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Wyszukujesz frazę ""Dopamine Antagonists"" wg kryterium: Temat


Tytuł:
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Autorzy:
Xue Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Zhang Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Zhao R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Liu X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Grützmann K; Core Unit for Molecular Tumour Diagnostics (CMTD), National Center for Tumour Diseases (NCT) Dresden, Dresden, Germany.; Institute for Medical Informatics and Biometry, Medical Faculty, TU Dresden, Dresden, Germany.
Klink B; Department of Genetics, Laboratoire National de Santé, Dudelange, Luxembourg.
Zhang X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Wang S; Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY, 10016, USA.
Zhao W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Sun Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Han M; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Wang X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hu Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Liu X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Yang N; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Qiu C; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.; Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, China.
Li W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Huang B; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Li X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China.
Bjerkvig R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, 5009, Norway.
Wang J; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China. .; Jinan Microecological Biomedicine Shandong Laboratory and Shandong Key Laboratory of Brain Function Remodeling, Jinan, China. .; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, 5009, Norway. .
Zhou W; Department of Blood Transfusion, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jan 22; Vol. 43 (1), pp. 25. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioma*
Dopamine Antagonists*/metabolism
Dopamine Antagonists*/pharmacology
Proto-Oncogene Proteins c-myc*/drug effects
Proto-Oncogene Proteins c-myc*/metabolism
Animals ; Humans ; Mice ; Brain ; CCAAT-Enhancer-Binding Proteins/drug effects ; CCAAT-Enhancer-Binding Proteins/metabolism ; Dopamine ; Mice, Nude ; Multigene Family ; Receptors, Dopamine D1/antagonists & inhibitors ; Ubiquitin-Protein Ligases/drug effects ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł:
Pharmacological management of neurocognitive impairment in schizophrenia: A narrative review.
Autorzy:
Arsenault‐Mehta, Kyle (AUTHOR)
Hochman‐Bérard, Mario (AUTHOR)
Johnson, Alexander (AUTHOR)
Semenova, Dar'ya (AUTHOR)
Nguyen, Bea (AUTHOR)
Willis, Jessie (AUTHOR)
Mouravska, Natalia (AUTHOR)
Joober, Ridha (AUTHOR)
Zhand, Naista (AUTHOR)
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Źródło:
Neuropsychopharmacology Reports. Mar2024, Vol. 44 Issue 1, p2-16. 15p.
Czasopismo naukowe
Tytuł:
Effects of chronic haloperidol treatment on the expression of fear memory and fear memory extinction in the cued fear‐conditioned rats.
Autorzy:
Enomoto, Kosuke (AUTHOR)
Shibata, Kazuro (AUTHOR)
Muraoka, Hiroyuki (AUTHOR)
Kawano, Masahiko (AUTHOR)
Inada, Ken (AUTHOR)
Ishigooka, Jun (AUTHOR)
Nishimura, Katsuji (AUTHOR)
Oshibuchi, Hidehiro (AUTHOR)
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Źródło:
Neuropsychopharmacology Reports. Mar2024, Vol. 44 Issue 1, p197-205. 9p.
Czasopismo naukowe
Tytuł:
Integrative Roles of Dopamine Pathway and Calcium Channels Reveal a Link between Schizophrenia and Opioid Use Disorder.
Autorzy:
Thiagarajan SK; Department of Mechatronics and Biomedical Engineering, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
Mok SY; Department of Mechatronics and Biomedical Engineering, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
Ogawa S; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Malaysia.
Parhar IS; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Malaysia.
Tang PY; Department of Mechatronics and Biomedical Engineering, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 17; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Channels*/metabolism
Dopamine*/metabolism
Dopaminergic Neurons*/drug effects
Dopaminergic Neurons*/metabolism
Morphine*/administration & dosage
Morphine*/pharmacology
Opioid-Related Disorders*/metabolism
Schizophrenia*/metabolism
Domperidone*/administration & dosage
Domperidone*/pharmacology
Dopamine Antagonists*/administration & dosage
Dopamine Antagonists*/pharmacology
Animals ; Zebrafish ; Locomotion/drug effects ; Metabolic Networks and Pathways
Czasopismo naukowe
Tytuł:
A Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of the Dopamine Receptor Antagonist LE300 and Its N-methyl Metabolite in Plasma: Application to a Pharmacokinetic Study.
Autorzy:
Hefnawy MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.; Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Attwa MW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alzamil AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
El-Gendy MA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Jardan YAB; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
El-Gamal AA; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 06; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*/methods
Dopamine Antagonists*
Rats ; Animals ; Chromatography, Liquid/methods ; Chromatography, High Pressure Liquid/methods ; Rats, Wistar ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
From Selye's and Szabo's Cysteamine-Duodenal Ulcer in Rats to Dopamine in the Stomach: Therapy Significance and Possibilities.
Autorzy:
Sikiric, Predrag (AUTHOR)
Boban Blagaic, Alenka (AUTHOR)
Krezic, Ivan (AUTHOR)
Zizek, Helena (AUTHOR)
Kalogjera, Luka (AUTHOR)
Smoday, Ivan Maria (AUTHOR)
Vukovic, Vlasta (AUTHOR)
Oroz, Katarina (AUTHOR)
Chiddenton, Helen Marie (AUTHOR)
Buric, Sara (AUTHOR)
Antunovic, Marko (AUTHOR)
Gojkovic, Slaven (AUTHOR)
Strbe, Sanja (AUTHOR)
Skocic, Milena (AUTHOR)
Sikiric, Suncana (AUTHOR)
Milavic, Marija (AUTHOR)
Beketic Oreskovic, Lidija (AUTHOR)
Kokot, Antonio (AUTHOR)
Koprivanac, Antun (AUTHOR)
Dobric, Ivan (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Dec2023, Vol. 16 Issue 12, p1699. 14p.
