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Title:
Identification and Validation of the Pyroptosis-Related Hub Gene Signature and the Associated Regulation Axis in Diabetic Keratopathy.
Authors:
Cui Y; Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27101, USA.
Wang L; Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Liang W; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27101, USA.
Huang L; Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Zhuang S; College of Integrated Traditional Chinese and Western Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Shi H; College of Integrated Traditional Chinese and Western Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Xu N; Department of Ophthalmology, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian, China.
Hu J; Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
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Source:
Journal of diabetes research [J Diabetes Res] 2024 Mar 18; Vol. 2024, pp. 2920694. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/genetics
Pyroptosis*/genetics
Animals ; Rats ; Computational Biology ; Cyclooxygenase 2 ; Interleukin-18 ; Streptozocin ; TNF Receptor-Associated Factor 6
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Exploring mitochondrial metabolism of wild-type and diabetic mice skin explants using the Seahorse technology.
Authors:
Dugrain J; SFR BioSciences, Skin Functional Integrity group. Laboratory for Tissue Biology and Therapeutics Engineering (LBTI) CNRS UMR5305 - University of Lyon, Lyon, France.
Canaple L; SFR BioSciences, Skin Functional Integrity group. Laboratory for Tissue Biology and Therapeutics Engineering (LBTI) CNRS UMR5305 - University of Lyon, Lyon, France.; SFR BioSciences, UAR 3444, US8, ENS de Lyon, UCBL, AniRA ImmOs, Lyon, France.
Picard N; SFR BioSciences, Skin Functional Integrity group. Laboratory for Tissue Biology and Therapeutics Engineering (LBTI) CNRS UMR5305 - University of Lyon, Lyon, France.
Sigaudo-Roussel D; SFR BioSciences, Skin Functional Integrity group. Laboratory for Tissue Biology and Therapeutics Engineering (LBTI) CNRS UMR5305 - University of Lyon, Lyon, France.
Bonod C; SFR BioSciences, Skin Functional Integrity group. Laboratory for Tissue Biology and Therapeutics Engineering (LBTI) CNRS UMR5305 - University of Lyon, Lyon, France.
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Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2024 Mar; Vol. 30 (3), pp. e13638.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/chemically induced
Diabetes Mellitus, Experimental*/metabolism
Mice ; Humans ; Animals ; Mitochondria/metabolism ; Energy Metabolism ; Oxygen Consumption ; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone/metabolism ; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone/pharmacology
Academic Journal
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Title:
Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging.
Authors:
Wang Y; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Li F; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Mao L; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Liu Y; Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, Beihang University, Beijing, 100191, China.
Chen S; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Liu J; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Huang K; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Chen Q; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Wu J; Department of Ultrasound in Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Lu L; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Zheng Y; Department of Ultrasound in Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Shen W; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China.
Ying T; Department of Ultrasound in Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. .
Dai Y; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. .; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China. .
Shen Y; Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. .; Shanghai Clinical Research Center for Interventional Medicine, Shanghai, 200025, China. .
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Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 01; Vol. 22 (1), pp. 85. Date of Electronic Publication: 2024 Mar 01.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Humans ; Mice ; Animals ; Reactive Oxygen Species/metabolism ; Endothelial Cells/metabolism ; Molybdenum/pharmacology ; Molybdenum/therapeutic use ; Hydrogen Peroxide/metabolism ; Autophagy
Academic Journal
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Title:
The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice.
Authors:
Vercalsteren E; NeuroCardioMetabol Group, Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, 118 83, Stockholm, Sweden. .
Karampatsi D; NeuroCardioMetabol Group, Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, 118 83, Stockholm, Sweden.
Buizza C; Translational Neurology Group, Department of Clinical Science, Wallenberg Neuroscience Center and Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Nyström T; NeuroCardioMetabol Group, Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, 118 83, Stockholm, Sweden.
