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Tytuł :
Uptake of fluorescent D- and L-glucose analogues, 2-NBDG and 2-NBDLG, into human osteosarcoma U2OS cells in a phloretin-inhibitable manner.
Autorzy :
Ogawa T; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Sasaki A; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Ono K; Department of Physiology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Ohshika S; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Ishibashi Y; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Yamada K; Department of Physiology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan. .
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Źródło :
Human cell [Hum Cell] 2021 Mar; Vol. 34 (2), pp. 634-643. Date of Electronic Publication: 2021 Jan 17.
Typ publikacji :
Journal Article
MeSH Terms :
4-Chloro-7-nitrobenzofurazan/*analogs & derivatives
Bone Neoplasms/*metabolism
Deoxyglucose/*analogs & derivatives
Glucose/*metabolism
Osteosarcoma/*metabolism
Phloretin/*pharmacology
4-Chloro-7-nitrobenzofurazan/metabolism ; Animals ; Cytochalasin B/pharmacology ; Deoxyglucose/metabolism ; Depression, Chemical ; Glucose Transport Proteins, Facilitative/antagonists & inhibitors ; Glucose Transport Proteins, Facilitative/metabolism ; Humans ; Insulinoma/metabolism ; Isomerism ; Mice ; Pancreatic Neoplasms/metabolism ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Homoharringtonine inhibits fibroblasts proliferation, extracellular matrix production and reduces surgery-induced knee arthrofibrosis via PI3K/AKT/mTOR pathway-mediated apoptosis.
Autorzy :
Sun Y; Department of Orthopedics, Clinical medical college of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, 225001, Jiangsu, China.; School of Medicine, Nanjing University, Nanjing, 210008, Jiangsu, China.
Dai J; Dalian medical university, Dalian, 116044, Liaoning, China.
Jiao R; Department of Orthopedics, Clinical medical college of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, 225001, Jiangsu, China.
Jiang Q; School of Medicine, Nanjing University, Nanjing, 210008, Jiangsu, China. .
Wang J; Department of Orthopedics, Clinical medical college of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, 225001, Jiangsu, China. .
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Źródło :
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jan 06; Vol. 16 (1), pp. 9. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Apoptosis/*genetics
Cell Proliferation/*drug effects
Extracellular Matrix/*metabolism
Fibroblasts/*metabolism
Fibroblasts/*physiology
Homoharringtonine/*pharmacology
Knee Joint/*pathology
Phosphatidylinositol 3-Kinases/*metabolism
Postoperative Complications/*pathology
Proto-Oncogene Proteins c-akt/*metabolism
Signal Transduction/*genetics
Signal Transduction/*physiology
TOR Serine-Threonine Kinases/*metabolism
Cell Line ; Depression, Chemical ; Fibrosis/prevention & control ; Humans ; Postoperative Complications/prevention & control
Czasopismo naukowe
Tytuł :
Chamaecyparis obtusa Essential Oil Inhibits House Dust Mite Induced Nasal Epithelial Cell Activation and Immune Responses.
Autorzy :
Shin SH; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu.
Ye MK; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu.
Chae MH; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu.
Lee DW; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu.
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Źródło :
Journal of oleo science [J Oleo Sci] 2021; Vol. 70 (3), pp. 431-438.
Typ publikacji :
Journal Article
MeSH Terms :
Immunologic Factors*
Chamaecyparis/*chemistry
Epithelial Cells/*drug effects
Epithelial Cells/*immunology
Immunity/*drug effects
Nasal Mucosa/*cytology
Oils, Volatile/*pharmacology
Pyroglyphidae/*immunology
Adult ; Animals ; Cells, Cultured ; Cytokines/metabolism ; Depression, Chemical ; Epithelial Cells/metabolism ; Female ; Humans ; Male ; Middle Aged ; Oils, Volatile/chemistry ; Oils, Volatile/isolation & purification ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Kaolin Reduces ABA Biosynthesis Through the Inhibition of Neoxanthin Synthesis in Grapevines Under Water Deficit.
