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Wyszukujesz frazę ""Dipeptides"" wg kryterium: Temat


Tytuł :
Design, synthesis and biological evaluation of dipeptides as novel non-covalent 20S proteasome inhibitors.
Autorzy :
Yang YJ; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Wang K; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Yang Y; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Lai FF; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Material Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Chen XG; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Material Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Xiao ZY; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
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Źródło :
Journal of Asian natural products research [J Asian Nat Prod Res] 2021 May; Vol. 23 (5), pp. 436-451. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Dipeptides*/pharmacology
Proteasome Inhibitors*/pharmacology
Molecular Structure ; Proteasome Endopeptidase Complex/metabolism
Czasopismo naukowe
Tytuł :
Translation of Mycobacterium Survival Strategy to Develop a Lipo-peptide based Fusion Inhibitor*.
Autorzy :
Sardar A; Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, PIN-741246, India.
Lahiri A; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, PIN-741246, India.
Kamble M; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, PIN-741246, India.
Mallick AI; Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, PIN-741246, India.
Tarafdar PK; Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, PIN-741246, India.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Mar 08; Vol. 60 (11), pp. 6101-6106. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
Dipeptides/*pharmacology
Lipopeptides/*pharmacology
Membrane Fusion/*drug effects
Virus Internalization/*drug effects
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/toxicity ; Dipeptides/chemistry ; Dipeptides/toxicity ; Dogs ; Humans ; Influenza A Virus, H1N1 Subtype/drug effects ; Lipopeptides/chemistry ; Lipopeptides/toxicity ; Liposomes/chemistry ; Madin Darby Canine Kidney Cells ; Murine hepatitis virus/drug effects ; Phosphatidylcholines/chemistry ; Phosphatidylethanolamines/chemistry ; Rats
Czasopismo naukowe
Tytuł :
Acute and long-term effects of saxagliptin on post-prandial glycemic response in obese patients with impaired glucose tolerance.
Autorzy :
Rezki A; Department of Endocrinology, Diabetology, Nutrition, Jean Verdier Hospital, AP-HP, CRNH-IdF, CINFO, Paris Nord University, Sorbonne Paris Cité, Bondy, France; Sorbonne Paris Cité, UMR U1153 Inserm/U1125 Inra/Cnam/Université Paris 13, Bobigny, France.
Fysekidis M; Department of Endocrinology, Diabetology, Nutrition, Jean Verdier Hospital, AP-HP, CRNH-IdF, CINFO, Paris Nord University, Sorbonne Paris Cité, Bondy, France; Sorbonne Paris Cité, UMR U1153 Inserm/U1125 Inra/Cnam/Université Paris 13, Bobigny, France.
Chiheb S; Department of Endocrinology, Diabetology, Nutrition, Jean Verdier Hospital, AP-HP, CRNH-IdF, CINFO, Paris Nord University, Sorbonne Paris Cité, Bondy, France.
Vicaut E; Clinical Research Unit, Lariboisière-St Louis, Fernand Widal Hospital, APHP, Paris, France.
Cosson E; Department of Endocrinology, Diabetology, Nutrition, Jean Verdier Hospital, AP-HP, CRNH-IdF, CINFO, Paris Nord University, Sorbonne Paris Cité, Bondy, France; Sorbonne Paris Cité, UMR U1153 Inserm/U1125 Inra/Cnam/Université Paris 13, Bobigny, France.
Valensi P; Department of Endocrinology, Diabetology, Nutrition, Jean Verdier Hospital, AP-HP, CRNH-IdF, CINFO, Paris Nord University, Sorbonne Paris Cité, Bondy, France. Electronic address: .
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 Apr 09; Vol. 31 (4), pp. 1257-1266. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Postprandial Period*
Adamantane/*analogs & derivatives
Blood Glucose/*drug effects
Diabetes Mellitus, Type 2/*prevention & control
Dipeptides/*therapeutic use
Dipeptidyl-Peptidase IV Inhibitors/*therapeutic use
Glucose Intolerance/*drug therapy
Obesity/*complications
Adamantane/adverse effects ; Adamantane/therapeutic use ; Adult ; Biomarkers/blood ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/etiology ; Dipeptides/adverse effects ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Double-Blind Method ; Female ; France ; Glucose Intolerance/blood ; Glucose Intolerance/diagnosis ; Glucose Intolerance/etiology ; Humans ; Male ; Middle Aged ; Obesity/diagnosis ; Pilot Projects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The Antiproliferative and Apoptotic Effect of a Novel Synthesized S -Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos.