Klein T; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Paul G; Translational Neurology Group, Department of Clinical Science, Wallenberg Neuroscience Center and Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Patrone C; NeuroCardioMetabol Group, Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, 118 83, Stockholm, Sweden. .
Darsalia V; NeuroCardioMetabol Group, Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, 118 83, Stockholm, Sweden. .
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Source:
Cardiovascular diabetology [Cardiovasc Diabetol] 2024 Feb 29; Vol. 23 (1), pp. 88. Date of Electronic Publication: 2024 Feb 29.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sodium-Glucose Transporter 2 Inhibitors*/pharmacology
Sodium-Glucose Transporter 2 Inhibitors*/therapeutic use
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Humans ; Mice ; Animals ; Glucosides/pharmacology ; Glucosides/therapeutic use ; Benzhydryl Compounds/pharmacology ; Benzhydryl Compounds/therapeutic use
Academic Journal
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Title:
Salvianolic Acid B Alleviates High Glucose-Induced Vascular Smooth Muscle Cell Inflammation by Upregulating the miR-486a-5p Expression.
Authors:
Zhang ML; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Zhang MN; Department of Clinical Laboratory, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Chen H; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Wang X; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Zhao K; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Li X; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Song X; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
Tong F; Department of Critical Care Medicine, The Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang, Hebei 050000, China.
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Source:
Mediators of inflammation [Mediators Inflamm] 2024 Feb 16; Vol. 2024, pp. 4121166. Date of Electronic Publication: 2024 Feb 16 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
MicroRNAs*/metabolism
Diabetes Mellitus, Type 2*/metabolism
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Benzofurans*
Depsides*
Humans ; Animals ; Mice ; Muscle, Smooth, Vascular ; Cells, Cultured ; Inflammation/metabolism ; Glucose/toxicity ; Glucose/metabolism ; Cell Proliferation ; Myocytes, Smooth Muscle/metabolism
Academic Journal
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Title:
Effect of Mexican Propolis on Wound Healing in a Murine Model of Diabetes Mellitus.
Authors:
Canales-Alvarez O; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Zacatenco, Ciudad de México 07738, Mexico.; Laboratorio de Investigación Biomédica en Productos Naturales, Carrera de Medicina, UNAM, FES Iztacala, Avenida de los Barrios Número 1, Tlalnepantla 54090, Estado de México, Mexico.
Canales-Martinez MM; Laboratorio de Farmacognosia, UBIPRO, UNAM, FES Iztacala, Avenida de los Barrios Número 1, Tlalnepantla 54090, Estado de México, Mexico.
Dominguez-Verano P; Laboratorio de Investigación Biomédica en Productos Naturales, Carrera de Medicina, UNAM, FES Iztacala, Avenida de los Barrios Número 1, Tlalnepantla 54090, Estado de México, Mexico.
Balderas-Cordero D; Laboratorio de Investigación Biomédica en Productos Naturales, Carrera de Medicina, UNAM, FES Iztacala, Avenida de los Barrios Número 1, Tlalnepantla 54090, Estado de México, Mexico.
Madrigal-Bujaidar E; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Zacatenco, Ciudad de México 07738, Mexico.
Álvarez-González I; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Zacatenco, Ciudad de México 07738, Mexico.
Rodriguez-Monroy MA; Laboratorio de Investigación Biomédica en Productos Naturales, Carrera de Medicina, UNAM, FES Iztacala, Avenida de los Barrios Número 1, Tlalnepantla 54090, Estado de México, Mexico.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 12; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 12.
Publication Type:
Journal Article
MeSH Terms:
Propolis*/pharmacology
Propolis*/therapeutic use
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/complications
Humans ; Mice ; Animals ; Matrix Metalloproteinase 9/metabolism ; Disease Models, Animal ; Actins ; Wound Healing
Academic Journal
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Title:
Altered N6-Methyladenosine Modification Patterns and Transcript Profiles Contributes to Cognitive Dysfunction in High-Fat Induced Diabetic Mice.
