The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis.
Autorzy:
Mabbott NA; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. Bradford BM; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. Pal R; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. Young R; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. DonaldsonDS; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase.
Autorzy:
DonaldsonDS; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Easter Bush, EH25 9RG, Midlothian, United Kingdom. david.donaldson@roslin.ed.ac.uk. Bradford BM; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Easter Bush, EH25 9RG, Midlothian, United Kingdom. Else KJ; Lydia Becker Institute of Immunology and Inflammation, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PL, United Kingdom. Mabbott NA; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Easter Bush, EH25 9RG, Midlothian, United Kingdom. .
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Źródło:
Scientific reports [Sci Rep] 2020 Mar 12; Vol. 10 (1), pp. 4554. Date of Electronic Publication: 2020 Mar 12.
Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice.
Autorzy:
Sánchez-Quintero A; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9RG, United Kingdom. Bradford BM; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9RG, United Kingdom. Maizels R; Wellcome Trust Centre for Molecular Parasitology, Institute for Infection, Immunity and Inflammation, Sir Graeme Davies Building, 120 University Place, Glasgow, G12 8TA, United Kingdom. DonaldsonDS; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9RG, United Kingdom. Mabbott NA; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9RG, United Kingdom. .
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Scientific reports [Sci Rep] 2019 Apr 30; Vol. 9 (1), pp. 6674. Date of Electronic Publication: 2019 Apr 30.
Increased susceptibility to oral Trichuris muris infection in the specific absence of CXCR5 cells.
Autorzy:
Bradford BM; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Edinburgh, UK. DonaldsonDS; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Edinburgh, UK. Forman R; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. Else KJ; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. Mabbott NA; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Edinburgh, UK.
Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.
Autorzy:
DonaldsonDS; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, United Kingdom. Sehgal A; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, United Kingdom. Rios D; Dept. Pathology, Emory University School of Medicine, Atlanta, Georgia, United States of America. Williams IR; Dept. Pathology, Emory University School of Medicine, Atlanta, Georgia, United States of America. Mabbott NA; The Roslin Institute & Royal (Dick) School of Veterinary Sciences, University of Edinburgh, United Kingdom.
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PLoS pathogens [PLoS Pathog] 2016 Dec 14; Vol. 12 (12), pp. e1006075. Date of Electronic Publication: 2016 Dec 14 (Print Publication: 2016).
An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells.
Autorzy:
Powell JJ; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Thomas-McKay E; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Thoree V; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Robertson J; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Hewitt RE; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Skepper JN; Cambridge Advanced Imaging Centre, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK. Brown A; Institute for Materials Research, SPEME, University of Leeds, Leeds LS2 9JT, UK. Hernandez-Garrido JC; Departamento de Ciencia de los Materiales e Ingenieria Metalúrgica y Química Inorganica, Facultad de Ciencias, Universidad de Cádiz, Campus Universitario Rio San Pedro, Puerto Real (Cádiz) 11.510, Spain. Midgley PA; Department of Materials Science and Metallurgy, University of Cambridge, 27 Charles Babbage Road, Cambridge CB3 0FS, UK. Gomez-Morilla I; Technische Universitaet Dresden, Fakultaet Maschinenwesen, Institut fuer Stroemungsmechanik, Dresden 01062, Germany. Grime GW; Ion Beam Centre, Advanced Technology Institute, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK. Kirkby KJ; 1] Ion Beam Centre, Advanced Technology Institute, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK [2] Institute of Cancer Sciences, The University of Manchester, 27 Palatine Road, Withington, Manchester M20 3LJ, UK. Mabbott NA; The Roslin Institute and Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. DonaldsonDS; The Roslin Institute and Royal (Dick) School of Veterinary Sciences, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. Williams IR; Department of Pathology, Emory University School of Medicine, 615 Michael Street, Atlanta, Georgia 30322, USA. Rios D; Department of Pathology, Emory University School of Medicine, 615 Michael Street, Atlanta, Georgia 30322, USA. Girardin SE; Department of Laboratory Medicine and Pathobiology, 1 King's College Circle, Toronto M5S 1A8, Canada. Haas CT; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Bruggraber SF; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK. Laman JD; 1] Department of Immunology, Erasmus MC, University Medical Centre and MS Centre ErasMS, PO Box 2040, Rotterdam 3000 CA, The Netherlands [2] Department of Neuroscience, Section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Tanriver Y; Department of Internal Medicine IV and Institute of Medical Microbiology and Hygiene, University Medical Center, Freiburg 79106, Germany. Lombardi G; Immunoregulation Laboratory, MRC Centre for Transplantation, King's College London, Guys' Hospital, London SE1 9RT, UK. Lechler R; Immunoregulation Laboratory, MRC Centre for Transplantation, King's College London, Guys' Hospital, London SE1 9RT, UK. Thompson RP; 1] Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK [2] Royal College of Physicians, 11 St Andrews Place, Regent's Park, London NW1 4LE, UK. Pele LC; Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK.
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Źródło:
Nature nanotechnology [Nat Nanotechnol] 2015 Apr; Vol. 10 (4), pp. 361-9. Date of Electronic Publication: 2015 Mar 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration.
Autorzy:
Sauter KA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Pridans C; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Sehgal A; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Bain CC; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, Scotland, United Kingdom. Scott C; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, Scotland, United Kingdom. Moffat L; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Rojo R; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Stutchfield BM; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, Midlothian, Scotland, United Kingdom. Davies CL; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. DonaldsonDS; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Renault K; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. McColl BW; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Mowat AM; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, Scotland, United Kingdom. Serrels A; Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, Midlothian, Scotland, United Kingdom. Frame MC; Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, Midlothian, Scotland, United Kingdom. Mabbott NA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom. Hume DA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom.
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Źródło:
PloS one [PLoS One] 2014 Aug 19; Vol. 9 (8), pp. e105429. Date of Electronic Publication: 2014 Aug 19 (Print Publication: 2014).
Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations.
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