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Tytuł :
Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy-the MecMeth/NOA-24 trial.
Autorzy :
Zeyen T; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Potthoff AL; Department of Neurosurgery and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Nemeth R; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.
Heiland DH; Department of Neurosurgery, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Burger MC; Dr. Senckenberg Institute of Neurooncology, Goethe-University Hospital, Frankfurt am Main, Germany.
Steinbach JP; Dr. Senckenberg Institute of Neurooncology, Goethe-University Hospital, Frankfurt am Main, Germany.
Hau P; Department of Neurology and Wilhelm Sander-NeuroOncology Unit, University Hospital Regensburg, Regensburg, Germany.
Tabatabai G; Interdisciplinary Division of Neurooncology, University of Tübingen, Tübingen, Germany.
Glas M; Division of Clinical Neurooncology, Department of Neurology, University Hospital Essen, Essen, Germany.
Schlegel U; Department of Neurology, University Hospital Knappschaftskrankenhaus, Ruhr-Universität Bochum, Bochum, Germany.
Grauer O; Department of Neurology, University of Münster, Münster, Germany.
Krex D; Department of Neurosurgery, University of Dresden, Dresden, Germany.
Schnell O; Department of Neurosurgery, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Goldbrunner R; Department of Neurosurgery, University of Cologne, Cologne, Germany.
Sabel M; Department of Neurosurgery, University of Düsseldorf, Düsseldorf, Germany.
Thon N; Department of Neurosurgery, Ludwig Maximillian University of Munich and German Cancer Consortium, Partner Site Munich, Munich, Germany.
Delev D; Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.
Clusmann H; Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.
Seidel C; Department of Radiotherapy and Radiation Oncology, University of Leipzig, Leipzig, Germany.
Güresir E; Department of Neurosurgery and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Schmid M; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.
Schuss P; Department of Neurosurgery and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Giordano FA; Department of Radiation Oncology, University Hospital Bonn, Bonn, Germany.
Radbruch A; Department of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Becker A; Department of Neuropathology, University Hospital Bonn, Bonn, Germany.
Weller J; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Schaub C; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Vatter H; Department of Neurosurgery and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Schilling J; Clinical Study Core Unit Bonn, Institute of Clinical Chemistry and Clinical Pharmacology, University Bonn, Bonn, Germany.
Winkler F; Department of Neurology, University Hospital Heidelberg, Neurooncology Program at the National Center for Tumor Disease, German Cancer Consortium (DKTK), Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Herrlinger U; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Schneider M; Department of Neurosurgery and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany. .
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Źródło :
Trials [Trials] 2022 Jan 19; Vol. 23 (1), pp. 57. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
MeSH Terms :
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Antineoplastic Agents, Alkylating/adverse effects ; DNA Modification Methylases/therapeutic use ; DNA Repair Enzymes/genetics ; DNA Repair Enzymes/therapeutic use ; Humans ; Meclofenamic Acid/therapeutic use ; Neoplasm Recurrence, Local ; Temozolomide/adverse effects ; Tumor Suppressor Proteins/therapeutic use
Czasopismo naukowe
Tytuł :
Value of ultra-high field MRI in patients with suspected focal epilepsy and negative 3 T MRI (EpiUltraStudy): protocol for a prospective, longitudinal therapeutic study.
Autorzy :
van Lanen RHGJ; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands. .; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands. .
Wiggins CJ; Scannexus, Ultra-High Field MRI Research Center, Maastricht, the Netherlands.
Colon AJ; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.
Backes WH; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Jansen JFA; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands.; Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Uher D; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Drenthen GS; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Roebroeck A; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Ivanov D; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Poser BA; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Hoeberigs MC; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands.
van Kuijk SMJ; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, Maastricht, the Netherlands.
Hoogland G; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.
Rijkers K; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.
Wagner GL; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.
Beckervordersandforth J; Department of Pathology, Maastricht University Medical Center, Maastricht, the Netherlands.
Delev D; Department of Neurosurgery, RWTH Aachen University Hospital, Aachen, Germany.
Clusmann H; Department of Neurosurgery, RWTH Aachen University Hospital, Aachen, Germany.
Wolking S; Department of Epileptology and Neurology, RWTH Aachen University Hospital, Aachen, Germany.
Klinkenberg S; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.; Department of Neurology, Maastricht University Medical Center, Maastricht, the Netherlands.
Rouhl RPW; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.; Department of Neurology, Maastricht University Medical Center, Maastricht, the Netherlands.
Hofman PAM; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Schijns OEMG; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Center, Heeze/Maastricht, the Netherlands.
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Źródło :
Neuroradiology [Neuroradiology] 2022 Jan 05. Date of Electronic Publication: 2022 Jan 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Machine Learning-Based Radiomics in Neuro-Oncology.
Autorzy :
Ehret F; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Radiation Oncology, Berlin, Germany.; European Cyberknife Center Munich, Munich, Germany.
Kaul D; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Radiation Oncology, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Clusmann H; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Delev D; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.
Kernbach JM; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany. .; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany. .
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Źródło :
Acta neurochirurgica. Supplement [Acta Neurochir Suppl] 2022; Vol. 134, pp. 139-151.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Artificial Intelligence*
Brain Neoplasms*/diagnostic imaging
Brain ; Humans ; Machine Learning ; Multicenter Studies as Topic
Czasopismo naukowe
Tytuł :
Dimensionality Reduction: Foundations and Applications in Clinical Neuroscience.
Autorzy :
Kernbach JM; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany. .; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany. .
Ort J; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Hakvoort K; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Clusmann H; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Delev D; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Neuloh G; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
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Źródło :
Acta neurochirurgica. Supplement [Acta Neurochir Suppl] 2022; Vol. 134, pp. 59-63.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Neuroimaging*
Brain/diagnostic imaging ; Humans ; Machine Learning ; Principal Component Analysis
Czasopismo naukowe
Tytuł :
Introduction to Machine Learning in Neuroimaging.
Autorzy :
Kernbach JM; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany. .; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany. .
Ort J; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Hakvoort K; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Clusmann H; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Neuloh G; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Delev D; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
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Źródło :
Acta neurochirurgica. Supplement [Acta Neurochir Suppl] 2022; Vol. 134, pp. 121-124.
Typ publikacji :
Journal Article
MeSH Terms :
Machine Learning*
Neuroimaging*
Algorithms ; Cluster Analysis
Czasopismo naukowe
Tytuł :
Analysis of biometric parameters of 2340 eyes measured with optical biometer Lenstar LS900 in a Caucasian population.
Autorzy :
Popov I; Department of Ophthalmology, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Waczulikova I; Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava, Slovakia.
Stefanickova J; Department of Ophthalmology, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Valaskova J; Department of Ophthalmology, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Tomcikova D; Department of Pediatric Ophthalmology, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Shiwani HA; Royal Lancaster Infirmary, University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, UK.
Delev D; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.
Rodrigo L; Faculty of Medicine, University of Oviedo, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
Saxena S; Department of Ophthalmology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Kruzliak P; Department of Internal Medicine, Brothers of Mercy Hospital, Brno, Czech Republic.
Krasnik V; Department of Ophthalmology, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
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Źródło :
European journal of ophthalmology [Eur J Ophthalmol] 2022 Jan; Vol. 32 (1), pp. 213-220. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cataract*/diagnosis
Lens, Crystalline*
Aged ; Anterior Chamber ; Axial Length, Eye ; Biometry ; Cornea ; Female ; Humans ; Male ; Retrospective Studies ; Tomography, Optical Coherence
Czasopismo naukowe
Tytuł :
Foundations of Time Series Analysis.
Autorzy :
Ort J; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.
Hakvoort K; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.
Neuloh G; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Clusmann H; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Delev D; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.
Kernbach JM; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany. .; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany. .
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Źródło :
Acta neurochirurgica. Supplement [Acta Neurochir Suppl] 2022; Vol. 134, pp. 215-220.
Typ publikacji :
Journal Article
MeSH Terms :
Machine Learning*
Models, Statistical*
Forecasting ; Time Factors
Czasopismo naukowe
Tytuł :
The Artificial Intelligence Doctor: Considerations for the Clinical Implementation of Ethical AI.
Autorzy :
Kernbach JM; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany. .; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany. .
Hakvoort K; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Ort J; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Clusmann H; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Neuloh G; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Delev D; Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital, Aachen, Germany.; Department of Neurosurgery, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
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Źródło :
Acta neurochirurgica. Supplement [Acta Neurochir Suppl] 2022; Vol. 134, pp. 257-261.
Typ publikacji :
Journal Article
MeSH Terms :
Artificial Intelligence*
Machine Learning*
Czasopismo naukowe
Tytuł :
Enhancing Safety in Epilepsy Surgery (EASINESS): Study Protocol for a Retrospective, Multicenter, Open Registry.