Authors:
Cao Z; School of Nursing, Peking University, Beijing 100191, China.
An Y; Endocrinology Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Lu Y; School of Nursing, Peking University, Beijing 100191, China.
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International journal of molecular sciences [Int J Mol Sci] 2024 Feb 06; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 06.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/genetics
Cognitive Dysfunction*/genetics
Mice ; Animals ; Mice, Inbred C57BL ; Methyltransferases/metabolism ; RNA ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Mammals/metabolism
Academic Journal
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Title:
MCC950 Ameliorates Diabetic Muscle Atrophy in Mice by Inhibition of Pyroptosis and Its Synergistic Effect with Aerobic Exercise.
Authors:
Yan X; Key Laboratory of Exercise and Physical Fitness of Ministry of Education, Beijing Sport University, Beijing 100084, China.; School of Sport Science, Beijing Sport University, Beijing 100084, China.
Fu P; School of Sport Science, Beijing Sport University, Beijing 100084, China.; Department of Physical Education, Northwestern Polytechnical University, Xi'an 710072, China.
Zhang Y; Key Laboratory of Exercise and Physical Fitness of Ministry of Education, Beijing Sport University, Beijing 100084, China.; School of Sport Science, Beijing Sport University, Beijing 100084, China.
Ling D; School of Sport Science, Beijing Sport University, Beijing 100084, China.
Reynolds L; Department of Clinical Sciences in Malmö, Lund University Diabetes Centre, Lund University, 21428 Malmö, Sweden.; NanoLund Center for NanoScience, Lund University, 22100 Lund, Sweden.
Hua W; School of Sport Science, Beijing Sport University, Beijing 100084, China.
Wang Z; School of Sport Science, Beijing Sport University, Beijing 100084, China.
Ma F; School of Sport Science, Beijing Sport University, Beijing 100084, China.; School of Life Sciences, Nankai University, Tianjin 300071, China.
Li B; School of Sport Science, Beijing Sport University, Beijing 100084, China.; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong SAR 999077, China.
Yu J; Key Laboratory of Exercise and Physical Fitness of Ministry of Education, Beijing Sport University, Beijing 100084, China.
Liu Y; School of Sport Science, Beijing Sport University, Beijing 100084, China.; Institute of Physical Education, Jiangsu Normal University, Xuzhou 221116, China.
Gong L; Key Laboratory of Exercise and Physical Fitness of Ministry of Education, Beijing Sport University, Beijing 100084, China.
Zhang E; Department of Clinical Sciences in Malmö, Lund University Diabetes Centre, Lund University, 21428 Malmö, Sweden.; NanoLund Center for NanoScience, Lund University, 22100 Lund, Sweden.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 04; Vol. 29 (3). Date of Electronic Publication: 2024 Feb 04.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/therapy
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/therapy
Diabetic Neuropathies*
Mice ; Animals ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Inflammasomes ; Pyroptosis ; Sulfonamides/pharmacology ; Mice, Inbred Strains ; Exercise ; Muscular Atrophy/drug therapy ; Muscular Atrophy/etiology
Academic Journal
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Title:
Clinacanthus nutans leaf extract reduces pancreatic β-cell apoptosis by inhibiting JNK activation and modulating oxidative stress and inflammation in streptozotocin-induced diabetic rats.
Authors:
Susanti N; Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.; Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University, Malang, Indonesia.
Mustika A; Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Khotib J; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia.
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Open veterinary journal [Open Vet J] 2024 Feb; Vol. 14 (2), pp. 730-737. Date of Electronic Publication: 2024 Feb 29.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Rodent Diseases*
Rats ; Male ; Animals ; Streptozocin/therapeutic use ; Caspase 3/metabolism ; Rats, Wistar ; Oxidative Stress ; Apoptosis ; Inflammation/drug therapy ; Inflammation/veterinary ; Plant Extracts/pharmacology ; Plant Extracts/chemistry
Academic Journal
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Title:
TIFA contributes to periodontitis in diabetic mice via activating the NF‑κB signaling pathway.
