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Wyszukujesz frazę ""Dopaminergic"" wg kryterium: Temat


Tytuł:
LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression.
Autorzy:
Lubben N; Department of Neurodegenerative Science, Van Andel Institute, 333 Bostwick Ave NE, Grand Rapids, MI, 49503, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.
Brynildsen JK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Webb CM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Institute On Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Li HL; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Institute On Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Leyns CEG; Neuroscience Discovery, Merck & Co., Inc., Boston, MA, 02115, USA.
Changolkar L; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Institute On Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Zhang B; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Institute On Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Meymand ES; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Institute On Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, 19104, USA.
O'Reilly M; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Madaj Z; Bioinformatics and Biostatistics Core, Van Andel Institute, 333 Bostwick Ave., NE, Grand Rapids, MI, 49503, USA.
DeWeerd D; Department of Neurodegenerative Science, Van Andel Institute, 333 Bostwick Ave NE, Grand Rapids, MI, 49503, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.
Fell MJ; Neuroscience Discovery, Merck & Co., Inc., Boston, MA, 02115, USA.
Lee VMY; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Institute On Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Bassett DS; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Electrical and Systems Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Santa Fe Institute, Santa Fe, NM, 87501, USA.
Henderson MX; Department of Neurodegenerative Science, Van Andel Institute, 333 Bostwick Ave NE, Grand Rapids, MI, 49503, USA. .; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA. .
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Źródło:
Translational neurodegeneration [Transl Neurodegener] 2024 Mar 04; Vol. 13 (1), pp. 13. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Brain*
Dopaminergic Neurons*
Animals ; Humans ; Mice ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Lewy Bodies ; Mice, Transgenic ; Mutation/genetics
Czasopismo naukowe
Tytuł:
Dopamine regulates attitude toward risk.
Autorzy:
Stuphorn V; Department of Neuroscience, Johns Hopkins University School of Medicine and Zanvyl Krieger Mind/Brain Institute, Baltimore, MD, USA.; Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Jan 05; Vol. 383 (6678), pp. 32-33. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Attitude*
Dopamine*/pharmacology
Dopamine*/physiology
Dopaminergic Neurons*/physiology
Risk-Taking*
Ventral Tegmental Area*/cytology
Ventral Tegmental Area*/physiology
Animals ; Frontal Lobe/physiology ; Macaca fuscata ; Nerve Net/physiology
Czasopismo naukowe
Tytuł:
Tyrosine Metabolism Pathway Is Downregulated in Dopaminergic Neurons with LRRK2 Overexpression in Drosophila .
Autorzy:
Cheng J; Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung 40447, Taiwan.
Wu BT; Department of Senior Citizen Service Management, National Taichung University of Science and Technology, Taichung 40343, Taiwan.
Liu HP; Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Lin WY; Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung 40447, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 25; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/metabolism
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Animals ; Humans ; Drosophila/genetics ; Mutation ; Nerve Degeneration/metabolism ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł:
Current Review of the Function and Regulation of Tuberoinfundibular Dopamine Neurons.
Autorzy:
Qi-Lytle X; Department of Medical Education, Geisinger Commonwealth School of Medicine, 525 Pine St., Scranton, PA 18509, USA.
Sayers S; Department of Basic Medical Science, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second St., Pomona, CA 91766, USA.
Wagner EJ; Department of Basic Medical Science, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E. Second St., Pomona, CA 91766, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Dopamine*
Dopaminergic Neurons*
Arcuate Nucleus of Hypothalamus ; Cell Communication ; Cell Differentiation
Czasopismo naukowe
Tytuł:
Reduction in the activity of VTA/SNc dopaminergic neurons underlies aging-related decline in novelty seeking.
Autorzy:
Shan Q; Laboratory for Synaptic Plasticity, Shantou University Medical College, 515041, Shantou, Guangdong, China. .
Tian Y; Laboratory for Synaptic Plasticity, Shantou University Medical College, 515041, Shantou, Guangdong, China.
Chen H; Laboratory for Synaptic Plasticity, Shantou University Medical College, 515041, Shantou, Guangdong, China.
Lin X; Laboratory for Synaptic Plasticity, Shantou University Medical College, 515041, Shantou, Guangdong, China.
Tian Y; Chern Institute of Mathematics, Nankai University, 300071, Tianjin, China.