Autorzy :
Drexler R; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ben-Haim S; Department of Neurosurgery, University of California San Diego, San Diego, CA, United States.
Bien CG; Epilepsy Centre Bethel, Krankenhaus Mara, Bielefeld, Germany.
Borger V; Department of Neurosurgery, University Hospital Bonn, Bonn, Germany.
Cardinale F; 'C. Munari' Epilepsy Surgery Center, Niguarda Hospital, Milan, Italy.
Carpentier A; Department of Neurosurgery, Pitié-Salpêtrière Hospital, Paris, France.
Cendes F; Department of Neurology, University of Campinas, Campinas, Brazil.
Chandra S; Department of Neurosurgery, AIIMS, New Delhi, India.
Clusmann H; Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.
Colon A; School for Mental Health and Neuroscience (MHeNS), University Maastricht (UM), Maastricht, Netherlands.
de Curtis M; Epilepsy Unit, IRCCS 'C. Besta' Neurological Institute Foundation, Milan, Italy.
Delev D; Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.
Didato G; Epilepsy Unit, IRCCS 'C. Besta' Neurological Institute Foundation, Milan, Italy.
Dührsen L; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Farah JO; The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.
Guenot M; Department of Functional Neurosurgery, P. Wertheimer Hospital, Hospices Civils de Lyon, Lyon, France.; Department for Neurosurgery, University of Lyon, Lyon, France.
Ghatan S; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Haegelen C; Department of Functional Neurosurgery, P. Wertheimer Hospital, Hospices Civils de Lyon, Lyon, France.; Department for Neurosurgery, University of Lyon, Lyon, France.
Hamer H; Epilepsy Center, Department of Neurology, University of Erlangen-Nürnberg, Erlangen, Germany.
Hauptmann JS; Department of Neurosurgery, University of Washington, Seattle, WA, United States.
Jeffree RL; Department of Neurosurgery, Royal Brisbane and Womens Hospital, Brisbane, QLD, Australia.; Herston Clinical School, University of Queensland, Brisbane, QLD, Australia.
Kalbhenn T; Department of Neurosurgery (Evangelisches Klinikum Bethel), Bielefeld University, Medical School, Bielefeld, Germany.
Kegele J; Department of Neurology and Epileptology, Hertie Institute of Clinical Brain Research, University of Tubingen, Tubingen, Germany.
Krayenbühl N; Division of Pediatric Neurosurgery, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Lang J; Epilepsy Center, Department of Neurology, University of Erlangen-Nürnberg, Erlangen, Germany.
Mathon B; Department of Neurosurgery, Pitié-Salpêtrière Hospital, Paris, France.
Naros G; Department of Neurology and Epileptology, Hertie Institute of Clinical Brain Research, University of Tubingen, Tubingen, Germany.
Onken J; Department of Neurosurgery, Universitätsmedizin Charité-Berlin, Berlin, Germany.
Panov F; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Raftopoulos C; Department of Neurosurgery, University Hospital St-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Ricklefs FL; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rijkers K; Department of Neurosurgery, Academic Center for Epileptology UMC Maastricht, Maastricht, Netherlands.
Rizzi M; Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Rössler K; Department of Neurosurgery, Medical University Vienna, Vienna, Austria.
Schijns O; Department of Neurosurgery, Academic Center for Epileptology UMC Maastricht, Maastricht, Netherlands.; School for Mental Health and Neuroscience (MHeNS), University Maastricht (UM), Maastricht, Netherlands.
Schneider UC; Department of Neurosurgery, Universitätsmedizin Charité-Berlin, Berlin, Germany.
Spyrantis A; Department of Neurosurgery and Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt, Germany.
Strzelczyk A; Department of Neurosurgery and Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt, Germany.
Stodieck S; Hamburg Epilepsy Center, Protestant Hospital Alsterdorf, Department of Neurology and Epileptology, Hamburg, Germany.
Tripathi M; Department of Neurosurgery, AIIMS, New Delhi, India.
Vadera S; Department of Neurological Surgery, University of California Irvine, Irvine, CA, United States.
Alonso-Vanegas MA; National Institute of Neurology and Neurosurgery, Manuel Velasco Suarez, Mexico City, Mexico.
Vaz JGR; Department of Neurosurgery, University Hospital St-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.
Wellmer J; Ruhr - Epileptology, Department of Neurology, University Hospital Knappschafts-Krankenhaus, Ruhr - University Bochum, Bochum, Germany.
Wehner T; Ruhr - Epileptology, Department of Neurology, University Hospital Knappschafts-Krankenhaus, Ruhr - University Bochum, Bochum, Germany.
Westphal M; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sauvigny T; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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Źródło :
Frontiers in neurology [Front Neurol] 2021 Dec 13; Vol. 12, pp. 782666. Date of Electronic Publication: 2021 Dec 13 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Comparison of the real-world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug-resistant epilepsy: A post hoc analysis of the HOPS study.
Autorzy :
Fallah A; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Lewis E; Neurology Center of Toronto, Toronto, Ontario, Canada.
Ibrahim GM; Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Kola O; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Tseng CH; Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Harris WB; Department of Medicine, John A. Burns School of Medicine at University of Hawaii, Honolulu, Hawaii, USA.
Chen JS; Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Lin KM; Department of Functional Neurosurgery, Xiamen Humanity Hospital, Xiamen, China.
Cai LX; Department of Pediatric Epilepsy Center, Peking University First Hospital, Beijing, China.
Liu QZ; Department of Pediatric Epilepsy Center, Peking University First Hospital, Beijing, China.
Lin JL; Department of Epilepsy Center, Yuquan Hospital, Tsinghua University, Beijing, China.
Zhou WJ; Department of Epilepsy Center, Yuquan Hospital, Tsinghua University, Beijing, China.
Mathern GW; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Smyth MD; Department of Neurological Surgery, St. Louis Children's Hospital, St. Louis, Missouri, USA.
O'Neill BR; Department of Neurosurgery, Children's Hospital Colorado, Aurora, Colorado, USA.
Dudley RWR; Division of Neurosurgery, Department of Pediatric Surgery, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Ragheb J; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, Florida, USA.
Bhatia S; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, Florida, USA.
Delev D; Department of Neurosurgery, University Medical Center Freiburg and Medical Faculty, University of Freiburg, Freiburg, Germany.
Ramantani G; Department of Neurosurgery, University Medical Center Freiburg and Medical Faculty, University of Freiburg, Freiburg, Germany.; Department of Neuropediatrics, University Children's Hospital Zurich, Zurich, Switzerland.
Zentner J; Department of Neurosurgery, University Medical Center Freiburg and Medical Faculty, University of Freiburg, Freiburg, Germany.
Wang AC; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Dorfer C; Department of Neurosurgery, Medical University Vienna, Vienna, Austria.
Feucht M; Department of Pediatrics, Medical University Vienna, Vienna, Austria.
Czech T; Department of Neurosurgery, Medical University Vienna, Vienna, Austria.
Bollo RJ; Division of Pediatric Neurosurgery, Department of Neurosurgery, Primary Children's Hospital, Salt Lake City, Utah, USA.
Issabekov G; Department of Functional Neurosurgery, Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zhu H; Department of Functional Neurosurgery, Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Connolly M; Division of Neurosurgery, Department of Surgery, BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.
Steinbok P; Division of Neurosurgery, Department of Surgery, BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.
Zhang JG; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang K; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hidalgo ET; Division of Pediatric Neurosurgery, Department of Surgery, Hassenfeld Children's Hospital, NYU Langone Health, New York, New York, USA.
Weiner HL; Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.
Wong-Kisiel L; Division of Child Neurology and Epilepsy, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Lapalme-Remis S; Division of Neurology, Department of Medicine, University of Montreal Hospital Centre, Montreal, Quebec, Canada.
Tripathi M; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
Sarat Chandra P; Department of Neurosurgery (Center of Excellence for Epilepsy & Magnetoencephalography), All India Institute of Medical Sciences and National Brain Research Center, New Delhi, India.
Hader W; Division of Neurosurgery, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Wang FP; Department of Functional Neurosurgery, Xiamen Humanity Hospital, Xiamen, China.
Yao Y; Department of Neurosurgery, Guangdong Shenzhen Children Hospital, Shenzhen, China.
Champagne PO; Department of Neurosurgery, Saint Justine University Hospital Centre, Montreal, Quebec, Canada.
Brunette-Clément T; Department of Neurosurgery, Saint Justine University Hospital Centre, Montreal, Quebec, Canada.
Guo Q; Department of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou Shi, China.
Li SC; Department of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou Shi, China.
