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Wyszukujesz frazę ""Diabetes Mellitus, Experimental"" wg kryterium: Temat


Tytuł :
Dysfunction of Cullin 3 RING E3 ubiquitin ligase causes vasoconstriction and increased sodium reabsorption in diabetes.
Autorzy :
Zhang Y; Department of Nephrology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Guo Q; Department of Nephrology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiang G; Department of Nephrology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang C; Department of Nephrology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Oct 15; Vol. 710, pp. 109000. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cullin Proteins/*metabolism
Diabetes Mellitus, Experimental/*metabolism
Diabetes Mellitus, Experimental/*physiopathology
Sodium/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Vasoconstriction/*physiology
Animals ; Aorta/metabolism ; Aorta/pathology ; Cells, Cultured ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 1/pathology ; Diabetes Mellitus, Type 1/physiopathology ; Humans ; Kidney/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Microfilament Proteins/antagonists & inhibitors ; Nerve Tissue Proteins/antagonists & inhibitors ; Protein-Serine-Threonine Kinases/metabolism ; Rats ; rho GTP-Binding Proteins/antagonists & inhibitors ; rho-Associated Kinases/metabolism ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
Tytuł :
Cardioprotective effect of icariin against myocardial fibrosis and its molecular mechanism in diabetic cardiomyopathy based on network pharmacology: Role of ICA in DCM.
Autorzy :
Zhang L; Department of Cardiology, The First Hospital of Jilin University, Changchun 130021, PR China. Electronic address: .
Wang S; Department of Cardiology, The First Hospital of Jilin University, Changchun 130021, PR China. Electronic address: .
Li Y; Department of Hematology, The First Hospital of Jilin University, Changchun 130021, PR China. Electronic address: .
Wang Y; Department of Cardiology, The First Hospital of Jilin University, Changchun 130021, PR China. Electronic address: .
Dong C; Department of Abdominal Ultrasound, The First Hospital of Jilin University, Changchun 130021, PR China. Electronic address: .
Xu H; Department of Echocardiography, The First Hospital of Jilin University, Changchun 130021, PR China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Oct; Vol. 91, pp. 153607. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/pathology
Diabetes Mellitus, Type 2*/pathology
Diabetic Cardiomyopathies*/drug therapy
Cardiotonic Agents/*pharmacology
Flavonoids/*pharmacology
Animals ; Fibrosis ; Myocardium/pathology ; Rats
Czasopismo naukowe
Tytuł :
Sarsasapogenin attenuates Alzheimer-like encephalopathy in diabetes.
Autorzy :
Zhang YM; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
Zheng T; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
Huang TT; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
Gu PP; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
Gou LS; Center for Genetic Medicine, Xuzhou Maternity and Child Health Care Hospital, Xuzhou 221009, Jiangsu, China.
Ma TF; Institute for Stem Cell and Neural Regeneration, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
Liu YW; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China; Department of Pharmacology, School of Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Oct; Vol. 91, pp. 153686. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/drug therapy
Diabetes Mellitus, Experimental*/chemically induced
Diabetes Mellitus, Experimental*/drug therapy
Brain Diseases/*drug therapy
Spirostans/*pharmacology
Amyloid Precursor Protein Secretases ; Amyloid beta-Peptides/metabolism ; Animals ; Aspartic Acid Endopeptidases ; Cell Line ; Glycogen Synthase Kinase 3 beta ; Hippocampus/drug effects ; Hippocampus/metabolism ; PPAR gamma ; Phosphorylation ; Rats ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1).
Autorzy :
Wu W; Department of General Medicine, The Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, People's Republic of China. Electronic address: .
Chai Q; Department of General Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, People's Republic of China.
Zhang Z; Department of General Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, People's Republic of China.
