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Wyszukujesz frazę ""Differentiation"" wg kryterium: Temat


Tytuł :
Itolizumab, an anti-CD6 monoclonal antibody, as a potential treatment for COVID-19 complications.
Autorzy :
Loganathan S; Clinical Sciences, Clinical Development and Medical Affairs, Biocon Biologics India Ltd , Bengaluru, India.
Athalye SN; Clinical Sciences, Clinical Development and Medical Affairs, Biocon Biologics India Ltd , Bengaluru, India.
Joshi SR; Consultant, Joshi Clinic and Lilavati Hospital , Mumbai, India.
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Źródło :
Expert opinion on biological therapy [Expert Opin Biol Ther] 2020 Sep; Vol. 20 (9), pp. 1025-1031. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Betacoronavirus*
Antibodies, Monoclonal, Humanized/*therapeutic use
Antigens, CD/*immunology
Antigens, Differentiation, T-Lymphocyte/*immunology
Coronavirus Infections/*drug therapy
Coronavirus Infections/*immunology
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*immunology
Antibodies, Monoclonal, Humanized/pharmacology ; Cell Differentiation/drug effects ; Cell Differentiation/physiology ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cytokines/antagonists & inhibitors ; Cytokines/immunology ; Humans ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/physiology ; Pandemics ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Enhanced differentiation of human dopaminergic neuronal cell model for preclinical translational research in Parkinson's disease.
Autorzy :
Harischandra DS; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Rokad D; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Ghaisas S; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Verma S; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Robertson A; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Jin H; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Anantharam V; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Kanthasamy A; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA.
Kanthasamy AG; Department of Biomedical Sciences, Parkinson's Disorder Research Program, Iowa State University, Ames, IA, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Apr 01; Vol. 1866 (4), pp. 165533. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Differentiation*
Models, Neurological*
Translational Medical Research*
Dopaminergic Neurons/*metabolism
Neural Stem Cells/*metabolism
Parkinson Disease/*metabolism
Antigens, Differentiation/biosynthesis ; Cell Line ; Dopaminergic Neurons/pathology ; Humans ; Neural Stem Cells/pathology ; Parkinson Disease/pathology ; Parkinson Disease/therapy
Czasopismo naukowe
Tytuł :
Morphological characterization of pirarucu Arapaima gigas (Schinz, 1822) gonadal differentiation.
Autorzy :
da Costa Amaral A; Programa de Pós-graduação em Ciências Pesqueiras nos Trópicos, Universidade Federal do Amazonas, Manaus, Brazil.
Lima AF; Embrapa Pesca e Aquicultura, Palmas, Brazil.
Ganeco-Kirschnik LN; Embrapa Pesca e Aquicultura, Palmas, Brazil.
de Almeida FL; Embrapa Amazônia Ocidental, Manaus, Brazil.
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Źródło :
Journal of morphology [J Morphol] 2020 Apr; Vol. 281 (4-5), pp. 491-499. Date of Electronic Publication: 2020 Mar 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Sex Differentiation*
Fishes/*anatomy & histology
Gonads/*anatomy & histology
Animals ; Cell Differentiation ; Female ; Fishes/growth & development ; Fishes/physiology ; Male ; Ovary/anatomy & histology ; Ovary/cytology ; Testis/anatomy & histology ; Testis/growth & development ; Vitellogenesis
Czasopismo naukowe
Tytuł :
MicroRNA-200c promotes osteogenic differentiation of human bone mesenchymal stem cells through activating the AKT/β-Catenin signaling pathway via downregulating Myd88.
Autorzy :
Xia P; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Gu R; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China.
Zhang W; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Shao L; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China.
Li F; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China.
Wu C; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China.
Sun Y; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2019 Dec; Vol. 234 (12), pp. 22675-22686. Date of Electronic Publication: 2019 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Osteogenesis*
Mesenchymal Stem Cells/*enzymology
MicroRNAs/*metabolism
Myeloid Differentiation Factor 88/*metabolism
Pelvic Bones/*enzymology
Proto-Oncogene Proteins c-akt/*metabolism
beta Catenin/*metabolism
Alkaline Phosphatase/metabolism ; Calcium/metabolism ; Cell Proliferation ; Cells, Cultured ; Gene Expression Regulation, Enzymologic ; Humans ; MicroRNAs/genetics ; Myeloid Differentiation Factor 88/genetics ; Osteocalcin/metabolism ; Pelvic Bones/cytology ; Proto-Oncogene Proteins c-akt/genetics ; Signal Transduction ; beta Catenin/genetics
Czasopismo naukowe
Tytuł :
microRNA-132 inhibits osteogenic differentiation of periodontal ligament stem cells via GDF5 and the NF-κB signaling pathway.
