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Tytuł :
Feasibility of using monocyte-derived dendritic cells obtained from cryopreserved cells for DC-based vaccines.
Autorzy :
Usero L; AIDS Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: .
Miralles L; AIDS Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: .
Esteban I; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address: .
Pastor-Quiñones C; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address: .
Maleno MJ; AIDS Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: .
Leal L; Infectious Diseases Service and AIDS Research Group, IDIBAPS - Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: .
García F; Infectious Diseases Service and AIDS Research Group, IDIBAPS - Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: .
Plana M; AIDS Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Nov; Vol. 498, pp. 113133. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Cryopreservation*
Dendritic Cells/*immunology
Monocytes/*immunology
Vaccines/*immunology
Cell Proliferation ; Cell Survival ; Cells, Cultured ; Coculture Techniques ; Cytokines/metabolism ; Dendritic Cells/metabolism ; Dendritic Cells/transplantation ; Feasibility Studies ; Flow Cytometry ; Humans ; Lymphocyte Activation ; Lymphocyte Culture Test, Mixed ; Phenotype ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells.
Autorzy :
Yang D; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Chu H; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Lu G; Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Medical University, Haikou, People's Republic of China.; Hainan-Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Hainan Medical University, Haikou, Hainan, People's Republic of China, and the The University of Hong Kong, Pokfulam, People's Republic of China.; Department of Pathogen Biology, Hainan Medical University, Haikou, Hainan, People's Republic of China.
Shuai H; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Wang Y; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Hou Y; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Zhang X; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Huang X; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Hu B; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Chai Y; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Yuen TT; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Zhao X; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Lee AC; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Ye Z; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Li C; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Chik KK; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Zhang AJ; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Zhou J; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Yuan S; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.
Chan JF; State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Pokfulam, People's Republic of China.; Hainan-Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Hainan Medical University, Haikou, Hainan, People's Republic of China, and the The University of Hong Kong, Pokfulam, People's Republic of China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, People's Republic of China.; Department of Microbiology, Queen Mary Hospital, Pokfulam, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 1024-1037.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Dendritic Cells/*virology
Macrophages/*virology
STAT1 Transcription Factor/*metabolism
STAT2 Transcription Factor/*metabolism
Zika Virus/*physiology
Animals ; Cell Line ; Chlorocebus aethiops ; Dendritic Cells/drug effects ; Dendritic Cells/metabolism ; Gene Knockout Techniques ; Humans ; Interferon Type I/pharmacology ; Macrophages/drug effects ; Macrophages/metabolism ; Phosphorylation ; STAT1 Transcription Factor/genetics ; STAT2 Transcription Factor/genetics ; Vero Cells ; Virus Replication ; Zika Virus Infection/metabolism
Czasopismo naukowe
Tytuł :
Distinct antigen uptake receptors route to the same storage compartments for cross-presentation in dendritic cells.
Autorzy :
Ho NI; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
Camps MG; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
Garcia-Vallejo JJ; Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.
Bos E; Department of Molecular Cell Biology, Section Electron Microscopy, Leiden University Medical Center, Leiden, The Netherlands.
Koster AJ; Department of Molecular Cell Biology, Section Electron Microscopy, Leiden University Medical Center, Leiden, The Netherlands.
Verdoes M; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
van Kooyk Y; Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.
Ossendorp F; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
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Źródło :
Immunology [Immunology] 2021 Nov; Vol. 164 (3), pp. 494-506. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cross-Priming*
Antigens/*metabolism
Dendritic Cells/*immunology
Lectins, C-Type/*metabolism
Receptors, IgG/*metabolism
Animals ; Antigen Presentation ; Antigens/immunology ; Cathepsins/metabolism ; Dendritic Cells/metabolism ; Dendritic Cells/ultrastructure ; Endosomes/immunology ; Endosomes/metabolism ; Endosomes/ultrastructure ; Histocompatibility Antigens Class I/metabolism ; Histocompatibility Antigens Class II/metabolism ; Lysosomes/immunology ; Lysosomes/metabolism ; Lysosomes/ultrastructure ; Mice ; Microscopy, Electron, Transmission ; Models, Animal ; NIH 3T3 Cells ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity.
