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Tytuł:
Novel artesunate and isatin hybrid CT3-1 suppresses collagen-induced arthritis through abrogating dendritic cell chemotaxis-induced by CCR5.
Autorzy:
He J; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China.
Lin X; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China.
Gao X; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China.
Luan H; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China.
Guo Y; Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs; The First Dongguan Affiliated Hospital and School of Pharmacy, Guangdong Medical University, Dongguan 523808, China.
Wang X; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China.
Tao C; Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs; The First Dongguan Affiliated Hospital and School of Pharmacy, Guangdong Medical University, Dongguan 523808, China. Electronic address: .
Wang Q; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China. Electronic address: .
Chen J; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen 518036, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Jul 30; Vol. 136, pp. 112264. Date of Electronic Publication: 2024 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/drug effects
Dendritic Cells*/immunology
Receptors, CCR5*/metabolism
Arthritis, Experimental*/drug therapy
Arthritis, Experimental*/immunology
Chemotaxis*/drug effects
Artesunate*/pharmacology
Artesunate*/therapeutic use
Arthritis, Rheumatoid*/drug therapy
Arthritis, Rheumatoid*/immunology
Animals ; Mice ; Mice, Inbred DBA ; Male ; Cells, Cultured ; Humans
Czasopismo naukowe
Tytuł:
The Toxoplasma secreted effector TgWIP modulates dendritic cell motility by activating host tyrosine phosphatases Shp1 and Shp2.
Autorzy:
Morales P; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA.
Brown AJ; Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA, USA.
Sangaré LO; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA.
Yang S; Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA, USA.; Target & Protein Sciences, Johnson & Johnson, New Brunswick, USA.
Kuihon SVNP; Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA, USA.
Chen B; Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA, USA.
Saeij JPJ; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA. .
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Źródło:
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Jul 09; Vol. 81 (1), pp. 294. Date of Electronic Publication: 2024 Jul 09.
Typ publikacji:
Journal Article
MeSH Terms:
Toxoplasma*/metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 11*/metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 11*/genetics
Dendritic Cells*/metabolism
Dendritic Cells*/parasitology
Cell Movement*
Protein Tyrosine Phosphatase, Non-Receptor Type 6*/metabolism
Protozoan Proteins*/metabolism
Protozoan Proteins*/genetics
Animals ; Humans ; Mice ; rho-Associated Kinases/metabolism ; Toxoplasmosis/metabolism ; Toxoplasmosis/parasitology ; Toxoplasmosis/pathology ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Administration of ROS-Scavenging Cerium Oxide Nanoparticles Simply Mixed with Autoantigenic Peptides Induce Antigen-Specific Immune Tolerance against Autoimmune Encephalomyelitis.
Autorzy:
Nguyen TL; School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
Phan NM; School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
Kim J; School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.; Institute of Quantum Biophysics (IQB), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.; Department of MetaBioHealth, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
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Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Jul 03; Vol. 16 (26), pp. 33106-33120. Date of Electronic Publication: 2024 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
Cerium*/chemistry
Cerium*/pharmacology
Reactive Oxygen Species*/metabolism
Encephalomyelitis, Autoimmune, Experimental*/immunology
Encephalomyelitis, Autoimmune, Experimental*/drug therapy
Nanoparticles*/chemistry
Dendritic Cells*/immunology
Dendritic Cells*/drug effects
Immune Tolerance*/drug effects
Peptides*/chemistry
Peptides*/pharmacology
Peptides*/immunology
Animals ; Mice ; Mice, Inbred C57BL ; Autoantigens/immunology ; Autoantigens/chemistry ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/drug effects ; Female ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/pharmacology
Czasopismo naukowe
Tytuł:
High expression of PD-L1 on conventional dendritic cells in tumour-draining lymph nodes is associated with poor prognosis in oral cancer.
Autorzy:
Eric H; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Piersiala K; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.; Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Lagebro V; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Farrajota Neves Da Silva P; Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden.
