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Wyszukujesz frazę ""Dimensionality"" wg kryterium: Temat


Tytuł :
Spatial rank-based multifactor dimensionality reduction to detect gene-gene interactions for multivariate phenotypes.
Autorzy :
Park M; Department of Preventive Medicine, Eulji University, Daejeon, 34824, Republic of Korea.
Jeong HB; Department of Statistics, Korea University, Seoul, 02841, Republic of Korea.
Lee JH; Department of Statistics, Korea University, Seoul, 02841, Republic of Korea.
Park T; Department of Statistics, Seoul National University, Seoul, 08826, Republic of Korea. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Oct 04; Vol. 22 (1), pp. 480. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*
Multifactor Dimensionality Reduction*
Algorithms ; Computer Simulation ; Epistasis, Genetic ; Models, Genetic ; Phenotype ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
A Belief Degree-Associated Fuzzy Multifactor Dimensionality Reduction Framework for Epistasis Detection.
Autorzy :
Rahaman S; Department of Computer Science, College of Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong. .
Wong KC; Department of Computer Science, College of Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong.
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2212, pp. 307-323.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
Fuzzy Logic*
Multifactor Dimensionality Reduction*
Multifactorial Inheritance*
Software*
Coronary Artery Disease/*genetics
Algorithms ; Databases, Genetic ; Datasets as Topic ; Humans ; Models, Genetic ; Polymorphism, Single Nucleotide ; Uncertainty
Czasopismo naukowe
Tytuł :
Association between polygenetic risk scores related to sarcopenia risk and their interactions with regular exercise in a large cohort of Korean adults.
Autorzy :
Park S; Dept. of Food and Nutrition, Obesity/Diabetes Research Center, Hoseo University, Asan, South Korea. Electronic address: .
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Źródło :
Clinical nutrition (Edinburgh, Scotland) [Clin Nutr] 2021 Oct; Vol. 40 (10), pp. 5355-5364. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exercise*
Hand Strength*
Polymorphism, Single Nucleotide*
Metabolic Syndrome/*epidemiology
Sarcopenia/*epidemiology
Sarcopenia/*genetics
Aged ; Cohort Studies ; Energy Intake ; Fatty Acid Desaturases/genetics ; Female ; Guanine Nucleotide Exchange Factors/genetics ; Hospitals, Urban ; Humans ; KCNQ Potassium Channels/genetics ; Male ; Middle Aged ; Multifactor Dimensionality Reduction ; Muscle, Skeletal ; Myosins/genetics ; Receptors, LDL/genetics ; Republic of Korea/epidemiology ; Risk Factors
Czasopismo naukowe
Tytuł :
Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction.
Autorzy :
Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Department of Allergy and Rheumatology, Graduate School of Medicine, the University of Tokyo, Tokyo, 113-8655, Japan.
Hirata J; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.; Pharmaceutical Discovery Research Laboratories, TEIJIN PHARMA LIMITED, Hino, 191-8512, Japan.
Kanai M; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Suzuki K; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.
Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, 812-8582, Japan.
Lai Too C; Allergy and Immunology Research Center, Institute for Medical Research, Ministry of Health Malaysia, 40170, Setia Alam, Malaysia.; Division of Rheumatology, Department of Medicine, Karolinska Institutet and Karolinska University Hospital, 17177, Stockholm, Sweden.
Arayssi T; Department of Internal Medicine, Weill Cornell Medicine-Qatar, Education City, Doha, 24144, Qatar.
Hammoudeh M; Department of Internal Medicine, Hamad Medical Corporation, Doha, 3050, Qatar.
Al Emadi S; Department of Internal Medicine, Hamad Medical Corporation, Doha, 3050, Qatar.
Masri BK; Department of Internal Medicine, Jordan Hospital, Amman, 520248, Jordan.
Halabi H; Rheumatology Division, Department of Internal Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, H45X+P6, Saudi Arabia.
Badsha H; Dr. Humeira Badsha Medical Center, Emirates Hospital, Dubai, 391203, United Arab Emirates.
Uthman IW; Department of Rheumatology, American University of Beirut, Beirut, 11-0236, Lebanon.
Saxena R; Center for Genomic Medicine, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Program in Medical and Population Genetics Broad Institute, Cambridge, MA, 02142, USA.
Padyukov L; Division of Rheumatology, Department of Medicine, Karolinska Institutet and Karolinska University Hospital, 17177, Stockholm, Sweden.
