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Wyszukujesz frazę ""Disease Models, Animal"" wg kryterium: Temat


Tytuł :
An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities.
Autorzy :
Watamura N; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Sato K; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.; Laboratory for Molecular Brain Science, Department of Life Science and Medical Bioscience, Waseda University, Shinjuku, Tokyo 162-8480, Japan.
Shiihashi G; Neurological Institute, Shonan Keiiku Hospital, 4360 Endo, Fujisawa, Kanagawa 252-0816, Japan.
Iwasaki A; Yamaguchi University School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.
Kamano N; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Takahashi M; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Sekiguchi M; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Mihira N; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Fujioka R; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Nagata K; Department of Functional Anatomy and Neuroscience, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan.
Hashimoto S; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Saito T; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.; Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467-8601, Japan.
Ohshima T; Laboratory for Molecular Brain Science, Department of Life Science and Medical Bioscience, Waseda University, Shinjuku, Tokyo 162-8480, Japan.
Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Sasaguri H; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
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Źródło :
Science advances [Sci Adv] 2022 Jun 10; Vol. 8 (23), pp. eabm6155. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/genetics
Alzheimer Disease*/pathology
Disease Models, Animal*
Amyloid Precursor Protein Secretases/genetics ; Amyloid beta-Peptides/genetics ; Animals ; Gene Knock-In Techniques ; Humans ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Pathological Characteristics of Echovirus 30 Infection in a Mouse Model.
Autorzy :
Li J; Department of Medical Microbiology, Weifang Medical Universitygrid.268079.2, Weifang, People's Republic of China.; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhang G; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Sun Q; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhang K; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Lu H; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiao J; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Han Z; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhao H; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Xu W; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Zhang Y; WHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Biosafety, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Liu Z; Department of Medical Microbiology, Weifang Medical Universitygrid.268079.2, Weifang, People's Republic of China.
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Źródło :
Journal of virology [J Virol] 2022 May 11; Vol. 96 (9), pp. e0012922. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Echovirus Infections*/pathology
Glioma*
Animals ; Cell Line, Tumor ; Enterovirus B, Human/pathogenicity ; Humans ; Meningitis, Aseptic/pathology ; Meningitis, Aseptic/virology ; Mice ; Mice, Knockout ; Phylogeny ; RNA, Viral/genetics ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
C57BL/6J Mice Are Not Suitable for Modeling Severe SARS-CoV-2 Beta and Gamma Variant Infection.
Autorzy :
Currey JM; Tulane National Primate Research Center, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Rabito F; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Maness NJ; Tulane National Primate Research Center, Covington, LA 70433, USA.
Blair RV; Tulane National Primate Research Center, Covington, LA 70433, USA.
Rappaport J; Tulane National Primate Research Center, Covington, LA 70433, USA.
Qin X; Tulane National Primate Research Center, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Kolls JK; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Srivastava AK; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.
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Źródło :
Viruses [Viruses] 2022 May 05; Vol. 14 (5). Date of Electronic Publication: 2022 May 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/virology
Disease Models, Animal*
SARS-CoV-2*/genetics
Angiotensin-Converting Enzyme 2 ; Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Viral Proteins
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Tyrphostin A9 protects axons in experimental autoimmune encephalomyelitis through activation of ERKs.
Autorzy :
Dai X; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Wang Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Li Y; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, United States of America; Research Service, VA Portland Health Care System, Portland, OR 97239, United States of America.
Zhong Y; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, United States of America.
Pei M; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Long J; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Dong X; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Chen YL; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Wang Q; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Wang G; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China. Electronic address: .
Gold BG; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, United States of America.
Vandenbark AA; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, United States of America; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR 97239, United States of America; Research Service, VA Portland Health Care System, Portland, OR 97239, United States of America.
Neve KA; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR 97239, United States of America; Research Service, VA Portland Health Care System, Portland, OR 97239, United States of America.
Offner H; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, United States of America; Anesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR 97239, United States of America; Research Service, VA Portland Health Care System, Portland, OR 97239, United States of America.
Wang C; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200126, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, United States of America; Research Service, VA Portland Health Care System, Portland, OR 97239, United States of America. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2022 Apr 01; Vol. 294, pp. 120383. Date of Electronic Publication: 2022 Feb 07.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Axons/*drug effects
Encephalomyelitis, Autoimmune, Experimental/*prevention & control
Extracellular Signal-Regulated MAP Kinases/*metabolism
Gene Expression Regulation/*drug effects
Neuroblastoma/*drug therapy
Tyrphostins/*pharmacology
Animals ; Encephalomyelitis, Autoimmune, Experimental/etiology ; Encephalomyelitis, Autoimmune, Experimental/metabolism ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Extracellular Signal-Regulated MAP Kinases/genetics ; Female ; Humans ; Mice ; Mice, Inbred C57BL ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms.
