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Wyświetlanie 1-17 z 17
Czasopismo naukowe
Tytuł:
Correction: Brosch et al. Glucose and Inositol Transporters, SLC5A1 and SLC5A3, in Glioblastoma Cell Migration. Cancers 2022, 14 , 5794.
Autorzy:
Brosch PK; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Korsa T; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.; Fraunhofer Institute for Biomedical Engineering (IBMT), 66280 Sulzbach, Germany.
Taban D; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Eiring P; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Kreisz P; Julius-von-Sachs Institute, University of Würzburg, 97082 Würzburg, Germany.
Hildebrand S; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Neubauer J; Fraunhofer Institute for Biomedical Engineering (IBMT), 66280 Sulzbach, Germany.
Zimmermann H; Fraunhofer Institute for Biomedical Engineering (IBMT), 66280 Sulzbach, Germany.; Department of Molecular and Cellular Biotechnology, Saarland University, 66123 Saarbrücken, Germany.; Faculty of Marine Science, Universidad Católica del Norte, Coquimbo 1281, Chile.
Sauer M; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Shirakashi R; Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan.
Djuzenova CS; Department of Radiation Oncology, University Hospital of Würzburg, 97080 Würzburg, Germany.
Sisario D; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Sukhorukov VL; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
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Źródło:
Cancers [Cancers (Basel)] 2023 Oct 25; Vol. 15 (21). Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Published Erratum
Tytuł:
Glucose and Inositol Transporters, SLC5A1 and SLC5A3, in Glioblastoma Cell Migration.
Autorzy:
Brosch PK; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Korsa T; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.; Fraunhofer Institute for Biomedical Engineering (IBMT), 66280 Sulzbach, Germany.
Taban D; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Eiring P; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Hildebrand S; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Neubauer J; Fraunhofer Institute for Biomedical Engineering (IBMT), 66280 Sulzbach, Germany.
Zimmermann H; Fraunhofer Institute for Biomedical Engineering (IBMT), 66280 Sulzbach, Germany.; Department of Molecular and Cellular Biotechnology, Saarland University, 66123 Saarbrücken, Germany.; Faculty of Marine Science, Universidad Católica del Norte, Coquimbo 1281, Chile.
Sauer M; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Shirakashi R; Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan.
Djuzenova CS; Department of Radiation Oncology, University Hospital of Würzburg, 97080 Würzburg, Germany.
Sisario D; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Sukhorukov VL; Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
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Źródło:
Cancers [Cancers (Basel)] 2022 Nov 24; Vol. 14 (23). Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Opposite effects of the triple target (DNA-PK/PI3K/mTOR) inhibitor PI-103 on the radiation sensitivity of glioblastoma cell lines proficient and deficient in DNA-PKcs.
Autorzy:
Djuzenova CS; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. djuzenova_.
Fischer T; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Katzer A; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Sisario D; Department of Biotechnology and Biophysics, University of Würzburg, Würzburg, Germany.
Korsa T; Department of Biotechnology and Biophysics, University of Würzburg, Würzburg, Germany.
Steussloff G; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Sukhorukov VL; Department of Biotechnology and Biophysics, University of Würzburg, Würzburg, Germany.
Flentje M; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
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Źródło:
BMC cancer [BMC Cancer] 2021 Nov 11; Vol. 21 (1), pp. 1201. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Neoplasms/*therapy
DNA-Activated Protein Kinase/*deficiency
Furans/*pharmacology
Glioblastoma/*therapy
Pyridines/*pharmacology
Pyrimidines/*pharmacology
Radiation Tolerance/*drug effects
Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Chemoradiotherapy/methods ; DNA-Activated Protein Kinase/antagonists & inhibitors ; DNA-Activated Protein Kinase/genetics ; DNA-Activated Protein Kinase/metabolism ; Furans/therapeutic use ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Pyridines/therapeutic use ; Pyrimidines/therapeutic use ; Radiation Tolerance/genetics ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy.
Autorzy:
Memmel S; Department of Radiation Oncology, University Hospital Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Sisario D; Lehrstuhl für Biotechnologie und Biophysik, Biozentrum, Universität Würzburg, 97074, Würzburg, Germany.
Zimmermann H; Fraunhofer Institute for Biomedical Engineering (IBMT), Joseph-von-Fraunhofer-Weg 1, 66280, Sulzbach, Germany.; Molekulare und Zellulare Biotechnologie/Nanotechnologie, Universität des Saarlandes, Campus Saarbrücken, 66123, Saarbrücken, Germany.; Marine Sciences, Universidad Catolica del Norte, Casa Central, Angamos 0610, Antafogasta/Coquimbo, Chile.
Sauer M; Lehrstuhl für Biotechnologie und Biophysik, Biozentrum, Universität Würzburg, 97074, Würzburg, Germany.