Authors:
Guo X; Department of Periodontology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
Qiao G; Department of Oral and Maxillofacial Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
Wang J; Department of Periodontology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
Yang C; Department of Periodontology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
Zhao M; Department of Periodontology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
Zhang Q; Department of Periodontology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
Wan Y; Department of Prosthodontics and Oral Implantology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, P.R. China.
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Molecular medicine reports [Mol Med Rep] 2024 Feb; Vol. 29 (2). Date of Electronic Publication: 2023 Dec 15.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/genetics
Diabetes Mellitus, Experimental*/metabolism
Periodontitis*/genetics
Periodontitis*/metabolism
Animals ; Humans ; Mice ; Inflammation/metabolism ; Lipopolysaccharides/pharmacology ; NF-kappa B/metabolism ; Osteoclasts/metabolism ; RANK Ligand/genetics ; RANK Ligand/metabolism ; Receptor Activator of Nuclear Factor-kappa B/metabolism ; Signal Transduction
Academic Journal
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Title:
Edible wild plants, chicory and purslane, alleviated diabetic testicular dysfunction, and insulin resistance via suppression 8OHdg and oxidative stress in rats.
Authors:
Saad EA; Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Hassan HA; Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Ghoneum MH; Department of Surgery, Charles Drew University of Medicine and Science, Los Angeles, CA, United States of America.; Department of Surgery, University of California Los Angeles, Los Angeles, CA, United States of America.
Alaa El-Dein M; Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
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PloS one [PLoS One] 2024 Apr 11; Vol. 19 (4), pp. e0301454. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
Portulaca*/metabolism
Insulin Resistance*
Cichorium intybus*
Diabetes Mellitus, Experimental*/metabolism
Testicular Diseases*/drug therapy
Humans ; Rats ; Male ; Animals ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Antioxidants/metabolism ; 8-Hydroxy-2'-Deoxyguanosine/metabolism ; Plants, Edible/metabolism ; Blood Glucose/metabolism ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Oxidative Stress ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Inflammation ; Glutathione/metabolism ; Cholesterol/pharmacology
Academic Journal
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Title:
Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation.
Authors:
He J; Department of Orthopedics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, P. R. China.
Zhou S; Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, P. R. China.
Wang J; Department of Orthopedics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, P. R. China.
Sun B; Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, P. R. China.
Ni D; Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China. .
Wu J; Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, P. R. China. .
Peng X; Department of Orthopedics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, P. R. China. .
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Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 16; Vol. 22 (1), pp. 116. Date of Electronic Publication: 2024 Mar 16.
Publication Type:
Journal Article
MeSH Terms:
Nanofibers*
Diabetes Mellitus, Experimental*
Chitosan*/metabolism
Succinates*
Mice ; Animals ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Macrophages/metabolism ; Antioxidants/pharmacology ; Wound Healing
Academic Journal
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Title:
High-throughput sequencing reveals differences in microbial community structure and diversity in the conjunctival tissue of healthy and type 2 diabetic mice.
Authors:
Li F; Department of Opthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Yang S; Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, Zhejiang, China.
Ma J; Core Laboratory, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, 266042, Shandong, China.
Zhao X; Core Laboratory, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, 266042, Shandong, China.
Chen M; Department of Opthalmology, Qingdao municipal hospital, Qingdao Municipal Hospital, No. 5 Donghai Middle Road, Shinan District, Qingdao, 266000, China. .
Wang Y; Core Laboratory, The Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, 266042, Shandong, China. .
