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Tytuł :
Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis.
Autorzy :
El-Naggar AM; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.; Department of Pathology, Faculty of Medicine, Menoufia University, Shibin El Kom, Egypt.
Somasekharan SP; Vancouver Prostate Centre, Vancouver, BC, Canada.
Wang Y; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Cheng H; Vancouver Prostate Centre, Vancouver, BC, Canada.
Negri GL; Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Pan M; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Wang XQ; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Delaidelli A; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Rafn B; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Cran J; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Zhang F; Vancouver Prostate Centre, Vancouver, BC, Canada.
Zhang H; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Colborne S; Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Gleave M; Vancouver Prostate Centre, Vancouver, BC, Canada.
Mandinova A; Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
Kedersha N; Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Hughes CS; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Surdez D; Centre de recherche de l'Institut Curie, Paris, France.
Delattre O; Centre de recherche de l'Institut Curie, Paris, France.
Wang Y; Vancouver Prostate Centre, Vancouver, BC, Canada.
Huntsman DG; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
Morin GB; Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Sorensen PH; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, Vancouver, BC, Canada.
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Źródło :
EMBO reports 2019 Dec 05; Vol. 20 (12), pp. e48375. Date of Electronic Publication: 2019 Oct 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Benzamides/*therapeutic use
Bone Neoplasms/*drug therapy
Histone Deacetylase Inhibitors/*therapeutic use
Pyridines/*therapeutic use
Sarcoma, Ewing/*drug therapy
Transcription Factors/*metabolism
Acetylation ; Animals ; Bone Neoplasms/metabolism ; Bone Neoplasms/pathology ; Cell Line, Tumor ; Cells, Cultured ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mice ; NF-E2-Related Factor 2/metabolism ; Neoplasm Metastasis ; Oxidative Stress ; Sarcoma, Ewing/metabolism ; Sarcoma, Ewing/pathology
Czasopismo naukowe
Tytuł :
Study of chromatin remodeling genes implicates SMARCA4 as a putative player in oncogenesis in neuroblastoma.
Autorzy :
Bellini A; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Bessoltane-Bentahar N; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Bhalshankar J; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Clement N; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Raynal V; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Plateforme de Séquençage ICGex, Institut Curie, Paris, France.
Baulande S; Institut Curie, PSL Research University, NGS Platform, Paris, France.
Bernard V; Department of Biopathology, Institut Curie, PSL Research University, Paris, France.
Danzon A; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Chicard M; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Colmet-Daage L; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Pierron G; Unité de Génétique Somatique, Institut Curie, Paris, France.
Le Roux L; Unité de Génétique Somatique, Institut Curie, Paris, France.
Planchon JM; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.; Department of Biopathology, Institut Curie, PSL Research University, Paris, France.
Combaret V; Laboratoire de Recherche Translationnelle, Centre Léon-Bérard, Lyon, France.
Lapouble E; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.; Unité de Génétique Somatique, Institut Curie, Paris, France.
Corradini N; Institut d'Hématologie et Oncologie Pédiatrique, Lyon, France.
Thebaud E; Service d'Oncologie Pédiatrique, Hôpital de la Mère et l'enfant, Nantes, France.
Gambart M; Unite d'Hemato-Oncologie, Hôpital des Enfants, Toulouse, France.
Valteau-Couanet D; Service d'Oncologie Pédiatrique, Institut Gustave Roussy, Paris, France.
Michon J; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Louis-Brennetot C; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Janoueix-Lerosey I; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Defachelles AS; Pediatric Oncology Unit, AntiCancer Center Oscar Lambret, Lille, France.
Bourdeaut F; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Delattre O; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Unité de Génétique Somatique, Institut Curie, Paris, France.
Schleiermacher G; Equipe SiRIC RTOP Recherche Translationelle en Oncologie Pédiatrique, Institut Curie, Paris, France.; INSERM U830, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
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Źródło :
International journal of cancer [Int J Cancer] 2019 Nov 15; Vol. 145 (10), pp. 2781-2791. Date of Electronic Publication: 2019 May 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenesis/*genetics
Chromatin Assembly and Disassembly/*genetics
DNA Helicases/*genetics
Neuroblastoma/*genetics
Nuclear Proteins/*genetics
Transcription Factors/*genetics
Adolescent ; Case-Control Studies ; Child ; Child, Preschool ; DNA Copy Number Variations ; Exons/genetics ; Female ; Germ-Line Mutation ; Humans ; INDEL Mutation ; Infant ; Infant, Newborn ; Kaplan-Meier Estimate ; Male ; Neuroblastoma/mortality ; Neuroblastoma/pathology ; Polymorphism, Single Nucleotide ; Progression-Free Survival ; Whole Exome Sequencing ; X-linked Nuclear Protein/genetics
Czasopismo naukowe
Tytuł :
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
Autorzy :
Lang XP; Suzhou Sano Precision Medicine Ltd, Suzhou, China.