Autorzy :
Sharma MD; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Department of Pediatrics, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Pacholczyk R; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Shi H; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Berrong ZJ; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Zakharia Y; Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.
Greco A; Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.
Chang CS; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Georgia Cancer Center, Bioinformatics Shared Resource, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Eathiraj S; ArQule, Burlington, MA 01803, USA.
Kennedy E; Lumos Pharma, Ames, IA 50010, USA.
Cash T; Department of Pediatrics, Emory University, Atlanta, GA 30322, USA.
Bollag RJ; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Kolhe R; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Sadek R; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
McGaha TL; Department of Immunology, University of Toronto, Toronto, ON M5G 2M9, Canada.
Rodriguez P; Immunology Department, Moffitt Cancer Center, Tampa, FL 33612, USA.
Mandula J; Immunology Department, Moffitt Cancer Center, Tampa, FL 33612, USA.
Blazar BR; Department of Pediatrics and Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.
Johnson TS; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Department of Pediatrics, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Munn DH; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Department of Pediatrics, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. Electronic address: .
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Źródło :
Immunity [Immunity] 2021 Oct 12; Vol. 54 (10), pp. 2354-2371.e8. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation/*immunology
Dendritic Cells/*immunology
Neoplasms/*immunology
T-Lymphocytes/*immunology
Agammaglobulinaemia Tyrosine Kinase/immunology ; Agammaglobulinaemia Tyrosine Kinase/metabolism ; Animals ; Dendritic Cells/cytology ; Dendritic Cells/metabolism ; Female ; Humans ; Indoleamine-Pyrrole 2,3,-Dioxygenase/immunology ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Male ; Mice ; Monocytes/cytology ; Monocytes/immunology ; Monocytes/metabolism ; Signal Transduction/immunology ; T-Lymphocytes/metabolism ; TOR Serine-Threonine Kinases/immunology ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
The PI3Kδ inhibitor idelalisib impairs the function of human dendritic cells.
Autorzy :
Braun C; Medical Clinic III, Clinic for Oncology, Hematology, Immuno-Oncology and Rheumatology/Clinical Immunology, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.
Schlaweck S; Medical Clinic III, Clinic for Oncology, Hematology, Immuno-Oncology and Rheumatology/Clinical Immunology, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.; Faculty of Medicine, Mildred Scheel School of Oncology Aachen Bonn Cologne Düsseldorf (MSSO ABCD), University Hospital of Bonn, 53127, Bonn, Germany.
Daecke SN; Medical Clinic III, Clinic for Oncology, Hematology, Immuno-Oncology and Rheumatology/Clinical Immunology, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.
Brossart P; Medical Clinic III, Clinic for Oncology, Hematology, Immuno-Oncology and Rheumatology/Clinical Immunology, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.
Heine A; Medical Clinic III, Clinic for Oncology, Hematology, Immuno-Oncology and Rheumatology/Clinical Immunology, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Dec; Vol. 70 (12), pp. 3693-3700. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Class I Phosphatidylinositol 3-Kinases/*antagonists & inhibitors
Dendritic Cells/*drug effects
Purines/*pharmacology
Quinazolinones/*pharmacology
Cell Differentiation/drug effects ; Cells, Cultured ; Dendritic Cells/metabolism ; Humans ; Immunity/drug effects ; Interleukin-12/metabolism ; Monocytes/drug effects ; Monocytes/metabolism ; NF-kappa B/metabolism ; Signal Transduction/drug effects ; T-Lymphocytes/drug effects ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Comparability study of monocyte derived dendritic cells, primary monocytes, and THP1 cells for innate immune responses.
Autorzy :
Wen Y; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
Wang X; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Cahya S; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Anderson P; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Velasquez C; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Torres C; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Ferrante A; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.
