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Wyszukujesz frazę ""Disease Models, Animal"" wg kryterium: Temat


Tytuł:
Mouse genome rewriting and tailoring of three important disease loci.
Autorzy:
Zhang W; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Golynker I; Department of Microbiology, NYU Langone Health, New York, NY, USA.
Brosh R; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Fajardo A; Department of Microbiology, NYU Langone Health, New York, NY, USA.
Zhu Y; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Wudzinska AM; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Ordoñez R; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Ribeiro-Dos-Santos AM; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Carrau L; Department of Microbiology, NYU Langone Health, New York, NY, USA.
Damani-Yokota P; Department of Microbiology, NYU Langone Health, New York, NY, USA.
Yeung ST; Department of Microbiology, NYU Langone Health, New York, NY, USA.
Khairallah C; Department of Microbiology, NYU Langone Health, New York, NY, USA.
Vela Gartner A; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Chalhoub N; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Huang E; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Ashe HJ; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.
Khanna KM; Department of Microbiology, NYU Langone Health, New York, NY, USA.; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.
Maurano MT; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.; Department of Pathology, NYU Langone Health, New York, NY, USA.
Kim SY; Department of Pathology, NYU Langone Health, New York, NY, USA.
tenOever BR; Department of Microbiology, NYU Langone Health, New York, NY, USA.; Department of Medicine, NYU Langone Health, New York, NY, USA.
Boeke JD; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA. .; Department of Biomedical Engineering, NYU Tandon School of Engineering, Brooklyn, NY, USA. .
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Źródło:
Nature [Nature] 2023 Nov; Vol. 623 (7986), pp. 423-431. Date of Electronic Publication: 2023 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2*/genetics
Angiotensin-Converting Enzyme 2*/metabolism
COVID-19*/genetics
COVID-19*/virology
Disease Models, Animal*
Genetic Engineering*/methods
Genome*/genetics
Tumor Suppressor Protein p53*/genetics
Animals ; Humans ; Mice ; Alleles ; DNA/genetics ; Drug Resistance, Microbial/genetics ; Mouse Embryonic Stem Cells/metabolism ; SARS-CoV-2/metabolism ; Serine Endopeptidases/genetics
Czasopismo naukowe
Tytuł:
Transgenic ferret models define pulmonary ionocyte diversity and function.
Autorzy:
Yuan F; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Gasser GN; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Lemire E; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Montoro DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Jagadeesh K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Zhang Y; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Duan Y; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Ievlev V; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Wells KL; Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Rotti PG; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Shahin W; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Winter M; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Rosen BH; Division of Pulmonary, Critical Care, Occupational, and Sleep Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Evans I; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Cai Q; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Yu M; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Walsh SA; Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Acevedo MR; Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Pandya DN; Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Akurathi V; Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Dick DW; Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Wadas TJ; Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Joo NS; Cystic Fibrosis Research Laboratory, Department of Psychology, Stanford University, Stanford, CA, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Wine JJ; Cystic Fibrosis Research Laboratory, Department of Psychology, Stanford University, Stanford, CA, USA.
Birket S; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Fernandez CM; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Leung HM; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
Tearney GJ; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
Verkman AS; Department of Medicine, UCSF, San Francisco, CA, USA.; Department of Physiology, UCSF, San Francisco, CA, USA.
Haggie PM; Department of Medicine, UCSF, San Francisco, CA, USA.; Department of Physiology, UCSF, San Francisco, CA, USA.
Scott K; Office of Animal Resources, University of Iowa, Iowa City, IA, USA.
Bartels D; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Meyerholz DK; Department of Pathology, University of Iowa, Iowa City, IA, USA.
Rowe SM; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Liu X; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Yan Z; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Haber AL; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA. .
Sun X; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. .
Engelhardt JF; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. .
