Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors.
Autorzy:
Kumar P; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany. Scholze P; Department of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Vienna, Austria. Fronius M; Department of Physiology and HeartOtago, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand. Krasteva-Christ G; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany. Hollenhorst MI; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2020 Dec; Vol. 177 (24), pp. 5595-5608. Date of Electronic Publication: 2020 Nov 09.
Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro-β-erythroidine in nicotine-tolerant mice.
Autorzy:
de Moura FB; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Behavioral Biology Program, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Wilkerson JL; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, USA. McMahon LR; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, USA.
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Źródło:
Brain and behavior [Brain Behav] 2020 Apr; Vol. 10 (4), pp. e01581. Date of Electronic Publication: 2020 Feb 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor.
Autorzy:
Yu R; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Tae HS; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, NSW, Australia. Xu Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Craik DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia. Adams DJ; Illawarra Health and Medical Research Institute (IHMRI), University of Wollongong, Wollongong, NSW, Australia. Jiang T; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Kaas Q; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 Aug; Vol. 176 (15), pp. 2750-2763. Date of Electronic Publication: 2019 Jun 07.
Differential effects of α4β2 nicotinic receptor antagonists and partial-agonists on contextual fear extinction in male C57BL/6 mice.
Autorzy:
Kutlu MG; The Department of Biobehavioral Health, Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA, 16801, USA. . Tumolo JM; Department of Psychology, Temple University, Philadelphia, PA, USA. Cann C; The Department of Biobehavioral Health, Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA, 16801, USA. Gould TJ; The Department of Biobehavioral Health, Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA, 16801, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2018 Apr; Vol. 235 (4), pp. 1211-1219. Date of Electronic Publication: 2018 Jan 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury.
Autorzy:
Kiguchi N; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan. . Kobayashi D; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan. Saika F; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan. Matsuzaki S; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan. Kishioka S; Department of Pharmacology, Wakayama Medical University, 811-1 Kimiidera, Wakayama city, Wakayama, 641-0012, Japan.
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2018 Mar 27; Vol. 15 (1), pp. 96. Date of Electronic Publication: 2018 Mar 27.
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Autorzy:
de Moura FB; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3900, USA. McMahon LR; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3900, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2017 Mar; Vol. 234 (5), pp. 781-792. Date of Electronic Publication: 2016 Dec 27.
Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells.
Autorzy:
Qian J; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America. Mummalaneni SK; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America. Alkahtani RM; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America. Mahavadi S; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America. Murthy KS; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America. Grider JR; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America. Lyall V; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, 23219, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Nov 15; Vol. 11 (11), pp. e0166565. Date of Electronic Publication: 2016 Nov 15 (Print Publication: 2016).
The insecticidal activity and action mode of an imidacloprid analogue, 1-(3-pyridylmethyl)-2-nitroimino-imidazolidine.
Autorzy:
Zhuang AX; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China. Zhang YX; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China. Zhang H; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China. Liu ZW; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing, China. .
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Źródło:
Insect science [Insect Sci] 2016 Oct; Vol. 23 (5), pp. 688-94. Date of Electronic Publication: 2015 May 19.
Nicotinic α4 Receptor-Mediated Cholinergic Influences on Food Intake and Activity Patterns in Hypothalamic Circuits.
Autorzy:
García AP; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom; Laboratory of Molecular Neurobiology, Biomedical Research Institute (BIOMED) UCA-CONICET, Faculty of Medical Sciences, Catholic University of Argentina, Buenos Aires, Argentina. Aitta-aho T; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom. Schaaf L; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom. Heeley N; Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom. Heuschmid L; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom. Bai Y; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom; Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China. Barrantes FJ; Laboratory of Molecular Neurobiology, Biomedical Research Institute (BIOMED) UCA-CONICET, Faculty of Medical Sciences, Catholic University of Argentina, Buenos Aires, Argentina. Apergis-Schoute J; Department of Pharmacology, University of Cambridge; Cambridge, United Kingdom; Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
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Źródło:
PloS one [PLoS One] 2015 Aug 06; Vol. 10 (8), pp. e0133327. Date of Electronic Publication: 2015 Aug 06 (Print Publication: 2015).
Novel fast adapting interneurons mediate cholinergic-induced fast GABAA inhibitory postsynaptic currents in striatal spiny neurons.
Autorzy:
Faust TW; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA. Assous M; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA. Shah F; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA. Tepper JM; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA. Koós T; Center for Molecular and Behavioral Neuroscience, Rutgers, the State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA.
Anxiolytic-like and anxiogenic-like effects of nicotine are regulated via diverse action at β2*nicotinic acetylcholine receptors.
Autorzy:
Anderson SM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. Brunzell DH; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2015 Jun; Vol. 172 (11), pp. 2864-77. Date of Electronic Publication: 2015 Mar 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
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