Budke M; Department of Neurosurgery, Niño Jesus University Children's Hospital, Madrid, Spain.
Pérez-Jiménez MA; Department of Neurophysiology, Niño Jesus University Children's Hospital, Madrid, Spain.
Raftopoulos C; Department of Neurosurgery, Brussels Saint-Luc University Hospital, Brussels, Belgium.
Finet P; Department of Neurosurgery, Brussels Saint-Luc University Hospital, Brussels, Belgium.
Michel P; Department of Neurosurgery, Brussels Saint-Luc University Hospital, Brussels, Belgium.
Schaller K; Division of Neurosurgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
Stienen MN; Department of Neurosurgery, University Hospital Zurich and Clinical Neuroscience Center, University of Zurich, Zurich, Switzerland.
Baro V; Academic Neurosurgery, Department of Neuroscience, University of Padova, Padova, Italy.
Cantillano Malone C; Department of Neurosurgery, Pontifical Catholic University of Chile, Sotero del Rio Hospital, Santiago, Chile.
Pociecha J; Epilepsy Department, Neurology Neurophysiology Epilepsy Service Foundation Against Childhood Neurological Diseases, Buenos Aires, Argentina.
Chamorro N; Epilepsy Department, Neurology Neurophysiology Epilepsy Service Foundation Against Childhood Neurological Diseases, Buenos Aires, Argentina.
Muro VL; Epilepsy Department, Neurology Neurophysiology Epilepsy Service Foundation Against Childhood Neurological Diseases, Buenos Aires, Argentina.
von Lehe M; Department of Neurosurgery, Brandenburg Medical School, Neuruppin, Germany.
Vieker S; Department of Neurosurgery, Brandenburg Medical School, Neuruppin, Germany.
Oluigbo C; Department of Neurosurgery, Children's National Medical Center, Washington, District of Columbia, USA.
Gaillard WD; Divisions of Child Neurology and Epilepsy and Neurophysiology, Children's National Medical Center, Washington, District of Columbia, USA.
Al-Khateeb M; Department of Neurosciences, King Faisal Specialist Hospital and Research Center, Alfaisal University, Riyadh, Saudi Arabia.
Al Otaibi F; Department of Neurosciences, King Faisal Specialist Hospital and Research Center, Alfaisal University, Riyadh, Saudi Arabia.
Krayenbühl N; Department of Neurosurgery, University Hospital Zurich and Clinical Neuroscience Center, University of Zurich, Zurich, Switzerland.
Bolton J; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA.
Pearl PL; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA.
Weil AG; Department of Neurosurgery, Saint Justine University Hospital Centre, Montreal, Quebec, Canada.
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Źródło :
Epilepsia [Epilepsia] 2021 Nov; Vol. 62 (11), pp. 2707-2718. Date of Electronic Publication: 2021 Sep 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
F-FET-PET-guided gross total resection improves overall survival in patients with WHO grade III/IV glioma: moving towards a multimodal imaging-guided resection.
Autorzy :
Ort J; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany. .; NAILA-Neurosurgical Artificial Intelligence Laboratory Aachen, Aachen, Germany. .; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany. .
Hamou HA; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Kernbach JM; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; NAILA-Neurosurgical Artificial Intelligence Laboratory Aachen, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Hakvoort K; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; NAILA-Neurosurgical Artificial Intelligence Laboratory Aachen, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Blume C; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Lohmann P; Institute of Neuroscience and Medicine (INM-3, INM-4), Research Center Juelich, Juelich, Germany.; Department of Stereotaxy and Functional Neurosurgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Galldiks N; Institute of Neuroscience and Medicine (INM-3, INM-4), Research Center Juelich, Juelich, Germany.; Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Heiland DH; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, Freiburg University, Freiburg, Germany.
Mottaghy FM; Department of Nuclear Medicine, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; JARA-Juelich Aachen Research Alliance, Juelich, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Clusmann H; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Neuloh G; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Langen KJ; Institute of Neuroscience and Medicine (INM-3, INM-4), Research Center Juelich, Juelich, Germany.; Department of Nuclear Medicine, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; JARA-Juelich Aachen Research Alliance, Juelich, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Delev D; Department of Neurosurgery, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.; NAILA-Neurosurgical Artificial Intelligence Laboratory Aachen, Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2021 Oct; Vol. 155 (1), pp. 71-80. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Choroidal artery ischemic events after temporal lobe epilepsy surgery: clinical outcome, quality of life, and surgical pitfalls.
Autorzy :
Delev D; 1Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany.
Hakvoort K; 1Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany.
Krüger MT; 2Department of Neurosurgery, Cantonal Hospital St. Gallen, Switzerland; and.; 3Department of Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Blume C; 1Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany.
Clusmann H; 1Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany.
Neuloh G; 1Department of Neurosurgery, RWTH University Aachen, University Medical Center, Aachen, Germany.
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Źródło :
Journal of neurosurgery [J Neurosurg] 2021 Aug 27, pp. 1-7. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Pramipexole and tolcapone alleviate thermal and mechanical nociception in naive rats.
Autorzy :
Mihaylova A; Medical University of Plovdiv, Plovdiv, Bulgaria.
Kostadinov I; Medical University of Plovdiv, Plovdiv, Bulgaria.
Doncheva N; Medical University of Plovdiv, Plovdiv, Bulgaria.
Delev D; Medical University of Plovdiv, Plovdiv, Bulgaria.
Zlatanova H; Medical University of Plovdiv, Plovdiv, Bulgaria.
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Źródło :
Folia medica [Folia Med (Plovdiv)] 2021 Jun 30; Vol. 63 (3), pp. 377-384.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Mapping of Metabolic Heterogeneity of Glioma Using MR-Spectroscopy.
Autorzy :
Franco P; Department of Neurosurgery, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Huebschle I; Department of Neurosurgery, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Simon-Gabriel CP; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Department of Radiology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Dacca K; Department of Neurosurgery, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Schnell O; Department of Neurosurgery, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Beck J; Department of Neurosurgery, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Mast H; Department of Neuroradiology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Urbach H; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Department of Neuroradiology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Wuertemberger U; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Department of Neuroradiology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Prinz M; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, 79106 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Hosp JA; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Department of Neurology and Neuroscience, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Delev D; Department of Neurosurgery, RWTH University of Aachen, 52074 Aachen, Germany.
Mader I; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Department of Neuroradiology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Specialist Centre for Radiology, Schoen Clinic, 83569 Vogtareuth, Germany.
Heiland DH; Department of Neurosurgery, Medical Center-University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2021 May 17; Vol. 13 (10). Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats.
Autorzy :
Mihaylova A; Department of Pharmacology and Drug Toxicology, Faculty of Pharmacy, Medical University of Plovdiv, Bulgaria.
Doncheva N; Department of Pharmacology and Drug Toxicology, Faculty of Pharmacy, Medical University of Plovdiv, Bulgaria.
Zlatanova H; Department of Pharmacology and Clinical Pharmacology, Medical Faculty, Medical University of Plovdiv, Bulgaria.
Delev D; Department of Pharmacology and Clinical Pharmacology, Medical Faculty, Medical University of Plovdiv, Bulgaria.
Ivanovska M; Department of Microbiology and Immunology, Research Institute (RIMU), Faculty of Pharmacy, Medical University of Plovdiv, Bulgaria.
Koeva Y; Department of Anatomy, Histology and Embryology, Medical Faculty, Medical University of Plovdiv, Bulgaria.
Murdjeva M; Department of Microbiology and Immunology, Research Institute (RIMU), Faculty of Pharmacy, Medical University of Plovdiv, Bulgaria.
Kostadinov I; Department of Pharmacology and Clinical Pharmacology, Medical Faculty, Medical University of Plovdiv, Bulgaria.
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Źródło :
Iranian journal of basic medical sciences [Iran J Basic Med Sci] 2021 May; Vol. 24 (5), pp. 577-585.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Hemispherectomy Outcome Prediction Scale: Development and validation of a seizure freedom prediction tool.
Autorzy :
Weil AG; Department of Neurosurgery, Saint Justine University Hospital Centre, Montreal, Quebec, Canada.
Lewis EC; Neurology Centre of Toronto, Toronto, Ontario, Canada.
Ibrahim GM; Division of Pediatric Neurosurgery, Sick Kids Toronto, University of Toronto, Toronto, Ontario, Canada.
Kola O; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Tseng CH; Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Zhou X; Department of Biostatistics, Fielding School of Public Health at, University of California, Los Angeles, Los Angeles, CA, USA.
Lin KM; Department of Functional Neurosurgery, Xiamen Humanity Hospital, Xiamen, China.
Cai LX; Pediatric Epilepsy Center, Peking University First Hospital, Beijing, China.
