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Wyszukujesz frazę ""Desmin"" wg kryterium: Temat


Tytuł :
Desmin Interacts Directly with Mitochondria.
Autorzy :
Dayal AA; Institute of Protein Research of Russian Academy of Sciences, Vavilova st., 34, 119334 Moscow, Russia.
Medvedeva NV; Institute of Protein Research of Russian Academy of Sciences, Vavilova st., 34, 119334 Moscow, Russia.
Nekrasova TM; Institute of Protein Research of Russian Academy of Sciences, Vavilova st., 34, 119334 Moscow, Russia.
Duhalin SD; Institute of Protein Research of Russian Academy of Sciences, Vavilova st., 34, 119334 Moscow, Russia.
Surin AK; Institute of Protein Research of Russian Academy of Sciences, Vavilova st., 34, 119334 Moscow, Russia.; Pushchino Branch, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospekt Nauki 6, Pushchino, 142290 Moscow Region, Russia.
Minin AA; Institute of Protein Research of Russian Academy of Sciences, Vavilova st., 34, 119334 Moscow, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 30; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Cysteine Proteases/*metabolism
Desmin/*metabolism
Intermediate Filaments/*metabolism
Mitochondria/*metabolism
Vimentin/*metabolism
Animals ; Cells, Cultured ; Desmin/genetics ; Humans ; Rats ; Vimentin/genetics
Czasopismo naukowe
Tytuł :
Coordinated alpha-crystallin B phosphorylation and desmin expression indicate adaptation and deadaptation to resistance exercise-induced loading in human skeletal muscle.
Autorzy :
Jacko D; Department for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.; Olympic Base Center, North Rhine-Westphalia/Rhineland, Cologne, Germany.
Bersiner K; Department for Biosciences of Sports, Institute for Sports Sciences, University of Hildesheim, Hildesheim, Germany.
Schulz O; Department for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.
Przyklenk A; Department for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.
Spahiu F; Department for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.
Höhfeld J; Institute for Cell Biology, University of Bonn, Bonn, Germany.
Bloch W; Department for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.
Gehlert S; Department for Molecular and Cellular Sports Medicine, Institute for Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.; Department for Biosciences of Sports, Institute for Sports Sciences, University of Hildesheim, Hildesheim, Germany.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Aug 01; Vol. 319 (2), pp. C300-C312. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptation, Physiological/*genetics
Desmin/*genetics
Muscle, Skeletal/*metabolism
alpha-Crystallin B Chain/*genetics
Adult ; Cytoskeleton/genetics ; Cytoskeleton/metabolism ; Desmin/metabolism ; Gene Expression Regulation/genetics ; Humans ; Male ; Muscle Contraction/physiology ; Muscle, Skeletal/physiology ; Phosphorylation/genetics ; Resistance Training/adverse effects ; Young Adult ; alpha-Crystallin B Chain/metabolism
Czasopismo naukowe
Tytuł :
Growing Old Too Early: Skeletal Muscle Single Fiber Biomechanics in Ageing R349P Desmin Knock-in Mice Using the MyoRobot Technology.
Autorzy :
Pollmann C; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Bavaria, Germany.
Haug M; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Bavaria, Germany.; Graduate School in Advanced Optical Technologies, Paul-Gordan-Str. 6, 91052 Erlangen, Bavaria, Germany.; School of Medical Sciences, University of New South Wales, Wallace Wurth Building, 18 High St, Sydney, NSW 2052, Australia.
Reischl B; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Bavaria, Germany.
Prölß G; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Bavaria, Germany.
Pöschel T; Institute of Multi Scale Simulation of Particulate Systems, Friedrich-Alexander-University Erlangen-Nürnberg, Nägelbachstr. 49b, 91052 Erlangen, Bavaria, Germany.
Rupitsch SJ; Institute of Sensor Technology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3/5, 91052 Erlangen, Bavaria, Germany.
