Skocz do pozycji: 1.

Tytuł:

Transgenic marmosets mimic Parkinson's symptoms.

Autorzy:

Normile D

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Źródło:

Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1402. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Wiadomości

MeSH Terms:

Animals, Genetically Modified*
Callithrix*
Parkinson Disease*
Disease Models, Animal*
Animals ; Humans

Periodyk

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 2.

Tytuł:

Invited Perspective: Humanized Mice for Arsenic Metabolism-A Better Model for Investigating Arsenic-Induced Diseases?

Autorzy:

States JC; Department of Pharmacology and Toxicology, Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA.
Barchowsky A; Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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Źródło:

Environmental health perspectives [Environ Health Perspect] 2023 Dec; Vol. 131 (12), pp. 121308. Date of Electronic Publication: 2023 Dec 27.

Typ publikacji:

Journal Article

MeSH Terms:

Arsenic*/toxicity
Disease Models, Animal*
Animals ; Mice

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Establishment of a novel model of endometriosis-associated ovarian cancer by transplanting uterine tissue from Arid1a/Pten knockout mice.

Autorzy:

Ono M; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Miyamoto T; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan. .
Asaka R; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Uchikawa J; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Ando H; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Tanaka Y; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Shinagawa M; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Yokokawa Y; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Asaka S; Department of Laboratory Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.; Department of Diagnostic Pathology, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Wang TL; Department of Pathology, Johns Hopkins Medical Institutions, 1550 Orleans Street, CRB-2 Rm 306, Baltimore, MD, 21287, USA.
Shih IM; Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 1550 Orleans Street, CRB-2 Rm 305, Baltimore, MD, 21287, USA.
Shiozawa T; Department of Obstetrics and Gynecology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.

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Źródło:

Scientific reports [Sci Rep] 2023 May 23; Vol. 13 (1), pp. 8348. Date of Electronic Publication: 2023 May 23.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

MeSH Terms:

Disease Models, Animal*
Endometriosis*
Ovarian Neoplasms*
Transplants*
Animals ; Female ; Humans ; Mice ; DNA-Binding Proteins ; Doxycycline ; Mice, Knockout ; PTEN Phosphohydrolase ; Transcription Factors ; Tumor Microenvironment ; Uterus

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation.

Autorzy:

Mashima R; Department of Clinical Laboratory Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan. .
Ohira M; Department of Clinical Laboratory Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Okuyama T; Department of Clinical Laboratory Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.; Department of Pediatrics and Clinical Genomics, Faculty of Medicine, Saitama Medical University, Moroyama, Saitama, 350-0495, Japan.
Onodera M; Department of Human Genetics, National Research Institute for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Takada S; Department of Systems BioMedicine, National Research Institute for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.

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Źródło:

Scientific reports [Sci Rep] 2023 May 15; Vol. 13 (1), pp. 7865. Date of Electronic Publication: 2023 May 15.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Iduronate Sulfatase*/genetics
Mucopolysaccharidosis II*/genetics
Disease Models, Animal*
Animals ; Humans ; Mice ; Biomarkers ; Heparitin Sulfate ; Iduronic Acid ; Mutation

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

A murine model for the del(GJB6-D13S1830) deletion recapitulating the phenotype of human DFNB1 hearing impairment: generation and functional and histopathological study.

Autorzy:

Domínguez-Ruiz M; Servicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Murillo-Cuesta S; Institute for Biomedical Research 'Sols-Morreale', Spanish National Research Council-Autonomous University of Madrid, Madrid, Spain.; Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Contreras J; Institute for Biomedical Research 'Sols-Morreale', Spanish National Research Council-Autonomous University of Madrid, Madrid, Spain.; Anatomy and Embryology Department, Faculty of Veterinary, Universidad Complutense de Madrid, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Cantero M; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Garrido G; Servicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Martín-Bernardo B; Institute for Biomedical Research 'Sols-Morreale', Spanish National Research Council-Autonomous University of Madrid, Madrid, Spain.; Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Gómez-Rosas E; Servicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.
Fernández A; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Del Castillo FJ; Servicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Montoliu L; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Varela-Nieto I; Institute for Biomedical Research 'Sols-Morreale', Spanish National Research Council-Autonomous University of Madrid, Madrid, Spain.; Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain.
Del Castillo I; Servicio de Genética, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain. .; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER-ISCIII), Madrid, Spain. .

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Źródło:

BMC genomics [BMC Genomics] 2024 Apr 11; Vol. 25 (1), pp. 359. Date of Electronic Publication: 2024 Apr 11.

Typ publikacji:

Journal Article

MeSH Terms:

Connexins*/genetics
Hearing Loss*/genetics
Humans ; Animals ; Mice ; Disease Models, Animal ; Connexin 30/genetics ; Connexin 26/genetics ; Phenotype ; Mutation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

A modified rehabilitation paradigm bilaterally increased rat extensor digitorum communis muscle size but did not improve forelimb function after stroke.

Autorzy:

Caine S; College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada.
Alaverdashvili M; College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada.
Colbourne F; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Department of Psychology, University of Alberta, Edmonton, Canada.
Muir GD; Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.
Paterson PG; College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada.

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Źródło:

PloS one [PLoS One] 2024 Apr 11; Vol. 19 (4), pp. e0302008. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Stroke*
Stroke Rehabilitation*
Rats ; Male ; Animals ; Humans ; Rats, Sprague-Dawley ; Recovery of Function/physiology ; Forelimb ; Muscle, Skeletal ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 7.

Tytuł:

Reduced fetal cerebral blood flow predicts perinatal mortality in a mouse model of prenatal alcohol and cannabinoid exposure.

Autorzy:

Rouzer SK; Department of Neuroscience and Experimental Therapeutics, Texas A&M School of Medicine, 8447 Riverside Parkway, Bryan, TX, 77807, USA.
Sreeram A; Department of Neuroscience and Experimental Therapeutics, Texas A&M School of Medicine, 8447 Riverside Parkway, Bryan, TX, 77807, USA.
Miranda RC; Department of Neuroscience and Experimental Therapeutics, Texas A&M School of Medicine, 8447 Riverside Parkway, Bryan, TX, 77807, USA. .

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Źródło:

BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2024 Apr 11; Vol. 24 (1), pp. 263. Date of Electronic Publication: 2024 Apr 11.

Typ publikacji:

Journal Article

MeSH Terms:

Cannabinoids*/adverse effects
Perinatal Death*
Pregnancy ; Mice ; Female ; Animals ; Child ; Humans ; Perinatal Mortality ; Ethanol/adverse effects ; Fetus/blood supply ; Disease Models, Animal ; Cerebrovascular Circulation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 8.

Tytuł:

Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer's disease.

Autorzy:

Liu C; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Cárdenas-Rivera A; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Teitelbaum S; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Birmingham A; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Alfadhel M; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA.
Yaseen MA; Department of Bioengineering, Northeastern University, Boston, MA, 02115, USA. .

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Źródło:

Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Apr 10; Vol. 16 (1), pp. 78. Date of Electronic Publication: 2024 Apr 10.

Typ publikacji:

Journal Article

MeSH Terms:

Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Mice ; Animals ; Mice, Transgenic ; Neuroinflammatory Diseases ; Cerebrovascular Circulation/physiology ; Disease Models, Animal ; Oxygen

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 9.

Tytuł:

Intranasal administration of ceramide liposome suppresses allergic rhinitis by targeting CD300f in murine models.

