Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors.
Autorzy :
Namer B; Institute of Physiology and Pathophysiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; Department of Experimental Pain Research, Medical Faculty Mannheim of Heidelberg University, Germany; Interdisciplinary Center for Clinical Research within the faculty of Medicine at the RWTH Aachen University, 52074 Aachen, Germany. Schmidt D; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. Eberhardt E; Department of Anesthesiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. Maroni M; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; Department of Anesthesiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. DorfmeisterE; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. Kleggetveit IP; Department of Neurology, Oslo University Hospital-Rikshospitalet, Oslo, Norway. Kaluza L; Institute of Physiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Meents J; Institute of Physiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Gerlach A; Icagen, Durham, NC 27703, USA. Lin Z; Icagen, Durham, NC 27703, USA. Winterpacht A; Institute of Human Genetics, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Dragicevic E; Nanion Technologies GmbH, 80636 Munich, Germany. Kohl Z; Department of Molecular Neurology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. Schüttler J; Department of Anesthesiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. Kurth I; Institute of Human Genetics, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Warncke T; Department of Anesthesiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany. Jorum E; Department of Neurology, Oslo University Hospital-Rikshospitalet, Oslo, Norway; Section of Clinical Neurophysiology, Department of Neurology, Oslo University Hospital-Rikshospitalet, Oslo, Norway. Winner B; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; Center of Rare Diseases Erlangen (ZSEER), Germany. Electronic address: . Lampert A; Institute of Physiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2019 Jan; Vol. 39, pp. 401-408. Date of Electronic Publication: 2018 Nov 28.
Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model.
Autorzy :
Sommer A; IZKF Junior Research Group 3 and BMBF Research Group Neuroscience, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Glückstrasse 6, 91054, Erlangen, Germany.; Bavarian Research Network on Induced Pluripotent Stem Cells ('ForIPS'), Erlangen, Germany. Fadler T; IZKF Junior Research Group 3 and BMBF Research Group Neuroscience, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Glückstrasse 6, 91054, Erlangen, Germany. DorfmeisterE; IZKF Junior Research Group 3 and BMBF Research Group Neuroscience, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Glückstrasse 6, 91054, Erlangen, Germany. Hoffmann AC; Institute of Biochemistry (Emil-Fischer-Center), FAU Erlangen-Nürnberg, Fahrstrasse 17, 91054, Erlangen, Germany. Xiang W; Institute of Biochemistry (Emil-Fischer-Center), FAU Erlangen-Nürnberg, Fahrstrasse 17, 91054, Erlangen, Germany. Winner B; IZKF Junior Research Group 3 and BMBF Research Group Neuroscience, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Glückstrasse 6, 91054, Erlangen, Germany.; Bavarian Research Network on Induced Pluripotent Stem Cells ('ForIPS'), Erlangen, Germany.; Institute of Human Genetics, FAU Erlangen-Nürnberg, Schwabachanlage 10, 91054, Erlangen, Germany. Prots I; IZKF Junior Research Group 3 and BMBF Research Group Neuroscience, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Glückstrasse 6, 91054, Erlangen, Germany. .; Bavarian Research Network on Induced Pluripotent Stem Cells ('ForIPS'), Erlangen, Germany. .
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Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2016 Jun 30; Vol. 13 (1), pp. 174. Date of Electronic Publication: 2016 Jun 30.
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