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Tytuł:: Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease.
Autorzy:: Zhu N; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.; Department of Systems Biology, Columbia University Medical Center, New York, NY, USA.
Welch CL; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.
Wang J; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.; Department of Systems Biology, Columbia University Medical Center, New York, NY, USA.
Allen PM; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.
Gonzaga-Jauregui C; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Ma L; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.
King AK; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Krishnan U; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.
Rosenzweig EB; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.; Department of Medicine, Columbia University Medical Center, New York, NY, USA.
Ivy DD; Department of Pediatric Cardiology, Children's Hospital Colorado, Denver, CO, USA.
Austin ED; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.
Hamid R; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.
Pauciulo MW; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of CincinnatiCollege of Medicine, Cincinnati, OH, USA.
Lutz KA; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Nichols WC; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of CincinnatiCollege of Medicine, Cincinnati, OH, USA.
Reid JG; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Overton JD; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Baras A; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Dewey FE; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Shen Y; Department of Systems Biology, Columbia University Medical Center, New York, NY, USA.; Department of Biomedical Informatics, Columbia University, New York, NY, USA.
Chung WK; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA. .; Department of Medicine, Columbia University Medical Center, New York, NY, USA. .; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA. .; New York, USA. .; Pokaż więcej
Źródło:: Genome medicine [Genome Med] 2018 Jul 20; Vol. 10 (1), pp. 56. Date of Electronic Publication: 2018 Jul 20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Variation*
Heart Defects, Congenital/*complications
Heart Defects, Congenital/*genetics
Hypertension, Pulmonary/*complications
Hypertension, Pulmonary/*genetics
SOXF Transcription Factors/*genetics
Adolescent ; Adult ; Amino Acid Sequence ; Child ; Child, Preschool ; Female ; Genetic Predisposition to Disease ; Humans ; Infant ; Male ; Risk Factors ; SOXF Transcription Factors/chemistry

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