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Sep 30; Vol. 709, pp. 108968. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Glucose/*metabolism
Diabetes Mellitus, Experimental/*metabolism
Oxidative Stress/*physiology
Sodium-Glucose Transporter 1/*metabolism
Ventricular Dysfunction, Left/*metabolism
Animals ; Apoptosis/physiology ; Blood Glucose/analysis ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/complications ; Gene Knockdown Techniques ; Heart Ventricles/metabolism ; Heart Ventricles/pathology ; Male ; Membrane Potential, Mitochondrial/physiology ; Mice, Inbred C57BL ; Mitochondria/metabolism ; Mitochondrial Dynamics/physiology ; Myocytes, Cardiac/metabolism ; Sodium-Glucose Transporter 1/genetics ; Up-Regulation/physiology ; Ventricular Dysfunction, Left/blood ; Ventricular Dysfunction, Left/etiology
Czasopismo naukowe
Tytuł :
[Molecular mechanism of Gegen Qinlian Decoction in promoting differentiation of brown adipose tissue to improve glucose and lipid metabolism disorders in diabetic rats].
Autorzy :
Zhang XQ; Jiangxi Province Key Laboratory of Traditional Chinese Medicine Etiopathogenisis & Research Center for Differentiation and Development of Traditional Chinese Medicine Basic Theory, Jiangxi University of Chinese Medicine Nanchang 330004, China Key Laboratory of Traditional Chinese Medicine Pharmacology of Jiangxi Province Nanchang 330004, China.
Xu WH; Jiangxi Province Key Laboratory of Traditional Chinese Medicine Etiopathogenisis & Research Center for Differentiation and Development of Traditional Chinese Medicine Basic Theory, Jiangxi University of Chinese Medicine Nanchang 330004, China.
Xiao X; Jiangxi Province Key Laboratory of Traditional Chinese Medicine Etiopathogenisis & Research Center for Differentiation and Development of Traditional Chinese Medicine Basic Theory, Jiangxi University of Chinese Medicine Nanchang 330004, China.
Ding JF; Jiangxi Province Key Laboratory of Traditional Chinese Medicine Etiopathogenisis & Research Center for Differentiation and Development of Traditional Chinese Medicine Basic Theory, Jiangxi University of Chinese Medicine Nanchang 330004, China.
Jiang Y; Jiangxi Province Key Laboratory of Traditional Chinese Medicine Etiopathogenisis & Research Center for Differentiation and Development of Traditional Chinese Medicine Basic Theory, Jiangxi University of Chinese Medicine Nanchang 330004, China Key Laboratory of Traditional Chinese Medicine Pharmacology of Jiangxi Province Nanchang 330004, China.
Tu J; Jiangxi Province Key Laboratory of Traditional Chinese Medicine Etiopathogenisis & Research Center for Differentiation and Development of Traditional Chinese Medicine Basic Theory, Jiangxi University of Chinese Medicine Nanchang 330004, China.
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Źródło :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2021 Sep; Vol. 46 (17), pp. 4462-4470.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/genetics
Lipid Metabolism Disorders*
Adipose Tissue, Brown ; Animals ; Drugs, Chinese Herbal ; Fibronectins ; Glucose ; Lipid Metabolism ; Rats
Czasopismo naukowe
Tytuł :
Melatonin attenuates aortic oxidative stress injury and apoptosis in STZ-diabetes rats by Notch1/Hes1 pathway.
Autorzy :
Ren BC; Department of Rheumatology and Immunology, Second Affiliated Hospital of Xi'an Jiaotong University, Xi`an, Shaanxi, China. Electronic address: .
Zhang W; Department of Cardiovascular Surgery, Fuwai Hospital Chinese Academy of Medical Sciences, ShenZhen, China. Electronic address: .
Zhang W; Department of Cardiovascular Surgery, Second Affiliated Hospital of Xi'an Jiaotong University, Xi`an, Shaanxi, China. Electronic address: .
Ma JX; Department of Cardiovascular Surgery, Second Affiliated Hospital of Xi'an Jiaotong University, Xi`an, Shaanxi, China. Electronic address: .
Pei F; Department of Cardiovascular Surgery, Second Affiliated Hospital of Xi'an Jiaotong University, Xi`an, Shaanxi, China. Electronic address: .
Li BY; Department of Cardiovascular Surgery, Second Affiliated Hospital of Xi'an Jiaotong University, Xi`an, Shaanxi, China. Electronic address: .