Pan J; Children's Hospital of Soochow University, Suzhou, China.
Yang CX; Suzhou Sano Precision Medicine Ltd, Suzhou, China.
Chen P; Suzhou Sano Precision Medicine Ltd, Suzhou, China.
Shi CC; Suzhou Sano Precision Medicine Ltd, Suzhou, China.
Hong Y; Suzhou Sano Precision Medicine Ltd, Suzhou, China.
Wang J; Children's Hospital of Soochow University, Suzhou, China.
Xiao S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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Źródło :
Genes, chromosomes & cancer [Genes Chromosomes Cancer] 2020 May; Vol. 59 (5), pp. 325-329. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Renal Cell/*genetics
DNA-Binding Proteins/*genetics
Kidney Neoplasms/*genetics
Muscle Proteins/*genetics
Oncogene Proteins, Fusion/*genetics
RNA-Binding Protein EWS/*genetics
Transcription Factors/*genetics
Adult ; Biomarkers, Tumor/genetics ; Carcinoma, Renal Cell/pathology ; High-Throughput Nucleotide Sequencing/methods ; Humans ; In Situ Hybridization, Fluorescence/methods ; Kidney Neoplasms/pathology ; Male ; Translocation, Genetic
Czasopismo naukowe
Tytuł :
PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis.
Autorzy :
Kendall GC; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, United States.
Watson S; Institut Curie, Paris Sciences et Lettres (PSL) Research University, Inserm U830, Institut Curie, Paris Sciences et Lettres (PSL) Research University, Paris, France.
Xu L; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.
LaVigne CA; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, United States.
Murchison W; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.
Rakheja D; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.; Department of Pathology, UT Southwestern Medical Center, Dallas, United States.
Skapek SX; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.
Tirode F; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre LéonBérard, Lyon, France.
Delattre O; Institut Curie, Paris Sciences et Lettres (PSL) Research University, Inserm U830, Institut Curie, Paris Sciences et Lettres (PSL) Research University, Paris, France.; INSERM U80, Institute Curie Research Center, Paris, France.; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.
Amatruda JF; Department of Pediatrics, UT Southwestern Medical Center, Dallas, United States.; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, United States.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, United States.
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Źródło :
ELife [Elife] 2018 Jun 05; Vol. 7. Date of Electronic Publication: 2018 Jun 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenesis/*pathology
DNA-Binding Proteins/*metabolism
Rhabdomyosarcoma/*pathology
Transcription Factors/*metabolism
Zebrafish/*physiology
Animals ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; DNA-Binding Proteins/genetics ; Embryo, Nonmammalian/cytology ; Embryo, Nonmammalian/metabolism ; Forkhead Box Protein O1/genetics ; Forkhead Box Protein O1/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Muscle Development ; Myoblasts/metabolism ; Myoblasts/pathology ; PAX3 Transcription Factor/genetics ; PAX3 Transcription Factor/metabolism ; Rhabdomyosarcoma/genetics ; Rhabdomyosarcoma/metabolism ; Transcription Factors/genetics ; Zebrafish/metabolism
Czasopismo naukowe
Tytuł :
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.
Autorzy :
Boeva V; Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France.; Institut Cochin, Inserm U1016, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, University Paris Descartes UMR-S1016, Paris, France.
Louis-Brennetot C; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Peltier A; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Durand S; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Pierre-Eugène C; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Raynal V; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Etchevers HC; Aix Marseille University, INSERM, Génétique Médicale et Génomique Fonctionnelle (GMGF) UMR S910, Marseille, France.
Thomas S; INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris Descartes - Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Lermine A; Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France.
Daudigeos-Dubus E; Gustave Roussy, Vectorology and Anticancer Therapies, UMR 8203, CNRS, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
Geoerger B; Gustave Roussy, Vectorology and Anticancer Therapies, UMR 8203, CNRS, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Ludwig-Maximilians-Universität München (LMU), Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Ludwig-Maximilians-Universität München (LMU), Munich, Germany.