Czasopismo naukowe
Tytuł:
SCH23390 and a humanized anti-cocaine mAb decrease the latency to cocaine-induced reinstatement of lever pressing behavior in rats that self-administer cocaine.
Autorzy:
Zinani DB; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Desai JN; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Norman AB; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 04; Vol. 13 (1), pp. 14566. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Benzazepines*
Cocaine*/pharmacology
Male ; Animals ; Rats ; Biological Assay ; Dopamine Antagonists
Czasopismo naukowe
Tytuł:
Structure-Activity Relationship Studies on 6-Chloro-1-phenylbenzazepines Leads to the Identification of a New Dopamine D1 Receptor Antagonist.
Autorzy:
Giri R; Department of Chemistry, Hunter College, City University of New York, 695 Park Avenue, New York, NY 10065, USA.; Program in Chemistry, CUNY Graduate Center, 365 5th Avenue, New York, NY 10016, USA.
Namballa HK; Department of Chemistry, Hunter College, City University of New York, 695 Park Avenue, New York, NY 10065, USA.
Emogaje V; Department of Chemistry, Hunter College, City University of New York, 695 Park Avenue, New York, NY 10065, USA.
Harding WW; Department of Chemistry, Hunter College, City University of New York, 695 Park Avenue, New York, NY 10065, USA.; Program in Chemistry, CUNY Graduate Center, 365 5th Avenue, New York, NY 10016, USA.; Program in Biochemistry, CUNY Graduate Center, 365 5th Avenue, New York, NY 10016, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 11; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Dopamine D1*
Amides*
Benzazepines/pharmacology ; Dopamine Antagonists ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis.
Autorzy:
Mohamad SA; Department of Pharmaceutics, Faculty of Pharmacy, Deraya University, Minia, Egypt.
Safwat MA; Department of Pharmaceutics, Faculty of Pharmacy, South Valley University, Qena, Egypt.
Elrehany M; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt.; Department of Biochemistry, Faculty of Medicine, Minia University, Minia, Egypt.
Maher SA; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt.
Badawi AM; Department of Otorhinolaryngology, Faculty of Medicine, Minia University, Minia, Egypt.
Mansour HF; Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, Egypt.
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Źródło:
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 229-239.
Typ publikacji:
Journal Article
MeSH Terms:
Emulsions*
Surface-Active Agents*
Dopamine Antagonists/*administration & dosage
Histamine H1 Antagonists, Non-Sedating/*administration & dosage
Loratadine/*administration & dosage
Nasal Mucosa/*drug effects
Rhinitis, Allergic/*metabolism
Sulpiride/*administration & dosage
Administration, Intranasal ; Animals ; Calorimetry, Differential Scanning ; Disease Models, Animal ; Dopamine Antagonists/pharmacology ; Drug Combinations ; Drug Liberation ; Glycerol ; Histamine H1 Antagonists, Non-Sedating/pharmacology ; In Vitro Techniques ; Interleukin-1/metabolism ; Lecithins ; Loratadine/pharmacology ; Nanostructures ; Nasal Mucosa/metabolism ; Olive Oil ; Ovalbumin ; Paranasal Sinuses/drug effects ; Paranasal Sinuses/metabolism ; Polysorbates ; Rabbits ; Rhinitis, Allergic/chemically induced ; Sodium Cholate ; Glycine max ; Spectroscopy, Fourier Transform Infrared ; Sulpiride/pharmacology ; Transforming Growth Factor beta/drug effects ; Transforming Growth Factor beta/metabolism ; Tumor Necrosis Factor-alpha/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Energizing effects of bupropion on effortful behaviors in mice under positive and negative test conditions: modulation of DARPP-32 phosphorylation patterns.
Autorzy:
Carratalá-Ros C; Àrea de Psicobiologia, Universitat Jaume I, Campus de Riu Sec, 12071, Castelló, Spain.
Olivares-García R; Àrea de Psicobiologia, Universitat Jaume I, Campus de Riu Sec, 12071, Castelló, Spain.
Martínez-Verdú A; Àrea de Psicobiologia, Universitat Jaume I, Campus de Riu Sec, 12071, Castelló, Spain.
Arias-Sandoval E; Àrea de Psicobiologia, Universitat Jaume I, Campus de Riu Sec, 12071, Castelló, Spain.
Salamone JD; Behavioral Neuroscience Division, University of Connecticut, Storrs, CT, 06269-1020, USA.
Correa M; Àrea de Psicobiologia, Universitat Jaume I, Campus de Riu Sec, 12071, Castelló, Spain. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2021 Dec; Vol. 238 (12), pp. 3357-3373. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Bupropion*/pharmacology
Dopamine Antagonists*
Animals ; Choice Behavior ; Male ; Mice ; Phosphorylation ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response.
Autorzy:
Matteoni S; Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS - Regina Elena National Cancer Institute, 00144, Rome, Italy.
Matarrese P; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, 00161, Rome, Italy.
Ascione B; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, 00161, Rome, Italy.
Ricci-Vitiani L; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161, Rome, Italy.
