Skocz do pozycji: 1.

Tytuł:

Development and validation of a new dynamic in vitro model of the piglet colon (PigutIVM): application to the study of probiotics.

Autorzy:

Fleury MA; UMR UCA INRA 454 MEDIS, Centre de Recherche en Nutrition Humaine, Université Clermont Auvergne, 63000, Clermont-Ferrand, France.; Laboratoire de Ploufragan-Plouzané, ANSES, 22440, Ploufragan, France.; Université Bretagne Loire, 35044, Rennes, France.
Le Goff O; UMR UCA INRA 454 MEDIS, Centre de Recherche en Nutrition Humaine, Université Clermont Auvergne, 63000, Clermont-Ferrand, France.
Denis S; UMR UCA INRA 454 MEDIS, Centre de Recherche en Nutrition Humaine, Université Clermont Auvergne, 63000, Clermont-Ferrand, France.
Chaucheyras-Durand F; UMR UCA INRA 454 MEDIS, Centre de Recherche en Nutrition Humaine, Université Clermont Auvergne, 63000, Clermont-Ferrand, France.; Lallemand Animal Nutrition, 31702, Blagnac, France.
Jouy E; Laboratoire de Ploufragan-Plouzané, ANSES, 22440, Ploufragan, France.; Université Bretagne Loire, 35044, Rennes, France.
Kempf I; Laboratoire de Ploufragan-Plouzané, ANSES, 22440, Ploufragan, France.; Université Bretagne Loire, 35044, Rennes, France.
Alric M; UMR UCA INRA 454 MEDIS, Centre de Recherche en Nutrition Humaine, Université Clermont Auvergne, 63000, Clermont-Ferrand, France.
Blanquet-Diot S; UMR UCA INRA 454 MEDIS, Centre de Recherche en Nutrition Humaine, Université Clermont Auvergne, 63000, Clermont-Ferrand, France. .

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Źródło:

Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2017 Mar; Vol. 101 (6), pp. 2533-2547. Date of Electronic Publication: 2017 Feb 10.

Typ publikacji:

Journal Article; Validation Study

MeSH Terms:

Bioreactors*
Diffusion Chambers, Culture*
Gastrointestinal Microbiome/*drug effects
Microbial Consortia/*drug effects
Probiotics/*pharmacology
Anaerobiosis ; Animals ; Anti-Bacterial Agents/pharmacology ; Colistin/pharmacology ; Colon/drug effects ; Colon/microbiology ; Escherichia coli/drug effects ; Escherichia coli/growth & development ; Feces/microbiology ; Gastrointestinal Microbiome/physiology ; Hydrogen-Ion Concentration ; Ileum/drug effects ; Ileum/microbiology ; Microbial Consortia/physiology ; Models, Biological ; Saccharomyces boulardii/drug effects ; Saccharomyces boulardii/growth & development ; Swine ; Temperature

Czasopismo naukowe

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Skocz do pozycji: 2.

Tytuł:

Choice of Differentiation Media Significantly Impacts Cell Lineage and Response to CFTR Modulators in Fully Differentiated Primary Cultures of Cystic Fibrosis Human Airway Epithelial Cells.

Autorzy:

Saint-Criq V; Biosciences Institute, University Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Delpiano L; Biosciences Institute, University Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Casement J; Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Onuora JC; Biosciences Institute, University Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Lin J; Biosciences Institute, University Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Gray MA; Biosciences Institute, University Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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Źródło:

Cells [Cells] 2020 Sep 21; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 21.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Transcriptome*
Cell Lineage/*drug effects
Culture Media/*pharmacology
Cystic Fibrosis Transmembrane Conductance Regulator/*genetics
Epithelial Cells/*drug effects
H(+)-K(+)-Exchanging ATPase/*genetics
Aminopyridines/pharmacology ; Benzodioxoles/pharmacology ; Cell Differentiation/drug effects ; Cell Lineage/genetics ; Culture Media/chemistry ; Cystic Fibrosis/genetics ; Cystic Fibrosis/metabolism ; Cystic Fibrosis/pathology ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Diffusion Chambers, Culture ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Gene Expression Regulation ; Goblet Cells/cytology ; Goblet Cells/drug effects ; Goblet Cells/metabolism ; H(+)-K(+)-Exchanging ATPase/metabolism ; Humans ; Hydrogen-Ion Concentration ; Primary Cell Culture ; Respiratory Mucosa/drug effects ; Respiratory Mucosa/metabolism ; Respiratory Mucosa/pathology ; Sequence Analysis, RNA

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Agar with embedded channels to study root growth.

Autorzy:

Aziz AA; Faculty of Engineering, Universiti Teknologi Brunei, Tungku Link, Gadong, BE1410, Brunei.
Lim KB; Faculty of Engineering, Universiti Teknologi Brunei, Tungku Link, Gadong, BE1410, Brunei.
Rahman EKA; Faculty of Engineering, Universiti Teknologi Brunei, Tungku Link, Gadong, BE1410, Brunei.
Nurmawati MH; Singapore Accreditation Council, 2 Fusionopolis Way, Singapore, 138634, Singapore.
Zuruzi AS; Department of Mechanical Engineering, College of Engineering, Alfaisal University, Riyadh, Kingdom of Saudi Arabia. .

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Źródło:

Scientific reports [Sci Rep] 2020 Aug 28; Vol. 10 (1), pp. 14231. Date of Electronic Publication: 2020 Aug 28.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Drug Delivery Systems/*methods
Nutrients/*pharmacology
Plant Roots/*growth & development
Agar/pharmacology ; Diffusion Chambers, Culture ; Germination/drug effects ; Mechanical Phenomena ; Nutrients/metabolism ; Vigna/growth & development

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

Broussoflavonol B from Broussonetia kazinoki Siebold Exerts Anti-Pancreatic Cancer Activity through Downregulating FoxM1.

Autorzy:

Jeong JH; Research Institute of Pharmaceutical Sciences and College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Ryu JH; Research Institute of Pharmaceutical Sciences and College of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 May 16; Vol. 25 (10). Date of Electronic Publication: 2020 May 16.

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Antineoplastic Agents, Phytogenic/*pharmacology
Broussonetia/*chemistry
Flavonols/*pharmacology
Forkhead Box Protein M1/*genetics
G1 Phase Cell Cycle Checkpoints/*drug effects
Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclin B1/genetics ; Cyclin B1/metabolism ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Diffusion Chambers, Culture ; Flavonols/isolation & purification ; Forkhead Box Protein M1/antagonists & inhibitors ; Forkhead Box Protein M1/metabolism ; G1 Phase Cell Cycle Checkpoints/genetics ; Humans ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/genetics ; Mitogen-Activated Protein Kinase 3/metabolism ; Pancreas/metabolism ; Pancreas/pathology ; Plant Bark/chemistry ; Plant Extracts/chemistry ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Signal Transduction ; Survivin/genetics ; Survivin/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

MIF inhibitor, ISO-1, attenuates human pancreatic cancer cell proliferation, migration and invasion in vitro, and suppresses xenograft tumour growth in vivo.

Autorzy:

Cheng B; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Wang Q; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Song Y; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Liu Y; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Liu Y; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Yang S; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Li D; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Zhang Y; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China.
Zhu C; Department of Emergency, the First Affiliated Hospital of Zhengzhou University, Henan, 450052, China. .

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Źródło:

Scientific reports [Sci Rep] 2020 Apr 21; Vol. 10 (1), pp. 6741. Date of Electronic Publication: 2020 Apr 21.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*drug therapy
Antineoplastic Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Intramolecular Oxidoreductases/*genetics
Isoxazoles/*pharmacology
Macrophage Migration-Inhibitory Factors/*genetics
Pancreatic Neoplasms/*drug therapy
Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Adenocarcinoma/pathology ; Animals ; Biological Assay ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Diffusion Chambers, Culture ; Female ; Humans ; Intramolecular Oxidoreductases/metabolism ; Macrophage Migration-Inhibitory Factors/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction ; Transcription Factor RelA/genetics ; Transcription Factor RelA/metabolism ; Tumor Burden/drug effects ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Xenograft Model Antitumor Assays

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1.

Autorzy:

Fezza M; Cancer and Metabolism Laboratory, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Moussa M; Cancer and Metabolism Laboratory, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Aoun R; Cancer and Metabolism Laboratory, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Haber R; Cancer and Metabolism Laboratory, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Hilal G; Cancer and Metabolism Laboratory, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.

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Źródło:

PloS one [PLoS One] 2019 Sep 30; Vol. 14 (9), pp. e0223252. Date of Electronic Publication: 2019 Sep 30 (Print Publication: 2019).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Hepatocytes/*metabolism
Intercellular Signaling Peptides and Proteins/*genetics
Transforming Growth Factor beta1/*genetics
Wnt Signaling Pathway/*genetics
Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Diffusion Chambers, Culture ; Hep G2 Cells ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Humans ; Inflammation ; Intercellular Signaling Peptides and Proteins/metabolism ; Intercellular Signaling Peptides and Proteins/pharmacology ; Proto-Oncogene Proteins c-mdm2/genetics ; Proto-Oncogene Proteins c-mdm2/metabolism ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Retinoblastoma Protein/genetics ; Retinoblastoma Protein/metabolism ; Telomerase/genetics ; Telomerase/metabolism ; Transforming Growth Factor beta1/antagonists & inhibitors ; Transforming Growth Factor beta1/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; alpha-Fetoproteins/genetics ; alpha-Fetoproteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 7.