Petro M; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Starkhammar M; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.; Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Elliot A; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.; Department of Head and Neck Surgery, Medical Unit Head Neck Lung and Skin Cancer, Karolinska University Hospital, Stockholm, Sweden.
Bark R; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.; Department of Head and Neck Surgery, Medical Unit Head Neck Lung and Skin Cancer, Karolinska University Hospital, Stockholm, Sweden.
Margolin G; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.; Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Kumlien Georén S; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Cardell LO; Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden. .; Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden. .
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Źródło:
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2024 Jul 02; Vol. 73 (9), pp. 165. Date of Electronic Publication: 2024 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Mouth Neoplasms*/pathology
Mouth Neoplasms*/immunology
Mouth Neoplasms*/metabolism
Lymph Nodes*/pathology
Lymph Nodes*/immunology
Lymph Nodes*/metabolism
B7-H1 Antigen*/metabolism
Humans ; Prognosis ; Female ; Male ; Middle Aged ; Aged ; Lymphatic Metastasis ; Carcinoma, Squamous Cell/immunology ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/metabolism ; Biomarkers, Tumor/metabolism ; Adult
Czasopismo naukowe
Tytuł:
Constitutive Flt3 signaling impacts conventional dendritic cell function.
Autorzy:
Wilson KR; Department of Biochemistry and Pharmacology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, Parkville, VIC, Australia.
Macri C; Department of Biochemistry and Pharmacology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, Parkville, VIC, Australia.
Villadangos JA; Department of Biochemistry and Pharmacology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, Parkville, VIC, Australia.; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, Australia.
Mintern JD; Department of Biochemistry and Pharmacology, The University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, Parkville, VIC, Australia.
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Źródło:
Immunology and cell biology [Immunol Cell Biol] 2024 Jul; Vol. 102 (6), pp. 500-512. Date of Electronic Publication: 2024 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
fms-Like Tyrosine Kinase 3*/metabolism
Signal Transduction*
Antigen Presentation*
Animals ; Mice ; Mice, Inbred C57BL ; Cytokines/metabolism ; Cell Differentiation
Czasopismo naukowe
Tytuł:
K33 only mutant ubiquitin augments bone marrow-derived dendritic cell-mediated CTL priming via PI3K-Akt pathway.
Autorzy:
Liang YY; Department of Basic Medicine Science, School of Medicine, Xiamen University, Xiamen, Fujian, People's Republic of China.
Liao XY; Department of Basic Medicine Science, School of Medicine, Xiamen University, Xiamen, Fujian, People's Republic of China.
Jia JJ; Department of Basic Medicine Science, School of Medicine, Xiamen University, Xiamen, Fujian, People's Republic of China.
Yin YZ; Department of Basic Medicine Science, School of Medicine, Xiamen University, Xiamen, Fujian, People's Republic of China.
Zhang YH; Laboratory Animal Center, Xiamen University, Xiamen, Fujian, People's Republic of China.
Gao FG; Department of Basic Medicine Science, School of Medicine, Xiamen University, Xiamen, Fujian, People's Republic of China.
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Źródło:
Immunology [Immunology] 2024 Jul; Vol. 172 (3), pp. 486-499. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Proto-Oncogene Proteins c-akt*/metabolism
Ubiquitin*/metabolism
Signal Transduction*
T-Lymphocytes, Cytotoxic*/immunology
Bone Marrow Cells*/immunology
Bone Marrow Cells*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Antigen Presentation*/immunology
Animals ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Lymphocyte Activation ; Cell Differentiation ; Mutation ; Morpholines/pharmacology ; Lymphocyte Culture Test, Mixed ; Cell Proliferation ; B7-2 Antigen/metabolism ; B7-2 Antigen/genetics ; B7-2 Antigen/immunology ; Cells, Cultured ; Chromones/pharmacology ; Wortmannin/pharmacology ; Androstadienes/pharmacology
Czasopismo naukowe
Tytuł:
Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis.