Pallini R; Institute of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University School of Medicine, 00168, Rome, Italy.
Villani V; Neuro-Oncology, IRCCS - Regina Elena National Cancer Institute, 00144, Rome, Italy.
Pace A; Neuro-Oncology, IRCCS - Regina Elena National Cancer Institute, 00144, Rome, Italy.
Paggi MG; Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS - Regina Elena National Cancer Institute, 00144, Rome, Italy. .
Abbruzzese C; Cellular Networks and Molecular Therapeutic Targets, Proteomics Unit, IRCCS - Regina Elena National Cancer Institute, 00144, Rome, Italy. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2021 Nov 05; Vol. 40 (1), pp. 347. Date of Electronic Publication: 2021 Nov 05.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*genetics
Chlorpromazine/*therapeutic use
Dopamine Antagonists/*therapeutic use
Endoplasmic Reticulum Stress/*drug effects
Glioblastoma/*drug therapy
Unfolded Protein Response/*drug effects
Chlorpromazine/pharmacology ; Dopamine Antagonists/pharmacology ; Glioblastoma/mortality ; Humans ; Survival Analysis
Czasopismo naukowe
Tytuł:
Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases.
Autorzy:
Załuski, Michał (AUTHOR)
Karcz, Tadeusz (AUTHOR)
Drabczyńska, Anna (AUTHOR)
Vielmuth, Christin (AUTHOR)
Olejarz-Maciej, Agnieszka (AUTHOR)
Głuch-Lutwin, Monika (AUTHOR)
Mordyl, Barbara (AUTHOR)
Siwek, Agata (AUTHOR)
Satała, Grzegorz (AUTHOR)
Müller, Christa E. (AUTHOR)
Kieć-Kononowicz, Katarzyna (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Jul2023, Vol. 13 Issue 7, p1079. 23p.
Czasopismo naukowe
Tytuł:
Development and Characterization of Novel Selective, Non-Basic Dopamine D 2 Receptor Antagonists for the Treatment of Schizophrenia.
Autorzy:
Stępnicki, Piotr (AUTHOR)
Wośko, Sylwia (AUTHOR)
Bartyzel, Agata (AUTHOR)
Zięba, Agata (AUTHOR)
Bartuzi, Damian (AUTHOR)
Szałaj, Klaudia (AUTHOR)
Wróbel, Tomasz M. (AUTHOR)
Fornal, Emilia (AUTHOR)
Carlsson, Jens (AUTHOR)
Kędzierska, Ewa (AUTHOR)
Poleszak, Ewa (AUTHOR)
Castro, Marián (AUTHOR)
Kaczor, Agnieszka A. (AUTHOR)
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Źródło:
Molecules. May2023, Vol. 28 Issue 10, p4211. 28p.
Czasopismo naukowe
Tytuł:
Dopamine D 1 Agonists: First Potential Treatment for Late-Stage Parkinson's Disease.
Autorzy:
Lewis, Mechelle M. (AUTHOR)
Van Scoy, Lauren J. (AUTHOR)
De Jesus, Sol (AUTHOR)
Hakun, Jonathan G. (AUTHOR)
Eslinger, Paul J. (AUTHOR)
Fernandez-Mendoza, Julio (AUTHOR)
Kong, Lan (AUTHOR)
Yang, Yang (AUTHOR)
Snyder, Bethany L. (AUTHOR)
Loktionova, Natalia (AUTHOR)
Duvvuri, Sridhar (AUTHOR)
Gray, David L. (AUTHOR)
Huang, Xuemei (AUTHOR)
Mailman, Richard B. (AUTHOR)
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Źródło:
Biomolecules (2218-273X). May2023, Vol. 13 Issue 5, p829. 23p.
Czasopismo naukowe
Tytuł:
A first-in-human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers.
Autorzy:
Sjöberg F; Clinical Trials Consultants AB, Uppsala, Sweden.; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Waters S; Integrative Research Laboratories AB, Gothenburg, Sweden.
Löfberg B; Integrative Research Laboratories AB, Gothenburg, Sweden.
Sonesson C; Integrative Research Laboratories AB, Gothenburg, Sweden.
Waters N; Integrative Research Laboratories AB, Gothenburg, Sweden.
Tedroff J; Integrative Research Laboratories AB, Gothenburg, Sweden.; Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2021 May; Vol. 9 (3), pp. e00792.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
MeSH Terms:
Dopamine Antagonists/*administration & dosage
Phenyl Ethers/*administration & dosage
Propylamines/*administration & dosage
Receptors, Dopamine D3/*antagonists & inhibitors
Administration, Oral ; Adolescent ; Adult ; Biological Availability ; Dopamine Antagonists/adverse effects ; Dopamine Antagonists/pharmacokinetics ; Dose-Response Relationship, Drug ; Double-Blind Method ; Fasting/metabolism ; Food-Drug Interactions ; Half-Life ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Phenyl Ethers/adverse effects ; Phenyl Ethers/pharmacokinetics ; Propylamines/adverse effects ; Propylamines/pharmacokinetics ; Young Adult
Czasopismo naukowe
Tytuł:
Managing and treating Sydenham chorea: A systematic review.
Autorzy:
Tariq S; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Niaz F; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Waseem S; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Shaikh TG; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Ahmed SH; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Irfan M; Department of Internal Medicine, Wellstar Health System Spalding Hospital Griffin, Georgia, USA.
Nashwan AJ; Hamad Medical Corporation, Doha, Qatar.