Autorzy :
Bove M; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Schiavone S; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Tucci P; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Sikora V; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; Department of Pathology, Sumy State University, Sumy, Ukraine.
Dimonte S; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Colia AL; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Morgese MG; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Trabace L; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy. Electronic address: .
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Źródło :
Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2022 Jul 13; Vol. 117, pp. 110560. Date of Electronic Publication: 2022 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Autism Spectrum Disorder*/chemically induced
Autism Spectrum Disorder*/genetics
Disease Models, Animal*
Ketamine*/adverse effects
Animals ; Brain-Derived Neurotrophic Factor/metabolism ; Glutamates ; Mice ; gamma-Aminobutyric Acid
Czasopismo naukowe
Tytuł :
The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model.
Autorzy :
Cochin M; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Luciani L; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Touret F; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Driouich JS; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Petit PR; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Moureau G; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Baronti C; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Laprie C; Laboratoire Vet-Histo, Marseille, France.
Thirion L; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Maes P; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, Leuven, Belgium.
Boudewijns R; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
de Lamballerie X; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France.
Nougairède A; Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207), Marseille, France. .
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Źródło :
Communications biology [Commun Biol] 2022 Mar 10; Vol. 5 (1), pp. 225. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/blood
COVID-19*/immunology
COVID-19*/virology
Disease Models, Animal*
Mesocricetus*
SARS-CoV-2/*physiology
Animals ; Antibodies, Neutralizing/blood ; Cytokines/genetics ; Female ; Gastrointestinal Tract/virology ; Genome, Viral ; Lung/virology ; Nasal Lavage Fluid/virology ; SARS-CoV-2/genetics ; Virus Replication
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Optimized mouse model of embolic MCAO: From cerebral blood flow to neurological outcomes.
Autorzy :
Wang R; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, and Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China.
Wang H; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, and Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China.
Liu Y; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, and Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China.
Chen D; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, and Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China.
Wang Y; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, and Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China.
Rocha M; Pittsburgh Institute of Brain Disorders & Recovery and UPMC Stroke Institute, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jadhav AP; Pittsburgh Institute of Brain Disorders & Recovery and UPMC Stroke Institute, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Smith A; Geriatric Research, Education and Clinical Center, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Ye Q; Pittsburgh Institute of Brain Disorders & Recovery and UPMC Stroke Institute, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Gao Y; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, and Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China.
Zhang W; Pittsburgh Institute of Brain Disorders & Recovery and UPMC Stroke Institute, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
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Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2022 Mar; Vol. 42 (3), pp. 495-509. Date of Electronic Publication: 2020 Apr 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebrovascular Circulation*
Disease Models, Animal*
Infarction, Middle Cerebral Artery/*pathology
Animals ; Ischemic Stroke/pathology ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters.
Autorzy :
Halfmann PJ; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Iida S; Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Iwatsuki-Horimoto K; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Maemura T; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Kiso M; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Scheaffer SM; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Darling TL; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Joshi A; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Loeber S; Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Singh G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Foster SL; Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Ying B; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Case JB; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Chong Z; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Whitener B; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Moliva J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Floyd K; Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Ujie M; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Nakajima N; Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Ito M; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Wright R; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Uraki R; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.
Warang P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gagne M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Li R; Department of Animal Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA.
Sakai-Tagawa Y; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Liu Y; Department of Animal Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA.
Larson D; Department of Animal Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA.
Osorio JE; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.; Colombia/Wisconsin One-Health Consortium and One-Health Genomic Laboratory, Universidad Nacional de Colombia, Medellín, Colombia.
Hernandez-Ortiz JP; Colombia/Wisconsin One-Health Consortium and One-Health Genomic Laboratory, Universidad Nacional de Colombia, Medellín, Colombia.
Henry AR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ciuoderis K; Colombia/Wisconsin One-Health Consortium and One-Health Genomic Laboratory, Universidad Nacional de Colombia, Medellín, Colombia.
Florek KR; Wisconsin State Laboratory of Hygiene, Madison, WI, USA.