Kaliyaperumal A; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Nov; Vol. 498, pp. 113147. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Dendritic Cells/*drug effects
Immunity, Innate/*drug effects
Monocytes/*drug effects
Antibodies, Monoclonal, Humanized/pharmacology ; Antigen Presentation ; Automation, Laboratory ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Endocytosis ; Flow Cytometry ; High-Throughput Screening Assays ; Humans ; Infliximab/pharmacology ; Monocytes/immunology ; Monocytes/metabolism ; THP-1 Cells
Czasopismo naukowe
Tytuł :
How dendritic cells sense and respond to viral infections.
Autorzy :
Marongiu L; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.; National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.
Valache M; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.
Facchini FA; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.
Granucci F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.; National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.
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Źródło :
Clinical science (London, England : 1979) [Clin Sci (Lond)] 2021 Oct 14; Vol. 135 (19), pp. 2217-2242.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*virology
Dendritic Cells/*virology
Receptors, Pattern Recognition/*immunology
SARS-CoV-2/*pathogenicity
Virus Diseases/*virology
Cytokines/immunology ; Dendritic Cells/immunology ; Humans ; Virus Diseases/immunology
Czasopismo naukowe
Tytuł :
Dendritic cell Flt3 - regulation, roles and repercussions for immunotherapy.
Autorzy :
Wilson KR; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
Villadangos JA; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, Australia.
Mintern JD; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
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Źródło :
Immunology and cell biology [Immunol Cell Biol] 2021 Oct; Vol. 99 (9), pp. 962-971. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Dendritic Cells*
fms-Like Tyrosine Kinase 3*/genetics
Immunologic Factors ; Immunotherapy ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
Applicability of different cell line-derived dendritic cell-like cells in autophagy research.
Autorzy :
Prins MMC; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
van Roest M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Vermeulen JLM; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Tjabringa GS; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Koelink PJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Wildenberg ME; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Oct; Vol. 497, pp. 113106. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell Differentiation*
Adenine/*analogs & derivatives
Autophagy/*drug effects
Dendritic Cells/*drug effects
Macrolides/*pharmacology
Monocytes/*immunology
Sirolimus/*pharmacology
Adenine/pharmacology ; Autophagy/genetics ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Dendritic Cells/pathology ; Flow Cytometry ; Genotype ; HL-60 Cells ; Humans ; Microscopy, Fluorescence ; Monocytes/metabolism ; Monocytes/pathology ; Phenotype ; Polymorphism, Single Nucleotide ; THP-1 Cells ; U937 Cells
Czasopismo naukowe
Tytuł :
Large-Sized Graphene Oxide Nanosheets Increase DC-T-Cell Synaptic Contact and the Efficacy of DC Vaccines against SARS-CoV-2.
Autorzy :
Zhou Q; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Gu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Sun S; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Zhang Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Hou Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Li C; BGI college, Zhengzhou University, Henan Institute of Medical and Pharmaceutical Science, Zhengzhou University, Zhengzhou, 450001, P. R. China.
Zhao Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Ma P; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Lv L; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Aji S; Cold Spring Biotech Corporation, Beijing, 110000, P. R. China.
Sun S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Wang X; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.
Zhan L; Institute of Health Service and Transfusion Medicine, Beijing, 100850, P. R. China.; BGI college, Zhengzhou University, Henan Institute of Medical and Pharmaceutical Science, Zhengzhou University, Zhengzhou, 450001, P. R. China.
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Źródło :
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2021 Oct; Vol. 33 (40), pp. e2102528. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*therapeutic use
COVID-19/*prevention & control
COVID-19 Vaccines/*therapeutic use
Dendritic Cells/*immunology
Graphite/*therapeutic use
Nanostructures/*therapeutic use
Adjuvants, Immunologic/chemistry ; Animals ; COVID-19/immunology ; COVID-19 Vaccines/immunology ; Dendritic Cells/drug effects ; Graphite/chemistry ; Humans ; Mice ; Nanostructures/chemistry ; SARS-CoV-2/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
E-Cadherin Expression and Blunted Interferon Response in Blastic Plasmacytoid Dendritic Cell Neoplasm.
Autorzy :
Lorenzi L; Department of Molecular and Translational Medicine, Section of Pathology.; Pathology Unit, ASST Spedali Civili di Brescia.
Lonardi S; Department of Molecular and Translational Medicine, Section of Pathology.; Pathology Unit, ASST Spedali Civili di Brescia.