Clemen CS; German Aerospace Center (DLR), Institute of Aerospace Medicine, Linder Höhe, 51147 Cologne, North Rhine-Westphalia, Germany.; Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Bavaria, Germany.; Insitute of Vegetative Physiology, Medical Faculty, University of Cologne, Center of Physiology and Pathophysiology, Robert-Koch-Street 39, 50931 Cologne, North Rhine-Westphalia, Germany.
Schröder R; Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Bavaria, Germany.; Muscle Research Center Erlangen (MURCE), Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Bavaria, Germany.
Friedrich O; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Bavaria, Germany.; Graduate School in Advanced Optical Technologies, Paul-Gordan-Str. 6, 91052 Erlangen, Bavaria, Germany.; School of Medical Sciences, University of New South Wales, Wallace Wurth Building, 18 High St, Sydney, NSW 2052, Australia.; Muscle Research Center Erlangen (MURCE), Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Bavaria, Germany.; Victor Chang Cardiac Research Institute, Lowy Packer Building, 405 Liverpool St, Sydney, NSW 2010, Australia.; Optical Imaging Centre Erlangen OICE, Cauerstr. 3, 91058 Erlangen, Bavaria, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 31; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*genetics
Desmin/*genetics
Muscle Fibers, Skeletal/*chemistry
Myofibrils/*genetics
Aging/physiology ; Animals ; Biomechanical Phenomena ; Calcium/metabolism ; Cytoskeleton/chemistry ; Cytoskeleton/genetics ; Desmin/chemistry ; Disease Models, Animal ; Gene Knock-In Techniques ; Humans ; Intermediate Filaments/chemistry ; Intermediate Filaments/genetics ; Mice ; Muscle Contraction/genetics ; Muscle Contraction/physiology ; Muscle Fibers, Skeletal/physiology ; Mutation/genetics ; Myofibrils/chemistry
Czasopismo naukowe
Tytuł :
Heterozygous desmin gene ( DES ) mutation contributes to familial dilated cardiomyopathy.
Autorzy :
Huang YS; Research Ward, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xing YL; Department of Geriatrics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Li HW; Department of Geriatrics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.; Department of Cardiology, Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.; Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease, Capital Medical University, Beijing, China.
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Źródło :
The Journal of international medical research [J Int Med Res] 2021 Apr; Vol. 49 (4), pp. 3000605211006598.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Cardiomyopathy, Dilated*/diagnostic imaging
Cardiomyopathy, Dilated*/genetics
Adult ; Aged ; Desmin/genetics ; Female ; Humans ; Male ; Middle Aged ; Mutation ; Pedigree ; Stroke Volume ; Ventricular Function, Left
SCR Disease Name :
Familial dilated cardiomyopathy
Czasopismo naukowe
Tytuł :
Desmin mutations result in mitochondrial dysfunction regardless of their aggregation properties.
Autorzy :
Smolina N; Almazov National Medical Research Centre, Saint Petersburg, Russia; Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden. Electronic address: .
Khudiakov A; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Knyazeva A; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Zlotina A; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Sukhareva K; Almazov National Medical Research Centre, Saint Petersburg, Russia; University of Verona, Verona, Italy.
Kondratov K; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Gogvadze V; Faculty of medicine, Lomonosov Moscow State University, Moscow, Russia; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.
Zhivotovsky B; Faculty of medicine, Lomonosov Moscow State University, Moscow, Russia; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.
Sejersen T; Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.
Kostareva A; Almazov National Medical Research Centre, Saint Petersburg, Russia; Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Jun 01; Vol. 1866 (6), pp. 165745. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Desmin/*genetics
Mitochondria/*genetics
Muscular Diseases/*genetics
Protein Aggregates/*genetics
DNA, Mitochondrial/genetics ; Desmin/classification ; Gene Expression Regulation/genetics ; Humans ; Intermediate Filaments/metabolism ; Intermediate Filaments/pathology ; Mitochondria/metabolism ; Mitochondria/pathology ; Muscle Cells/metabolism ; Muscle Cells/pathology ; Muscle Fibers, Skeletal/metabolism ; Muscle Fibers, Skeletal/pathology ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Muscular Diseases/metabolism ; Muscular Diseases/pathology ; Mutation/genetics ; Phenotype
Czasopismo naukowe
Tytuł :
The role of desmin alterations in mechanical electrical feedback in heart failure.