Autorzy:

Ide T; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Izawa K; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. .
Diono W; Department of Materials Process Engineering, Nagoya University, Furo-Cho, Chikusa-Ku, Nagoya, 464-8603, Japan.
Kamei A; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Ando T; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Kaitani A; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Maehara A; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Yoshikawa A; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Yamamoto R; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Uchida S; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Gastroenterology Immunology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Wang H; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Kojima M; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Maeda K; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Immunological Diagnosis, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Nakano N; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Nakamura M; Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Shimizu T; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.; Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Ogawa H; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Okumura K; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Matsumoto F; Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Ikeda K; Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Goto M; Department of Materials Process Engineering, Nagoya University, Furo-Cho, Chikusa-Ku, Nagoya, 464-8603, Japan.
Kitaura J; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. .; Department of Science of Allergy and Inflammation, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan. .

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Źródło:

Scientific reports [Sci Rep] 2024 Apr 10; Vol. 14 (1), pp. 8398. Date of Electronic Publication: 2024 Apr 10.

Typ publikacji:

Journal Article

MeSH Terms:

Liposomes*
Rhinitis, Allergic*/drug therapy
Animals ; Mice ; Administration, Intranasal ; Sneezing ; Ceramides ; Disease Models, Animal ; Immunoglobulin E ; Nasal Mucosa ; Mice, Inbred BALB C ; Ovalbumin

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 10.

Tytuł:

Transcriptomic alterations in cortical astrocytes following the development of post-traumatic epilepsy.

Autorzy:

Leonard J; Department of Biomedical Sciences and Pathobiology, Faculty of Health Sciences, Virginia Tech, 970 Washington Street SW, Life Sciences I; Rm 249 (MC0910), Blacksburg, VA, 24061, USA.
Wei X; School of Neuroscience, Virginia Tech, Blacksburg, VA, 24061, USA.
Browning J; School of Neuroscience, Virginia Tech, Blacksburg, VA, 24061, USA.
Gudenschwager-Basso EK; Department of Biomedical Sciences and Pathobiology, Faculty of Health Sciences, Virginia Tech, 970 Washington Street SW, Life Sciences I; Rm 249 (MC0910), Blacksburg, VA, 24061, USA.
Li J; School of Neuroscience, Virginia Tech, Blacksburg, VA, 24061, USA.
Harris EA; Department of Biomedical Sciences and Pathobiology, Faculty of Health Sciences, Virginia Tech, 970 Washington Street SW, Life Sciences I; Rm 249 (MC0910), Blacksburg, VA, 24061, USA.
Olsen ML; School of Neuroscience, Virginia Tech, Blacksburg, VA, 24061, USA.
Theus MH; Department of Biomedical Sciences and Pathobiology, Faculty of Health Sciences, Virginia Tech, 970 Washington Street SW, Life Sciences I; Rm 249 (MC0910), Blacksburg, VA, 24061, USA. .

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Źródło:

Scientific reports [Sci Rep] 2024 Apr 10; Vol. 14 (1), pp. 8367. Date of Electronic Publication: 2024 Apr 10.

Typ publikacji:

Journal Article

MeSH Terms:

Epilepsy, Post-Traumatic*/etiology
Brain Injuries, Traumatic*/genetics
Brain Injuries, Traumatic*/metabolism
Humans ; Animals ; Astrocytes/metabolism ; Transcriptome ; Seizures ; Gene Expression Profiling ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 11.

Tytuł:

Intra-articular injection of miRNA-1 agomir, a novel chemically modified miRNA agonists alleviates osteoarthritis (OA) progression by downregulating Indian hedgehog in rats.

Autorzy:

Li P; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .
Gao Y; Department of Orthopaedic Surgery, Jincheng People's Hospital, Jincheng, 048000, Shanxi, China.
Zhou R; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Che X; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Wang H; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Cong L; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Jiang P; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Liang D; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Li P; Shanxi Province Fenyang Hospital, Fenyang, 032200, Shanxi, China.
Wang C; Department of Experimental Animal Center, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Li W; Department of Stomatology, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Sang S; Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education and College of Information and Computer, Taiyuan University of Technology, Jinzhong, 030600, China.
Duan Q; Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education and College of Information and Computer, Taiyuan University of Technology, Jinzhong, 030600, China.
Wei X; Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.

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Źródło:

Scientific reports [Sci Rep] 2024 Apr 06; Vol. 14 (1), pp. 8101. Date of Electronic Publication: 2024 Apr 06.

Typ publikacji:

Journal Article

MeSH Terms:

MicroRNAs*/genetics
MicroRNAs*/therapeutic use
Osteoarthritis*/drug therapy
Osteoarthritis*/genetics
Cartilage, Articular*
Rats ; Male ; Animals ; Hedgehog Proteins ; Rats, Sprague-Dawley ; Matrix Metalloproteinase 13/genetics ; Chondrocytes ; Injections, Intra-Articular ; Inflammation ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

Reversing valproic acid-induced autism-like behaviors through a combination of low-frequency repeated transcranial magnetic stimulation and superparamagnetic iron oxide nanoparticles.

Autorzy:

Afshari M; Department of Cognitive Psychology, Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran.
Gharibzadeh S; Department of Cognitive Psychology, Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran. s_.
Pouretemad H; Department of Cognitive Psychology, Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran.
Roghani M; Neurophysiology Research Center, Shahed University, Tehran, Iran. .

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Źródło:

Scientific reports [Sci Rep] 2024 Apr 06; Vol. 14 (1), pp. 8082. Date of Electronic Publication: 2024 Apr 06.

Typ publikacji:

Journal Article

MeSH Terms:

Autistic Disorder*/therapy
Autistic Disorder*/drug therapy
Autism Spectrum Disorder*/therapy
Autism Spectrum Disorder*/drug therapy
Prenatal Exposure Delayed Effects*/therapy
Prenatal Exposure Delayed Effects*/drug therapy
Pregnancy ; Female ; Rats ; Animals ; Humans ; Valproic Acid/pharmacology ; Transcranial Magnetic Stimulation ; Social Behavior ; Magnetic Iron Oxide Nanoparticles ; Disease Models, Animal ; Behavior, Animal/physiology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma.

Autorzy:

Waern I; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Akula S; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Allam VSRR; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Taha S; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Feyerabend TB; Division for Cellular Immunology, German Cancer Research Center, Heidelberg, Germany.
Åbrink M; Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Wernersson S; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.

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Źródło:

PloS one [PLoS One] 2024 Apr 05; Vol. 19 (4), pp. e0300668. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Asthma*
Mast Cells*/metabolism
Animals ; Mice ; Allergens/metabolism ; Bronchoalveolar Lavage Fluid ; Carboxypeptidases/metabolism ; Disease Models, Animal ; Inflammation/genetics ; Inflammation/metabolism ; Lung/metabolism ; Mice, Inbred BALB C ; Ovalbumin/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 14.

Tytuł:

Proteomic analysis of DEN and CCl 4 -induced hepatocellular carcinoma mouse model.

Autorzy:

Zhang Q; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Liu Y; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Ren L; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Li J; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.; School of Basic Medical Science, Anhui Medical University, Hefei, 230032, China.
Lin W; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Lou L; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Wang M; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Li C; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China.
Jiang Y; State Key Laboratory of Medicle Proteomics, Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing, 102206, China. .; School of Basic Medical Science, Anhui Medical University, Hefei, 230032, China. .

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Źródło:

Scientific reports [Sci Rep] 2024 Apr 05; Vol. 14 (1), pp. 8013. Date of Electronic Publication: 2024 Apr 05.