Autorzy :
Frioni T; Department of Sustainable Crop Production, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, Italy.
Tombesi S; Department of Sustainable Crop Production, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, Italy.
Sabbatini P; Department of Horticulture, Michigan State University, 1066 Bogue Street, East Lansing, MI 48824, USA.
Squeri C; Department of Sustainable Crop Production, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, Italy.
Lavado Rodas N; CICYTEX (Junta de Extremadura), Finca La Orden, Ctra. A-V, km 372, Guadajira, 06187 Badajoz, Spain.
Palliotti A; Department of Agricultural, Food and Environmental Sciences, Università degli Studi di Perugia, Borgo XX Giugno 74, 06121 Perugia, Italy.
Poni S; Department of Sustainable Crop Production, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 13; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article
MeSH Terms :
Abscisic Acid/*metabolism
Kaolin/*pharmacology
Plant Leaves/*drug effects
Plant Transpiration/*drug effects
Vitis/*drug effects
Xanthophylls/*metabolism
Carbon Dioxide/metabolism ; Depression, Chemical ; Droughts ; Photosynthesis ; Plant Leaves/metabolism ; Plant Leaves/radiation effects ; Stress, Physiological ; Vitis/metabolism
Czasopismo naukowe
Tytuł :
D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats.
Autorzy :
Navarro JA; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.; Facultad de Medicina, Universidad de Málaga, 29010 Málaga, Spain.
Decara J; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Medina-Vera D; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.; Facultad de Ciencias, Universidad de Málaga, 29010 Málaga, Spain.
Tovar R; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.; Facultad de Medicina, Universidad de Málaga, 29010 Málaga, Spain.
Suarez J; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Pavón J; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Serrano A; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Vida M; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Gutierrez-Adan A; Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, 28040 Madrid, Spain.
Sanjuan C; Euronutra S.L. Calle Johannes Kepler, 3, 29590 Málaga, Spain.
Baixeras E; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Málaga, 29010 Málaga, Spain.
Fonseca FR; Laboratorio de Medicina Regenerativa, Instituto IBIMA de Málaga, Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
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Źródło :
Nutrients [Nutrients] 2020 Jul 08; Vol. 12 (7). Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Fabaceae/*chemistry
Ghrelin/*blood
Inositol/*analogs & derivatives
Insulin Secretion/*drug effects
Liver/*metabolism
Administration, Oral ; Animals ; Depression, Chemical ; Ghrelin/metabolism ; Glucagon/metabolism ; Glycogen/metabolism ; Glycogen Synthase Kinase 3/metabolism ; Glycolysis ; Inositol/administration & dosage ; Inositol/isolation & purification ; Inositol/pharmacokinetics ; Inositol/pharmacology ; Male ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Pyruvate Kinase/metabolism ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Circular RNA atlas in osteoclast differentiation with and without alendronate treatment.
Autorzy :
Lin J; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China.
Ma S; Obstetrics and Gynecology Department, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, Zhangzhou, China.
Zhu C; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China.
Chen C; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China.
Lin W; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China.
Lin C; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China.
Huang G; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China. .
Ding Z; Center for Orthopedics, Affiliated Southeast Hospital of Xiamen University/909th Hospital of People's Liberation Army, 269 Zhanghua Middle Road, Zhangzhou, 363000, Fujian, China. .
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Źródło :
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2020 Jul 01; Vol. 15 (1), pp. 240. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
Alendronate/*pharmacology
Bone Density Conservation Agents/*pharmacology
Cell Differentiation/*drug effects
Cell Differentiation/*genetics
Osteoclasts/*physiology
RNA, Circular/*genetics
RNA, Circular/*physiology
Depression, Chemical ; Humans ; Macrophage Colony-Stimulating Factor/pharmacology ; RANK Ligand/pharmacology ; RNA, Circular/metabolism ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Anti-Obesity Effects of Tanshinone I from Salvia miltiorrhiza Bunge in Mice Fed a High-Fat Diet through Inhibition of Early Adipogenesis.
Autorzy :
Jung DY; Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.
Kim JH; Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.
Jung MH; Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.
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Źródło :
Nutrients [Nutrients] 2020 Apr 27; Vol. 12 (5). Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Obesity Agents*
Phytotherapy*
Abietanes/*pharmacology
Adipogenesis/*drug effects
Diet, High-Fat/*adverse effects
Obesity/*drug therapy
Salvia miltiorrhiza/*chemistry
3T3 Cells ; AMP-Activated Protein Kinases/metabolism ; Abietanes/administration & dosage ; Abietanes/isolation & purification ; Adipocytes/metabolism ; Adipocytes/physiology ; Adipogenesis/genetics ; Administration, Oral ; Animals ; CCAAT-Enhancer-Binding Protein-beta/metabolism ; Cell Cycle/genetics ; Depression, Chemical ; Glucose/metabolism ; Mice ; Obesity/etiology ; Obesity/metabolism ; Phosphorylation ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
In Vitro Effect of Methanolic Extract of Argemone mexicana against Trichomonas vaginalis.
Autorzy :
Elizondo-Luevano JH; Department of Chemistry, College of Biological Sciences, Autonomous University of Nuevo León, Nuevo León 66455, México.
Verde-Star J; Department of Chemistry, College of Biological Sciences, Autonomous University of Nuevo León, Nuevo León 66455, México.
González-Horta A; Department of Chemistry, College of Biological Sciences, Autonomous University of Nuevo León, Nuevo León 66455, México.
Castro-Ríos R; Department of Analytic Chemistry, College of Medicine, Autonomous University of Nuevo León, Nuevo León 64460, México.
Hernández-García ME; Northeast Biomedical Research Center, Instituto Mexicano del Seguro Social, Nuevo León 64720, México.
Chávez-Montes A; Department of Chemistry, College of Biological Sciences, Autonomous University of Nuevo León, Nuevo León 66455, México.
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Źródło :
The Korean journal of parasitology [Korean J Parasitol] 2020 Apr; Vol. 58 (2), pp. 135-145. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
Plant Extracts/*pharmacology
Trichomonas vaginalis/*drug effects
Trichomonas vaginalis/*growth & development
Antineoplastic Combined Chemotherapy Protocols ; Bacterial Vaccines ; Cyclophosphamide ; Depression, Chemical ; Dose-Response Relationship, Drug ; Doxorubicin ; Fluorouracil ; In Vitro Techniques ; Leucovorin ; Methanol ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Plant Stems/chemistry ; Quinones ; Sterols ; Triterpenes
SCR Protocol :
CALF protocol
Czasopismo naukowe
Tytuł :
Inhibitory effect of retinoic acid receptor agonists on in vitro chondrogenic differentiation.
Autorzy :
Sumitani Y; Department of Orthodontics, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
Uchibe K; Department of Oral Morphology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan. .
Yoshida K; Department of Oral Healthcare Promotion, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima, 770-8504, Japan.
Weng Y; Department of Oral Morphology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
Guo J; Department of Oral Morphology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
Yuan H; Department of Oral Morphology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
Ikegame M; Department of Oral Morphology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
Kamioka H; Department of Orthodontics, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
Okamura H; Department of Oral Morphology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8525, Japan.