Autorzy :
Malebari AM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Abd Alhameed R; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Almarhoon Z; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Farooq M; Bio-Products Research Chair, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Wadaan MAM; Bio-Products Research Chair, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Deanship of Postgraduate Studies and Scientific Research, Almaarefa University, Riyadh 11597, Saudi Arabia.
Sharma A; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.
de la Torre BG; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.
Albericio F; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.; CIBER-BBN (Networking Centre on Bioengineering, Biomaterials and Nanomedicine) and Department of Organic Chemistry, University of Barcelona, 08028 Barcelona, Spain.; Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.
El-Faham A; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Ibrahimia, Alexandria 12321, Egypt.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 22; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Dipeptides/*pharmacology
Triazines/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dipeptides/chemical synthesis ; Dipeptides/chemistry ; Drug Evaluation, Preclinical ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Triazines/chemical synthesis ; Triazines/chemistry ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
The role of histidine dipeptides on postmortem acidification of broiler muscles with different energy metabolism.
Autorzy :
Baldi G; Department of Agricultural and Food Sciences, Alma Mater Studiorum, University of Bologna, 47521 Cesena, Italy.
Soglia F; Department of Agricultural and Food Sciences, Alma Mater Studiorum, University of Bologna, 47521 Cesena, Italy.
Laghi L; Department of Agricultural and Food Sciences, Alma Mater Studiorum, University of Bologna, 47521 Cesena, Italy.
Meluzzi A; Department of Agricultural and Food Sciences, Alma Mater Studiorum, University of Bologna, 47521 Cesena, Italy.
Petracci M; Department of Agricultural and Food Sciences, Alma Mater Studiorum, University of Bologna, 47521 Cesena, Italy. Electronic address: .
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Źródło :
Poultry science [Poult Sci] 2021 Feb; Vol. 100 (2), pp. 1299-1307. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Dipeptides*/metabolism
Energy Metabolism*
Histidine*/metabolism
Muscle, Skeletal/*metabolism
Animals ; Chickens ; Female ; Glycolysis ; Hydrogen-Ion Concentration ; Meat/analysis ; Pectoralis Muscles/metabolism ; Postmortem Changes
Czasopismo naukowe
Tytuł :
Classifying the superfamily of small heat shock proteins by using g-gap dipeptide compositions.
Autorzy :
Feng P; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611730, China. Electronic address: .
Liu W; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611730, China.
Huang C; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611730, China.
Tang Z; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611730, China.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jan 15; Vol. 167, pp. 1575-1578. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
MeSH Terms :
Machine Learning*
Computational Biology/*methods
Dipeptides/*classification
Heat-Shock Proteins, Small/*classification
Amino Acid Sequence ; Animals ; Databases, Protein ; Dipeptides/chemistry ; Dipeptides/genetics ; Heat-Shock Proteins, Small/chemistry ; Heat-Shock Proteins, Small/genetics ; Humans ; Proteomics/methods ; Sequence Alignment
Czasopismo naukowe
Tytuł :
Efficacy and safety of saxagliptin for the treatment of type 2 diabetes mellitus.
Autorzy :
Orime K; Department of Endocrinology and Metabolism, Graduate School of Medicine, Yokohama-City University , Yokohama, Japan.
Terauchi Y; Department of Endocrinology and Metabolism, Graduate School of Medicine, Yokohama-City University , Yokohama, Japan.
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Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2020 Dec; Vol. 21 (17), pp. 2101-2114. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adamantane/*analogs & derivatives
Diabetes Mellitus, Type 2/*drug therapy
Dipeptides/*therapeutic use
Dipeptidyl-Peptidase IV Inhibitors/*therapeutic use
Hypoglycemic Agents/*therapeutic use
Adamantane/administration & dosage ; Adamantane/adverse effects ; Adamantane/therapeutic use ; Blood Glucose/analysis ; Diabetes Mellitus, Type 2/blood ; Dipeptides/administration & dosage ; Dipeptides/adverse effects ; Dipeptidyl-Peptidase IV Inhibitors/administration & dosage ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Heart Failure/chemically induced ; Humans ; Hypoglycemia/chemically induced ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/adverse effects ; Randomized Controlled Trials as Topic ; Sodium-Glucose Transporter 2 Inhibitors/administration & dosage ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The effects of active double-layered furcellaran/gelatin hydrolysate film system with Ala-Tyr peptide on fresh Atlantic mackerel stored at -18 °C.
Autorzy :
Jamróz E; Department of Chemistry, University of Agriculture, ul. Balicka 122, 30-149 Kraków, Poland. Electronic address: .