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Źródło:
Communications biology [Commun Biol] 2023 Dec 02; Vol. 6 (1), pp. 1224. Date of Electronic Publication: 2023 Dec 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pars Compacta*
Dopaminergic Neurons*/physiology
Humans ; Mice ; Animals ; Aged ; Exploratory Behavior ; Substantia Nigra ; Ventral Tegmental Area/physiology ; Aging
Czasopismo naukowe
Tytuł:
Neurocircuits for motivation.
Autorzy:
Stuber GD; Center for the Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA.; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA.; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Oct 27; Vol. 382 (6669), pp. 394-398. Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Dopaminergic Neurons*/physiology
Motivation*/physiology
Reward*
Ventral Tegmental Area*/physiology
Signal Transduction ; Animals
Czasopismo naukowe
Tytuł:
A Novel Rat Model of ADHD-like Hyperactivity/Impulsivity after Delayed Reward Has Selective Loss of Dopaminergic Neurons in the Right Ventral Tegmental Area.
Autorzy:
Kohe SE; Department of Anatomy, School of Biomedical Sciences, Brain Health Research Centre, University of Otago, Dunedin 9016, New Zealand.
Gowing EK; Department of Anatomy, School of Biomedical Sciences, Brain Health Research Centre, University of Otago, Dunedin 9016, New Zealand.
Seo S; Department of Anatomy, School of Biomedical Sciences, Brain Health Research Centre, University of Otago, Dunedin 9016, New Zealand.
Oorschot DE; Department of Anatomy, School of Biomedical Sciences, Brain Health Research Centre, University of Otago, Dunedin 9016, New Zealand.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 08; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/physiology
Attention Deficit Disorder with Hyperactivity*
Rats ; Animals ; Male ; Rats, Sprague-Dawley ; Ventral Tegmental Area ; Reward ; Impulsive Behavior ; Hypoxia
Czasopismo naukowe
Tytuł:
Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons.
Autorzy:
Otero MG; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Bell S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Laperle AH; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Lawless G; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Myers Z; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Castro MA; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Villalba JM; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Svendsen CN; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 18; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 18.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*
Induced Pluripotent Stem Cells*
Humans ; Cell Differentiation ; Cells, Cultured ; Organ Culture Techniques
Czasopismo naukowe
Tytuł:
The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson's Disease-Associated Neurodegeneration.
Autorzy:
Wang X; Institute of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 611731, China.; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu 611731, China.
Chen X; Institute of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 611731, China.; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu 611731, China.
Liu G; Institute of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 611731, China.; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu 611731, China.
Cai H; Transgenic Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.
Le W; Institute of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 611731, China.; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu 611731, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 11; Vol. 24 (10). Date of Electronic Publication: 2023 May 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Dopaminergic Neurons*/metabolism
Homeodomain Proteins*/genetics
Homeodomain Proteins*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/pathology
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Mice ; Dopamine ; Mesencephalon/metabolism
Czasopismo naukowe
Tytuł:
Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons.
Autorzy:
Boyd RJ; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
McClymont SA; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Barrientos NB; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Hook PW; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Law WD; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Rose RJ; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Waite EL; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Rathinavelu J; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Avramopoulos D; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
McCallion AS; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. .; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. .
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Źródło:
BMC genomics [BMC Genomics] 2023 Jun 07; Vol. 24 (1), pp. 306. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Mice ; Humans ; Animals ; Mesencephalon/metabolism ; Cell Line ; Cell Differentiation ; Chromatin/metabolism
Czasopismo naukowe
Tytuł:
Subthalamic neurons interact with nigral dopaminergic neurons to regulate movement in mice.
Autorzy:
Fan JP; School of basic medical sciences, Xuzhou Medical University, Xuzhou, China.; Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Zhang X; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.
Han Y; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.
Ji Y; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.
Gu WX; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Department of Anesthesiology, Drum Tower Hospital, affiliated to Nanjing University, Nanjing, China.
Wu HC; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Department of Anesthesiology, Drum Tower Hospital, affiliated to Nanjing University, Nanjing, China.
Zhou C; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory in Anesthesiology, Xuzhou Medical University, Xuzhou, China.
Xiao C; School of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory in Anesthesiology, Xuzhou Medical University, Xuzhou, China.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2023 Mar; Vol. 237 (3), pp. e13917. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopaminergic Neurons*/physiology
Substantia Nigra*
Mice ; Animals ; Oxidopamine ; Electrophysiological Phenomena ; Locomotion
Czasopismo naukowe
Tytuł:
Integrative Roles of Dopamine Pathway and Calcium Channels Reveal a Link between Schizophrenia and Opioid Use Disorder.