Autorzy :
Xu Y; Department of Orthodontics, Beijing Stomotological Hospital, Capital Medical University, Beijing 100006, PR China.
Ren C; Department of Orthodontics, Beijing Stomotological Hospital, Capital Medical University, Beijing 100006, PR China.
Zhao X; Department of General Dentistry, Beijing Stomotological Hospital, Capital Medical University, Beijing 100006, PR China.
Wang W; Department of Orthodontics, Beijing Stomotological Hospital, Capital Medical University, Beijing 100006, PR China.
Zhang N; Department of Orthodontics, Beijing Stomotological Hospital, Capital Medical University, Beijing 100006, PR China. Electronic address: .
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Źródło :
Pathology, research and practice [Pathol Res Pract] 2019 Dec; Vol. 215 (12), pp. 152722. Date of Electronic Publication: 2019 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Osteogenesis*
Growth Differentiation Factor 5/*metabolism
MicroRNAs/*metabolism
NF-kappa B/*metabolism
Periodontal Ligament/*metabolism
Stem Cells/*metabolism
Adolescent ; Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Bone Morphogenetic Protein 2/genetics ; Bone Morphogenetic Protein 2/metabolism ; Cells, Cultured ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Growth Differentiation Factor 5/genetics ; Humans ; MicroRNAs/genetics ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Periodontal Ligament/cytology ; Signal Transduction ; Young Adult
Czasopismo naukowe
Tytuł :
Bone morphogenetic protein 2 promotes human trophoblast cell invasion and endothelial-like tube formation through ID1-mediated upregulation of IGF binding protein-3.
Autorzy :
Zhao HJ; Department of Cardiology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, P.R. China.; Department of Obstetrics and Gynaecology, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Klausen C; Department of Obstetrics and Gynaecology, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Zhu H; Department of Obstetrics and Gynaecology, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Chang HM; Department of Obstetrics and Gynaecology, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Li Y; School of Medicine, Shandong University, Jinan, China.; Center for Reproductive Medicine, Shandong University, Jinan, China.; The Key Laboratory of Reproductive Endocrinology, Ministry of Education, Jinan, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China.
Leung PCK; Department of Obstetrics and Gynaecology, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Feb; Vol. 34 (2), pp. 3151-3164. Date of Electronic Publication: 2020 Jan 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Cell Movement*
Bone Morphogenetic Protein 2/*pharmacology
Endothelial Cells/*metabolism
Trophoblasts/*metabolism
Cell Line ; Cells, Cultured ; Endothelial Cells/cytology ; Humans ; Inhibitor of Differentiation Protein 1/genetics ; Inhibitor of Differentiation Protein 1/metabolism ; Insulin-Like Growth Factor Binding Protein 3/genetics ; Insulin-Like Growth Factor Binding Protein 3/metabolism ; Placenta Growth Factor/metabolism ; Trophoblasts/cytology ; Trophoblasts/drug effects ; Trophoblasts/physiology ; Up-Regulation
Czasopismo naukowe
Tytuł :
Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose-derived stem cells.
Autorzy :
Gonçalves AI; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal.
Berdecka D; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal.
Rodrigues MT; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal.; The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Guimarães, Portugal.
Eren AD; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Cell Biology-Inspired Tissue Engineering, Maastricht, The Netherlands.
de Boer J; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Cell Biology-Inspired Tissue Engineering, Maastricht, The Netherlands.
Reis RL; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal.; The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Guimarães, Portugal.
Gomes ME; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga, Portugal.; The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Guimarães, Portugal.
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Źródło :
Journal of tissue engineering and regenerative medicine [J Tissue Eng Regen Med] 2019 Dec; Vol. 13 (12), pp. 2204-2217. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Adipose Tissue/*metabolism
Pluripotent Stem Cells/*metabolism
Tendons/*metabolism
Adipose Tissue/cytology ; Adult ; Antigens, Differentiation ; Female ; Humans ; Pluripotent Stem Cells/cytology ; Tendons/cytology
Czasopismo naukowe
Tytuł :
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer.