Typ publikacji:

Journal Article

MeSH Terms:

Carcinoma, Hepatocellular*/chemically induced
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/chemically induced
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Liver Neoplasms, Experimental*/chemically induced
Liver Neoplasms, Experimental*/genetics
Liver Neoplasms, Experimental*/metabolism
Mice ; Animals ; Humans ; Proteomics ; Diethylnitrosamine/adverse effects ; Liver Cirrhosis/pathology ; Disease Models, Animal ; Fatty Acid-Binding Proteins

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 15.

Tytuł:

Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models.

Autorzy:

Basheer N; Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, 845 10, Bratislava, Slovakia.
Buee L; Inserm, CHU Lille, CNRS, LilNCog - Lille Neuroscience & Cognition, University of Lille, 59000, Lille, France. .
Brion JP; Faculty of Medicine, Laboratory of Histology, Alzheimer and Other Tauopathies Research Group (CP 620), ULB Neuroscience Institute (UNI), Université Libre de Bruxelles, 808, Route de Lennik, 1070, Brussels, Belgium.
Smolek T; Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, 845 10, Bratislava, Slovakia.
Muhammadi MK; Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, 845 10, Bratislava, Slovakia.
Hritz J; CEITEC Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.; Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, 62500, Brno, Czech Republic.
Hromadka T; Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, 845 10, Bratislava, Slovakia.
Dewachter I; Biomedical Research Institute, BIOMED, Hasselt University, 3500, Hasselt, Belgium.
Wegmann S; German Center for Neurodegenerative Diseases, Charitéplatz 1, 10117, Berlin, Germany.; Einstein Center for Neurosciences Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Landrieu I; CNRS EMR9002 - BSI - Integrative Structural Biology, 59000, Lille, France.; Inserm, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Risk Factors and Molecular Determinants of Aging-Related Diseases, University of Lille, 59000, Lille, France.
Novak P; Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, 845 10, Bratislava, Slovakia.
Mudher A; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK.
Zilka N; Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska Cesta 9, 845 10, Bratislava, Slovakia. .; AXON Neuroscience R&D Services SE, Dubravska Cesta 9, 845 10, Bratislava, Slovakia. .

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Źródło:

Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Apr 04; Vol. 12 (1), pp. 52. Date of Electronic Publication: 2024 Apr 04.

Typ publikacji:

Systematic Review; Journal Article; Review

MeSH Terms:

Alzheimer Disease*/pathology
Tauopathies*/pathology
Animals ; Neurofibrillary Tangles/pathology ; Disease Models, Animal ; tau Proteins/metabolism ; Brain/pathology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 16.

Tytuł:

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis.

Autorzy:

Terron HM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.
Parikh SJ; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.
Abdul-Hay SO; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Sahara T; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Kang D; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Dickson DW; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
Saftig P; Institut für Biochemie, Christian-Albrechts-Universität zu Kiel, D-24098, Kiel, Germany.
LaFerla FM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, 92697, USA.
Lane S; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA.
Leissring MA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine (UCI MIND), Irvine, CA, 92697, USA. .; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA. .

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Źródło:

Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Apr 04; Vol. 16 (1), pp. 70. Date of Electronic Publication: 2024 Apr 04.

Typ publikacji:

Journal Article

MeSH Terms:

Alzheimer Disease*/pathology
Tauopathies*/genetics
Tauopathies*/metabolism
Aged ; Animals ; Humans ; Mice ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Cathepsin D ; Disease Models, Animal ; Mice, Knockout ; Mice, Transgenic ; tau Proteins/genetics ; tau Proteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 17.

Tytuł:

Microdose lithium improves behavioral deficits and modulates molecular mechanisms of memory formation in female SAMP-8, a mouse model of accelerated aging.

Autorzy:

Pereira AAR; Department of Pharmacology, Institute of Biomedical Sciences, Graduate Course on Pharmacology, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Pinto AM; Graduate Course on Gerontology, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Malerba HN; Department of Pharmacology, Institute of Biomedical Sciences, Graduate Course on Pharmacology, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Toricelli M; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Buck HS; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.; Department of Physiology, University of Mogi das Cruzes, Mogi das Cruzes, Sao Paulo, Brazil.
Viel TA; Department of Pharmacology, Institute of Biomedical Sciences, Graduate Course on Pharmacology, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.; Graduate Course on Gerontology, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.

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Źródło:

PloS one [PLoS One] 2024 Apr 04; Vol. 19 (4), pp. e0299534. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Lithium*/pharmacology
Lithium*/therapeutic use
Alzheimer Disease*/pathology
Phenylmercury Compounds*
Mice ; Female ; Animals ; Plaque, Amyloid/pathology ; Glycogen Synthase Kinase 3 beta ; Aging/metabolism ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 18.

Tytuł:

Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH.

Autorzy:

Stauffer WT; Department of Immunology & Microbiology, Scripps Research, La Jolla, California, United States of America.
Bobardt M; Department of Immunology & Microbiology, Scripps Research, La Jolla, California, United States of America.
Ure DR; Hepion Pharmaceuticals, Edison, New Jersey, United States of America.
Foster RT; Hepion Pharmaceuticals, Edison, New Jersey, United States of America.
Gallay P; Department of Immunology & Microbiology, Scripps Research, La Jolla, California, United States of America.

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Źródło:

PloS one [PLoS One] 2024 Apr 04; Vol. 19 (4), pp. e0301711. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/prevention & control
Carcinoma, Hepatocellular*/pathology
Diabetes Mellitus*/pathology
Liver Neoplasms*/genetics
Liver Neoplasms*/prevention & control
Liver Neoplasms*/drug therapy
Non-alcoholic Fatty Liver Disease*/pathology
Animals ; Humans ; Mice ; Cyclophilins/genetics ; Diet, High-Fat ; Disease Models, Animal ; Liver/pathology ; Mice, Inbred C57BL ; Peptidyl-Prolyl Isomerase F ; Streptozocin

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 19.

Tytuł:

Cranial irradiation disrupts homeostatic microglial dynamic behavior.

Autorzy:

Strohm AO; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Johnston C; Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Hernady E; Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Marples B; Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
O'Banion MK; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.; Del Monte Institute for Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Majewska AK; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA. ania_.; Del Monte Institute for Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA. ania_.; Center for Visual Science, University of Rochester Medical Center, Rochester, NY, 14642, USA. ania_.

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Źródło:

Journal of neuroinflammation [J Neuroinflammation] 2024 Apr 03; Vol. 21 (1), pp. 82. Date of Electronic Publication: 2024 Apr 03.

Typ publikacji:

Journal Article

MeSH Terms:

Microglia*/radiation effects
Brain*
Mice ; Animals ; Mice, Transgenic ; Disease Models, Animal ; Cranial Irradiation/adverse effects

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

Efficacy and safety of mesenchymal stem cell therapy for ovarian ageing in a mouse model.

Autorzy:

Pei W; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Fu L; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Guo W; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Wang Y; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Fan Y; Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Yang R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Li R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Qiao J; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China. .; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China. .
Yu Y; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China. .; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China. .; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China. .

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Źródło:

Stem cell research & therapy [Stem Cell Res Ther] 2024 Apr 03; Vol. 15 (1), pp. 96. Date of Electronic Publication: 2024 Apr 03.

Typ publikacji:

Journal Article

MeSH Terms:

Mesenchymal Stem Cell Transplantation*
Mesenchymal Stem Cells*/metabolism
Mice ; Animals ; Female ; Ovary/metabolism ; Tissue Distribution ; Cell Proliferation ; Disease Models, Animal ; Umbilical Cord

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 21.

Tytuł:

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.