Autorzy:
Thiagarajan SK; Department of Mechatronics and Biomedical Engineering, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
Mok SY; Department of Mechatronics and Biomedical Engineering, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
Ogawa S; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Malaysia.
Parhar IS; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya 47500, Malaysia.
Tang PY; Department of Mechatronics and Biomedical Engineering, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 17; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Channels*/metabolism
Dopamine*/metabolism
Dopaminergic Neurons*/drug effects
Dopaminergic Neurons*/metabolism
Morphine*/administration & dosage
Morphine*/pharmacology
Opioid-Related Disorders*/metabolism
Schizophrenia*/metabolism
Domperidone*/administration & dosage
Domperidone*/pharmacology
Dopamine Antagonists*/administration & dosage
Dopamine Antagonists*/pharmacology
Animals ; Zebrafish ; Locomotion/drug effects ; Metabolic Networks and Pathways
Czasopismo naukowe
Tytuł:
Prolonged Differentiation of Neuron-Astrocyte Co-Cultures Results in Emergence of Dopaminergic Neurons.
Autorzy:
de Leeuw VC; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.
van Oostrom CTM; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.
Zwart EP; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.
Heusinkveld HJ; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.
Hessel EVS; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 10; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/metabolism
Neural Stem Cells*/metabolism
Humans ; Dopamine/metabolism ; Coculture Techniques ; Astrocytes/metabolism ; Cell Differentiation/physiology
Czasopismo naukowe
Tytuł:
Upregulation of DJ-1 in Dopaminergic Neurons by a Physically-Modified Saline: Implications for Parkinson's Disease.
Autorzy:
Jana M; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Dasarathy S; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Ghosh S; Revalesio Corporation, Tacoma, WA 98421, USA.
Pahan K; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 28; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/metabolism
Parkinson Disease*/metabolism
Protein Deglycase DJ-1*/metabolism
Animals ; Humans ; Mice ; Oxidative Stress ; Saline Solution ; Up-Regulation
Czasopismo naukowe
Tytuł:
Preservation of dendritic D2 receptor transmission in substantia nigra dopamine neurons with age.
Autorzy:
Troyano-Rodriguez E; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Blankenship HE; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Handa K; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Branch SY; Department of Cellular and Integrative Physiology, University of Texas Health, San Antonio, TX, USA.
Beckstead MJ; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA. .; Oklahoma City VA Medical Center, Oklahoma City, OK, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 19; Vol. 13 (1), pp. 1025. Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopaminergic Neurons*/metabolism
Dopamine*
Mice ; Male ; Animals ; Kinetics ; Substantia Nigra/metabolism ; Pars Compacta/metabolism ; Receptors, Dopamine D2/metabolism
Czasopismo naukowe
Tytuł:
Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates.
Autorzy:
Faustini G; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Longhena F; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Muscò A; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Bono F; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Parrella E; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
La Via L; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Barbon A; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Pizzi M; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Onofri F; Department of Experimental Medicine, University of Genova, Via Leon Battista Alberti 2, 16132 Genova, Italy.
Benfenati F; IRCSS Policlinico San Martino Hospital, Largo Rosanna Benzi 10, 16132 Genova, Italy.; Italian Institute of Technology, Via Morego 30, 16163 Genova, Italy.
Missale C; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Memo M; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Zizioli D; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Bellucci A; Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.; Laboratory for Preventive and Personalized Medicine, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
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Źródło:
Cells [Cells] 2022 Dec 02; Vol. 11 (23). Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/metabolism
Synapsins*/genetics
Synapsins*/metabolism
Animals ; Humans ; Mice ; Brain-Derived Neurotrophic Factor/genetics ; Dopamine ; Induced Pluripotent Stem Cells/metabolism ; Methylphenidate/therapeutic use ; Mice, Knockout ; Zebrafish/metabolism
Czasopismo naukowe
Tytuł:
Bilirubin Prevents the TH Dopaminergic Neuron Loss in a Parkinson's Disease Model by Acting on TNF-α.
Autorzy:
Jayanti S; The Liver-Brain Unit 'Rita-Moretti', Fondazione Italiana Fegato-Onlus, Bldg. Q, AREA Science Park, ss14, Km 163.5, Basovizza, 34149 Trieste, Italy.; Faculty of Medicine, University of Hasanuddin, Makassar 90245, Indonesia.; Molecular Biomedicine Ph.D. Program, Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Moretti R; Neurology Clinic, Department of Medical, Surgical and Health Sciences, University of Trieste, 34139 Trieste, Italy.