Ullah I; Kabir Medical College, Gandhara University, Peshawar Khyber Pakhtunkhkwa, Pakistan.
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Źródło:
Brain and behavior [Brain Behav] 2023 Jun; Vol. 13 (6), pp. e3035. Date of Electronic Publication: 2023 May 07.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Chorea*/diagnosis
Chorea*/drug therapy
Female ; Humans ; Male ; Anticonvulsants/therapeutic use ; Valproic Acid/therapeutic use ; Haloperidol ; Dopamine Antagonists
Czasopismo naukowe
Tytuł:
Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans.
Autorzy:
Tomasi D; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA. .
Manza P; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Logan J; Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, NY, New York, USA.
Shokri-Kojori E; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Yonga MV; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Kroll D; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Feldman D; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
McPherson K; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Biesecker C; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Dennis E; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Johnson A; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Yuan K; School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China.
Wang WT; Radiology and Imaging Sciences, Clinical Center, National Institute of Health, Bethesda, MD, USA.
Butman JA; Radiology and Imaging Sciences, Clinical Center, National Institute of Health, Bethesda, MD, USA.
Wang GJ; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Volkow ND; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
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Źródło:
Communications biology [Commun Biol] 2023 Feb 10; Vol. 6 (1), pp. 166. Date of Electronic Publication: 2023 Feb 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Methylphenidate*/pharmacology
Attention Deficit Disorder with Hyperactivity*
Humans ; Dopamine/metabolism ; Raclopride/metabolism ; Raclopride/pharmacology ; Raclopride/therapeutic use ; Brain/metabolism ; Dopamine Antagonists/metabolism ; Dopamine Antagonists/pharmacology ; Dopamine Antagonists/therapeutic use
Czasopismo naukowe
Tytuł:
Canonical and Non-Canonical Antipsychotics' Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia.
Autorzy:
de Bartolomeis, Andrea (AUTHOR)
Ciccarelli, Mariateresa (AUTHOR)
De Simone, Giuseppe (AUTHOR)
Mazza, Benedetta (AUTHOR)
Barone, Annarita (AUTHOR)
Vellucci, Licia (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 6, p5945. 57p.
Czasopismo naukowe
Tytuł:
Quantitative analysis of fluorescent ligand binding to dopamine D 3 receptors using live-cell microscopy.
Autorzy:
Allikalt A; Institute of Chemistry, University of Tartu, Estonia.; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander University Erlangen-Nürnberg, Germany.
Laasfeld T; Institute of Chemistry, University of Tartu, Estonia.
Ilisson M; Institute of Chemistry, University of Tartu, Estonia.
Kopanchuk S; Institute of Chemistry, University of Tartu, Estonia.
Rinken A; Institute of Chemistry, University of Tartu, Estonia.
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Źródło:
The FEBS journal [FEBS J] 2021 Mar; Vol. 288 (5), pp. 1514-1532. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay*
Software*
Carbocyanines/*chemistry
Dopamine Antagonists/*pharmacology
Receptors, Dopamine/*metabolism
Spiperone/*analogs & derivatives
Dopamine/metabolism ; Dopamine/pharmacology ; Dopamine Antagonists/chemical synthesis ; HEK293 Cells ; Humans ; Image Processing, Computer-Assisted/methods ; Image Processing, Computer-Assisted/statistics & numerical data ; Kinetics ; Ligands ; Machine Learning ; Microscopy, Fluorescence/methods ; Microscopy, Fluorescence/statistics & numerical data ; Protein Binding ; Spiperone/chemistry
Czasopismo naukowe
Tytuł:
Neural bases for attenuation of morphine withdrawal by Heantos-4: role of l-tetrahydropalmatine.
Autorzy:
Ahn S; Department of Psychiatry, University of British Columbia, Vancouver, V6T 2A1, Canada.
Nesbit MO; Department of Psychiatry, University of British Columbia, Vancouver, V6T 2A1, Canada.
Zou H; Department of Psychiatry, University of British Columbia, Vancouver, V6T 2A1, Canada.
Vacca G; Department of Psychiatry, University of British Columbia, Vancouver, V6T 2A1, Canada.
Axerio-Cilies P; Department of Psychiatry, University of British Columbia, Vancouver, V6T 2A1, Canada.
Van Sung T; Institute of Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Phillips AG; Department of Psychiatry, University of British Columbia, Vancouver, V6T 2A1, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 04; Vol. 10 (1), pp. 21275. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Berberine Alkaloids/*therapeutic use
Dopamine Antagonists/*therapeutic use
Nucleus Accumbens/*drug effects
Plant Extracts/*therapeutic use
Substance Withdrawal Syndrome/*drug therapy
Analgesics, Opioid/adverse effects ; Animals ; Berberine Alkaloids/metabolism ; Berberine Alkaloids/pharmacology ; Dopamine/metabolism ; Dopamine Antagonists/metabolism ; Dopamine Antagonists/pharmacology ; Drug Evaluation, Preclinical ; Male ; Morphine/adverse effects ; Nucleus Accumbens/metabolism ; Phytotherapy ; Plant Extracts/metabolism ; Plant Extracts/pharmacology ; Quinpirole ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Domperidone-Induced Secondary Parkinsonism: A Rare Case Report with Combination Proton Pump Inhibitor.
Autorzy:
Bhowmik S; Department of Neurology, ABVIMS and Dr. RML Hospital, New Delhi, India.