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Źródło:
Nature [Nature] 2023 Sep; Vol. 621 (7980), pp. 857-867. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/genetics
Cystic Fibrosis*/metabolism
Cystic Fibrosis*/pathology
Disease Models, Animal*
Ferrets*/genetics
Ferrets*/physiology
Lung*/cytology
Lung*/metabolism
Lung*/pathology
Transgenes*/genetics
Animals ; Humans ; Animals, Genetically Modified ; Cell Lineage ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Trachea/cytology
Czasopismo naukowe
Tytuł:
Animal models for musculoskeletal research.
Autorzy:
Plotkin LI; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Roudebush Veterans Administration Medical Center, Indiana Center for Musculoskeletal Health, Indianapolis, IN 46202, USA. Electronic address: .
Kalajzic I; Center for Regenerative Medicine and Skeletal Development, UConn Health, Farmington, CT 06032, USA. Electronic address: .
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Źródło:
Bone [Bone] 2023 Aug; Vol. 173, pp. 116813. Date of Electronic Publication: 2023 May 25.
Typ publikacji:
Editorial; Introductory Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Disease Models, Animal*
Animals
Czasopismo naukowe
Tytuł:
Hippocampal demyelination is associated with increased magnetic susceptibility in a mouse model of concussion.
Autorzy:
To XV; The Queensland Brain Institute, The University of Queensland, Australia.
Vegh V; The Centre for Advanced Imaging, The University of Queensland, Australia; The ARC Centre for Innovation in Biomedical Imaging Technology, Brisbane, Australia.
Owusu-Amoah N; The Queensland Brain Institute, The University of Queensland, Australia.
Cumming P; Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland; School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia.
Nasrallah FA; The Queensland Brain Institute, The University of Queensland, Australia; The Centre for Advanced Imaging, The University of Queensland, Australia. Electronic address: .
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Źródło:
Experimental neurology [Exp Neurol] 2023 Jul; Vol. 365, pp. 114406. Date of Electronic Publication: 2023 Apr 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Concussion*/pathology
Demyelinating Diseases*/pathology
Disease Models, Animal*
Hippocampus*/pathology
Magnetic Phenomena*
Animals ; Mice ; Cross-Sectional Studies ; Electroshock ; Spatial Learning ; White Matter/pathology ; Entorhinal Cortex/pathology ; Avoidance Learning ; Cues ; Photic Stimulation ; CA1 Region, Hippocampal/pathology ; Male ; Axons/pathology ; CA3 Region, Hippocampal/pathology
Czasopismo naukowe
Tytuł:
Acute stress induces long-term metabolic, functional, and structural remodeling of the heart.
Autorzy:
Yoganathan T; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France. .
Perez-Liva M; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Nuclear Physics Group and IPARCOS, Department of Structure of Matter, Thermal Physics and Electronics, CEI Moncloa, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Balvay D; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Université Paris Cité, Plateforme d'Imageries du Vivant, PARCC, F-75015, Paris, France.
Le Gall M; Université Paris Cité, P53 proteom'IC facility, Institut Cochin, INSERM, CNRS, F-75014, Paris, France.
Lallemand A; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.
Certain A; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.
Autret G; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Université Paris Cité, Plateforme d'Imageries du Vivant, PARCC, F-75015, Paris, France.
Mokrani Y; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.
Guillonneau F; Institut de Cancérologie de l'Ouest, CNRS UMR6075 INSERM U1307, 15 rue André Boquel, F-49055, Angers, France.
Bruce J; Université Paris Cité, P53 proteom'IC facility, Institut Cochin, INSERM, CNRS, F-75014, Paris, France.
Nguyen V; Sorbonne Université, Laboratoire d'Imagerie Biomédicale, Inserm, CNRS, F-75006, Paris, France.
Gencer U; Service de Radiologie, AP-HP, hôpital européen Georges Pompidou, F-75015, Paris, France.
Schmitt A; Université Paris Cité, Cochin Imaging, Electron microscopy, Institut Cochin, INSERM, CNRS, F-75014, Paris, France.