Diaz E; High Throughput qPCR Facility, Institut de Biologie de l'École Normale Supérieure (IBENS), PSL Research University, Paris, France.; LPS-ENS, Université Pierre et Marie Curie (UPMC), Université Denis Diderot, CNRS UMR 8550, PSL, Paris, France.
Ducos B; High Throughput qPCR Facility, Institut de Biologie de l'École Normale Supérieure (IBENS), PSL Research University, Paris, France.; LPS-ENS, Université Pierre et Marie Curie (UPMC), Université Denis Diderot, CNRS UMR 8550, PSL, Paris, France.; Laser Microdissection Facility, Center for Interdisciplinary Research in Biology (CIRB) Collège de France, Paris, France.
Surdez D; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Carcaboso AM; Institut de Recerca Sant Joan de Deu, Barcelona, Spain.
Medvedeva I; Institut Cochin, Inserm U1016, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, University Paris Descartes UMR-S1016, Paris, France.
Deller T; Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe University Frankfurt, Frankfurt am Main, Germany.
Combaret V; Centre Léon Bérard, Laboratoire de Recherche Translationnelle, Lyon, France.
Lapouble E; Institut Curie, Unité de Génétique Somatique, Paris, France.
Pierron G; Institut Curie, Unité de Génétique Somatique, Paris, France.
Grossetête-Lalami S; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Baulande S; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Schleiermacher G; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Laboratory Recherche Translationnelle en Oncologie Pédiatrique (RTOP), Laboratoire 'Gilles Thomas', Institut Curie, Paris, France.; Department of Translational Research, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Barillot E; Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France.
Rohrer H; Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe University Frankfurt, Frankfurt am Main, Germany.
Delattre O; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Janoueix-Lerosey I; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
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Źródło :
Nature genetics [Nat Genet] 2017 Sep; Vol. 49 (9), pp. 1408-1413. Date of Electronic Publication: 2017 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Lineage/*genetics
Gene Expression Regulation, Neoplastic/*genetics
Neuroblastoma/*genetics
Transcription Factors/*genetics
Animals ; Blotting, Western ; Cell Line, Tumor/classification ; Cell Lineage/drug effects ; Doxycycline/pharmacology ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic/drug effects ; Genetic Heterogeneity ; HEK293 Cells ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Humans ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Neuroblastoma/drug therapy ; Neuroblastoma/metabolism ; RNA Interference ; RNAi Therapeutics ; Reverse Transcriptase Polymerase Chain Reaction ; Single-Cell Analysis ; Transcription Factors/metabolism ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
SMARCA4-Mutated Atypical Teratoid/Rhabdoid Tumor with Retained BRG1 Expression.
Autorzy :
Masliah-Planchon J; Unité de génétique somatique, Institut Curie, Paris, France.; Inserm U830, Unité de Génétique et Biologie des Cancers, Institut Curie, Paris, France.
Machet MC; Département de pathologie, Université François Rabelais, Tours, France.
Fréneaux P; Département de pathologie, Institut Curie, Paris, France.
Jourdain A; Unité d'onco-hématologie pédiatrique, Hôpital de Clocheville, Tours, France.
Mortemousque I; Département de génétique, CHRU de Tours, hôpital Bretonneau, Tours, France.
Raïs KA; Unité de génétique somatique, Institut Curie, Paris, France.
Ballet S; Unité de génétique somatique, Institut Curie, Paris, France.
Jouvet A; Centre de pathologie Est et groupement hospitalier Est, Bron, France.
Figarella-Branger D; Service d'Anatomie Pathologique et de Neuropathologie, Hôpital de la Timone, APHM, Aix-Marseille Université, Marseille, France.
Delattre O; Inserm U830, Unité de Génétique et Biologie des Cancers, Institut Curie, Paris, France.
Bourdeaut F; Inserm U830, Unité de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; Département d'oncologie pédiatrique, Institut Curie, Paris, France.; SiRIC Institut Curie, Recherche Translationnelle en Oncologie Pédiatrique, Paris, France.
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Źródło :
Pediatric blood & cancer [Pediatr Blood Cancer] 2016 Mar; Vol. 63 (3), pp. 568-9. Date of Electronic Publication: 2015 Oct 15.
