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Wyszukujesz frazę ""Dobrowolski, Curtis"" wg kryterium: Autor


Tytuł :
A Phase 1/2 Randomized, Placebo-Controlled Trial of Romidespin in Persons With HIV-1 on Suppressive Antiretroviral Therapy.
Autorzy :
McMahon DK; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Zheng L; Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Cyktor JC; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Aga E; Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Macatangay BJ; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Godfrey C; National Institutes of Health, Bethesda, Maryland, USA.
Para M; Ohio State University, Columbus, Ohio, USA.
Mitsuyasu RT; University of California Los Angeles, Los Angeles, California, USA.
Hesselgesser J; Gilead Sciences, Inc., Foster City, California, USA.
Dragavon J; University of Washington, Seattle, Washington, USA.
Dobrowolski C; Case Western Reserve University, Cleveland, Ohio, USA.
Karn J; Case Western Reserve University, Cleveland, Ohio, USA.
Acosta EP; University of Alabama at Birmingham, Birmingham, Alabama, USA.
Gandhi RT; Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Mellors JW; University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2021 Aug 16; Vol. 224 (4), pp. 648-656.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A phase I/II randomized, placebo-controlled trial of romidepsin in persons with HIV-1 on suppressive antiretroviral therapy to assess safety and activation of HIV-1 expression (A5315).
Autorzy :
McMahon, Deborah K (AUTHOR)
Zheng, Lu (AUTHOR)
Cyktor, Joshua C (AUTHOR)
Aga, Evgenia (AUTHOR)
Macatangay, Bernard J (AUTHOR)
Godfrey, Catherine (AUTHOR)
Para, Michael (AUTHOR)
Mitsuyasu, Ronald T (AUTHOR)
Hesselgesser, Joseph (AUTHOR)
Dragavon, Joan (AUTHOR)
Dobrowolski, Curtis (AUTHOR)
Karn, Jonathan (AUTHOR)
Acosta, Edward P (AUTHOR)
Gandhi, Rajesh T (AUTHOR)
Mellors, John W (AUTHOR)
ACTG A5315 Team (CORPORATE AUTHOR)
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Źródło :
Journal of Infectious Diseases. 8/15/2021, Vol. 224 Issue 4, p648-656. 9p.
Czasopismo naukowe
Tytuł :
A phase I/II randomized, placebo-controlled trial of romidepsin in persons with HIV-1 on suppressive antiretroviral therapy to assess safety and activation of HIV-1 expression (A5315).
Autorzy :
McMahon DK; University of Pittsburgh, Pittsburgh, PA.
Zheng L; Harvard TH Chan School of Public Health, Boston, MA.
Cyktor JC; University of Pittsburgh, Pittsburgh, PA.
Aga E; Harvard TH Chan School of Public Health, Boston, MA.
Macatangay BJ; University of Pittsburgh, Pittsburgh, PA.
Godfrey C; National Institutes of Health, Bethesda, MD.
Para M; The Ohio State University, Columbus, OH.
Mitsuyasu RT; University of California Los Angeles, Los Angeles, CA.
Hesselgesser J; Gilead Sciences, Inc., Foster City, CA.
Dragavon J; University of Washington, Seattle, WA.
Dobrowolski C; Case Western Reserve University, Cleveland, OH.
Karn J; Case Western Reserve University, Cleveland, OH.
Acosta EP; University of Alabama at Birmingham, Birmingham, AL.
Gandhi RT; Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Mellors JW; University of Pittsburgh, Pittsburgh, PA.
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Corporate Authors :
ACTG A5315 Team
Źródło :
The Journal of infectious diseases [J Infect Dis] 2020 Dec 22. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Entry of Polarized Effector Cells into Quiescence Forces HIV Latency.
Autorzy :
Dobrowolski C; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Valadkhan S; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Graham AC; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Shukla M; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Ciuffi A; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Telenti A; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, USA.
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA .
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Źródło :
MBio [mBio] 2019 Mar 26; Vol. 10 (2). Date of Electronic Publication: 2019 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Activation*
Virus Latency*
CD4-Positive T-Lymphocytes/*virology
HIV/*physiology
HIV Infections/*virology
T-Lymphocyte Subsets/*virology
Cells, Cultured ; Cytokines/metabolism ; Flow Cytometry ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł :
The Glucocorticoid Receptor Is a Critical Regulator of HIV Latency in Human Microglial Cells.
Autorzy :
Alvarez-Carbonell D; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Ye F; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Ramanath N; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Dobrowolski C; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA. .
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Źródło :
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2019 Mar; Vol. 14 (1), pp. 94-109. Date of Electronic Publication: 2018 Jul 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV/*physiology
HIV Infections/*virology
Microglia/*virology
Receptors, Glucocorticoid/*metabolism
Virus Latency/*physiology
Cell Culture Techniques ; Cells, Cultured ; HIV Infections/metabolism ; Humans ; Microglia/metabolism ; Virus Activation ; Virus Replication/physiology
Czasopismo naukowe
Tytuł :
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir.
Autorzy :
Das B; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
Dobrowolski C; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
Luttge B; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
Valadkhan S; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
Chomont N; Université de Montréal Hospital Research Centre, Université de Montréal, Montreal, QC H3T 1J4, Canada.; Department of Microbiology, Infectious Diseases, and Immunology, Université de Montréal, Montreal, QC H2X 3H8, Canada.
Johnston R; amfAR, The Foundation for AIDS Research, New York, NY 10005.
Bacchetti P; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158.
Hoh R; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA 94110.
Gandhi M; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA 94110.
Deeks SG; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA 94110.
Scully E; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD 21218.
