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Wyszukujesz frazę ""Deubiquitinating Enzymes"" wg kryterium: Temat


Tytuł:
Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma.
Autorzy:
Jin S; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tsunematsu T; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Horiguchi T; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Mouri Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Shao W; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Miyoshi K; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Hagita H; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Sarubo M; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Fujiwara N; Department of Oral Healthcare Management, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Qi G; Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China.
Ishimaru N; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Kudo Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 Dec; Vol. 12 (24), pp. 22156-22169. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Head and Neck Neoplasms*/genetics
Squamous Cell Carcinoma of Head and Neck*/genetics
Deubiquitinating Enzymes*/metabolism
YAP-Signaling Proteins*/metabolism
Humans ; Cell Line, Tumor ; Ubiquitin Thiolesterase
Czasopismo naukowe
Tytuł:
OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6.
Autorzy:
Zhao Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Department of Neurological Rehabilitation, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Ruan J; Department of Pathology, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
Li Z; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Su X; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Chen K; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Lin Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Cai Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Wang P; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Liu B; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Department of Neurological Rehabilitation, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Schlüter D; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.
Liang G; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.; School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, China.
Wang X; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Department of Neurological Rehabilitation, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1385.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenesis*
Cell Transformation, Neoplastic*
Deubiquitinating Enzymes*/metabolism
CCN Intercellular Signaling Proteins*/metabolism
Humans ; Blotting, Western ; Cytoplasm ; Proteasome Endopeptidase Complex
Czasopismo naukowe
Tytuł:
Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma.
Autorzy:
Zhang, Xingming (AUTHOR)
Geng, Lou (AUTHOR)
Tang, Yi (AUTHOR)
Wang, Yingying (AUTHOR)
Zhang, Youping (AUTHOR)
Zhu, Chujiao (AUTHOR)
Lei, Hu (AUTHOR)
Xu, Hanzhang (AUTHOR)
Zhu, Qi (AUTHOR)
Wu, Yingli (AUTHOR)
Gu, Wenli (AUTHOR)
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Źródło:
Journal of Translational Medicine. 2/22/2024, Vol. 22 Issue 1, p1-18. 18p.
Czasopismo naukowe
Tytuł:
USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis.
Autorzy:
Zhang, Nannan (AUTHOR)
Zhang, Hui (AUTHOR)
Yang, Xiaobing (AUTHOR)
Xue, Qiang (AUTHOR)
Wang, Quhui (AUTHOR)
Chang, Renan (AUTHOR)
Zhu, Lirong (AUTHOR)
Chen, Zhong (AUTHOR)
Liu, Xiancheng (AUTHOR)
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Źródło:
BMC Cancer. 2/21/2024, Vol. 24 Issue 1, p1-15. 15p.
Czasopismo naukowe
Tytuł:
USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity.
Autorzy:
Kuang, Xianghong (AUTHOR)
Salinger, Andrew (AUTHOR)
Benavides, Fernando (AUTHOR)
Muller, William J. (AUTHOR)
Dent, Sharon Y. R. (AUTHOR)
Koutelou, Evangelia (AUTHOR)
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Źródło:
PLoS ONE. 1/18/2024, Vol. 19 Issue 1, p1-19. 19p.
Czasopismo naukowe
Tytuł:
USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer.
Autorzy:
Tu, Rongfu (AUTHOR)
Kang, Ye (AUTHOR)
Pan, Yiwen (AUTHOR)
Da, Yanyan (AUTHOR)
Ren, Doudou (AUTHOR)
Zhang, Ru (AUTHOR)
Cai, Zeqiong (AUTHOR)
Liu, Yijia (AUTHOR)
Xu, Jiao (AUTHOR)
Ma, Junpeng (AUTHOR)
Zhou, Zhiyong (AUTHOR)
Yin, Shupeng (AUTHOR)
Li, Xiaozhuang (AUTHOR)
Zhang, Peng (AUTHOR)
Zhang, Qi (AUTHOR)
Wang, Jingchao (AUTHOR)
Lu, Xinlan (AUTHOR)
Zhang, Chengsheng (AUTHOR)
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Źródło:
Cancer Cell International. 1/17/2024, Vol. 24 Issue 1, p1-14. 14p.
Czasopismo naukowe
Tytuł:
Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases.
Autorzy:
Wang, Shaowei (AUTHOR)
Tian, Xuezhang (AUTHOR)
Zhou, Yaru (AUTHOR)
Xie, Jun (AUTHOR)
Gao, Ming (AUTHOR)
Zhong, Yunhong (AUTHOR)
Zhang, Chuchu (AUTHOR)
Yu, Keying (AUTHOR)
Bai, Lei (AUTHOR)
Qin, Qingsong (AUTHOR)
Zhong, Bo (AUTHOR)
Lin, Dandan (AUTHOR)
Feng, Pinghui (AUTHOR)
Lan, Ke (AUTHOR)
Zhang, Junjie (AUTHOR)
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Źródło:
PLoS Pathogens. 1/12/2024, Vol. 20 Issue 1, p1-25. 25p.
Czasopismo naukowe
Tytuł:
A novel missense variant in OTUD5 causes X‐linked multiple congenital anomalies‐neurodevelopmental syndrome.