Lager F; Université Paris Cité, Plateforme d'Imageries du Vivant, Institut Cochin, Inserm-CNRS, F-75014, Paris, France.
Guilbert T; Université Paris Cité, Cochin Imaging Photonic, IMAG'IC, Institut Cochin, Inserm, CNRS, F-75014, Paris, France.
Bruneval P; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.
Vilar J; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.
Maissa N; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.
Mousseaux E; Service de Radiologie, AP-HP, hôpital européen Georges Pompidou, F-75015, Paris, France.
Viel T; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France.; Université Paris Cité, Plateforme d'Imageries du Vivant, PARCC, F-75015, Paris, France.
Renault G; Université Paris Cité, Plateforme d'Imageries du Vivant, Institut Cochin, Inserm-CNRS, F-75014, Paris, France.
Kachenoura N; Sorbonne Université, Laboratoire d'Imagerie Biomédicale, Inserm, CNRS, F-75006, Paris, France.
Tavitian B; Université Paris Cité, Inserm, PARCC, F-75015, Paris, France. .; Université Paris Cité, Plateforme d'Imageries du Vivant, PARCC, F-75015, Paris, France. .; Service de Radiologie, AP-HP, hôpital européen Georges Pompidou, F-75015, Paris, France. .
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Źródło:
Nature communications [Nat Commun] 2023 Jun 28; Vol. 14 (1), pp. 3835. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Takotsubo Cardiomyopathy*/metabolism
Takotsubo Cardiomyopathy*/pathology
Disease Models, Animal*
Heart*/physiopathology
Stress, Psychological*/complications
Humans ; Female ; Animals ; Rats ; Rats, Wistar ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Glucose-6-Phosphate/metabolism ; Glycolysis
Czasopismo naukowe
Tytuł:
Editorial: Unconventional animal models in infectious disease research, volume II.
Autorzy:
Younes S; Biomedical Research Center, Qatar University, Doha, Qatar.; Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha, Qatar.
Zein N; Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha, Qatar.
Abunasser S; Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha, Qatar.
Kamareddine L; Biomedical Research Center, Qatar University, Doha, Qatar.; Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha, Qatar.
Kirienko NV; Department of BioSciences, Rice University, Houston, TX, United States.
Nasrallah GK; Biomedical Research Center, Qatar University, Doha, Qatar.; Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha, Qatar.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Jun 14; Vol. 13, pp. 1225129. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023).
Typ publikacji:
Editorial; Introductory Journal Article
MeSH Terms:
Communicable Diseases*
Disease Models, Animal*
Animals
Czasopismo naukowe
Tytuł:
Disrupted Maturation of Prefrontal Layer 5 Neuronal Circuits in an Alzheimer's Mouse Model of Amyloid Deposition.
Autorzy:
Chen C; Department of Neurology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, 210008, China.; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Wei J; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Ma X; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Xia B; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Shakir N; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Zhang JK; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Zhang L; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Cui Y; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Ferguson D; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
Qiu S; Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA. .
Bai F; Department of Neurology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, 210008, China. .
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Źródło:
Neuroscience bulletin [Neurosci Bull] 2023 Jun; Vol. 39 (6), pp. 881-892. Date of Electronic Publication: 2022 Sep 24.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Alzheimer Disease*/pathology
Amyloid beta-Peptides*/metabolism
Disease Models, Animal*
Neural Pathways*
Neurons*/metabolism
Neurons*/pathology
Plaque, Amyloid*/metabolism
Plaque, Amyloid*/pathology
Prefrontal Cortex*/metabolism
Prefrontal Cortex*/pathology
Animals ; Mice ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Biotinylation ; Dendritic Spines/metabolism ; Dendritic Spines/pathology ; Mice, Transgenic ; Presenilin-1/genetics ; Presenilin-1/metabolism ; Receptors, AMPA/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Synapses/metabolism ; Synaptic Transmission ; Male ; Female
Czasopismo naukowe
Tytuł:
Establishment of a novel model of endometriosis-associated ovarian cancer by transplanting uterine tissue from Arid1a/Pten knockout mice.