Kulawik P; Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture, ul. Balicka 122, 30-149 Kraków, Poland. Electronic address: .
Tkaczewska J; Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture, ul. Balicka 122, 30-149 Kraków, Poland. Electronic address: .
Guzik P; Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture, ul. Balicka 122, 30-149 Kraków, Poland. Electronic address: .
Zając M; Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture, ul. Balicka 122, 30-149 Kraków, Poland.
Juszczak L; Department of Dietetics and Food Science, Faculty of Science & Technology, Jan Dlugosz University in Częstochowa, ul. Armii Krajowej 13/15, 42-200 Częstochowa, Poland. Electronic address: .
Krzyściak P; Department of Mycology, Collegium Medicum, Jagiellonian University, ul. Czysta 18, 31-121 Kraków, Poland. Electronic address: paweł..
Turek K; Department of Animal Product Technology, Faculty of Food Technology, University of Agriculture, ul. Balicka 122, 30-149 Kraków, Poland. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Feb 15; Vol. 338, pp. 127867. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Alginates/*chemistry
Dipeptides/*chemistry
Food Storage/*methods
Gelatin/*chemistry
Perciformes/*metabolism
Plant Gums/*chemistry
Animals ; Antioxidants/chemistry ; Biogenic Amines/analysis ; Chromatography, High Pressure Liquid ; Cold Temperature ; Dipeptides/pharmacology ; Food Preservation/methods ; Peptides/chemistry ; Peptides/pharmacology ; Perciformes/microbiology ; Pseudomonas/drug effects ; Pseudomonas/isolation & purification ; Tensile Strength
Czasopismo naukowe
Tytuł :
Deciphering the structural preference encoded in amide-I vibrations of lysine dipeptide in gas phase and in aqueous solution.
Autorzy :
Cai K; College of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, Fujian Normal University, Fuzhou 350007, China; Key Laboratory of Green Energy and Environment Catalysis, Ningde Normal University, Fujian Province University, Ningde 352100, China; Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, Xiamen 361005, China. Electronic address: .
Zheng X; College of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, Fujian Normal University, Fuzhou 350007, China; Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, Xiamen 361005, China.
Hou Y; College of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, Fujian Normal University, Fuzhou 350007, China; Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, Xiamen 361005, China.
Chen F; Key Laboratory of Green Energy and Environment Catalysis, Ningde Normal University, Fujian Province University, Ningde 352100, China.
Yan G; Key Laboratory of Green Energy and Environment Catalysis, Ningde Normal University, Fujian Province University, Ningde 352100, China.
Zhuang D; College of Chemistry and Materials Science, Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, Fujian Normal University, Fuzhou 350007, China; Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, Xiamen 361005, China.
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Źródło :
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2021 Feb 15; Vol. 247, pp. 119066. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Amides*
Dipeptides*
Molecular Dynamics Simulation*
Lysine ; Vibration
Czasopismo naukowe
Tytuł :
Umami-enhancing effect of typical kokumi-active γ-glutamyl peptides evaluated via sensory analysis and molecular modeling approaches.
Autorzy :
Yang J; College of Food Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China; Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Huang Y; College of Food Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Cui C; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Dong H; College of Food Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China; Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Zeng X; College of Food Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China; Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China. Electronic address: .
Bai W; College of Food Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China; Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Feb 15; Vol. 338, pp. 128018. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Taste*/drug effects
Dipeptides/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Sodium Glutamate/*metabolism
Adult ; Amino Acids/chemistry ; Amino Acids/metabolism ; Dipeptides/chemistry ; Female ; Flavoring Agents/chemistry ; Flavoring Agents/pharmacology ; Humans ; Hydrogen Bonding ; Male ; Middle Aged ; Models, Molecular ; Molecular Docking Simulation ; Receptors, G-Protein-Coupled/chemistry ; Sodium Glutamate/chemistry ; Sodium Glutamate/pharmacology
Czasopismo naukowe
Tytuł :
Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor.
Autorzy :
Oozeki T; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Nakai T; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.; Faculty of Life Sciences, Hiroshima Institute of Technology, Hiroshima, Japan.