Anand KS; Department of Neurology, ABVIMS and Dr. RML Hospital, New Delhi, India.
Bhattacharya A; Department of Neurology, ABVIMS and Dr. RML Hospital, New Delhi, India.
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Źródło:
Neurology India [Neurol India] 2023 Mar-Apr; Vol. 71 (2), pp. 334-335.
Typ publikacji:
Case Reports; Letter
MeSH Terms:
Domperidone*/adverse effects
Parkinson Disease, Secondary*
Humans ; Proton Pump Inhibitors/adverse effects ; Dopamine Antagonists
Raport
Tytuł:
Pallidal deep brain stimulation for tardive dystonia: meta-analysis of clinical outcomes.
Autorzy:
Grabel M; Department of Environmental Health Division of Biostatistics and Bioinformatics, University of Cincinnati College of Medicine, Kettering Lab Building, Room 112, 160 Panzeca Way, Cincinnati, OH, 45267-0056, USA. .
Merola A; Department of Neurology, Ohio State University Wexner Medical Center, Columbus, OH, USA.
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2023 Mar; Vol. 44 (3), pp. 827-833. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Meta-Analysis; Journal Article; Review; Retracted Publication
MeSH Terms:
Tardive Dyskinesia*/therapy
Deep Brain Stimulation*/methods
Dystonic Disorders*/therapy
Dystonia*
Humans ; Globus Pallidus ; Treatment Outcome ; Dopamine Antagonists
Czasopismo naukowe
Tytuł:
Risk of Adverse Events Associated with Domperidone and Metoclopramide in Gastroparesis: Systematic Review and Meta-analysis.
Autorzy:
Junqueira DR; Evidera, a part of Thermo Fisher Scientific, Montreal, QC, Canada.
Bennett D; Takeda Development Center Americas, Inc., 35 Landsdowne St, Cambridge, MA, 02139, USA. .; University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. .
Huh SY; Takeda Development Center Americas, Inc., 35 Landsdowne St, Cambridge, MA, 02139, USA.; Ironwood Pharmaceuticals, Boston, MA, USA.
Fahrbach K; Evidera, a part of Thermo Fisher Scientific, Waltham, MA, USA.
Neupane B; Evidera, a part of Thermo Fisher Scientific, Montreal, QC, Canada.
Betts M; Evidera, a part of Thermo Fisher Scientific, Waltham, MA, USA.
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Źródło:
Drugs in R&D [Drugs R D] 2023 Mar; Vol. 23 (1), pp. 1-20. Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:
Meta-Analysis; Systematic Review
MeSH Terms:
Domperidone*/adverse effects
Gastroparesis*/chemically induced
Gastroparesis*/drug therapy
Adult ; Child ; Humans ; Metoclopramide/adverse effects ; Dopamine Antagonists/adverse effects
Raport
Tytuł:
Women's experiences with using domperidone as a galactagogue to increase breast milk supply: an australian cross-sectional survey.
Autorzy:
McBride GM; Adelaide Medical School, Robinson Research Institute, University of Adelaide , Adelaide, Australia.; SAHMRI Women and Kids, South Australian Health and Medical Research Institute, Adelaide, Australia.
Stevenson R; Adelaide Medical School, Robinson Research Institute, University of Adelaide , Adelaide, Australia.
Zizzo G; Adelaide Medical School, Robinson Research Institute, University of Adelaide , Adelaide, Australia.
Rumbold AR; Adelaide Medical School, Robinson Research Institute, University of Adelaide , Adelaide, Australia.; SAHMRI Women and Kids, South Australian Health and Medical Research Institute, Adelaide, Australia.
Amir LH; Judith Lumley Centre, La Trobe University, Melbourne, Australia.; Breastfeeding Service, Royal Women's Hospital, Parkville, Australia.
Keir A; Adelaide Medical School, Robinson Research Institute, University of Adelaide , Adelaide, Australia.; SAHMRI Women and Kids, South Australian Health and Medical Research Institute, Adelaide, Australia.
Grzeskowiak LE; Adelaide Medical School, Robinson Research Institute, University of Adelaide , Adelaide, Australia.; SAHMRI Women and Kids, South Australian Health and Medical Research Institute, Adelaide, Australia.; SA Pharmacy, SA Health, Adelaide, Australia.; College of Medicine and Public, Flinders Health and Medical Research Institute Flinders University, GPO Box 2100, SA, 5001, Adelaide, Australia.
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Źródło:
International breastfeeding journal [Int Breastfeed J] 2023 Feb 07; Vol. 18 (1), pp. 11. Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Domperidone*/adverse effects
Galactogogues*/adverse effects
Infant, Newborn ; Female ; Humans ; Pregnancy ; Milk, Human ; Breast Feeding ; Cross-Sectional Studies ; Dopamine Antagonists/adverse effects ; Lactation ; Cesarean Section ; Australia
Czasopismo naukowe
Tytuł:
The antipsychotic drug sulpiride in the ventral pallidum paradoxically impairs learning and induces place preference.
Autorzy:
Dusa, Daniella (AUTHOR)
Ollmann, Tamás (AUTHOR)
Kállai, Veronika (AUTHOR)
Lénárd, László (AUTHOR)
Kertes, Erika (AUTHOR)
Berta, Beáta (AUTHOR)
Szabó, Ádám (AUTHOR)
László, Kristóf (AUTHOR)
Gálosi, Rita (AUTHOR)
Zagoracz, Olga (AUTHOR)
Karádi, Zoltán (AUTHOR)
Péczely, László (AUTHOR)
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Źródło:
Scientific Reports. 11/10/2022, Vol. 12 Issue 1, p1-14. 14p.