Typ publikacji :
Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
DNA Helicases/*analysis
DNA Helicases/*genetics
Infratentorial Neoplasms/*genetics
Nuclear Proteins/*analysis
Nuclear Proteins/*genetics
Rhabdoid Tumor/*genetics
Teratoma/*genetics
Transcription Factors/*analysis
Transcription Factors/*genetics
Child, Preschool ; Female ; Humans ; Infratentorial Neoplasms/diagnosis ; Rhabdoid Tumor/diagnosis ; Teratoma/diagnosis
SCR Disease Name :
Typical Teratoid Rhabdoid Tumor
Raport
Tytuł :
Oncologic Phenotype of Peripheral Neuroblastic Tumors Associated With PHOX2B Non-Polyalanine Repeat Expansion Mutations.
Autorzy :
Heide S; Service de Pathologie, Hôpital Robert Debré, APHP, Paris, France.
Masliah-Planchon J; INSERM U830, Génétique et Biologie des Cancers, Institut Curie, Paris, France.; Institut Curie, Unité de Génétique Somatique, Institut Curie, Paris, France.
Isidor B; Service de Génétique Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Guimier A; INSERM UMR 1163, Institut Imagine, Paris, France.
Bodet D; Unité d'Onco-Hématologie, Centre Hospitalier Universitaire de Caen, Caen, France.
Coze C; Service d'Oncologie Pédiatrique, Hôpital de la Timone, Centre Hospitalier Universitaire de Marseille, Marseille, France.
Deville A; Service d'Onco-Hématologie Pédiatrique, Centre Hospitalier Universitaire de Nice, Nice, France.
Thebault E; Service d'Onco-Hématologie Pédiatrique, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Pasquier CJ; Service d'Anatomie Pathologique, Centre Hospitalier Universitaire de Caen, Caen, France.
Cassagnau E; Service d'Anatomie Et Cytologie Pathologiques, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Pierron G; Institut Curie, Unité de Génétique Somatique, Institut Curie, Paris, France.
Clément N; Institut Curie, Unité de Génétique Somatique, Institut Curie, Paris, France.
Schleiermacher G; INSERM U830, Génétique et Biologie des Cancers, Institut Curie, Paris, France.; Institut Curie, Unité de Génétique Somatique, Institut Curie, Paris, France.
Amiel J; INSERM UMR 1163, Institut Imagine, Paris, France.; Sorbonne Paris Cite, Université Paris Descartes, Paris, France.; Service de Génétique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France.
Delattre O; INSERM U830, Génétique et Biologie des Cancers, Institut Curie, Paris, France.; Institut Curie, Unité de Génétique Somatique, Institut Curie, Paris, France.
Peuchmaur M; Service de Pathologie, Hôpital Robert Debré, APHP, Paris, France.; Sorbonne Paris Cite, Université Paris Diderot, Paris, France.
Bourdeaut F; INSERM U830, Génétique et Biologie des Cancers, Institut Curie, Paris, France.; Institut Curie, Département de pédiatrie-adolescent-jeunes adultes, Institut Curie, Paris, France.; Site de Recherche Intégrée en Cancérologie, Recherche Translationnelle en Oncologie Pédiatrique, Institut Curie, Paris, France.
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Źródło :
Pediatric blood & cancer [Pediatr Blood Cancer] 2016 Jan; Vol. 63 (1), pp. 71-7. Date of Electronic Publication: 2015 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Homeodomain Proteins/*genetics
Neuroblastoma/*genetics
Peripheral Nervous System Neoplasms/*genetics
Transcription Factors/*genetics
Adult ; Causality ; Child ; Child, Preschool ; Chromosome Aberrations ; DNA Repeat Expansion ; Ganglioneuroblastoma/genetics ; Ganglioneuroblastoma/pathology ; Ganglioneuroma/pathology ; Humans ; Hypothalamic Diseases/genetics ; Hypothalamic Diseases/pathology ; Hypoventilation/congenital ; Hypoventilation/genetics ; Hypoventilation/pathology ; Infant ; Mutation ; Neuroblastoma/pathology ; Neuroblastoma/therapy ; Nucleic Acid Hybridization ; Peripheral Nervous System Neoplasms/pathology ; Peripheral Nervous System Neoplasms/therapy ; Phenotype ; Prognosis ; Sleep Apnea, Central/genetics ; Sleep Apnea, Central/pathology ; Treatment Outcome
SCR Disease Name :
Congenital central hypoventilation syndrome
Czasopismo naukowe
Tytuł :
SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.