Patel M; Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Odle A; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Wong LR; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Bateman AC; Wisconsin State Laboratory of Hygiene, Madison, WI, USA.
Wang Z; Department of Animal Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA.
Edara VV; Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Chong Z; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Franks J; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Jeevan T; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Fabrizio T; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
DeBeauchamp J; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Kercher L; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Seiler P; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Gonzalez-Reiche AS; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sordillo EM; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Chang LA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
van Bakel H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sullivan NJ; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Thackray LB; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Ueki H; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.
Yamayoshi S; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.
Imai M; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.
Perlman S; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Webby RJ; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Seder RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Suthar MS; Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA.
García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Schotsaert M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Suzuki T; Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Boon ACM; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA. .; Department of Pathology & Immunology, Washington University School of Medicine, St Louis, MO, USA. .; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA. .
Diamond MS; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA. .; Department of Pathology & Immunology, Washington University School of Medicine, St Louis, MO, USA. .; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA. .; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, MO, USA. .
Kawaoka Y; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. .; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan. .; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan. .
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Corporate Authors :
Consortium Mount Sinai Pathogen Surveillance (PSP) study group
Źródło :
Nature [Nature] 2022 Mar; Vol. 603 (7902), pp. 687-692. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Models, Animal*
COVID-19/*pathology
COVID-19/*virology
SARS-CoV-2/*pathogenicity
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Cricetinae ; Female ; Humans ; Lung/pathology ; Lung/virology ; Male ; Mesocricetus ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Transgenic ; Viral Load
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Cannabinol modulates neuroprotection and intraocular pressure: A potential multi-target therapeutic intervention for glaucoma.
Autorzy :
Somvanshi RK; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Zou S; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Kadhim S; InMed Pharmaceuticals Inc., 310-815 West Hastings Street, Vancouver, BC, Canada.
Padania S; InMed Pharmaceuticals Inc., 310-815 West Hastings Street, Vancouver, BC, Canada.
Hsu E; InMed Pharmaceuticals Inc., 310-815 West Hastings Street, Vancouver, BC, Canada.
Kumar U; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Mar 01; Vol. 1868 (3), pp. 166325. Date of Electronic Publication: 2021 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Cannabinol/*pharmacology
Glaucoma/*drug therapy
Intraocular Pressure/*drug effects
Neuroprotective Agents/*pharmacology
Retinal Ganglion Cells/*drug effects
Trabecular Meshwork/*drug effects
Animals ; Glaucoma/metabolism ; Glaucoma/pathology ; Male ; Mice ; Rats ; Rats, Wistar ; Retinal Ganglion Cells/metabolism ; Retinal Ganglion Cells/pathology ; Trabecular Meshwork/metabolism ; Trabecular Meshwork/pathology ; Transforming Growth Factor beta2/metabolism
Czasopismo naukowe
Tytuł :
Prevotella copri ameliorates cholestasis and liver fibrosis in primary sclerosing cholangitis by enhancing the FXR signalling pathway.
Autorzy :
Jiang B; Center for Global Health, School of Public Health, Nanjing Medical, University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China.
Yuan G; Center for Global Health, School of Public Health, Nanjing Medical, University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China.
Wu J; Center for Global Health, School of Public Health, Nanjing Medical, University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China.
Wu Q; Center for Global Health, School of Public Health, Nanjing Medical, University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China.
Li L; Center for Global Health, School of Public Health, Nanjing Medical, University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China; Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China. Electronic address: .
Jiang P; Center for Global Health, School of Public Health, Nanjing Medical, University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China; Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Nanjing, Jiangsu 211166, PR China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Mar 01; Vol. 1868 (3), pp. 166320. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Gastrointestinal Microbiome*
Cholangitis, Sclerosing/*complications
Cholestasis/*prevention & control
Liver Cirrhosis/*prevention & control
Prevotella/*physiology
RNA-Binding Proteins/*metabolism
Animals ; Cholestasis/etiology ; Cholestasis/metabolism ; Cholestasis/pathology ; Liver Cirrhosis/etiology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Male ; Mice ; Mice, Inbred C57BL ; RNA-Binding Proteins/genetics ; Signal Transduction
SCR Organism :
Prevotella copri
Czasopismo naukowe
Tytuł :
The Swedish dilemma - the almost exclusive use of APPswe-based mouse models impedes adequate evaluation of alternative β-secretases.
Autorzy :
Armbrust F; Biochemical Institute, Unit for Degradomics of the Protease Web, University of Kiel, Kiel, Germany.