Autorzy :
Baker LA; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Holliday H; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Roden D; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Krisp C; Australian Proteome Analysis Facility (APAF), Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.; Mass Spectrometric Proteome Analysis, Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
Wu SZ; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Junankar S; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Serandour AA; Cancer Research UK, The University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Mohammed H; Cancer Research UK, The University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Nair R; Rajiv Gandhi Centre for Biotechnology, Thycaud Post, Poojappura, Thiruvananthapuram, Kerala, 695014, India.
Sankaranarayanan G; Cancer Research UK, The University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Law AMK; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
McFarland A; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.
Simpson PT; Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
Lakhani S; Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Pathology Queensland, The Royal Brisbane and Women's Hospital, Herston, , Brisbane, QLD, Australia.
Dodson E; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Selinger C; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.
Anderson L; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, 2006, Australia.
Samimi G; National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, MD, 20892, USA.
Hacker NF; School of Women's and Children's Health, University of New South Wales, and Gynaecological Cancer Centre, Royal Hospital for Women, Sydney, NSW, Australia.
Lim E; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Ormandy CJ; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Naylor MJ; School of Medical Sciences and Bosch Institute, Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.
Simpson K; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, 3052, Australia.
Nikolic I; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
O'Toole S; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia.; Sydney Medical School, University of Sydney, Sydney, NSW, 2006, Australia.
Kaplan W; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.
Cowley MJ; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia.
Carroll JS; Cancer Research UK, The University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Molloy M; Australian Proteome Analysis Facility (APAF), Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.
Swarbrick A; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia. .; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia. .
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Źródło :
Breast cancer research : BCR [Breast Cancer Res] 2020 Jun 11; Vol. 22 (1), pp. 63. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*genetics
Breast Neoplasms/*metabolism
Carcinoma, Basal Cell/*genetics
Carcinoma, Basal Cell/*metabolism
Inhibitor of Differentiation Proteins/*genetics
Inhibitor of Differentiation Proteins/*metabolism
Animals ; Apoptosis/physiology ; Breast Neoplasms/pathology ; Carcinoma, Basal Cell/pathology ; Cell Differentiation/physiology ; Cell Line, Tumor ; Cell Proliferation/physiology ; Chromatin/genetics ; Chromatin/metabolism ; DNA Damage ; Female ; Heterografts ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Prognosis ; Proteogenomics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Gonad differentiation toward ovary.
Autorzy :
Lamothe S; Service d'endocrinologie, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris, 75012 Paris, France; Sorbonne université, Paris, France.
Bernard V; Service d'endocrinologie, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris, 75012 Paris, France; Sorbonne université, Paris, France.
Christin-Maitre S; Service d'endocrinologie, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris, 75012 Paris, France; Sorbonne université, Paris, France; UMR 933 75012 Paris, France. Electronic address: .
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Źródło :
Annales d'endocrinologie [Ann Endocrinol (Paris)] 2020 Jun; Vol. 81 (2-3), pp. 83-88. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gonads/*physiology
Ovary/*physiology
Sex Determination Processes/*physiology
Sex Differentiation/*genetics
Animals ; Cell Differentiation/genetics ; Female ; Gene Expression Regulation, Developmental ; Gonads/embryology ; Gonads/growth & development ; Humans ; Male ; Ovary/embryology ; Ovary/growth & development ; Phenotype ; Sexual Development/genetics ; Sexual Development/physiology
Czasopismo naukowe
Tytuł :
Bone morphogenetic proteins 2, 6, and 9 differentially regulate the osteogenic differentiation of immortalized preodontoblasts.
Autorzy :
Cao Y; Stomatological Hospital of Chongqing Medical University, Chongqing, China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, College of Stomatology, Chongqing Medical University, Chongqing, China.
Tan Q; Stomatological Hospital of Chongqing Medical University, Chongqing, China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, College of Stomatology, Chongqing Medical University, Chongqing, China.
Li J; Stomatological Hospital of Chongqing Medical University, Chongqing, China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, College of Stomatology, Chongqing Medical University, Chongqing, China.
Wang J; Stomatological Hospital of Chongqing Medical University, Chongqing, China.; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, The Affiliated Hospital of Stomatology of Chongqing Medical University, Chongqing, China.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, College of Stomatology, Chongqing Medical University, Chongqing, China.
