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Tytuł :
Endonuclease V from the archaeon Thermococcus kodakarensis is an inosine-specific ribonuclease.
Autorzy :
Shiraishi M; Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan.
Hidaka M; Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan.
Iwai S; Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan.
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Źródło :
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2022 Feb 24; Vol. 86 (3), pp. 313-320.
Typ publikacji :
Journal Article
MeSH Terms :
Deoxyribonuclease (Pyrimidine Dimer)*
Viral Proteins*
Czasopismo naukowe
Tytuł :
Mycobacterium tuberculosis Endonuclease VIII 2 (Nei2) forms a prereplicative BER complex with DnaN: Identification, characterization, and disruption of complex formation.
Autorzy :
Lata K; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Vishwakarma J; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Kumar S; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Khanam T; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Ramachandran R; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
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Źródło :
Molecular microbiology [Mol Microbiol] 2022 Feb; Vol. 117 (2), pp. 320-333. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Deoxyribonuclease (Pyrimidine Dimer)*/genetics
Mycobacterium tuberculosis*/genetics
Amino Acid Motifs ; DNA Repair
Czasopismo naukowe
Tytuł :
Mouse Embryonic Fibroblasts Isolated From Nthl1 D227Y Knockin Mice Exhibit Defective DNA Repair and Increased Genome Instability.
Autorzy :
Marsden CG; Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, University of Vermont, Burlington, VT 05405, USA-0068.
Das L; Department of Cellular and Molecular Medicine, University of Arizona Cancer Center, Tucson, AZ 85724-5024, USA.
Nottoli TP; Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
Kathe SD; Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, University of Vermont, Burlington, VT 05405, USA-0068.
Doublié S; Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, University of Vermont, Burlington, VT 05405, USA-0068.
Wallace SS; Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, University of Vermont, Burlington, VT 05405, USA-0068.
Sweasy JB; Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, University of Vermont, Burlington, VT 05405, USA-0068; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510; Department of Cellular and Molecular Medicine, University of Arizona Cancer Center, Tucson, AZ 85724-5024, USA. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2022 Jan; Vol. 109, pp. 103247. Date of Electronic Publication: 2021 Nov 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Repair*
Genomic Instability*
Mutation, Missense*
Deoxyribonuclease (Pyrimidine Dimer)/*metabolism
Fibroblasts/*enzymology
Animals ; DNA/drug effects ; DNA/metabolism ; DNA Damage ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Fibroblasts/metabolism ; Gene Knock-In Techniques ; Mice ; Mice, Mutant Strains ; Mutagens/toxicity ; Oxidative Stress ; Vitamin K 3/toxicity
Czasopismo naukowe
Tytuł :
Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis.
Autorzy :
Carroll BL; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
Zahn KE; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
Hanley JP; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
Wallace SS; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
Dragon JA; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
Doublié S; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Dec 16; Vol. 49 (22), pp. 13165-13178.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Catalytic Domain*
DNA Repair*
Protein Domains*
DNA/*chemistry
Deoxyribonuclease (Pyrimidine Dimer)/*chemistry
Amino Acid Sequence ; Biocatalysis ; DNA/genetics ; DNA/metabolism ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Deoxyribonuclease (Pyrimidine Dimer)/metabolism ; Humans ; Models, Molecular ; Mutation ; Nucleic Acid Conformation ; Protein Binding ; Protein Conformation ; Pyrimidines/metabolism ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA.
Autorzy :
Endo M; Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan.
Kim JI; Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan.
Shioi NA; Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Iwai S; Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan.
Kuraoka I; Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
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Źródło :
Open biology [Open Biol] 2021 Oct; Vol. 11 (10), pp. 210148. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis/*metabolism
Deoxyribonuclease (Pyrimidine Dimer)/*metabolism
Inosine/*chemistry
RNA, Plant/*genetics
Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Binding Sites ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Gene Expression Regulation, Plant ; RNA Editing ; RNA, Plant/chemistry ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration.
Autorzy :
Kong XY; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Huse C; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Yang K; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Øgaard J; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Berges N; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Vik ES; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Nawaz MS; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Quiles-Jiménez A; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Abbas A; Ostfold Hospital Trust Kalnes Norway.
Gregersen I; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Holm S; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Bjerkli V; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Rashidi A; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Fladeby C; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Suganthan R; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Sagen EL; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Skjelland M; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.; Department of Neurology Oslo University Hospital, Rikshospitalet Oslo Norway.