Autorzy:

Yabo YA; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.
Moreno-Sanchez PM; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.
Pires-Afonso Y; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.; Neuro-Immunology Group, Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg.
Kaoma T; Bioinformatics Platform, Department of Medical Informatics, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.
Nosirov B; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.; Multiomics Data Science, Department of Cancer Research, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.
Scafidi A; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.; Neuro-Immunology Group, Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg.
Ermini L; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.
Lipsa A; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.
Oudin A; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.
Kyriakis D; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4362, Esch-sur-Alzette, Luxembourg.
Grzyb K; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4362, Esch-sur-Alzette, Luxembourg.
Poovathingal SK; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4362, Esch-sur-Alzette, Luxembourg.; Single Cell Analytics & Microfluidics Core, Vlaams Instituut Voor Biotechnologie-KU Leuven, 3000, Louvain, Belgium.
Poli A; Neuro-Immunology Group, Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg.
Muller A; Bioinformatics Platform, Department of Medical Informatics, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.
Toth R; Bioinformatics Platform, Department of Medical Informatics, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.; Multiomics Data Science, Department of Cancer Research, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.
Klink B; National Center of Genetics, Laboratoire National de Santé, L-3555, Dudelange, Luxembourg.; Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg.; German Cancer Consortium (DKTK): Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT/UCC), Cancer Consortium (DKTK) Partner Site Dresden, and German Cancer Research Center (DKFZ), Dresden, Heidelberg, 01307, Germany.; Institute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, 01307, Dresden, Germany.
Berchem G; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.; Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg.; Centre Hospitalier Luxembourg, L-1210, Luxembourg, Luxembourg.
Berthold C; Centre Hospitalier Luxembourg, L-1210, Luxembourg, Luxembourg.
Hertel F; Centre Hospitalier Luxembourg, L-1210, Luxembourg, Luxembourg.
Mittelbronn M; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4362, Esch-sur-Alzette, Luxembourg.; Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg.; Luxembourg Center of Neuropathology (LCNP), L-3555, Dudelange, Luxembourg.; National Center of Pathology (NCP), Laboratoire National de Santé, L-3555, Dudelange, Luxembourg.
Heiland DH; Translational Neurosurgery, Friedrich-Alexander University Erlangen Nuremberg, 91054, Erlangen, Germany.; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nuremberg, 91054, Erlangen, Germany.; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Neurosurgery, Medical Center, University of Freiburg, 79106, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, 79106, Freiburg, Germany.
Skupin A; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4362, Esch-sur-Alzette, Luxembourg.; Department of Physics and Material Science, University Luxembourg, L-4367, Belvaux, Luxembourg.; Department of Neuroscience, University of California San Diego, La Jolla, CA, 92093, USA.
Nazarov PV; Bioinformatics Platform, Department of Medical Informatics, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.; Multiomics Data Science, Department of Cancer Research, Luxembourg Institute of Health, L-1445, Strassen, Luxembourg.
Niclou SP; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.
Michelucci A; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg. .; Neuro-Immunology Group, Department of Cancer Research, Luxembourg Institute of Health, L-1210, Luxembourg, Luxembourg. .; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4362, Esch-sur-Alzette, Luxembourg. .
Golebiewska A; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg. .

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Źródło:

Genome medicine [Genome Med] 2024 Apr 02; Vol. 16 (1), pp. 51. Date of Electronic Publication: 2024 Apr 02.

Typ publikacji:

Journal Article

MeSH Terms:

Glioblastoma*/genetics
Glioblastoma*/metabolism
Brain Neoplasms*/genetics
Brain Neoplasms*/metabolism
Mice ; Animals ; Humans ; Microglia/metabolism ; Ecosystem ; Heterografts ; Phenotype ; Disease Models, Animal ; Dendritic Cells/metabolism ; Tumor Microenvironment/genetics

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 22.

Tytuł:

Double-negative T cells ameliorate psoriasis by selectively inhibiting IL-17A-producing γδ T cells.

Autorzy:

Wei Y; Immunology Research Center for Oral and Systemic Health, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Sun G; Immunology Research Center for Oral and Systemic Health, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Yang Y; Immunology Research Center for Oral and Systemic Health, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Li M; Immunology Research Center for Oral and Systemic Health, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Zheng S; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Wang X; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Zhong X; Immunology Research Center for Oral and Systemic Health, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Zhang Z; Immunology Research Center for Oral and Systemic Health, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Han X; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Cheng H; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Zhang D; Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. .; Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. .; Beijing Laboratory of Oral Health, Capital Medical University School of Basic Medicine, Beijing, 100069, China. .
Mei X; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. .

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Źródło:

Journal of translational medicine [J Transl Med] 2024 Apr 02; Vol. 22 (1), pp. 328. Date of Electronic Publication: 2024 Apr 02.

Typ publikacji:

Journal Article

MeSH Terms:

Interleukin-17*/metabolism
Psoriasis*/therapy
Humans ; Mice ; Animals ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Skin/pathology ; Imiquimod/adverse effects ; Imiquimod/metabolism ; Inflammation/pathology ; T-Lymphocytes/metabolism ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 23.

Tytuł:

Focused ultrasound-mediated blood-brain barrier opening is safe and feasible with moderately hypofractionated radiotherapy for brainstem diffuse midline glioma.

Autorzy:

Tazhibi M; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA.
McQuillan N; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA.
Wei HJ; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA.
Gallitto M; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA.
Bendau E; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Webster Carrion A; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Berg X; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA.
Kokossis D; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA.
Zhang X; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.; Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Zhang Z; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.; Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Jan CI; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA.; Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, 813, Taiwan.
Mintz A; Department of Radiology, Columbia University, New York, NY, 10027, USA.
Gartrell RD; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.; Division of Pediatric Oncology, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
Syed HR; Department of Neurosurgery, Children's National Hospital, Washington, DC, USA.; George Washington University, Washington, DC, USA.
Fonseca A; George Washington University, Washington, DC, USA.; Center for Cancer and Blood Disorders, Children's National Hospital, Washington, DC, USA.; The Brain Tumor Institute, Children's National Hospital, Washington, DC, USA.
Pavisic J; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.
Szalontay L; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.
Konofagou EE; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Zacharoulis S; Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Irving Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA. .; Bristol Myers Squibb, Princeton, NJ, 08901, USA. .
Wu CC; Department of Radiation Oncology, Columbia University Irving Medical Center, 622 W. 168th Street, New York, NY, 10032, USA. .; Herbert Irving Comprehensive Cancer Center, New York, NY, 10032, USA. .

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Źródło:

Journal of translational medicine [J Transl Med] 2024 Mar 30; Vol. 22 (1), pp. 320. Date of Electronic Publication: 2024 Mar 30.

Typ publikacji:

Journal Article

MeSH Terms:

Blood-Brain Barrier*
Glioma*/radiotherapy
Humans ; Rats ; Child ; Male ; Mice ; Animals ; Disease Models, Animal ; Rats, Sprague-Dawley ; Brain Stem ; Drug Delivery Systems/methods ; Magnetic Resonance Imaging ; Microbubbles ; Brain

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson's disease.

Autorzy:

Dong H; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Zhang X; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Duan Y; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
He Y; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Zhao J; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Wang Z; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Wang J; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Li Q; School of Life Science and Technology, Tongji University, 1239 Shipping Road, Shanghai, 200092, China.
Fan G; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Liu Z; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Shen C; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Zhang Y; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Yu M; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China. .
Fei J; School of Life Science and Technology, Tongji University, 1239 Shipping Road, Shanghai, 200092, China. .; Shanghai Engineering Research Center for Model Organisms, Shanghai Model Organisms Center, INC., Shanghai, 201203, China. .
Huang F; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China. .