Autorzy :
Le Loarer F; Cancer Research Center of Lyon, INSERM U1052, Lyon, France.; Centre Leon Berard, Department of Pathology, Lyon, France.; Université Claude Bernard Lyon 1, Lyon, France.
Watson S; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.
Pierron G; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.
de Montpreville VT; Centre Chirurgical Marie Lannelongue, Department of Pathology, Le Plessis Robinson, France.
Ballet S; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.
Firmin N; Institut de Cancerologie de Montpellier, Department of Oncology, Montpellier, France.
Auguste A; Gustave Roussy, INSERM U981, Villejuif, France.
Pissaloux D; Centre Leon Berard, Department of Pathology, Lyon, France.
Boyault S; Centre Leon Berard, Department of Genetics, Lyon, France.
Paindavoine S; Centre Leon Berard, Department of Pathology, Lyon, France.
Dechelotte PJ; Centre Hospitalier Universitaire (CHU) de Clermont Ferrand, Department of Pathology, Clermont Ferrand, France.
Besse B; Gustave Roussy, Department of Cancer Medicine, Villejuif, France.; Université Paris Sud, Paris, France.
Vignaud JM; CHU Nancy, Department of Pathology, Nancy, France.
Brevet M; Université Claude Bernard Lyon 1, Lyon, France.; Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Pathology, Lyon, France.
Fadel E; Université Paris Sud, Paris, France.; Centre Chirurgical Marie Lannelongue, Department of Thoracic Surgery, Le Plessis Robinson, France.
Richer W; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; Site de Recherche Intégrée en Cancérologie (SiRIC) Institut Curie, Recherche Translationelle en Oncologie Pédiatrique (RTOP), Paris, France.
Treilleux I; Centre Leon Berard, Department of Pathology, Lyon, France.
Masliah-Planchon J; INSERM U830, Institut Curie Research Center, Paris, France.; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.
Devouassoux-Shisheboran M; Hospices Civils de Lyon, Hôpital de la Croix Rousse, Department of Pathology, Lyon, France.
Zalcman G; CHU Caen, Department of Pneumology and Thoracic Oncology, Caen, France.; Unité Mixte de Recherche (UMR) INSERM U186, Université Caen-Basse Normandie, Caen, France.
Allory Y; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, Plateforme de Ressources Biologiques, Creteil, France.; Université Paris-Est, Créteil, France.; INSERM U955, Institut Mondor de Recherche Biomédicale, Créteil, France.
Bourdeaut F; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.; Institut Curie, Département d'Oncologie Pédiatrique, Paris, France.
Thivolet-Bejui F; Université Claude Bernard Lyon 1, Lyon, France.; Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Pathology, Lyon, France.
Ranchere-Vince D; Centre Leon Berard, Department of Pathology, Lyon, France.
Girard N; Université Claude Bernard Lyon 1, Lyon, France.; Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Respiratory Medicine, Lyon, France.
Lantuejoul S; CHU Grenoble, Department of Pathology, Grenoble, France.; Université de Grenoble Joseph Fourier, Grenoble, France.
Galateau-Sallé F; CHU Caen, Department of Pathology, Caen, France.; INSERM U1086, Caen, France.
Coindre JM; Institut Bergonie, Department of Pathology, Bordeaux, France.; Université Bordeaux 2, Bordeaux, France.
Leary A; Gustave Roussy, INSERM U981, Villejuif, France.; Gustave Roussy, Department of Cancer Medicine, Villejuif, France.
Delattre O; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.
Blay JY; Cancer Research Center of Lyon, INSERM U1052, Lyon, France.; Université Claude Bernard Lyon 1, Lyon, France.; Centre Leon Berard, Department of Oncology, Lyon, France.
Tirode F; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.
Pokaż więcej
Źródło :
Nature genetics [Nat Genet] 2015 Oct; Vol. 47 (10), pp. 1200-5. Date of Electronic Publication: 2015 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription, Genetic*
DNA Helicases/*genetics
DNA-Binding Proteins/*genetics
Nuclear Proteins/*genetics
Sarcoma/*genetics
Thoracic Neoplasms/*genetics
Transcription Factors/*genetics
Adult ; Humans
Czasopismo naukowe
Tytuł :
SWI/SNF chromatin remodeling and human malignancies.
Autorzy :
Masliah-Planchon J; Unité de Génétique Somatique.