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Źródło :
Anatomical science international [Anat Sci Int] 2020 Mar; Vol. 95 (2), pp. 202-208. Date of Electronic Publication: 2019 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation/*drug effects
Chondrocytes/*physiology
Receptors, Retinoic Acid/*agonists
Vitamin A/*pharmacology
Vitamin A/*physiology
Animals ; Bone Development/drug effects ; Cell Differentiation/genetics ; Cells, Cultured ; Chondrogenesis ; Depression, Chemical ; Gene Expression ; Mice ; Osteogenesis/drug effects ; Receptors, Retinoic Acid/physiology ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
4-Hydroxybenzaldehyde Restricts the Intracellular Growth of Toxoplasma gondii by Inducing SIRT1-Mediated Autophagy in Macrophages.
Autorzy :
Lee J; Department of Infection Biology and Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Choi JW; Department of Infection Biology and Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Han HY; Department of Infection Biology and Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kim WS; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.
Song HY; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.
Byun EB; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.
Byun EH; Department of Food Science and Technology, Kongju National University, Yesan 32439, Korea.
Lee YH; Department of Infection Biology and Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Yuk JM; Department of Infection Biology and Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
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Źródło :
The Korean journal of parasitology [Korean J Parasitol] 2020 Feb; Vol. 58 (1), pp. 7-14. Date of Electronic Publication: 2020 Feb 29.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy*
Sirtuin 1*
Benzaldehydes/*pharmacology
Macrophages/*physiology
Toxoplasma/*growth & development
Animals ; Cells, Cultured ; Depression, Chemical ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
The inhibitory effect of somatostatin on gastric motility in Suncus murinus.
Autorzy :
Sekiya H; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, 255 Shimo-ohkubo, Sakuraku, Saitama 338-8570, Japan.
Yokota N; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, 255 Shimo-ohkubo, Sakuraku, Saitama 338-8570, Japan.
Takemi S; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, 255 Shimo-ohkubo, Sakuraku, Saitama 338-8570, Japan.
Nakayama K; Research Center of Neurology, Discovery and Research, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan.
Okada H; Discovery Technology Research Laboratories, Discovery and Research, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan.
Sakai T; Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama 338-8570, Japan.
Sakata I; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, 255 Shimo-ohkubo, Sakuraku, Saitama 338-8570, Japan.; Area of Life-NanoBio, Division of Strategy Research, Graduate School of Science and Engineering, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama 338-8570, Japan.
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Źródło :
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi [J Smooth Muscle Res] 2020; Vol. 56 (0), pp. 69-81.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Motility/*drug effects
Somatostatin/*pharmacology
Animals ; Depression, Chemical ; Female ; In Vitro Techniques ; Male ; Motilin/pharmacology ; Muscle Contraction/drug effects ; Muscle, Smooth/drug effects ; Myoelectric Complex, Migrating/drug effects ; Postprandial Period ; Shrews ; Somatostatin/physiology ; Somatostatin/therapeutic use
Czasopismo naukowe
Tytuł :
A Mixed-ligand Zn(II)-based Coordination Polymer for Selectively Detect 2,4,6-Trinitrophenol (TNP) and Treatment Effect on Periodontal Diseases via Inhibition Effect on P. gingivalis Growth.
Autorzy :
Zhao JG; Department of Stomatology, The Fourth Hospital of Hebei Medical University.
Yang KC; Department of Stomatology, The Fourth Hospital of Hebei Medical University.
Yang L; Department of Stomatology, The Second Hospital of Shijiazhuang.
Chen YP; Department of Stomatology, The Fourth Hospital of Hebei Medical University.
Sun R; Department of Stomatology, The Fourth Hospital of Hebei Medical University.
Guo JX; Department of Stomatology, The Fourth Hospital of Hebei Medical University.
Li DQ; Department of Stomatology, China General Hospital.
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Źródło :
Journal of oleo science [J Oleo Sci] 2020; Vol. 69 (2), pp. 115-122.