Tytuł:

Clotrimazole Loaded Ufosomes for Topical Delivery: Formulation Development and In-Vitro Studies.

Autorzy:

Bolla PK; Department of Biomedical Engineering, College of Engineering, The University of Texas at El Paso, 500 W University Ave, El Paso, TX 79968, USA.
Meraz CA; Department of Biomedical Engineering, College of Engineering, The University of Texas at El Paso, 500 W University Ave, El Paso, TX 79968, USA.
Rodriguez VA; Department of Biomedical Engineering, College of Engineering, The University of Texas at El Paso, 500 W University Ave, El Paso, TX 79968, USA.
Deaguero I; Department of Biomedical Engineering, College of Engineering, The University of Texas at El Paso, 500 W University Ave, El Paso, TX 79968, USA.
Singh M; Department of Pharmaceutical Sciences, University of the Sciences in Philadelphia, Philadelphia, PA 19104, USA.
Yellepeddi VK; Division of Clinical Pharmacology, Department of Pediatrics, University of Utah, Salt Lake City, UT 84112, USA.; Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, University of Utah, Salt Lake City, UT 84112, USA.
Renukuntla J; Department of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, High Point, NC 27240, USA. .

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2019 Aug 29; Vol. 24 (17). Date of Electronic Publication: 2019 Aug 29.

Typ publikacji:

Journal Article

MeSH Terms:

Antifungal Agents/*metabolism
Clotrimazole/*metabolism
Delayed-Action Preparations/*chemistry
Drug Compounding/*methods
Liposomes/*chemistry
Administration, Cutaneous ; Antifungal Agents/chemistry ; Cadaver ; Cholesterol/chemistry ; Clotrimazole/chemistry ; Diffusion Chambers, Culture ; Humans ; Kinetics ; Oleic Acid/chemistry ; Particle Size ; Permeability ; Skin/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 8.

Tytuł:

Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D.

Autorzy:

Ezure T; Global Innovation Center, Shiseido, Yokohama, Japan.
Sugahara M; Global Innovation Center, Shiseido, Yokohama, Japan.
Amano S; Global Innovation Center, Shiseido, Yokohama, Japan.

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Źródło:

BioFactors (Oxford, England) [Biofactors] 2019 Jul; Vol. 45 (4), pp. 556-562. Date of Electronic Publication: 2019 Apr 26.

Typ publikacji:

Journal Article

MeSH Terms:

Extracellular Matrix/*metabolism
Fibroblasts/*metabolism
Matrix Metalloproteinase 1/*genetics
Cell Proliferation ; Cellular Senescence/drug effects ; Coculture Techniques ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Collagen Type I, alpha 1 Chain ; Complement Factor D/antagonists & inhibitors ; Complement Factor D/genetics ; Complement Factor D/metabolism ; Complement Factor D/pharmacology ; Diffusion Chambers, Culture ; Elastin/genetics ; Elastin/metabolism ; Extracellular Matrix/chemistry ; Extracellular Matrix/drug effects ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Gene Expression Regulation ; Humans ; Matrix Metalloproteinase 1/metabolism ; Primary Cell Culture ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 9.

Tytuł:

Made in Canada.

Autorzy:

Hyland N

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Źródło:

Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2013 Sep; Vol. 91 (9), pp. iii.

Typ publikacji:

Editorial; Comment

MeSH Terms:

Diffusion Chambers, Culture*
Probiotics*
Gastrointestinal Diseases/*therapy
Intestinal Mucosa/*metabolism
Intestinal Mucosa/*microbiology
Intestines/*microbiology
Membrane Transport Proteins/*metabolism
Animals ; Humans

Opinia redakcyjna

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Skocz do pozycji: 10.

Tytuł:

The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport.

Autorzy:

Lomasney KW; Department of Pharmacology and Therapeutics, Western Gateway Building, Western Road, University College Cork, Co. Cork, Ireland.
Hyland NP

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Źródło:

Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2013 Sep; Vol. 91 (9), pp. 663-70. Date of Electronic Publication: 2013 Mar 28.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't; Review

MeSH Terms:

Diffusion Chambers, Culture*
Probiotics*
Gastrointestinal Diseases/*therapy
Intestinal Mucosa/*metabolism
Intestinal Mucosa/*microbiology
Intestines/*microbiology
Membrane Transport Proteins/*metabolism
Animals ; Gastrointestinal Diseases/metabolism ; Gastrointestinal Diseases/microbiology ; Host-Pathogen Interactions ; Humans ; Intestinal Absorption ; Intestinal Secretions/metabolism ; Ion Transport ; Signal Transduction

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 11.

Tytuł:

Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration.

Autorzy:

Guo YC; Institute of Anatomy and Cell Biology, School of Medicine, National Yang Ming University, Peitou, Taipei, 112, Taiwan, Republic of China.
Chiu YH; Institute of Anatomy and Cell Biology, School of Medicine, National Yang Ming University, Peitou, Taipei, 112, Taiwan, Republic of China.
Chen CP; Division of High Risk Pregnancy, Mackay Memorial Hospital, Taipei, Taiwan, Republic of China.
Wang HS; Institute of Anatomy and Cell Biology, School of Medicine, National Yang Ming University, Peitou, Taipei, 112, Taiwan, Republic of China. .

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Źródło:

Stem cell research & therapy [Stem Cell Res Ther] 2018 Oct 25; Vol. 9 (1), pp. 281. Date of Electronic Publication: 2018 Oct 25.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Chemokine CXCL9/*genetics
Human Umbilical Vein Endothelial Cells/*drug effects
Interleukin-1beta/*pharmacology
Mesenchymal Stem Cells/*drug effects
RNA, Messenger/*genetics
Receptors, CXCR3/*genetics
Acetamides/pharmacology ; Chemokine CXCL9/metabolism ; Chemotaxis/drug effects ; Coculture Techniques ; Cycloheximide/pharmacology ; Diffusion Chambers, Culture ; Gene Expression Regulation ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Imidazoles/pharmacology ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; Pyridines/pharmacology ; Pyrimidinones/pharmacology ; RNA, Messenger/metabolism ; Receptors, CXCR3/antagonists & inhibitors ; Receptors, CXCR3/metabolism ; Umbilical Cord/cytology ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

LincRNA-p21 promotes mesenchymal stem cell migration capacity and survival through hypoxic preconditioning.

Autorzy:

Meng SS; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Xu XP; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Chang W; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Lu ZH; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Huang LL; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Xu JY; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Liu L; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Qiu HB; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Yang Y; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China.
Guo FM; Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, No.87, Dingjiaqiao Road, Gulou District, Nanjing, 210009, China. .

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Źródło:

Stem cell research & therapy [Stem Cell Res Ther] 2018 Oct 25; Vol. 9 (1), pp. 280. Date of Electronic Publication: 2018 Oct 25.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Cell Movement/*genetics
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Ischemic Preconditioning/*methods
Mesenchymal Stem Cells/*metabolism
RNA, Long Noncoding/*genetics
Animals ; Bone Marrow Cells/cytology ; Bone Marrow Cells/metabolism ; Cell Hypoxia ; Cell Survival ; Diffusion Chambers, Culture ; Disulfides/pharmacology ; Female ; Gene Expression Regulation ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Lentivirus/genetics ; Lentivirus/metabolism ; Mesenchymal Stem Cells/cytology ; Mice ; Mice, Inbred C57BL ; Primary Cell Culture ; RNA, Long Noncoding/antagonists & inhibitors ; RNA, Long Noncoding/metabolism ; Receptors, CXCR/genetics ; Receptors, CXCR/metabolism ; Receptors, CXCR4/genetics ; Receptors, CXCR4/metabolism ; Sulfonamides/pharmacology ; Von Hippel-Lindau Tumor Suppressor Protein/genetics ; Von Hippel-Lindau Tumor Suppressor Protein/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Calcium-induced chloride secretion is decreased by Resveratrol in ileal porcine tissue.

Autorzy:

Hoppe S; Department of Physiology, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173, Hannover, Germany.
Breves G; Department of Physiology, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173, Hannover, Germany.
Klinger S; Department of Physiology, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173, Hannover, Germany. .

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Źródło:

BMC research notes [BMC Res Notes] 2018 Oct 11; Vol. 11 (1), pp. 719. Date of Electronic Publication: 2018 Oct 11.

Typ publikacji:

Journal Article

MeSH Terms:

Calcium Chloride/*pharmacology
Chlorides/*metabolism
Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism
Ileum/*drug effects
Resveratrol/*pharmacology
Animals ; Carbachol/pharmacology ; Cyclic AMP/metabolism ; Diffusion Chambers, Culture ; Electric Conductivity ; Ileum/metabolism ; Ion Transport ; Jejunum/drug effects ; Jejunum/metabolism ; Organ Specificity ; Swine ; Tissue Culture Techniques

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 14.