Autorzy:
Tian, Weifang (AUTHOR)
Li, Haiyu (AUTHOR)
Li, Ying (AUTHOR)
Guo, Jing (AUTHOR)
Wang, Handuo (AUTHOR)
Yang, Bo (AUTHOR)
Li, Pengyun (AUTHOR)
Cui, Xueyin (AUTHOR)
Liu, Ling (AUTHOR)
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Źródło:
Molecular Genetics & Genomic Medicine. Jan2024, Vol. 12 Issue 1, p1-10. 10p.
Czasopismo naukowe
Tytuł:
Deubiquitinating Enzyme Inhibitors Block Chikungunya Virus Replication.
Autorzy:
López LS; Grupo de Virología, Universidad El Bosque, Bogotá 110121, Colombia.
Calvo EP; Grupo de Virología, Universidad El Bosque, Bogotá 110121, Colombia.
Castellanos JE; Grupo de Virología, Universidad El Bosque, Bogotá 110121, Colombia.
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Źródło:
Viruses [Viruses] 2023 Feb 09; Vol. 15 (2). Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chikungunya Fever*/drug therapy
Chikungunya virus*/drug effects
Deubiquitinating Enzymes*/antagonists & inhibitors
Enzyme Inhibitors*/pharmacology
Enzyme Inhibitors*/therapeutic use
Virus Replication*/drug effects
Humans ; HEK293 Cells ; RNA, Viral
Czasopismo naukowe
Tytuł:
Deubiquitinase USP17 Regulates Osteoblast Differentiation by Increasing Osterix Protein Stability.
Autorzy:
Kim MJ; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Chonnam National University, Gwangju 61186, Republic of Korea.
Piao M; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Chonnam National University, Gwangju 61186, Republic of Korea.
Li Y; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Chonnam National University, Gwangju 61186, Republic of Korea.
Lee SH; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Chonnam National University, Gwangju 61186, Republic of Korea.
Lee KY; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Chonnam National University, Gwangju 61186, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 17; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Osteogenesis*/genetics
Osteoblasts*/metabolism
Sp7 Transcription Factor/genetics ; Sp7 Transcription Factor/metabolism ; Cell Differentiation/genetics ; Protein Stability ; Deubiquitinating Enzymes/genetics ; Deubiquitinating Enzymes/metabolism
Czasopismo naukowe
Tytuł:
Structure-function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains.
Autorzy:
Radmall KS; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.
Shukla PK; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.
Leng AM; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.
Chandrasekharan MB; Department of Radiation Oncology and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA. .; Huntsman Cancer Institute, University of Utah School of Medicine, 2000, Circle of Hope, Room 3715, Salt Lake City, UT, 84112, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 04; Vol. 13 (1), pp. 16731. Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Histones*/genetics
Histones*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Proliferating Cell Nuclear Antigen/genetics ; Proliferating Cell Nuclear Antigen/metabolism ; Ubiquitination ; Ubiquitin/genetics ; Ubiquitin/metabolism ; Deubiquitinating Enzymes/genetics ; Deubiquitinating Enzymes/metabolism ; Ubiquitin-Conjugating Enzymes/metabolism ; Ubiquitin Thiolesterase/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Targeting reversible post-translational modifications with PROTACs: a focus on enzymes modifying protein lysine and arginine residues.
Autorzy:
Pichlak, Marta (AUTHOR)
Sobierajski, Tomasz (AUTHOR)
Błażewska, Katarzyna M. (AUTHOR)
Gendaszewska-Darmach, Edyta (AUTHOR)
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Źródło:
Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-37. 37p.
Czasopismo naukowe
Tytuł:
The Correlations between the Intensity of Histopathological Ubiquitin-Specific Protease 11 Staining and Progression of Prostate Cancer.
Autorzy:
Kim, Jae Heon (AUTHOR)
Yang, Hee Jo (AUTHOR)
Lee, Kwang Woo (AUTHOR)
Park, Jae Joon (AUTHOR)
Lee, Chang-Ho (AUTHOR)
Jeon, Youn Soo (AUTHOR)
Kim, Jae Ho (AUTHOR)
Park, Suyeon (AUTHOR)
Song, Su Jung (AUTHOR)
Lee, Ji-Hye (AUTHOR)
Moon, Ahrim (AUTHOR)
Kim, Yon Hee (AUTHOR)
Song, Yun Seob (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Dec2023, Vol. 16 Issue 12, p1703. 13p.
Czasopismo naukowe
Tytuł:
Targeting USP8 Inhibits O‐GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Autorzy:
Tang, Jianing (AUTHOR)
Long, Guo (AUTHOR)
Hu, Kuan (AUTHOR)
Xiao, Desheng (AUTHOR)
Liu, Shuang (AUTHOR)
Xiao, Liang (AUTHOR)
Zhou, Ledu (AUTHOR)
Tao, Yongguang (AUTHOR)
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Źródło:
Advanced Science. 11/24/2023, Vol. 10 Issue 33, p1-16. 16p.
Czasopismo naukowe
Tytuł:
Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application.
Autorzy:
Gao, Hongli (AUTHOR)
Yin, Jianqiao (AUTHOR)
Ji, Ce (AUTHOR)
Yu, Xiaopeng (AUTHOR)
Xue, Jinqi (AUTHOR)
Guan, Xin (AUTHOR)
Zhang, Shuang (AUTHOR)
Liu, Xun (AUTHOR)
Xing, Fei (AUTHOR)
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Źródło:
Journal of Experimental & Clinical Cancer Research (17569966). 11/21/2023, Vol. 42 Issue 1, p1-22. 22p.
Czasopismo naukowe

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