Typ publikacji :
Journal Article
MeSH Terms :
Periodontal Diseases/*drug therapy
Porphyromonas gingivalis/*growth & development
Trinitrobenzenes/*chemistry
Trinitrobenzenes/*therapeutic use
Zinc Compounds/*chemistry
Zinc Compounds/*therapeutic use
Depression, Chemical ; Humans ; Ligands ; Periodontal Diseases/microbiology ; Polymers ; Trinitrobenzenes/pharmacology ; Zinc Compounds/pharmacology
Czasopismo naukowe
Tytuł :
Bisphenol A and rotenone induce S-nitrosylation of protein disulfide isomerase (PDI) and inhibit neurite outgrowth of primary cultured cells of the rat hippocampus and PC12 cells.
Autorzy :
Kobayashi Y; Department of Biomedical Chemistry, School of Science and Technology, Kwansei Gakuin University.
Oguro A; Department of Biomedical Chemistry, School of Science and Technology, Kwansei Gakuin University.; Program of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University.
Yagi E; Department of Biomedical Chemistry, School of Science and Technology, Kwansei Gakuin University.
Mitani A; Department of Human-System Interaction, School of Science and Technology, Kwansei Gakuin University.
Kudoh SN; Department of Human-System Interaction, School of Science and Technology, Kwansei Gakuin University.
Imaoka S; Department of Biomedical Chemistry, School of Science and Technology, Kwansei Gakuin University.
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Źródło :
The Journal of toxicological sciences [J Toxicol Sci] 2020; Vol. 45 (12), pp. 783-794.
Typ publikacji :
Journal Article
MeSH Terms :
Neurotoxins*
Benzhydryl Compounds/*toxicity
Brain/*metabolism
Hippocampus/*cytology
Neuronal Outgrowth/*drug effects
Phenols/*toxicity
Protein Disulfide-Isomerases/*metabolism
Rotenone/*toxicity
Animals ; Depression, Chemical ; Male ; Nitric Oxide/physiology ; Oxidation-Reduction/drug effects ; PC12 Cells ; Rats ; Rats, Sprague-Dawley ; Ribonucleases/metabolism ; omega-N-Methylarginine/pharmacology
Czasopismo naukowe
Tytuł :
Sulforaphane inhibits the activation of hepatic stellate cell by miRNA-423-5p targeting suppressor of fused.
Autorzy :
Feng MH; The Third Affiliated Hospital Of Guangzhou University of Chinese Medicine, Guangzhou, 510515, China.
Li JW; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Sun HT; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
He SQ; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Pang J; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. .
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Źródło :
Human cell [Hum Cell] 2019 Oct; Vol. 32 (4), pp. 403-410. Date of Electronic Publication: 2019 Jul 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Survival/*drug effects
Cell Survival/*genetics
Hepatic Stellate Cells/*physiology
Isothiocyanates/*pharmacology
Liver Cirrhosis/*etiology
Liver Cirrhosis/*genetics
MicroRNAs/*metabolism
Cell Line ; Depression, Chemical ; Down-Regulation/drug effects ; Humans ; Isothiocyanates/therapeutic use ; Liver Cirrhosis/drug therapy ; MicroRNAs/genetics ; Molecular Targeted Therapy
Czasopismo naukowe
Tytuł :
Human Cardiac Ventricular-Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two-Tiered Assay for Inotropic Responses.
Autorzy :
Keung W; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Shatin, Hong Kong.; Dr. Li Dak-Sum Research Centre, The University of Hong Kong, Pokfulam, Hong Kong.
Chan PKW; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Shatin, Hong Kong.
Backeris PC; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York,, USA.
Lee EK; Novoheart, Vancouver, British Columbia, Canada.
Wong N; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Shatin, Hong Kong.
Wong AOT; Novoheart, Vancouver, British Columbia, Canada.
Wong GKY; Novoheart, Vancouver, British Columbia, Canada.
Chan CWY; Novoheart, Vancouver, British Columbia, Canada.
Fermini B; Global Safety Pharmacology, Pfizer Worldwide Research and Development, Groton, Connecticut, USA.
Costa KD; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York,, USA.; Novoheart, Vancouver, British Columbia, Canada.