Tytuł:

Pioglitazone restores the homocysteine‑impaired function of endothelial progenitor cells via the inhibition of the protein kinase C/NADPH oxidase pathway.

Autorzy:

Zhu J; Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Zhao Y; Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Yu L; Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Wang M; Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Li Q; Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Xu S; Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2018 Aug; Vol. 18 (2), pp. 1637-1643. Date of Electronic Publication: 2018 Jun 11.

Typ publikacji:

Journal Article

MeSH Terms:

Endothelial Progenitor Cells/*drug effects
Homocysteine/*antagonists & inhibitors
Hypoglycemic Agents/*pharmacology
NADPH Oxidase 2/*genetics
Phosphoproteins/*genetics
Thiazolidinediones/*pharmacology
Cell Adhesion/drug effects ; Cell Movement/drug effects ; Diffusion Chambers, Culture ; Endothelial Progenitor Cells/cytology ; Endothelial Progenitor Cells/metabolism ; Gene Expression Regulation ; Homocysteine/pharmacology ; Humans ; NADPH Oxidase 2/antagonists & inhibitors ; NADPH Oxidase 2/metabolism ; PPAR gamma/agonists ; PPAR gamma/genetics ; PPAR gamma/metabolism ; Phosphoproteins/antagonists & inhibitors ; Phosphoproteins/metabolism ; Pioglitazone ; Primary Cell Culture ; Protein Kinase C/genetics ; Protein Kinase C/metabolism ; Reactive Oxygen Species/agonists ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Signal Transduction

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 15.

Tytuł:

CTEN induces epithelial-mesenchymal transition (EMT) and metastasis in non small cell lung cancer cells.

Autorzy:

Lu X; Department of Oncology, The Jiangyin Hospital Affiliated to Medical College of Southeast University, Jiangyin, P.R.China.
Gao J; Department of Obstetrics and Gynecology, Jiangyin Hospital of Traditional Chinese Medicine, Jiangyin, P.R.China.
Zhang Y; Department of Oncology, The Jiangyin Hospital Affiliated to Medical College of Southeast University, Jiangyin, P.R.China.
Zhao T; Department of Oncology, The Jiangyin Hospital Affiliated to Medical College of Southeast University, Jiangyin, P.R.China.
Cai H; The 515th Hospital of PLA, Jiangyin, P.R.China.
Zhang T; Department of Oncology, The Jiangyin Hospital Affiliated to Medical College of Southeast University, Jiangyin, P.R.China.

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Źródło:

PloS one [PLoS One] 2018 Jul 09; Vol. 13 (7), pp. e0198823. Date of Electronic Publication: 2018 Jul 09 (Print Publication: 2018).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*genetics
Epithelial-Mesenchymal Transition/*genetics
Tensins/*genetics
Transforming Growth Factor beta1/*genetics
A549 Cells ; Antigens, CD/genetics ; Antigens, CD/metabolism ; Biomarkers, Tumor/metabolism ; Cadherins/genetics ; Cadherins/metabolism ; Cell Movement ; Diffusion Chambers, Culture ; Humans ; Plasmids/chemistry ; Plasmids/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Tensins/antagonists & inhibitors ; Tensins/metabolism ; Transfection ; Transforming Growth Factor beta1/metabolism ; Vimentin/genetics ; Vimentin/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 16.

Tytuł:

An integrated environmental perfusion chamber and heating system for long-term, high resolution imaging of living cells.

Autorzy:

Hing WA; Department of Anatomy, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Poole CA
Jensen CG
Watson M

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Źródło:

Journal of microscopy [J Microsc] 2000 Aug; Vol. 199 (Pt 2), pp. 90-5.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Diffusion Chambers, Culture*
Microscopy, Video/*methods
Animals ; Cartilage, Articular/cytology ; Cell Survival ; Cells, Cultured ; Dogs ; Epithelial Cells/cytology ; Haplorhini ; Heating ; Humans ; Hydrogen-Ion Concentration ; Microscopy, Video/instrumentation ; Osmolar Concentration ; Perfusion/instrumentation ; Perfusion/methods

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 17.

Tytuł:

Effect of a synthetic inhibitor of urokinase plasminogen activator on the migration and invasion of human cervical cancer cells in vitro.

Autorzy:

Wang X; Laboratory of Gynecologic Oncology, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Jiang Z; Department of Gynecology, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, Fujian 361009, P.R. China.
An J; Laboratory of Gynecologic Oncology, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Mao X; Laboratory of Gynecologic Oncology, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Lin F; Laboratory of Gynecologic Oncology, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Sun P; Laboratory of Gynecologic Oncology, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2018 Mar; Vol. 17 (3), pp. 4273-4280. Date of Electronic Publication: 2018 Jan 09.

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Amiloride/*pharmacology
Antineoplastic Agents/*pharmacology
Epithelial Sodium Channel Blockers/*pharmacology
Matrix Metalloproteinase 2/*genetics
Urokinase-Type Plasminogen Activator/*genetics
Cell Movement/drug effects ; Collagen/chemistry ; Diffusion Chambers, Culture ; Drug Combinations ; HeLa Cells ; Humans ; Laminin/chemistry ; Matrix Metalloproteinase 2/metabolism ; Proteoglycans/chemistry ; RNA, Messenger/antagonists & inhibitors ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Urokinase Plasminogen Activator/genetics ; Receptors, Urokinase Plasminogen Activator/metabolism ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Signal Transduction ; Urokinase-Type Plasminogen Activator/antagonists & inhibitors ; Urokinase-Type Plasminogen Activator/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 18.

Tytuł:

MicroRNA‑340 inhibits tumor cell proliferation, migration and invasion, and induces apoptosis in hepatocellular carcinoma.

Autorzy:

Wang Z; National Key Clinical Department, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400000, P.R. China.
Song D; National Key Clinical Department, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400000, P.R. China.
Huang P; National Key Clinical Department, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing 400000, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2017 Nov; Vol. 16 (5), pp. 7649-7656. Date of Electronic Publication: 2017 Sep 21.

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Carcinoma, Hepatocellular/*genetics
Liver Neoplasms/*genetics
MicroRNAs/*genetics
S-Phase Kinase-Associated Proteins/*genetics
Adult ; Aged ; Antagomirs/genetics ; Antagomirs/metabolism ; Apoptosis ; Base Sequence ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Diffusion Chambers, Culture ; Female ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Male ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/metabolism ; Middle Aged ; Neoplasm Staging ; S-Phase Kinase-Associated Proteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 19.

Tytuł:

Do model polymer therapeutics sufficiently diffuse through articular cartilage to be a viable therapeutic route?

Autorzy:

Powell A; a School of Biosciences , Cardiff University , Cardiff , UK.
Caterson B; a School of Biosciences , Cardiff University , Cardiff , UK.
Hughes C; a School of Biosciences , Cardiff University , Cardiff , UK.
Paul A; b School of Chemistry , Cardiff University , Cardiff , UK.
James C; b School of Chemistry , Cardiff University , Cardiff , UK.
Hopkins S; b School of Chemistry , Cardiff University , Cardiff , UK.
Mansour O; c Department of Pharmaceutical, Chemical and Environmental Sciences, Faculty of Engineering and Science , University of Greenwich , Kent , UK.
Griffiths P; c Department of Pharmaceutical, Chemical and Environmental Sciences, Faculty of Engineering and Science , University of Greenwich , Kent , UK.

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Źródło:

Journal of drug targeting [J Drug Target] 2017 Nov - Dec; Vol. 25 (9-10), pp. 919-926. Date of Electronic Publication: 2017 Sep 21.

Typ publikacji:

Journal Article

MeSH Terms:

Biocompatible Materials/*metabolism
Cartilage, Articular/*metabolism
Polymers/*metabolism
Animals ; Arthritis/drug therapy ; Arthritis/metabolism ; Biocompatible Materials/therapeutic use ; Cattle ; Cells, Cultured ; Dextrins/metabolism ; Dextrins/therapeutic use ; Diffusion Chambers, Culture ; Polymers/therapeutic use ; Synovial Fluid/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

MiR-137 inhibited cell proliferation and migration of vascular smooth muscle cells via targeting IGFBP-5 and modulating the mTOR/STAT3 signaling.

Autorzy:

Pan J; Clinical Medical College, Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Li K; Department of Cardiology, the First Affiliated Hospital of Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Huang W; Clinical Medical College, Xi'an Medical University, Xi'an City, Shaanxi Province, China.
Zhang X; Clinical Medical College, Xi'an Medical University, Xi'an City, Shaanxi Province, China.

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Źródło:

PloS one [PLoS One] 2017 Oct 10; Vol. 12 (10), pp. e0186245. Date of Electronic Publication: 2017 Oct 10 (Print Publication: 2017).