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Źródło:

Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 30; Vol. 21 (1), pp. 80. Date of Electronic Publication: 2024 Mar 30.

Typ publikacji:

Journal Article

MeSH Terms:

Microglia*/metabolism
Parkinson Disease*/pathology
Animals ; Mice ; Disease Models, Animal ; Dopaminergic Neurons ; Hypoxia/metabolism ; Lipopolysaccharides/toxicity ; Mice, Inbred C57BL ; Neuroinflammatory Diseases ; Trained Immunity

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 25.

Tytuł:

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model.

Autorzy:

Tan B; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Zhang X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Ansari A; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Jadhav P; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Tan H; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Li K; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Chopra A; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Ford A; Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Chi X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Ruiz FX; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Arnold E; Center for Advanced Biotechnology and Medicine, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.; Department of Chemistry and Chemical Biology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.
Deng X; Department Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.; Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, OK 74078, USA.
Wang J; Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1434-1440. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Journal Article

MeSH Terms:

Coronavirus Papain-Like Proteases*/antagonists & inhibitors
Coronavirus Papain-Like Proteases*/chemistry
COVID-19*
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Coronavirus Protease Inhibitors*/administration & dosage
Coronavirus Protease Inhibitors*/chemistry
Coronavirus Protease Inhibitors*/pharmacology
Drug Design*
COVID-19 Drug Treatment*
Animals ; Mice ; Disease Models, Animal ; Administration, Oral ; Crystallography, X-Ray ; Structure-Activity Relationship ; Viral Load/drug effects ; Male ; Mice, Inbred C57BL ; Mice, Inbred BALB C

SCR Organism:

SARS-CoV-2 variants

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 26.

Tytuł:

Propofol improves survival in a murine model of sepsis via inhibiting Rab5a-mediated intracellular trafficking of TLR4.

Autorzy:

Zhou BW; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Zhang WJ; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Zhang FL; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Yang X; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Ding YQ; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Yao ZW; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Yan ZZ; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Zhao BC; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Chen XD; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Li C; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Liu KX; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China. .

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Źródło:

Journal of translational medicine [J Transl Med] 2024 Mar 28; Vol. 22 (1), pp. 316. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Journal Article

MeSH Terms:

Propofol*/pharmacology
Propofol*/therapeutic use
Propofol*/metabolism
Sepsis*/complications
Mice ; Humans ; Animals ; Toll-Like Receptor 4/metabolism ; Disease Models, Animal ; Macrophages/metabolism ; Lipopolysaccharides/pharmacology ; Lipopolysaccharides/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 27.

Tytuł:

Contribution of pudendal nerve injury to stress urinary incontinence in a male rat model.

Autorzy:

Maher S; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.
Gerber D; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Balog B; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.
Wang L; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.
Kuang M; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.
Hanzlicek B; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
Malakalapalli T; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.
Van Etten C; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA.
Khouri R Jr; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Damaser MS; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue ND20, Cleveland, OH, 44195, USA. .; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. .; Advanced Platform Technology Center, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA. .

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Źródło:

Scientific reports [Sci Rep] 2024 Mar 28; Vol. 14 (1), pp. 7444. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Journal Article

MeSH Terms:

Urinary Incontinence, Stress*/etiology
Urinary Incontinence, Stress*/pathology
Pudendal Nerve*/pathology
Peripheral Nerve Injuries*/complications
Urinary Incontinence*/complications
Male ; Rats ; Animals ; Rats, Sprague-Dawley ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 28.

Tytuł:

Taurine reduces microglia activation in the brain of aged senescence-accelerated mice by increasing the level of TREM2.

Autorzy:

Ahmed S; Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.; Department of Environmental Health, University of Fukui School of Medical Sciences, Eiheiji, Fukui, Japan.
Ma N; Graduate School of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan.; Institute of Traditional Chinese Medicine, Suzuka University of Medical Science, Suzuka, Mie, Japan.; Department of Acupuncture and Moxibution Science, Faculty of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan.
Kawanokuchi J; Graduate School of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan.; Institute of Traditional Chinese Medicine, Suzuka University of Medical Science, Suzuka, Mie, Japan.
Matsuoka K; Department of Acupuncture and Moxibution Science, Faculty of Health Science, Suzuka University of Medical Science, Suzuka, Mie, Japan.
Oikawa S; Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Kobayashi H; Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Hiraku Y; Department of Environmental Health, University of Fukui School of Medical Sciences, Eiheiji, Fukui, Japan.
Murata M; Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. .

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Źródło:

Scientific reports [Sci Rep] 2024 Mar 28; Vol. 14 (1), pp. 7427. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Journal Article

MeSH Terms:

Microglia*/metabolism
Alzheimer Disease*/metabolism
Mice ; Animals ; Taurine/pharmacology ; Taurine/metabolism ; Amyloid beta-Peptides/metabolism ; Brain/metabolism ; Water/metabolism ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 29.

Tytuł:

High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer.

Autorzy:

Topi G; Division of Cell and Experimental Pathology, Department of Translational Medicine, Lund University, Malmö, Sweden.; Department of Endocrinology, Skåne University Hospital, Malmö, Sweden.
Satapathy SR; Division of Cell and Experimental Pathology, Department of Translational Medicine, Lund University, Malmö, Sweden. shakti_.
Ghatak S; Division of Cell and Experimental Pathology, Department of Translational Medicine, Lund University, Malmö, Sweden.
Hellman K; Chemical Biology & Therapeutics Group, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Ek F; Chemical Biology & Therapeutics Group, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Olsson R; Chemical Biology & Therapeutics Group, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Ehrnström R; Department of Pathology, Skåne University Hospital, Malmö, Sweden.
Lydrup ML; Division of Surgery, Skåne University Hospital, Malmö, Sweden.
Sjölander A; Division of Cell and Experimental Pathology, Department of Translational Medicine, Lund University, Malmö, Sweden. .

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Źródło:

Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 28; Vol. 22 (1), pp. 198. Date of Electronic Publication: 2024 Mar 28.

Typ publikacji:

Journal Article

MeSH Terms:

Colonic Neoplasms*/pathology
Colorectal Neoplasms*/pathology
Humans ; Mice ; Animals ; Estrogen Receptor alpha ; beta Catenin/metabolism ; Zebrafish/metabolism ; Wnt Signaling Pathway ; Estrogen Receptor beta/genetics ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 30.

Tytuł:

Neuropathological changes in the TASTPM mouse model of Alzheimer's disease and their relation to hyperexcitability and cortical spreading depolarization.

Autorzy:

Gimeno-Ferrer F; Institute of Physiology 1/Neurophysiology, Jena University Hospital, 07740, Jena, Germany.
Eitner A; Department of Trauma, Hand and Reconstructive Surgery, Experimental Trauma Surgery, Jena University Hospital, 07740, Jena, Germany.
Noora N; Institute of Physiology 1/Neurophysiology, Jena University Hospital, 07740, Jena, Germany.
Bauer R; Institute of Molecular Cell Biology, CMB-Center for Molecular Biomedicine, Jena University Hospital, 07740, Jena, Germany.
Schmidt-Hieber C; Institute of Physiology 1/Neurophysiology, Jena University Hospital, 07740, Jena, Germany.
Schaible HG; Institute of Physiology 1/Neurophysiology, Jena University Hospital, 07740, Jena, Germany.
Richter F; Institute of Physiology 1/Neurophysiology, Jena University Hospital, 07740, Jena, Germany. .

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Źródło:

Scientific reports [Sci Rep] 2024 Mar 27; Vol. 14 (1), pp. 7224. Date of Electronic Publication: 2024 Mar 27.

