Size-dependent steady state saturation limit in biomolecular transport through nuclear membranes.
Autorzy:
Shakhi PK; Department of Physics, BITS Pilani K. K. Birla Goa Campus, Goa, India. Bijeesh MM; Department of Physics, BITS Pilani K. K. Birla Goa Campus, Goa, India. Hareesh J; Department of Physics, BITS Pilani K. K. Birla Goa Campus, Goa, India. Joseph T; Department of Physics, BITS Pilani K. K. Birla Goa Campus, Goa, India. Nandakumar P; Department of Physics, BITS Pilani K. K. Birla Goa Campus, Goa, India. K Varier G; Department of Physics, BITS Pilani K. K. Birla Goa Campus, Goa, India.
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Źródło:
PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0297738. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
Assessing the role of surface layer and molecular probe size in diffusion within meniscus tissue.
Autorzy:
Schwartz G; Department of Biomedical Engineering, University of Miami, Coral Gables, FL, United States of America. Best TM; Department of Orthopaedic Surgery, University of Miami, Miami, FL, United States of America.; UHealth Sports Medicine Institute, Coral Gables, FL, United States of America. Chen CB; Department of Industrial and Systems Engineering, University of Miami, Coral Gables, FL, United States of America. Travascio F; Department of Orthopaedic Surgery, University of Miami, Miami, FL, United States of America.; Department of Mechanical and Aerospace Engineering, University of Miami, Coral Gables, FL, United States of America.; Max Biedermann Institute for Biomechanics at Mount Sinai Medical Center, Miami Beach, FL, United States of America. Jackson AR; Department of Biomedical Engineering, University of Miami, Coral Gables, FL, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0301432. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
Role of aquaporin-4 polarization in extracellular solute clearance.
Autorzy:
Bojarskaite L; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway.; Department of Neurology, Oslo University Hospital, Oslo, 0027, Norway. Nafari S; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Ravnanger AK; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Frey MM; Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, 0317, Norway. Skauli N; Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, 0317, Norway. Åbjørsbråten KS; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Roth LC; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Amiry-Moghaddam M; Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, 0317, Norway. Nagelhus EA; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Ottersen OP; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Bogen IL; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway.; Section for Drug Abuse Research, Department of Forensic Sciences, Oslo University Hospital, P.O. Box N-4950, Nydalen, Oslo, 0424, Norway. Thoren AE; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. Enger R; GliaLab and Letten Centre, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, P.O.B. 1103, Oslo, 0317, Norway. .
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Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 Mar 26; Vol. 21 (1), pp. 28. Date of Electronic Publication: 2024 Mar 26.
Diffusion Mediates Molecular Transport through the Perivascular Space in the Brain.
Autorzy:
Tanaka M; Department of Neurology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan. Hirayoshi Y; Department of Neurology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan. Minatani S; Department of Neurology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan. Hasegawa I; Department of Neurology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan. Itoh Y; Department of Neurology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.
Polysaccharide from Artocarpus heterophyllus Lam. (Jackfruit) Pulp Ameliorates Dextran Sodium Sulfate-Induced Enteritis in Rats.
Autorzy:
Li Y; School of Food Science and Engineering, Hainan University, Haikou 570228, China.; Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wanning 571533, China. Chen Y; Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wanning 571533, China.; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. Li C; School of Food Science and Engineering, Hainan University, Haikou 570228, China. Wu G; Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wanning 571533, China. He Y; School of Food Science and Engineering, Hainan University, Haikou 570228, China. Tan L; Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wanning 571533, China. Zhu K; Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wanning 571533, China.; Key Laboratory of Processing Suitability and Quality Control of the Special Tropical Crops of Hainan Province, Wanning 571533, China.; National Center of Important Tropical Crops Engineering and Technology Research, Wanning 571533, China.
Synthesis and Characterization of a Novel Concentration-Independent Fluorescent Chloride Indicator, ABP-Dextran, Optimized for Extracellular Chloride Measurement.
Autorzy:
Normoyle KP; Massachusetts General Hospital, Department of Neurology, 55 Fruit Street, Boston, MA 02114, USA.; Harvard Medical School, Department of Neurology, 77 Louis Pasteur Avenue, Boston, MA 02115, USA. Lillis KP; Massachusetts General Hospital, Department of Neurology, 55 Fruit Street, Boston, MA 02114, USA.; Harvard Medical School, Department of Neurology, 77 Louis Pasteur Avenue, Boston, MA 02115, USA. Staley KJ; Massachusetts General Hospital, Department of Neurology, 55 Fruit Street, Boston, MA 02114, USA.; Harvard Medical School, Department of Neurology, 77 Louis Pasteur Avenue, Boston, MA 02115, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Jan 08; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 08.
Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice.