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BMC microbiology [BMC Microbiol] 2024 Mar 16; Vol. 24 (1), pp. 90. Date of Electronic Publication: 2024 Mar 16.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*
Microbiota*
Diabetes Mellitus, Type 2*
Animals ; Mice ; Fungi/genetics ; Bacteria/genetics ; High-Throughput Nucleotide Sequencing
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus.
Authors:
Ma XM; Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China.; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China.; Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou, Luzhou, 646000, Sichuan, People's Republic of China.; Sichuan Clinical Research Center for Nephropathy, Luzhou, 646000, Sichuan, People's Republic of China.
Geng K; Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou, Luzhou, 646000, Sichuan, People's Republic of China.; Sichuan Clinical Research Center for Nephropathy, Luzhou, 646000, Sichuan, People's Republic of China.
Wang P; Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China.; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China.
Jiang Z; Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China.; Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou, Luzhou, 646000, Sichuan, People's Republic of China.; Sichuan Clinical Research Center for Nephropathy, Luzhou, 646000, Sichuan, People's Republic of China.
Law BY; Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China. .; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China. .
Xu Y; Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China. .; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, People's Republic of China. .; Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China. .; Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou, Luzhou, 646000, Sichuan, People's Republic of China. .; Sichuan Clinical Research Center for Nephropathy, Luzhou, 646000, Sichuan, People's Republic of China. .
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Cardiovascular diabetology [Cardiovasc Diabetol] 2024 Mar 14; Vol. 23 (1), pp. 96. Date of Electronic Publication: 2024 Mar 14.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Diabetic Cardiomyopathies*/etiology
Animals ; Humans ; Mice ; Energy Metabolism ; Inflammation ; Lactic Acid/metabolism ; Models, Statistical ; Prognosis
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Melatonin reduces lung injury in type 1 diabetic mice by the modulation of autophagy.
Authors:
Rezaie J; Solid Tumor Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran.
Jahanghiri M; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Heris RM; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hassannezhad S; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Abdyazdani N; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Rahbarghazi A; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmadi M; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. .
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BMC molecular and cell biology [BMC Mol Cell Biol] 2024 Mar 14; Vol. 25 (1), pp. 7. Date of Electronic Publication: 2024 Mar 14.
Publication Type:
Journal Article
MeSH Terms:
Lung Injury*/drug therapy
Melatonin*/pharmacology
Melatonin*/therapeutic use
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Type 1*/complications
Diabetes Mellitus, Type 1*/drug therapy
Animals ; Mice ; Interleukin-6 ; Autophagy
Academic Journal
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Title:
A Recombinant Peptide Device Combined with Adipose Tissue-Derived Stem Cells Enhances Subcutaneous Islet Engraftment.
Authors:
Mizui T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-0872, Japan.; Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Inagaki A; Division of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Nakamura Y; Division of Pathology, Graduate School of Medicine, Tohoku Medical and Pharmaceutical University, Sendai 983-8536, Japan.
Imura T; Division of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Uematsu SS; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-0872, Japan.
Miyagi S; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-0872, Japan.
Kamei T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-0872, Japan.
Unno M; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-0872, Japan.
Watanabe K; Division of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Goto M; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai 980-0872, Japan.; Division of Transplantation and Regenerative Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
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Cells [Cells] 2024 Mar 13; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 13.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*
Mice ; Animals ; Mice, Inbred C57BL ; Adipose Tissue ; Stem Cells ; Peptides
Academic Journal
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Title:
Transient but not chronic hyperglycemia accelerates ocular glymphatic transport.
Authors:
Delle C; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Wang X; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, 14642, Rochester, NY, USA.; School of Medicine, University of California, San Francisco, 10 Koret Way, 94117, San Francisco, CA, USA.
Giannetto M; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, 14642, Rochester, NY, USA.
Newbold E; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, 14642, Rochester, NY, USA.
Peng W; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, 14642, Rochester, NY, USA.
Gomolka RS; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Ladrón-de-Guevara A; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, 14642, Rochester, NY, USA.