Vairo D; Department of Molecular and Translational Medicine, A. Nocivelli Institute of Molecular Medicine, University of Brescia and Section of Medical Genetics, Spedali Civili.
Bernardelli A; Department of Molecular and Translational Medicine, Section of Pathology.
Tomaselli M; Pathology Unit, ASST Spedali Civili di Brescia.
Bugatti M; Department of Molecular and Translational Medicine, Section of Pathology.; Pathology Unit, ASST Spedali Civili di Brescia.
Licini S; Pathology Unit, ASST Spedali Civili di Brescia.
Arisi M; Department of Clinical and Experimental Sciences, Section of Dermatology, University of Brescia.
Cerroni L; Department of Dermatology, Medical University of Graz, Graz, Austria.
Tucci A; Haematology Unit, ASST Spedali Civili di Brescia, Brescia, Italy.
Vermi W; Department of Molecular and Translational Medicine, Section of Pathology.; Pathology Unit, ASST Spedali Civili di Brescia.; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO.
Giliani SC; Department of Molecular and Translational Medicine, A. Nocivelli Institute of Molecular Medicine, University of Brescia and Section of Medical Genetics, Spedali Civili.
Facchetti F; Department of Molecular and Translational Medicine, Section of Pathology.; Pathology Unit, ASST Spedali Civili di Brescia.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Oct 01; Vol. 45 (10), pp. 1428-1438.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*analysis
Biomarkers, Tumor/*analysis
Cadherins/*analysis
Dendritic Cells/*chemistry
Hematologic Neoplasms/*chemistry
Interferon Type I/*immunology
B7-H1 Antigen/analysis ; CD8-Positive T-Lymphocytes/immunology ; Cell Differentiation ; Dendritic Cells/immunology ; Dendritic Cells/pathology ; Hematologic Neoplasms/immunology ; Hematologic Neoplasms/pathology ; Humans ; Immunohistochemistry ; Lymphocytes, Tumor-Infiltrating/immunology ; Signal Transduction ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Naturally circulating pertactin-deficient Bordetella pertussis strains induce distinct gene expression and inflammatory signatures in human dendritic cells.
Autorzy :
Kroes MM; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Miranda-Bedate A; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Hovingh ES; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Jacobi R; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Schot C; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Pupo E; Institute for Translational Vaccinology (Intravacc), Bilthoven, Netherlands.
Raeven RHM; Institute for Translational Vaccinology (Intravacc), Bilthoven, Netherlands.
van der Ark AAJ; Institute for Translational Vaccinology (Intravacc), Bilthoven, Netherlands.
van Putten JPM; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
de Wit J; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Mariman R; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Pinelli E; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 1358-1368.
Typ publikacji :
Journal Article
MeSH Terms :
Transcriptome*
Bacterial Outer Membrane Proteins/*genetics
Bordetella pertussis/*immunology
Dendritic Cells/*immunology
Virulence Factors, Bordetella/*genetics
Adaptation, Biological ; Bacterial Outer Membrane Proteins/metabolism ; Bordetella pertussis/genetics ; Bordetella pertussis/metabolism ; Bordetella pertussis/pathogenicity ; Cytokines/genetics ; Cytokines/metabolism ; Dendritic Cells/metabolism ; Gene Expression Profiling ; Host-Pathogen Interactions ; Humans ; Inflammation ; Pertussis Vaccine/immunology ; Toll-Like Receptor 2/immunology ; Toll-Like Receptor 4/immunology ; Virulence Factors, Bordetella/metabolism ; Whooping Cough/microbiology
Czasopismo naukowe
Tytuł :
Circadian clocks guide dendritic cells into skin lymphatics.
Autorzy :
Holtkamp SJ; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Ince LM; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Barnoud C; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Schmitt MT; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.; Laboratory 'Cell Biology of the Immune System', Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Sinturel F; Department of Medicine, Division of Endocrinology, Diabetes, Nutrition and Patient Education, University Hospitals of Geneva, Geneva, Switzerland.; Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland.; Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland.