Sukhorukov VL; Lehrstuhl für Biotechnologie und Biophysik, Biozentrum, Universität Würzburg, 97074, Würzburg, Germany.
Djuzenova CS; Department of Radiation Oncology, University Hospital Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. djuzenova_.
Flentje M; Department of Radiation Oncology, University Hospital Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. Flentje_.
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2020 Jan 28; Vol. 21 (1), pp. 27. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Algorithms*
DNA Repair*
Image Processing, Computer-Assisted/*methods
Microscopy, Confocal/*methods
Microscopy, Fluorescence/*methods
Cell Line, Tumor ; Cell Nucleus/metabolism ; DNA Breaks, Double-Stranded ; Histones/analysis ; Histones/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Differential effects of the Akt inhibitor MK-2206 on migration and radiation sensitivity of glioblastoma cells.
Autorzy:
Djuzenova CS; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. djuzenova_.
Fiedler V; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Memmel S; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Katzer A; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Sisario D; Department of Biotechnology and Biophysics, University of Würzburg, 97074, Würzburg, Germany.
Brosch PK; Department of Biotechnology and Biophysics, University of Würzburg, 97074, Würzburg, Germany.
Göhrung A; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Frister S; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Zimmermann H; Fraunhofer-Institut für Biomedizinische Technik, Joseph-von-Fraunhofer-Weg 1, 66280, Sulzbach, Germany.; Professur für Molekulare und Zelluläre Biotechnologie/Nanotechnologie, Universität des Saarlandes, Campus Saarbrücken, 66123, Saarbrücken, Germany.; Marine Sciences, Universidad Católica del Norte, Casa Central, Angamos 0610, Antafogasta/Coquimbo, Chile.
Flentje M; Department of Radiation Oncology, University Hospital of Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany.
Sukhorukov VL; Department of Biotechnology and Biophysics, University of Würzburg, 97074, Würzburg, Germany.
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Źródło:
BMC cancer [BMC Cancer] 2019 Apr 03; Vol. 19 (1), pp. 299. Date of Electronic Publication: 2019 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Neoplasms/*metabolism
Glioblastoma/*metabolism
Heterocyclic Compounds, 3-Ring/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Radiation-Sensitizing Agents/*pharmacology
Brain Neoplasms/genetics ; Brain Neoplasms/therapy ; Cell Cycle/drug effects ; Cell Cycle/radiation effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Movement/radiation effects ; DNA Damage ; Furans/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/radiation effects ; Glioblastoma/genetics ; Glioblastoma/therapy ; Humans ; Mutation ; PTEN Phosphohydrolase/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Pyridines/pharmacology ; Pyrimidines/pharmacology ; Radiation Tolerance/drug effects ; Single-Cell Analysis ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
A prospective study on histone γ-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome.
Autorzy:
Djuzenova CS; Department of Radiation Oncology, University Hospital, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. djuzenova_.
Zimmermann M; Department of Radiation Oncology, University Hospital, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. Zimmerman_.
Katzer A; Department of Radiation Oncology, University Hospital, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. Katzer_.
Fiedler V; Department of Radiation Oncology, University Hospital, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. Fiedler_.
Distel LV; Department of Radiation Oncology, University of Erlangen-Nürnberg, Erlangen, Germany. .
Gasser M; Department of Surgery I, University Hospital, Würzburg, Germany. Gasser_.
Waaga-Gasser AM; Department of Surgery I, University Hospital, Würzburg, Germany. Waaga_.
Flentje M; Department of Radiation Oncology, University Hospital, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. Flentje_.
Polat B; Department of Radiation Oncology, University Hospital, Josef-Schneider-Strasse 11, 97080, Würzburg, Germany. Polat_.; Comprehensive Cancer Center Mainfranken, University Hospital, Würzburg, Germany. Polat_.
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Źródło:
BMC cancer [BMC Cancer] 2015 Nov 06; Vol. 15, pp. 856. Date of Electronic Publication: 2015 Nov 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression*
Histones/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Rectal Neoplasms/*genetics
Adult ; Aged ; Case-Control Studies ; DNA Damage/radiation effects ; Female ; Histones/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Leukocytes, Mononuclear/metabolism ; Male ; Middle Aged ; Neoplasm Staging ; Prospective Studies ; Radiation Tolerance/genetics ; Rectal Neoplasms/pathology ; Rectal Neoplasms/radiotherapy ; Treatment Outcome ; Tumor Suppressor p53-Binding Protein 1 ; Young Adult
Czasopismo naukowe
Tytuł:
Simultaneous perturbation of the MAPK and the PI3K/mTOR pathways does not lead to increased radiosensitization.
Autorzy:
Kuger S; Department of Radiation Oncology, University Hospital of Würzburg, Würzburg, Germany. .