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2021 Sep; Vol. 212, pp. 105948. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*therapeutic use
Diabetes Mellitus, Experimental/*drug therapy
Hypoglycemic Agents/*therapeutic use
Melatonin/*therapeutic use
Animals ; Antioxidants/pharmacology ; Aorta, Thoracic/cytology ; Apoptosis/drug effects ; Blood Glucose/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/metabolism ; Hypoglycemic Agents/pharmacology ; Male ; Melatonin/pharmacology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Oxidative Stress/drug effects ; Rats, Sprague-Dawley ; Receptor, Notch1/metabolism ; Signal Transduction/drug effects ; Transcription Factor HES-1/metabolism
Czasopismo naukowe
Tytuł :
Mitochondrial transplantation in cardiomyocytes: foundation, methods, and outcomes.
Autorzy :
Ali Pour P; Edwards Lifesciences Center for Advanced Cardiovascular Technology, Irvine, California.; Department of Biomedical Engineering, University of California, Irvine, California.
Hosseinian S; Edwards Lifesciences Center for Advanced Cardiovascular Technology, Irvine, California.; School of Medicine, University of California, Irvine, California.
Kheradvar A; Edwards Lifesciences Center for Advanced Cardiovascular Technology, Irvine, California.; Department of Biomedical Engineering, University of California, Irvine, California.; School of Medicine, University of California, Irvine, California.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 Sep 01; Vol. 321 (3), pp. C489-C503. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Cardiomyopathies/*therapy
Diabetes Mellitus, Experimental/*therapy
Mitochondria, Heart/*transplantation
Myocardial Infarction/*therapy
Myocardial Reperfusion Injury/*therapy
Myocytes, Cardiac/*metabolism
Animals ; Cardiomyopathies/metabolism ; Cardiomyopathies/pathology ; Cell Fractionation/methods ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Disease Models, Animal ; Humans ; Injections, Intralesional ; Mitochondria, Heart/physiology ; Mitochondria, Heart/ultrastructure ; Mitochondrial Dynamics/physiology ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/pathology ; Oxidative Phosphorylation ; Rabbits ; Rats ; Reactive Oxygen Species/metabolism ; Swine
Czasopismo naukowe
Tytuł :
Metformin prevents p-tau and amyloid plaque deposition and memory impairment in diabetic mice.
Autorzy :
Oliveira WH; Postgraduate Program in Biological Sciences/Center of Biosciences, Federal University of Pernambuco (UFPE), Recife, PE, CEP 50670-420, Brazil.; Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil.
Braga CF; Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil.
Lós DB; Postgraduate Program in Biotechnology/Northeast Network in Biotechnology (RENORBIO), Federal University of Pernambuco (UFPE), Recife, PE, Brazil.
Araújo SMR; Postgraduate Program in Biological Sciences/Center of Biosciences, Federal University of Pernambuco (UFPE), Recife, PE, CEP 50670-420, Brazil.
França MR; Postgraduate Program in Biological Sciences/Center of Biosciences, Federal University of Pernambuco (UFPE), Recife, PE, CEP 50670-420, Brazil.; Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil.; Postgraduate Program in Biotechnology/Northeast Network in Biotechnology (RENORBIO), Federal University of Pernambuco (UFPE), Recife, PE, Brazil.; Postgraduate Program in Biosciences and Biotechnology for Health (PPGBBS), Oswaldo Cruz Foundation (FIOCRUZ-PE)/Aggeu Magalhães Institute (IAM), Recife, PE, Brazil.; Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Rio de Janeiro, Brazil.
Duarte-Silva E; Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil.; Postgraduate Program in Biosciences and Biotechnology for Health (PPGBBS), Oswaldo Cruz Foundation (FIOCRUZ-PE)/Aggeu Magalhães Institute (IAM), Recife, PE, Brazil.
Rodrigues GB; Postgraduate Program in Biological Sciences/Center of Biosciences, Federal University of Pernambuco (UFPE), Recife, PE, CEP 50670-420, Brazil.; Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil.
Rocha SWS; Postgraduate Program in Biological Sciences/Center of Biosciences, Federal University of Pernambuco (UFPE), Recife, PE, CEP 50670-420, Brazil.