Kozakai K; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Okamoto K; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Kuroda S; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Kobayashi K; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Tanizawa K; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Okajima T; Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 10; Vol. 12 (1), pp. 933. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*metabolism
Coenzymes/*metabolism
Dipeptides/*metabolism
Flavoproteins/*metabolism
Indolequinones/*metabolism
Mixed Function Oxygenases/*metabolism
Paracoccus denitrificans/*enzymology
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Catalysis ; Coenzymes/chemistry ; Dipeptides/chemistry ; Flavin-Adenine Dinucleotide/chemistry ; Flavin-Adenine Dinucleotide/metabolism ; Flavoproteins/chemistry ; Indolequinones/chemistry ; Mixed Function Oxygenases/chemistry ; Paracoccus denitrificans/chemistry ; Paracoccus denitrificans/genetics ; Paracoccus denitrificans/metabolism ; Tryptophan/chemistry ; Tryptophan/metabolism
Czasopismo naukowe
Tytuł :
Effect of stevia aqueous extract on the antidiabetic activity of saxagliptin in diabetic rats.
Autorzy :
Abdel-Aal RA; Department of Pharmacology, Faculty of Medicine, Assiut University, Egypt. Electronic address: .
Abdel-Rahman MS; Department of Pharmacology, Faculty of Medicine, Assiut University, Egypt. Electronic address: .
Al Bayoumi S; Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Egypt. Electronic address: .
Ali LA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Assiut University, Egypt. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jan 30; Vol. 265, pp. 113188. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Adamantane/*analogs & derivatives
Diabetes Mellitus, Experimental/*drug therapy
Dipeptides/*pharmacology
Hypoglycemic Agents/*pharmacology
Plant Extracts/*pharmacology
Stevia/*chemistry
Adamantane/administration & dosage ; Adamantane/pharmacology ; Animals ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Blood Glucose/drug effects ; Diabetes Mellitus, Experimental/physiopathology ; Dipeptides/administration & dosage ; Herb-Drug Interactions ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/isolation & purification ; Hypolipidemic Agents/isolation & purification ; Hypolipidemic Agents/pharmacology ; Insulin Resistance ; Male ; Niacinamide ; Plant Extracts/administration & dosage ; Rats ; Rats, Wistar ; Streptozocin
Czasopismo naukowe
Tytuł :
Self-Assembled Peptide Nanofibers with Voltage-Regulated Inverse Photoconductance.
Autorzy :
Shi H; State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China.; Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Li M; Fujian Key Laboratory of Medical Instrumentation and Pharmaceutical Technology, Fuzhou 350108, China.; College of Mechanical Engineering and Automation, Fuzhou University, Fuzhou 350108, China.
Shi J; State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China.; Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhang D; Shenyang National Laboratory for Materials Science, Institute of Metal Research, Shenyang 110016, China.
Fan Z; Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, Shanghai 201804, China.; Institute for Advanced Study, Tongji University, Shanghai 200092, China.
Zhang M; Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
Liu L; State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China.; Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jan 13; Vol. 13 (1), pp. 1057-1064. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article
MeSH Terms :
Dipeptides/*chemistry
Nanofibers/*chemistry
Peptides, Cyclic/*chemistry
Computer Storage Devices ; Computers, Molecular ; Dipeptides/radiation effects ; Electric Conductivity ; Nanofibers/radiation effects ; Peptides, Cyclic/radiation effects
Czasopismo naukowe
Tytuł :
A novel dipeptide type inhibitor of the Wnt/β-catenin pathway suppresses proliferation of acute myelogenous leukemia cells.
Autorzy :
Wakabayashi R; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
Hattori Y; Center for Instrumental Analysis, Kyoto Pharmaceutical University, Kyoto, Japan. Electronic address: .
Hosogi S; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan. Electronic address: .
Toda Y; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
Takata K; Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Kyoto, Japan.
Ashihara E; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jan 08; Vol. 535, pp. 73-79. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dipeptides/*pharmacology
Leukemia, Myeloid, Acute/*metabolism
Leukemia, Myeloid, Acute/*pathology
Wnt Signaling Pathway/*drug effects
Antineoplastic Agents/analysis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dipeptides/chemistry ; Drug Design ; Drug Evaluation, Preclinical ; G1 Phase Cell Cycle Checkpoints/drug effects ; Gene Expression Regulation, Leukemic/drug effects ; Humans ; Idarubicin/pharmacology ; Luciferases/metabolism
Czasopismo naukowe
Tytuł :
Evidence of NAAG-family tripeptide NAAG 2 in the Drosophila nervous system.
Autorzy :
Kozik EM; Biology Department, Grinnell College, Grinnell, IA, USA.
Marzluff EM; Chemistry Department, Grinnell College, Grinnell, IA, USA.