Autorzy :
Chen L; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Wang L; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li X; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Wang C; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Hong M; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li Y; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Cao J; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China. Electronic address: .
Fu L; The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Jan 15; Vol. 241, pp. 117119. Date of Electronic Publication: 2019 Nov 30.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium/*metabolism
Desmin/*metabolism
Heart Failure/*etiology
NF-kappa B/*metabolism
Animals ; Calpain/metabolism ; Cells, Cultured ; Desmin/genetics ; Dipeptides/pharmacology ; Disease Models, Animal ; Electrocardiography ; Feedback, Physiological ; Gene Knockdown Techniques ; Male ; Myocytes, Cardiac ; NF-kappa B/genetics ; Rats, Sprague-Dawley ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Tachycardia, Ventricular/complications ; Tachycardia, Ventricular/physiopathology
Czasopismo naukowe
Tytuł :
Ketogenic Diet Enhances the Cholesterol Accumulation in Liver and Augments the Severity of CCl 4 and TAA-Induced Liver Fibrosis in Mice.
Autorzy :
Liao YJ; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Wang YH; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Wu CY; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Hsu FY; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Chien CY; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Lee YC; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 13; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
3-Hydroxybutyric Acid/*pharmacology
Acetoacetates/*pharmacology
Cholesterol/*biosynthesis
Diet, Ketogenic/*adverse effects
Liver/*drug effects
Liver Cirrhosis/*metabolism
3-Hydroxybutyric Acid/biosynthesis ; Acetoacetates/metabolism ; Actins/genetics ; Actins/metabolism ; Animals ; Becaplermin/pharmacology ; Carbon Tetrachloride/administration & dosage ; Catalase/genetics ; Catalase/metabolism ; Cell Proliferation/drug effects ; Cholesterol/blood ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Cytochrome P-450 CYP1A2/genetics ; Cytochrome P-450 CYP1A2/metabolism ; Desmin/genetics ; Desmin/metabolism ; Disease Progression ; Gene Expression Regulation/drug effects ; Hepatic Stellate Cells/cytology ; Hepatic Stellate Cells/drug effects ; Hepatic Stellate Cells/metabolism ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/genetics ; Liver Cirrhosis/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Primary Cell Culture ; Severity of Illness Index ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism ; Thioacetamide/administration & dosage ; Transforming Growth Factor beta/biosynthesis ; Transforming Growth Factor beta/pharmacology
Czasopismo naukowe
Tytuł :
Effect of medium voltage electrical stimulation and prior ageing on beef shear force during superchilled storage.
Autorzy :
Ji X; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China.
Luo X; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China; Jiangsu Synergetic Innovation Center of Meat Production and Processing Quality and Safety Control, Nanjing, Jiangsu 210000, PR China.
Zhu L; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China.
Mao Y; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China.
Lu X; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China.
Chen X; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China.
Hopkins DL; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; NSW Department of Primary Industries, Centre for Red Meat and Sheep Development, PO Box 129, Cowra, NSW 2794, Australia.
Zhang Y; Lab of Beef Processing and Quality Control, College of Food Science and Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; National R&D Center for Beef Processing Technology, Tai'an, Shandong 271018, PR China. Electronic address: .
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Źródło :
Meat science [Meat Sci] 2021 Feb; Vol. 172, pp. 108320. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Shear Strength*
Electric Stimulation/*methods
Red Meat/*analysis
Animals ; Cattle ; Desmin/analysis ; Food Storage ; Myofibrils ; Refrigeration ; Time Factors
Czasopismo naukowe
Tytuł :
Restrictive Cardiomyopathy is Caused by a Novel Homozygous Desmin ( DES ) Mutation p.Y122H Leading to a Severe Filament Assembly Defect.
Autorzy :
Brodehl A; Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum. Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
Pour Hakimi SA; Otto-von-Guericke University, Magdeburg, Universitätsplatz 2, D-39106 Magdeburg, Germany.