Liu QZ; Pediatric Epilepsy Center, Peking University First Hospital, Beijing, China.
Lin JL; Department of Epilepsy Center, Yuquan Hospital, Tsinghua University, Beijing, China.
Zhou WJ; Department of Epilepsy Center, Yuquan Hospital, Tsinghua University, Beijing, China.
Mathern GW; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Smyth MD; Department of Neurological Surgery, St. Louis Children's Hospital, St. Louis, Missouri, USA.
O'Neill BR; Department of Neurosurgery, Children's Hospital Colorado, Aurora, Colorado, USA.
Dudley R; Division of Neurosurgery, Department of Pediatric Surgery, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Ragheb J; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, Florida, USA.
Bhatia S; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, Florida, USA.
Delev D; Department of Neurosurgery, University Medical Center Freiburg and Medical Faculty, University of Freiburg, Freiburg, Germany.
Ramantani G; Department of Neurosurgery, University Medical Center Freiburg and Medical Faculty, University of Freiburg, Freiburg, Germany.; Department of Neuropediatrics, University Children's Hospital Zurich, Zurich, Switzerland.
Zentner J; Department of Neurosurgery, University Medical Center Freiburg and Medical Faculty, University of Freiburg, Freiburg, Germany.
Ojemann J; Department of Neurosurgery, Seattle Children's Hospital, Seattle, Washington, USA.
Wang AC; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Dorfer C; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Feucht M; Department of Pediatrics, Medical University of Vienna, Vienna, Austria.
Czech T; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Bollo RJ; Division of Pediatric Neurosurgery, Department of Neurosurgery, Primary Children's Hospital, Salt Lake City, Utah, USA.
Issabekov G; Department of Functional Neurosurgery, Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zhu H; Department of Functional Neurosurgery, Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Connelly M; Department of Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.
Steinbok P; Department of Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.
Zhang JG; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang K; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hidalgo ET; Division of Pediatric Neurosurgery, Department of Surgery, Hassenfeld Children's Hospital, NYU Langone Health, New York, New York, USA.
Weiner HL; Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Wong-Kisiel L; Division of Child Neurology and Epilepsy, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Lapalme-Remis S; Division of Neurology, Department of Medicine, University of Montreal Hospital Centre, Montreal, Quebec, Canada.
Tripathi M; Department of Neurology, All India Institute of Medical Sciences and National Brain Research Center, New Delhi, India.
Sarat Chandra P; Department of Neurosurgery (Center of Excellence for Epilepsy & Magnetoencephalography), All India Institute of Medical Sciences and National Brain Research Center, New Delhi, India.
Hader W; Division of Neurosurgery, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Wang FP; Department of Functional Neurosurgery, Xiamen Humanity Hospital, Xiamen, China.
Yao Y; Division of Epilepsy Surgery, Shenzhen Children's Hospital, Shenzhen, China.
Olivier Champagne P; Department of Neurosurgery, Saint Justine University Hospital Centre, Montreal, Quebec, Canada.
Guo Q; Department of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou Shi, China.
Li SC; Department of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou Shi, China.
Budke M; Department of Neurosurgery, Niño Jesus University Children's Hospital, Madrid, Spain.
Pérez-Jiménez MA; Department of Neurophysiology, Niño Jesus University Children's Hospital, Madrid, Spain.
Raftapoulos C; Department of Neurosurgery, Brussels Saint-Luc University Hospital, Brussels, Belgium.
Finet P; Department of Neurosurgery, Brussels Saint-Luc University Hospital, Brussels, Belgium.
Michel P; Department of Neurosurgery, Brussels Saint-Luc University Hospital, Brussels, Belgium.
Schaller K; Division of Neurosurgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
Stienen MN; Department of Neurosurgery, Zurich University Hospital and Clinical Neuroscience Center, University of Zurich, Zurich, Switzerland.
Baro V; Academic Neurosurgery, Department of Neurosciences, University of Padua, Padua, Italy.
Cantillano Malone C; Department of Neurosurgery, Pontifical Catholic University of Chile, Sotero del Rio Hospital, Santiago, Chile.
Pociecha J; Epilepsy Department, Fleni Epilepsy Neurology and Neurophysiology Service, Buenos Aires, Argentina.
Chamorro N; Epilepsy Department, Fleni Epilepsy Neurology and Neurophysiology Service, Buenos Aires, Argentina.
Muro VL; Epilepsy Department, Fleni Epilepsy Neurology and Neurophysiology Service, Buenos Aires, Argentina.
von Lehe M; Department of Neurosurgery, University Hospital Bochum, Bochum, Germany.; Department of Neurosurgery, Brandenburg Medical School, Neuruppin, Germany.
Vieker S; Department of Neurosurgery, University Hospital Bochum, Bochum, Germany.; Department of Neurosurgery, Brandenburg Medical School, Neuruppin, Germany.
Oluigbo C; Department of Neurosurgery, Children's National Medical Center, Washington, District of Columbia, USA.
Gaillard WD; Divisions of Child Neurology and Epilepsy and Neurophysiology, Children's National Medical Center, Washington, District of Columbia, USA.
Al Khateeb M; Department of Neurosciences, King Faisal Specialist Hospital and Research Center, Alfaisal University, Riyadh, Saudi Arabia.
Al Otaibi F; Department of Neurosciences, King Faisal Specialist Hospital and Research Center, Alfaisal University, Riyadh, Saudi Arabia.
Krayenbühl N; Department of Neurosurgery, Zurich University Hospital and Clinical Neuroscience Center, University of Zurich, Zurich, Switzerland.
Bolton J; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA.
Pearl PL; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts, USA.
Fallah A; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
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Źródło :
Epilepsia [Epilepsia] 2021 May; Vol. 62 (5), pp. 1064-1073. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article; Multicenter Study; Validation Study
MeSH Terms :
Hemispherectomy*
Treatment Outcome*
Drug Resistant Epilepsy/*surgery
Age of Onset ; Child ; Child, Preschool ; Cohort Studies ; Drug Resistant Epilepsy/pathology ; Drug Resistant Epilepsy/physiopathology ; Female ; Humans ; Infant ; Logistic Models ; Male ; Prognosis ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Surgery for IDH1/2 wild-type glioma invading the corpus callosum.
Autorzy :
Franco P; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany. .; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany. .
Delev D; Department of Neurosurgery, University of Aachen, Aachen, NRW, Germany.
Cipriani D; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Neidert N; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Kellner E; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.; Department of Radiology, Medical Centre - University of Freiburg, Freiburg, BW, Germany.
Masalha W; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Mercas B; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Mader I; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.; Specialist Centre for Radiology, Schoen Clinic, Vogtareuth, BY, Germany.
Reinacher P; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.; Department of Neurosurgery, Division Stereotactic and Functional Neurosurgery, Medical Center- University of Freiburg, Freiburg, BW, Germany.
Weyerbrock A; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Fung C; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Beck J; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Heiland DH; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
Schnell O; Department of Neurosurgery, Medical Center - University of Freiburg, Breisacher Straße 64, 79106, Freiburg, BW, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, BW, Germany.
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Źródło :
Acta neurochirurgica [Acta Neurochir (Wien)] 2021 Apr; Vol. 163 (4), pp. 937-945. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*surgery
Corpus Callosum/*pathology
Glioma/*surgery
Postoperative Complications/*epidemiology
Adult ; Aged ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Corpus Callosum/surgery ; Female ; Glioma/genetics ; Glioma/pathology ; Humans ; Isocitrate Dehydrogenase/genetics ; Karnofsky Performance Status ; Male ; Middle Aged ; Neurosurgical Procedures/adverse effects ; Neurosurgical Procedures/methods ; Tumor Burden
Czasopismo naukowe
Tytuł :
Metabolic alterations in meningioma reflect the clinical course.
Autorzy :
Masalha W; Department of Neurosurgery, University Medical Center Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany. .; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany. .
Daka K; Department of Neurosurgery, University Medical Center Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Woerner J; Institute of Physical Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg im Breisgau, Germany.
Pompe N; Institute of Physical Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg im Breisgau, Germany.
Weber S; Institute of Physical Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg im Breisgau, Germany.
Delev D; Department of Neurosurgery, RWTH University, Aachen, Germany.
Krüger MT; Department of Neurosurgery, Cantonal Hospital St.Gallen, st. gallen, Switzerland.