Hirata M; Laboratory of Genome Technology, Institute of Medical Science, the University of Tokyo, Tokyo, 108-8639, Japan.
Matsuda K; Department of Computational Biology and Medical Sciences, Graduate school of Frontier Sciences, the University of Tokyo, Tokyo, 108-8639, Japan.
Murakami Y; Division of Molecular Pathology, Institute of Medical Science, the University of Tokyo, Tokyo, 108-8639, Japan.
Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Tokyo, 108-8639, Japan.
Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan. .; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, 565-0871, Japan. .; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, 565-0871, Japan. .
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Źródło :
Nature communications [Nat Commun] 2020 Mar 26; Vol. 11 (1), pp. 1569. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Genetics, Population*
Multifactor Dimensionality Reduction*
Asian Continental Ancestry Group/*genetics
Multifactorial Inheritance/*genetics
Base Sequence ; Biological Specimen Banks ; Humans ; Japan ; Phenotype ; Principal Component Analysis ; Risk Factors
Czasopismo naukowe
Tytuł :
ERAP1 polymorphisms interactions and their association with Behçet's disease susceptibly: Application of Model-Based Multifactor Dimension Reduction Algorithm (MB-MDR).
Autorzy :
Riahi P; Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Kazemnejad A; Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Mostafaei S; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Meguro A; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Mizuki N; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Ashraf-Ganjouei A; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Javinani A; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Faezi ST; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Shahram F; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mahmoudi M; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Inflammation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
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Źródło :
PloS one [PLoS One] 2020 Feb 05; Vol. 15 (2), pp. e0227997. Date of Electronic Publication: 2020 Feb 05 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Genetic Association Studies*
Genetic Predisposition to Disease*
Models, Genetic*
Multifactor Dimensionality Reduction*
Aminopeptidases/*genetics
Behcet Syndrome/*genetics
Minor Histocompatibility Antigens/*genetics
Polymorphism, Single Nucleotide/*genetics
Adult ; Entropy ; Female ; Gene Frequency/genetics ; Gene Regulatory Networks ; Humans ; Iran ; Male
Czasopismo naukowe
Tytuł :
A data-driven dimensionality-reduction algorithm for the exploration of patterns in biomedical data.
Autorzy :
Islam MT; Department of Radiation Oncology, Stanford University, Stanford, CA, USA.
Xing L; Department of Radiation Oncology, Stanford University, Stanford, CA, USA. .
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Źródło :
Nature biomedical engineering [Nat Biomed Eng] 2021 Jun; Vol. 5 (6), pp. 624-635. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Datasets as Topic*
Biomedical Research/*statistics & numerical data
Multifactor Dimensionality Reduction/*statistics & numerical data
Electroencephalography/statistics & numerical data ; Humans ; Protein Biosynthesis ; Sequence Analysis, RNA/statistics & numerical data ; Single-Cell Analysis/statistics & numerical data ; Tomography, X-Ray Computed/statistics & numerical data
Czasopismo naukowe
Tytuł :
Designing a hybrid dimension reduction for improving the performance of Amharic news document classification.
Autorzy :
Endalie D; Factuality of computing and Informatics, Jimma institute of technology, Jimma, Ethiopia.
Tegegne T; Factuality of computing, Bahir Dar Institute of Technology, Bahir Dar, Ethiopia.
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Źródło :
PloS one [PLoS One] 2021 May 21; Vol. 16 (5), pp. e0251902. Date of Electronic Publication: 2021 May 21 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Information Technology*
Support Vector Machine*
Data Mining/*methods
Linguistics/*statistics & numerical data
Multifactor Dimensionality Reduction/*statistics & numerical data
Datasets as Topic ; Ethiopia ; Humans ; Language ; Principal Component Analysis
Czasopismo naukowe
Tytuł :
Genetic interactions effects for cancer disease identification using computational models: a review.
Autorzy :
Manavalan R; Department of Computer Science, Arignar Anna Government Arts College, Villupuram, Tamil Nadu, 605602, India. .
Priya S; Computer Science, Arignar Anna Government Arts College, Villupuram, Tamil Nadu, India.
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Źródło :
Medical & biological engineering & computing [Med Biol Eng Comput] 2021 Apr; Vol. 59 (4), pp. 733-758. Date of Electronic Publication: 2021 Apr 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epistasis, Genetic*
Neoplasms*/genetics
Computational Biology ; Genome-Wide Association Study ; Humans ; Models, Genetic ; Multifactor Dimensionality Reduction ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Interaction Effects of Gene Polymorphisms and Obesity on Nonalcoholic Fatty Liver Disease.