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Źródło :
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas [Braz J Med Biol Res] 2020; Vol. 53 (9), pp. e9750. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Animals ; Bone Morphogenetic Protein 2 ; Bone Morphogenetic Protein 6 ; Cell Proliferation ; Cells, Cultured ; Gene Expression Regulation ; Growth Differentiation Factor 2 ; Mice ; Odontoblasts ; Osteogenesis ; Rats ; Signal Transduction
Czasopismo naukowe
Tytuł :
Monocyte isolation techniques significantly impact the phenotype of both isolated monocytes and derived macrophages in vitro.
Autorzy :
Nielsen MC; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
Andersen MN; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Møller HJ; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
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Źródło :
Immunology [Immunology] 2020 Jan; Vol. 159 (1), pp. 63-74. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell Differentiation*
Flow Cytometry*
Cell Separation/*methods
Lipopolysaccharide Receptors/*metabolism
Macrophages/*physiology
Monocytes/*physiology
Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Biomarkers ; Cell Adhesion ; Cells, Cultured ; Humans ; Interleukin-6/metabolism ; Lectins, C-Type/metabolism ; Macrophages/immunology ; Macrophages/metabolism ; Mannose-Binding Lectins/metabolism ; Monocytes/immunology ; Monocytes/metabolism ; Phenotype ; Receptors, Cell Surface/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Surface Epitaxial Crystallization-Directed Nanotopography for Accelerating Preosteoblast Proliferation and Osteogenic Differentiation.
Autorzy :
Yin HM; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
Liu W; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
Huang YF; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
Ren Y; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
Xu L; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
Xu JZ; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
Zhao B; Department of Anesthesiology , Guangzhou Women and Children's Medical Center , Guangzhou 510623 , China.
Li ZM; College of Polymer Science and Engineering and State Key Laboratory of Polymer Materials Engineering , Sichuan University , Chengdu 610065 , China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2019 Nov 20; Vol. 11 (46), pp. 42956-42963. Date of Electronic Publication: 2019 Nov 11.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Osteogenesis*
Nanostructures/*chemistry
Osteoblasts/*metabolism
Polyesters/*chemistry
Animals ; Antigens, Differentiation/biosynthesis ; Cell Line ; Mice ; Osteoblasts/cytology ; Surface Properties
Czasopismo naukowe
Tytuł :
The IFITM protein family in adaptive immunity.
Autorzy :
Yánez DC; UCL Great Ormond Street Institute of Child Health, London, UK.; School of Medicine, Universidad San Francisco de Quito, Quito, Ecuador.
Ross S; UCL Great Ormond Street Institute of Child Health, London, UK.
Crompton T; UCL Great Ormond Street Institute of Child Health, London, UK.
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Źródło :
Immunology [Immunology] 2020 Apr; Vol. 159 (4), pp. 365-372. Date of Electronic Publication: 2019 Dec 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adaptive Immunity*
Antigens, Differentiation/*immunology
Asthma/*immunology
Th1 Cells/*immunology
Th2 Cells/*immunology
Virus Diseases/*immunology
Animals ; Antigens, Differentiation/genetics ; Asthma/genetics ; Asthma/pathology ; Cell Differentiation ; Cell Membrane/immunology ; Cell Membrane/metabolism ; Endosomes/immunology ; Endosomes/metabolism ; Gene Expression Regulation ; Humans ; Inflammation ; Mice ; Protein Isoforms/genetics ; Protein Isoforms/immunology ; Signal Transduction ; Th1 Cells/metabolism ; Th2 Cells/metabolism ; Virus Diseases/genetics ; Virus Diseases/pathology ; Virus Diseases/virology ; Viruses/immunology ; Viruses/pathogenicity
Czasopismo naukowe
Tytuł :
Fabrication and properties of an injectable sodium alginate/PRP composite hydrogel as a potential cell carrier for cartilage repair.
Autorzy :
Gao X; Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Gao L; School of Life Science, Ningxia University, Yinchuan, China.
Groth T; Biomedical Materials Group, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.; Interdisciplinary Center of Materials Research, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Liu T; Department of Spinal Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
He D; Agricultural Products Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang, China.