Stanasiuk C; Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum. Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
Ratnavadivel S; Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum. Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
Hendig D; Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
Gaertner A; Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum. Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
Gerull B; Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, AB T2N4Z6, Canada.; Comprehensive Heart Failure Center and Department of Internal Medicine I, University Hospital Würzburg, D-97080 Würzburg, Germany.
Gummert J; Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum. Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.; Department of Cardio-Thoracic Surgery, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany.
Paluszkiewicz L; Department of Cardio-Thoracic Surgery, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany.
Milting H; Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum. Georgstrasse 11, D-32545 Bad Oeynhausen, Germany.
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Źródło :
Genes [Genes (Basel)] 2019 Nov 11; Vol. 10 (11). Date of Electronic Publication: 2019 Nov 11.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiomyopathy, Restrictive/*genetics
Desmin/*genetics
Intermediate Filaments/*metabolism
Adult ; Cardiomyopathy, Restrictive/diagnosis ; Cardiomyopathy, Restrictive/pathology ; Consanguinity ; Desmin/metabolism ; Echocardiography ; Genetic Counseling ; Genetic Testing ; Homozygote ; Humans ; Intermediate Filaments/genetics ; Iran ; Male ; Mutation, Missense ; Pedigree ; Protein Domains/genetics ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Alterations of redox dynamics and desmin post-translational modifications in skeletal muscle models of desminopathies.
Autorzy :
Delort F; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Segard BD; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Hakibilen C; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Bourgois-Rocha F; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Cabet E; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Vicart P; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Huang ME; Institut Curie, PSL Research University, CNRS UMR3348, Université Paris-Sud, Université Paris-Saclay, Orsay, 91405, France.
Clary G; Inserm U1016, Institut Cochin, CNRS UMR8104, Université Paris-Descartes, Sorbonne Paris Cité, Plateforme Protéomique 3P5, Paris, France.
Lilienbaum A; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France.
Agbulut O; Sorbonne Université, Institut de Biologie Paris-Seine (IBPS), CNRS UMR 8256, Inserm ERL U1164, Biological Adaptation and Ageing, 75005, Paris, France.
Batonnet-Pichon S; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, F-75013, Paris, France. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2019 Oct 15; Vol. 383 (2), pp. 111539. Date of Electronic Publication: 2019 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Desmin*/genetics
Desmin*/metabolism
Oxidation-Reduction*
Cardiomyopathies/*genetics
Cardiomyopathies/*metabolism
Muscle, Skeletal/*metabolism
Muscular Dystrophies/*genetics
Muscular Dystrophies/*metabolism
Amino Acid Substitution/genetics ; Animals ; Antioxidants/metabolism ; Cardiomyopathies/pathology ; Cells, Cultured ; Disease Models, Animal ; Homeostasis/genetics ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Muscle Proteins/metabolism ; Muscle, Skeletal/pathology ; Muscular Dystrophies/pathology ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Oxidative Stress/genetics ; Protein Processing, Post-Translational/genetics
SCR Disease Name :
Myopathy, Myofibrillar, Desmin-Related
Czasopismo naukowe
Tytuł :
Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2.
Autorzy :
Javed E; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Thangavel C; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA.
Frara N; Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Singh J; Department of Medicine, Division of Gastroenterology & Hepatology, Thomas Jefferson University, Philadelphia, PA, USA.
Mohanty I; Department of Medicine, Division of Gastroenterology & Hepatology, Thomas Jefferson University, Philadelphia, PA, USA.
Hypolite J; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Birbe R; Department of Pathology and Laboratory Medicine, Cooper University Health Care, Camden, NJ, USA.
Braverman AS; Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Den RB; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA.
Rattan S; Department of Medicine, Division of Gastroenterology & Hepatology, Thomas Jefferson University, Philadelphia, PA, USA.
Zderic SA; Department of Urology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Deshpande DA; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Penn RB; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Ruggieri MR Sr; Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Chacko S; Division of Urology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathobiology, University of Pennsylvania, Philadelphia, PA, USA.