Cankar N; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Schiøler Nielsen E; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Kjaerby C; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Weikop P; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Mori Y; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.
Nedergaard M; Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen N, Denmark. .; Center for Translational Neuromedicine, University of Rochester Medical School, Elmwood Avenue 601, 14642, Rochester, NY, USA. .
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Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 Mar 12; Vol. 21 (1), pp. 26. Date of Electronic Publication: 2024 Mar 12.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*
Hyperglycemia*
Mice ; Humans ; Animals ; Blood Glucose ; Biological Transport
Academic Journal
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Title:
The Validation and Determination of Empagliflozin Concentration in the Presence of Grapefruit Juice Using HPLC for Pharmacokinetic Applications.
Authors:
Abu Dayyih W; Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
Zakaraya Z; Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19328, Jordan.
Hailat M; Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan.
Al-Tawarah NM; Faculty of Allied Medical Sciences, Medical Laboratory Sciences, Mutah University, Al-Karak 61710, Jordan.
Alkharabsheh S; Faculty of Allied Medical Sciences, Medical Laboratory Sciences, Mutah University, Al-Karak 61710, Jordan.
Nadher HK; Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.
Hailat Z; Department of Information Systems, Yarmouk University, Irbid 21163, Jordan.
Alarman SM; Faculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.
Khaleel A; Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.
Awad R; Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 11; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 11.
Publication Type:
Journal Article
MeSH Terms:
Citrus paradisi*
Citrus*/chemistry
Diabetes Mellitus, Experimental*
Diabetes Mellitus, Type 2*
Benzhydryl Compounds*
Glucosides*
Rats ; Animals ; Chromatography, High Pressure Liquid ; Beverages ; Area Under Curve
Academic Journal
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Title:
Desert date seed extract-loaded chitosan nanoparticles ameliorate hyperglycemia and insulin deficiency through the reduction in oxidative stress and inflammation.
Authors:
Farid A; Biotechnology Department, Faculty of Science, Cairo University, Giza, Egypt. .
Ahmed A; Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
Alaa O; Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
Safwat G; Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
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Source:
Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5829. Date of Electronic Publication: 2024 Mar 09.
Publication Type:
Journal Article
MeSH Terms:
Chitosan*/chemistry
Diabetes Mellitus, Experimental*/drug therapy
Hyperglycemia*
Nanoparticles*/chemistry
Rats ; Animals ; Insulin/metabolism ; Hypoglycemic Agents/pharmacology ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Rats, Sprague-Dawley ; Oxidative Stress ; Seeds/metabolism ; Inflammation/drug therapy
Academic Journal
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Title:
Sex-specific epigenetics drive low GPER expression in gastrointestinal smooth muscles in type 2 diabetic mice.
Authors:
Muhammad A; Department of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL, 36088, USA.; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, P.M.B. 1044, Zaria, Kaduna State, Nigeria.
Hixon JC; Department of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL, 36088, USA.
Pharmacy Yusuf A; Department of Biochemistry, Federal University of Technology, P.M.B 65, Minna, Niger State, Nigeria.
Rivas Zarete JI; Department of Biomedical Sciences, College of Veterinary Medicine, Tuskegee University, Tuskegee, AL, 36088, USA.
Johnson I; Department of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL, 36088, USA.
Miller J; Department of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL, 36088, USA.
Adu-Addai B; Department of Biomedical Sciences, College of Veterinary Medicine, Tuskegee University, Tuskegee, AL, 36088, USA.
Yates C; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mahavadi S; Department of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL, 36088, USA. .
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Source:
Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5633. Date of Electronic Publication: 2024 Mar 07.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Experimental*/genetics
Male ; Mice ; Female ; Humans ; Animals ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Estrogens ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Muscle, Smooth/metabolism ; Epigenesis, Genetic ; RNA, Messenger
Academic Journal
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Showing 1-20 from 6619 results

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