Wang M; Department of Obstetrics and Gynecology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Gong F; Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.; Department of Spinal Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Chu J; Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zhao M; Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
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Źródło :
Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2019 Sep; Vol. 107 (9), pp. 2076-2087. Date of Electronic Publication: 2019 May 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cartilage*/injuries
Cartilage*/metabolism
Cartilage*/pathology
Cell Differentiation*
Cells, Immobilized*/metabolism
Cells, Immobilized*/transplantation
Chondrogenesis*
Alginates/*chemistry
Hydrogels/*chemistry
Mesenchymal Stem Cells/*metabolism
Animals ; Antigens, Differentiation/biosynthesis ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Multifaceted effects of soluble human CD6 in experimental cancer models.
Autorzy :
Simões IT; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Aranda F; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain .
Casadó-Llombart S; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Velasco-de Andrés M; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Català C; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Álvarez P; Departamento de Biología Molecular, Universidad de Cantabria-IDIVAL, Santander, Cantabria, Spain.
Consuegra-Fernández M; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Orta-Mascaró M; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Merino R; Instituto de Biomedicina y Biotecnología de Cantabria, CSIC-UC, Santander, Cantabria, Spain.
Merino J; Departamento de Biología Molecular, Universidad de Cantabria-IDIVAL, Santander, Cantabria, Spain.
Alberola-Ila J; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
González-Aseguinolaza G; Gene Therapy and Regulation of Gene Expression Program, Universidad de Navarra, Pamplona, Navarra, Spain.
Carreras E; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Martínez V; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain.
Lozano F; Immunoreceptors del Sistema Innat i Adaptatiu, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Catalunya, Spain .; Departament de Biomedicina, Facultat de Medicina, Universitat de Barcelona, Barcelona, Barcelona, Spain.; Servei d'Immunologia, Hospital Clínic de Barcelona, Barcelona, Spain.
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Źródło :
Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Mar; Vol. 8 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*blood
Antigens, Differentiation, T-Lymphocyte/*blood
Lung Neoplasms/*immunology
Lymphoma, T-Cell/*immunology
Melanoma, Experimental/*immunology
Sarcoma, Experimental/*immunology
T-Lymphocytes, Regulatory/*immunology
Activated-Leukocyte Cell Adhesion Molecule/immunology ; Activated-Leukocyte Cell Adhesion Molecule/metabolism ; Animals ; Antigens, CD/administration & dosage ; Antigens, CD/biosynthesis ; Antigens, CD/genetics ; Antigens, Differentiation, T-Lymphocyte/administration & dosage ; Antigens, Differentiation, T-Lymphocyte/biosynthesis ; Antigens, Differentiation, T-Lymphocyte/genetics ; Apoptosis/physiology ; Cell Differentiation/physiology ; Cell Line, Tumor ; Female ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/secondary ; Lymphoma, T-Cell/metabolism ; Male ; Melanoma, Experimental/blood ; Melanoma, Experimental/pathology ; Melanoma, Experimental/therapy ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/blood ; Recombinant Proteins/genetics ; Sarcoma, Experimental/blood ; Sarcoma, Experimental/pathology ; T-Lymphocytes, Regulatory/metabolism
Czasopismo naukowe
Tytuł :
Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification.
Autorzy :
Chang KC; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA. Electronic address: .
Sun C; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Cameron EG; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Madaan A; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Wu S; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA; Eye, Ear, Nose, & Throat Hospital, Department of Ophthalmology & Visual Science, Fudan University, 200031 Shanghai, China.
Xia X; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Zhang X; Shiley Eye Center, University of California San Diego, La Jolla, CA 92093, USA.
Tenerelli K; Shiley Eye Center, University of California San Diego, La Jolla, CA 92093, USA.
Nahmou M; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Knasel CM; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Russano KR; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA; Shiley Eye Center, University of California San Diego, La Jolla, CA 92093, USA; Bascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Hertz J; Bascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Goldberg JL; Spencer Center for Vision Research, Byers Eye Institute, School of Medicine, Stanford University, Palo Alto, CA 94304, USA; Shiley Eye Center, University of California San Diego, La Jolla, CA 92093, USA; Bascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
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Źródło :
Current biology : CB [Curr Biol] 2019 Jun 17; Vol. 29 (12), pp. 1963-1975.e5. Date of Electronic Publication: 2019 May 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Differentiation*
Growth Differentiation Factor 15/*genetics
Retinal Ganglion Cells/*physiology
Animals ; Growth Differentiation Factor 15/metabolism ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Concomitant deletion of SLAM-family receptors, NKG2D and DNAM-1 reveals gene redundancy of NK cell activating receptors in NK cell development and education.
