- Tytuł:
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Clonal haematopoiesis and risk of chronic liver
disease . - Autorzy:
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Wong WJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Emdin C; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Bick AG; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Zekavat SM; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Yale University School of Medicine, New Haven, CT, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Niroula A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Department of Laboratory Medicine, Lund University, Lund, Sweden.
Pirruccello JP; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Division of Cardiology, University of California San Francisco, San Francisco, CA, USA.
Dichtel L; Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Griffin G; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Department of Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.
Uddin MM; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Gibson CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Kovalcik V; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Lin AE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
McConkey ME; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Vromman A; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Sellar RS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Haematology, UCL Cancer Institute, London, UK.
Kim PG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
Agrawal M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Weinstock J; Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Long MT; Section of Gastroenterology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Yu B; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Banerjee R; Perspectum Ltd, Oxford, UK.
Nicholls RC; Perspectum Ltd, Oxford, UK.
Dennis A; Perspectum Ltd, Oxford, UK.
Kelly M; Perspectum Ltd, Oxford, UK.
Loh PR; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
McCarroll S; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Vasan RS; The University of Texas School of Public Health San Antonio, San Antonio, TX, USA.; Framingham Heart Study of the NHLBI and Boston University School of Medicine, Framingham, MA, USA.; The University of Texas Health Science Center, San Antonio, TX, USA.
Jaiswal S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Johnson AD; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, MA, USA.
Chung RT; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Liver Center, Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Corey K; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Liver Center, Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Levy D; Framingham Heart Study of the NHLBI and Boston University School of Medicine, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Ballantyne C; Department of Medicine, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Ebert BL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Benjamin_.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA. Benjamin_.; Department of Medicine, Harvard Medical School, Boston, MA, USA. Benjamin_.; Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Boston, MA, USA. Benjamin_.
Natarajan P; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA. .; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. .; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. .; Department of Medicine, Harvard Medical School, Boston, MA, USA. . - Pokaż więcej
- Corporate Authors:
- NHLBI TOPMed Hematology Working Group
- Źródło:
- Nature [Nature] 2023 Apr; Vol. 616 (7958), pp. 747-754. Date of Electronic Publication: 2023 Apr 12.
- Typ publikacji:
- Journal Article
- MeSH Terms:
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Clonal Hematopoiesis*/genetics
Hepatitis*/genetics
Liver Cirrhosis*/geneticsDisease Susceptibility *
Animals ; Mice ; Inflammation/genetics ; Non-alcoholic Fatty LiverDisease /genetics ; Odds Ratio ;Disease Progression
Czasopismo naukowe
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