Bièche I
Guinebretière JM
Bourdeaut F
Delattre O
Pokaż więcej
Źródło :
Annual review of pathology [Annu Rev Pathol] 2015; Vol. 10, pp. 145-71. Date of Electronic Publication: 2014 Oct 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Chromatin Assembly and Disassembly/*physiology
Chromosomal Proteins, Non-Histone/*genetics
Chromosomal Proteins, Non-Histone/*metabolism
Neoplasms/*genetics
Neoplasms/*metabolism
Transcription Factors/*genetics
Transcription Factors/*metabolism
Animals ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
Conventional chondrosarcoma in a survivor of rhabdoid tumor: enlarging the spectrum of tumors associated with SMARCB1 germline mutations.
Autorzy :
Forest F; Département de Pathologie, Centre Hospitalier.
David A
Arrufat S
Pierron G
Ranchere-Vince D
Stephan JL
Clemenson A
Delattre O
Bourdeaut F
Pokaż więcej
Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2012 Dec; Vol. 36 (12), pp. 1892-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Germ-Line Mutation*
Biomarkers, Tumor/*genetics
Chondrosarcoma/*genetics
Chromosomal Proteins, Non-Histone/*genetics
DNA-Binding Proteins/*genetics
Mandibular Neoplasms/*genetics
Neoplasms, Second Primary/*genetics
Rhabdoid Tumor/*genetics
Thoracic Neoplasms/*genetics
Transcription Factors/*genetics
Adolescent ; Biomarkers, Tumor/analysis ; Child ; Chondrosarcoma/chemistry ; Chondrosarcoma/pathology ; Chondrosarcoma/therapy ; Chromosomal Proteins, Non-Histone/analysis ; DNA Mutational Analysis ; DNA-Binding Proteins/analysis ; Exons ; Gene Deletion ; Genetic Predisposition to Disease ; Humans ; Immunohistochemistry ; Magnetic Resonance Imaging ; Male ; Mandibular Neoplasms/chemistry ; Mandibular Neoplasms/pathology ; Mandibular Neoplasms/therapy ; Neoplasms, Second Primary/chemistry ; Neoplasms, Second Primary/pathology ; Neoplasms, Second Primary/therapy ; Rhabdoid Tumor/chemistry ; Rhabdoid Tumor/pathology ; Rhabdoid Tumor/therapy ; SMARCB1 Protein ; Thoracic Neoplasms/chemistry ; Thoracic Neoplasms/pathology ; Thoracic Neoplasms/therapy ; Tomography, X-Ray Computed ; Transcription Factors/analysis
Czasopismo naukowe
Tytuł :
PHOX2B immunolabeling: a novel tool for the diagnosis of undifferentiated neuroblastomas among childhood small round blue-cell tumors.
Autorzy :
Bielle F; APHP, Hôpital Robert Debré, Service de Pathologie, Paris, France.
Fréneaux P
Jeanne-Pasquier C
Maran-Gonzalez A
Rousseau A
Lamant L
Paris R
Pierron G
Nicolas AV
Sastre-Garau X
Delattre O
Bourdeaut F
Peuchmaur M
Pokaż więcej
Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2012 Aug; Vol. 36 (8), pp. 1141-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*analysis
Homeodomain Proteins/*analysis
Neuroblastoma/*diagnosis
Transcription Factors/*analysis
Adolescent ; Child ; Comparative Genomic Hybridization ; Cytological Techniques ; Ganglioneuroblastoma/diagnosis ; Ganglioneuroma/diagnosis ; Homeodomain Proteins/biosynthesis ; Humans ; Immunohistochemistry ; Microarray Analysis ; Neuroblastoma/chemistry ; Neuroblastoma/genetics ; Neuroblastoma/metabolism ; Oligonucleotide Array Sequence Analysis ; RNA, Messenger/analysis ; Sensitivity and Specificity ; Transcription Factors/biosynthesis ; Young Adult
Czasopismo naukowe
Tytuł :
SMARCB1 deficiency in tumors from the peripheral nervous system: a link between schwannomas and rhabdoid tumors?
Autorzy :
Rizzo D; Department of Pediatric Oncology, Catholic University, A. Gemelli Hospital, Rome, Italy.
