Temat: "Dihydro-beta-Erythroidine" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors.
Autorzy:: Kumar P; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
Scholze P; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria.
Fronius M; Department of Physiology and HeartOtago, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Krasteva-Christ G; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
Hollenhorst MI; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2020 Dec; Vol. 177 (24), pp. 5595-5608. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Nicotine*/pharmacology
Receptors, Nicotinic*
Acetylcholine ; Animals ; Dihydro-beta-Erythroidine ; Mecamylamine ; Mice ; Nicotinic Agonists ; Nicotinic Antagonists/pharmacology

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Skocz do pozycji: 2.

Tytuł:: Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro-β-erythroidine in nicotine-tolerant mice.
Autorzy:: de Moura FB; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Behavioral Biology Program, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Wilkerson JL; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, USA.
McMahon LR; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Pokaż więcej
Źródło:: Brain and behavior [Brain Behav] 2020 Apr; Vol. 10 (4), pp. e01581. Date of Electronic Publication: 2020 Feb 24.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Drug Tolerance*
Dihydro-beta-Erythroidine/*pharmacology
Mecamylamine/*pharmacology
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
Nicotinic Antagonists/*pharmacology
Animals ; Dose-Response Relationship, Drug ; Male ; Mice ; Mice, Inbred C57BL ; Smoking Cessation

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Skocz do pozycji: 3.

Tytuł:: Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor.
Autorzy:: Yu R; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Tae HS; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, NSW, Australia.
Xu Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Craik DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Adams DJ; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, NSW, Australia.
Jiang T; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Kaas Q; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2019 Aug; Vol. 176 (15), pp. 2750-2763. Date of Electronic Publication: 2019 Jun 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dihydro-beta-Erythroidine/*pharmacology
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*metabolism
Animals ; Molecular Dynamics Simulation ; Oocytes ; Protein Structural Elements/drug effects ; Receptors, Nicotinic/chemistry ; Receptors, Nicotinic/physiology ; Xenopus laevis

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Skocz do pozycji: 4.

Tytuł:: Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHβE suggests a unique mode of antagonism.
Autorzy:: Shahsavar A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kastrup JS
Nielsen EØ
Kristensen JL
Gajhede M
Balle T; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (8), pp. e40757. Date of Electronic Publication: 2012 Aug 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Lymnaea*
Dihydro-beta-Erythroidine/*chemistry
Dihydro-beta-Erythroidine/*pharmacology
Nicotinic Antagonists/*chemistry
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*chemistry
Receptors, Nicotinic/*metabolism
Animals ; Crystallography, X-Ray ; Dihydro-beta-Erythroidine/metabolism ; Hydrogen Bonding ; Models, Molecular ; Nicotinic Agonists/chemistry ; Nicotinic Agonists/metabolism ; Nicotinic Antagonists/metabolism ; Protein Conformation

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Skocz do pozycji: 5.

Tytuł:: Effects of the competitive nicotinic antagonist erysodine on behavior occasioned or maintained by nicotine: comparison with mecamylamine.
Autorzy:: Mansbach RS; Department of Neuroscience, Pfizer Central Research, Groton, CT 06340, USA. />Chambers LK
Rovetti CC; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2000 Feb; Vol. 148 (3), pp. 234-42.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Behavior, Animal/*drug effects
Dihydro-beta-Erythroidine/*analogs & derivatives
Discrimination Learning/*drug effects
Mecamylamine/*pharmacology
Nicotinic Antagonists/*pharmacology
Animals ; Dihydro-beta-Erythroidine/pharmacology ; Dose-Response Relationship, Drug ; Male ; Rats ; Rats, Sprague-Dawley ; Receptors, Nicotinic/drug effects ; Reinforcement, Psychology ; Self Administration

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Skocz do pozycji: 6.

Tytuł:: Differential effects of α4β2 nicotinic receptor antagonists and partial-agonists on contextual fear extinction in male C57BL/6 mice.
Autorzy:: Kutlu MG; The Department of Biobehavioral Health, Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA, 16801, USA. .
Tumolo JM; Department of Psychology, Temple University, Philadelphia, PA, USA.
Cann C; The Department of Biobehavioral Health, Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA, 16801, USA.
Gould TJ; The Department of Biobehavioral Health, Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA, 16801, USA.; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2018 Apr; Vol. 235 (4), pp. 1211-1219. Date of Electronic Publication: 2018 Jan 30.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Azetidines/*pharmacology
Dihydro-beta-Erythroidine/*pharmacology
Extinction, Psychological/*drug effects
Fear/*drug effects
Nicotinic Agonists/*pharmacology
Nicotinic Antagonists/*pharmacology
Pyridines/*pharmacology
Receptors, Nicotinic/*physiology
Varenicline/*pharmacology
Animals ; Anxiety/drug therapy ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred C57BL ; Receptors, Nicotinic/drug effects ; Stress Disorders, Post-Traumatic/drug therapy

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Skocz do pozycji: 7.