Typ publikacji:

Journal Article

MeSH Terms:

Signal Transduction*
Insulin-Like Growth Factor Binding Protein 5/*genetics
MicroRNAs/*genetics
Myocytes, Smooth Muscle/*metabolism
STAT3 Transcription Factor/*genetics
TOR Serine-Threonine Kinases/*genetics
Aorta/cytology ; Aorta/drug effects ; Aorta/metabolism ; Base Sequence ; Becaplermin ; Binding Sites ; Cell Line ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Computational Biology ; Diffusion Chambers, Culture ; Gene Expression Regulation ; Genes, Reporter ; Humans ; Insulin-Like Growth Factor Binding Protein 5/metabolism ; Luciferases/genetics ; Luciferases/metabolism ; MicroRNAs/metabolism ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/drug effects ; Proto-Oncogene Proteins c-sis/pharmacology ; STAT3 Transcription Factor/metabolism ; TOR Serine-Threonine Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 21.

Tytuł:

Metabolically conditioned media derived from bone marrow stromal cells or human skin fibroblasts act as effective chemoattractants for mesenchymal stem cells.

Autorzy:

Gabrielyan A; Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Neumann E; Department of Internal Medicine and Rheumatology, Justus-Liebig-University Gießen and Kerckhoff-Klinik Bad Nauheim, Benekestraße 2-8, 61231, Bad Nauheim, Germany.
Gelinsky M; Centre for Translational Bone, Joint and Soft Tissue Research, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Rösen-Wolff A; Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany. .

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Źródło:

Stem cell research & therapy [Stem Cell Res Ther] 2017 Sep 29; Vol. 8 (1), pp. 212. Date of Electronic Publication: 2017 Sep 29.

Typ publikacji:

Journal Article

MeSH Terms:

Angiogenic Proteins/*pharmacology
Bone Marrow Cells/*metabolism
Chemotactic Factors/*pharmacology
Culture Media, Conditioned/*chemistry
Fibroblasts/*metabolism
Mesenchymal Stem Cells/*drug effects
Angiogenic Proteins/biosynthesis ; Angiogenic Proteins/isolation & purification ; Angiogenic Proteins/metabolism ; Biological Assay ; Bone Marrow Cells/cytology ; Cell Hypoxia ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Chemotactic Factors/biosynthesis ; Chemotactic Factors/isolation & purification ; Chemotactic Factors/metabolism ; Chemotaxis/drug effects ; Chemotaxis/physiology ; Culture Media, Conditioned/pharmacology ; Diffusion Chambers, Culture ; Fibroblasts/cytology ; Foreskin/cytology ; Foreskin/metabolism ; Humans ; Male ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/physiology ; Neovascularization, Physiologic/drug effects ; Primary Cell Culture

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 22.

Tytuł:

Emulsion-Based Intradermal Delivery of Melittin in Rats.

Autorzy:

Han SM; Rural Development Administration, National Academy of Agricultural Science, Wanju, Chonbuk 55365, Korea. .
Kim SG; Rural Development Administration, National Academy of Agricultural Science, Wanju, Chonbuk 55365, Korea. .
Pak SC; School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW 2795, Australia. .

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2017 May 19; Vol. 22 (5). Date of Electronic Publication: 2017 May 19.

Typ publikacji:

Journal Article

MeSH Terms:

Dermis/*metabolism
Epidermis/*metabolism
Melitten/*pharmacokinetics
Skin Absorption/*physiology
Administration, Cutaneous ; Animals ; Dermis/drug effects ; Diffusion Chambers, Culture ; Emulsions ; Epidermis/drug effects ; Excipients/chemistry ; Excipients/pharmacology ; Male ; Pyrrolidinones/chemistry ; Pyrrolidinones/pharmacology ; Rats ; Rats, Sprague-Dawley

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 23.

Tytuł:

Mucoadhesive niosomal in situ gel for ocular tissue targeting: in vitro and in vivo evaluation of lomefloxacin hydrochloride.

Autorzy:

Abdelbary A; a Department of Pharmaceutics, Faculty of Pharmacy , Cairo University , Cairo , Egypt.
Salem HF; b Department of Pharmaceutics, Faculty of Pharmacy , Beni-Suef University , Beni-Suef , Egypt.
Khallaf RA; b Department of Pharmaceutics, Faculty of Pharmacy , Beni-Suef University , Beni-Suef , Egypt.
Ali AM; b Department of Pharmaceutics, Faculty of Pharmacy , Beni-Suef University , Beni-Suef , Egypt.; c Department of Pharmaceutics, Faculty of Pharmacy , Taif University , Taif , KSA.

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Źródło:

Pharmaceutical development and technology [Pharm Dev Technol] 2017 May; Vol. 22 (3), pp. 409-417. Date of Electronic Publication: 2016 Aug 31.

Typ publikacji:

Journal Article

MeSH Terms:

Anti-Bacterial Agents/*administration & dosage
Cornea/*metabolism
Drug Compounding/*methods
Fluoroquinolones/*administration & dosage
Gels/*chemistry
Surface-Active Agents/*chemistry
Animals ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/pharmacokinetics ; Anti-Bacterial Agents/pharmacology ; Bacillus subtilis/drug effects ; Biological Availability ; Cattle ; Cornea/drug effects ; Diffusion Chambers, Culture ; Drug Stability ; Escherichia coli/drug effects ; Fluoroquinolones/adverse effects ; Fluoroquinolones/pharmacokinetics ; Fluoroquinolones/pharmacology ; In Vitro Techniques ; Liposomes ; Microbial Sensitivity Tests ; Particle Size ; Permeability ; Rabbits ; Tissue Distribution

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

Optimization of nanostructured lipid carriers for topical delivery of nimesulide using Box-Behnken design approach.

Autorzy:

Moghddam SM; a Department of Pharmaceutics, Faculty of Pharmacy , Jamia Hamdard (Hamdard University) , New Delhi , India.
Ahad A; b Department of Pharmaceutics, College of Pharmacy , King Saud University , Riyadh , Saudi Arabia.
Aqil M; a Department of Pharmaceutics, Faculty of Pharmacy , Jamia Hamdard (Hamdard University) , New Delhi , India.
Imam SS; c Glocal School of Pharmacy , Glocal University , Saharanpur , Uttar Pradesh , India.
Sultana Y; a Department of Pharmaceutics, Faculty of Pharmacy , Jamia Hamdard (Hamdard University) , New Delhi , India.

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Źródło:

Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2017 May; Vol. 45 (3), pp. 617-624. Date of Electronic Publication: 2016 Apr 06.

Typ publikacji:

Journal Article

MeSH Terms:

Drug Carriers*
Anti-Inflammatory Agents, Non-Steroidal/*chemistry
Drug Compounding/*methods
Nanoparticles/*chemistry
Skin/*metabolism
Sulfonamides/*chemistry
Administration, Cutaneous ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/metabolism ; Diffusion Chambers, Culture ; Factor Analysis, Statistical ; Glycerides/chemistry ; Linseed Oil/chemistry ; Nanoparticles/ultrastructure ; Oleic Acid/chemistry ; Olive Oil/chemistry ; Rats ; Skin/drug effects ; Solubility ; Sulfonamides/metabolism ; Tissue Culture Techniques

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 25.

Tytuł:

Skin permeation of econazole nitrate formulated in an enhanced hydrophilic multiple emulsion.

Autorzy:

Suñer-Carbó J; Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Boix-Montañés A; Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Halbaut-Bellowa L; Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Velázquez-Carralero N; Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Zamarbide-Ledesma J; Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Bozal-de-Febrer N; Department of Microbiology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Calpena-Campmany AC; Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.

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Źródło:

Mycoses [Mycoses] 2017 Mar; Vol. 60 (3), pp. 166-177. Date of Electronic Publication: 2016 Oct 20.

Typ publikacji:

Journal Article

MeSH Terms:

Skin Absorption*
Antifungal Agents/*pharmacokinetics
Econazole/*pharmacokinetics
Skin/*metabolism
Administration, Cutaneous ; Antifungal Agents/therapeutic use ; Candida/drug effects ; Diffusion Chambers, Culture ; Drug Compounding ; Drug Liberation ; Drug Stability ; Drug Storage ; Econazole/therapeutic use ; Emulsions ; Humans ; Hydrophobic and Hydrophilic Interactions ; Skin/microbiology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 26.

Tytuł:

A Microfabricated 96-Well 3D Assay Enabling High-Throughput Quantification of Cellular Invasion Capabilities.

Autorzy:

Hao R; State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P.R. China.
Wei Y; State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P.R. China.
Li C; Microelectronics Equipment Research and Development Center, Institute of Microelectronics of Chinese Academy of Sciences, Beijing 100029, P.R. China.
Chen F; Department of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Chen D; State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P.R. China.
Zhao X; Department of Cellular and Molecular Biology, Beijing Chest Hospital, Capital Medical University, Beijing 101149, P.R. China.
Luan S; Department of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Fan B; State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P.R. China.
Guo W; Department of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Wang J; State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P.R. China.
Chen J; State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, P.R. China.

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Źródło:

Scientific reports [Sci Rep] 2017 Feb 27; Vol. 7, pp. 43390. Date of Electronic Publication: 2017 Feb 27.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Biological Assay*
Cell Movement*
Cell Culture Techniques/*methods
Microtechnology/*methods
A549 Cells ; Cell Culture Techniques/instrumentation ; Cell Line, Tumor ; Collagen/chemistry ; Diffusion Chambers, Culture ; Dimethylpolysiloxanes/chemistry ; Extracellular Matrix/chemistry ; Fibronectins/chemistry ; Humans ; Microtechnology/instrumentation ; Organ Specificity ; Polyesters/chemistry ; Polyethylene Glycols/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 27.