Autorzy :
Chen S; School of Medicine and Institute for Immunology, Beijing Key Lab for Immunological Research on Chronic Diseases, Tsinghua University, Beijing, China.; Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing, China.
Dong Z; School of Medicine and Institute for Immunology, Beijing Key Lab for Immunological Research on Chronic Diseases, Tsinghua University, Beijing, China.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Apr; Vol. 107 (4), pp. 561-572. Date of Electronic Publication: 2019 Nov 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Antigens, Differentiation, T-Lymphocyte/*metabolism
Killer Cells, Natural/*cytology
Killer Cells, Natural/*metabolism
NK Cell Lectin-Like Receptor Subfamily K/*metabolism
Signaling Lymphocytic Activation Molecule Family/*metabolism
Animals ; Cell Differentiation ; Cell Division ; Hematopoiesis ; Mice, Knockout ; T-Box Domain Proteins/metabolism
Czasopismo naukowe
Tytuł :
Differential Responsiveness to BMP9 between Patent and Fused Suture Progenitor Cells from Craniosynostosis Patients.
Autorzy :
Song D; Chengdu, Chongqing, and Nanchang, People's Republic of China; and Chicago, Ill. From the State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University; the Ministry of Education Key Laboratory of Diagnostic Medicine and the Affiliated Hospitals of Chongqing Medical University; the Department of Clinical Laboratory Medicine, Second Affiliated Hospital of Nanchang University; the Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, and the Department of Surgery, Laboratory of Craniofacial Biology and Development, Section of Plastic Surgery, University of Chicago Medical Center.
Huang S
Zhang L
Liu W
Huang B
Feng Y
Liu B
He TC
Huang D
Reid RR
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Źródło :
Plastic and reconstructive surgery [Plast Reconstr Surg] 2020 Mar; Vol. 145 (3), pp. 552e-562e.
Typ publikacji :
Journal Article
MeSH Terms :
Cranial Sutures/*pathology
Craniosynostoses/*genetics
Growth Differentiation Factor 2/*metabolism
Mesenchymal Stem Cells/*pathology
Osteogenesis/*genetics
Calcium-Binding Proteins/genetics ; Cell Differentiation/genetics ; Cranial Sutures/cytology ; Cranial Sutures/surgery ; Craniosynostoses/pathology ; Craniosynostoses/surgery ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Infant ; Male ; Osteoblasts/physiology ; Osteoclasts/physiology ; Primary Cell Culture ; Reconstructive Surgical Procedures
Czasopismo naukowe
Tytuł :
Silencing of Growth Differentiation Factor-15 Promotes Breast Cancer Cell Invasion by Down-regulating Focal Adhesion Genes.
Autorzy :
Gkretsi V; Department of Life Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus .
Stylianou A; Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus.
Kalli M; Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus.
Louca M; Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus.
Voutouri C; Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus.
Zaravinos A; Department of Life Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus.; College of Medicine, Member of QU Health, Qatar University, Doha, Qatar.
Stylianopoulos T; Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus .
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Źródło :
Anticancer research [Anticancer Res] 2020 Mar; Vol. 40 (3), pp. 1375-1385.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*genetics
Focal Adhesions/*genetics
Growth Differentiation Factor 15/*genetics
Breast Neoplasms/pathology ; Cell Differentiation ; Cell Line, Tumor ; Down-Regulation ; Female ; Humans
Czasopismo naukowe
Tytuł :
Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation.
Autorzy :
Shirai K; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Obara K; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Tohgi N; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Yamazaki A; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Aki R; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Hamada Y; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Arakawa N; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan.
Singh SR; Basic Research Laboratory, National Cancer Institute, Frederic, MD, 21702, USA. Electronic address: .
Hoffman RM; AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California San Diego, CA, USA. Electronic address: .
Amoh Y; Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Japan. Electronic address: .
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Źródło :
Tissue & cell [Tissue Cell] 2019 Aug; Vol. 59, pp. 33-38. Date of Electronic Publication: 2019 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Gene Expression Regulation*
Autoantigens/*biosynthesis
Hair Follicle/*metabolism
Keratinocytes/*metabolism
Non-Fibrillar Collagens/*biosynthesis
Pluripotent Stem Cells/*metabolism
Animals ; Antigens, Differentiation/biosynthesis ; Hair Follicle/cytology ; Keratinocytes/cytology ; Mice ; Nestin/biosynthesis ; Pluripotent Stem Cells/cytology
Czasopismo naukowe

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