Peixoto CA; Laboratory of Ultrastructure, Aggeu Magalhães Institute (IAM), FIOCRUZ, Av. Moraes Rego S/N, Recife, PE, Brazil. .; Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Rio de Janeiro, Brazil. .
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Źródło :
Experimental brain research [Exp Brain Res] 2021 Sep; Vol. 239 (9), pp. 2821-2839. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/complications
Alzheimer Disease*/drug therapy
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Type 2*
Metformin*/pharmacology
Amyloid beta-Peptides ; Animals ; Disease Models, Animal ; Mice ; Mice, Transgenic ; Plaque, Amyloid ; tau Proteins
Czasopismo naukowe
Tytuł :
CHIP-overexpressing Wharton's jelly-derived mesenchymal stem cells attenuate hyperglycemia-induced oxidative stress-mediated kidney injuries in diabetic rats.
Autorzy :
Ali A; Department of Biological Science and Technology, China Medical University, Taichung, 404, Taiwan.
Shibu MA; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Since Medical Foundation, Hualien, 970, Taiwan.
Kuo CH; Laboratory of Exercise Biochemistry, University of Taipei, Taipei, Taiwan.
Lo JF; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan.
Chen RJ; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Day CH; Department of Nursing, MeiHo University, Pingtung, 91202, Taiwan.
Ho TJ; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
PadmaViswanadha V; Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.
Kuo WW; Department of Biological Science and Technology, China Medical University, Taichung, 404, Taiwan; Ph.D. Program for Biotechnology Industry, China Medical University, Taichung, 406, Taiwan.
Huang CY; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Since Medical Foundation, Hualien, 970, Taiwan; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 404, Taiwan; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan; Department of Biotechnology, Asia University, Taichung, Taiwan; Center of General Education, Buddhist Tzu Chi Medical Foundation, Tzu Chi University of Science and Technology, Hualien, 970, Taiwan. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Sep; Vol. 173, pp. 70-80. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/metabolism
Hyperglycemia*/metabolism
Mesenchymal Stem Cells*
Wharton Jelly*
Animals ; Kidney/metabolism ; Oxidative Stress ; Rats
Czasopismo naukowe
Tytuł :
Human type 2 diabetes mellitus-associated transcriptional disturbances in a high-sugar diet long-term exposed Drosophila melanogaster.
Autorzy :
Loreto JS; Programa de Pós-graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.
Ferreira SA; Programa de Pós-graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.
Ardisson-Araújo DM; Programa de Pós-graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil; Laboratório de Virologia de Insetos, Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil. Electronic address: .
Barbosa NV; Programa de Pós-graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Avenida Roraima, 1000, 97105-900 Santa Maria, RS, Brazil. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2021 Sep; Vol. 39, pp. 100866. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental/*genetics
Diabetes Mellitus, Type 2/*genetics
Diet, Carbohydrate Loading/*adverse effects
Dietary Sugars/*adverse effects
Drosophila melanogaster/*genetics
Transcriptome/*drug effects
Animals ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Drosophila melanogaster/drug effects ; Drosophila melanogaster/metabolism ; Gene Expression Regulation ; Glucose/analysis ; Humans ; Oxidative Stress ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
Diabetes Impaired Ischemia-Induced PDGF (Platelet-Derived Growth Factor) Signaling Actions and Vessel Formation Through the Activation of Scr Homology 2-Containing Phosphatase-1.
Autorzy :
Mercier C; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Brazeau T; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Lamoureux J; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Boisvert E; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Robillard S; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Breton V; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Paré M; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Guay A; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Lizotte F; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Despatis MA; Department of Surgery (M.-A.D.), Université de Sherbrooke, Québec, Canada.