Lång A; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Bøe SO; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Bjørås M; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.; Department of Clinical and Molecular Medicine Norwegian University of Science and Technology Trondheim Norway.
Aukrust P; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.; Section of Clinical Immunology and Infectious Diseases Oslo University Hospital, Rikshospitalet Oslo Norway.; K.G. Jebsen, The Faculty of Health Sciences The Arctic University of Tromsø Tromsø Norway.
Alseth I; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Halvorsen B; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Dahl TB; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2021 Jul 20; Vol. 10 (14), pp. e020656. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Aorta, Thoracic/*pathology
Atherosclerosis/*genetics
Chemokine CCL2/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Monocytes/*metabolism
RNA/*genetics
Aged ; Animals ; Aorta, Thoracic/metabolism ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Chemokine CCL2/biosynthesis ; Cytokines ; Deoxyribonuclease (Pyrimidine Dimer)/biosynthesis ; Disease Models, Animal ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/pathology ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Dynamics and Conformational Changes in Human NEIL2 DNA Glycosylase Analyzed by Hydrogen/Deuterium Exchange Mass Spectrometry.
Autorzy :
Zhdanova PV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibisk, Russia; Novosibirsk State University, Novosibisk, Russia.
Ishchenko AA; Groupe 'Réparation de lADN', Equipe Labellisée par la Ligue Nationale contre le Cancer, CNRS UMR 8200, Univ. Paris-Sud, Université Paris-Saclay, Villejuif F-94805, France; Gustave Roussy, Université Paris-Saclay, Villejuif F-94805, France.
Chernonosov AA; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibisk, Russia.
Zharkov DO; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibisk, Russia; Novosibirsk State University, Novosibisk, Russia.
Koval VV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibisk, Russia; Novosibirsk State University, Novosibisk, Russia. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2022 Jan 30; Vol. 434 (2), pp. 167334. Date of Electronic Publication: 2021 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Deuterium*
Hydrogen*
DNA Glycosylases/*chemistry
DNA-(Apurinic or Apyrimidinic Site) Lyase/*chemistry
DNA ; DNA Damage ; DNA Glycosylases/genetics ; DNA Repair ; DNA-(Apurinic or Apyrimidinic Site) Lyase/genetics ; DNA-Binding Proteins ; Deoxyribonuclease (Pyrimidine Dimer)/chemistry ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Humans ; Mass Spectrometry ; Mimiviridae/genetics ; Models, Molecular ; Protein Conformation
Czasopismo naukowe
Tytuł :
In Vitro Construction of Large-scale DNA Libraries from Fragments Containing Random Regions using Deoxyinosine-containing Oligonucleotides and Endonuclease V.
Autorzy :
Yamamoto Y; Graduate School of Science and Engineering, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama City, 338-8570, Japan.
Terai T; Graduate School of Science and Engineering, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama City, 338-8570, Japan.
Kumachi S; Epsilon Molecular Engineering, Inc., 255 Shimo-okubo, Sakura-ku, Saitama City 338-8570, Saitama, Japan.
Nemoto N; Graduate School of Science and Engineering, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama City, 338-8570, Japan.; Epsilon Molecular Engineering, Inc., 255 Shimo-okubo, Sakura-ku, Saitama City 338-8570, Saitama, Japan.
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Źródło :
ACS combinatorial science [ACS Comb Sci] 2020 Apr 13; Vol. 22 (4), pp. 165-171. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Library*
DNA/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Inosine/*analogs & derivatives
Oligonucleotides/*genetics
Viral Proteins/*genetics
Combinatorial Chemistry Techniques ; DNA/chemistry ; Deoxyribonuclease (Pyrimidine Dimer)/chemistry ; Deoxyribonuclease (Pyrimidine Dimer)/metabolism ; Inosine/chemistry ; Inosine/genetics ; Oligonucleotides/chemistry ; Polymerase Chain Reaction ; Viral Proteins/chemistry ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis -Element in Response to 5-Formylcytosine and 5-Carboxycytosine.
Autorzy :
Müller N; Institute of Toxicology, University Medical Center Mainz, 55131 Mainz, Germany.
Ponkkonen E; Department of Chemistry and Biochemistry, Ludwig-Maximilians University Munich, 81377 Munich, Germany.
Carell T; Department of Chemistry and Biochemistry, Ludwig-Maximilians University Munich, 81377 Munich, Germany.