Tytuł:: Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury.
Autorzy:: Kiguchi N; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan. .
Kobayashi D; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
Saika F; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
Matsuzaki S; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
Kishioka S; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2018 Mar 27; Vol. 15 (1), pp. 96. Date of Electronic Publication: 2018 Mar 27.
Typ publikacji:: Journal Article
MeSH Terms:: Macrophages/*drug effects
Microglia/*drug effects
Nicotinic Agonists/*therapeutic use
Sciatic Neuropathy/*drug therapy
Sciatic Neuropathy/*pathology
Spinal Cord/*pathology
Animals ; Cytokines/genetics ; Cytokines/metabolism ; Dihydro-beta-Erythroidine/therapeutic use ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Functional Laterality/drug effects ; Gene Expression Regulation/drug effects ; Hyperalgesia/drug therapy ; Macrophage Activation ; Male ; Mice ; Mice, Inbred ICR ; Nicotinic Agonists/pharmacology ; Pain Threshold/drug effects ; Pyridines/pharmacology ; Pyridines/therapeutic use ; RNA, Messenger/metabolism ; Time Factors

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Skocz do pozycji: 8.

Tytuł:: The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Autorzy:: de Moura FB; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3900, USA.
McMahon LR; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3900, USA. .; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2017 Mar; Vol. 234 (5), pp. 781-792. Date of Electronic Publication: 2016 Dec 27.
Typ publikacji:: Journal Article
MeSH Terms:: Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*drug effects
Varenicline/*pharmacology
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Alkaloids/pharmacology ; Animals ; Azocines/pharmacology ; Benzamides/pharmacology ; Bridged Bicyclo Compounds/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Cocaine/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Discrimination, Psychological ; Dopamine Uptake Inhibitors/pharmacology ; Hypnotics and Sedatives/pharmacology ; Ibogaine/analogs & derivatives ; Ibogaine/pharmacology ; Male ; Mecamylamine/pharmacology ; Mice ; Mice, Inbred C57BL ; Midazolam/pharmacology ; Nerve Tissue Proteins/drug effects ; Pyridines/pharmacology ; Quinolizines/pharmacology ; alpha7 Nicotinic Acetylcholine Receptor/drug effects

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Skocz do pozycji: 9.

Tytuł:: Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells.
Autorzy:: Qian J; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
Mummalaneni SK; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
Alkahtani RM; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
Mahavadi S; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
Murthy KS; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
Grider JR; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
Lyall V; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Nov 15; Vol. 11 (11), pp. e0166565. Date of Electronic Publication: 2016 Nov 15 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: Brain-Derived Neurotrophic Factor/*genetics
Nicotine/*metabolism
Receptors, G-Protein-Coupled/*biosynthesis
Receptors, Nicotinic/*biosynthesis
Animals ; Brain-Derived Neurotrophic Factor/antagonists & inhibitors ; Brain-Derived Neurotrophic Factor/biosynthesis ; Calcium/metabolism ; Cell Line ; Dihydro-beta-Erythroidine/administration & dosage ; Enterochromaffin Cells/metabolism ; Enteroendocrine Cells/metabolism ; Gene Expression Regulation/drug effects ; Intestinal Mucosa/cytology ; Intestinal Mucosa/metabolism ; Mecamylamine/administration & dosage ; Mecamylamine/metabolism ; Mice ; Nicotine/administration & dosage ; Nicotine/antagonists & inhibitors ; RNA, Messenger/biosynthesis ; Receptors, G-Protein-Coupled/genetics ; Receptors, Nicotinic/genetics

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Skocz do pozycji: 10.