Geraldes P; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.; Division of Endocrinology, Department of Medicine (P.G.), Université de Sherbrooke, Québec, Canada.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Sep; Vol. 41 (9), pp. 2469-2482. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiogenesis Inducing Agents/*pharmacology
Diabetes Mellitus, Experimental/*enzymology
Diabetic Angiopathies/*enzymology
Hindlimb/*blood supply
Ischemia/*enzymology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Neovascularization, Physiologic/*drug effects
Platelet-Derived Growth Factor/*pharmacology
Protein Tyrosine Phosphatase, Non-Receptor Type 6/*metabolism
Animals ; Blood Glucose/metabolism ; Case-Control Studies ; Cattle ; Cell Hypoxia ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/physiopathology ; Diabetic Angiopathies/genetics ; Diabetic Angiopathies/physiopathology ; Enzyme Activation ; Humans ; Ischemia/physiopathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Protein Tyrosine Phosphatase, Non-Receptor Type 6/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
[Acupuncture intervention induced improvement of oxidative stress by regulating PKCβ/P66shc signaling in obese diabetic rats].
Autorzy :
Yin G; College of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230000, China.
Shen GM; College of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230000, China.
Jiang AJ; College of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230000, China.
Li JY; Graduate School of Anhui University of Chinese Medicine, Hefei 230000.
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Źródło :
Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2021 Aug 25; Vol. 46 (8), pp. 642-8.
Typ publikacji :
Journal Article
MeSH Terms :
Acupuncture Therapy*
Diabetes Mellitus, Experimental*/genetics
Diabetes Mellitus, Experimental*/therapy
Electroacupuncture*
Acupuncture Points ; Animals ; Male ; Obesity/genetics ; Obesity/therapy ; Oxidative Stress ; Rats ; Rats, Sprague-Dawley ; Src Homology 2 Domain-Containing, Transforming Protein 1
Czasopismo naukowe
Tytuł :
Sargassum fusiforme Alginate Relieves Hyperglycemia and Modulates Intestinal Microbiota and Metabolites in Type 2 Diabetic Mice.
Autorzy :
Liu J; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.; Department of Biotechnology and Bioengineering, Chonnam National University, Gwangju 500-757, Korea.
Wu S; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
Cheng Y; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
Liu Q; Bestchrom (Shanghai) Biosciences Co., Ltd., Shanghai 200120, China.
Su L; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
Yang Y; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
Zhang X; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
Wu M; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
Choi JI; Department of Biotechnology and Bioengineering, Chonnam National University, Gwangju 500-757, Korea.
Tong H; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China.
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Źródło :
Nutrients [Nutrients] 2021 Aug 22; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 22.
Typ publikacji :
Journal Article
MeSH Terms :
Alginates/*pharmacology
Diabetes Mellitus, Experimental/*drug therapy
Diabetes Mellitus, Type 2/*drug therapy
Hypoglycemic Agents/*pharmacology
Sargassum/*chemistry
Animals ; Blood Glucose/drug effects ; Cholesterol/blood ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/etiology ; Diet, High-Fat/adverse effects ; Gastrointestinal Microbiome/drug effects ; Hyperglycemia/blood ; Hyperglycemia/drug therapy ; Hyperglycemia/etiology ; Mice ; Streptozocin ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
Hearing Impairment in a Mouse Model of Diabetes Is Associated with Mitochondrial Dysfunction, Synaptopathy, and Activation of the Intrinsic Apoptosis Pathway.
Autorzy :
Lyu AR; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Department of Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kim TH; Biomedical Convergence Research Center, Chungnam National University Hospital, Daejeon 35015, Korea.
Shin SA; Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kim EH; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Yu Y; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Gajbhiye A; Department of Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Kwon HC; Department of Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Je AR; Electron Microscopy Research Center, Korea Basic Science Institute, Cheongju 28119, Korea.
Huh YH; Electron Microscopy Research Center, Korea Basic Science Institute, Cheongju 28119, Korea.
Park MJ; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Park YH; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Department of Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Korea.; Biomedical Convergence Research Center, Chungnam National University Hospital, Daejeon 35015, Korea.; Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 16; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*complications
Hearing Loss/*physiopathology
Mitochondria/*ultrastructure
Receptors, Leptin/*genetics
Animals ; Apoptosis ; Biomarkers/metabolism ; Cochlea/blood supply ; Cochlea/metabolism ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Disease Models, Animal ; Down-Regulation ; Hearing Loss/etiology ; Hearing Loss/genetics ; Hearing Loss/metabolism ; Humans ; Male ; Mice ; Microscopy, Electron, Transmission ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł :
Beneficial Effect of Quercetin on Erythrocyte Properties in Type 2 Diabetic Rats.