Autorzy:
Tong XJ; Department of Ophthalmology, University of California San Francisco, San Francisco, CA, 94131, USA. Akdemir G; Departments of Medicine and Physiology, University of California San Francisco, San Francisco, CA, 94131, USA. Wadhwa M; Departments of Medicine and Physiology, University of California San Francisco, San Francisco, CA, 94131, USA. Verkman AS; Departments of Medicine and Physiology, University of California San Francisco, San Francisco, CA, 94131, USA. Smith AJ; Department of Ophthalmology, University of California San Francisco, San Francisco, CA, 94131, USA. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 Jan 04; Vol. 21 (1), pp. 1. Date of Electronic Publication: 2024 Jan 04.
Differential roles of eNOS in late effects of VEGF-A on hyperpermeability in different types of endothelial cells.
Autorzy:
Bosma EK; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands. Darwesh S; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. Habani YI; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. Cammeraat M; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands. Serrano Martinez P; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands. van Breest Smallenburg ME; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands. Zheng JY; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. Vogels IMC; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. van Noorden CJF; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia. Schlingemann RO; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands.; Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Fondation Asile Des Aveugles, Lausanne, Switzerland. Klaassen I; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. .; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands. .; Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 05; Vol. 13 (1), pp. 21436. Date of Electronic Publication: 2023 Dec 05.
Novel transdermal curcumin therapeutic preserves endothelial barrier function in a high-dose LPS rat model.
Autorzy:
Nugent WH; Song Biotechnologies LLC, Cockeysville, MD, USA. Carr DA; Song Biotechnologies LLC, Cockeysville, MD, USA. Friedman J; Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY, USA.; Vascarta, Inc, Summit, NJ, USA. Song BK; Song Biotechnologies LLC, Cockeysville, MD, USA.; Vascarta, Inc, Summit, NJ, USA.
Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells.
Autorzy:
Dong P; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate Based Medicine, Shandong University, Qingdao, China. Lv H; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate Based Medicine, Shandong University, Qingdao, China. Jia W; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate Based Medicine, Shandong University, Qingdao, China. Liu J; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate Based Medicine, Shandong University, Qingdao, China. Wang S; Santolecan Pharmaceuticals LLC, Jupiter, FL, USA. Li X; Santolecan Pharmaceuticals LLC, Jupiter, FL, USA. Hu J; Santolecan Pharmaceuticals LLC, Jupiter, FL, USA. Zhao L; Santolecan Pharmaceuticals LLC, Jupiter, FL, USA. Shi Y; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate Based Medicine, Shandong University, Qingdao, China.
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Źródło:
Drug delivery [Drug Deliv] 2023 Dec; Vol. 30 (1), pp. 40-50.
Radiosensitizing Effect of Dextran-Coated Iron Oxide Nanoparticles on Malignant Glioma Cells.
Autorzy:
Tran NH; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, Politehnicheskaya 29, St. Petersburg 195251, Russia. Ryzhov V; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia. Volnitskiy A; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia. Amerkanov D; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.; National Research Center 'Kurchatov Institute', Akademika Kurchatova pl. 1, Moscow 123182, Russia. Pack F; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.; National Research Center 'Kurchatov Institute', Akademika Kurchatova pl. 1, Moscow 123182, Russia. Golubev AM; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia. Arutyunyan A; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia. Spitsyna A; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia. Burdakov V; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia. Lebedev D; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.; National Research Center 'Kurchatov Institute', Akademika Kurchatova pl. 1, Moscow 123182, Russia. Konevega AL; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, Politehnicheskaya 29, St. Petersburg 195251, Russia.; National Research Center 'Kurchatov Institute', Akademika Kurchatova pl. 1, Moscow 123182, Russia. Shtam T; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.; National Research Center 'Kurchatov Institute', Akademika Kurchatova pl. 1, Moscow 123182, Russia. Marchenko Y; Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», Orlova roscha 1, Gatchina 188300, Russia.
The Impact of COVID-19 on Cellular Factors Influencing Red Blood Cell Aggregation Examined in Dextran: Possible Causes and Consequences.
Autorzy:
Bosek M; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Wybranowski T; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Napiórkowska-Mastalerz M; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Pyskir J; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Cyrankiewicz M; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Pyskir M; Department of Rehabilitation, Faculty of Health Sciences, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Pilaczyńska-Cemel M; Department of Lung Diseases, Neoplasms and Tuberculosis, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Szołna-Chodór A; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Wrembel M; Department of Lung Diseases, Neoplasms and Tuberculosis, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Kruszewski S; Department of Biophysics, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland. Przybylski G; Department of Lung Diseases, Neoplasms and Tuberculosis, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland.
Effect of Polycan, a β-Glucan from Aureobasidium pullulans SM-2001, on Inflammatory Response and Intestinal Barrier Function in DSS-Induced Ulcerative Colitis.
Autorzy:
Do HJ; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea. Kim YS; Glucan Co., Ltd., 25-15, Worasan-ro 950 beon-gil, Munsan-eup, Jinju-si 52840, Gyeongsangnam-do, Republic of Korea. Oh TW; Korean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine (KIOM), Daegu 41062, Republic of Korea.; Department of Korean Convergence Medical Science, University of Science & Technology (UST), 1672 Yuseongdae-ro, Daejeon 34054, Yuseong-gu, Republic of Korea.
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