Autorzy:
Ono M; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Miyamoto T; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan. .
Asaka R; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Uchikawa J; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Ando H; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Tanaka Y; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Shinagawa M; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Yokokawa Y; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Asaka S; Department of Laboratory Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.; Department of Diagnostic Pathology, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Wang TL; Department of Pathology, Johns Hopkins Medical Institutions, 1550 Orleans Street, CRB-2 Rm 306, Baltimore, MD, 21287, USA.
Shih IM; Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 1550 Orleans Street, CRB-2 Rm 305, Baltimore, MD, 21287, USA.
Shiozawa T; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 May 23; Vol. 13 (1), pp. 8348. Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Disease Models, Animal*
Endometriosis*
Ovarian Neoplasms*
Transplants*
Animals ; Female ; Humans ; Mice ; DNA-Binding Proteins ; Doxycycline ; Mice, Knockout ; PTEN Phosphohydrolase ; Transcription Factors ; Tumor Microenvironment ; Uterus
Czasopismo naukowe
Tytuł:
A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation.
Autorzy:
Mashima R; Department of Clinical Laboratory Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan. .
Ohira M; Department of Clinical Laboratory Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Okuyama T; Department of Clinical Laboratory Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.; Department of Pediatrics and Clinical Genomics, Faculty of Medicine, Saitama Medical University, Moroyama, Saitama, 350-0495, Japan.
Onodera M; Department of Human Genetics, National Research Institute for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Takada S; Department of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 May 15; Vol. 13 (1), pp. 7865. Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Iduronate Sulfatase*/genetics
Mucopolysaccharidosis II*/genetics
Disease Models, Animal*
Animals ; Humans ; Mice ; Biomarkers ; Heparitin Sulfate ; Iduronic Acid ; Mutation
Czasopismo naukowe
Tytuł:
Use of the waxworm Galleria mellonella larvae as an infection model to study Acinetobacter baumannii.
Autorzy:
Ten KE; School of Science, Monash University Malaysia, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Muzahid NH; School of Science, Monash University Malaysia, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Rahman S; School of Science, Monash University Malaysia, Bandar Sunway, Selangor Darul Ehsan, Malaysia.; Tropical Medicine and Biology Multidisciplinary Platform, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Tan HS; School of Science, Monash University Malaysia, Bandar Sunway, Selangor Darul Ehsan, Malaysia.; Tropical Medicine and Biology Multidisciplinary Platform, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
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Źródło:
PloS one [PLoS One] 2023 Apr 05; Vol. 18 (4), pp. e0283960. Date of Electronic Publication: 2023 Apr 05 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Acinetobacter baumannii*/pathogenicity
Disease Models, Animal*
Moths*/microbiology
Animals ; Humans ; Larva/microbiology ; Virulence
Czasopismo naukowe
Tytuł:
Deacetylase-dependent and -independent role of HDAC3 in cardiomyopathy.
Autorzy:
Ren J; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
Zeng Q; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
Wu H; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
Liu X; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
Guida MC; Development Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.
Huang W; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China.
Zhai Y; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
Li J; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
Ocorr K; Development Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.
Bodmer R; Development Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.
Tang M; Department of Biochemistry and Molecular Biology, College of Hengyang Medical, University of South China, Hengyang, China.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Mar; Vol. 238 (3), pp. 647-658. Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiomyopathies*/enzymology
Cardiomyopathies*/genetics
Cardiomyopathies*/metabolism
Cardiomyopathies*/physiopathology
Disease Models, Animal*
Drosophila melanogaster*/enzymology
Drosophila melanogaster*/genetics
Drosophila melanogaster*/metabolism
Drosophila Proteins*/deficiency
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Histone Deacetylases*/deficiency
Histone Deacetylases*/genetics
Histone Deacetylases*/metabolism
Animals ; Gene Knockdown Techniques ; Heart/physiology ; Histones/chemistry ; Histones/metabolism ; Myocardium/metabolism ; Triglycerides/metabolism ; Homeostasis
Czasopismo naukowe
Tytuł:
The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease.
