The Perfect Combination: Enhancing Patient Response to PD-1-Based Therapies in Epithelial Ovarian Cancer.
Autorzy:
James NE; Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants Hospital, Providence, RI 02905, USA. Woodman M; Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants Hospital, Providence, RI 02905, USA. DiSilvestroPA; Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants Hospital, Providence, RI 02905, USA.; Department of Obstetrics and Gynecology, Warren Alpert School of Medicine, Brown University, Providence, RI 02903, USA. Ribeiro JR; Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants Hospital, Providence, RI 02905, USA.; Department of Obstetrics and Gynecology, Warren Alpert School of Medicine, Brown University, Providence, RI 02903, USA.
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Źródło:
Cancers [Cancers (Basel)] 2020 Aug 03; Vol. 12 (8). Date of Electronic Publication: 2020 Aug 03.
The biomarker HE4 (WFDC2) promotes a pro-angiogenic and immunosuppressive tumor microenvironment via regulation of STAT3 target genes.
Autorzy:
James NE; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA. Emerson JB; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA.; Warren-Alpert Medical School of Brown University, Providence, RI, USA. Borgstadt AD; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA.; Warren-Alpert Medical School of Brown University, Providence, RI, USA. Beffa L; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA.; Warren-Alpert Medical School of Brown University, Providence, RI, USA. Oliver MT; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA.; Warren-Alpert Medical School of Brown University, Providence, RI, USA. Hovanesian V; Rhode Island Hospital, Digital Imaging and Analysis Core Facility, Providence, RI, USA. Urh A; Northwell Health Physician Partners Gynecologic Oncology, Brightwaters, NY, USA. Singh RK; University of Rochester Medical Center, Rochester, NY, USA. Rowswell-Turner R; University of Rochester Medical Center, Rochester, NY, USA. DiSilvestroPA; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA.; Warren-Alpert Medical School of Brown University, Providence, RI, USA. Ou J; Warren-Alpert Medical School of Brown University, Providence, RI, USA.; Women and Infants Hospital, Department of Pathology, Providence, RI, USA. Moore RG; University of Rochester Medical Center, Rochester, NY, USA. Ribeiro JR; Women and Infants Hospital, Department of Obstetrics and Gynecology, Program in Women's Oncology, Providence, RI, USA. .; Warren-Alpert Medical School of Brown University, Providence, RI, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 May 22; Vol. 10 (1), pp. 8558. Date of Electronic Publication: 2020 May 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells.
Autorzy:
James NE; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Cantillo E; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA. Oliver MT; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA. Rowswell-Turner RB; Department of Pharmacy, University of Rhode Island, Kingston, RI, USA. Ribeiro JR; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA. Kim KK; Department of Pharmacy, University of Rhode Island, Kingston, RI, USA. Chichester CO 3rd; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. DiSilvestroPA; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA. Moore RG; Department of Pharmacy, University of Rhode Island, Kingston, RI, USA. Singh RK; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.; Department of Pharmacy, University of Rhode Island, Kingston, RI, USA. Yano N; Department of Obstetrics and Gynecology, Program in Women's Oncology, Women and Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA. Zhao TC; Department of Surgery, Roger Williams Medical Center, Providence, RI, USA.
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