Autorzy :
Jasenovec T; Faculty of Medicine, Institute of Physiology, Comenius University in Bratislava, Sasinkova 2, 813 72 Bratislava, Slovakia.
Radosinska D; Faculty of Medicine, Institute of Immunology, Comenius University in Bratislava, Odborarske Namestie 14, 811 08 Bratislava, Slovakia.
Kollarova M; Faculty of Medicine, Institute of Physiology, Comenius University in Bratislava, Sasinkova 2, 813 72 Bratislava, Slovakia.
Balis P; Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská Cesta 9, 841 04 Bratislava, Slovakia.
Ferenczyova K; Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská Cesta 9, 841 04 Bratislava, Slovakia.
Kalocayova B; Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská Cesta 9, 841 04 Bratislava, Slovakia.
Bartekova M; Faculty of Medicine, Institute of Physiology, Comenius University in Bratislava, Sasinkova 2, 813 72 Bratislava, Slovakia.; Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská Cesta 9, 841 04 Bratislava, Slovakia.
Tothova L; Faculty of Medicine, Institute of Molecular Biomedicine, Comenius University in Bratislava, Sasinkova 4, 811 08 Bratislava, Slovakia.
Radosinska J; Faculty of Medicine, Institute of Physiology, Comenius University in Bratislava, Sasinkova 2, 813 72 Bratislava, Slovakia.; Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská Cesta 9, 841 04 Bratislava, Slovakia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 11; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*blood
Diabetes Mellitus, Experimental/*drug therapy
Diabetes Mellitus, Type 2/*blood
Diabetes Mellitus, Type 2/*drug therapy
Erythrocytes/*metabolism
Quercetin/*therapeutic use
Animals ; Antioxidants ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Erythrocyte Deformability/drug effects ; Erythrocytes/drug effects ; Lipid Metabolism/drug effects ; Male ; Nitric Oxide/metabolism ; Osmosis ; Oxidative Stress ; Quercetin/pharmacology ; Rats, Zucker
Czasopismo naukowe
Tytuł :
In Vivo and In Vitro Antidiabetic and Anti-Inflammatory Properties of Flax ( Linum usitatissimum L.) Seed Polyphenols.
Autorzy :
Mechchate H; Laboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FI-00014 Helsinki, Finland.
Es-Safi I; Laboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FI-00014 Helsinki, Finland.
Conte R; Research Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
Hano C; Laboratoire de Biologie des Ligneux et des Grandes Cultures, INRAE USC1328, Campus Eure et Loir, Orleans University, 45067 Orleans, France.
Amaghnouje A; Laboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.
Jawhari FZ; Laboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.
Radouane N; Laboratory of Functional Ecology and Environmental Engineering, Sidi Mohamed Ben Abdellah University, P.O. Box 2202, Fez 30000, Morocco.
Bencheikh N; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco.
Grafov A; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FI-00014 Helsinki, Finland.
Bousta D; Laboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.
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Źródło :
Nutrients [Nutrients] 2021 Aug 11; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Diabetes Mellitus, Experimental/*therapy
Flax/*chemistry
Hypoglycemic Agents/*pharmacology
Plant Oils/*pharmacology
Seeds/*chemistry
Animals ; Blood Glucose/drug effects ; Body Weight/drug effects ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/chemically induced ; Dietary Supplements ; Humans ; Mice ; Polyphenols/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Oral Fc-Coupled Preproinsulin Achieves Systemic and Thymic Delivery Through the Neonatal Fc Receptor and Partially Delays Autoimmune Diabetes.