Lindgren CA; Biology Department, Grinnell College, Grinnell, IA, USA.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 Jan; Vol. 156 (1), pp. 38-47. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Dipeptides*
Central Nervous System/*metabolism
Drosophila melanogaster/*metabolism
Neurons/*metabolism
Animals ; Neuromuscular Junction/metabolism
Czasopismo naukowe
Tytuł :
Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety.
Autorzy :
Küçükbay H; Department of Chemistry, Faculty of Arts and Sciences, İnönü University, Malatya, Turkey.
Gönül Z; Department of Chemistry, Faculty of Arts and Sciences, İnönü University, Malatya, Turkey.
Küçükbay FZ; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, İnönü University, Malatya, Turkey.
Angeli A; Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Università Degli Studi Di Firenze, Florence, Italy.
Bartolucci G; Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Università Degli Studi Di Firenze, Florence, Italy.
Supuran CT; Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche E Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Università Degli Studi Di Firenze, Florence, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1021-1026.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*pharmacology
Biphenyl Compounds/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Dipeptides/*pharmacology
Picrates/*antagonists & inhibitors
Quinolones/*pharmacology
Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Dipeptides/chemistry ; Dose-Response Relationship, Drug ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Molecular Structure ; Quinolones/chemical synthesis ; Quinolones/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
From Compassionate Use to Phase 3 Trial: The Impact of Germany's PSMA-617 Literature.
Autorzy :
Hope TA; Department of Radiology and Biomedical Imaging, University of California, San Francisco, and Department of Radiology, San Francisco VA Medical Center, San Francisco, California .
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2020 Dec; Vol. 61 (Suppl 2), pp. 255S-256S.
Typ publikacji :
Journal Article
MeSH Terms :
Clinical Trials, Phase III as Topic*
Compassionate Use Trials*
Dipeptides*
Heterocyclic Compounds, 1-Ring*
Germany ; Humans
Czasopismo naukowe
Tytuł :
Lu-EB-PSMA Radioligand Therapy with Escalating Doses in Patients with Metastatic Castration-Resistant Prostate Cancer.
Autorzy :
Zang J; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Liu Q; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Sui H; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Wang R; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Jacobson O; Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and.
Fan X; Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Zhu Z; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Chen X; Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and .
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2020 Dec; Vol. 61 (12), pp. 1772-1778. Date of Electronic Publication: 2020 May 01.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Radiation Dosage*
Dipeptides/*therapeutic use
Heterocyclic Compounds, 1-Ring/*therapeutic use
Prostatic Neoplasms, Castration-Resistant/*pathology
Prostatic Neoplasms, Castration-Resistant/*radiotherapy
Aged ; Dipeptides/adverse effects ; Heterocyclic Compounds, 1-Ring/adverse effects ; Humans ; Ligands ; Male ; Neoplasm Metastasis ; Radiotherapy Dosage ; Safety ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Enantioseparation of alanyl-phenylalanine analogs by capillary electrophoresis using negatively charged cyclodextrins as chiral selectors.
Autorzy :
Konjaria ML; Friedrich Schiller University Jena, Department of Pharmaceutical/Medicinal Chemistry, Philosophenweg 14, 07743 Jena, Germany.
Scriba GKE; Friedrich Schiller University Jena, Department of Pharmaceutical/Medicinal Chemistry, Philosophenweg 14, 07743 Jena, Germany. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2020 Nov 22; Vol. 1632, pp. 461585. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclodextrins/*chemistry
Dipeptides/*isolation & purification
Electrophoresis, Capillary/*methods
Dipeptides/chemistry ; Electrolytes/chemistry ; Hydrogen-Ion Concentration ; Kinetics ; Peptides/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Highly specific recognition of denatured collagen by fluorescent peptide probes with the repetitive Gly-Pro-Pro and Gly-Hyp-Hyp sequences.
Autorzy :
Wei W; State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China. .
Li D
Cai X
Liu Z
Bai Z
Xiao J
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Źródło :
Journal of materials chemistry. B [J Mater Chem B] 2020 Nov 18; Vol. 8 (44), pp. 10093-10100.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Denaturation*
Collagen/*metabolism
Dipeptides/*metabolism
Fluorescent Dyes/*metabolism
Oligopeptides/*metabolism
Peptide Fragments/*metabolism
Animals ; Collagen/chemistry ; Collagen/genetics ; Dipeptides/analysis ; Dipeptides/genetics ; Fluorescent Dyes/analysis ; Humans ; Neoplasms/genetics ; Neoplasms/metabolism ; Oligopeptides/analysis ; Oligopeptides/genetics ; Peptide Fragments/analysis ; Peptide Fragments/genetics ; Rats
Czasopismo naukowe

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