Autorzy :
Sun XY; Department of Epidemiology and Statistic, School of Public Health and Management, Ningxia Medical University, Yinchuan 750004, Ningxia, China.
He ZQ; Department of Epidemiology and Statistic, School of Public Health and Management, Ningxia Medical University, Yinchuan 750004, Ningxia, China.
Wang LQ; Department of Epidemiology and Statistic, School of Public Health and Management, Ningxia Medical University, Yinchuan 750004, Ningxia, China.
Wang ZZ; Department of Epidemiology and Statistic, School of Public Health and Management, Ningxia Medical University, Yinchuan 750004, Ningxia, China.
Bai FH; Department of gastroenterology at Ningxia Hui Autonomous Region People's Hospital, Yinchuan 750021, Ningxia, China.
You YJ; Department of gastroenterology at Ningxia Hui Autonomous Region People's Hospital, Yinchuan 750021, Ningxia, China.
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Źródło :
Biomedical and environmental sciences : BES [Biomed Environ Sci] 2019 Oct; Vol. 32 (10), pp. 793-796.
Typ publikacji :
Letter
MeSH Terms :
Multifactor Dimensionality Reduction*
Polymorphism, Genetic*
Non-alcoholic Fatty Liver Disease/*genetics
Obesity/*etiology
Aged ; Aged, 80 and over ; China ; Female ; Humans ; Male ; Middle Aged ; Models, Theoretical ; Non-alcoholic Fatty Liver Disease/etiology
Opinia redakcyjna
Tytuł :
First-Order Correction of Statistical Significance for Screening Two-Way Epistatic Interactions.
Autorzy :
Cheng L; University of Waterloo, Waterloo, Ontario, Canada.
Zhu M; University of Waterloo, Waterloo, Ontario, Canada. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2212, pp. 181-190.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Epistasis, Genetic*
Genetic Association Studies*
Models, Genetic*
Polymorphism, Single Nucleotide*
Computer Simulation ; Genotype ; Humans ; Multifactor Dimensionality Reduction ; Phenotype ; Statistics as Topic
Czasopismo naukowe
Tytuł :
Empowering individual trait prediction using interactions for precision medicine.
Autorzy :
Gola D; Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
König IR; Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Feb 18; Vol. 22 (1), pp. 74. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Precision Medicine*
Algorithms ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/genetics ; Humans ; Machine Learning ; Multifactor Dimensionality Reduction ; Power, Psychological
Czasopismo naukowe
Tytuł :
Benchmarking joint multi-omics dimensionality reduction approaches for the study of cancer.
Autorzy :
Cantini L; Computational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Ecole Normale Supérieure, Université PSL, 75005, Paris, France. .
Zakeri P; Aix Marseille Univ, INSERM, MMG, Marseille Medical Genetics, CNRS, Turing Center for Living Systems, Marseille, France.; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium and Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Hernandez C; Computational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Ecole Normale Supérieure, Université PSL, 75005, Paris, France.; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
Naldi A; Computational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Ecole Normale Supérieure, Université PSL, 75005, Paris, France.; Inria Saclay Ile de France, EP Lifeware, Palaiseau, France.
Thieffry D; Computational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Ecole Normale Supérieure, Université PSL, 75005, Paris, France.
Remy E; Aix Marseille Univ, CNRS, Centrale Marseille, I2M, Turing Center for Living Systems, Marseille, France.
Baudot A; Aix Marseille Univ, INSERM, MMG, Marseille Medical Genetics, CNRS, Turing Center for Living Systems, Marseille, France. .; Barcelona Supercomputing Center (BSC), Barcelona, 08034, Spain. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 05; Vol. 12 (1), pp. 124. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Gene Expression Regulation, Neoplastic*
Computational Biology/*methods
Neoplasm Proteins/*genetics
Neoplasms/*genetics
Benchmarking ; Cell Line, Tumor ; Datasets as Topic ; Gene Ontology ; Humans ; Molecular Sequence Annotation ; Multifactor Dimensionality Reduction ; Neoplasm Proteins/metabolism ; Neoplasms/diagnosis ; Neoplasms/mortality ; Neoplasms/pathology ; Reproducibility of Results ; Single-Cell Analysis ; Survival Analysis
Czasopismo naukowe
Tytuł :
Interaction Effects of Plasma Vitamins A, E, D, B9, and B12 and Tobacco Exposure in Urothelial Bladder Cancer: A Multifactor Dimensionality Reduction Analysis.
Autorzy :
Mostafaei S; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Epidemiology and Biostatistics Unit, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Riahi P; Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
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Źródło :
Nutrition and cancer [Nutr Cancer] 2021; Vol. 73 (8), pp. 1539-1540. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Letter; Comment
MeSH Terms :
Urinary Bladder Neoplasms*
Vitamins*
Humans ; Multifactor Dimensionality Reduction ; Tobacco ; Vitamin A
Opinia redakcyjna
Tytuł :
Epistasis Analysis: Classification Through Machine Learning Methods.
Autorzy :
Liu L; Department of Computer Science, City University of Hong Kong, Kowloon Tong, Hong Kong.
Wong KC; Department of Computer Science, City University of Hong Kong, Kowloon Tong, Hong Kong. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2212, pp. 337-345.
Typ publikacji :
Journal Article
MeSH Terms :
Epistasis, Genetic*
Machine Learning*
Models, Genetic*
Polymorphism, Single Nucleotide*
Multifactorial Inheritance/*genetics
Computational Biology/methods ; Datasets as Topic ; Humans ; Multifactor Dimensionality Reduction ; Software
Czasopismo naukowe
Tytuł :
Generalized multifactor dimensionality reduction approaches to identification of genetic interactions underlying ordinal traits.
Autorzy :
Hou TT; Biostatistics Program, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.; Arkansas Children's Research Institute, Little Rock, Arkansas.; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
Lin F; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
Bai S; Biostatistics Program, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.; Arkansas Children's Research Institute, Little Rock, Arkansas.
Cleves MA; Biostatistics Program, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.; Arkansas Children's Research Institute, Little Rock, Arkansas.
Xu HM; Biostatistics Program, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.; Arkansas Children's Research Institute, Little Rock, Arkansas.; Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.
Lou XY; Biostatistics Program, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.; Arkansas Children's Research Institute, Little Rock, Arkansas.; Arkansas Children's Nutrition Center, Little Rock, Arkansas.
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Źródło :
Genetic epidemiology [Genet Epidemiol] 2019 Feb; Vol. 43 (1), pp. 24-36. Date of Electronic Publication: 2018 Nov 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Epistasis, Genetic*
Multifactor Dimensionality Reduction*
Quantitative Trait, Heritable*
Atherosclerosis/genetics ; Computer Simulation ; Ethnic Groups/genetics ; Gene Regulatory Networks ; Genotype ; Humans ; Models, Genetic ; Phenotype ; Principal Component Analysis ; Probability ; ROC Curve ; Risk Factors
Czasopismo naukowe
Tytuł :
Exploring gene-gene interaction in family-based data with an unsupervised machine learning method: EPISFA.
Autorzy :
Xiang X; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Wang S; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Liu T; Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China.
Wang M; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Li J; Department of Clinical Medicine, School of Medicine, Peking University, Beijing, China.
Jiang J; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Wu T; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Hu Y; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
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Źródło :
Genetic epidemiology [Genet Epidemiol] 2020 Nov; Vol. 44 (8), pp. 811-824. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Epistasis, Genetic*
Unsupervised Machine Learning*
Case-Control Studies ; Factor Analysis, Statistical ; Family ; Humans ; Ischemic Stroke/genetics ; Linkage Disequilibrium/genetics ; Models, Genetic ; Multifactor Dimensionality Reduction
Czasopismo naukowe
Tytuł :
cnnAlpha: Protein disordered regions prediction by reduced amino acid alphabets and convolutional neural networks.
Autorzy :
Oberti M; School of Systems Biology, George Mason University, Manassas, Virginia, USA.; Novartis Institutes for BioMedical Research, Cambridge, Massachussets, USA.
Vaisman II; School of Systems Biology, George Mason University, Manassas, Virginia, USA.
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Źródło :
Proteins [Proteins] 2020 Nov; Vol. 88 (11), pp. 1472-1481. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Machine Learning*
Neural Networks, Computer*
Computational Biology/*methods
Data Mining/*statistics & numerical data
Intrinsically Disordered Proteins/*chemistry
Amino Acid Sequence ; Area Under Curve ; Benchmarking ; Datasets as Topic ; Humans ; Multifactor Dimensionality Reduction ; ROC Curve ; Sequence Analysis, Protein
Czasopismo naukowe
Tytuł :
A new efficient method to detect genetic interactions for lung cancer GWAS.
Autorzy :
Luyapan J; Quantitative Biomedical Science Program, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA.
Ji X; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA.
Li S; Quantitative Biomedical Science Program, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA.
Xiao X; Institute for Clinical and Translational Research, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Zhu D; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA.; Institute for Clinical and Translational Research, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Duell EJ; Unit of Nutrition and Cancer, Catalan Institute of Oncology (ICO-IDIBELL), 08908, Barcelona, Spain.
Christiani DC; Department of Environmental Health, Harvard School of Public Health, Boston, MA, 02115, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, 02115, USA.
Schabath MB; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.
Arnold SM; Markey Cancer Center, University of Kentucky, First Floor, 800 Rose Street, Lexington, KY, 40508, USA.
Zienolddiny S; National Institute of Occupational Health, 0033 Gydas vei 8, 0033, Oslo, Norway.
Brunnström H; Laboratory Medicine Region Skåne, Department of Clinical Sciences Lund, Pathology, Lund University, Lund, Sweden.
Melander O; Department of Clinical Sciences, Lund University, Malmö, Sweden.
Thornquist MD; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
MacKenzie TA; Quantitative Biomedical Science Program, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA.
Amos CI; Quantitative Biomedical Science Program, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA. .; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA. .; Institute for Clinical and Translational Research, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA. .
Gui J; Quantitative Biomedical Science Program, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA. .; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, One Medical Center Dr., Lebanon, NH, 03756, USA. .
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Źródło :
BMC medical genomics [BMC Med Genomics] 2020 Oct 30; Vol. 13 (1), pp. 162. Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Algorithms*
Gene Expression Regulation, Neoplastic*
Genome-Wide Association Study*
Polymorphism, Single Nucleotide*
Biomarkers, Tumor/*genetics
Computational Biology/*methods
Lung Neoplasms/*mortality
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Case-Control Studies ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Multifactor Dimensionality Reduction ; Prognosis ; Survival Rate ; Young Adult
Czasopismo naukowe
Tytuł :
Detection of epistasis between ACTN3 and SNAP-25 with an insight towards gymnastic aptitude identification.
Autorzy :
Płóciennik ŁA; Department of Physical Education, Academy of Physical Education and Sport in Gdansk, Gdansk, Pomorskie Voivodeship, Poland.; FitnessFitback, Pomorskie Voivodeship, Poland.
Zaucha J; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, Freising, Germany.
Zaucha JM; Department of Haematology and Transplantation, Medical University of Gdansk, Gdansk, Pomorskie Voivodeship, Poland.
Łukaszuk K; Faculty of Health Sciences with Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Gdansk, Pomorskie Voivodeship, Poland.
Jóźwicki M; Department of Architecture and Design, Academy of Fine Arts, Gdansk, Pomorskie Voivodeship, Poland.
Płóciennik M; FitnessFitback, Pomorskie Voivodeship, Poland.
Cięszczyk P; Department of Physical Education, Academy of Physical Education and Sport in Gdansk, Gdansk, Pomorskie Voivodeship, Poland.
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Źródło :
PloS one [PLoS One] 2020 Aug 31; Vol. 15 (8), pp. e0237808. Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aptitude*
Epistasis, Genetic*
Actinin/*genetics
Gymnastics/*physiology
Synaptosomal-Associated Protein 25/*genetics
Adult ; Alleles ; Area Under Curve ; Databases, Genetic ; Entropy ; Female ; Genetic Markers ; Humans ; Logistic Models ; Male ; Models, Genetic ; Multifactor Dimensionality Reduction ; Polymorphism, Single Nucleotide/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Multipopulation harmony search algorithm for the detection of high-order SNP interactions.
Autorzy :
Tuo S; School of Computer Science and Technology, Xi'an University of Posts and Telecommunications, Xi'an, Shaanxi 710121, China.
Liu H; School of Computer Science and Technology, Xi'an University of Posts and Telecommunications, Xi'an, Shaanxi 710121, China.
Chen H; School of Computer Science and Technology, Xi'an University of Posts and Telecommunications, Xi'an, Shaanxi 710121, China.
Pokaż więcej
Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2020 Aug 15; Vol. 36 (16), pp. 4389-4398.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epistasis, Genetic*
Polymorphism, Single Nucleotide*
Algorithms ; Bayes Theorem ; Multifactor Dimensionality Reduction
Czasopismo naukowe

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