Khobta A; Institute of Toxicology, University Medical Center Mainz, 55131 Mainz, Germany.; Institute of Nutritional Sciences, Friedrich Schiller University Jena, 07743 Jena, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 13; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
CpG Islands*
DNA Damage*
DNA Repair*
Promoter Regions, Genetic*
Cytosine/*analogs & derivatives
Thymine DNA Glycosylase/*metabolism
DNA/metabolism ; DNA Demethylation ; DNA Methylation ; Deoxyribonuclease (Pyrimidine Dimer) ; Epigenesis, Genetic ; HeLa Cells ; Humans
Czasopismo naukowe
Tytuł :
POLE, POLD1, and NTHL1: the last but not the least hereditary cancer-predisposing genes.
Autorzy :
Magrin L; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Fanale D; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Brando C; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Fiorino A; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Corsini LR; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Sciacchitano R; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Filorizzo C; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Dimino A; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
Russo A; Section of Medical Oncology, Department of Surgical, Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy. .
Bazan V; Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, 90127, Palermo, Italy.
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Źródło :
Oncogene [Oncogene] 2021 Oct; Vol. 40 (40), pp. 5893-5901. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Polymerase II/*metabolism
DNA Polymerase III/*metabolism
Deoxyribonuclease (Pyrimidine Dimer)/*metabolism
Neoplasms/*genetics
Poly-ADP-Ribose Binding Proteins/*metabolism
Female ; Genetic Predisposition to Disease ; Humans ; Male
Czasopismo naukowe
Tytuł :
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Autorzy :
Kong XY; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.
Vik ES; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
Nawaz MS; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
Berges N; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
Dahl TB; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
Vågbø C; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Suganthan R; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
Segers F; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.
Holm S; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.
Quiles-Jiménez A; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, NO-0317 Oslo, Norway.
Gregersen I; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.
Fladeby C; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
Aukrust P; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, NO-0317 Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, NO-0424 Oslo, Norway.
Bjørås M; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Klungland A; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.; Department of Molecular Medicine, Institute of Basic Medical Sciences, University ofOslo, NO-0317 Oslo, Norway.
Halvorsen B; Research Institute of Internal Medicine, Oslo University Hospital HF, Rikshospitalet, NO-0424 Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, NO-0317 Oslo, Norway.
Alseth I; Department of Microbiology, Oslo University Hospital HF, Rikshospitalet and University of Oslo, NO-0424 Oslo, Norway.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 May 07; Vol. 48 (8), pp. 4463-4479.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Liver Neoplasms, Experimental/*genetics
Adenosine/metabolism ; Animals ; Antineoplastic Agents/pharmacology ; Carcinogenesis ; Cell Line ; Deoxyribonuclease (Pyrimidine Dimer)/metabolism ; Gene Expression ; Humans ; Inosine/metabolism ; Liver/metabolism ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/metabolism ; Liver Neoplasms, Experimental/pathology ; Mice, Knockout ; RNA Editing ; RNA, Transfer/metabolism ; Sequence Analysis, RNA ; Sorafenib/pharmacology
Czasopismo naukowe
Tytuł :
An Excimer Clamp for Measuring Damaged-Base Excision by the DNA Repair Enzyme NTH1.
Autorzy :
Jun YW; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
Wilson DL; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
Kietrys AM; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
Lotsof ER; Department of Chemistry, University of California, Davis, Davis, CA, 95616, USA.
Conlon SG; Department of Chemistry, University of California, Davis, Davis, CA, 95616, USA.
David SS; Department of Chemistry, University of California, Davis, Davis, CA, 95616, USA.
Kool ET; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 May 04; Vol. 59 (19), pp. 7450-7455. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Repair*
Deoxyribonuclease (Pyrimidine Dimer)/*chemistry
Antimutagenic Agents/pharmacology ; DNA Damage ; Deoxyribonuclease (Pyrimidine Dimer)/antagonists & inhibitors ; Drug Evaluation, Preclinical ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/pharmacology ; Humans ; Oxidation-Reduction ; Oxidative Stress ; Pyrimidines/chemistry
Czasopismo naukowe
Tytuł :
Förster Resonance Energy Transfer Based Biosensor for Targeting the hNTH1-YB1 Interface as a Potential Anticancer Drug Target.
Autorzy :
Senarisoy M; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
Barette C; Univ. Grenoble Alpes, CEA, INSERM, BGE, F-38000 Grenoble, France.
Lacroix F; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
De Bonis S; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
Stelter M; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
Hans F; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
Kleman JP; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
Fauvarque MO; Univ. Grenoble Alpes, CEA, INSERM, BGE, F-38000 Grenoble, France.
Timmins J; Univ. Grenoble Alpes, CEA, CNRS, IBS, F-38000 Grenoble, France.
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Źródło :
ACS chemical biology [ACS Chem Biol] 2020 Apr 17; Vol. 15 (4), pp. 990-1003. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*analysis
Biosensing Techniques/*methods
Deoxyribonuclease (Pyrimidine Dimer)/*antagonists & inhibitors
Protein Binding/*drug effects
Y-Box-Binding Protein 1/*antagonists & inhibitors
Antineoplastic Agents/pharmacology ; Cisplatin/pharmacology ; Deoxyribonuclease (Pyrimidine Dimer)/metabolism ; Drug Resistance, Neoplasm/drug effects ; Fluorescence Resonance Energy Transfer/methods ; Humans ; MCF-7 Cells ; Pilot Projects ; Small Molecule Libraries/analysis ; Small Molecule Libraries/pharmacology ; Y-Box-Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Autorzy :
Liu M; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Zhang J; Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.; Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen, China.
Zhu C; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Zhang X; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Xiao W; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Yan Y; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Liu L; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Zeng H; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Gao YQ; Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China. .; Institute of Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen, China. .; Beijing Advanced Innovation Center for Genomics, Peking University, Beijing, China. .; Biomedical Pioneering Innovation Center, Peking University, Beijing, China. .
Yi C; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. .; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China. .; Department of Chemical Biology and Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking University, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 05; Vol. 12 (1), pp. 4108. Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Triage*
DNA Glycosylases/*chemistry
DNA Glycosylases/*metabolism
DNA Repair/*physiology
Amino Acid Sequence ; Binding Sites ; Catalytic Domain ; DNA/chemistry ; DNA Damage ; DNA Glycosylases/genetics ; Deoxyribonuclease (Pyrimidine Dimer)/chemistry ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Deoxyribonuclease (Pyrimidine Dimer)/metabolism ; Humans ; Molecular Dynamics Simulation ; Mutation ; Protein Conformation ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Autorzy :
Wu J; Laboratory of Molecular Biology, NIDDK, NIH, Bethesda, MD 20892, USA.
Samara NL; Section on Biological Chemistry, NIDCR, NIH, Bethesda, MD 20892, USA.
Kuraoka I; Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Yang W; Laboratory of Molecular Biology, NIDDK, NIH, Bethesda, MD 20892, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2019 Oct 03; Vol. 76 (1), pp. 44-56.e3. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Repair*
Evolution, Molecular*
Bacterial Proteins/*metabolism
DNA, Bacterial/*metabolism
Deoxyribonuclease (Pyrimidine Dimer)/*metabolism
Inosine/*metabolism
RNA/*metabolism
Ribonuclease H/*metabolism
Animals ; Argonaute Proteins/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Catalysis ; DNA, Bacterial/chemistry ; DNA, Bacterial/genetics ; Deoxyribonuclease (Pyrimidine Dimer)/chemistry ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Humans ; Magnesium/metabolism ; Manganese/metabolism ; Mice ; Nucleic Acid Conformation ; Protein Conformation ; RNA/chemistry ; RNA/genetics ; Ribonuclease H/chemistry ; Ribonuclease H/genetics ; Structure-Activity Relationship ; Substrate Specificity
Czasopismo naukowe
Tytuł :
A Case of Multiple Adenomatous Colon Polyps and Meningiomas.
Autorzy :
Liu K; University of Texas Southwestern Medical School, Dallas, Texas.
Kupfer SS; Department of Medicine, University of Chicago, Chicago, Illinois.
Jain R; Texas Digestive Disease Consultants, Dallas, Texas. Electronic address: .
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Źródło :
Gastroenterology [Gastroenterology] 2021 Sep; Vol. 161 (3), pp. 811-813. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Case Reports
MeSH Terms :
Germ-Line Mutation*
Adenomatous Polyposis Coli/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Meningeal Neoplasms/*genetics
Meningioma/*genetics
Adenomatous Polyposis Coli/diagnosis ; Adult ; Biopsy ; Colonoscopy ; DNA Mutational Analysis ; Female ; Genetic Predisposition to Disease ; Humans ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/surgery ; Meningioma/diagnostic imaging ; Meningioma/surgery
Raport
Tytuł :
Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection.
Autorzy :
Cheng J; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
Siejka-Zielińska P; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
Liu Y; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
Chandran A; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
Kriaucionis S; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
Song CX; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 21; Vol. 49 (13), pp. e76.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Sequence Analysis, DNA/*methods
Animals ; Cells, Cultured ; Cost-Benefit Analysis ; CpG Islands ; Deoxyribonuclease (Pyrimidine Dimer) ; Embryonic Stem Cells/metabolism ; Genomics/methods ; Mice ; Sequence Analysis, DNA/economics ; Uracil-DNA Glycosidase
Czasopismo naukowe
Tytuł :
Ubiquitous membrane-bound DNase activity in podosomes and invadopodia.
Autorzy :
Pal K; Department of Physics and Astronomy, Iowa State University, Ames, IA.
Zhao Y; Department of Physics and Astronomy, Iowa State University, Ames, IA.
Wang Y; Department of Physics and Astronomy, Iowa State University, Ames, IA.
Wang X; Department of Physics and Astronomy, Iowa State University, Ames, IA.; Molecular, Cellular, and Developmental Biology Interdepartmental Program, Iowa State University, Ames, IA.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Jul 05; Vol. 220 (7).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Actins/*genetics
DNA/*genetics
Deoxyribonucleases/*genetics
Cell Physiological Phenomena/genetics ; Deoxyribonuclease (Pyrimidine Dimer)/genetics ; Extracellular Matrix/genetics ; Humans ; Podosomes/genetics
Czasopismo naukowe
Tytuł :
The three Endonuclease III variants of Deinococcus radiodurans possess distinct and complementary DNA repair activities.
Autorzy :
Sarre A; The Norwegian Structural Biology Centre (NorStruct), Department of Chemistry, UiT the Arctic University of Norway, N-9037 Tromsø, Norway.
Stelter M; Univ. Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Rollo F; Instituto de Tecnologia Quimica e Biologica (ITQB), Universidade Nova de Lisboa, Av da Republica (EAN), 2780-157 Oeiras, Portugal.
De Bonis S; Univ. Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France.
Seck A; Univ. Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France; Univ. Grenoble Alpes, CEA, CNRS, INAC, SyMMES UMR 5819, Grenoble, France.
Hognon C; LPCT, UMR 7019, Université de Lorraine, CNRS, Vandoeuvre-les-Nancy, France.
Ravanat JL; Univ. Grenoble Alpes, CEA, CNRS, INAC, SyMMES UMR 5819, Grenoble, France.
Monari A; LPCT, UMR 7019, Université de Lorraine, CNRS, Vandoeuvre-les-Nancy, France.
Dehez F; LPCT, UMR 7019, Université de Lorraine, CNRS, Vandoeuvre-les-Nancy, France.
Moe E; The Norwegian Structural Biology Centre (NorStruct), Department of Chemistry, UiT the Arctic University of Norway, N-9037 Tromsø, Norway; Instituto de Tecnologia Quimica e Biologica (ITQB), Universidade Nova de Lisboa, Av da Republica (EAN), 2780-157 Oeiras, Portugal. Electronic address: .
Timmins J; Univ. Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2019 Jun; Vol. 78, pp. 45-59. Date of Electronic Publication: 2019 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Repair*
Mutation*
DNA, Complementary/*genetics
Deinococcus/*enzymology
Deinococcus/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*metabolism
Biocatalysis ; DNA, Complementary/metabolism ; Deoxyribonuclease (Pyrimidine Dimer)/chemistry ; Humans ; Molecular Dynamics Simulation ; Protein Conformation ; Pyrimidines/metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
The lyase activity of bifunctional DNA glycosylases and the 3'-diesterase activity of APE1 contribute to the repair of oxidized bases in nucleosomes.
Autorzy :
Maher RL; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405-0068, USA.
Wallace SS; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405-0068, USA.
Pederson DS; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405-0068, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2019 Apr 08; Vol. 47 (6), pp. 2922-2931.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA/*genetics
DNA-(Apurinic or Apyrimidinic Site) Lyase/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Nucleosomes/*enzymology
Chromatin/enzymology ; Chromatin/genetics ; DNA/chemistry ; DNA Damage/genetics ; DNA Glycosylases/chemistry ; DNA Glycosylases/genetics ; DNA Repair ; DNA-(Apurinic or Apyrimidinic Site) Lyase/chemistry ; Deoxyribonuclease (Pyrimidine Dimer)/chemistry ; Esterases/genetics ; Humans ; Lyases/chemistry ; Lyases/genetics ; Nucleosomes/genetics ; Oxidation-Reduction
Czasopismo naukowe

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