Tytuł:: The insecticidal activity and action mode of an imidacloprid analogue, 1-(3-pyridylmethyl)-2-nitroimino-imidazolidine.
Autorzy:: Zhuang AX; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Zhang YX; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Zhang H; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Liu ZW; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China. .; Pokaż więcej
Źródło:: Insect science [Insect Sci] 2016 Oct; Vol. 23 (5), pp. 688-94. Date of Electronic Publication: 2015 May 19.
Typ publikacji:: Journal Article
MeSH Terms:: Hemiptera/*metabolism
Imidazoles/*pharmacology
Insecticides/*pharmacology
Nicotinic Antagonists/*pharmacology
Nitro Compounds/*pharmacology
Animals ; Dihydro-beta-Erythroidine/pharmacology ; Hemiptera/genetics ; Insecticide Resistance ; Mutation ; Nymph/genetics ; Nymph/metabolism ; Oocytes ; Receptors, Nicotinic/metabolism ; Xenopus

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Skocz do pozycji: 11.

Tytuł:: Nicotinic α4 Receptor-Mediated Cholinergic Influences on Food Intake and Activity Patterns in Hypothalamic Circuits.
Autorzy:: García AP; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom; Laboratory of Molecular Neurobiology, Biomedical Research Institute (BIOMED) UCA-CONICET, Faculty of Medical Sciences, Catholic University of Argentina, Buenos Aires, Argentina.
Aitta-aho T; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom.
Schaaf L; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom.
Heeley N; Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
Heuschmid L; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom.
Bai Y; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom; Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Barrantes FJ; Laboratory of Molecular Neurobiology, Biomedical Research Institute (BIOMED) UCA-CONICET, Faculty of Medical Sciences, Catholic University of Argentina, Buenos Aires, Argentina.
Apergis-Schoute J; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom; Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Aug 06; Vol. 10 (8), pp. e0133327. Date of Electronic Publication: 2015 Aug 06 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Eating/*physiology
Hypothalamus/*metabolism
Motor Activity/*physiology
Neurons/*metabolism
Receptors, Nicotinic/*metabolism
Animals ; Dihydro-beta-Erythroidine/pharmacology ; Eating/drug effects ; Hypothalamus/drug effects ; Male ; Motor Activity/drug effects ; Neural Pathways/drug effects ; Neural Pathways/metabolism ; Neurons/drug effects ; Nicotinic Antagonists/pharmacology ; Orexins/metabolism ; Oxytocin/metabolism ; Rats ; Rats, Wistar ; Tyrosine 3-Monooxygenase/metabolism

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Skocz do pozycji: 12.

Tytuł:: Novel fast adapting interneurons mediate cholinergic-induced fast GABAA inhibitory postsynaptic currents in striatal spiny neurons.
Autorzy:: Faust TW; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA.
Assous M; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA.
Shah F; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA.
Tepper JM; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA.
Koós T; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2015 Jul; Vol. 42 (2), pp. 1764-74. Date of Electronic Publication: 2015 May 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Adaptation, Physiological/*physiology
Cholinergic Agents/*pharmacology
Corpus Striatum/*cytology
Fasting/*physiology
GABAergic Neurons/*physiology
Neurons/*drug effects
Synaptic Potentials/*physiology
Animals ; Bacterial Proteins/genetics ; Channelrhodopsins ; Choline O-Acetyltransferase/metabolism ; Dihydro-beta-Erythroidine/pharmacology ; GABAergic Neurons/drug effects ; Humans ; In Vitro Techniques ; Luminescent Proteins/genetics ; Mice ; Mice, Transgenic ; Mutation/genetics ; Nerve Growth Factor/pharmacology ; Patch-Clamp Techniques ; Striatonigral Degeneration ; Synaptic Potentials/drug effects

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Skocz do pozycji: 13.

Tytuł:: Anxiolytic-like and anxiogenic-like effects of nicotine are regulated via diverse action at β2*nicotinic acetylcholine receptors.
Autorzy:: Anderson SM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Brunzell DH; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2015 Jun; Vol. 172 (11), pp. 2864-77. Date of Electronic Publication: 2015 Mar 24.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Anti-Anxiety Agents/*pharmacology
Anxiety/*chemically induced
Behavior, Animal/*drug effects
Nicotine/*pharmacology
Nicotinic Agonists/*pharmacology
Nicotinic Antagonists/*pharmacology
Receptors, Nicotinic/*drug effects
Animals ; Anxiety/genetics ; Azetidines/pharmacology ; Dihydro-beta-Erythroidine/pharmacology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pyridines/pharmacology ; Receptors, Nicotinic/genetics