Autorzy:
Groza T; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
Gomez FL; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
Mashhadi HH; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
Muñoz-Fuentes V; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
Gunes O; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
Wilson R; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
Cacheiro P; William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.
Frost A; Mary Lyon Centre at MRC Harwell, Harwell Campus OX11 7UE, UK.
Keskivali-Bond P; Mary Lyon Centre at MRC Harwell, Harwell Campus OX11 7UE, UK.
Vardal B; Mary Lyon Centre at MRC Harwell, Harwell Campus OX11 7UE, UK.
McCoy A; Mary Lyon Centre at MRC Harwell, Harwell Campus OX11 7UE, UK.
Cheng TK; Mary Lyon Centre at MRC Harwell, Harwell Campus OX11 7UE, UK.
Santos L; Research Data Team, The Turing Institute, 96 Euston Rd, London NW1 2DB, UK.
Wells S; Mary Lyon Centre at MRC Harwell, Harwell Campus OX11 7UE, UK.
Smedley D; William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.
Mallon AM; Research Data Team, The Turing Institute, 96 Euston Rd, London NW1 2DB, UK.
Parkinson H; European Bioinformatics Institute, European Molecular Biology Laboratory, Welcome Genome Campus, Hinxton CB10 1SD, UK.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2023 Jan 06; Vol. 51 (D1), pp. D1038-D1045.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Databases, Factual*
Mice, Knockout*
Disease Models, Animal*
Animals ; Humans ; Mice ; Phenotype
Czasopismo naukowe
Tytuł:
A Mouse Model of Multiple System Atrophy: Bench to Bedside.
Autorzy:
Stefanova N; Laboratory for Translational Neurodegeneration Research, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria. .
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Źródło:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2023 Jan; Vol. 20 (1), pp. 117-126. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Disease Models, Animal*
Multiple System Atrophy*/epidemiology
Multiple System Atrophy*/genetics
Multiple System Atrophy*/physiopathology
Multiple System Atrophy*/therapy
Translational Research, Biomedical*
Animals ; Humans ; Mice ; alpha-Synuclein/metabolism ; Brain/metabolism ; Brain/pathology ; Mice, Transgenic ; Neuropathology ; Oligodendroglia/metabolism ; Phenotype
Czasopismo naukowe
Tytuł:
Mice Are Not Small Furry People! A New Hirschsprung Disease Model Lets Us Pretend This Is Not True.
Autorzy:
Heuckeroth RO; The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Abramson Research Center, Philadelphia, Pennsylvania. Electronic address: .
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Źródło:
Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2023; Vol. 15 (6), pp. 1533-1534. Date of Electronic Publication: 2023 Mar 13.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Hirschsprung Disease*
Disease Models, Animal*
Animals ; Mice
Opinia redakcyjna
Tytuł:
Impactful in disease research: a DMM year in review.
Autorzy:
Hackett R; The Company of Biologists, Bidder Building, Station Road, Histon, Cambridge CB24 9LF, UK.
Patton EE; MRC Human Genetics Unit, and Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK.
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Źródło:
Disease models & mechanisms [Dis Model Mech] 2023 Jan 01; Vol. 16 (1). Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:
Editorial
MeSH Terms:
Disease Models, Animal*
Biomedical Research*
Animals
Opinia redakcyjna
Tytuł:
miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway.