Bickenbach K; Biochemical Institute, Unit for Degradomics of the Protease Web, University of Kiel, Kiel, Germany.
Marengo L; Institute for Pathobiochemistry, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Pietrzik C; Institute for Pathobiochemistry, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. Electronic address: .
Becker-Pauly C; Biochemical Institute, Unit for Degradomics of the Protease Web, University of Kiel, Kiel, Germany. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2022 Mar; Vol. 1869 (3), pp. 119164. Date of Electronic Publication: 2021 Oct 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Models, Animal*
Alzheimer Disease/*enzymology
Alzheimer Disease/*pathology
Amyloid Precursor Protein Secretases/*metabolism
Amyloid beta-Protein Precursor/*genetics
Amyloid Precursor Protein Secretases/genetics ; Animals ; Humans ; Mice, Transgenic ; Sweden
Czasopismo naukowe
Tytuł :
Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models.
Autorzy :
Zhang J; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Sun B; Department of Pathology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310009, P.R. China.
Yang J; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Chen Z; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Li Z; Department of Internal Neurology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Zhang N; Department of Internal Neurology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Li H; Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Shen L; Department of Internal Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2022 Mar; Vol. 25 (3). Date of Electronic Publication: 2022 Jan 18.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Disease Models, Animal*
Parkinson Disease, Secondary/*metabolism
Parkinson Disease, Secondary/*physiopathology
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Avoidance Learning/physiology ; Blotting, Western ; Chronic Disease ; DNA-Binding Proteins/metabolism ; Dopaminergic Neurons/cytology ; Glial Fibrillary Acidic Protein/metabolism ; Humans ; Immunohistochemistry ; Mice, Inbred C57BL ; Motor Activity/physiology ; Nerve Tissue Proteins/metabolism ; Parkinson Disease, Secondary/chemically induced ; Rotenone ; Substantia Nigra/cytology ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
Rat Models of Human Diseases and Related Phenotypes: A Novel Inventory of Causative Genes.
Autorzy :
Szpirer C; Université Libre de Bruxelles, B-6041, Gosselies, Belgium. .; Avenue Jassogne, 27, B-1410, Waterloo, Belgium. .
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Źródło :
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2022 Mar; Vol. 33 (1), pp. 88-90. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Models, Animal*
Phenotype*
Animals ; Humans ; Rats
Czasopismo naukowe
Tytuł :
OA foundations - experimental models of osteoarthritis.
Autorzy :
Zaki S; Sydney School of Veterinary Science, Faculty of Science, University of Sydney, Australia; Raymond Purves Bone and Joint Research Laboratory, Australia. Electronic address: .
Blaker CL; Raymond Purves Bone and Joint Research Laboratory, Australia; Murray Maxwell Biomechanics Laboratory, The Kolling Institute, University of Sydney Faculty of Medicine and Health, At Royal North Shore Hospital, Australia. Electronic address: .
Little CB; Raymond Purves Bone and Joint Research Laboratory, Australia. Electronic address: .
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Źródło :
Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2022 Mar; Vol. 30 (3), pp. 357-380. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Biomedical Research*
Disease Models, Animal*
Research Design*
Osteoarthritis/*therapy
Animals ; Humans ; Phenotype
Czasopismo naukowe
Tytuł :
The Mutant Mouse Resource and Research Center (MMRRC): the NIH-supported National Public Repository and Distribution Archive of Mutant Mouse Models in the USA.
Autorzy :
Amos-Landgraf J; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
Franklin C; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
Godfrey V; Department of Genetics and Office of the Vice Chancellor for Research, Univeristy of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Grieder F; Division of Comparative Medicine, Office of Research Infrastructure Programs, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA.
Grimsrud K; Mouse Biology Program, University of California, Davis, CA, USA.
Korf I; Department of Molecular and Cellular Biology, College of Biological Sciences and Bioinformatics Core, Genome Center, University of California, Davis, CA, USA.
Lutz C; The Jackson Laboratory, Bar Harbor, ME, USA.
Magnuson T; Department of Genetics and Office of the Vice Chancellor for Research, Univeristy of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Mirochnitchenko O; Division of Comparative Medicine, Office of Research Infrastructure Programs, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA.
Patel S; Department of Molecular and Cellular Biology, College of Biological Sciences and Bioinformatics Core, Genome Center, University of California, Davis, CA, USA.
Reinholdt L; The Jackson Laboratory, Bar Harbor, ME, USA.
Lloyd KCK; Mouse Biology Program, University of California, Davis, CA, USA. .