Fréneaux P
Brisse H
Louvrier C
Lequin D
Nicolas A
Ranchère D
Verkarre V
Jouvet A
Dufour C
Edan C
Stéphan JL
Orbach D
Sarnacki S
Pierron G
Parfait B
Peuchmaur M
Delattre O
Bourdeaut F
Pokaż więcej
Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2012 Jul; Vol. 36 (7), pp. 964-72.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Silencing*
Biomarkers, Tumor/*genetics
Chromosomal Proteins, Non-Histone/*genetics
DNA-Binding Proteins/*genetics
Neurilemmoma/*genetics
Peripheral Nervous System Neoplasms/*genetics
Rhabdoid Tumor/*genetics
Transcription Factors/*genetics
Biomarkers, Tumor/analysis ; Child ; Child, Preschool ; Chromosomal Proteins, Non-Histone/analysis ; DNA-Binding Proteins/analysis ; Female ; Gene Deletion ; Genes, Neurofibromatosis 2 ; Genetic Predisposition to Disease ; Hemizygote ; Humans ; Immunohistochemistry ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neurilemmoma/chemistry ; Neurilemmoma/pathology ; Paris ; Peripheral Nervous System Neoplasms/chemistry ; Peripheral Nervous System Neoplasms/pathology ; Phenotype ; Predictive Value of Tests ; Rhabdoid Tumor/chemistry ; Rhabdoid Tumor/pathology ; SMARCB1 Protein ; Sequence Analysis, DNA ; Transcription Factors/analysis
Czasopismo naukowe
Tytuł :
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
Autorzy :
Cho YJ; Children's Hospital Boston, Boston, MA 02115, USA.
Tsherniak A
Tamayo P
Santagata S
Ligon A
Greulich H
Berhoukim R
Amani V
Goumnerova L
Eberhart CG
Lau CC
Olson JM
Gilbertson RJ
Gajjar A
Delattre O
Kool M
Ligon K
Meyerson M
Mesirov JP
Pomeroy SL
Pokaż więcej
Źródło :
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2011 Apr 10; Vol. 29 (11), pp. 1424-30. Date of Electronic Publication: 2010 Nov 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cerebellar Neoplasms/*genetics
Cerebellar Neoplasms/*pathology
DNA-Binding Proteins/*genetics
Medulloblastoma/*genetics
Medulloblastoma/*pathology
Transcription Factors/*genetics
Algorithms ; Child ; Gene Expression Regulation, Neoplastic ; Genomics ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Polymorphism, Single Nucleotide ; Predictive Value of Tests ; Prognosis ; RNA, Neoplasm/genetics
Czasopismo naukowe
Tytuł :
De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis.
Autorzy :
Boeva V; Institut Curie, 26 rue d'Ulm, Paris, France.
Surdez D
Guillon N
Tirode F
Fejes AP
Delattre O
Barillot E
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2010 Jun; Vol. 38 (11), pp. e126. Date of Electronic Publication: 2010 Apr 07.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Regulatory Elements, Transcriptional*
Sequence Analysis, DNA*
Chromatin Immunoprecipitation/*methods
Transcription Factors/*metabolism
Base Sequence ; Binding Sites ; Cell Line, Tumor ; Consensus Sequence ; Humans ; Oncogene Proteins, Fusion/metabolism ; Proto-Oncogene Protein c-fli-1/metabolism ; RNA-Binding Protein EWS
Czasopismo naukowe
Tytuł :
Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.
Autorzy :
Le Deley MC; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Zimmermannplatz 10, 1090 Vienna, Austria.
Delattre O
Schaefer KL
Burchill SA
Koehler G
Hogendoorn PC
Lion T
Poremba C
Marandet J
Ballet S
Pierron G
Brownhill SC
Nesslböck M
Ranft A
Dirksen U
Oberlin O
Lewis IJ
Craft AW
Jürgens H
Kovar H
Pokaż więcej
Źródło :
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2010 Apr 20; Vol. 28 (12), pp. 1982-8. Date of Electronic Publication: 2010 Mar 22.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Bone Neoplasms/*genetics
Oncogene Proteins, Fusion/*genetics
Proto-Oncogene Protein c-fli-1/*genetics
Sarcoma, Ewing/*genetics
Transcription Factors/*genetics
Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biopsy ; Bone Neoplasms/mortality ; Bone Neoplasms/pathology ; Bone Neoplasms/therapy ; Chi-Square Distribution ; Disease Progression ; Europe ; Female ; Genetic Predisposition to Disease ; Humans ; Kaplan-Meier Estimate ; Male ; Neoplasm Recurrence, Local ; Paraffin Embedding ; Phenotype ; Proportional Hazards Models ; Prospective Studies ; RNA-Binding Protein EWS ; Radiotherapy, Adjuvant ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Assessment ; Risk Factors ; Sarcoma, Ewing/mortality ; Sarcoma, Ewing/secondary ; Sarcoma, Ewing/therapy ; Stem Cell Transplantation ; Time Factors ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
[Rhadboid tumours: hSNF/INI1 deficient cancers of early childhood with aggressive behaviour].