Typ publikacji:

Journal Article

MeSH Terms:

Alzheimer Disease*/pathology
Male ; Female ; Mice ; Animals ; Amyloid beta-Protein Precursor ; Mice, Transgenic ; Mice, Inbred C57BL ; Amyloid beta-Peptides ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 31.

Tytuł:

Halofuginone prevents outer retinal degeneration in a mouse model of light-induced retinopathy.

Autorzy:

Miwa Y; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.; Aichi Animal Eye Clinic, Aichi, Japan.
Lee D; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Shoda C; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Nihon University School of Medicine, Tokyo, Japan.
Jeong H; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Negishi K; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Kurihara T; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

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Źródło:

PloS one [PLoS One] 2024 Mar 27; Vol. 19 (3), pp. e0300045. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Retinal Degeneration*/drug therapy
Retinal Degeneration*/etiology
Retinal Degeneration*/prevention & control
Piperidines*
Quinazolinones*
Mice ; Male ; Animals ; Disease Models, Animal ; Retina/pathology ; Electroretinography

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 32.

Tytuł:

Obesity differentially effects the somatosensory cortex and striatum of TgF344-AD rats.

Autorzy:

Ahmed M; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Lai AY; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada.
Hill ME; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada.
Ribeiro JA; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada.
Amiraslani A; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.
McLaurin J; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada. .; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada. .

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Źródło:

Scientific reports [Sci Rep] 2024 Mar 27; Vol. 14 (1), pp. 7235. Date of Electronic Publication: 2024 Mar 27.

Typ publikacji:

Journal Article

MeSH Terms:

Alzheimer Disease*/pathology
White Matter*/pathology
Rats ; Animals ; Somatosensory Cortex ; Brain/pathology ; Obesity/pathology ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 33.

Tytuł:

Changes in lipid metabolism track with the progression of neurofibrillary pathology in tauopathies.

Autorzy:

Olešová D; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Dobešová D; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic.
Majerová P; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Brumarová R; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic.
Kvasnička A; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic.
Kouřil Š; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic.
Stevens E; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Hanes J; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Fialová Ľ; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Michalicová A; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Piešťanský J; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Šinský J; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic.
Kaňovský P; Department of Neurology, University Hospital Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic.; Department of Neurology, Palacky University, Zdravotníků 7, Olomouc, 779 00, Czech Republic.
Friedecký D; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Zdravotníků 7, Olomouc, 779 00, Czech Republic. .
Kováč A; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 10, Slovak Republic. .

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Źródło:

Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 27; Vol. 21 (1), pp. 78. Date of Electronic Publication: 2024 Mar 27.

Typ publikacji:

Journal Article

MeSH Terms:

Tauopathies*/pathology
Alzheimer Disease*/pathology
Rats ; Animals ; Mice ; tau Proteins/genetics ; tau Proteins/metabolism ; Neurofibrillary Tangles/metabolism ; Lipid Metabolism ; Brain/metabolism ; Rats, Transgenic ; Mice, Transgenic ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 34.

Tytuł:

Effects of alendronate on cartilage lesions and micro-architecture deterioration of subchondral bone in patellofemoral osteoarthritic ovariectomized rats with patella-baja.

Autorzy:

Bei M; Department of Orthopedic Surgery, Beijing Jishuitan Hospital Affiliated to Capital Medical University, Xinjiekoudongjie 31, Xicheng Dis, Beijing, 100035, People's Republic of China.
Zheng Z; School of Public Health, North China University of Science and Technology, Tangshan, Hebei, People's Republic of China.
Xiao Y; The Department of Orthopedic Surgery, Wuhan Third Hospital, Tongren Hospital of Wuhan University, No. 241, Pengliuyang Road, Wuhan, 430000, People's Republic of China.
Liu N; School of Public Health, North China University of Science and Technology, Tangshan, Hebei, People's Republic of China.
Cao X; School of Public Health, North China University of Science and Technology, Tangshan, Hebei, People's Republic of China.
Tian F; School of Public Health, North China University of Science and Technology, Tangshan, Hebei, People's Republic of China.
Zhang L; Department of Orthopedic Surgery, Emergency General Hospital, Xibahenanli 29, Chaoyang District, Beijing, 100028, People's Republic of China.
Wu X; Department of Orthopedic Surgery, Beijing Jishuitan Hospital Affiliated to Capital Medical University, Xinjiekoudongjie 31, Xicheng Dis, Beijing, 100035, People's Republic of China. wuxinbao_.

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Źródło:

Journal of orthopaedic surgery and research [J Orthop Surg Res] 2024 Mar 25; Vol. 19 (1), pp. 197. Date of Electronic Publication: 2024 Mar 25.

Typ publikacji:

Journal Article

MeSH Terms:

Osteoarthritis, Knee*/diagnostic imaging
Osteoarthritis, Knee*/drug therapy
Osteoarthritis, Knee*/metabolism
Cartilage, Articular*/metabolism
Bone Resorption*/drug therapy
Humans ; Rats ; Female ; Animals ; Infant ; Alendronate/pharmacology ; Rats, Sprague-Dawley ; Patella/diagnostic imaging ; X-Ray Microtomography ; Disease Models, Animal ; Estrogens

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 35.

Tytuł:

The effect of early mobilisation (< 14 days) on pathophysiological and functional outcomes in animals with induced spinal cord injury: a systematic review with meta-analysis.

Autorzy:

Gray N; School of Medicine, University of Nottingham, Nottingham, UK. .
Shaikh J; School of Medicine, University of Nottingham, Nottingham, UK.
Cowley A; School of Medicine, University of Nottingham, Nottingham, UK.; Nottingham University Hospitals NHS Trust, Nottingham, UK.
Goosey-Tolfrey V; School of Sport, Exercise and Health Sciences, University of Loughborough, Loughborough, UK.
Logan P; School of Medicine, University of Nottingham, Nottingham, UK.
Quraishi N; Nottingham University Hospitals NHS Trust, Nottingham, UK.
Booth V; School of Medicine, University of Nottingham, Nottingham, UK.; Nottingham University Hospitals NHS Trust, Nottingham, UK.

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Źródło:

BMC neuroscience [BMC Neurosci] 2024 Mar 25; Vol. 25 (1), pp. 20. Date of Electronic Publication: 2024 Mar 25.

Typ publikacji:

Meta-Analysis; Systematic Review; Journal Article

MeSH Terms:

Early Ambulation*
Spinal Cord Injuries*
Humans ; Rats ; Mice ; Animals ; Recovery of Function/physiology ; Disease Models, Animal ; Spinal Cord

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 36.

Tytuł:

Neoadjuvant chemo-immunotherapy is improved with a novel pulsed electric field technology in an immune-cold murine model.

Autorzy:

Pastori C; Galvanize Therapeutics, Redwood City, CA, United States of America.
Nafie EHO; Galvanize Therapeutics, Redwood City, CA, United States of America.
Wagh MS; Galvanize Therapeutics, Redwood City, CA, United States of America.
Hunt SJ; Hospital of the University of Pennsylvania, Philadelphia, PA, United States of America.
Neal RE 2nd; Galvanize Therapeutics, Redwood City, CA, United States of America.

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Źródło:

PloS one [PLoS One] 2024 Mar 25; Vol. 19 (3), pp. e0299499. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Neoadjuvant Therapy*
Neoplasms*/pathology
Mice ; Humans ; Animals ; Disease Models, Animal ; Immunotherapy ; Cisplatin/therapeutic use ; Tumor Microenvironment

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 37.

Tytuł:

Human-derived bacterial strains mitigate colitis via modulating gut microbiota and repairing intestinal barrier function in mice.