Czasopismo naukowe
Tytuł:
Perphenazine Attenuates the Pro-Inflammatory Responses in Mouse Models of Th2-Type Allergic Dermatitis.
Autorzy:
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 May 03; Vol. 21 (9). Date of Electronic Publication: 2020 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Dermatitis, Allergic Contact/*drug therapy
Dopamine Antagonists/*therapeutic use
Perphenazine/*therapeutic use
Animals ; Cytokines/metabolism ; Dermatitis, Allergic Contact/etiology ; Dopamine Antagonists/pharmacology ; Immunoglobulin G/metabolism ; Mast Cells/drug effects ; Mast Cells/immunology ; Mice ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Oxazolone/toxicity ; Perphenazine/pharmacology ; Tetradecanoylphorbol Acetate/toxicity ; Th2 Cells/drug effects ; Th2 Cells/immunology
Czasopismo naukowe
Tytuł:
A randomized, double-blind, placebo controlled, phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of LB-102, a selective dopamine D2/3/5-HT7 inhibitor.
Autorzy:
Biernat, Lukasz (AUTHOR)
Grattan, Vincent T. (AUTHOR)
Hixon, Mark S. (AUTHOR)
Prensky, Zachary (AUTHOR)
Vaino, Andrew R. (AUTHOR)
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Źródło:
Psychopharmacology. Sep2022, Vol. 239 Issue 9, p3009-3018. 10p. 6 Charts, 2 Graphs.
Czasopismo naukowe
Tytuł:
Prevention of diet restriction induced hyperactivity but not body-weight reduction in rats co-treated with tryptophan: relationship with striatal serotonin and dopamine metabolism and serotonin-1A auto-receptor expression.
Autorzy:
Saeed, Raheel (AUTHOR)
Mahmood, Khalid (AUTHOR)
Ali, Sadia Basharat (AUTHOR)
Haleem, Darakhshan Jabeen (AUTHOR)
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Źródło:
Nutritional Neuroscience. Aug2022, Vol. 25 Issue 8, p1764-1773. 10p. 1 Chart, 5 Graphs.
Czasopismo naukowe
Tytuł:
Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism.
Autorzy:
Eissa, Nermin (AUTHOR)
Venkatachalam, Karthikkumar (AUTHOR)
Jayaprakash, Petrilla (AUTHOR)
Yuvaraju, Priya (AUTHOR)
Falkenstein, Markus (AUTHOR)
Stark, Holger (AUTHOR)
Sadek, Bassem (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Aug2022, Vol. 15 Issue 8, p929-929. 19p.
Czasopismo naukowe
Tytuł:
Pharmacoencephalographic Assessment of Antiphyschotic Agents' Effect Dose-Dependency in Rats.
Autorzy:
Sysoev, Yu. I. (AUTHOR)
Shits, D. D. (AUTHOR)
Puchik, M. M. (AUTHOR)
Knyazeva, I. S. (AUTHOR)
Korelov, M. S. (AUTHOR)
Prikhodko, V. A. (AUTHOR)
Titovich, I. A. (AUTHOR)
Selizarova, N. O. (AUTHOR)
Okovityi, S. V. (AUTHOR)
Pokaż więcej
Źródło:
Journal of Evolutionary Biochemistry & Physiology. Nov2023, Vol. 59 Issue 6, p2153-2167. 15p.
Czasopismo naukowe
Tytuł:
Dopaminergic antagonists inhibit bile chemotaxis of adult Clonorchis sinensis and its egg production.
Autorzy:
Dai F; Department of Medical Environmental Biology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Department of Parasitology, School of Biology and Basic Medical Sciences, Medical College, Soochow University, Suzhou, Jiangsu, PR China.
Song JH; Department of Pharmacology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Hong YP; Department of Preventive Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Bai X; Department of Medical Environmental Biology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.; Clinical Medicine Laboratory, Affiliated Hospital of Binzhou Medical University, Binzhou, Shandong, PR China.
Sohn WM; Department of Parasitology and Institute of Health Sciences, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Hong SJ; Department of Medical Environmental Biology, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Mar 30; Vol. 14 (3), pp. e0008220. Date of Electronic Publication: 2020 Mar 30 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anthelmintics/*pharmacology
Antipsychotic Agents/*pharmacology
Chemotaxis/*drug effects
Clonorchis sinensis/*drug effects
Clonorchis sinensis/*physiology
Dopamine Antagonists/*pharmacology
Animals ; Anthelmintics/administration & dosage ; Antipsychotic Agents/administration & dosage ; Bile/metabolism ; Chemotactic Factors/metabolism ; Cholic Acid/metabolism ; Clonorchiasis/drug therapy ; Disease Models, Animal ; Dopamine Antagonists/administration & dosage ; Female ; Fertility/drug effects ; Humans ; Lithocholic Acid/metabolism ; Rabbits ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Tytuł:
A quantum chemical approach representing a new perspective concerning agonist and antagonist drugs in the context of schizophrenia and Parkinson's disease.
Autorzy:
Martínez A; Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Circuito Exterior S. N., Ciudad Universitaria, CDMX, México.; Departamento de Química, División de Ciencias Básicas e Ingeniería, Universidad Autónoma Metropolitana-Iztapalapa, CDMX, México.
Ibarra IA; Laboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, CDMX, Mexico.