Pilorz V; Institute of Neurobiology, University of Lübeck, Lübeck, Germany.
Pick R; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Jemelin S; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Mühlstädt M; Division of Dermatology and Venereology, Department of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Boehncke WH; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Division of Dermatology and Venereology, Department of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Weber J; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Laubender D; Max Planck Institute of Neurobiology, Martinsried, Germany.
Philippou-Massier J; Laboratory for Functional Genome Analysis, Gene Center Munich, Ludwig-Maximilians-Universität Munich, Munich, Germany.
Chen CS; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Holtermann L; Department of Vascular Cell Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Vestweber D; Department of Vascular Cell Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Sperandio M; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Schraml BU; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Halin C; Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Dibner C; Department of Medicine, Division of Endocrinology, Diabetes, Nutrition and Patient Education, University Hospitals of Geneva, Geneva, Switzerland.; Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland.; Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland.
Oster H; Institute of Neurobiology, University of Lübeck, Lübeck, Germany.
Renkawitz J; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.; Laboratory 'Cell Biology of the Immune System', Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany.
Scheiermann C; Biomedical Center (BMC), Institute for Cardiovascular Physiology and Pathophysiology, Walter Brendel Center for Experimental Medicine (WBex), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Planegg-Martinsried, Germany. .; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Nov; Vol. 22 (11), pp. 1375-1381. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptive Immunity*
Chemotaxis*
Circadian Clocks*
Dendritic Cells/*immunology
Lymph Nodes/*immunology
Lymphatic Vessels/*immunology
Skin/*immunology
Aged ; Animals ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Cells, Cultured ; Chemokine CCL21/genetics ; Chemokine CCL21/metabolism ; Circadian Rhythm Signaling Peptides and Proteins/genetics ; Circadian Rhythm Signaling Peptides and Proteins/metabolism ; Dendritic Cells/metabolism ; Female ; Humans ; Lymph Nodes/metabolism ; Lymphatic Vessels/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Skin/metabolism ; Time Factors
Raport
Tytuł :
Immune control of Mycobacterium tuberculosis is dependent on both soluble TNFRp55 and soluble TNFRp75.
Autorzy :
Keeton R; Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa.
du Toit JP; Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa.
Hsu NJ; Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa.
Dube F; Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa.
Jacobs M; Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, South Africa.; National Health Laboratory Service, Johannesburg, South Africa.; Immunology of Infectious Disease Research Unit, University of Cape Town, Cape Town, South Africa.
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Źródło :
Immunology [Immunology] 2021 Nov; Vol. 164 (3), pp. 524-540. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells/*immunology
Mycobacterium tuberculosis/*immunology
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Receptors, Tumor Necrosis Factor, Type II/*metabolism
Tuberculosis/*immunology
Animals ; Dendritic Cells/metabolism ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Mice, Transgenic ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Receptors, Tumor Necrosis Factor, Type II/genetics ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł :
Impaired function and delayed regeneration of dendritic cells in COVID-19.
Autorzy :
Winheim E; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Rinke L; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Lutz K; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Reischer A; Department of Medicine III, University Hospital, LMU Munich; Munich, Germany.; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich; Munich, Germany.
Leutbecher A; Department of Medicine III, University Hospital, LMU Munich; Munich, Germany.; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich; Munich, Germany.
Wolfram L; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Rausch L; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Kranich J; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Wratil PR; Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine & Gene Center, Virology, National Reference Center for Retroviruses, LMU Munich; Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany.
Huber JE; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Baumjohann D; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.; Medical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Rothenfusser S; Division of Clinical Pharmacology, University Hospital, LMU Munich; Munich, Germany.; Unit Clinical Pharmacology (EKLiP), Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany.
Schubert B; Institute of Computational Biology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Mathematics, Technical University of Munich, Garching, Germany.
Hilgendorff A; Institute for Lung Biology and Disease and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.; Center for Comprehensive Developmental Care (CDeCLMU), Dr. Von Haunersche Children's Hospital, University Hospital LMU Munich; Munich, Germany.