Autorzy:

Dai J; Department of Intensive Care Unit, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P.R. China.
Jiang M; Department of Head and Neck Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P.R. China.
Wang X; Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lang T; Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wan L; Department of Stomatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
Wang J; Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .

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Źródło:

BMC microbiology [BMC Microbiol] 2024 Mar 23; Vol. 24 (1), pp. 96. Date of Electronic Publication: 2024 Mar 23.

Typ publikacji:

Journal Article

MeSH Terms:

Gastrointestinal Microbiome*
Colitis*/chemically induced
Colitis, Ulcerative*/chemically induced
Colitis, Ulcerative*/therapy
Enterococcus faecium*
Humans ; Animals ; Mice ; Intestinal Barrier Function ; RNA, Ribosomal, 16S/genetics ; Bacteroidetes ; Escherichia coli ; Mice, Inbred C57BL ; Disease Models, Animal ; Colon

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 38.

Tytuł:

A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis.

Autorzy:

Burelle C; Department of Medicine, Université de Montréal, Montreal, QC, Canada.; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Clapatiuc V; Department of Medicine, Université de Montréal, Montreal, QC, Canada.; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Deschênes S; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Cuillerier A; Faculty of Health Sciences and Medicine, University of Ottawa, Ottawa, OC, Canada.
De Loof M; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Higgins MÈ; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Boël H; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Daneault C; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Chouinard B; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Clavet MÉ; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Tessier N; Department of Medicine, Université de Montréal, Montreal, QC, Canada.; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Croteau I; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Chabot G; Research Center, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada.
Martel C; Department of Medicine, Université de Montréal, Montreal, QC, Canada.; Research Center, Montreal Heart Institute, Montreal, QC, Canada.
Sirois MG; Research Center, Montreal Heart Institute, Montreal, QC, Canada.; Department of Physiology and Pharmacology, Université de Montréal, Montreal, QC, Canada.
Lesage S; Research Center, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada.
Burelle Y; Faculty of Health Sciences and Medicine, University of Ottawa, Ottawa, OC, Canada.
Ruiz M; Research Center, Montreal Heart Institute, Montreal, QC, Canada. .; Department of Nutrition, Université de Montréal, Montreal, QC, Canada. .

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Źródło:

Communications biology [Commun Biol] 2024 Mar 22; Vol. 7 (1), pp. 356. Date of Electronic Publication: 2024 Mar 22.

Typ publikacji:

Journal Article

MeSH Terms:

Non-alcoholic Fatty Liver Disease*/genetics
Humans ; Male ; Female ; Animals ; Mice ; Sex Characteristics ; Disease Models, Animal ; Obesity/metabolism ; Lipoproteins

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 39.

Tytuł:

LINC00115 promotes chemoresistant breast cancer stem-like cell stemness and metastasis through SETDB1/PLK3/HIF1α signaling.

Autorzy:

Luo F; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Zhang M; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Sun B; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Xu C; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Yang Y; Pediatric Translational Medicine Institute, Department of Hematology & Oncology, Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai, 200127, China.
Zhang Y; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Li S; Pediatric Translational Medicine Institute, Department of Hematology & Oncology, Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai, 200127, China.
Chen G; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Chen C; Academy of Biomedical Engineering, the Third Affiliated Hospital, Kunming Medical University, Kunming, 650500, China. .
Li Y; Pediatric Translational Medicine Institute, Department of Hematology & Oncology, Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai, 200127, China. .
Feng H; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China. .

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Źródło:

Molecular cancer [Mol Cancer] 2024 Mar 22; Vol. 23 (1), pp. 60. Date of Electronic Publication: 2024 Mar 22.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/metabolism
Animals ; Humans ; Cell Line, Tumor ; Breast/metabolism ; Signal Transduction ; Paclitaxel/pharmacology ; Disease Models, Animal ; Neoplastic Stem Cells/metabolism ; Histone-Lysine N-Methyltransferase/metabolism ; Polo-like Kinases ; Protein Serine-Threonine Kinases/metabolism ; Tumor Suppressor Proteins/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 40.

Tytuł:

Rodent tests for psychiatric drugs get a rethink.

Autorzy:

Reardon S

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Źródło:

Science (New York, N.Y.) [Science] 2024 Mar 22; Vol. 383 (6689), pp. 1279. Date of Electronic Publication: 2024 Mar 21.

Typ publikacji:

Wiadomości

MeSH Terms:

Depression*/drug therapy
Rodentia*
Animal Experimentation*/ethics
Antidepressive Agents*/pharmacology
Antidepressive Agents*/therapeutic use
Animal Testing Alternatives*
Animals ; Disease Models, Animal ; Swimming ; Mice ; Rats

Periodyk

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 41.

Tytuł:

A Cocktail of Lipid Nanoparticle-mRNA Vaccines Broaden Immune Responses against β-Coronaviruses in a Murine Model.

Autorzy:

Zhang Y; Division of Hepatitis and Enterovirus Vaccines, Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.; Shanghai Biological Products Research Institute Co., Ltd., State Key Laboratory of Novel Vaccines for Emerging Infectious Diseases, Shanghai 200052, China.
Zhang J; Division of Hepatitis and Enterovirus Vaccines, Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China.
Li D; Shanghai Biological Products Research Institute Co., Ltd., State Key Laboratory of Novel Vaccines for Emerging Infectious Diseases, Shanghai 200052, China.
Mao Q; Division of Hepatitis and Enterovirus Vaccines, Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Li X; Shanghai Biological Products Research Institute Co., Ltd., State Key Laboratory of Novel Vaccines for Emerging Infectious Diseases, Shanghai 200052, China.
Liang Z; Division of Hepatitis and Enterovirus Vaccines, Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
He Q; Division of Hepatitis and Enterovirus Vaccines, Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, NMPA Key Laboratory for Quality Research and Evaluation of Biological Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.

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Źródło:

Viruses [Viruses] 2024 Mar 21; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 21.

Typ publikacji:

Journal Article

MeSH Terms:

Viral Vaccines*/genetics
Severe acute respiratory syndrome-related coronavirus*/genetics
Liposomes*
Nanoparticles*
Animals ; Mice ; Humans ; mRNA Vaccines ; SARS-CoV-2/genetics ; COVID-19 Vaccines ; Spike Glycoprotein, Coronavirus/genetics ; Disease Models, Animal ; Antibodies, Neutralizing ; RNA, Messenger/genetics ; Immunity ; Antibodies, Viral

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 42.

Tytuł:

Ebola virus disease sequelae and viral persistence in animal models: Implications for the future.

Autorzy:

Durant O; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Marzi A; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.

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Źródło:

PLoS pathogens [PLoS Pathog] 2024 Mar 21; Vol. 20 (3), pp. e1012065. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Hemorrhagic Fever, Ebola*
Ebolavirus*
Animals ; Disease Outbreaks ; Disease Progression ; Disease Models, Animal

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 43.

Tytuł:

Recovery of Water Homeostasis in Adenine-Induced Kidney Disease Is Mediated by Increased AQP2 Membrane Targeting.

Autorzy:

Atay JCL; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark.
Elsborg SH; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark.
Palmfeldt J; Research Unit for Molecular Medicine, Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark.
Nejsum LN; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark.
Nørregaard R; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark.; Department of Renal Medicine, Aarhus University Hospital, 8200 Aarhus N, Denmark.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.

Typ publikacji:

Journal Article

MeSH Terms:

Aquaporin 2*/metabolism
Renal Insufficiency, Chronic*/metabolism
Humans ; Mice ; Animals ; Water/metabolism ; Adenine/metabolism ; Disease Models, Animal ; Kidney/metabolism ; Inflammation/metabolism ; Fibrosis

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 44.