Tiribelli C; The Liver-Brain Unit 'Rita-Moretti', Fondazione Italiana Fegato-Onlus, Bldg. Q, AREA Science Park, ss14, Km 163.5, Basovizza, 34149 Trieste, Italy.
Gazzin S; The Liver-Brain Unit 'Rita-Moretti', Fondazione Italiana Fegato-Onlus, Bldg. Q, AREA Science Park, ss14, Km 163.5, Basovizza, 34149 Trieste, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 17; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*
Parkinson Disease*/drug therapy
Parkinson Disease*/pathology
Humans ; Tumor Necrosis Factor-alpha/pharmacology ; Bilirubin/pharmacology ; Bilirubin/therapeutic use ; Nerve Degeneration/pathology ; Dopamine/pharmacology ; Rotenone/pharmacology
Czasopismo naukowe
Tytuł:
A LRRK2/dLRRK-mediated lysosomal pathway that contributes to glial cell death and DA neuron survival.
Autorzy:
Wang L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Wang H; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Yi S; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zhang S; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Ho MS; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2022 Oct; Vol. 23 (10), pp. 506-520. Date of Electronic Publication: 2022 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cathepsin B*/genetics
Cathepsin B*/metabolism
Dopaminergic Neurons*/metabolism
Cell Death ; Leucine/genetics ; Leucine/metabolism ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism ; Lysosomes/metabolism ; Mutation ; Neuroglia/metabolism
Czasopismo naukowe
Tytuł:
Automated quantification of dopaminergic immunostained neurons in substantia nigra using freely available software.
Autorzy:
Bonaccorso Marinelli MP; Instituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza, Huarpes 630, 5500, Mendoza, Argentina.; Instituto de Medicina y Biología Experimental de Cuyo (IMBECU)-CONICET, Universidad Nacional de Cuyo, at Av. Dr. Adrián Ruiz Leal, 5500, Mendoza, Argentina.; Instituto de Bioingeniería-Facultad de Ingeniería-Universidad de Mendoza, Av. Boulogne Sur Mer 683, 5500, Mendoza, Argentina.
Baiardi G; Laboratorio de Neurofarmacología, (IIBYT-CONICET), Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Universidad Católica de Córdoba, Córdoba, Argentina.
Valdez SR; Laboratorio de Reproducción y Lactancia, Instituto de Medicina y Biología Experimental de Cuyo (IMBECU)-CONICET, Universidad Nacional de Cuyo, Av. Dr. Adrián Ruiz Leal, 5500, Mendoza, Argentina.; Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, at Padre J. Contreras 1300, 5500, Mendoza, Argentina.
Cabrera RJ; Instituto de Investigaciones Biomédicas (INBIOMED), Universidad de Mendoza, Huarpes 630, 5500, Mendoza, Argentina. .; Instituto de Medicina y Biología Experimental de Cuyo (IMBECU)-CONICET, Universidad Nacional de Cuyo, at Av. Dr. Adrián Ruiz Leal, 5500, Mendoza, Argentina. .
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Źródło:
Medical & biological engineering & computing [Med Biol Eng Comput] 2022 Oct; Vol. 60 (10), pp. 2995-3007. Date of Electronic Publication: 2022 Aug 26.
Typ publikacji:
Journal Article
MeSH Terms:
Dopaminergic Neurons*/metabolism
Tyrosine 3-Monooxygenase*/metabolism
Animals ; Male ; Oxidopamine/toxicity ; Rats ; Software ; Substantia Nigra/metabolism ; Substantia Nigra/pathology
Czasopismo naukowe
Tytuł:
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Autorzy:
Yang QY; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Li XW; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Yang R; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Qin TY; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Long H; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Zhang SB; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
Zhang F; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Center, Zunyi Medical University, Zunyi, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2022 Oct; Vol. 28 (10), pp. 1624-1636. Date of Electronic Publication: 2022 Jul 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopaminergic Neurons*
Lipopolysaccharides*/toxicity
Animals ; Biomarkers/metabolism ; Inflammation/metabolism ; Injections, Intraperitoneal ; Mesencephalon/metabolism ; Microglia ; RNA, Messenger/metabolism ; Rats ; Substantia Nigra
Czasopismo naukowe

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