Schnell O; Department of Neurosurgery, University Medical Center Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Beck J; Department of Neurosurgery, University Medical Center Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Heiland DH; Department of Neurosurgery, University Medical Center Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Grauvogel J; Department of Neurosurgery, University Medical Center Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
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Źródło :
BMC cancer [BMC Cancer] 2021 Mar 01; Vol. 21 (1), pp. 211. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Biomarkers, Tumor/*analysis
Meningeal Neoplasms/*metabolism
Meningioma/*metabolism
Aged ; Algorithms ; Choline/metabolism ; Cluster Analysis ; Disease Progression ; Female ; Glycine/metabolism ; Humans ; Male ; Meningeal Neoplasms/chemistry ; Meningeal Neoplasms/mortality ; Meningioma/chemistry ; Meningioma/mortality ; Middle Aged ; Neoplasm Grading ; Nuclear Magnetic Resonance, Biomolecular ; Progression-Free Survival ; Serine/metabolism ; Treatment Outcome ; Tryptophan/metabolism
Czasopismo naukowe
Tytuł :
Multi-scale image analysis and prediction of visual field defects after selective amygdalohippocampectomy.
Autorzy :
David B; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Eberle J; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.; Clinic for Neurology and Palliative Medicine, Municipal Hospital Köln-Merheim, Cologne, Germany.
Delev D; Department of Neurosurgery, RWTH University Aachen, Aachen, Germany.
Gaubatz J; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Prillwitz CC; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Wagner J; Department of Neurology, University of Ulm and Universitäts- and Rehabilitationskliniken Ulm, Ulm, Germany.
Schoene-Bake JC; Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany.
Luechters G; Center for Development Research, University of Bonn, Bonn, Germany.
Radbruch A; Department of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Wabbels B; Department of Ophthalmology, University Hospital Bonn, Bonn, Germany.
Schramm J; Medical Faculty, University Hospital Bonn, Bonn, Germany.
Weber B; Institute of Experimental Epileptology and Cognition Research, University Hospital Bonn, Bonn, Germany.
Surges R; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Elger CE; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
Rüber T; Department of Epileptology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany. .; Department of Neurology, Epilepsy Center Frankfurt Rhine-Main, Goethe University Frankfurt, Frankfurt am Main, Germany. .; Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, Frankfurt am Main, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jan 14; Vol. 11 (1), pp. 1444. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epilepsy, Temporal Lobe*/diagnostic imaging
Epilepsy, Temporal Lobe*/physiopathology
Epilepsy, Temporal Lobe*/surgery
Postoperative Complications*/diagnostic imaging
Postoperative Complications*/physiopathology
Temporal Lobe*/diagnostic imaging
Temporal Lobe*/surgery
Vision Disorders*/diagnostic imaging
Vision Disorders*/etiology
Vision Disorders*/physiopathology
Neurosurgical Procedures/*adverse effects
Adult ; Diffusion Tensor Imaging ; Female ; Humans ; Male ; Middle Aged ; Visual Field Tests
Czasopismo naukowe
Tytuł :
Navigated Deep Brain Stimulation Surgery: Evaluating the Combined Use of a Frame-Based Stereotactic System and a Navigation System.
Autorzy :
Krüger MT; Department of Stereotactic and Functional Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Cantonal Hospital, St. Gallen, Switzerland.
Várkuti B; Brainlab AG, Munich, Germany.
Achinger J; Brainlab AG, Munich, Germany.
Coenen VA; Department of Stereotactic and Functional Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Basics in Neuromodulation, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Deep Brain Stimulation, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Prokop T; Department of Stereotactic and Functional Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Delev D; Department of Neurosurgery, University Medical Center Aachen, Aachen, Germany.
Blass BI; Department of Stereotactic and Functional Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Piroth T; Department of Stereotactic and Functional Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland.
Reinacher PC; Department of Stereotactic and Functional Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany, .; Fraunhofer Institute for Laser Technology, Aachen, Germany, .
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Źródło :
Stereotactic and functional neurosurgery [Stereotact Funct Neurosurg] 2021; Vol. 99 (1), pp. 48-54. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Deep Brain Stimulation/*standards
Neuronavigation/*standards
Neurosurgeons/*standards
Stereotaxic Techniques/*standards
Deep Brain Stimulation/methods ; Electrodes, Implanted/standards ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Imaging, Three-Dimensional/standards ; Male ; Microelectrodes/standards ; Movement Disorders/diagnostic imaging ; Movement Disorders/surgery ; Neuronavigation/methods ; Neurosurgical Procedures/methods ; Neurosurgical Procedures/standards ; Phantoms, Imaging/standards
Czasopismo naukowe
Tytuł :
Asymmetric tumor-related alterations of network-specific intrinsic functional connectivity in glioma patients.
Autorzy :
Jütten K; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Mainz V; Institute of Medical Psychology and Medical Sociology, RWTH Aachen University, Aachen, Germany.
Delev D; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Gauggel S; Institute of Medical Psychology and Medical Sociology, RWTH Aachen University, Aachen, Germany.
Binkofski F; Division of Clinical Cognitive Sciences, RWTH Aachen University, Aachen, Germany.
Wiesmann M; Department of Diagnostic and Interventional Neuroradiology, RWTH Aachen University, Aachen, Germany.
Clusmann H; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Na CH; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
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Źródło :
Human brain mapping [Hum Brain Mapp] 2020 Nov; Vol. 41 (16), pp. 4549-4561. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Connectome*
Magnetic Resonance Imaging*
Brain Neoplasms/*physiopathology
Cerebral Cortex/*physiopathology
Cognitive Dysfunction/*physiopathology
Default Mode Network/*physiopathology
Glioma/*physiopathology
Adult ; Aged ; Brain Neoplasms/complications ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/pathology ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/etiology ; Default Mode Network/diagnostic imaging ; Default Mode Network/pathology ; Female ; Glioma/complications ; Glioma/diagnostic imaging ; Glioma/pathology ; Humans ; Male ; Middle Aged ; Nerve Net ; Neuropsychological Tests
Czasopismo naukowe
Tytuł :
Quality of life in elderly patients after surgery for drug-resistant epilepsy - The impact of seizure outcome, neurological deficits and anxiety.
Autorzy :
Delev D; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany. Electronic address: .
Hakvoort K; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Grote A; Clinic for Neurosurgery, Evangelic Hospital of Bethel, Bielefeld, Germany.
Neuloh G; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Clusmann H; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
von Lehe M; Department of Neurosurgery, Ruppiner Kliniken, Brandenburg Medical School, Neuruppin, Germany; Medical Faculty, University of Bonn Medical Center, Bonn, Germany.
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Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2020 Nov; Vol. 112, pp. 107410. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Epilepsy*/surgery
Pharmaceutical Preparations*
Aged ; Anxiety/etiology ; Humans ; Quality of Life ; Seizures ; Surveys and Questionnaires
Czasopismo naukowe
Tytuł :
Characterization of longitudinal transformation of T2-hyperintensity in oligodendroglioma.
Autorzy :
Heiland DH; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany. .; Medical Faculty, Freiburg University, Freiburg, Germany. .
Ohle R; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Cipriani D; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Franco P; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Delev D; Department of Neurosurgery, University of Aachen, Aachen, Germany.
Behriger SP; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Kellner E; Medical Physics, Department of Radiology, Medical Centre - University of Freiburg, Freiburg, Germany.
Petrova G; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Neidert N; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Mader I; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, Vogtareuth, Germany.
Nuñez MF; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Urbach H; Medical Faculty, Freiburg University, Freiburg, Germany.; Department of Neuroradiology, Medical Center - University of Freiburg, Freiburg, Germany.
Sankowski R; Medical Faculty, Freiburg University, Freiburg, Germany.; Institute of Neuropathology, Medical Center - University of Freiburg, Freiburg, Germany.; Berta-Ottenstein-Programme for Clinician Scientists Medical Center, University of Freiburg, Freiburg, Germany.
Beck J; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Schnell O; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
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Źródło :
BMC cancer [BMC Cancer] 2020 Aug 27; Vol. 20 (1), pp. 818. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Astrocytoma/*diagnostic imaging
Brain Neoplasms/*diagnostic imaging
Magnetic Resonance Imaging/*methods
Neoplasm Recurrence, Local/*diagnostic imaging
Oligodendroglioma/*diagnostic imaging
Adult ; Aged ; Aged, 80 and over ; Astrocytoma/genetics ; Brain Neoplasms/genetics ; Chromosome Deletion ; Chromosomes, Human, Pair 1/genetics ; Chromosomes, Human, Pair 19/genetics ; Female ; Follow-Up Studies ; Humans ; Isocitrate Dehydrogenase/genetics ; Longitudinal Studies ; Male ; Middle Aged ; Mutation ; Neoplasm Recurrence, Local/genetics ; Neoplasm Staging ; Oligodendroglioma/genetics ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Surgery for temporal lobe epilepsy in the elderly: Improving quality of life despite cognitive impairment.
Autorzy :
Delev D; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany. Electronic address: .
Taube J; Dept. of Epileptology, University of Bonn Medical Center, Bonn, Germany.
