- Tytuł:
- Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma.
- Autorzy:
- Źródło:
- Cell death and differentiation [Cell Death Differ] 2002 Aug; Vol. 9 (8), pp. 842-55.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Cell Differentiation/*physiology
Keratinocytes/*metabolism
Membrane Proteins/*metabolism
NF-kappa B/*metabolism
Proteins/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolismSkin /*growth & development
Transcription Factors/*metabolism
Adult ; Calcium-Binding Proteins ; Cell Compartmentation/physiology ; Cell Differentiation/drug effects ; Cell Size/drug effects ; Cell Size/physiology ; Cells, Cultured ; Epidermal Cells ; Epidermis/metabolism ; Humans ; I-kappa B Kinase ; Immunohistochemistry ; Infant, Newborn ; Intercellular Signaling Peptides and Proteins ; Jagged-1 Protein ; Keratinocytes/cytology ; Keratinocytes/drug effects ; Male ; Peptide Fragments/pharmacology ; Protein Precursors/metabolism ; Protein Serine-Threonine Kinases/drug effects ; Protein Serine-Threonine Kinases/metabolism ; Proteins/pharmacology ; Proto-Oncogene Proteins/metabolism ; Receptor, Notch1 ; Receptor, Notch2 ; Receptor, Notch4 ; Receptors, Cell Surface/metabolism ; Receptors, Notch ; Serrate-Jagged Proteins ; Signal Transduction/drug effects ; Signal Transduction/physiology ;Skin /cytology ;Skin /metabolism ; Up-Regulation/drug effects ; Up-Regulation/physiology
Czasopismo naukowe