Boopathi E; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.; Division of Urology, University of Pennsylvania, Philadelphia, PA, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Feb; Vol. 34 (2), pp. 2126-2146. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
MAP Kinase Signaling System*
Muscle Contraction*
Desmin/*biosynthesis
Mitogen-Activated Protein Kinase 9/*metabolism
Muscle, Smooth/*metabolism
Urinary Bladder/*metabolism
Vimentin/*biosynthesis
Animals ; Desmin/genetics ; Mice ; Mice, Knockout ; Mitogen-Activated Protein Kinase 9/genetics ; Muscle, Smooth/cytology ; Urinary Bladder/cytology ; Vimentin/genetics
Czasopismo naukowe
Tytuł :
A Novel DES L115F Mutation Identified by Whole Exome Sequencing is Associated with Inherited Cardiac Conduction Disease.
Autorzy :
Hsu LA; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Ko YS; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Yeh YH; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Chang CJ; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Chan YH; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Kuo CT; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Tsai HY; Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan 33305, Taiwan.
Chang GJ; Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan 33305, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Dec 10; Vol. 20 (24). Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation, Missense*
Cardiac Conduction System Disease/*genetics
Desmin/*genetics
Whole Exome Sequencing/*methods
Adult ; Aged ; Animals ; Asian Continental Ancestry Group/genetics ; Desmin/chemistry ; Female ; HeLa Cells ; Homozygote ; Humans ; Male ; Mice ; Middle Aged ; Pedigree ; Protein Conformation
Czasopismo naukowe
Tytuł :
Primary cutaneous carcinosarcoma: clinical, histological, and immunohistochemical analysis of eight cases.
Autorzy :
García-Souto F; Department of Dermatology, Hospital Universitario de Valme, Seville, Spain.
Pereyra-Rodriguez JJ; Department of Dermatology, Hospital Universitario Virgen del Rocío, Seville, Spain.
Cabrera-Perez R; Department of Pathology, Hospital Universitario Virgen del Rocío, Seville, Spain.
Durán-Romero AJ; Department of Dermatology, Hospital Universitario Virgen del Rocío, Seville, Spain.
Escudero-Ordoñez J; Department of Dermatology, Hospital Universitario de Valme, Seville, Spain.
Conejo-Mir J; Department of Dermatology, Hospital Universitario Virgen del Rocío, Seville, Spain.
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Źródło :
International journal of dermatology [Int J Dermatol] 2021 Jan; Vol. 60 (1), pp. 93-98. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinosarcoma/*metabolism
Carcinosarcoma/*pathology
Neoplasm Recurrence, Local/*pathology
Skin Neoplasms/*metabolism
Skin Neoplasms/*pathology
Actins/metabolism ; Adult ; Aged, 80 and over ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Carcinosarcoma/secondary ; Carcinosarcoma/surgery ; Desmin/metabolism ; Female ; Humans ; Immunohistochemistry ; Keratin-1/metabolism ; Keratin-3/metabolism ; Male ; Matrix Attachment Region Binding Proteins/metabolism ; Membrane Proteins/metabolism ; Middle Aged ; Myogenin/metabolism ; Neprilysin/metabolism ; Retrospective Studies ; Skin Neoplasms/surgery ; Transcription Factors/metabolism ; alpha 1-Antitrypsin/metabolism
Czasopismo naukowe
Tytuł :
Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers.
Autorzy :
Kedia N; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130.
Arhzaouy K; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
Pittman SK; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
Sun Y; Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO 63130.; University College London Institute of Prion Diseases/Medical Research Council Prion Unit, University College London, London W1W 7FF, United Kingdom.
Batchelor M; University College London Institute of Prion Diseases/Medical Research Council Prion Unit, University College London, London W1W 7FF, United Kingdom.
Weihl CC; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110; .
