Autor: "Degawa, M." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Effects of Zinc Acetate Hydrate Supplementation on Renal Anemia with Hypozincemia in Hemodialysis Patients.
Autorzy:: Sato E; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Sato S; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Degawa M; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Ono T; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Lu H; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Matsumura D; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Nomura M; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Moriyama N; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Amaha M; Division of Nephrology, Department of Internal Medicine, Shinmatsudo Central General Hospital, Matsudo 270-0034, Japan.
Nakamura T; Department of Nephrology, Kashiwa Forest Clinic Kashiwa, Kashiwa 277-0042, Japan.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 Oct 31; Vol. 14 (11). Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Anemia*/drug therapy
Anemia*/etiology
Hematinics*/pharmacology
Hematinics*/therapeutic use
Kidney Failure, Chronic*/therapy
Kidney Diseases*
Male ; Humans ; Female ; Zinc Acetate/adverse effects ; Renal Dialysis/adverse effects ; Hemoglobins ; Zinc/therapeutic use ; Chronic Disease ; Dietary Supplements

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Skocz do pozycji: 2.

Tytuł:: Japan Flavour and Fragrance Materials Association's (JFFMA) safety assessment of food-flavouring substances uniquely used in Japan that belong to the class of aliphatic primary alcohols, aldehydes, carboxylic acids, acetals and esters containing additional oxygenated functional groups.
Autorzy:: Saito K; a Safety Assessment Division, Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Hasegawa-Baba Y; b Laboratory of Veterinary Pathology , Tokyo University of Agriculture and Technology , Tokyo , Japan.
Sekiya F; a Safety Assessment Division, Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Hayashi SM; a Safety Assessment Division, Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Mirokuji Y; a Safety Assessment Division, Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Okamura H; a Safety Assessment Division, Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Maruyama S; a Safety Assessment Division, Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Ono A; c Division of Risk Assessment , National Institute of Health Sciences , Tokyo , Japan.
Nakajima M; d Education and Research Department, School of Pharmaceutical Sciences , University of Shizuoka , Shizuoka , Japan.
Degawa M; e Department of Molecular Toxicology, School of Pharmaceutical Sciences , University of Shizuoka , Shizuoka , Japan.
Ozawa S; f Department of Pharmacodynamics and Molecular Genetics, School of Pharmacy , Iwate Medical University , Iwate , Japan.
Shibutani M; b Laboratory of Veterinary Pathology , Tokyo University of Agriculture and Technology , Tokyo , Japan.
Maitani T; g Division of Foods, National Institute of Health Sciences , Tokyo , Japan.; Pokaż więcej
Źródło:: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2017 Sep; Vol. 34 (9), pp. 1474-1484. Date of Electronic Publication: 2017 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Risk Assessment*
Flavoring Agents/*adverse effects
Flavoring Agents/*chemistry
Food Additives/*adverse effects
Food Additives/*chemistry
Acetals ; Alcohols ; Aldehydes ; Carboxylic Acids ; Esters ; Hazard Analysis and Critical Control Points ; Humans ; Japan ; Molecular Structure

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Skocz do pozycji: 3.

Tytuł:: Possible mechanism for the polychlorinated bipheny-linduced liver-selective accumulation of thyroxine in rats.
Autorzy:: Kato Y; Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University.
Fujii A; School of Pharmaceutical Sciences, University of Shizuoka.
Haraguchi K; Daiichi College of Pharmaceutical Sciences.
Fujii Y; Daiichi College of Pharmaceutical Sciences.
Atobe K; Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University.
Endo T; Faculty of Pharmaceutical Sciences, Health Science University of Hokkaido.
Kimura O; Faculty of Pharmaceutical Sciences, Health Science University of Hokkaido.
Koga N; Faculty of Nutritional Sciences, Nakamura Gakuen University.
Ohta C; Faculty of Nutritional Sciences, Nakamura Gakuen University.
Yamada S; School of Pharmaceutical Sciences, University of Shizuoka.
Degawa M; School of Pharmaceutical Sciences, University of Shizuoka.; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2017; Vol. 42 (6), pp. 663-669.
Typ publikacji:: Journal Article
MeSH Terms:: Liver/*metabolism
Polychlorinated Biphenyls/*adverse effects
Thyroxine/*metabolism
Animals ; Gene Expression/drug effects ; Male ; RNA, Messenger/metabolism ; Rats, Wistar ; Thyroxine-Binding Proteins/genetics ; Thyroxine-Binding Proteins/metabolism ; Time Factors ; Tissue Distribution

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Skocz do pozycji: 4.

Tytuł:: The Japan Flavour and Fragrance Materials Association's (JFFMA) safety assessment of acetal food flavouring substances uniquely used in Japan.
Autorzy:: Okamura H; a Japan Flavour and Fragrance Materials Association (JFFMA) , Tokyo , Japan.
Abe H
Hasegawa-Baba Y
Saito K
Sekiya F
Hayashi SM
Mirokuji Y
Maruyama S
Ono A
Nakajima M
Degawa M
Ozawa S
Shibutani M
Maitani T; Pokaż więcej
Źródło:: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2015; Vol. 32 (9), pp. 1384-96. Date of Electronic Publication: 2015 Aug 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Hazard Analysis and Critical Control Points*
Flavoring Agents/*adverse effects
Food Additives/*adverse effects
Flavoring Agents/chemistry ; Food Additives/chemistry ; Humans ; Japan ; Molecular Structure

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Skocz do pozycji: 5.

Tytuł:: Induced expression of hepatic N-methyl-D-aspartate receptor 2C subunit gene during liver enlargement induced by lead nitrate, a hepatocellular mitogen.
Autorzy:: Nemoto K; Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan. />Ikeda A
Hikida T
Kojima M
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2013 Feb; Vol. 38 (1), pp. 127-9.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hyperplasia/*metabolism
Lead/*toxicity
Liver/*drug effects
Mitogens/*toxicity
Nitrates/*toxicity
Receptors, N-Methyl-D-Aspartate/*genetics
Animals ; Gene Expression Regulation/drug effects ; Hyperplasia/chemically induced ; Hyperplasia/pathology ; Liver/metabolism ; Liver/pathology ; Male ; RNA, Messenger/metabolism ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY ; Rats, Sprague-Dawley

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Skocz do pozycji: 6.

Tytuł:: Change in the gene expression of the N-methyl-D-aspartate receptor 2C subunit by dietary β-naphthoflavone, indole-3-carbinol, or acetaminophen in the rat liver.
Autorzy:: Nemoto K; Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. />Ikeda A
Tanaka T
Inoue K
Yoshida M
Nishikawa A
Gamou T
Habano W
Ozawa S
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2013; Vol. 38 (4), pp. 611-7.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetaminophen/*pharmacology
Gene Expression/*drug effects
Hepatomegaly/*genetics
Indoles/*pharmacology
Liver/*metabolism
Receptors, N-Methyl-D-Aspartate/*genetics
beta-Naphthoflavone/*pharmacology
Animals ; Hepatomegaly/pathology ; Liver/drug effects ; Male ; Oligonucleotide Array Sequence Analysis ; Rats ; Rats, Inbred F344 ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors

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Skocz do pozycji: 7.

Tytuł:: Estrogen and androgen receptor status in hepatocellular hypertrophy induced by phenobarbital, clofibrate, and piperonyl butoxide in F344 rats.
Autorzy:: Fujimoto N; Department of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. />Inoue K
Yoshida M
Nishikawa A
Ozawa S
Gamou T
Nemoto K
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2012; Vol. 37 (2), pp. 281-6.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinogens/*toxicity
Estrogen Receptor alpha/*genetics
Hepatomegaly/*metabolism
Receptors, Androgen/*genetics
Animals ; CD36 Antigens/genetics ; Clofibrate/toxicity ; Female ; Hepatomegaly/chemically induced ; Hepatomegaly/pathology ; Leukemia Inhibitory Factor Receptor alpha Subunit/genetics ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Phenobarbital/toxicity ; Piperonyl Butoxide/toxicity ; RNA, Messenger/metabolism ; Rats ; Rats, Inbred F344

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Skocz do pozycji: 8.

Tytuł:: Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats.
Autorzy:: Ozawa S; Department of Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University, Iwate, Japan. />Gamou T
Habano W
Inoue K
Yoshida M
Nishikawa A
Nemoto K
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2011 Oct; Vol. 36 (5), pp. 613-23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Damage*/genetics
Cell Cycle Proteins/*genetics
Gene Expression/*drug effects
Hepatomegaly/*chemically induced
Liver/*drug effects
Liver Neoplasms, Experimental/*chemically induced
Nuclear Proteins/*genetics
Animals ; Clofibrate/toxicity ; Cytochrome P-450 Enzyme System/biosynthesis ; Down-Regulation ; Enzyme Induction ; Gene Expression Profiling ; Hepatomegaly/genetics ; Hepatomegaly/pathology ; Isoenzymes ; Liver/enzymology ; Liver/metabolism ; Liver/pathology ; Liver Neoplasms, Experimental/genetics ; Liver Neoplasms, Experimental/pathology ; Male ; Oligonucleotide Array Sequence Analysis ; Phenobarbital/toxicity ; Rats ; Rats, Inbred F344 ; Real-Time Polymerase Chain Reaction ; Time Factors ; Xenobiotics/toxicity

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Skocz do pozycji: 9.