Autorzy :
Bourdeaut F; CHU de Nantes, Service d'Oncohématologie, 4 Quai Moncousu, 44000 Nantes Cedex, France. />Dufour C
Delattre O
Pokaż więcej
Transliterated Title :
Les tumeurs rhabdoïdes : des tumeurs hSNF5/INI1-déficientes précoces et agressives.
Źródło :
Bulletin du cancer [Bull Cancer] 2010 Jan; Vol. 97 (1), pp. 37-45.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Silencing*
Chromosomal Proteins, Non-Histone/*genetics
DNA-Binding Proteins/*genetics
Neoplasm Proteins/*genetics
Rhabdoid Tumor/*genetics
Transcription Factors/*genetics
Central Nervous System Neoplasms/diagnosis ; Central Nervous System Neoplasms/therapy ; Chromosomal Proteins, Non-Histone/metabolism ; Chromosomes, Human, Pair 22/genetics ; DNA-Binding Proteins/metabolism ; Diagnosis, Differential ; Genes, Tumor Suppressor ; Germ-Line Mutation ; Humans ; Infant ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/therapy ; Liver Neoplasms/diagnosis ; Liver Neoplasms/therapy ; Neoplasm Proteins/metabolism ; Rhabdoid Tumor/diagnosis ; Rhabdoid Tumor/metabolism ; Rhabdoid Tumor/therapy ; SMARCB1 Protein ; Soft Tissue Neoplasms/diagnosis ; Soft Tissue Neoplasms/therapy ; Transcription Factors/metabolism ; Wilms Tumor/diagnosis ; Wilms Tumor/therapy
Czasopismo naukowe
Tytuł :
DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome.
Autorzy :
Lepagnol-Bestel AM; INSERM U675, IFR02, Faculté de Médecine Xavier Bichat, Université Paris Diderot-Paris 7, Paris, France.
Zvara A
Maussion G
Quignon F
Ngimbous B
Ramoz N
Imbeaud S
Loe-Mie Y
Benihoud K
Agier N
Salin PA
Cardona A
Khung-Savatovsky S
Kallunki P
Delabar JM
Puskas LG
Delacroix H
Aggerbeck L
Delezoide AL
Delattre O
Gorwood P
Moalic JM
Simonneau M
Pokaż więcej
Źródło :
Human molecular genetics [Hum Mol Genet] 2009 Apr 15; Vol. 18 (8), pp. 1405-14. Date of Electronic Publication: 2009 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromatin Assembly and Disassembly*
Chromosomal Proteins, Non-Histone/*metabolism
Down Syndrome/*genetics
Down Syndrome/*physiopathology
Protein-Serine-Threonine Kinases/*metabolism
Protein-Tyrosine Kinases/*metabolism
Repressor Proteins/*metabolism
Transcription Factors/*metabolism
Animals ; Brain/cytology ; Brain/metabolism ; Cells, Cultured ; Dendrites/physiology ; Mice ; Neurons/metabolism ; Protein-Serine-Threonine Kinases/genetics ; Protein-Tyrosine Kinases/genetics ; Transfection
Czasopismo naukowe
Tytuł :
RhoA-dependent regulation of cell migration by the tumor suppressor hSNF5/INI1.
Autorzy :
Caramel J; Institut Curie and Institut National de la Santé et de la Recherche Medicale U830, Unité de Génétique et Biologie des Cancers, Paris, France.
Quignon F
Delattre O
Pokaż więcej
Źródło :
Cancer research [Cancer Res] 2008 Aug 01; Vol. 68 (15), pp. 6154-61.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement/*physiology
Chromosomal Proteins, Non-Histone/*physiology
DNA-Binding Proteins/*physiology
Transcription Factors/*physiology
rhoA GTP-Binding Protein/*physiology
Base Sequence ; Cell Line ; Chromosomal Proteins, Non-Histone/genetics ; DNA Primers ; DNA-Binding Proteins/genetics ; Fluorescent Antibody Technique ; Humans ; Reverse Transcriptase Polymerase Chain Reaction ; SMARCB1 Protein ; Transcription Factors/genetics
Czasopismo naukowe

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