, Animal ; Female ; Genetic Fitness ; Genome, Viral/genetics ; HEK293 Cells ; Humans ; Mice ; Mosquito Control/methods ; Mosquito Vectors/virology ; Open Reading Frames/genetics ; RNA, Viral/genetics ; Vero Cells ; Zika Virus Infection/transmission ; Zika Virus Infection/virology
Czasopismo naukowe
Tytuł :
Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes.
Autorzy :
Levi LI; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.; École doctorale BioSPC, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Rezelj VV; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.
Henrion-Lacritick A; Institut Pasteur, Viruses and RNAi Unit, CNRS UMR 3569, Paris, France.
Erazo D; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.
Boussier J; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.; École doctorale Frontières du vivant, Université Paris Diderot, Paris, France.
Vallet T; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.
Bernhauerová V; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.; Department of Biophysics and Physical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic.
Suzuki Y; Institut Pasteur, Viruses and RNAi Unit, CNRS UMR 3569, Paris, France.
Carrau L; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.; École doctorale BioSPC, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Weger-Lucarelli J; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.; Department of Biomedical Sciences and Pathobiology, Virginia Tech, VA-MD Regional College of Veterinary Medicine, Blacksburg, Virginia, United States of America.
Saleh MC; Institut Pasteur, Viruses and RNAi Unit, CNRS UMR 3569, Paris, France.
Vignuzzi M; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Feb 08; Vol. 17 (2), pp. e1009110. Date of Electronic Publication: 2021 Feb 08 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genome, Viral*
Virus Replication*
Aedes/*virology
Antiviral Agents/*pharmacology
Chikungunya Fever/*transmission
Chikungunya virus/*genetics
Defective Viruses/*genetics
Animals ; Chikungunya Fever/immunology ; Chikungunya Fever/virology ; Chikungunya virus/growth & development ; Chikungunya virus/isolation & purification ; Humans ; Mosquito Vectors/virology
Czasopismo naukowe
Tytuł :
The Impact of Defective Viruses on Infection and Immunity.
Autorzy :
Genoyer E; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; email: .
López CB; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; email: .
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Źródło :
Annual review of virology [Annu Rev Virol] 2019 Sep 29; Vol. 6 (1), pp. 547-566. Date of Electronic Publication: 2019 May 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Genome, Viral*
Defective Viruses/*genetics
RNA Viruses/*genetics
Virus Diseases/*immunology
Animals ; Defective Viruses/physiology ; Humans ; Immunity, Innate ; RNA Viruses/physiology ; Virus Diseases/virology ; Virus Replication
Czasopismo naukowe
Tytuł :
Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread.
Autorzy :
Jacobs NT; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Onuoha NO; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Antia A; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Steel J; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Antia R; Department of Biology, Emory University, Atlanta, GA, USA.
Lowen AC; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. .; Emory-UGA Center of Excellence for Influenza Research and Surveillance, Emory University School of Medicine, Atlanta, GA, USA. .
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Źródło :
Nature communications [Nat Commun] 2019 Aug 06; Vol. 10 (1), pp. 3526. Date of Electronic Publication: 2019 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genome, Viral*
Defective Viruses/*pathogenicity
Influenza A Virus, H3N2 Subtype/*pathogenicity
Influenza, Human/*transmission
Virus Replication/*genetics
Animals ; Defective Viruses/genetics ; Disease Models, Animal ; Dogs ; Evolution, Molecular ; Female ; Guinea Pigs ; HEK293 Cells ; Humans ; Influenza A Virus, H3N2 Subtype/genetics ; Influenza, Human/virology ; Likelihood Functions ; Madin Darby Canine Kidney Cells ; Models, Biological ; RNA, Viral/genetics ; Single-Cell Analysis ; Viral Load ; Virion/genetics ; Virus Shedding/genetics
Czasopismo naukowe
Tytuł :
Defective viral genomes are key drivers of the virus-host interaction.
Autorzy :
Vignuzzi M; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
López CB; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. .
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Źródło :
Nature microbiology [Nat Microbiol] 2019 Jul; Vol. 4 (7), pp. 1075-1087. Date of Electronic Publication: 2019 Jun 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Host-Pathogen Interactions*
Defective Viruses/*genetics
Genome, Viral/*physiology
Adjuvants, Immunologic ; Animals ; Antiviral Agents ; Biological Evolution ; Defective Viruses/classification ; Defective Viruses/growth & development ; Defective Viruses/pathogenicity ; Genome, Viral/genetics ; Humans ; RNA Viruses/classification ; RNA Viruses/genetics ; RNA Viruses/growth & development ; RNA Viruses/pathogenicity ; Virus Replication
Czasopismo naukowe
Tytuł :
Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm.
Autorzy :
Bosma TJ; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Karagiannis K; Department of Biochemistry and Molecular Medicine, George Washington University Medical Center, Washington, DC, United States of America.; Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Santana-Quintero L; Office of Hematology and Oncology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Ilyushina N; Division of Biotechnology Review and Research II, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Zagorodnyaya T; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Petrovskaya S; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Laassri M; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Donnelly RP; Division of Biotechnology Review and Research II, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Rubin S; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Simonyan V; Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Sauder CJ; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
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Źródło :
PloS one [PLoS One] 2019 May 17; Vol. 14 (5), pp. e0216944. Date of Electronic Publication: 2019 May 17 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Genome, Viral*
Chromosome Mapping/*statistics & numerical data
Defective Viruses/*genetics
Mumps virus/*genetics
Parainfluenza Virus 5/*genetics
Sendai virus/*genetics
Animals ; Chromosome Mapping/methods ; DNA Primers/chemical synthesis ; DNA Primers/metabolism ; Datasets as Topic ; Defective Viruses/classification ; High-Throughput Nucleotide Sequencing/statistics & numerical data ; Humans ; Molecular Typing ; Mumps virus/classification ; Parainfluenza Virus 5/classification ; Real-Time Polymerase Chain Reaction ; Sendai virus/classification ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Generation of a purely clonal defective interfering influenza virus.
Autorzy :
Yamagata Y; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.; Laboratory of Ultrastructural Virology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, Japan.
Muramoto Y; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.
Miyamoto S; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.; Department of Molecular Virology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shindo K; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.
Nakano M; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.; Laboratory of Ultrastructural Virology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, Japan.
Noda T; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.; Laboratory of Ultrastructural Virology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, Japan.
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Źródło :
Microbiology and immunology [Microbiol Immunol] 2019 May; Vol. 63 (5), pp. 164-171. Date of Electronic Publication: 2019 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Defective Viruses/*genetics
Influenza A virus/*genetics
RNA, Viral/*genetics
RNA-Dependent RNA Polymerase/*genetics
Viral Proteins/*genetics
Virus Replication/*genetics
Animals ; Antiviral Agents/therapeutic use ; Defective Viruses/physiology ; Dogs ; HEK293 Cells ; Humans ; Influenza, Human/drug therapy ; Madin Darby Canine Kidney Cells ; Orthomyxoviridae Infections/drug therapy
Czasopismo naukowe
Tytuł :
A system for production of defective interfering particles in the absence of infectious influenza A virus.
Autorzy :
Bdeir N; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany.
Arora P; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany.
Gärtner S; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.
Hoffmann M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.
Reichl U; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.; Otto von Guericke University Magdeburg, Chair for Bioprocess Engineering, Magdeburg, Germany.
Pöhlmann S; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany.
Winkler M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.
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Źródło :
PloS one [PLoS One] 2019 Mar 01; Vol. 14 (3), pp. e0212757. Date of Electronic Publication: 2019 Mar 01 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Defective Viruses*/genetics
Defective Viruses*/immunology
Influenza A Virus, H1N1 Subtype*/genetics
Influenza A Virus, H1N1 Subtype*/immunology
Influenza A Virus, H3N2 Subtype*/genetics
Influenza A Virus, H3N2 Subtype*/immunology
Influenza, Human*/genetics
Influenza, Human*/immunology
Animals ; Chlorocebus aethiops ; Dogs ; HEK293 Cells ; Humans ; Madin Darby Canine Kidney Cells ; Vero Cells
Czasopismo naukowe
Tytuł :
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.
Autorzy :
Bruner KM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Molecular Biosciences, University of Texas, Austin, TX, USA.
Wang Z; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Simonetti FR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bender AM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kwon KJ; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sengupta S; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Fray EJ; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Beg SA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Antar AAR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jenike KM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bertagnolli LN; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Capoferri AA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kufera JT; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Timmons A; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Nobles C; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Gregg J; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Wada N; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ho YC; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, USA.
Zhang H; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Margolick JB; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Blankson JN; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Deeks SG; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Bushman FD; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Siliciano JD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Laird GM; Accelevir Diagnostics, Baltimore, MD, USA.
Siliciano RF; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Howard Hughes Medical Institute, Baltimore, MD, USA. .
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Źródło :
Nature [Nature] 2019 Feb; Vol. 566 (7742), pp. 120-125. Date of Electronic Publication: 2019 Jan 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Virus Latency*
CD4-Positive T-Lymphocytes/*virology
Carrier State/*virology
Defective Viruses/*isolation & purification
HIV Infections/*virology
HIV-1/*isolation & purification
Proviruses/*isolation & purification
CD4-Positive T-Lymphocytes/cytology ; Carrier State/therapy ; Cell Line ; DNA, Viral/analysis ; DNA, Viral/genetics ; Defective Viruses/genetics ; Defective Viruses/physiology ; HIV Infections/therapy ; HIV-1/genetics ; HIV-1/physiology ; Humans ; Lymphocyte Activation ; Polymerase Chain Reaction ; Proviruses/genetics ; Proviruses/physiology
Czasopismo naukowe
Tytuł :
Flu DRiPs in MHC Class I Immunosurveillance.
Autorzy :
Wei J; Cellular Biology Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Yewdell JW; Cellular Biology Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. .
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Źródło :
Virologica Sinica [Virol Sin] 2019 Apr; Vol. 34 (2), pp. 162-167. Date of Electronic Publication: 2018 Nov 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Monitoring, Immunologic*
Antigens, Viral/*immunology
Defective Viruses/*immunology
Influenza A virus/*immunology
Animals ; Antigens, Viral/genetics ; CD8-Positive T-Lymphocytes/immunology ; Defective Viruses/genetics ; Histocompatibility Antigens Class I/immunology ; Humans ; Influenza A virus/genetics ; Influenza, Human/immunology ; Influenza, Human/prevention & control ; Mice ; Peptides/genetics ; Peptides/immunology
Czasopismo naukowe
Tytuł :
OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential.
Autorzy :
Hein MD; Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Kollmus H; Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Marichal-Gallardo P; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Püttker S; Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Benndorf D; Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Genzel Y; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Schughart K; Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig, Germany.; University of Veterinary Medicine Hannover, Hannover, Germany.; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Kupke SY; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany. .
Reichl U; Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2021 Jan; Vol. 105 (1), pp. 129-146. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji :
Journal Article
MeSH Terms :
Animal Experimentation*
Influenza A virus*
Animals ; Antiviral Agents/pharmacology ; Defective Viruses ; Mice ; Virus Replication
Czasopismo naukowe

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