Tytuł:

Establishment of a lethal mouse model of emerging tick-borne orthonairovirus infections.

Autorzy:

Ariizumi T; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Tabata K; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.
Itakura Y; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.
Kobayashi H; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Hall WW; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.; National Virus Reference Laboratory, University College Dublin, Belfield, Dublin, 4, Ireland.; Global Virus Network, Baltimore, Maryland, United States of America.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Sasaki M; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.
Sawa H; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.; Global Virus Network, Baltimore, Maryland, United States of America.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; One Health Research Center, Hokkaido University, Sapporo, Japan.
Matsuno K; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; One Health Research Center, Hokkaido University, Sapporo, Japan.; Division of Risk Analysis and Management, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Orba Y; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; One Health Research Center, Hokkaido University, Sapporo, Japan.

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Źródło:

PLoS pathogens [PLoS Pathog] 2024 Mar 19; Vol. 20 (3), pp. e1012101. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Hemorrhagic Fever, Crimean*/pathology
Hemorrhagic Fever Virus, Crimean-Congo*
Nairovirus*
Tick-Borne Diseases*
Ticks*
Animals ; Humans ; Mice ; Disease Models, Animal ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Mice, Knockout

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 45.

Tytuł:

Beyond genetics: including the environmental dimension in amyloidosis mouse models for Alzheimer's disease.

Autorzy:

Van Hoecke L; VIB-UGent Center for Inflammation Research, Technologiepark-Zwijnaarde 71, Ghent, 9052, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, 9000, Belgium.
Vandenbroucke RE; VIB-UGent Center for Inflammation Research, Technologiepark-Zwijnaarde 71, Ghent, 9052, Belgium. .; Department of Biomedical Molecular Biology, Ghent University, Ghent, 9000, Belgium. .

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Źródło:

Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Mar 18; Vol. 12 (1), pp. 41. Date of Electronic Publication: 2024 Mar 18.

Typ publikacji:

Letter

MeSH Terms:

Alzheimer Disease*/genetics
Amyloidosis*/genetics
Mice ; Animals ; Amyloid beta-Peptides/genetics ; Disease Models, Animal

Opinia redakcyjna

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 46.

Tytuł:

Brain-derived endothelial cells are neuroprotective in a chronic cerebral hypoperfusion mouse model.

Autorzy:

Matsui Y; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Muramatsu F; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Nakamura H; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Noda Y; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Matsumoto K; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Kishima H; Department of Neurosurgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Takakura N; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan. .; World Premier Institute Immunology Frontier Research Center, Osaka University, Osaka, Japan. .; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Osaka, Japan. .; Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan. .

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Źródło:

Communications biology [Commun Biol] 2024 Mar 18; Vol. 7 (1), pp. 338. Date of Electronic Publication: 2024 Mar 18.

Typ publikacji:

Journal Article

MeSH Terms:

Ischemic Stroke*/metabolism
Brain Ischemia*/metabolism
Mice ; Animals ; Endothelial Cells/metabolism ; Brain/metabolism ; Disease Models, Animal ; Endothelium/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 47.

Tytuł:

Establishment of a hybrid model of atherosclerosis and acute colitis in ApoE-/- mice.

Autorzy:

Chen K; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.; Department of Ultrasound, Nanjing Drum Tower Hospital, Nanjing, P. R. China.
Zhang S; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Cui G; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Zhang X; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Song Y; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.; Department of Ultrasound, Foshan First People's Hospital, Foshan, P. R. China.
Zheng J; Department of Traditional Chinese Medicine, Peking University Shenzhen Hospital, Shenzhen, P. R. China.
Chen Y; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Zheng T; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.

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Źródło:

PloS one [PLoS One] 2024 Mar 18; Vol. 19 (3), pp. e0289820. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Atherosclerosis*/diagnostic imaging
Atherosclerosis*/genetics
Plaque, Atherosclerotic*/diagnostic imaging
Plaque, Atherosclerotic*/complications
Colitis*/complications
Inflammatory Bowel Diseases*/complications
Humans ; Mice ; Animals ; Mice, Knockout ; Mice, Knockout, ApoE ; Diet, High-Fat/adverse effects ; Apolipoproteins E/genetics ; Mice, Inbred C57BL ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 48.

Tytuł:

LEDT and Idebenone treatment modulate autophagy and improve regenerative capacity in the dystrophic muscle through an AMPK-pathway.

Autorzy:

Silva HNMD; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Fernandes EM; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Pereira VA; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Mizobuti DS; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Covatti C; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Rocha GLD; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Minatel E; Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil.

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Źródło:

PloS one [PLoS One] 2024 Mar 18; Vol. 19 (3), pp. e0300006. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Muscle, Skeletal*/metabolism
Muscular Dystrophy, Duchenne*/drug therapy
Muscular Dystrophy, Duchenne*/metabolism
Ubiquinone/*analogs & derivatives
Animals ; Mice ; Humans ; Mice, Inbred mdx ; AMP-Activated Protein Kinases/metabolism ; Autophagy ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 49.

Tytuł:

Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses.

Autorzy:

Xu J; Department of Gastroenterology and Hepatology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Xu H; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Guo X; Department of Gastroenterology and Hepatology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Zhao H; Department of Gastroenterology and Hepatology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Wang J; Department of Gastroenterology and Hepatology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Li J; Department of Gastroenterology and Hepatology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
He J; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Huang H; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Huang C; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Zhao C; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Li Y; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.
Zhou Y; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China. .
Peng Y; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China. .
Nie Y; Department of Gastroenterology and Hepatology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China. .

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Źródło:

BMC microbiology [BMC Microbiol] 2024 Mar 18; Vol. 24 (1), pp. 91. Date of Electronic Publication: 2024 Mar 18.

Typ publikacji:

Journal Article

MeSH Terms:

Colitis*/chemically induced
Colitis*/prevention & control
Inflammatory Bowel Diseases*
Probiotics*/pharmacology
Humans ; Animals ; Mice ; Anti-Bacterial Agents/adverse effects ; Th2 Cells ; Th17 Cells ; Inflammation ; Immunity ; Mice, Inbred C57BL ; Disease Models, Animal

Czasopismo naukowe

• na półce

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Skocz do pozycji: 50.

Tytuł:

Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer's Disease Models.

Autorzy:

Wang R; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; School of Integrated Chinese and Western Medicine, Dalian Medical University, Dalian 116044, China.
Kang S; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; School of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China.
Zhao Z; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; School of Integrated Chinese and Western Medicine, Dalian Medical University, Dalian 116044, China.
Jin L; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
Cui X; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
Chen L; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.
Schachner M; Keck Center for Collaborative Neuroscience and Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
Li S; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; Department of Biochemistry, School of Basic Medical Science, Dalian Medical University, Dalian 116044, China.
Guo Y; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.; Department of Microecology, School of Basic Medical Science, Dalian Medical University, Dalian 116044, China.
Zhao J; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Mar 17; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 17.

Typ publikacji:

Journal Article

MeSH Terms:

Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Neural Cell Adhesion Molecule L1*
Neurodegenerative Diseases*
Neuroblastoma*
Caffeic Acids*
Succinates*
Humans ; Mice ; Animals ; Amyloid Precursor Protein Secretases/genetics ; Amyloid Precursor Protein Secretases/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Mice, Transgenic ; Disease Models, Animal ; Aspartic Acid Endopeptidases/metabolism ; Amyloid beta-Peptides/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły