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Wyszukujesz frazę ""Dihydro-beta-Erythroidine"" wg kryterium: Temat


Tytuł :
The Place of Erythroidines in the History of Neuromuscular Blockers.
Autorzy :
McKenzie AG; Department of Anaesthesia, Critical Care & Pain Medicine, Royal Infirmary of Edinburgh, UK. Electronic address: .
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Źródło :
Journal of anesthesia history [J Anesth Hist] 2019 Jan; Vol. 5 (1), pp. 22-24. Date of Electronic Publication: 2018 Nov 06.
Typ publikacji :
Historical Article; Journal Article
MeSH Terms :
Anesthesia/*history
Curare/*history
Dihydro-beta-Erythroidine/*history
Neuromuscular Blocking Agents/*history
Anesthesia/methods ; Dihydro-beta-Erythroidine/chemistry ; Dihydro-beta-Erythroidine/pharmacology ; History, 20th Century ; Humans ; Muscle Relaxation/drug effects ; Neuromuscular Blocking Agents/chemistry ; Neuromuscular Blocking Agents/pharmacology
Czasopismo naukowe
Tytuł :
Nicotine Induced Neurocognitive Protection and Anti-inflammation Effect by Activating α 4β 2 Nicotinic Acetylcholine Receptors in Ischemic Rats.
Autorzy :
Han T; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.
Wang Q; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.
Lai R; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.; Department of Nuclear Medicine, Nanjing Drum Tower Hospital, Nanjing, China.
Zhang D; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.
Diao Y; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.
Yin Y; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.; Department of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło :
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco [Nicotine Tob Res] 2020 May 26; Vol. 22 (6), pp. 919-924.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*prevention & control
Ischemia/*complications
Neurocognitive Disorders/*prevention & control
Nicotine/*administration & dosage
Nicotinic Agonists/*pharmacology
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*metabolism
Animals ; Dihydro-beta-Erythroidine/pharmacology ; Inflammation/etiology ; Inflammation/metabolism ; Inflammation/pathology ; Ischemia/pathology ; Male ; Neurocognitive Disorders/etiology ; Neurocognitive Disorders/metabolism ; Neurocognitive Disorders/pathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
HPLC-DAD-SPE-NMR isolation of tetracyclic spiro-alkaloids with antiplasmodial activity from the seeds of Erythrina latissima .
Autorzy :
Zarev Y; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, Sofia, Bulgaria.
Foubert K; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Cos P; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Elgorashi E; Toxicology and Ethnoveterinary Medicine; Food, Feed and Veterinary Public Health, ARC-Onderstepoort Veterinary Institute, Onderstepoort, South-Africa.
Apers S; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Ionkova I; Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, Sofia, Bulgaria.
Pieters L; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
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Źródło :
Natural product research [Nat Prod Res] 2020 Apr; Vol. 34 (7), pp. 1037-1040. Date of Electronic Publication: 2019 Jan 03.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*isolation & purification
Alkaloids/*pharmacology
Antimalarials/*isolation & purification
Erythrina/*chemistry
Plant Extracts/*chemistry
Alkaloids/chemistry ; Antimalarials/chemistry ; Cell Line ; Chloroquine/pharmacology ; Chromatography, High Pressure Liquid ; Dihydro-beta-Erythroidine/analogs & derivatives ; Drug Resistance ; Humans ; Indole Alkaloids ; Magnetic Resonance Spectroscopy ; Plant Extracts/analysis ; Plant Extracts/pharmacology ; Plasmodium falciparum/drug effects ; Seeds/chemistry
Czasopismo naukowe
Tytuł :
Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors, decreases ethanol consumption in alcohol-preferring UChB rats.
Autorzy :
Quiroz G; Programa de Doctorado en Farmacología, Universidad de Chile, Santiago, Chile.
Guerra-Díaz N; Programa de Doctorado en Química, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.
Iturriaga-Vásquez P; Laboratorio de Farmacoquímica, Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería y Ciencias, Universidad de la Frontera, Temuco, Chile.
Rivera-Meza M; Departamento de Química Farmacológica y Toxicológica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.
Quintanilla ME; Programa de Farmacología Molecular y Clínica, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile. Electronic address: .
Sotomayor-Zárate R; Laboratorio de Neuroquímica y Neurofarmacología, CENFI, Instituto de Fisiología, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile. Electronic address: .
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Źródło :
Behavioural brain research [Behav Brain Res] 2018 Sep 03; Vol. 349, pp. 169-176. Date of Electronic Publication: 2018 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alcohol Deterrents/*pharmacology
Alcohol Drinking/*drug therapy
Dihydro-beta-Erythroidine/*analogs & derivatives
Nicotinic Antagonists/*pharmacology
Alcohol Drinking/metabolism ; Animals ; Central Nervous System Depressants/administration & dosage ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Ethanol/administration & dosage ; Male ; Motor Activity/drug effects ; Motor Activity/physiology ; Random Allocation ; Rats, Sprague-Dawley ; Rats, Wistar ; Receptors, Nicotinic/metabolism ; Reward
Czasopismo naukowe
Tytuł :
Brainstem cholinergic pathways diminish cardiovascular and neuroinflammatory actions of endotoxemia in rats: Role of NFκB/α7/α4β2AChRs signaling.
Autorzy :
Sallam MY; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Egypt.
El-Gowilly SM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Egypt.
Fouda MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Egypt.
Abd-Alhaseeb MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhour University, Egypt.
El-Mas MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Egypt. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2019 Oct; Vol. 157, pp. 107683. Date of Electronic Publication: 2019 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholinergic Fibers/*physiology
Endotoxemia/*prevention & control
Hypotension/*prevention & control
NF-kappa B/*biosynthesis
Neurogenic Inflammation/*prevention & control
Receptors, Nicotinic/*biosynthesis
alpha7 Nicotinic Acetylcholine Receptor/*biosynthesis
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Animals ; Azetidines/pharmacology ; Bradycardia/complications ; Bradycardia/prevention & control ; Bridged Bicyclo Compounds, Heterocyclic/administration & dosage ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Endotoxemia/complications ; Hypotension/chemically induced ; Hypotension/complications ; Infusions, Intraventricular ; Lipopolysaccharides ; Male ; Medulla Oblongata/metabolism ; Neural Pathways/physiology ; Nicotine/pharmacology ; Pyridines/pharmacology ; Quinuclidines/administration & dosage ; Quinuclidines/pharmacology ; Rats ; Signal Transduction ; Solitary Nucleus/metabolism ; Tachycardia/chemically induced ; Tachycardia/prevention & control
Czasopismo naukowe
Tytuł :
Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine.
Autorzy :
Clementson S; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Universitetsparken 2 , 2100 Copenhagen , Denmark.; Molecular Discovery and Innovation , H. Lundbeck A/S , Ottiliavej 9 , 2500 Valby , Denmark.
Jessing M; Molecular Discovery and Innovation , H. Lundbeck A/S , Ottiliavej 9 , 2500 Valby , Denmark.
Pedersen H; Compound Management and Analytical Chemistry , H. Lundbeck A/S , Ottiliavej 9 , 2500 Valby , Denmark.
Vital P; Molecular Discovery and Innovation , H. Lundbeck A/S , Ottiliavej 9 , 2500 Valby , Denmark.
Kristensen JL; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Universitetsparken 2 , 2100 Copenhagen , Denmark.
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Źródło :
Journal of the American Chemical Society [J Am Chem Soc] 2019 Jun 05; Vol. 141 (22), pp. 8783-8786. Date of Electronic Publication: 2019 May 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dihydro-beta-Erythroidine/*chemical synthesis
Dihydro-beta-Erythroidine/*chemistry
Chemistry Techniques, Synthetic ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor.
Autorzy :
Yu R; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Tae HS; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, NSW, Australia.
Xu Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Craik DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Adams DJ; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, NSW, Australia.
Jiang T; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Kaas Q; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2019 Aug; Vol. 176 (15), pp. 2750-2763. Date of Electronic Publication: 2019 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dihydro-beta-Erythroidine/*pharmacology
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*metabolism
Animals ; Molecular Dynamics Simulation ; Oocytes ; Protein Structural Elements/drug effects ; Receptors, Nicotinic/chemistry ; Receptors, Nicotinic/physiology ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Nicotine enhances responding for conditioned reinforcement via α4β2 nicotinic acetylcholine receptors in the ventral tegmental area, but not the nucleus accumbens or the prefrontal cortex.
Autorzy :
Tabbara RI; Section of Biopsychology and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., M5T 1R8, Toronto, ON, Canada; Department of Psychology, University of Toronto, 100 St. George St., M5S 3G3, Toronto, ON, Canada. Electronic address: .
Fletcher PJ; Section of Biopsychology and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., M5T 1R8, Toronto, ON, Canada; Department of Psychology, University of Toronto, 100 St. George St., M5S 3G3, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, 250 College St., M5T 1R8, Toronto, ON, Canada.
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Źródło :
Neuropharmacology [Neuropharmacology] 2019 Apr; Vol. 148, pp. 68-76. Date of Electronic Publication: 2018 Dec 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Conditioning, Operant/*physiology
Nicotine/*pharmacology
Nucleus Accumbens/*physiology
Prefrontal Cortex/*physiology
Receptors, Nicotinic/*physiology
Ventral Tegmental Area/*physiology
Animals ; Conditioning, Classical/drug effects ; Conditioning, Operant/drug effects ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Male ; Nicotinic Agonists/pharmacology ; Nicotinic Antagonists/pharmacology ; Nucleus Accumbens/drug effects ; Prefrontal Cortex/drug effects ; Rats ; Reinforcement, Psychology ; Self Administration ; Ventral Tegmental Area/drug effects
Czasopismo naukowe
Tytuł :
Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test.
Autorzy :
Bagdas D; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA.
AlSharari S; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA; Department of Pharmacology and Toxicology, King Saud University, Riyadh, Saudi Arabia.
Roni MA; Department of Pharmaceutical Sciences, Hampton University School of Pharmacy, Hampton, VA, 23668, USA.
Campbell VC; Department of Pharmaceutical Sciences, Hampton University School of Pharmacy, Hampton, VA, 23668, USA.
Muldoon PP; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA.
Carroll FI; Center for Organic and Medicinal Chemistry, Research Triangle Institute, Research Triangle Park, NC 27709, USA.
Damaj MI; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA. Electronic address: .
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Źródło :
Behavioural brain research [Behav Brain Res] 2019 Mar 15; Vol. 360, pp. 262-269. Date of Electronic Publication: 2018 Dec 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antidepressive Agents, Second-Generation/*pharmacology
Bupropion/*pharmacology
Receptors, Nicotinic/*metabolism
Swimming/*psychology
Analysis of Variance ; Animals ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Immobility Response, Tonic/physiology ; Locomotion/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Mutation/genetics ; Protein Subunits/genetics ; Protein Subunits/metabolism ; Psychomotor Performance/drug effects ; Receptors, Nicotinic/genetics
Czasopismo naukowe
Tytuł :
Inhibition of Nigrostriatal Dopamine Release by Striatal GABA A and GABA B Receptors.
Autorzy :
Lopes EF; Centre for Integrative Neuroscience, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, and.
Roberts BM; Centre for Integrative Neuroscience, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, and.
Siddorn RE; Centre for Integrative Neuroscience, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, and.
Clements MA; Centre for Integrative Neuroscience, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, and.
Cragg SJ; Centre for Integrative Neuroscience, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, and .; Oxford Parkinson's Disease Centre, Oxford OX1 3PT, United Kingdom.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2019 Feb 06; Vol. 39 (6), pp. 1058-1065. Date of Electronic Publication: 2018 Dec 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Corpus Striatum/*metabolism
Dopamine/*metabolism
Receptors, GABA-A/*metabolism
Receptors, GABA-B/*metabolism
Substantia Nigra/*metabolism
Animals ; Axons/metabolism ; Cholinergic Antagonists/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Electric Stimulation ; GABA Agonists/pharmacology ; GABA Antagonists/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Optogenetics ; Parasympathetic Nervous System/drug effects ; Parasympathetic Nervous System/metabolism ; Receptors, GABA-A/drug effects ; Receptors, GABA-B/drug effects ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł :
Modulation of aggressive behavior in mice by nicotinic receptor subtypes.
Autorzy :
Lewis AS; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States. Electronic address: .
Mineur YS; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States. Electronic address: .
Smith PH; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States. Electronic address: .
Cahuzac ELM; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States. Electronic address: .
Picciotto MR; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2015 Oct 15; Vol. 97 (4), pp. 488-497. Date of Electronic Publication: 2015 Jul 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Aconitine/*analogs & derivatives
Aggression/*drug effects
Behavior, Animal/*drug effects
Dihydro-beta-Erythroidine/*pharmacology
Nicotine/*pharmacology
Receptors, Nicotinic/*metabolism
Aconitine/administration & dosage ; Aconitine/pharmacology ; Animals ; Dihydro-beta-Erythroidine/administration & dosage ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Nicotine/administration & dosage ; Nicotinic Agonists/administration & dosage ; Nicotinic Agonists/pharmacology ; Nicotinic Antagonists/administration & dosage ; Nicotinic Antagonists/pharmacology
Czasopismo naukowe
Tytuł :
A behavioral economic analysis of the value-enhancing effects of nicotine and varenicline and the role of nicotinic acetylcholine receptors in male and female rats.
Autorzy :
Barrett ST; Department of Psychology, University of Nebraska, Lincoln, Nebraska, USA.
Geary TN
Steiner AN
Bevins RA
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Źródło :
Behavioural pharmacology [Behav Pharmacol] 2018 Sep; Vol. 29 (6), pp. 493-502.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Sex Characteristics*
Conditioning, Operant/*drug effects
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
Receptors, Nicotinic/*metabolism
Varenicline/*pharmacology
Animals ; Cues ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Economics, Behavioral ; Female ; Locomotion/drug effects ; Male ; Photic Stimulation ; Rats ; Rats, Sprague-Dawley ; Reinforcement, Psychology
Czasopismo naukowe
Tytuł :
Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury.
Autorzy :
Kiguchi N; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan. .
Kobayashi D; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
Saika F; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
Matsuzaki S; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
Kishioka S; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
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Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2018 Mar 27; Vol. 15 (1), pp. 96. Date of Electronic Publication: 2018 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Macrophages/*drug effects
Microglia/*drug effects
Nicotinic Agonists/*therapeutic use
Sciatic Neuropathy/*drug therapy
Sciatic Neuropathy/*pathology
Spinal Cord/*pathology
Animals ; Cytokines/genetics ; Cytokines/metabolism ; Dihydro-beta-Erythroidine/therapeutic use ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Functional Laterality/drug effects ; Gene Expression Regulation/drug effects ; Hyperalgesia/drug therapy ; Macrophage Activation ; Male ; Mice ; Mice, Inbred ICR ; Nicotinic Agonists/pharmacology ; Pain Threshold/drug effects ; Pyridines/pharmacology ; Pyridines/therapeutic use ; RNA, Messenger/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Nicotinic activity depresses synaptic potentiation in layer V pyramidal neurons of mouse insular cortex.
Autorzy :
Sato H; Department of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan.
Kawano T; Department of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan.
Yin DX; Department of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan.
Kato T; Department of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan.
Toyoda H; Department of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2017 Sep 01; Vol. 358, pp. 13-27. Date of Electronic Publication: 2017 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Cortex/*cytology
Cholinergic Agents/*pharmacology
Neural Inhibition/*drug effects
Nicotine/*pharmacology
Pyramidal Cells/*drug effects
Synaptic Potentials/*drug effects
Acetylcholine/pharmacology ; Animals ; Animals, Newborn ; Bicuculline/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; GABA-A Receptor Antagonists/pharmacology ; Lysine/analogs & derivatives ; Lysine/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Quinoxalines/pharmacology ; Valine/analogs & derivatives ; Valine/pharmacology
Czasopismo naukowe
Tytuł :
Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHβE suggests a unique mode of antagonism.
Autorzy :
Shahsavar A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kastrup JS
Nielsen EØ
Kristensen JL
Gajhede M
Balle T
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Źródło :
PloS one [PLoS One] 2012; Vol. 7 (8), pp. e40757. Date of Electronic Publication: 2012 Aug 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymnaea*
Dihydro-beta-Erythroidine/*chemistry
Dihydro-beta-Erythroidine/*pharmacology
Nicotinic Antagonists/*chemistry
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*chemistry
Receptors, Nicotinic/*metabolism
Animals ; Crystallography, X-Ray ; Dihydro-beta-Erythroidine/metabolism ; Hydrogen Bonding ; Models, Molecular ; Nicotinic Agonists/chemistry ; Nicotinic Agonists/metabolism ; Nicotinic Antagonists/metabolism ; Protein Conformation
Czasopismo naukowe
Tytuł :
The discriminative stimulus effects of i.v. nicotine in rhesus monkeys: Pharmacokinetics and apparent pA 2 analysis with dihydro-β-erythroidine.
Autorzy :
Moerke MJ; Department of Pharmacology, The University of Texas Health Science Center, San Antonio, TX, USA.
Zhu AZ; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Department of Pharmacology and Toxicology, and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Tyndale RF; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Department of Pharmacology and Toxicology, and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Javors MA; Department of Psychiatry, The University of Texas Health Science Center, San Antonio, TX, USA.
McMahon LR; Department of Pharmacology, The University of Texas Health Science Center, San Antonio, TX, USA. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2017 Apr; Vol. 116, pp. 9-17. Date of Electronic Publication: 2016 Dec 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Discrimination Learning/*drug effects
Nicotine/*administration & dosage
Nicotine/*pharmacokinetics
Nicotinic Agonists/*administration & dosage
Nicotinic Agonists/*pharmacokinetics
Administration, Intravenous ; Animals ; Conditioning, Operant/drug effects ; Cotinine/analogs & derivatives ; Cotinine/blood ; Cotinine/pharmacokinetics ; Dihydro-beta-Erythroidine/administration & dosage ; Dihydro-beta-Erythroidine/blood ; Dihydro-beta-Erythroidine/pharmacokinetics ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Electroshock ; Female ; Macaca mulatta ; Male ; Nicotine/blood ; Nicotinic Agonists/blood ; Smoking/blood ; Varenicline/administration & dosage ; Varenicline/blood ; Varenicline/pharmacokinetics
Czasopismo naukowe
Tytuł :
Impact of ageing on postsynaptic neuronal nicotinic neurotransmission in auditory thalamus.
Autorzy :
Sottile SY; Department of Pharmacology.
Ling L; Department of Pharmacology.
Cox BC; Department of Pharmacology.; Department of Surgery, Division of Otolaryngology, Southern Illinois University School of Medicine, Springfield, IL, USA.
Caspary DM; Department of Pharmacology.; Department of Surgery, Division of Otolaryngology, Southern Illinois University School of Medicine, Springfield, IL, USA.