Helmstaedter C; Dept. of Epileptology, University of Bonn Medical Center, Bonn, Germany.
Hakvoort K; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Grote A; Clinic for Neurosurgery, Evangelic Hospital of Bethel, Bielefeld, Germany.
Clusmann H; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Lehe MV; Department of Neurosurgery, Ruppiner Kliniken, Brandenburg Medical School, Neuruppin, Germany; Medical Faculty, University of Bonn Medical Center, Bonn, Germany.
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Źródło :
Seizure [Seizure] 2020 Jul; Vol. 79, pp. 112-119. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Cognitive Dysfunction*/etiology
Neurosurgical Procedures*/adverse effects
Outcome Assessment, Health Care*
Quality of Life*
Drug Resistant Epilepsy/*surgery
Epilepsy, Temporal Lobe/*surgery
Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Long-term epilepsy-associated tumors: transcriptional signatures reflect clinical course.
Autorzy :
Delev D; Department of Neurosurgery, Medical Center, Freiburg, Germany. daniel.delev@gmail.com.; Department of Neurosurgery, RWTH University Aachen, Aachen, Germany. daniel.delev@gmail.com.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany. daniel.delev@gmail.com.; Medical Faculty, Freiburg University, Freiburg, Germany. daniel.delev@gmail.com.
Daka K; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Heynckes S; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Gaebelein A; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Franco P; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Pfeifer D; Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Prinz M; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; Center for NeuroModulation (NeuroModul), University of Freiburg, Freiburg, Germany.; Institute of Neuropathology, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Schnell O; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Urbach H; Department of Neuroradiology, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Mader I; Department of Neuroradiology, Medical Center, University of Freiburg, Freiburg, Germany.; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, Vogtareuth, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Beck J; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Grote A; Clinic for Neurosurgery, Evangelic Hospital of Bethel, Bielefeld, Germany.
Becker AJ; Section for Translational Epilepsy Research, Department of Neuropathology, University of Bonn Medical Center, Bonn, Germany.
Heiland DH; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
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Źródło :
Scientific reports [Sci Rep] 2020 Jan 09; Vol. 10 (1), pp. 96. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Biomarkers, Tumor/*genetics
Brain Neoplasms/*etiology
Epilepsy/*complications
Neoplasm Recurrence, Local/*etiology
Adolescent ; Adult ; Aged ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Child ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/metabolism ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Young Adult
Czasopismo naukowe
Tytuł :
Resection of recurrent glioblastoma multiforme in elderly patients: a pseudo-randomized analysis revealed clinical benefit.
Autorzy :
Fariña Nuñez MT; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany. .; Medical Faculty, University of Freiburg, Freiburg, Germany. .
Franco P; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Cipriani D; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Neidert N; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Behringer SP; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Mader I; Department of Neuroradiology, Medical Center, University of Freiburg, Freiburg, Germany.; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, Vogtareuth, Germany.
Delev D; Department of Neurosurgery, University of Aachen, Aachen, Germany.
Fung C; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Beck J; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Sankowski R; Institute of Neuropathology, Medical Center, University of Freiburg, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Nicolay NH; Medical Faculty, University of Freiburg, Freiburg, Germany.; Department of Radiation Oncology, Medical Center, University of Freiburg, Freiburg, Germany.
Heiland DH; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
Schnell O; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Medical Faculty, University of Freiburg, Freiburg, Germany.
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2020 Jan; Vol. 146 (2), pp. 381-387. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Quality of Life*
Brain Neoplasms/*mortality
Glioblastoma/*mortality
Neoplasm Recurrence, Local/*mortality
Neurosurgical Procedures/*mortality
Reoperation/*mortality
Aged ; Brain Neoplasms/pathology ; Brain Neoplasms/surgery ; Female ; Follow-Up Studies ; Glioblastoma/pathology ; Glioblastoma/surgery ; Humans ; Male ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/surgery ; Prognosis ; Reoperation/methods ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Survival and Prognostic Predictors of Anaplastic Meningiomas.
Autorzy :
Masalha W; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address: .
Heiland DH; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Delev D; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Fennell JT; Department of Radiation Oncology, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
Franco P; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Scheiwe C; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Mercas BI; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Mader I; Department of Neuroradiology, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Schnell O; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Grauvogel J; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
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Źródło :
World neurosurgery [World Neurosurg] 2019 Nov; Vol. 131, pp. e321-e328. Date of Electronic Publication: 2019 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Neurosurgical Procedures*
Meningeal Neoplasms/*therapy
Meningioma/*therapy
Neoplasm Recurrence, Local/*epidemiology
Aged ; Anaplasia ; Combined Modality Therapy ; Female ; Humans ; Male ; Meningeal Neoplasms/pathology ; Meningioma/pathology ; Middle Aged ; Neoplasm Grading ; Prognosis ; Progression-Free Survival ; Proportional Hazards Models ; Radiotherapy, Adjuvant ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma.
Autorzy :
Wurm J; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Behringer SP; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Ravi VM; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Joseph K; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Neidert N; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Maier JP; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Doria-Medina R; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Follo M; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .; Department of Medicine I, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .
Delev D; Department of Neurosurgery, University of Aachen, 79106 Aachen, Germany. .
Pfeifer D; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .; Department of Medicine I, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .
Beck J; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Sankowski R; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. .; Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. .
Schnell O; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
Heiland DH; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106 Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106 Freiburg, Germany. .
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Źródło :
Cancers [Cancers (Basel)] 2019 Sep 26; Vol. 11 (10). Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Simultaneous Frame-assisted Stereotactic Placement of Subdural Grid Electrodes and Intracerebral Depth Electrodes.
Autorzy :
Reinacher PC; Department of Stereotactic and Functional Neurosurgery, Freiburg University Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Altenmüller DM; Medical Faculty, Freiburg University, Freiburg, Germany.; Department of Epileptology, Freiburg University Medical Center, Freiburg, Germany.
Krüger MT; Medical Faculty, Freiburg University, Freiburg, Germany.; Department of Neurosurgery, Freiburg University Medical Center, Freiburg, Germany.
Schulze-Bonhage A; Medical Faculty, Freiburg University, Freiburg, Germany.; Department of Epileptology, Freiburg University Medical Center, Freiburg, Germany.
Urbach H; Medical Faculty, Freiburg University, Freiburg, Germany.; Department of Neuroradiology, Freiburg University Medical Center, Freiburg, Germany.
Trippel M; Department of Stereotactic and Functional Neurosurgery, Freiburg University Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Coenen VA; Department of Stereotactic and Functional Neurosurgery, Freiburg University Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Delev D; Medical Faculty, Freiburg University, Freiburg, Germany.; Department of Neurosurgery, Freiburg University Medical Center, Freiburg, Germany.
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Źródło :
Journal of neurological surgery. Part A, Central European neurosurgery [J Neurol Surg A Cent Eur Neurosurg] 2019 Sep; Vol. 80 (5), pp. 353-358. Date of Electronic Publication: 2019 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Electrodes, Implanted*
Epilepsy, Temporal Lobe/*surgery
Subdural Space/*surgery
Adolescent ; Adult ; Electroencephalography ; Female ; Humans ; Imaging, Three-Dimensional ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Stereotaxic Techniques ; Young Adult
Czasopismo naukowe
Tytuł :
Human organotypic brain slice culture: a novel framework for environmental research in neuro-oncology.
Autorzy :
Ravi VM; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany .; Neuroelectronic Systems, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Joseph K; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Wurm J; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Behringer S; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Garrelfs N; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
d'Errico P; Department of Neurology, Medical Centre, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Naseri Y; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Franco P; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Meyer-Luehmann M; Department of Neurology, Medical Centre, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Sankowski R; Institute of Neuropathology, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Shah MJ; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Mader I; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, Vogtareuth, Germany.
Delev D; Department of Neurosurgery, University of Aachen, Aachen, Germany.
Follo M; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.; Department of Medicine I, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.
Beck J; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Schnell O; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Hofmann UG; Neuroelectronic Systems, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Heiland DH; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany .; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
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Źródło :
Life science alliance [Life Sci Alliance] 2019 Jun 27; Vol. 2 (4). Date of Electronic Publication: 2019 Jun 27 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms*/drug therapy
Brain Neoplasms*/immunology
Brain Neoplasms*/metabolism
Brain Neoplasms*/pathology
Glioblastoma*/drug therapy
Glioblastoma*/immunology
Glioblastoma*/metabolism
Glioblastoma*/pathology
Tissue Culture Techniques/*methods
Adult ; Aged ; Aged, 80 and over ; Astrocytes/metabolism ; Brain/cytology ; Brain/metabolism ; Brain/surgery ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Infant ; Male ; Middle Aged ; Models, Biological ; Nerve Tissue/cytology ; Nerve Tissue/metabolism ; Nerve Tissue/surgery ; Temozolomide/pharmacology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma.