Tytuł:

A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis.

Autorzy:

Takemoto A; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Okitaka M; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8561, Japan.
Takagi S; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Takami M; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Sato S; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Nishio M; Department of Thoracic Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Okumura S; Department of Thoracic Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Fujita N; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8561, Japan.

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Źródło:

Scientific reports [Sci Rep] 2017 Feb 08; Vol. 7, pp. 42186. Date of Electronic Publication: 2017 Feb 08.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Epithelial-Mesenchymal Transition*
Gene Expression Regulation, Neoplastic*
Carcinoma, Small Cell/*genetics
Lung Neoplasms/*genetics
Membrane Glycoproteins/*genetics
Transforming Growth Factor beta/*genetics
A549 Cells ; Animals ; Antibodies, Neutralizing/pharmacology ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Blood Platelets/pathology ; Carcinoma, Small Cell/drug therapy ; Carcinoma, Small Cell/metabolism ; Carcinoma, Small Cell/pathology ; Cell Movement/drug effects ; Diffusion Chambers, Culture ; Female ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Membrane Glycoproteins/antagonists & inhibitors ; Membrane Glycoproteins/metabolism ; Mice ; Mice, Inbred ICR ; Neoplasm Invasiveness ; Platelet Aggregation/drug effects ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Transforming Growth Factor beta/antagonists & inhibitors ; Transforming Growth Factor beta/metabolism ; Tumor Microenvironment

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 28.

Tytuł:

Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology.

Autorzy:

Pentek T; School of Pharmacy, Concordia University Wisconsin, 12800 N. Lake Shore Drive, Mequon, WI 53097, USA. .
Newenhouse E; School of Pharmacy, Concordia University Wisconsin, 12800 N. Lake Shore Drive, Mequon, WI 53097, USA. .
O'Brien B; School of Pharmacy, Concordia University Wisconsin, 12800 N. Lake Shore Drive, Mequon, WI 53097, USA. .
Chauhan AS; School of Pharmacy, Concordia University Wisconsin, 12800 N. Lake Shore Drive, Mequon, WI 53097, USA. .; School of Pharmacy, Medical College of Wisconsin, Milwaukee, 8701 W. Watertown Plank Road, Milwaukee, WI 53226, USA. .

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2017 Jan 14; Vol. 22 (1). Date of Electronic Publication: 2017 Jan 14.

Typ publikacji:

Journal Article

MeSH Terms:

Antioxidants/*pharmacokinetics
Dendrimers/*chemistry
Skin/*metabolism
Skin Cream/*pharmacokinetics
Stilbenes/*pharmacokinetics
Animals ; Antioxidants/chemistry ; Diffusion Chambers, Culture ; Drug Stability ; Humans ; Hydrogen-Ion Concentration ; Permeability ; Polysorbates/chemistry ; Rats ; Resveratrol ; Skin/drug effects ; Skin Cream/chemistry ; Solubility ; Stilbenes/chemistry ; Water/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 29.

Tytuł:

ZHX1 Promotes the Proliferation, Migration and Invasion of Cholangiocarcinoma Cells.

Autorzy:

Kwon RJ; Department of Anatomy, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.; Gene & Therapy Research Center for Vessel-associated Diseases, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Han ME; Department of Anatomy, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.; Gene & Therapy Research Center for Vessel-associated Diseases, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Kim JY; Department of Anatomy, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.; Gene & Therapy Research Center for Vessel-associated Diseases, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Liu L; Department of Anatomy, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.; Gene & Therapy Research Center for Vessel-associated Diseases, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Kim YH; Department of Anatomy, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.; Gene & Therapy Research Center for Vessel-associated Diseases, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Jung JS; Department of Physiology, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Oh SO; Department of Anatomy, School of Medicine, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.; Gene & Therapy Research Center for Vessel-associated Diseases, Pusan National University, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.

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Źródło:

PloS one [PLoS One] 2016 Nov 11; Vol. 11 (11), pp. e0165516. Date of Electronic Publication: 2016 Nov 11 (Print Publication: 2016).

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Bile Duct Neoplasms/*genetics
Cholangiocarcinoma/*genetics
Early Growth Response Protein 1/*genetics
Homeodomain Proteins/*genetics
Transcription Factors/*genetics
Bile Duct Neoplasms/metabolism ; Bile Duct Neoplasms/pathology ; Bile Ducts, Intrahepatic/metabolism ; Bile Ducts, Intrahepatic/pathology ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cholangiocarcinoma/metabolism ; Cholangiocarcinoma/pathology ; Collagen/chemistry ; Diffusion Chambers, Culture ; Drug Combinations ; Early Growth Response Protein 1/metabolism ; Homeodomain Proteins/antagonists & inhibitors ; Homeodomain Proteins/metabolism ; Humans ; Laminin/chemistry ; Proteoglycans/chemistry ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Transcription Factors/antagonists & inhibitors ; Transcription Factors/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 30.

Tytuł:

Did you know? The Ussing chamber origin.

Autorzy:

Persson PB; Institut für vegetative Physiologie, Charité-Universitaetsmedizin, Berlin, Germany. .

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Źródło:

Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2016 Oct; Vol. 218 (2), pp. 67. Date of Electronic Publication: 2016 Apr 30.

Typ publikacji:

Editorial; Historical Article

MeSH Terms:

Diffusion Chambers, Culture/*history
Animals ; History, 20th Century ; Humans ; Membranes/physiology ; Permeability

Opinia redakcyjna

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 31.

Tytuł:

MicroRNA Profiling of the Effect of the Heptapeptide Angiotensin-(1-7) in A549 Lung Tumor Cells Reveals a Role for miRNA149-3p in Cellular Migration Processes.

Autorzy:

Silva Bde O; Núcleo de Pesquisa em Biologia, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
Lima KF; Institute of Chemistry, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Araraquara, SP, Brazil.
Gonçalves LR; Molecular Biology Laboratory, Departament of Biology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Rio Claro, SP, Brazil.
Silveira MB; Molecular Biology Laboratory, Departament of Biology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Rio Claro, SP, Brazil.
Moraes KC; Molecular Biology Laboratory, Departament of Biology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Rio Claro, SP, Brazil.

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Źródło:

PloS one [PLoS One] 2016 Sep 06; Vol. 11 (9), pp. e0162094. Date of Electronic Publication: 2016 Sep 06 (Print Publication: 2016).

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
MicroRNAs/*genetics
A549 Cells ; Angiotensin I ; Cell Movement/drug effects ; Diffusion Chambers, Culture ; Gene Expression Profiling ; Humans ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/metabolism ; Oligoribonucleotides, Antisense/genetics ; Oligoribonucleotides, Antisense/metabolism ; Peptide Fragments

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 32.

Tytuł:

Cyclic Dipeptide Shuttles as a Novel Skin Penetration Enhancement Approach: Preliminary Evaluation with Diclofenac.

Autorzy:

Mohammed Y; School of Pharmacy, Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia.; Therapeutics Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, Queensland, Australia.
Teixidó M; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Science and Technology Institute (BIST), Barcelona, Spain.
Namjoshi S; Therapeutics Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, Queensland, Australia.
Giralt E; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Science and Technology Institute (BIST), Barcelona, Spain.
Benson H; School of Pharmacy, Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia.

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Źródło:

PloS one [PLoS One] 2016 Aug 22; Vol. 11 (8), pp. e0160973. Date of Electronic Publication: 2016 Aug 22 (Print Publication: 2016).

Typ publikacji:

Journal Article

MeSH Terms:

Drug Carriers*
Dipeptides/*metabolism
Epidermis/*metabolism
Gene Products, tat/*metabolism
Peptides, Cyclic/*metabolism
Piperazines/*chemistry
Abdominoplasty ; Adult ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Cyclooxygenase Inhibitors/metabolism ; Cyclooxygenase Inhibitors/pharmacology ; Diclofenac/metabolism ; Diclofenac/pharmacology ; Diffusion Chambers, Culture ; Dipeptides/chemistry ; Epidermis/drug effects ; Female ; Gene Expression ; Gene Products, tat/chemistry ; Humans ; Middle Aged ; Peptides, Cyclic/chemistry ; Permeability ; Solid-Phase Synthesis Techniques ; Tissue Culture Techniques

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 33.

Tytuł:

The trans-well coculture of human synovial mesenchymal stem cells with chondrocytes leads to self-organization, chondrogenic differentiation, and secretion of TGFβ.

Autorzy:

Kubosch EJ; Department of Orthopedics and Trauma Surgery, Albert-Ludwigs University Medical Center Freiburg, Freiburg, Germany.
Heidt E; Department of Orthopedics and Trauma Surgery, Albert-Ludwigs University Medical Center Freiburg, Freiburg, Germany.
Bernstein A; Department of Orthopedics and Trauma Surgery, Albert-Ludwigs University Medical Center Freiburg, Freiburg, Germany.
Böttiger K; Department of Orthopedics and Trauma Surgery, Albert-Ludwigs University Medical Center Freiburg, Freiburg, Germany.
Schmal H; Department of Orthopaedics and Traumatology, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark. .; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. .

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Źródło:

Stem cell research & therapy [Stem Cell Res Ther] 2016 Apr 26; Vol. 7 (1), pp. 64. Date of Electronic Publication: 2016 Apr 26.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Chondrocytes/*pathology
Mesenchymal Stem Cells/*pathology
RNA, Messenger/*genetics
Transforming Growth Factor beta/*genetics
Adult ; Aged ; Aggrecans/genetics ; Aggrecans/metabolism ; Arthroplasty, Replacement, Knee ; Cell Aggregation ; Cell Differentiation ; Chondrocytes/metabolism ; Coculture Techniques ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Collagen Type II/genetics ; Collagen Type II/metabolism ; Diffusion Chambers, Culture ; Female ; Gene Expression Regulation ; Humans ; Joint Capsule/metabolism ; Joint Capsule/pathology ; Joint Capsule/surgery ; Knee Joint/metabolism ; Knee Joint/pathology ; Knee Joint/surgery ; Male ; Mesenchymal Stem Cells/metabolism ; Middle Aged ; RNA, Messenger/metabolism ; Signal Transduction ; Transforming Growth Factor beta/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 34.

Tytuł:

K+ Channel Inhibition Differentially Regulates Migration of Intestinal Epithelial Cells in Inflamed vs. Non-Inflamed Conditions in a PI3K/Akt-Mediated Manner.

Autorzy:

Zundler S; Department of Internal Medicine I, Regensburg University Medical Center, Regensburg, Germany.; Department of Medicine 1, University of Erlangen-Nuremberg, Kussmaul Campus for Medical Research & Translational Research Center, Erlangen, Germany.
Caioni M; Department of Internal Medicine I, Regensburg University Medical Center, Regensburg, Germany.
Müller M; Department of Internal Medicine I, Regensburg University Medical Center, Regensburg, Germany.
Strauch U; Department of Internal Medicine I, Regensburg University Medical Center, Regensburg, Germany.
Kunst C; Department of Internal Medicine I, Regensburg University Medical Center, Regensburg, Germany.
Woelfel G; Department of Internal Medicine I, Regensburg University Medical Center, Regensburg, Germany.

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Źródło:

PloS one [PLoS One] 2016 Jan 29; Vol. 11 (1), pp. e0147736. Date of Electronic Publication: 2016 Jan 29 (Print Publication: 2016).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Epithelial Cells/*metabolism
Inflammatory Bowel Diseases/*metabolism
Intermediate-Conductance Calcium-Activated Potassium Channels/*antagonists & inhibitors
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Animals, Newborn ; Biological Assay ; Cell Line ; Cell Movement/drug effects ; Diffusion Chambers, Culture ; Epidermal Growth Factor/pharmacology ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Gene Expression Regulation ; HT29 Cells ; Humans ; Ileum/cytology ; Ileum/drug effects ; Ileum/metabolism ; Inflammatory Bowel Diseases/genetics ; Inflammatory Bowel Diseases/pathology ; Interferon-gamma/pharmacology ; Intermediate-Conductance Calcium-Activated Potassium Channels/genetics ; Intermediate-Conductance Calcium-Activated Potassium Channels/metabolism ; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 3/genetics ; Mitogen-Activated Protein Kinase 3/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphoinositide-3 Kinase Inhibitors ; Phosphorylation/drug effects ; Primary Cell Culture ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/genetics ; Rats ; Signal Transduction ; Wound Healing/drug effects

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 35.

Tytuł:

Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4.

Autorzy:

Grottke A; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Ewald F; Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Lange T; Center for Experimental Medicine, Department of Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Nörz D; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Herzberger C; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Bach J; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Grabinski N; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Gräser L; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Höppner F; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Nashan B; Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Schumacher U; Center for Experimental Medicine, Department of Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Jücker M; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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Źródło:

PloS one [PLoS One] 2016 Jan 07; Vol. 11 (1), pp. e0146370. Date of Electronic Publication: 2016 Jan 07 (Print Publication: 2016).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*genetics
Lung Neoplasms/*genetics
Proto-Oncogene Proteins c-akt/*genetics
S100 Proteins/*genetics
Triple Negative Breast Neoplasms/*genetics
Adenocarcinoma/metabolism ; Adenocarcinoma/secondary ; Animals ; Cell Line, Tumor ; Cell Movement ; Chemotaxis/genetics ; Diffusion Chambers, Culture ; Female ; Gene Silencing ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/secondary ; Mice ; Neoplasm Invasiveness ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; S100 Calcium-Binding Protein A4 ; S100 Proteins/agonists ; S100 Proteins/metabolism ; Signal Transduction ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/pathology ; Xenograft Model Antitumor Assays

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 36.

Tytuł:

Development of ibuprofen nanoliposome for transdermal delivery: Physical characterization, in vitro/in vivo studies, and anti-inflammatory activity.

Autorzy:

Gaur PK; a Department of Pharmaceutics , I.T.S. Paramedical College (Pharmacy) , Muradnagar, Ghaziabad , U.P. , India.
Bajpai M; a Department of Pharmaceutics , I.T.S. Paramedical College (Pharmacy) , Muradnagar, Ghaziabad , U.P. , India.
Mishra S; b Department of Pharmacognosy and Phytochemistry , Jamia Hamdard , New Delhi , India.
Verma A; c Department of Pharmaceutics , School of Pharmaceutical Sciences, IFTM University , Moradabad , India.

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Źródło:

Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2016; Vol. 44 (1), pp. 370-5. Date of Electronic Publication: 2014 Sep 11.

Typ publikacji:

Journal Article

MeSH Terms:

Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Delayed-Action Preparations/*pharmacology
Edema/*drug therapy
Ibuprofen/*pharmacology
Liposomes/*chemistry
Acrylates/chemistry ; Administration, Cutaneous ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacokinetics ; Area Under Curve ; Carrageenan ; Cholesterol/chemistry ; Delayed-Action Preparations/pharmacokinetics ; Diffusion Chambers, Culture ; Drug Compounding ; Drug Liberation ; Edema/chemically induced ; Edema/metabolism ; Edema/pathology ; Gels ; Hindlimb/drug effects ; Hindlimb/pathology ; Humans ; Ibuprofen/pharmacokinetics ; Organophosphates/chemistry ; Permeability ; Phosphatidylcholines/chemistry ; Rats ; Rats, Wistar ; Skin/drug effects ; Skin/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 37.

Tytuł:

Permeability study of ciprofloxacin from ultra-thin nanofibrous film through various mucosal membranes.

Autorzy:

Modgill V; a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
Garg T; a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
Goyal AK; a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.
Rath G; a Department of Pharmaceutics , ISF College of Pharmacy , Moga , Punjab , India.

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Źródło:

Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2016; Vol. 44 (1), pp. 122-7. Date of Electronic Publication: 2014 Jun 10.

Typ publikacji:

Journal Article

MeSH Terms:

Anti-Bacterial Agents/*pharmacokinetics
Ciprofloxacin/*pharmacokinetics
Delayed-Action Preparations/*chemistry
Drug Carriers/*chemistry
Nanofibers/*chemistry
Animals ; Cell Membrane Permeability ; Diffusion Chambers, Culture ; Drug Compounding ; Drug Liberation ; Eye/metabolism ; Goats ; Intestinal Mucosa/metabolism ; Mouth Mucosa/metabolism ; Nanofibers/ultrastructure ; Organ Specificity ; Polyvinyl Alcohol/chemistry ; Rectum/metabolism ; Skin/metabolism ; Trachea/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 38.

Tytuł:

Influence of selected variables on fabrication of Triamcinolone acetonide loaded solid lipid nanoparticles for topical treatment of dermal disorders.

Autorzy:

Pradhan M; a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
Singh D; a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.
Singh MR; a Pharmaceutical Biotechnology Laboratory, University Institute of Pharmacy, Pt. Ravishankar Shukla University , Raipur , Chhattisgarh , India.

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Źródło:

Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2016; Vol. 44 (1), pp. 392-400. Date of Electronic Publication: 2014 Sep 17.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Anti-Inflammatory Agents/*pharmacokinetics
Delayed-Action Preparations/*pharmacokinetics
Nanoparticles/*chemistry
Skin/*drug effects
Triamcinolone Acetonide/*pharmacology
Acrylates/chemistry ; Administration, Cutaneous ; Animals ; Anti-Inflammatory Agents/pharmacology ; Delayed-Action Preparations/pharmacology ; Diffusion Chambers, Culture ; Diglycerides/chemistry ; Drug Compounding ; Drug Liberation ; Drug Stability ; Fatty Acids/chemistry ; Gels ; Goats ; Nanoparticles/ultrastructure ; Particle Size ; Permeability ; Skin/metabolism ; Skin Absorption ; Stearic Acids/chemistry ; Triamcinolone Acetonide/pharmacokinetics

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 39.

Tytuł:

Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells.