Vargas R; Departamento de Química, División de Ciencias Básicas e Ingeniería, Universidad Autónoma Metropolitana-Iztapalapa, CDMX, México.
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Źródło:
PloS one [PLoS One] 2019 Dec 12; Vol. 14 (12), pp. e0224691. Date of Electronic Publication: 2019 Dec 12 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Models, Chemical*
Quantum Theory*
Antipsychotic Agents/*chemistry
Dopamine Agonists/*chemistry
Dopamine Antagonists/*chemistry
Parkinson Disease/*drug therapy
Schizophrenia/*drug therapy
Antipsychotic Agents/therapeutic use ; Dopamine Agonists/therapeutic use ; Dopamine Antagonists/therapeutic use ; Humans ; Molecular Structure
Czasopismo naukowe
Tytuł:
Inclusion of enclosed hydration effects in the binding free energy estimation of dopamine D3 receptor complexes.
Autorzy:
Pal RK; Department of Chemistry, Brooklyn College, 2900 Bedford Avenue, Brooklyn, NY 11210, United States of America.; PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.
Gadhiya S; PhD Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; Department of Chemistry, Hunter College, 695 Park Avenue, NY 10065, United States of America.
Ramsey S; PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; Department of Chemistry, Lehman College, 250 Bedford Park Blvd. West, Bronx, NY 10468, United States of America.
Cordone P; PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; Department of Chemistry, Hunter College, 695 Park Avenue, NY 10065, United States of America.
Wickstrom L; Department of Science, Borough of Manhattan Community College, 199 Chambers Street, New York, NY 10007, United States of America.
Harding WW; PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; PhD Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; Department of Chemistry, Hunter College, 695 Park Avenue, NY 10065, United States of America.
Kurtzman T; PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; PhD Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; Department of Chemistry, Lehman College, 250 Bedford Park Blvd. West, Bronx, NY 10468, United States of America.
Gallicchio E; Department of Chemistry, Brooklyn College, 2900 Bedford Avenue, Brooklyn, NY 11210, United States of America.; PhD Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.; PhD Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Sep 30; Vol. 14 (9), pp. e0222902. Date of Electronic Publication: 2019 Sep 30 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Amino Acids/*chemistry
Berberine/*analogs & derivatives
Dopamine Antagonists/*chemistry
Receptors, Dopamine D3/*chemistry
Water/*chemistry
Amino Acids/metabolism ; Berberine/chemical synthesis ; Berberine/chemistry ; Binding Sites ; Dopamine Antagonists/chemical synthesis ; Humans ; Ligands ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Interaction Domains and Motifs ; Receptors, Dopamine D3/antagonists & inhibitors ; Receptors, Dopamine D3/metabolism ; Thermodynamics ; Water/metabolism
Czasopismo naukowe
Tytuł:
Dopamine receptor antagonists as potential therapeutic agents for ADPKD.
Autorzy:
Paul P; Center for Cell Dynamics, Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.; Stowers Institute for Medical Research, Kansas City, MO, United States.
Ramachandran S; Center for Cell Dynamics, Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Xia S; Center for Cell Dynamics, Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.; Stowers Institute for Medical Research, Kansas City, MO, United States.; Division of Neonatology, Children's Mercy Hospital, Kansas City, MO, United States.
Unruh JR; Stowers Institute for Medical Research, Kansas City, MO, United States.
Conkright-Fincham J; Stowers Institute for Medical Research, Kansas City, MO, United States.
Li R; Center for Cell Dynamics, Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.; Stowers Institute for Medical Research, Kansas City, MO, United States.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, United States.
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Źródło:
PloS one [PLoS One] 2019 May 06; Vol. 14 (5), pp. e0216220. Date of Electronic Publication: 2019 May 06 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopamine Antagonists/*therapeutic use
Polycystic Kidney, Autosomal Dominant/*drug therapy
Active Transport, Cell Nucleus ; Animals ; Cell Proliferation/drug effects ; Domperidone/pharmacology ; Domperidone/therapeutic use ; Dopamine Antagonists/pharmacology ; Drug Evaluation, Preclinical/methods ; Epithelial Cells/metabolism ; Histone Deacetylases/metabolism ; Kidney/pathology ; Mice
Czasopismo naukowe
Tytuł:
Biochemical Neuroadaptations in the Rat Striatal Dopaminergic System after Prolonged Exposure to Methamphetamine Self-Administration.
Autorzy:
Jayanthi S; Molecular Neuropsychiatry Research Branch, NIDA Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.
Ladenheim B; Molecular Neuropsychiatry Research Branch, NIDA Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.
Sullivan P; Autonomic Medicine Section, NINDS Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA.
McCoy MT; Molecular Neuropsychiatry Research Branch, NIDA Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.
Krasnova IN; Division for Research Capacity Building, NIGMS, National Institutes of Health, Bethesda, MD 20892, USA.
Goldstein DS; Autonomic Medicine Section, NINDS Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA.
Cadet JL; Molecular Neuropsychiatry Research Branch, NIDA Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 03; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 03.
Typ publikacji:
Journal Article
MeSH Terms:
Methamphetamine*
Animals ; Corpus Striatum/metabolism ; Dopamine/metabolism ; Dopamine Antagonists/pharmacology ; Humans ; Rats ; Rats, Sprague-Dawley ; Self Administration
Czasopismo naukowe
Tytuł:
Critical periods when dopamine controls behavioral responding during Pavlovian learning.