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH 44106; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Aug 14; Vol. 115 (33), pp. E7795-E7804. Date of Electronic Publication: 2018 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Sex Characteristics*
Estrogen Receptor Modulators/*pharmacology
Estrogen Receptor alpha/*agonists
HIV-1/*physiology
Transcription, Genetic/*drug effects
Virus Latency/*drug effects
Adult ; Estrogen Receptor alpha/metabolism ; Female ; Humans ; Jurkat Cells ; Male ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł :
A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs.
Autorzy :
Schlatzer D; Center for Proteomics and Bioinformatics, Department of Nutrition, ‡Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University , Cleveland, Ohio 44106, United States.
Haqqani AA; Center for Proteomics and Bioinformatics, Department of Nutrition, ‡Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University , Cleveland, Ohio 44106, United States.
Li X; Center for Proteomics and Bioinformatics, Department of Nutrition, ‡Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University , Cleveland, Ohio 44106, United States.
Dobrowolski C; Center for Proteomics and Bioinformatics, Department of Nutrition, ‡Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University , Cleveland, Ohio 44106, United States.
Chance MR; Center for Proteomics and Bioinformatics, Department of Nutrition, ‡Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University , Cleveland, Ohio 44106, United States.
Tilton JC; Center for Proteomics and Bioinformatics, Department of Nutrition, ‡Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University , Cleveland, Ohio 44106, United States.
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Źródło :
Analytical chemistry [Anal Chem] 2017 May 16; Vol. 89 (10), pp. 5325-5332. Date of Electronic Publication: 2017 May 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Tandem Mass Spectrometry*
CD4-Positive T-Lymphocytes/*virology
HIV-1/*metabolism
gag Gene Products, Human Immunodeficiency Virus/*analysis
Anti-HIV Agents/therapeutic use ; Antibodies, Monoclonal/immunology ; CD4-Positive T-Lymphocytes/cytology ; Chromatography, High Pressure Liquid ; Genotype ; HIV Infections/drug therapy ; HIV Infections/pathology ; HIV Infections/virology ; HIV-1/genetics ; HIV-1/isolation & purification ; Humans ; Immunoprecipitation ; Limit of Detection ; Peptides/analysis ; Peptides/chemistry ; gag Gene Products, Human Immunodeficiency Virus/immunology ; gag Gene Products, Human Immunodeficiency Virus/metabolism
Czasopismo naukowe
Tytuł :
Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.
Autorzy :
Nguyen K; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Das B; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Dobrowolski C; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA .
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Źródło :
MBio [mBio] 2017 Feb 28; Vol. 8 (1). Date of Electronic Publication: 2017 Feb 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Processing, Post-Translational*
Virus Latency*
Enhancer of Zeste Homolog 2 Protein/*metabolism
HIV-1/*physiology
Histocompatibility Antigens/*metabolism
Histone-Lysine N-Methyltransferase/*metabolism
Histones/*metabolism
Cells, Cultured ; Chromatin Immunoprecipitation ; Humans ; Methylation
Czasopismo naukowe
Tytuł :
Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells.
Autorzy :
Alvarez-Carbonell D; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA.
Garcia-Mesa Y; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA.
Milne S; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA.
Das B; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA.
Dobrowolski C; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA.
Rojas R; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA.
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University, 10900 Euclid Ave., SOM WRT 200, Cleveland, OH, 44106, USA. .
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Źródło :
Retrovirology [Retrovirology] 2017 Feb 06; Vol. 14 (1), pp. 9. Date of Electronic Publication: 2017 Feb 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Virus Latency*
HIV-1/*physiology
Microglia/*virology
Toll-Like Receptor 3/*metabolism
Animals ; Cell Line ; Cells, Cultured ; Humans ; Lipopolysaccharides/pharmacology ; Microglia/drug effects ; Monocytes/drug effects ; Monocytes/virology ; NF-kappa B/metabolism ; Poly I-C/pharmacology ; RNA, Bacterial/pharmacology ; RNA, Ribosomal/pharmacology ; Rats ; Signal Transduction/drug effects ; T-Lymphocytes/drug effects ; T-Lymphocytes/virology ; Toll-Like Receptor 2/agonists ; Toll-Like Receptor 3/agonists ; Toll-Like Receptor 4/agonists ; Toll-Like Receptors/agonists ; Virus Activation
Czasopismo naukowe
Tytuł :
Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system.
Autorzy :
Garcia-Mesa Y; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Jay TR; Department of Neurosciences, Case Western Reserve University, Cleveland, OH, 44106, USA.
Checkley MA; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Luttge B; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Dobrowolski C; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Valadkhan S; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
Landreth GE; Department of Neurosciences, Case Western Reserve University, Cleveland, OH, 44106, USA.
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Alvarez-Carbonell D; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH, 44106, USA. .
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Źródło :
Journal of neurovirology [J Neurovirol] 2017 Feb; Vol. 23 (1), pp. 47-66. Date of Electronic Publication: 2016 Nov 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Founder Effect*
Transformation, Genetic*
Antigens, Viral, Tumor/*genetics
Microglia/*pathology
Adult ; Animals ; Antigens, Viral, Tumor/metabolism ; Biomarkers/metabolism ; Brain/metabolism ; Brain/pathology ; Brain/virology ; CD11b Antigen/genetics ; CD11b Antigen/metabolism ; Cell Movement ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Humans ; Lentivirus/genetics ; Lentivirus/metabolism ; Macaca ; Mice ; Microglia/metabolism ; Microglia/virology ; Phagocytosis ; Primary Cell Culture ; Rats ; Receptors, Purinergic P2Y12/genetics ; Receptors, Purinergic P2Y12/metabolism ; Receptors, Transforming Growth Factor beta/genetics ; Receptors, Transforming Growth Factor beta/metabolism
Czasopismo naukowe

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