Autorzy:

Sui Y; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Wu F; Department of Gynecology and Obstetrics, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Lv J; Department of Radiology, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Li H; Department of Dermatology, Jilin University Bethune First Hospital, Changchun, P. R. China.
Li X; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Du Z; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Sun M; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Zheng Y; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Yang L; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Zhong L; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Zhang X; Department of Thoracic Surgery, Jilin University Bethune Second Hospital, Changchun, P. R. China.
Zhang G; Key Laboratory for Molecular and Chemical Genetics of Critical Human Diseases of Jilin Province, Jilin University Bethune Second Hospital, Changchun, P. R. China.

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Źródło:

PloS one [PLoS One] 2015 Dec 11; Vol. 10 (12), pp. e0144715. Date of Electronic Publication: 2015 Dec 11 (Print Publication: 2015).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Antineoplastic Agents/*pharmacology
Calcium Channel Blockers/*pharmacology
Chloride Channels/*genetics
Diterpenes/*pharmacology
Epithelial Cells/*drug effects
Neoplasm Proteins/*genetics
Animals ; Anoctamin-1 ; Calcium/metabolism ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Chloride Channels/antagonists & inhibitors ; Chloride Channels/metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Diffusion Chambers, Culture ; Dose-Response Relationship, Drug ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Gene Expression ; Humans ; Ion Transport ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/metabolism ; Organ Specificity ; Patch-Clamp Techniques ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Inbred F344 ; Thyroid Gland ; Transgenes

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 40.

Tytuł:

SOX18 Is a Novel Target Gene of Hedgehog Signaling in Cervical Carcinoma Cell Lines.

Autorzy:

Petrovic I; Laboratory for Human Molecular Genetics, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, P.O.BOX 23, 11000 Belgrade, Serbia.
Milivojevic M; Laboratory for Human Molecular Genetics, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, P.O.BOX 23, 11000 Belgrade, Serbia.
Popovic J; Laboratory for Human Molecular Genetics, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, P.O.BOX 23, 11000 Belgrade, Serbia.
Schwirtlich M; Laboratory for Human Molecular Genetics, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, P.O.BOX 23, 11000 Belgrade, Serbia.
Rankovic B; Laboratory for Human Molecular Genetics, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, P.O.BOX 23, 11000 Belgrade, Serbia.
Stevanovic M; Laboratory for Human Molecular Genetics, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, P.O.BOX 23, 11000 Belgrade, Serbia.

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Źródło:

PloS one [PLoS One] 2015 Nov 20; Vol. 10 (11), pp. e0143591. Date of Electronic Publication: 2015 Nov 20 (Print Publication: 2015).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Signal Transduction*
Hedgehog Proteins/*genetics
Kruppel-Like Transcription Factors/*genetics
Nuclear Proteins/*genetics
SOXF Transcription Factors/*genetics
Transcription Factors/*genetics
Binding Sites ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Diffusion Chambers, Culture ; Female ; HeLa Cells ; Hedgehog Proteins/metabolism ; Humans ; Kruppel-Like Transcription Factors/metabolism ; Nuclear Proteins/metabolism ; Promoter Regions, Genetic ; Protein Binding ; SOXF Transcription Factors/metabolism ; Transcription Factors/metabolism ; Zinc Finger Protein GLI1 ; Zinc Finger Protein Gli2

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 41.

Tytuł:

Girdin regulates the migration and invasion of glioma cells via the PI3K-Akt signaling pathway.

Autorzy:

Ni W; Department of Human Anatomy, Histology and Embryology, China Medical University, Shenyang, Liaoning 110001, P.R. China.
Fang Y; Department of Human Anatomy, Histology and Embryology, Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Tong L; Department of Human Anatomy, Histology and Embryology, China Medical University, Shenyang, Liaoning 110001, P.R. China.
Tong Z; Department of Human Anatomy, Histology and Embryology, China Medical University, Shenyang, Liaoning 110001, P.R. China.
Yi F; Department of Neurosurgery, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Qiu J; Department of Neurosurgery, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Wang R; Department of Neurosurgery, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Tong X; Department of Human Anatomy, Histology and Embryology, China Medical University, Shenyang, Liaoning 110001, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2015 Oct; Vol. 12 (4), pp. 5086-92. Date of Electronic Publication: 2015 Jul 07.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Microfilament Proteins/*antagonists & inhibitors
Neuroglia/*metabolism
Phosphatidylinositol 3-Kinases/*genetics
Proto-Oncogene Proteins c-akt/*genetics
RNA, Small Interfering/*genetics
Vesicular Transport Proteins/*antagonists & inhibitors
Apoptosis ; Biological Assay ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Diffusion Chambers, Culture ; Gene Silencing ; Humans ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Neuroglia/pathology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering/metabolism ; Signal Transduction ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 42.

Tytuł:

MicroRNA‑205 promotes the tumorigenesis of nasopharyngeal carcinoma through targeting tumor protein p53-inducible nuclear protein 1.

Autorzy:

Nie G; Department of Otolaryngology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Duan H; Department of Otolaryngology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Li X; Department of Clinical Laboratory, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Yu Z; Central Laboratory, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Luo L; Department of Otolaryngology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Lu R; Department of Clinical Laboratory, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Ji Z; Department of Clinical Medicine, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Zhang W; Shenzhen Key Laboratory for Translational Medicine of Dermatology, Biomedical Research Institute, Shenzhen Peking University ‑ The Hong Kong University of Science and Technology Medical Center, Shenzhen, Guangdong 518036, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2015 Oct; Vol. 12 (4), pp. 5715-22. Date of Electronic Publication: 2015 Aug 05.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Carcinogenesis/*genetics
Carrier Proteins/*genetics
Heat-Shock Proteins/*genetics
MicroRNAs/*genetics
Nasopharyngeal Neoplasms/*genetics
Adult ; Apoptosis ; Base Sequence ; Carcinogenesis/metabolism ; Carcinogenesis/pathology ; Carcinoma ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Collagen/chemistry ; Diffusion Chambers, Culture ; Drug Combinations ; Female ; Genes, Reporter ; Heat-Shock Proteins/metabolism ; Humans ; Laminin/chemistry ; Luciferases/genetics ; Luciferases/metabolism ; Male ; MicroRNAs/metabolism ; Middle Aged ; Molecular Sequence Data ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms/metabolism ; Nasopharyngeal Neoplasms/pathology ; Nasopharynx/metabolism ; Nasopharynx/pathology ; Neoplasm Staging ; Proteoglycans/chemistry ; Signal Transduction

Czasopismo naukowe

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Skocz do pozycji: 43.

Tytuł:

Effects of Ras homolog gene family, member C gene silencing combined with rapamycin on hepatocellular carcinoma cell growth.

Autorzy:

Xie SL; Department of General Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Zhu MG; Department of Immunology, Basic Medical College of Jilin University, Changchun, Jilin 130021, P.R. China.
Chen GF; Department of General Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Wang GY; Department of General Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Lv GY; Department of General Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2015 Oct; Vol. 12 (4), pp. 5077-85. Date of Electronic Publication: 2015 Jul 08.

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Antineoplastic Agents/*pharmacology
RNA, Small Interfering/*genetics
Sirolimus/*pharmacology
TOR Serine-Threonine Kinases/*antagonists & inhibitors
rho GTP-Binding Proteins/*antagonists & inhibitors
Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclin-Dependent Kinase 2/genetics ; Cyclin-Dependent Kinase 2/metabolism ; Cyclin-Dependent Kinase Inhibitor p16 ; Diffusion Chambers, Culture ; Gene Silencing ; Hepatocytes/cytology ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Small Interfering/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; rho GTP-Binding Proteins/genetics ; rho GTP-Binding Proteins/metabolism ; rhoC GTP-Binding Protein

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Skocz do pozycji: 44.

Tytuł:

Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy.

Autorzy:

Cheng W; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Ainiwaer A; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Xiao L; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Cao Q; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Wu G; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Yang Y; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Mao R; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.
Bao Y; Department of Oncology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2015 Aug; Vol. 12 (2), pp. 2451-6. Date of Electronic Publication: 2015 May 04.

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
HSP90 Heat-Shock Proteins/*antagonists & inhibitors
Isoxazoles/*pharmacology
Neovascularization, Pathologic/*prevention & control
Resorcinols/*pharmacology
Adult ; Aged ; Carcinoma, Hepatocellular/blood supply ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Case-Control Studies ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Diffusion Chambers, Culture ; Dose-Response Relationship, Drug ; Female ; HEK293 Cells ; HSP90 Heat-Shock Proteins/genetics ; HSP90 Heat-Shock Proteins/metabolism ; Hep G2 Cells ; Humans ; Liver Neoplasms/blood supply ; Liver Neoplasms/drug therapy ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Signal Transduction

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Skocz do pozycji: 45.

Tytuł:

Response of a clinical Escherichia coli strain to repeated cefquinome exposure in a piglet tissue-cage model.

Autorzy:

Gu M; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Zhang N; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Zhang L; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Xiong M; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Yang Y; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Gu X; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Shen X; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .
Ding H; National Reference Laboratory of Veterinary Drug Residues (SCAU), College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. .