Flentje M; Department of Radiation Oncology, University Hospital of Würzburg, Würzburg, Germany.
Djuzenova CS; Department of Radiation Oncology, University Hospital of Würzburg, Würzburg, Germany.
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Źródło:
Radiation oncology (London, England) [Radiat Oncol] 2015 Oct 24; Vol. 10, pp. 214. Date of Electronic Publication: 2015 Oct 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phosphoinositide-3 Kinase Inhibitors*
Mitogen-Activated Protein Kinases/*antagonists & inhibitors
Radiation Tolerance/*physiology
Radiation-Sensitizing Agents/*pharmacology
TOR Serine-Threonine Kinases/*antagonists & inhibitors
Antineoplastic Agents/pharmacology ; Benzimidazoles/pharmacology ; Blotting, Western ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Synergism ; Enzyme Inhibitors/pharmacology ; Humans ; Imidazoles/pharmacology ; Quinolines/pharmacology ; Radiation Tolerance/drug effects ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Distinct increased outliers among 136 rectal cancer patients assessed by γH2AX.
Autorzy:
Kroeber J; Department of Radiation Oncology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany. .
Wenger B; Department of Radiation Oncology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany. .
Schwegler M; Department of Radiation Oncology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany. .
Daniel C; Department of Nephropathology, University Hospitals and Friedrich-Alexander-University Erlangen-Nürnberg Institute of Pathology, 91054, Erlangen, Germany. .
Schmidt M; Department of Radiation Oncology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany. .
Djuzenova CS; Department of Radiation Oncology, University of Würzburg, 97080, Würzburg, Germany. Djuzenova_.
Polat B; Department of Radiation Oncology, University of Würzburg, 97080, Würzburg, Germany. polat_.
Flentje M; Department of Radiation Oncology, University of Würzburg, 97080, Würzburg, Germany. Flentje_.
Fietkau R; Department of Radiation Oncology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany. .
Distel LV; Department of Radiation Oncology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany. .
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Źródło:
Radiation oncology (London, England) [Radiat Oncol] 2015 Feb 11; Vol. 10, pp. 36. Date of Electronic Publication: 2015 Feb 11.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Damage*
DNA Repair*
Histones/*metabolism
Lymphocytes/*metabolism
Rectal Neoplasms/*metabolism
Rectum/*metabolism
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Female ; Fluorescent Antibody Technique ; Follow-Up Studies ; Humans ; Lymphocytes/pathology ; Lymphocytes/radiation effects ; Male ; Middle Aged ; Prospective Studies ; Radiation Tolerance/genetics ; Rectal Neoplasms/pathology ; Rectal Neoplasms/radiotherapy ; Rectum/pathology
Czasopismo naukowe
Tytuł:
Cell surface area and membrane folding in glioblastoma cell lines differing in PTEN and p53 status.
Autorzy:
Memmel S; Lehrstuhl für Biotechnologie und Biophysik, Universität Würzburg, Am Hubland, Würzburg, Germany.
Sukhorukov VL; Lehrstuhl für Biotechnologie und Biophysik, Universität Würzburg, Am Hubland, Würzburg, Germany.
Höring M; Lehrstuhl für Biotechnologie und Biophysik, Universität Würzburg, Am Hubland, Würzburg, Germany.
Westerling K; Lehrstuhl für Biotechnologie und Biophysik, Universität Würzburg, Am Hubland, Würzburg, Germany.
Fiedler V; Department of Radiation Oncology, University Hospital Würzburg, Würzburg, Germany.
Katzer A; Department of Radiation Oncology, University Hospital Würzburg, Würzburg, Germany.
Krohne G; Elektronenmikroskopie, Biozentrum, Universität Würzburg, Am Hubland, Würzburg, Germany.
Flentje M; Department of Radiation Oncology, University Hospital Würzburg, Würzburg, Germany.
Djuzenova CS; Department of Radiation Oncology, University Hospital Würzburg, Würzburg, Germany.
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Źródło:
PloS one [PLoS One] 2014 Jan 31; Vol. 9 (1), pp. e87052. Date of Electronic Publication: 2014 Jan 31 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Cell Membrane/*metabolism
PTEN Phosphohydrolase/*genetics
Tumor Suppressor Protein p53/*genetics
Blotting, Western ; Cell Line ; Cell Line, Tumor ; Cell Membrane/chemistry ; Cell Membrane/ultrastructure ; Cell Size/drug effects ; Electric Capacitance ; Fatty Acid Synthases/metabolism ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Glioblastoma/pathology ; HEK293 Cells ; Humans ; Hypotonic Solutions/pharmacology ; Isotonic Solutions/pharmacology ; Microscopy, Electron, Scanning ; Osmolar Concentration ; PTEN Phosphohydrolase/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-mdm2/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
    Wyświetlanie 1-17 z 17

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