Bieschke J; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130; .; University College London Institute of Prion Diseases/Medical Research Council Prion Unit, University College London, London W1W 7FF, United Kingdom.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Aug 20; Vol. 116 (34), pp. 16835-16840. Date of Electronic Publication: 2019 Aug 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Aggregates*/drug effects
Amyloid/*metabolism
Desmin/*metabolism
Muscle Fibers, Skeletal/*metabolism
Animals ; Catechin/analogs & derivatives ; Catechin/pharmacology ; Desmin/chemistry ; Desmin/genetics ; Desmin/ultrastructure ; Humans ; Mice ; Muscle Fibers, Skeletal/drug effects ; Mutation
Czasopismo naukowe
Tytuł :
Geigerin-induced disorganization of desmin, an intermediate filament of the cytoskeleton, in a murine myoblast cell line (C2C12).
Autorzy :
Botha CJ; Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X 04, Onderstepoort, 0110, South Africa. Electronic address: .
Venter EA; Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X 04, Onderstepoort, 0110, South Africa.
Ferreira GCH; Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X 04, Onderstepoort, 0110, South Africa.
Phaswane RM; Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X 04, Onderstepoort, 0110, South Africa.
Clift SJ; Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X 04, Onderstepoort, 0110, South Africa.
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2019 Sep; Vol. 167, pp. 162-167. Date of Electronic Publication: 2019 Jun 14.
Typ publikacji :
Journal Article
MeSH Terms :
Cytoskeleton/*drug effects
Desmin/*drug effects
Sesquiterpenes/*toxicity
Animals ; Cell Line ; Cytoskeleton/ultrastructure ; Desmin/ultrastructure ; Immunohistochemistry ; Intermediate Filament Proteins/drug effects ; Intermediate Filament Proteins/ultrastructure ; Mice ; Myoblasts/drug effects
Czasopismo naukowe
Tytuł :
Noncompaction cardiomyopathy is caused by a novel in-frame desmin (DES) deletion mutation within the 1A coiled-coil rod segment leading to a severe filament assembly defect.
Autorzy :
Marakhonov AV; Laboratory of Genetic Epidemiology, Research Centre for Medical Genetics (RCMG), Moscow, Russia.; School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia.
Brodehl A; Erich and Hanna Klessmann Institute, Heart and Diabetes Centre NRW, University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany.
Myasnikov RP; Department of Clinical Cardiology and Molecular Genetics, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Sparber PA; School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia.
Kiseleva AV; Laboratory of Molecular Genetics, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Kulikova OV; Department of Clinical Cardiology and Molecular Genetics, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Meshkov AN; Department of Molecular and Cellular Genetics, Pirogov Russian National Research Medical University, Moscow, Russia.; Laboratory of Molecular Genetics, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Zharikova AA; M.V. Lomonosov Moscow State University, Moscow, Russia.; Laboratory of Molecular Genetics, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Koretsky SN; Department of Fundamental and Applied Aspects of Obesity, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Kharlap MS; Cardiac Arrhythmias Department, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Stanasiuk C; Erich and Hanna Klessmann Institute, Heart and Diabetes Centre NRW, University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany.
Mershina EA; M.V. Lomonosov Moscow State University, Moscow, Russia.; Radiology Department, Lomonosov Moscow State University Medical Research and Educational Center, Moscow, Russia.
Sinitsyn VE; M.V. Lomonosov Moscow State University, Moscow, Russia.; Radiology Department, Lomonosov Moscow State University Medical Research and Educational Center, Moscow, Russia.
Shevchenko AO; Department of Critical Care Translational Medicine, V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
Mozheyko NP; Pathology Department, V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
Drapkina OM; Department of Fundamental and Applied Aspects of Obesity, Federal State Institution National Center for Preventive Medicine, Moscow, Russia.
Boytsov SA; National Medical Research Center of Cardiology, Moscow, Russia.
Milting H; Erich and Hanna Klessmann Institute, Heart and Diabetes Centre NRW, University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany.
Skoblov MY; Laboratory of Functional Genomics, Research Centre for Medical Genetics (RCMG), Moscow, Russia, Russia.; School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia.