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Źródło:

BMC veterinary research [BMC Vet Res] 2015 Jul 25; Vol. 11, pp. 169. Date of Electronic Publication: 2015 Jul 25.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Cephalosporins/*therapeutic use
Escherichia coli Infections/*drug therapy
Swine Diseases/*microbiology
Animals ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/therapeutic use ; Cephalosporins/administration & dosage ; Diffusion Chambers, Culture/veterinary ; Dose-Response Relationship, Drug ; Male ; Microbial Sensitivity Tests ; Random Allocation ; Swine

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Skocz do pozycji: 46.

Tytuł:

Estrogen receptorβ2 regulates interlukin-12 receptorβ2 expression via p38 mitogen-activated protein kinase signaling and inhibits non-small-cell lung cancer proliferation and invasion.

Autorzy:

Liu ZG; Department of General Thoracic Surgery, First Affiliated Hospital, Sun‑Yat sen University, Guangzhou, Guangdong 510089, P.R. China.
Jiao XY; Organ Transplantation Center, First Affiliated Hospital, Sun Yat‑Sen University, Guangzhou, Guangdong 510080, P.R. China.
Chen ZG; Department of General Thoracic Surgery, First Affiliated Hospital, Sun‑Yat sen University, Guangzhou, Guangdong 510089, P.R. China.
Feng K; Department of General Thoracic Surgery, First Affiliated Hospital, Sun‑Yat sen University, Guangzhou, Guangdong 510089, P.R. China.
Luo HH; Department of General Thoracic Surgery, First Affiliated Hospital, Sun‑Yat sen University, Guangzhou, Guangdong 510089, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2015 Jul; Vol. 12 (1), pp. 248-54. Date of Electronic Publication: 2015 Feb 17.

Typ publikacji:

Journal Article

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Epithelial Cells/*metabolism
Estrogen Receptor beta/*genetics
Receptors, Interleukin-12/*genetics
p38 Mitogen-Activated Protein Kinases/*genetics
Bronchi/metabolism ; Bronchi/pathology ; Cell Line, Tumor ; Cell Movement ; Cell Nucleus/metabolism ; Cell Proliferation ; Cytoplasm/metabolism ; Diffusion Chambers, Culture ; Epithelial Cells/pathology ; Estrogen Receptor beta/metabolism ; Humans ; Protein Binding ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Receptors, Interleukin-12/antagonists & inhibitors ; Receptors, Interleukin-12/metabolism ; Signal Transduction ; p38 Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 47.

Tytuł:

Knockdown of ubiquitin protein ligase E3A affects proliferation and invasion, and induces apoptosis of breast cancer cells through regulation of annexin A2.

Autorzy:

Zhou X; Department of Anatomy, North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Deng S; Department of Anatomy, North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Liu H; Department of Otolaryngology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Liu Y; Department of Otolaryngology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Yang Z; Morphometric Research Laboratory, North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Xing T; Department of General Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Jing B; Institute of Immunology and Molecular Biology, North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.
Zhang X; Sichuan Key Laboratory of Medical Imaging, North Sichuan Medical College, Nanchong, Sichuan 637007, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2015 Jul; Vol. 12 (1), pp. 1107-13. Date of Electronic Publication: 2015 Mar 26.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Annexin A2/*genetics
Mammary Glands, Human/*metabolism
Ubiquitin-Protein Ligases/*genetics
Annexin A2/metabolism ; Cell Cycle ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Diffusion Chambers, Culture ; Female ; Humans ; Mammary Glands, Human/pathology ; RNA Interference ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Ubiquitin-Protein Ligases/antagonists & inhibitors ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 48.

Tytuł:

MiR-506 suppresses tumor proliferation and invasion by targeting FOXQ1 in nasopharyngeal carcinoma.

Autorzy:

Zhang Z; Department of Human Anatomy, Hebei Medical University, Shijiazhuang, PR China.
Ma J; Department of Human Anatomy, Hebei Medical University, Shijiazhuang, PR China.
Luan G; The Third Hospital of Hebei Medical University, Shijiazhuang, PR China.
Kang L; Department of Human Anatomy, Hebei Medical University, Shijiazhuang, PR China.
Su Y; Department of Human Anatomy, Hebei Medical University, Shijiazhuang, PR China.
He Y; Department of Otorhinolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, PR China.
Luan F; Department of Otorhinolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, PR China.

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Źródło:

PloS one [PLoS One] 2015 Apr 09; Vol. 10 (4), pp. e0122851. Date of Electronic Publication: 2015 Apr 09 (Print Publication: 2015).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication

MeSH Terms:

Gene Expression Regulation, Neoplastic*
Forkhead Transcription Factors/*genetics
MicroRNAs/*genetics
Nasopharyngeal Neoplasms/*genetics
Base Sequence ; Carcinoma ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Diffusion Chambers, Culture ; Forkhead Transcription Factors/metabolism ; Genes, Reporter ; Humans ; Luciferases/genetics ; Luciferases/metabolism ; MicroRNAs/metabolism ; Molecular Sequence Data ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms/metabolism ; Nasopharyngeal Neoplasms/pathology ; Signal Transduction

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Skocz do pozycji: 49.

Tytuł:

Development of ciclopirox olamine topical formulations: evaluation of drug release, penetration and cutaneous retention.

Autorzy:

Pinheiro VA; Faculdade de Ciências Farmacêuticas da, Universidade de São Paulo , São Paulo, SP , Brazil.
Serikaku D
Baby AR
Velasco MV
Kaneko TM
Consiglieri VO

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Źródło:

Pharmaceutical development and technology [Pharm Dev Technol] 2015 Mar; Vol. 20 (2), pp. 197-203. Date of Electronic Publication: 2013 Nov 29.

Typ publikacji:

Journal Article

MeSH Terms:

Drug Design*
Skin Absorption*
Antifungal Agents/*administration & dosage
Antifungal Agents/*chemistry
Pyridones/*administration & dosage
Pyridones/*chemistry
Skin/*metabolism
Administration, Cutaneous ; Animals ; Antifungal Agents/pharmacokinetics ; Chemistry, Pharmaceutical ; Ciclopirox ; Diffusion Chambers, Culture ; Drug Liberation ; Drug Stability ; In Vitro Techniques ; Permeability ; Pyridones/pharmacokinetics ; Skin/drug effects ; Skin Cream ; Swine

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Skocz do pozycji: 50.

Tytuł:

Diffusion chamber system for testing of collagen-based cell migration barriers for separation of ligament enthesis zones in tissue-engineered ACL constructs.

Autorzy:

Hahner J; a Leibniz-Institut für Polymerforschung, Institute of Polymer Materials , Hohe Straße 6, 01069 Dresden , Germany.
Hoyer M; b Central Laboratory , DRK Manniske-Hospital , An der Wipper 2, 06567 Bad Frankenhausen , Germany.; c Department of Bioanalytics , Technical University , Seestraße 13, 13353 Berlin , Germany.
Hillig S; a Leibniz-Institut für Polymerforschung, Institute of Polymer Materials , Hohe Straße 6, 01069 Dresden , Germany.
Schulze-Tanzil G; d Institute of Anatomy , Paracelsus Medical University , Salzburg and Nuremberg, Prof. Ernst Nathan Straße 1, 90340 Nuremberg , Germany.; e Department of Trauma and Reconstructive Surgery , Charité-Universitätsmedizin Berlin , Campus Benjamin Franklin, Garystrasse 5, 14195 Berlin , Germany.
Meyer M; f Research Institute of Leather and Plastic Sheeting - FILK , Meißner Ring 1-5, 09599 Freiberg , Germany.
Schröpfer M; f Research Institute of Leather and Plastic Sheeting - FILK , Meißner Ring 1-5, 09599 Freiberg , Germany.
Lohan A; g Forschungseinrichtungen für Experimentelle Medizin, Charité-Universitätsmedizin Berlin , Campus Benjamin Franklin, Kramerstr.6-10, 12207 Berlin , Germany.
Garbe LA; c Department of Bioanalytics , Technical University , Seestraße 13, 13353 Berlin , Germany.
Heinrich G; a Leibniz-Institut für Polymerforschung, Institute of Polymer Materials , Hohe Straße 6, 01069 Dresden , Germany.; h Institute of Materials Science , Technische Universität Dresden , Helmholtzstraße 10, 01062 Dresden , Germany.
Breier A; a Leibniz-Institut für Polymerforschung, Institute of Polymer Materials , Hohe Straße 6, 01069 Dresden , Germany.

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Źródło:

Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2015; Vol. 26 (16), pp. 1085-99. Date of Electronic Publication: 2015 Aug 24.

Typ publikacji:

Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Tissue Engineering*
Anterior Cruciate Ligament/*cytology
Anterior Cruciate Ligament Reconstruction/*methods
Collagen/*chemistry
Connective Tissue Cells/*cytology
Materials Testing/*methods
Tissue Scaffolds/*chemistry
Animals ; Anterior Cruciate Ligament/metabolism ; Anterior Cruciate Ligament/surgery ; Cattle ; Cell Adhesion ; Cell Migration Assays/methods ; Cell Movement ; Cell Survival ; Cells, Cultured ; Connective Tissue Cells/metabolism ; Diffusion Chambers, Culture ; Female ; Humans ; Materials Testing/instrumentation ; Microscopy, Electron, Scanning ; Polyesters/chemistry ; Polypropylenes/chemistry ; Rabbits ; Surface Properties

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