Autorzy:
Yang Z; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.; School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Yang L; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Sun Z; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Rong Y; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Bai C; School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Dong Q; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.; School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Jian L; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
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Źródło:
Cancer biology & therapy [Cancer Biol Ther] 2023 Dec 31; Vol. 24 (1), pp. 2281459. Date of Electronic Publication: 2023 Nov 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioblastoma*/genetics
MicroRNAs*/genetics
Adult ; Humans ; Animals ; Mice ; Carcinogenesis ; Signal Transduction ; Cell Transformation, Neoplastic ; Disease Models, Animal ; Apolipoproteins
Czasopismo naukowe
Tytuł:
MiR-597-5p inhibits carcinogenesis and macrophage recruitment in colitis-related colorectal cancer via reducing the expression of CXCL5.
Autorzy:
Li S; Department of Hepatobiliary and Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Yu M; Department of Gastrointestinal Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Wang X; Medical Department, China-Japan Union Hospital of Jilin University, Changchun, China.
Fei B; Department of Gastrointestinal Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
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Źródło:
Cancer biology & therapy [Cancer Biol Ther] 2023 Dec 31; Vol. 24 (1), pp. 2274122. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Colitis*/chemically induced
Colitis*/complications
Colitis*/genetics
Colonic Neoplasms*/pathology
MicroRNAs*/genetics
Colorectal Neoplasms*/genetics
Mice ; Animals ; Carcinogenesis/genetics ; Macrophages/metabolism ; Dextran Sulfate/toxicity ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Quinoa protein and its hydrolysate ameliorated DSS-induced colitis in mice by modulating intestinal microbiota and inhibiting inflammatory response.
Autorzy:
Li Y; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
Zhang Y; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
Tuo Y; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
You H; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
Li J; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
Wang L; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
Liu X; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
Ding L; College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 8), pp. 127588. Date of Electronic Publication: 2023 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Chenopodium quinoa*
Gastrointestinal Microbiome*
Colitis*/chemically induced
Colitis*/drug therapy
Colitis*/metabolism
Colitis, Ulcerative*/metabolism
Animals ; Mice ; NF-KappaB Inhibitor alpha/metabolism ; NF-kappa B/metabolism ; Toll-Like Receptor 4/metabolism ; Colon ; Dextran Sulfate/adverse effects ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Porphyra haitanensis polysaccharide-functionalized selenium nanoparticles for effective alleviation of ulcerative colitis.
Autorzy:
Xu Y; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Wang XC; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Jiang W; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Chen LH; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Chen T; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Wu D; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Hu JN; SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 8), pp. 127570. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Colitis, Ulcerative*/chemically induced
Colitis, Ulcerative*/drug therapy
Colitis, Ulcerative*/pathology
Selenium*/pharmacology
Porphyra*
Colitis*
Nanoparticles*
Animals ; Mice ; Colon ; Polysaccharides/adverse effects ; Disease Models, Animal ; Dextran Sulfate/adverse effects ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Scytosiphon lomentaria fucoidan ameliorates DSS-induced colitis in dietary fiber-deficient mice via modulating the gut microbiota and inhibiting the TLR4/NF-κB/MLCK pathway.
Autorzy:
Jia J; School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, PR China.
Zheng W; School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, PR China.
Tang S; School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, PR China.
Song S; School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, PR China; National & Local Joint Engineering Laboratory for Marine Bioactive Polysaccharide Development and Application, Dalian Polytechnic University, Dalian 116034, PR China.
Ai C; School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, PR China; National & Local Joint Engineering Laboratory for Marine Bioactive Polysaccharide Development and Application, Dalian Polytechnic University, Dalian 116034, PR China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 8), pp. 127337. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*
Colitis*/chemically induced
Colitis*/drug therapy
Colitis, Ulcerative*
Humans ; Animals ; Mice ; NF-kappa B ; Toll-Like Receptor 4 ; Myosin-Light-Chain Kinase ; Polysaccharides/pharmacology ; Polysaccharides/therapeutic use ; Dietary Fiber/pharmacology ; Colon ; Dextran Sulfate ; Disease Models, Animal ; Mice, Inbred C57BL
Czasopismo naukowe

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