Li RA; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Shatin, Hong Kong.; Dr. Li Dak-Sum Research Centre, The University of Hong Kong, Pokfulam, Hong Kong.; Novoheart, Vancouver, British Columbia, Canada.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2019 Aug; Vol. 106 (2), pp. 402-414. Date of Electronic Publication: 2019 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Myocytes, Cardiac*/drug effects
Myocytes, Cardiac*/physiology
Organoids*/drug effects
Organoids*/physiology
Cardiotonic Agents/*pharmacology
Myocardial Contraction/*drug effects
Cardiovascular Agents/pharmacology ; Cells, Cultured ; Depression, Chemical ; Drug Discovery/methods ; Drug Evaluation, Preclinical/methods ; Humans ; Induced Pluripotent Stem Cells ; Models, Cardiovascular ; Stimulation, Chemical ; Tissue Engineering/methods
Czasopismo naukowe
Tytuł :
Characterization of binding of antipsychotics to muscarinic receptors using mouse cerebral cortex.
Autorzy :
Obara K; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan. Electronic address: .
Horiguchi S; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
Shimada T; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
Ikarashi T; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
Yamaki F; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
Matsuo K; Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
Yoshio T; Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
Tanaka Y; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba, 274-8510, Japan.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2019 Jun; Vol. 140 (2), pp. 197-200. Date of Electronic Publication: 2019 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antipsychotic Agents/*metabolism
Antipsychotic Agents/*pharmacology
Cerebral Cortex/*metabolism
Cholinergic Antagonists/*metabolism
Cholinesterase Inhibitors/*metabolism
Receptors, Muscarinic/*metabolism
Scopolamine/*metabolism
Animals ; Chlorpromazine/pharmacology ; Depression, Chemical ; Drug Interactions ; Male ; Methotrimeprazine/pharmacology ; Mice, Inbred Strains ; Prochlorperazine/pharmacology ; Protein Binding
Czasopismo naukowe
Tytuł :
Quercetin suppresses the tumorigenesis of oral squamous cell carcinoma by regulating microRNA-22/WNT1/β-catenin axis.
Autorzy :
Zhang C; Department of Stomatology, Yuhuangding Hospital, Yantai, 264000, China.
Hao Y; Department of Stomatology, Yuhuangding Hospital, Yantai, 264000, China.
Sun Y; Department of Periodontology, Yantai Stomatological Hospital, Yantai, 264000, China.
Liu P; Department of Stomatology, Affiliated Hospital of Jining Medical University, Jining, 272029, China. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2019 Jun; Vol. 140 (2), pp. 128-136. Date of Electronic Publication: 2019 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenesis/*drug effects
Carcinogenesis/*genetics
Carcinoma, Squamous Cell/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
Mouth Neoplasms/*genetics
Quercetin/*pharmacology
Signal Transduction/*drug effects
Animals ; Antineoplastic Agents, Phytogenic ; Apoptosis/drug effects ; Cell Survival/drug effects ; Depression, Chemical ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Mouth Neoplasms/pathology ; Signal Transduction/genetics ; Tumor Cells, Cultured ; Wnt1 Protein/genetics ; Wnt1 Protein/metabolism ; beta Catenin/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human laboratory study.
Autorzy :
Pirtle JL; Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America.
Hickman MD; Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America.
Boinpelly VC; Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America.
Surineni K; Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America; Department of Psychiatry, University of Kansas School of Medicine, Wichita, KS 67226, United States of America.
Thakur HK; Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America.
Grasing KW; Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America; Division of Clinical Pharmacology, Department of Medicine, University of Kansas School of Medicine, Kansas City, KS 66160, United States of America. Electronic address: .