Hellmuth JC; Department of Medicine III, University Hospital, LMU Munich; Munich, Germany.; COVID-19 Registry of the LMU Munich (CORKUM), University Hospital, LMU Munich; Munich, Germany.
Scherer C; COVID-19 Registry of the LMU Munich (CORKUM), University Hospital, LMU Munich; Munich, Germany.; Department of Medicine I, University Hospital, LMU Munich; Munich, Germany.
Muenchhoff M; Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine & Gene Center, Virology, National Reference Center for Retroviruses, LMU Munich; Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany.; COVID-19 Registry of the LMU Munich (CORKUM), University Hospital, LMU Munich; Munich, Germany.
von Bergwelt-Baildon M; Department of Medicine III, University Hospital, LMU Munich; Munich, Germany.; COVID-19 Registry of the LMU Munich (CORKUM), University Hospital, LMU Munich; Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ); Heidelberg, Germany.
Stark K; COVID-19 Registry of the LMU Munich (CORKUM), University Hospital, LMU Munich; Munich, Germany.; Department of Medicine I, University Hospital, LMU Munich; Munich, Germany.
Straub T; Core Facility Bioinformatics, Biomedical Center, LMU Munich; Munich, Germany.
Brocker T; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
Keppler OT; Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine & Gene Center, Virology, National Reference Center for Retroviruses, LMU Munich; Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany.
Subklewe M; Department of Medicine III, University Hospital, LMU Munich; Munich, Germany.; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich; Munich, Germany.
Krug AB; Institute for Immunology, Biomedical Center (BMC), Faculty of Medicine, LMU Munich; Munich, Germany.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Oct 06; Vol. 17 (10), pp. e1009742. Date of Electronic Publication: 2021 Oct 06 (Print Publication: 2021).
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
COVID-19/*immunology
Dendritic Cells/*immunology
Regeneration/*immunology
SARS-CoV-2/*immunology
Adult ; Antigens, CD/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/pathology ; COVID-19/pathology ; Dendritic Cells/pathology ; Female ; Humans ; Male ; Middle Aged ; Monocytes/immunology ; Monocytes/pathology ; Programmed Cell Death 1 Receptor/immunology
Czasopismo naukowe
Tytuł :
Optimal CD8 T-cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses.
Autorzy :
Dimonte S; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Gimeno-Brias S; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Marsden M; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Chapman L; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Sabberwal P; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Clement M; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Humphreys IR; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
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Źródło :
Immunology [Immunology] 2021 Oct; Vol. 164 (2), pp. 279-291. Date of Electronic Publication: 2021 Jun 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Cytomegalovirus/*immunology
Cytomegalovirus Infections/*immunology
Dendritic Cells/*immunology
Immunologic Memory/*immunology
Skin/*immunology
Virus Replication/*immunology
Animals ; Antigens, Viral/immunology ; CD8-Positive T-Lymphocytes/virology ; Cytomegalovirus Infections/virology ; Dendritic Cells/virology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Skin/virology
Czasopismo naukowe
Tytuł :
Melatonin administration provokes the activity of dendritic reticular cells in the seminal vesicle of Soay ram during the non-breeding season.
Autorzy :
Abd-Elhafeez HH; Department of Anatomy, Embryology and Histology, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt.
Hassan AHS; Department of Anatomy, Embryology and Histology, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt.
Hussein MT; Department of Anatomy, Embryology and Histology, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jan 13; Vol. 11 (1), pp. 872. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells, Follicular/*metabolism
Melatonin/*pharmacology
Seminal Vesicles/*metabolism
Animals ; Dendritic Cells/drug effects ; Dendritic Cells/metabolism ; Dendritic Cells, Follicular/drug effects ; Lymphocytes/immunology ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Melatonin/metabolism ; Seminal Vesicles/drug effects ; Sheep ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; Telocytes/drug effects ; Telocytes/immunology
Czasopismo naukowe
Tytuł :
Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure.
Autorzy :
Salei N; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Ji X; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Pakalniškytė D; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Kuentzel V; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Rambichler S; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
Li N; Division of Nephrology, The Seventh Affiliated Hospital, Sun Yat-sen University, 518107 Shenzhen, China.; Division of Nephrology, Medizinische Klinik und Poliklinik IV, University Hospital, Ludwig-Maximilians-Universität in Munich, 80366 Munich, Germany.