Autorzy:
Maio M; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad de Buenos Aires, Buenos Aires, Argentina.
Barros J; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad de Buenos Aires, Buenos Aires, Argentina.
Joly M; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Vahlas Z; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Marín Franco JL; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.
Genoula M; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.
Monard SC; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Vecchione MB; Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad de Buenos Aires, Buenos Aires, Argentina.
Fuentes F; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.
Gonzalez Polo V; Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad de Buenos Aires, Buenos Aires, Argentina.
Quiroga MF; Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad de Buenos Aires, Buenos Aires, Argentina.
Vermeulen M; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.
Vu Manh TP; Aix Marseille University, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Argüello RJ; Aix Marseille University, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Inwentarz S; Instituto Prof. Dr. Raúl Vaccarezza and Hospital de Infecciosas Dr. F.J. Muñiz, Buenos Aires, Argentina.
Musella R; Instituto Prof. Dr. Raúl Vaccarezza and Hospital de Infecciosas Dr. F.J. Muñiz, Buenos Aires, Argentina.
Ciallella L; Instituto Prof. Dr. Raúl Vaccarezza and Hospital de Infecciosas Dr. F.J. Muñiz, Buenos Aires, Argentina.
González Montaner P; Instituto Prof. Dr. Raúl Vaccarezza and Hospital de Infecciosas Dr. F.J. Muñiz, Buenos Aires, Argentina.
Palmero D; Instituto Prof. Dr. Raúl Vaccarezza and Hospital de Infecciosas Dr. F.J. Muñiz, Buenos Aires, Argentina.
Lugo Villarino G; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Sasiain MDC; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.
Neyrolles O; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Vérollet C; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France.
Balboa L; Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.; International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina / International Research Project Toulouse, Toulouse, France.; Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad de Buenos Aires, Buenos Aires, Argentina.
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Źródło:
ELife [Elife] 2024 Jun 26; Vol. 12. Date of Electronic Publication: 2024 Jun 26.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/metabolism
Dendritic Cells*/immunology
Glycolysis*
Monocytes*/metabolism
Monocytes*/immunology
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Mycobacterium tuberculosis*/immunology
Cell Movement*
Tuberculosis*/immunology
Tuberculosis*/metabolism
Tuberculosis*/microbiology
Humans ; Animals ; Mice ; Toll-Like Receptor 2/metabolism ; Mice, Inbred C57BL ; Female
Czasopismo naukowe
Tytuł:
Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells.
Autorzy:
Audu CO; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.
Wolf SJ; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Joshi AD; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Moon JY; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Melvin WJ; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Sharma SB; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Davis FM; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Obi AT; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Wasikowski R; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Tsoi LC; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Barrett EC; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Mangum KD; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Bauer TM; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Kunkel SL; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Pathology, School of Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Moore BB; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Gallagher KA; Section of Vascular Surgery, Department of Surgery, and.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
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Źródło:
JCI insight [JCI Insight] 2024 Jun 24; Vol. 9 (12). Date of Electronic Publication: 2024 Jun 24.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Interleukin-6*/metabolism
Th17 Cells*/immunology
Th17 Cells*/metabolism
Wound Healing*/immunology
Animals ; Female ; Humans ; Male ; Mice ; Interleukin-17/metabolism ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Jumonji Domain-Containing Histone Demethylases/genetics ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
On-Site Stimulation of Dendritic Cells by Cancer-Derived Extracellular Vesicles on a Core-Shell Nanowire Platform.
Autorzy:
Zhang M; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
Ono M; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
Kawaguchi S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
Iida M; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
Chattrairat K; Department of Life Science and Technology, Tokyo Institute of Technology, Nagatsuta 4259, Midori-ku, Yokohama 226-8501, Japan.
Zhu Z; Department of Life Science and Technology, Tokyo Institute of Technology, Nagatsuta 4259, Midori-ku, Yokohama 226-8501, Japan.