Tytuł:: Super-induced gene expression of the N-methyl-D-aspartate receptor 2C subunit in chemical-induced hypertrophic liver in rats.
Autorzy:: Nemoto K; Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan. />Tanaka T
Ikeda A
Ito S
Mizukami M
Hikida T
Gamou T
Habano W
Ozawa S
Inoue K
Yoshida M
Nishikawa A
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2011 Oct; Vol. 36 (5), pp. 507-14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression/*drug effects
Hepatomegaly/*chemically induced
Receptors, N-Methyl-D-Aspartate/*genetics
Animals ; Clofibrate/toxicity ; Disease Models, Animal ; Hepatomegaly/genetics ; Hepatomegaly/pathology ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Oligonucleotide Array Sequence Analysis ; Organ Size/drug effects ; Phenobarbital/toxicity ; Piperonyl Butoxide/toxicity ; Rats ; Rats, Inbred F344 ; Reverse Transcriptase Polymerase Chain Reaction

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Skocz do pozycji: 10.

Tytuł:: Hepatic expression of spermatogenic genes and their transiently remarkable downregulations in Wistar-Kyoto rats in response to lead-nitrate administration: strain-difference in the gene expression patterns.
Autorzy:: Nemoto K; Department of Molecular Toxicology and Global COE Program, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan. />Ito S
Yoshida C
Miyata M
Kojima M
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2011 Jun; Vol. 36 (3), pp. 357-64.
Typ publikacji:: Journal Article
MeSH Terms:: Down-Regulation/*drug effects
Gene Expression/*drug effects
Lead/*toxicity
Liver/*drug effects
Nitrates/*toxicity
Spermatogenesis/*genetics
Animals ; Liver/metabolism ; Male ; Oligonucleotide Array Sequence Analysis ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY ; Rats, Sprague-Dawley ; Species Specificity

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Skocz do pozycji: 11.

Tytuł:: Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats.
Autorzy:: Sanada H; Department of Molecular Toxicology and Global Center of Excellence Program, School of Pharmaceutical Sciences, University of Shizuoka, Japan.
Sekimoto M
Kamoshita A
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2011 Apr; Vol. 36 (2), pp. 181-90.
Typ publikacji:: Journal Article
MeSH Terms:: Arthritis, Experimental/*enzymology
Cytochrome P-450 CYP2B1/*genetics
Cytochrome P-450 CYP3A/*genetics
Liver/*enzymology
Animals ; Arthritis, Experimental/genetics ; Cytochrome P-450 CYP2B1/metabolism ; Cytochrome P-450 CYP3A/metabolism ; Cytokines/genetics ; Cytokines/metabolism ; Gene Expression Regulation, Enzymologic ; Male ; Microsomes, Liver/drug effects ; Microsomes, Liver/enzymology ; RNA, Messenger/metabolism ; Rats ; Rats, Inbred Lew

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Skocz do pozycji: 12.

Tytuł:: Induction of hepatic cytochrome P450 isoforms by nicardipine at therapeutic doses in spontaneously hypertensive rats.
Autorzy:: Miyajima S; Department of Molecular Toxicology, COE Program in the 21st Century, School of Pharaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.
Nemoto K
Sekimoto M
Kinae Y
Kasahara T
Souma S
Degawa M; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2007 Feb; Vol. 32 (1), pp. 79-90.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antihypertensive Agents/*pharmacology
Aryl Hydrocarbon Hydroxylases/*drug effects
Calcium Channel Blockers/*pharmacology
Gene Expression/*drug effects
Hypertension/*enzymology
Nicardipine/*pharmacology
Animals ; Antihypertensive Agents/administration & dosage ; Aryl Hydrocarbon Hydroxylases/metabolism ; Calcium Channel Blockers/administration & dosage ; Dose-Response Relationship, Drug ; Enzyme Induction ; Male ; Nicardipine/administration & dosage ; Rats ; Rats, Inbred SHR

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Skocz do pozycji: 13.

Tytuł:: Species differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs.
Autorzy:: Haraguchi K; Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan. />Kato Y
Koga N
Degawa M; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2005 Jan; Vol. 35 (1), pp. 85-96.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Liver/*metabolism
Polychlorinated Biphenyls/*blood
Polychlorinated Biphenyls/*pharmacokinetics
Animals ; Cricetinae ; Guinea Pigs ; Male ; Mesocricetus ; Mice ; Mice, Inbred Strains ; Organ Specificity ; Rats ; Rats, Wistar ; Species Specificity