Autorzy :
Henrik Heiland D; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany. .; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany. .; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany. .
Ravi VM; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.; Neuroelectronic Systems, Medical Center, University of Freiburg, 79106, Freiburg, Germany.
Behringer SP; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Frenking JH; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Wurm J; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Joseph K; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.; Neuroelectronic Systems, Medical Center, University of Freiburg, 79106, Freiburg, Germany.
Garrelfs NWC; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Strähle J; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Heynckes S; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Grauvogel J; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Franco P; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Mader I; Department of Neuroradiology, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, 83569, Vogtareuth, Germany.
Schneider M; Department of Neurosurgery, University of Bonn, 53113, Bonn, Germany.
Potthoff AL; Department of Neurosurgery, University of Bonn, 53113, Bonn, Germany.
Delev D; Department of Neurosurgery, University of Aachen, 52062, Aachen, Germany.
Hofmann UG; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.; Neuroelectronic Systems, Medical Center, University of Freiburg, 79106, Freiburg, Germany.
Fung C; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Beck J; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
Sankowski R; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.; Institute of Neuropathology, Medical Center, University of Freiburg, 79106, Freiburg, Germany.
Prinz M; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.; Institute of Neuropathology, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104, Freiburg, Germany.; Center for NeuroModulation (NeuroModul), University of Freiburg, 79106, Freiburg, Germany.
Schnell O; Translational NeuroOncology Research Group, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Medicine, Freiburg University, 79106, Freiburg, Germany.
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Źródło :
Nature communications [Nat Commun] 2019 Jun 11; Vol. 10 (1), pp. 2541. Date of Electronic Publication: 2019 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Cytokines/*metabolism
Glioblastoma/*immunology
Microglia/*metabolism
Astrocytes/cytology ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Gene Expression Profiling ; Humans ; Inflammation Mediators ; Janus Kinases/metabolism ; Microglia/cytology ; Phenotype ; STAT Transcription Factors/metabolism ; Sequence Analysis, RNA ; Signal Transduction ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Catechol-o-methyltransferase inhibitor tolcapone improves learning and memory in naïve but not in haloperidol challenged rats.
Autorzy :
Mihaylova A; Department of Pharmacology and Drug Toxicology, Faculty of Pharmacy, Medical University Plovdiv, 15A Vassil Aprilov Blvd., Plovdiv 4002, Bulgaria.
Zlatanova H; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 15A Vassil Aprilov Blvd., Plovdiv 4002, Bulgaria.
Doncheva N; Department of Pharmacology and Drug Toxicology, Faculty of Pharmacy, Medical University Plovdiv, 15A Vassil Aprilov Blvd., Plovdiv 4002, Bulgaria.
Delev D; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 15A Vassil Aprilov Blvd., Plovdiv 4002, Bulgaria.
Kostadinov I; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 15A Vassil Aprilov Blvd., Plovdiv 4002, Bulgaria.
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Źródło :
Iranian journal of basic medical sciences [Iran J Basic Med Sci] 2019 Jun; Vol. 22 (6), pp. 695-702.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Biological Screening of Novel Structural Analog of Celecoxib as Potential Anti-Inflammatory and Analgesic Agent.
Autorzy :
Zlatanova H; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 4002 Plovdiv, Bulgaria. .
Vladimirova S; Department of Organic Synthesis and Fuels, Faculty of Chemical Technologies, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria. .
Kostadinov I; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 4002 Plovdiv, Bulgaria. .
Delev D; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 4002 Plovdiv, Bulgaria. .
Deneva T; Medical University Plovdiv, 4002 Plovdiv, Bulgaria. .
Kostadinova I; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University Plovdiv, 4002 Plovdiv, Bulgaria. .
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Źródło :
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2019 Apr 05; Vol. 55 (4). Date of Electronic Publication: 2019 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Evaluation, Preclinical*
Analgesics/*chemistry
Analgesics/*pharmacology
Anti-Inflammatory Agents, Non-Steroidal/*chemistry
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Celecoxib/*analogs & derivatives
Celecoxib/*pharmacology
Indoles/*chemistry
Indoles/*pharmacology
Analgesics/administration & dosage ; Analgesics/adverse effects ; Analysis of Variance ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Behavior, Animal/drug effects ; Blood Platelets/drug effects ; Carrageenan/administration & dosage ; Carrageenan/pharmacology ; Celecoxib/administration & dosage ; Celecoxib/adverse effects ; Edema/chemically induced ; Edema/drug therapy ; Erythrocytes/drug effects ; Hemoglobins/analysis ; Leukocytes/drug effects ; Male ; Models, Animal ; Pain Measurement ; Pyrroles/chemistry ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme.
Autorzy :
Heynckes S; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Daka K; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Franco P; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Gaebelein A; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Frenking JH; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Doria-Medina R; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Mader I; Department of Neuroradiology, Medical Center - University of Freiburg, Freiburg, Germany.; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, Vogtareuth, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Delev D; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Department of Neurosurgery, University of Aachen, Aachen, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Schnell O; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Heiland DH; Department of Neurosurgery, Medical Center University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany. .; Faculty of Medicine, University of Freiburg, Freiburg, Germany. .
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Źródło :
BMC cancer [BMC Cancer] 2019 Feb 01; Vol. 19 (1), pp. 117. Date of Electronic Publication: 2019 Feb 01.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Alkylating/*pharmacology
B7-H1 Antigen/*genetics
Brain Neoplasms/*pathology
Gene Expression Regulation, Neoplastic/*drug effects
Glioblastoma/*pathology
Temozolomide/*pharmacology
B7-H1 Antigen/metabolism ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Gene Expression Profiling ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Humans ; Immunohistochemistry ; Interferon-gamma/pharmacology ; Phosphorylation/drug effects ; STAT Transcription Factors/genetics ; STAT Transcription Factors/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Surgical management of lower-grade glioma in the spotlight of the 2016 WHO classification system.
Autorzy :
Delev D; Department of Neurosurgery, Medical Center, Freiburg, Germany. delev..; Medical Faculty, Freiburg University, Freiburg, Germany. delev..
Heiland DH; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Franco P; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Reinacher P; Department of Stereotactic and Functional Neurosurgery, Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Mader I; Department of Neuroradiology, Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Staszewski O; Institute of Neuropathology, Freiburg University Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Lassmann S; Institute of Pathology, University of Freiburg, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
Grau S; Department of Neurosurgery, University Hospital Cologne, Cologne, Germany.
Schnell O; Department of Neurosurgery, Medical Center, Freiburg, Germany.; Medical Faculty, Freiburg University, Freiburg, Germany.
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2019 Jan; Vol. 141 (1), pp. 223-233. Date of Electronic Publication: 2018 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*classification
Brain Neoplasms/*surgery
Glioma/*classification
Glioma/*surgery
Adolescent ; Adult ; Brain Neoplasms/genetics ; Child ; Chromosome Deletion ; Chromosomes, Human, Pair 1/genetics ; Chromosomes, Human, Pair 19/genetics ; Glioma/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Kaplan-Meier Estimate ; Middle Aged ; Mutation ; Retrospective Studies ; Treatment Outcome ; World Health Organization ; Young Adult
Czasopismo naukowe
Tytuł :
Surgical Treatment of Extratemporal Epilepsy: Results and Prognostic Factors.
Autorzy :
Delev D; Department of Neurosurgery, Medical Center-University of Freiburg, Frieburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Oehl B; Department of Neurosurgery, Medical Center-University of Freiburg, Frieburg, Germany.
Steinhoff BJ; Epilepsy Center Kork, Kehl-Kork, Germany.
Nakagawa J; Department of Neurosurgery, Medical Center-University of Freiburg, Frieburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Scheiwe C; Department of Neurosurgery, Medical Center-University of Freiburg, Frieburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Schulze-Bonhage A; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Freiburg Epilepsy Center, Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.
Zentner J; Department of Neurosurgery, Medical Center-University of Freiburg, Frieburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
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Źródło :
Neurosurgery [Neurosurgery] 2019 Jan 01; Vol. 84 (1), pp. 242-252.
Typ publikacji :
Journal Article
MeSH Terms :
Epilepsy/*pathology
Epilepsy/*surgery
Neurosurgical Procedures/*methods
Adolescent ; Adult ; Aged ; Child ; Epilepsy/complications ; Female ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Prognosis ; Retrospective Studies ; Seizures/etiology ; Seizures/surgery ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Antioxidant Activity of Dry Birch (Betula Pendula) Leaves Extract.