Nagashima K; Research Institute for Electronic Science (RIES), Hokkaido University, Kita, Sapporo, Hokkaido 001-0020, Japan.
Yanagida T; Department of Applied Chemistry, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Yamaguchi J; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Nishikawa H; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.; Division of Cancer Immunology, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Chiba 277-8577, Japan.
Natsume A; Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.; Kawamura Medical Society, Gifu 501-3144, Japan.
Baba Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.; Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.; Institute for Quantum Life Science, National Institutes for Quantum Science and Technology (QST), Anagawa 4-9-1, Inage-ku, Chiba 263-8555, Japan.
Yasui T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.; Department of Life Science and Technology, Tokyo Institute of Technology, Nagatsuta 4259, Midori-ku, Yokohama 226-8501, Japan.; Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.; Institute for Quantum Life Science, National Institutes for Quantum Science and Technology (QST), Anagawa 4-9-1, Inage-ku, Chiba 263-8555, Japan.
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Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Jun 12; Vol. 16 (23), pp. 29570-29580. Date of Electronic Publication: 2024 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Nanowires*/chemistry
Extracellular Vesicles*/chemistry
Neoplasms*/therapy
Neoplasms*/pathology
Neoplasms*/immunology
Humans ; Immunotherapy ; Zinc Oxide/chemistry ; Animals ; Cell Line, Tumor ; Mice
Czasopismo naukowe
Tytuł:
Targeting dendritic cell activation: the therapeutic impact of paeoniflorin in cortosteroid-dependent dermatitis management.
Autorzy:
Chen J; Department of Dermatology, Hubei Provincial Hospital of Traditional Chinese Medicine, No. 4 Huayuanshan, Wuchang District, Wuhan, Hubei Province, 430061, China.
He Q; Department of Dermatology, Hubei Provincial Hospital of Traditional Chinese Medicine, No. 4 Huayuanshan, Wuchang District, Wuhan, Hubei Province, 430061, China.
Jin J; Department of Dermatology, Hubei Provincial Hospital of Traditional Chinese Medicine, No. 4 Huayuanshan, Wuchang District, Wuhan, Hubei Province, 430061, China. .
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Źródło:
Archives of dermatological research [Arch Dermatol Res] 2024 Jun 07; Vol. 316 (7), pp. 348. Date of Electronic Publication: 2024 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/drug effects
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Glucosides*/pharmacology
Glucosides*/therapeutic use
Cytokines*/metabolism
Monoterpenes*/pharmacology
Monoterpenes*/therapeutic use
Animals ; Humans ; Mice ; Dermatitis/drug therapy ; Dermatitis/immunology ; Dermatitis/metabolism ; Interleukin-6/metabolism ; Molecular Docking Simulation ; Skin/pathology ; Skin/drug effects ; Skin/immunology ; Skin/metabolism ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Disease Models, Animal ; B7-1 Antigen/metabolism ; B7-2 Antigen/metabolism ; Male ; Thymic Stromal Lymphopoietin ; Lymphocyte Activation/drug effects
Czasopismo naukowe
Tytuł:
Factor of time in dendritic cell (DC) maturation: short-term activation of DCs significantly improves type 1 cytokine production and T cell responses.
Autorzy:
Poženel P; Slovenian Institute for Transfusion Medicine, Šlajmerjeva 6, Ljubljana, 1000, Slovenia.; Faculty of Medicine, University of Ljubljana, Korytkova ulica 2, Ljubljana, 1000, Slovenia.
Zajc K; Slovenian Institute for Transfusion Medicine, Šlajmerjeva 6, Ljubljana, 1000, Slovenia.
Švajger U; Slovenian Institute for Transfusion Medicine, Šlajmerjeva 6, Ljubljana, 1000, Slovenia. .; Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, Ljubljana, 1000, Slovenia. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jun 06; Vol. 22 (1), pp. 541. Date of Electronic Publication: 2024 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Cell Differentiation*
Cytokines*/metabolism
Humans ; Time Factors ; Lymphocyte Activation/immunology ; T-Lymphocytes/immunology ; CD40 Ligand/metabolism ; CD8-Positive T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł:
Dendritic Cell Immune Modulation via Polyphenol Membrane Coatings.