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Źródło :
Human mutation [Hum Mutat] 2019 Jun; Vol. 40 (6), pp. 734-741. Date of Electronic Publication: 2019 Apr 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Sequence Deletion*
Cardiomyopathy, Dilated/*genetics
Desmin/*chemistry
Desmin/*genetics
Adult ; Cardiomyopathy, Dilated/metabolism ; Cytoplasm/metabolism ; Desmin/metabolism ; Female ; Heart Defects, Congenital ; Humans ; Male ; Models, Molecular ; Pedigree ; Protein Domains ; Proteolysis ; Sarcomeres/metabolism
Czasopismo naukowe
Tytuł :
Dysfunctional Mitochondrial Dynamic and Oxidative Phosphorylation Precedes Cardiac Dysfunction in R120G-αB-Crystallin-Induced Desmin-Related Cardiomyopathy.
Autorzy :
Alam S; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Abdullah CS; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Aishwarya R; Department of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Shreveport LA.
Morshed M; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Nitu SS; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Miriyala S; Department of Cellular Biology and Anatomy Louisiana State University Health Sciences Center Shreveport LA.
Panchatcharam M; Department of Cellular Biology and Anatomy Louisiana State University Health Sciences Center Shreveport LA.
Kevil CG; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.; Department of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Shreveport LA.; Department of Cellular Biology and Anatomy Louisiana State University Health Sciences Center Shreveport LA.
Orr AW; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.; Department of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Shreveport LA.; Department of Cellular Biology and Anatomy Louisiana State University Health Sciences Center Shreveport LA.
Bhuiyan MS; Department of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.; Department of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Shreveport LA.
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2020 Dec; Vol. 9 (23), pp. e017195. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Oxidative Phosphorylation*
Cardiomyopathies/*etiology
Cardiomyopathies/*pathology
Mitochondrial Dynamics/*physiology
Animals ; Cardiomyopathies/metabolism ; Desmin ; Disease Models, Animal ; Mice ; Mice, Transgenic ; alpha-Crystallin B Chain
Czasopismo naukowe
Tytuł :
The protective role of desmin in duchenne muscular dystrophy: Therapeutic insights.
Autorzy :
Chaffer TJ; Department of Biology, Acadia University, Wolfville, Nova Scotia, Canada.; Meakins-Christie Laboratories and Translational Research in Respiratory Diseases Program, Research Institute of the McGill University Health Centre, Canada.
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Źródło :
The Journal of physiology [J Physiol] 2020 Nov; Vol. 598 (21), pp. 4759-4760. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Muscular Dystrophy, Duchenne*/therapy
Animals ; Desmin ; Fatigue ; Mice ; Mice, Inbred mdx ; Muscles
Czasopismo naukowe
Tytuł :
Role of calpains in promoting desmin filaments depolymerization and muscle atrophy.
Autorzy :
Cohen S; Technion Israel Institute of Technology, Israel. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Oct; Vol. 1867 (10), pp. 118788. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Polymerization*
Calpain/*metabolism
Desmin/*metabolism
Muscular Atrophy/*metabolism
Animals ; Humans ; Myofibrils/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł :
Myosin heavy chain isoform and metabolic profile differ in beef steaks varying in tenderness.
Autorzy :
Dang DS; Department of Nutrition, Dietetics and Food Sciences, Utah State University, Logan, UT 84322, United States.
Buhler JF; Department of Nutrition, Dietetics and Food Sciences, Utah State University, Logan, UT 84322, United States.
Thornton KJ; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, United States.
Legako JF; Department of Animal and Food Sciences, Texas Tech University, Lubbock, TX 79409, United States.
Matarneh SK; Department of Nutrition, Dietetics and Food Sciences, Utah State University, Logan, UT 84322, United States. Electronic address: .
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Źródło :
Meat science [Meat Sci] 2020 Dec; Vol. 170, pp. 108266. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle Fibers, Skeletal/*metabolism
Myosin Heavy Chains/*analysis
Red Meat/*analysis
Animals ; Calcium Channels ; Cattle ; Desmin/metabolism ; Muscle, Skeletal/enzymology ; Muscle, Skeletal/metabolism ; Proteolysis ; Troponin T/metabolism
Czasopismo naukowe

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