Moser M; Institute of Experimental Hematology, School of Medicine, Technische Universität München, D-81675 Munich, Germany.
Steiger K; Institute of Pathology, School of Medicine, Technische Universität München, D-81675 München, Germany.
Buch T; Institute of Laboratory Animal Science, University of Zürich, 8956 Zürich, Switzerland.
Anders HJ; Division of Nephrology, Medizinische Klinik und Poliklinik IV, University Hospital, Ludwig-Maximilians-Universität in Munich, 80366 Munich, Germany.
Schraml BU; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany; .; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, 82152 Planegg-Martinsried, Germany.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acute Kidney Injury/*prevention & control
Dendritic Cells/*immunology
Heparin-binding EGF-like Growth Factor/*metabolism
Macrophages/*immunology
Monocytes/*immunology
Phagocytes/*metabolism
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/metabolism ; Acute Kidney Injury/pathology ; Animals ; Antineoplastic Agents/toxicity ; Cisplatin/toxicity ; Dendritic Cells/metabolism ; Dendritic Cells/pathology ; Female ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/metabolism ; Monocytes/pathology ; Phagocytes/cytology ; Receptors, IgG
Czasopismo naukowe
Tytuł :
Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells.
Autorzy :
Laustsen A; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
van der Sluis RM; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Aarhus Institute of Advanced Studies, Aarhus University, Aarhus, Denmark.
Gris-Oliver A; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Hernández SS; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Cemalovic E; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Centre of Molecular Inflammation Research, Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Medicine, St. Olav's University Hospital, Trondheim, Norway.
Tang HQ; Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Pedersen LH; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Uldbjerg N; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Jakobsen MR; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Bak RO; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Aarhus Institute of Advanced Studies, Aarhus University, Aarhus, Denmark.
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Źródło :
ELife [Elife] 2021 Sep 02; Vol. 10. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells*/cytology
Dendritic Cells*/drug effects
Hematopoietic Stem Cells*/cytology
Hematopoietic Stem Cells*/drug effects
Ascorbic Acid/*pharmacology
Cell Culture Techniques/*methods
Cell Differentiation/*drug effects
Cells, Cultured ; Culture Media/chemistry ; Humans ; Immunotherapy
Czasopismo naukowe
Tytuł :
The cytokine milieu compromises functional capacity of tumor-infiltrating plasmacytoid dendritic cells in HPV-negative but not in HPV-positive HNSCC.
Autorzy :
Koucký V; Sotio, Prague, Czech Republic. .; Department of Otorhinolaryngology and Head and Neck Surgery, First Medical Faculty, Motol University Hospital, Prague, Czech Republic. .
Hladíková K; Sotio, Prague, Czech Republic.
Táborská E; Sotio, Prague, Czech Republic.
Bouček J; Department of Otorhinolaryngology and Head and Neck Surgery, First Medical Faculty, Motol University Hospital, Prague, Czech Republic.
Grega M; Department of Pathology and Molecular Medicine, Second Medical Faculty, Motol University Hospital, Prague, Czech Republic.
Špíšek R; Sotio, Prague, Czech Republic.
Fialová A; Sotio, Prague, Czech Republic. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Sep; Vol. 70 (9), pp. 2545-2557. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article
MeSH Terms :
Tumor Microenvironment*/immunology
Cytokines/*metabolism
Dendritic Cells/*immunology
Dendritic Cells/*metabolism
Papillomavirus Infections/*complications
Papillomavirus Infections/*virology
Squamous Cell Carcinoma of Head and Neck/*etiology
Squamous Cell Carcinoma of Head and Neck/*metabolism
Biomarkers ; Case-Control Studies ; Cell Transformation, Viral ; Dendritic Cells/pathology ; Disease Susceptibility ; Gene Expression ; Humans ; Interferon-alpha/immunology ; Interferon-alpha/metabolism ; Squamous Cell Carcinoma of Head and Neck/pathology ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism
Czasopismo naukowe

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