Autorzy:
Janes ME; Harvard-MIT Division of Health Sciences & Technology, Cambridge, Massachusetts 02139, United States.; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
Park KS; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
Gottlieb AP; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
Curreri A; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
Adebowale K; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
Kim J; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
Mitragotri S; John A Paulson School of Engineering & Applied Sciences, Allston, Massachusetts 02134, United States.; Wyss Institute of Biologically Inspired Engineering, Boston, Massachusetts 02215, United States.
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Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Jun 05; Vol. 16 (22), pp. 28070-28079. Date of Electronic Publication: 2024 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/drug effects
Dendritic Cells*/immunology
Tannins*/chemistry
Tannins*/pharmacology
Polyphenols*/chemistry
Polyphenols*/pharmacology
Humans ; Animals ; Coated Materials, Biocompatible/chemistry ; Coated Materials, Biocompatible/pharmacology ; Mice ; Cell Membrane/metabolism ; Cell Survival/drug effects
Czasopismo naukowe
Tytuł:
NRF2 Plays a Crucial Role in the Tolerogenic Effect of Ethyl Pyruvate on Dendritic Cells.
Autorzy:
Stanisavljević S; Department of Immunology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Stegnjaić G; Department of Immunology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Jevtić B; Department of Immunology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Dimitrijević M; Department of Immunology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Miljković Đ; Department of Immunology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Lavrnja I; Department of Neurobiology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Nikolovski N; Department of Immunology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jun 04; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 04.
Typ publikacji:
Journal Article
MeSH Terms:
NF-E2-Related Factor 2*/metabolism
Dendritic Cells*/drug effects
Dendritic Cells*/metabolism
Dendritic Cells*/immunology
Pyruvates*/pharmacology
NF-kappa B*/metabolism
Lipopolysaccharides*/pharmacology
Signal Transduction*/drug effects
Animals ; Mice ; Cell Differentiation/drug effects ; Mice, Inbred C57BL ; Immune Tolerance/drug effects ; Cells, Cultured
Czasopismo naukowe
Tytuł:
NECA alleviates inflammatory responses in diabetic retinopathy through dendritic cell toll-like receptor signaling pathway.
Autorzy:
Li L; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Chen J; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Wang Z; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Xu Y; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Yao H; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Lei W; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Zhou X; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
Zheng M; The Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Jun 04; Vol. 15, pp. 1415004. Date of Electronic Publication: 2024 Jun 04 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Diabetic Retinopathy*/immunology
Diabetic Retinopathy*/metabolism
Signal Transduction*
Mice, Inbred C57BL*
Toll-Like Receptors*/metabolism
Animals ; Mice ; Humans ; Male ; Diabetes Mellitus, Experimental/immunology ; Female ; Th17 Cells/immunology ; Th17 Cells/metabolism ; Cytokines/metabolism ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Middle Aged ; Inflammation/immunology
Czasopismo naukowe
Tytuł:
Amniotic fluid stem cell-derived extracellular vesicles educate type 2 conventional dendritic cells to rescue autoimmune disorders in a multiple sclerosis mouse model.
Autorzy:
Manni G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.; Extracellular Vesicles network (EV-net) of the University of Perugia, Perugia, Italy.
Gargaro M; Department of Pharmaceutical Science, University of Perugia, Perugia, Italy.
Ricciuti D; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Fontana S; Department of Biomedicine, Neurosciences and advanced Diagnostics (Bi.N.D) School of Medicine, University of Palermo, Palermo, Italy.
Padiglioni E; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Cipolloni M; TES Pharma Srl, I, Corciano, Perugia, Italy.