Autorzy:
Lefner MJ; Department of Neuroscience Developmental and Regenerative Biology, Neurosciences Institute, Brain Health Consortium, University of Texas at San Antonio, San Antonio, TX, USA.
Stelly CE; Department of Neuroscience Developmental and Regenerative Biology, Neurosciences Institute, Brain Health Consortium, University of Texas at San Antonio, San Antonio, TX, USA.
Fonzi KM; Department of Neuroscience Developmental and Regenerative Biology, Neurosciences Institute, Brain Health Consortium, University of Texas at San Antonio, San Antonio, TX, USA.
Zurita H; Department of Neuroscience Developmental and Regenerative Biology, Neurosciences Institute, Brain Health Consortium, University of Texas at San Antonio, San Antonio, TX, USA.
Wanat MJ; Department of Neuroscience Developmental and Regenerative Biology, Neurosciences Institute, Brain Health Consortium, University of Texas at San Antonio, San Antonio, TX, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Sep; Vol. 239 (9), pp. 2985-2996. Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
Conditioning, Operant*
Dopamine*/metabolism
Animals ; Conditioning, Classical ; Cues ; Dopamine Antagonists/pharmacology ; Male ; Rats ; Rats, Sprague-Dawley ; Receptors, Dopamine ; Reward
Czasopismo naukowe
Tytuł:
Dopamine D1-like receptor blockade and stimulation decreases operant responding for nicotine and food in male and female rats.
Autorzy:
Chellian R; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Behnood-Rod A; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Wilson R; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Lin K; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
King GW; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Ruppert-Gomez M; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Teter AN; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Febo M; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA.
Bruijnzeel AW; Department of Psychiatry, University of Florida, 1149 Newell Dr., Gainesville, FL, 32611, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 19; Vol. 12 (1), pp. 14131. Date of Electronic Publication: 2022 Aug 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Dopamine*/pharmacology
Nicotine*/pharmacology
Animals ; Benzazepines ; Conditioning, Operant ; Dopamine Agonists/pharmacology ; Dopamine Antagonists/pharmacology ; Dose-Response Relationship, Drug ; Female ; Male ; Rats ; Receptors, Dopamine D1/agonists ; Smoking
Czasopismo naukowe
Tytuł:
Exploratory cross-over, trial of augmented RLS with the dopamine receptor 1/5 antagonist ecopipam D1/D5 antagonist ecopipam for augmented RLS.
Autorzy:
Ondo WG; Methodist Neurological Institute, University of Texas, Houston, TX, USA.; Weill Cornell Medical School, New York, NY, USA.
Olubajo T; Methodist Neurological Institute, University of Texas, Houston, TX, USA.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2022 Aug; Vol. 132 (8), pp. 778-782. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji:
Controlled Clinical Trial; Journal Article
MeSH Terms:
Benzazepines*/adverse effects
Restless Legs Syndrome*/drug therapy
Cross-Over Studies ; Dopamine Antagonists/adverse effects ; Humans
Czasopismo naukowe
Tytuł:
Dopamine D 2 and Serotonin 5-HT 1A Dimeric Receptor-Binding Monomeric Antibody scFv as a Potential Ligand for Carrying Drugs Targeting Selected Areas of the Brain.
Autorzy:
Kowalik, Agata (AUTHOR)
Majerek, Mateusz (AUTHOR)
Mrowiec, Krzysztof (AUTHOR)
Solich, Joanna (AUTHOR)
Faron-Górecka, Agata (AUTHOR)
Woźnicka, Olga (AUTHOR)
Dziedzicka-Wasylewska, Marta (AUTHOR)
Łukasiewicz, Sylwia (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Jun2022, Vol. 12 Issue 6, p749-749. 20p.
Czasopismo naukowe
Tytuł:
Enhancement of Haloperidol Binding Affinity to Dopamine Receptor via Forming a Charge-Transfer Complex with Picric Acid and 7,7,8,8-Tetracyanoquinodimethane for Improvement of the Antipsychotic Efficacy.
Autorzy:
Alamri, Abdulhakeem S. (AUTHOR)
Alhomrani, Majid (AUTHOR)
Alsanie, Walaa F. (AUTHOR)
Alyami, Hussain (AUTHOR)
Shakya, Sonam (AUTHOR)
Habeeballah, Hamza (AUTHOR)
Alamri, Abdulwahab (AUTHOR)
Alzahrani, Omar (AUTHOR)
Alzahrani, Ahmed S. (AUTHOR)
Alkhatabi, Heba A. (AUTHOR)
Felimban, Raed I. (AUTHOR)
Alhabeeb, Abdulhameed Abdullah (AUTHOR)
Raafat, Bassem M. (AUTHOR)
Refat, Moamen S. (AUTHOR)
Gaber, Ahmed (AUTHOR)
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Źródło:
Molecules. May2022, Vol. 27 Issue 10, p3295-3295. 13p.
Czasopismo naukowe
Tytuł:
Receptor-Mediated AKT/PI3K Signalling and Behavioural Alterations in Zebrafish Larvae Reveal Association between Schizophrenia and Opioid Use Disorder.
Autorzy:
Thiagarajan, Siroshini K. (AUTHOR)
Mok, Siew Ying (AUTHOR)
Ogawa, Satoshi (AUTHOR)
Parhar, Ishwar S. (AUTHOR)
Tang, Pek Yee (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. May2022, Vol. 23 Issue 9, p4715-4715. 17p.
Czasopismo naukowe

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