Autorzy :
Penkov D; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria.; High-technological Center of Emergency Medicine, Plovdiv, Bulgaria.
Andonova V; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria.
Delev D; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.
Kostadinov I; Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.
Kassarova M; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria.; High-technological Center of Emergency Medicine, Plovdiv, Bulgaria.
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Źródło :
Folia medica [Folia Med (Plovdiv)] 2018 Dec 01; Vol. 60 (4), pp. 571-579.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*isolation & purification
Antioxidants/*pharmacology
Betula/*chemistry
Animals ; Flavonoids/analysis ; Free Radical Scavengers/isolation & purification ; Free Radical Scavengers/pharmacology ; Free Radicals/blood ; Male ; Medicine, Traditional ; Phytotherapy ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plants, Medicinal/chemistry ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
One decade of glioblastoma multiforme surgery in 342 elderly patients: what have we learned?
Autorzy :
Heiland DH; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany. .; Faculty of Medicine, University of Freiburg, Freiburg, Germany. .
Haaker G; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Watzlawick R; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Delev D; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Masalha W; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Franco P; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Machein M; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Staszewski O; Institute of Neuropathology, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Oelhke O; Radiation Clinic, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nicolay NH; Radiation Clinic, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Schnell O; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2018 Nov; Vol. 140 (2), pp. 385-391. Date of Electronic Publication: 2018 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*surgery
Glioblastoma/*surgery
Aged ; Brain Neoplasms/metabolism ; Brain Neoplasms/mortality ; Combined Modality Therapy ; DNA Methylation ; DNA Modification Methylases/genetics ; DNA Modification Methylases/metabolism ; DNA Repair Enzymes/genetics ; DNA Repair Enzymes/metabolism ; Glioblastoma/metabolism ; Glioblastoma/mortality ; Humans ; Karnofsky Performance Status ; Neurosurgical Procedures ; Retrospective Studies ; Time Factors ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
Correction to: One decade of glioblastoma multiforme surgery in 342 elderly patients: what have we learned?
Autorzy :
Heiland DH; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany. .; Faculty of Medicine, University of Freiburg, Freiburg, Germany. .
Haaker G; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Watzlawick R; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Delev D; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Masalha W; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Franco P; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Machein M; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Staszewski O; Institute of Neuropathology, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Oelhke O; Radiation Clinic, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nicolay NH; Radiation Clinic, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Schnell O; Department of Neurosurgery, Medical Center, University of Freiburg, Breisacher Straße 64, 79106, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2018 Nov; Vol. 140 (2), pp. 393.
Typ publikacji :
Published Erratum
Tytuł :
Cognitive features and surgical outcome of patients with long-term epilepsy-associated tumors (LEATs) within the temporal lobe.
Autorzy :
Vogt VL; Dept. of Epileptology, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany. Electronic address: .
Witt JA; Dept. of Epileptology, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Delev D; Dept. of Neurosurgery, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Grote A; Dept. of Neurosurgery, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
von Lehe M; Dept. of Neurosurgery, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Becker AJ; Dept. of Neuropathology, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Schramm J; Dept. of Neurosurgery, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Elger CE; Dept. of Epileptology, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Helmstaedter C; Dept. of Epileptology, University of Bonn Medical Center, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
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Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2018 Nov; Vol. 88, pp. 25-32. Date of Electronic Publication: 2018 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytoma*/complications
Astrocytoma*/surgery
Brain Neoplasms*/complications
Brain Neoplasms*/surgery
Ganglioglioma*/complications
Ganglioglioma*/surgery
Cognition/*physiology
Epilepsy, Temporal Lobe/*psychology
Epilepsy, Temporal Lobe/*surgery
Adolescent ; Adult ; Analysis of Variance ; Executive Function/physiology ; Female ; Germany ; Hippocampus/surgery ; Humans ; Male ; Middle Aged ; Seizures/psychology ; Seizures/surgery ; Temporal Lobe/surgery ; Young Adult
Czasopismo naukowe
Tytuł :
Neuropsychological outcome after subtemporal versus transsylvian approach for selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy: a randomised prospective clinical trial.
Autorzy :
Vogt VL; Department of Epileptology, University of Bonn-Medical Center, Bonn, Germany.
Delev D; Department of Neurosurgery, University of Bonn-Medical Center, Bonn, Germany.; Department of Neurosurgery, University Medical Center, Freiburg, Germany.
Grote A; Department of Neurosurgery, University of Bonn-Medical Center, Bonn, Germany.
Schramm J; Department of Neurosurgery, University of Bonn-Medical Center, Bonn, Germany.
von Lehe M; Department of Neurosurgery, Knappschaftskrankenhaus Bochum, Bonn, Germany.
Elger CE; Department of Epileptology, University of Bonn-Medical Center, Bonn, Germany.
Witt JA; Department of Epileptology, University of Bonn-Medical Center, Bonn, Germany.
Helmstaedter C; Department of Epileptology, University of Bonn-Medical Center, Bonn, Germany.
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Źródło :
Journal of neurology, neurosurgery, and psychiatry [J Neurol Neurosurg Psychiatry] 2018 Oct; Vol. 89 (10), pp. 1057-1063. Date of Electronic Publication: 2017 Dec 22.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Amygdala/*surgery
Cognition/*physiology
Epilepsy, Temporal Lobe/*surgery
Hippocampus/*surgery
Neurosurgical Procedures/*methods
Temporal Lobe/*surgery
Adult ; Attention/physiology ; Executive Function/physiology ; Female ; Humans ; Male ; Memory/physiology ; Middle Aged ; Neuropsychological Tests ; Postoperative Period ; Prospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme.
Autorzy :
Heiland DH; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany. .; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Gaebelein A; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Börries M; Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University, Freiburg im Breisgau, Germany.; German Cancer Consortium (DKTK), Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Wörner J; Institute of Physical Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg im Breisgau, Germany.
Pompe N; Institute of Physical Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg im Breisgau, Germany.
Franco P; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Heynckes S; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Bartholomae M; Department of Nuclear Medicine, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
hAilín DÓ; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Biology, University of Freiburg, Freiburg im Breisgau, Germany.
Carro MS; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Prinz M; Institute of Neuropathology, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Weber S; Institute of Physical Chemistry, Faculty of Chemistry and Pharmacy, University of Freiburg, Freiburg im Breisgau, Germany.
Mader I; Department of Neuroradiology, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Clinic for Neuropediatrics and Neurorehabilitation, Epilepsy Center for Children and Adolescents, Schön Klinik, Vogtareuth, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Delev D; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Schnell O; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.; Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
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Źródło :
Molecular cancer research : MCR [Mol Cancer Res] 2018 Apr; Vol. 16 (4), pp. 655-668. Date of Electronic Publication: 2018 Jan 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms/*genetics
Creatine/*pharmacology
Gene Expression Profiling/*methods
Glioblastoma/*genetics
Metabolomics/*methods
Signal Transduction/*drug effects
Basic Helix-Loop-Helix Transcription Factors/metabolism ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Cellular Reprogramming ; Creatine/therapeutic use ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Regulatory Networks/drug effects ; Genetic Heterogeneity ; Glioblastoma/drug therapy ; Glioblastoma/metabolism ; Humans ; Sequence Analysis, RNA ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł :
A multimodal concept for invasive diagnostics and surgery based on neuronavigated voxel-based morphometric MRI postprocessing data in previously nonlesional epilepsy.
Autorzy :
Delev D; Departments of1Neurosurgery and.
Quesada CM; 2Epileptology, University of Bonn, University Medical Center, Bonn, Germany.
Grote A; Departments of1Neurosurgery and.
Boström JP; Departments of1Neurosurgery and.
Elger C; 2Epileptology, University of Bonn, University Medical Center, Bonn, Germany.
Vatter H; Departments of1Neurosurgery and.
Surges R; 2Epileptology, University of Bonn, University Medical Center, Bonn, Germany.
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Źródło :
Journal of neurosurgery [J Neurosurg] 2018 Apr; Vol. 128 (4), pp. 1178-1186. Date of Electronic Publication: 2017 Jun 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epilepsy/*diagnostic imaging
Epilepsy/*surgery
Magnetic Resonance Imaging/*methods
Multimodal Imaging/*methods
Neuronavigation/*methods
Neurosurgical Procedures/*methods
Surgery, Computer-Assisted/*methods
Adolescent ; Adult ; Algorithms ; Child ; Drug Resistant Epilepsy/surgery ; Electrodes, Implanted ; Electroencephalography ; Embolization, Therapeutic ; Female ; Humans ; Image Processing, Computer-Assisted ; Male ; Retrospective Studies ; Stereotaxic Techniques ; Tomography, Emission-Computed, Single-Photon ; Young Adult
Czasopismo naukowe

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