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Źródło :
The Journal of physiology [J Physiol] 2017 Aug 01; Vol. 595 (15), pp. 5375-5385. Date of Electronic Publication: 2017 Jul 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging/*physiology
Geniculate Bodies/*physiology
Receptors, Nicotinic/*physiology
Synaptic Potentials/*physiology
Acetylcholine/pharmacology ; Animals ; Cholinergic Agonists/pharmacology ; Cholinergic Antagonists/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Neurons/physiology ; Rats
Czasopismo naukowe
Tytuł :
Varenicline provokes impulsive action by stimulating α4β2 nicotinic acetylcholine receptors in the infralimbic cortex in a nicotine exposure status-dependent manner.
Autorzy :
Ohmura Y; Department of Neuropharmacology, Hokkaido University, Graduate School of Medicine, Japan. Electronic address: .
Sasamori H; Hokkaido University, School of Medicine, Japan.
Tsutsui-Kimura I; Department of Neuropharmacology, Hokkaido University, Graduate School of Medicine, Japan; Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; Research Fellow of Japan Society for the Promotion of Science, Japan.
Izumi T; Department of Neuropharmacology, Hokkaido University, Graduate School of Medicine, Japan.
Yoshida T; Department of Neuropharmacology, Hokkaido University, Graduate School of Medicine, Japan.
Yoshioka M; Department of Neuropharmacology, Hokkaido University, Graduate School of Medicine, Japan.
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Źródło :
Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2017 Mar; Vol. 154, pp. 1-10. Date of Electronic Publication: 2017 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Impulsive Behavior/*drug effects
Limbic Lobe/*drug effects
Nicotine/*pharmacology
Receptors, Nicotinic/*drug effects
Varenicline/*pharmacology
Administration, Oral ; Animals ; Appetite/drug effects ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Drug Interactions ; Hypodermoclysis ; Male ; Microinjections ; Nicotinic Agonists/pharmacology ; Rats ; Varenicline/administration & dosage ; Varenicline/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Autorzy :
de Moura FB; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3900, USA.
McMahon LR; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3900, USA. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2017 Mar; Vol. 234 (5), pp. 781-792. Date of Electronic Publication: 2016 Dec 27.
Typ publikacji :
Journal Article
MeSH Terms :
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*drug effects
Varenicline/*pharmacology
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Alkaloids/pharmacology ; Animals ; Azocines/pharmacology ; Benzamides/pharmacology ; Bridged Bicyclo Compounds/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Cocaine/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Discrimination, Psychological ; Dopamine Uptake Inhibitors/pharmacology ; Hypnotics and Sedatives/pharmacology ; Ibogaine/analogs & derivatives ; Ibogaine/pharmacology ; Male ; Mecamylamine/pharmacology ; Mice ; Mice, Inbred C57BL ; Midazolam/pharmacology ; Nerve Tissue Proteins/drug effects ; Pyridines/pharmacology ; Quinolizines/pharmacology ; alpha7 Nicotinic Acetylcholine Receptor/drug effects
Czasopismo naukowe
Tytuł :
N-Methyl-d-aspartate Modulation of Nucleus Accumbens Dopamine Release by Metabotropic Glutamate Receptors: Fast Cyclic Voltammetry Studies in Rat Brain Slices in Vitro.
Autorzy :
Yavas E; Department of Neuroscience, Psychology and Behaviour, University of Leicester , Lancaster Road, Leicester LE1 9HN, United Kingdom.
Young AM; Department of Neuroscience, Psychology and Behaviour, University of Leicester , Lancaster Road, Leicester LE1 9HN, United Kingdom.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2017 Feb 15; Vol. 8 (2), pp. 320-328. Date of Electronic Publication: 2017 Feb 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dopamine/*metabolism
Excitatory Amino Acid Agonists/*pharmacology
N-Methylaspartate/*pharmacology
Nucleus Accumbens/*drug effects
Nucleus Accumbens/*metabolism
Receptors, Metabotropic Glutamate/*metabolism
Animals ; Animals, Newborn ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Electric Stimulation ; Electrochemical Techniques ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; GABA Antagonists/pharmacology ; In Vitro Techniques ; Nicotinic Antagonists/pharmacology ; Phencyclidine/pharmacology ; Picrotoxin/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe

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