Autorzy :
Corcos N; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Culina S; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Deligne C; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Lavaud C; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
You S; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Mallone R; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpitaux Universitaires de Paris Centre-Université de Paris, Cochin Hospital, Service de Diabétologie et Immunologie Clinique, Paris, France.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Aug 10; Vol. 12, pp. 616215. Date of Electronic Publication: 2021 Aug 10 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental/*prevention & control
Diabetes Mellitus, Type 1/*prevention & control
Histocompatibility Antigens Class I/*immunology
Insulin/*pharmacology
Protein Precursors/*pharmacology
Receptors, Fc/*immunology
Recombinant Fusion Proteins/*pharmacology
Thymus Gland/*immunology
Administration, Oral ; Animals ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/immunology ; Diabetes Mellitus, Type 1/genetics ; Diabetes Mellitus, Type 1/immunology ; Histocompatibility Antigens Class I/genetics ; Insulin/genetics ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Protein Precursors/genetics ; Receptors, Fc/genetics ; Recombinant Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
Modulatory effect of isopulegol on hepatic key enzymes of glucose metabolism in high-fat diet/streptozotocin-induced diabetic rats.
Autorzy :
Kalaivani K; Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, Tamil Nadu, India.
Sankaranarayanan C; Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, Tamil Nadu, India.
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Źródło :
Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Aug; Vol. 127 (4), pp. 318-326. Date of Electronic Publication: 2019 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Glucose/*analysis
Carbohydrate Metabolism/*drug effects
Cyclohexane Monoterpenes/*pharmacology
Diabetes Mellitus, Experimental/*drug therapy
Diet, High-Fat/*adverse effects
Liver/*enzymology
Streptozocin/*toxicity
Animals ; Antibiotics, Antineoplastic/toxicity ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Experimental/pathology ; Fructose-Bisphosphatase/metabolism ; Glucose-6-Phosphatase/metabolism ; Hexokinase/metabolism ; Hypoglycemic Agents/pharmacology ; Insulin/blood ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Hypoglycaemic and hypolipidemic activities of Alhagi camelorum in streptozotocin-induced diabetes in Wistar rats.
Autorzy :
Nabiyouni F; Department of Biology, Damghan Branch, Islamic Azad University, Semnan, Iran.
Vaezi G; Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Malekirad AA; Department of Biology, Payame Noor University, Tehran, Iran.
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Źródło :
Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Aug; Vol. 127 (4), pp. 296-303. Date of Electronic Publication: 2019 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Phytotherapy*
Antioxidants/*pharmacology
Diabetes Mellitus, Experimental/*drug therapy
Fabaceae/*chemistry
Hypoglycemic Agents/*pharmacology
Hypolipidemic Agents/*pharmacology
Plant Extracts/*pharmacology
Animals ; Blood Glucose/analysis ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Experimental/pathology ; Insulin/blood ; Lipids/blood ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Hippocampus kuda protein hydrolysate improves male reproductive dysfunction in diabetic rats.
Autorzy :
Sudirman S; Fisheries Product Technology, Faculty of Agriculture, Universitas Sriwijaya, Indralaya 30862, Indonesia. Electronic address: .
Su CY; Department of Food Science; National Taiwan Ocean University, Keelung City 20224, Taiwan. Electronic address: .
Tsou D; Department of Food Science; National Taiwan Ocean University, Keelung City 20224, Taiwan. Electronic address: .
Lee MC; Department of Aquaculture, National Taiwan Ocean University, Keelung City 20224, Taiwan. Electronic address: .
Kong ZL; Department of Food Science; National Taiwan Ocean University, Keelung City 20224, Taiwan. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Aug; Vol. 140, pp. 111760. Date of Electronic Publication: 2021 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Fish Proteins*
Smegmamorpha*
Diabetes Mellitus, Experimental/*drug therapy
Protein Hydrolysates/*therapeutic use
Reproduction/*drug effects
Animals ; Blood Glucose/drug effects ; Blood Glucose/immunology ; Cytokines/immunology ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/pathology ; Follicle Stimulating Hormone/blood ; Luteinizing Hormone/blood ; Male ; Oxidative Stress/drug effects ; Protein Hydrolysates/pharmacology ; Rats, Sprague-Dawley ; Sperm Count ; Sperm Motility/drug effects ; Spermatozoa/abnormalities ; Spermatozoa/drug effects ; Testis/drug effects ; Testis/pathology ; Testosterone/blood
Czasopismo naukowe

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