Mazza T; Bioinformatics unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
Rosati J; Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
di Veroli A; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
Mencarelli G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Pieroni B; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Silva Barcelos EC; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Scalisi G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Sarnari F; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
di Michele A; Extracellular Vesicles network (EV-net) of the University of Perugia, Perugia, Italy.; Department of Physics and Geology, University of Perugia, Perugia, Italy.
Pascucci L; Extracellular Vesicles network (EV-net) of the University of Perugia, Perugia, Italy.; Department of Veterinary Medicine, University of Perugia, Perugia, Italy.
de Franco F; TES Pharma Srl, I, Corciano, Perugia, Italy.
Zelante T; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Antognelli C; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Cruciani G; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
Talesa VN; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Romani R; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.; Extracellular Vesicles network (EV-net) of the University of Perugia, Perugia, Italy.
Fallarino F; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.; Extracellular Vesicles network (EV-net) of the University of Perugia, Perugia, Italy.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jun; Vol. 13 (6), pp. e12446.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*/metabolism
Extracellular Vesicles*/immunology
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Amniotic Fluid*/cytology
Amniotic Fluid*/metabolism
Encephalomyelitis, Autoimmune, Experimental*/immunology
Encephalomyelitis, Autoimmune, Experimental*/therapy
Encephalomyelitis, Autoimmune, Experimental*/metabolism
Disease Models, Animal*
Multiple Sclerosis*/therapy
Multiple Sclerosis*/immunology
Multiple Sclerosis*/metabolism
Animals ; Mice ; Humans ; Female ; Stem Cells/metabolism ; Stem Cells/cytology ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
cDC2 plasticity and acquisition of a DC3-like phenotype mediated by IL-6 and PGE2 in a patient-derived colorectal cancer organoids model.
Autorzy:
Subtil B; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
van der Hoorn IAE; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
Cuenca-Escalona J; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
Becker AMD; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
Alvarez-Begue M; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
Iyer KK; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.
Janssen J; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.
van Oorschot T; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
Poel D; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.
Gorris MAJ; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
van den Dries K; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
Cambi A; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
Tauriello DVF; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, the Netherlands.
de Vries IJM; Department of Medical BioSciences (MBS), Radboud University Medical Center, Nijmegen, the Netherlands.
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Źródło:
European journal of immunology [Eur J Immunol] 2024 Jun; Vol. 54 (6), pp. e2350891. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/immunology
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Organoids*/immunology
Organoids*/metabolism
Dinoprostone*/metabolism
Interleukin-6*/metabolism
Interleukin-6*/immunology
Humans ; Coculture Techniques ; Phenotype ; Cell Plasticity
Czasopismo naukowe
Tytuł:
Optimal conditions for adenoviral transduction of immature dendritic cells without affecting the tolerogenic activity of DC-based immunotherapy.
Autorzy:
Jian Q; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Fu Z; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Wang H; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Zhang H; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Ma Y; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: .
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Źródło:
Journal of virological methods [J Virol Methods] 2024 Jun; Vol. 327, pp. 114921. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Dendritic Cells*/immunology
Adenoviridae*/genetics
Transduction, Genetic*
Immunotherapy*/methods
Genetic Vectors*/genetics
Animals ; Mice ; Heart Transplantation ; Mice, Inbred C57BL ; Interleukin-6/metabolism ; Immune Tolerance ; B7-1 Antigen/genetics ; B7-1 Antigen/metabolism ; Th1 Cells/immunology ; Th17 Cells/immunology ; B7-2 Antigen/metabolism ; B7-2 Antigen/genetics
Czasopismo naukowe
Tytuł:
Myelin Oligodendrocyte Glycoprotein (MOG)35-55 Mannan Conjugate Induces Human T-Cell Tolerance and Can Be Used as a Personalized Therapy for Multiple Sclerosis.
Autorzy:
Rodi M; Laboratory of Immunohematology, Medical School, University of Patras, 26500 Patras, Greece.
de Lastic AL; Laboratory of Immunohematology, Medical School, University of Patras, 26500 Patras, Greece.