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Źródło :
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2022 Mar; Vol. 33 (1), pp. 203-212. Date of Electronic Publication: 2021 Jul 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Biomedical Research*
Disease Models, Animal*
Mice*/genetics
National Institutes of Health (U.S.)*
Animals ; Humans ; Reproducibility of Results ; United States
Czasopismo naukowe
Tytuł :
Remdesivir Metabolite GS-441524 Effectively Inhibits SARS-CoV-2 Infection in Mouse Models.
Autorzy :
Li Y; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.; Medi-X, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Cao L; Centre for Infection and Immunity Studies, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong 518107, China.
Li G; Guangdong Province Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong 510663, China.
Cong F; Guangdong Province Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong 510663, China.
Li Y; Guangdong Province Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong 510663, China.
Sun J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510182, China.
Luo Y; Guangdong Province Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong 510663, China.
Chen G; Guangdong Province Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong 510663, China.
Li G; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Wang P; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Xing F; Centre for Infection and Immunity Studies, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong 518107, China.
Ji Y; Centre for Infection and Immunity Studies, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong 518107, China.
Zhao J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510182, China.
Zhang Y; Guangdong Province Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong 510663, China.
Guo D; Centre for Infection and Immunity Studies, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong 518107, China.
Zhang X; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.; Medi-X, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 2785-2793. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Adenosine/*analogs & derivatives
Antiviral Agents/*pharmacology
COVID-19/*drug therapy
Adenosine/chemistry ; Adenosine/metabolism ; Adenosine/pharmacology ; Animals ; Antiviral Agents/chemistry ; Antiviral Agents/metabolism ; COVID-19/metabolism ; COVID-19/pathology ; Cells, Cultured ; Chlorocebus aethiops ; Dose-Response Relationship, Drug ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Protocol for chronic hepatitis B virus infection mouse model development by patient-derived orthotopic xenografts.
Autorzy :
Nagornykh AM; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
Tyumentseva MA; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
Tyumentsev AI; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
Akimkin VG; Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow, Russia.
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Źródło :
PloS one [PLoS One] 2022 Feb 23; Vol. 17 (2), pp. e0264266. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Hepatitis C, Chronic/*pathology
Primary Cell Culture/*methods
Xenograft Model Antitumor Assays/*standards
Animals ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/virology ; Cells, Cultured ; Hepatitis C, Chronic/virology ; Humans ; Liver Neoplasms/pathology ; Liver Neoplasms/virology ; Mice ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
Comparison of Experimental Middle East Respiratory Syndrome Coronavirus Infection Acquired by Three Individual Routes of Infection in the Common Marmoset.
Autorzy :
Nelson M; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
O'Brien LM; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
Davies C; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
Keyser E; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
Butcher W; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
Smither SJ; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
Nunez A; Animal and Plant Health Agency, Weybridge, Addlestone, Surrey, United Kingdom.
Salguero FJ; Public Health Englandgrid.271308.f, Salisbury, United Kingdom.
Lever MS; CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
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Źródło :
Journal of virology [J Virol] 2022 Feb 23; Vol. 96 (4), pp. e0173921. Date of Electronic Publication: 2021 Dec 15.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
COVID-19/*metabolism
Middle East Respiratory Syndrome Coronavirus/*metabolism
SARS-CoV-2/*metabolism
Animals ; Callithrix ; Humans
Czasopismo naukowe
Tytuł :
Establishment and evaluation of a specific antibiotic-induced inflammatory bowel disease model in rats.
Autorzy :
Tong G; Departments of General Surgery, Huzhou Central Hospital, Huzhou, Zhejiang, China.; Central Laboratory, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Qian H; Departments of General Surgery, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Li D; Central Laboratory, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Li J; Central Laboratory, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Chen J; Central Laboratory, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Li X; Orthopedic Surgery, Huzhou Central Hospital, Huzhou, Zhejiang, China.
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Źródło :
PloS one [PLoS One] 2022 Feb 22; Vol. 17 (2), pp. e0264194. Date of Electronic Publication: 2022 Feb 22 (Print Publication: 2022).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Anti-Bacterial Agents/*toxicity
Inflammatory Bowel Diseases/*physiopathology
Animals ; C-Reactive Protein/metabolism ; Female ; Inflammatory Bowel Diseases/etiology ; Inflammatory Bowel Diseases/metabolism ; Interleukins/metabolism ; Rats ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe

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