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Źródło :
Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2019 May; Vol. 180, pp. 52-59. Date of Electronic Publication: 2019 Feb 24.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Benzazepines/*pharmacology
Cocaine/*pharmacology
Cocaine-Related Disorders/*drug therapy
Heart Rate/*drug effects
Serotonin 5-HT2 Receptor Agonists/*pharmacology
Vasoconstrictor Agents/*pharmacology
Administration, Intravenous ; Administration, Oral ; Adult ; Benzazepines/administration & dosage ; Benzazepines/adverse effects ; Blood Pressure/drug effects ; Cocaine/administration & dosage ; Cocaine/adverse effects ; Craving/drug effects ; Cross-Over Studies ; Depression, Chemical ; Double-Blind Method ; Drug Therapy, Combination ; Humans ; Male ; Middle Aged ; Self Administration ; Serotonin 5-HT2 Receptor Agonists/administration & dosage ; Serotonin 5-HT2 Receptor Agonists/adverse effects ; Stimulation, Chemical ; Treatment Outcome ; Vasoconstrictor Agents/administration & dosage ; Vasoconstrictor Agents/adverse effects
Czasopismo naukowe
Tytuł :
Synthesis and Characterization of a Novel Glycolipid with Glucosylglycerate as a Hydrophile Showing Protective Effects on Heat-induced Protein Denaturation.
Autorzy :
Sato S; Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST).
Kishimoto A; Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science.
Kitamoto D; Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST).
Takahashi Y; Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science.; Present address: New Industry Creation Hatchery Center (NICHe), Tohoku University.
Kondo Y; Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science.
Habe H; Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST).; Present address: Environmental Management Research Institute, National Institute of Advanced Industrial Science and Technology (AIST).
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Źródło :
Journal of oleo science [J Oleo Sci] 2019 May 01; Vol. 68 (5), pp. 493-499. Date of Electronic Publication: 2019 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Surface-Active Agents*
Glycolipids/*chemical synthesis
Glycolipids/*pharmacology
Hot Temperature/*adverse effects
Protein Denaturation/*drug effects
Amines/chemistry ; Catalysis ; Depression, Chemical ; Dose-Response Relationship, Drug ; Glucosyltransferases/chemistry ; Glyceric Acids/chemistry ; Hydrophobic and Hydrophilic Interactions ; Morpholines/chemistry ; Organic Chemistry Phenomena ; Solubility ; Solvents ; Sucrose/chemistry ; Surface Tension ; Water
Czasopismo naukowe
Tytuł :
Sevoflurane prevents hypoxia/reoxygenation-induced cardiomyocyte apoptosis by inhibiting PI3KC3-mediated autophagy.
Autorzy :
Lu Y; Department of Anesthesiology, Changzhou No.2 People's Hospital, The Affiliated Hospital of Nanjing Medical University, No. 29 Xinglong Road, Changzhou, 213000, Jiangsu, China.
Bu M; Department of Anesthesiology, Changzhou No.2 People's Hospital, The Affiliated Hospital of Nanjing Medical University, No. 29 Xinglong Road, Changzhou, 213000, Jiangsu, China. .
Yun H; Department of Anesthesiology, Changzhou No.2 People's Hospital, The Affiliated Hospital of Nanjing Medical University, No. 29 Xinglong Road, Changzhou, 213000, Jiangsu, China.
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Źródło :
Human cell [Hum Cell] 2019 Apr; Vol. 32 (2), pp. 150-159. Date of Electronic Publication: 2018 Dec 12.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents*
Apoptosis/*drug effects
Autophagy/*drug effects
Autophagy/*genetics
Class III Phosphatidylinositol 3-Kinases/*metabolism
Myocardial Reperfusion Injury/*pathology
Myocardial Reperfusion Injury/*prevention & control
Myocytes, Cardiac/*pathology
Sevoflurane/*pharmacology
Sevoflurane/*therapeutic use
Beclin-1/metabolism ; Cells, Cultured ; Depression, Chemical ; Humans ; Induced Pluripotent Stem Cells ; Phosphorylation/drug effects
Czasopismo naukowe

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