Panagoulias I; Laboratory of Immunohematology, Medical School, University of Patras, 26500 Patras, Greece.
Aggeletopoulou I; Laboratory of Immunohematology, Medical School, University of Patras, 26500 Patras, Greece.
Kelaidonis K; NewDrug P.C., Patras Science Park, 26504 Patras, Greece.
Matsoukas J; NewDrug P.C., Patras Science Park, 26504 Patras, Greece.; Immunology and Translational Research, Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N1N4, Canada.; Department of Chemistry, University of Patras, 26504 Patras, Greece.
Apostolopoulos V; Immunology and Translational Research, Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.; Immunology Program, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne, VIC 3021, Australia.
Mouzaki A; Laboratory of Immunohematology, Medical School, University of Patras, 26500 Patras, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 31; Vol. 25 (11). Date of Electronic Publication: 2024 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Myelin-Oligodendrocyte Glycoprotein*/immunology
Dendritic Cells*/immunology
Dendritic Cells*/metabolism
Multiple Sclerosis*/immunology
Multiple Sclerosis*/therapy
Multiple Sclerosis*/drug therapy
Immune Tolerance*/drug effects
Humans ; Peptide Fragments/immunology ; Peptide Fragments/pharmacology ; Adult ; Female ; Mannans/pharmacology ; Male ; Cell Differentiation/drug effects ; Monocytes/immunology ; Monocytes/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Cells, Cultured ; Middle Aged ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cytokines/metabolism
Czasopismo naukowe
Tytuł:
Dengue virus exploits autophagy vesicles and secretory pathways to promote transmission by human dendritic cells.
Autorzy:
Cloherty APM; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.
Rader AG; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands.
Patel KS; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.
Eisden TTHD; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
van Piggelen S; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.
Schreurs RRCE; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands.
Ribeiro CMS; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, Netherlands.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 May 28; Vol. 15, pp. 1260439. Date of Electronic Publication: 2024 May 28 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Dengue Virus*/physiology
Dendritic Cells*/immunology
Dendritic Cells*/virology
Dendritic Cells*/metabolism
Autophagy*
Dengue*/transmission
Dengue*/virology
Dengue*/immunology
Autophagosomes*/metabolism
Secretory Pathway*
Virus Replication*
Humans ; Extracellular Vesicles/metabolism ; Extracellular Vesicles/virology ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Batf3 DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy.
Autorzy:
Ziblat A; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.
Horton BL; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.
Higgs EF; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.
Hatogai K; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.
Martinez A; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.
Shapiro JW; Center for Research Informatics, University of Chicago, Chicago, IL 60637, USA.
Kim DEC; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.
Zha Y; Human Immunological Monitoring Facility, University of Chicago, Chicago, IL 60637, USA.
Sweis RF; Department of Medicine, University of Chicago, Chicago, IL 60612, USA.
Gajewski TF; Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA; Department of Medicine, University of Chicago, Chicago, IL 60612, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2024 May 28; Vol. 43 (5), pp. 114141. Date of Electronic Publication: 2024 Apr 23.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
Basic-Leucine Zipper Transcription Factors*/metabolism
Basic-Leucine Zipper Transcription Factors*/genetics
CD8-Positive T-Lymphocytes*/immunology
CD8-Positive T-Lymphocytes*/metabolism
Dendritic Cells*/metabolism
Dendritic Cells*/immunology
Programmed Cell Death 1 Receptor*/metabolism
Programmed Cell Death 1 Receptor*/antagonists & inhibitors
Repressor Proteins*/metabolism
Tumor Microenvironment*
Animals ; Humans ; Mice ; 4-1BB Ligand/metabolism ; 4-1BB Ligand/genetics ; Cell Line, Tumor ; Immune Checkpoint Inhibitors/pharmacology ; Mice, Inbred C57BL ; Signal Transduction ; Tumor Necrosis Factor Receptor Superfamily, Member 9/metabolism
Czasopismo naukowe

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