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    Wyświetlanie 1-6 z 6
    Tytuł:
    The efficacy and safety of pinocembrin in a sheep model of bleomycin-induced pulmonary fibrosis.
    Autorzy:
    Derseh HB; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.
    Goodger JQD; School of Biosciences, University of Melbourne, Parkville, Victoria, Australia.
    Scheerlinck JY; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.
    Samuel CS; Cardiovascular Disease Program, Monash Biomedicine Discovery Institute and Department of Pharmacology, Monash University, Clayton, Victoria, Australia.
    Woodrow IE; School of Ecosystem and Forest Sciences, University of Melbourne, Parkville, Victoria, Australia.
    Palombo EA; Department of Chemistry and Biotechnology, Swinburne University of Technology, Hawthorn, Victoria, Australia.
    Cumming A; Gretals Australia Pty Ltd, Mornington, Victoria, Australia.
    Snibson K; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.
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    Źródło:
    PloS one [PLoS One] 2021 Dec 02; Vol. 16 (12), pp. e0260719. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antifibrotic Agents/*therapeutic use
    Flavanones/*therapeutic use
    Pulmonary Fibrosis/*drug therapy
    Animals ; Bleomycin/toxicity ; Bronchoalveolar Lavage Fluid/chemistry ; Bronchoalveolar Lavage Fluid/immunology ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/metabolism ; Disease Models, Animal ; Eucalyptus/chemistry ; Eucalyptus/metabolism ; Flavanones/isolation & purification ; Lung/pathology ; Neutrophils/cytology ; Neutrophils/metabolism ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/pathology ; Respiratory Function Tests ; Severity of Illness Index ; Sheep ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Evaluation of microRNA expression in a sheep model for lung fibrosis.
    Autorzy:
    Perera UE; School of Veterinary Science, The University of Melbourne, Parkville, VIC, Australia. .
    Derseh HB; School of Veterinary Science, The University of Melbourne, Parkville, VIC, Australia.
    Dewage SNV; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
    Stent A; School of Veterinary Science, The University of Melbourne, Werribee, VIC, Australia.
    Wijayarathna R; Centre for Reproductive Health, Hudson Institute of Medical Research, Australia and Monash University, Clayton, VIC, Australia.
    Snibson KJ; School of Veterinary Science, The University of Melbourne, Parkville, VIC, Australia. .
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    Źródło:
    BMC genomics [BMC Genomics] 2021 Nov 17; Vol. 22 (1), pp. 827. Date of Electronic Publication: 2021 Nov 17.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Idiopathic Pulmonary Fibrosis*/chemically induced
    Idiopathic Pulmonary Fibrosis*/genetics
    MicroRNAs*/genetics
    Animals ; Bleomycin/toxicity ; Genetic Techniques ; Humans ; Lung ; Mice ; Sheep
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mucosal immune responses in the trachea after chronic infection with Mycoplasma gallisepticum in unvaccinated and vaccinated mature chickens.
    Autorzy:
    Kulappu Arachchige SN; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Wawegama NK; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Coppo MJC; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Derseh HB; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Vaz PK; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Kanci Condello A; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Omotainse OS; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, Victoria, Australia.
    Noormohammadi AH; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, Victoria, Australia.
    Browning GF; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
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    Źródło:
    Cellular microbiology [Cell Microbiol] 2021 Nov; Vol. 23 (11), pp. e13383. Date of Electronic Publication: 2021 Aug 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mycoplasma Infections*/veterinary
    Mycoplasma gallisepticum*/genetics
    Poultry Diseases*
    Animals ; Bacterial Vaccines ; Chickens ; Immunity, Mucosal ; Persistent Infection ; Trachea
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Small airway remodeling in a sheep model of bleomycin-induced pulmonary fibrosis.
    Autorzy:
    Derseh HB; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Australia.
    Dewage SNV; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Australia.
    Perera UE; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Australia.
    Koumoundouros E; Department of Biomedical Engineering, The University of Melbourne, Parkville, Australia.
    Pagel CN; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Australia.
    Organ L; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK.
    Snibson KJ; Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Australia.
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    Źródło:
    Experimental lung research [Exp Lung Res] 2020 Dec; Vol. 46 (10), pp. 409-419. Date of Electronic Publication: 2020 Oct 14.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Bleomycin*
    Pulmonary Fibrosis*/chemically induced
    Pulmonary Fibrosis*/pathology
    Airway Remodeling ; Animals ; Disease Models, Animal ; Humans ; Lung/pathology ; Sheep
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    K Ca 3.1 channel blockade attenuates microvascular remodelling in a large animal model of bleomycin-induced pulmonary fibrosis.
    Autorzy:
    Derseh HB; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia. .
    Dewage SNV; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Perera KUE; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Pagel CN; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Koumoundouros E; Department of Electrical and Electronic Engineering, The University of Melbourne, Parkville, Victoria, Australia.
    Organ L; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK.
    Snibson KJ; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
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    Źródło:
    Scientific reports [Sci Rep] 2019 Dec 27; Vol. 9 (1), pp. 19893. Date of Electronic Publication: 2019 Dec 27.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Bleomycin/*adverse effects
    Intermediate-Conductance Calcium-Activated Potassium Channels/*metabolism
    Lung/*blood supply
    Pulmonary Fibrosis/*metabolism
    Vascular Remodeling/*drug effects
    Acetamides/pharmacology ; Animals ; Bleomycin/pharmacology ; Cell Proliferation/drug effects ; Disease Models, Animal ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Female ; Gene Expression Regulation/drug effects ; Intermediate-Conductance Calcium-Activated Potassium Channels/antagonists & inhibitors ; Lung/pathology ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/drug therapy ; Pulmonary Fibrosis/pathology ; Sheep ; Trityl Compounds/pharmacology ; Vascular Endothelial Growth Factor A/biosynthesis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The efficacy of pirfenidone in a sheep model of pulmonary fibrosis.
    Autorzy:
    Dewage SNV; Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville, Australia.
    Organ L; Nottingham Respiratory Research Unit, University of Nottingham, Nottingham, UK.
    Koumoundouros E; Department of Electrical and Electronic Engineering, The University of Melbourne, Parkville, Australia.
    Derseh HB; Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville, Australia.
    Perera KUE; Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville, Australia.
    Samuel CS; Department of Pharmacology, Monash University, Clayton, Australia.
    Stent AW; Faculty of Veterinary Science and Agricultural Science, The University of Melbourne, Werribee, Australia.
    Snibson KJ; Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville, Australia.
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    Źródło:
    Experimental lung research [Exp Lung Res] 2019 Nov - Dec; Vol. 45 (9-10), pp. 310-322. Date of Electronic Publication: 2019 Nov 25.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Idiopathic Pulmonary Fibrosis/*drug therapy
    Lung/*drug effects
    Pyridones/*pharmacology
    Animals ; Bleomycin/pharmacology ; Disease Models, Animal ; Extracellular Matrix/drug effects ; Female ; Indoles/pharmacology ; Myofibroblasts/drug effects ; Sheep
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-6 z 6

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