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Tytuł:
Clinical update on the use of biomarkers of airway inflammation in the management of asthma
Autorzy:
Dorscheid DR
Sin DD
Wadsworth SJ
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Temat:
Immunologic diseases. Allergy
RC581-607
Źródło:
Journal of Asthma and Allergy, Vol 2011, Iss default, Pp 77-86 (2011)
Opis pliku:
electronic resource
Relacje:
http://www.dovepress.com/clinical-update-on-the-use-of-biomarkers-of-airway-inflammation-in-the-a7771; https://doaj.org/toc/1178-6965
Dostęp URL:
https://doaj.org/article/a97d689471874134bf494d6708ef42cf  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Lipid nanoparticle formulations for optimal RNA-based topical delivery to murine airways.
Autorzy:
Tam, A (AUTHOR)
Kulkarni, J (AUTHOR)
An, K (AUTHOR)
Li, L (AUTHOR)
Dorscheid, DR (AUTHOR)
Singhera, GK (AUTHOR)
Bernatchez, P (AUTHOR)
Reid, GSD (AUTHOR)
Chan, KYT (AUTHOR)
Witzigmann, D (AUTHOR)
Cullis, PR (AUTHOR)
Sin, DD (AUTHOR)
Lim, CJ (AUTHOR)
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Źródło:
European Journal of Pharmaceutical Sciences. Sep2022, Vol. 176, pN.PAG-N.PAG. 1p.
Czasopismo naukowe
Szczegóły
Tytuł:
Airway Epithelial-Derived Immune Mediators in COVID-19.
Autorzy:
Guo TJF; Centre for Heart Lung Innovation, Providence Healthcare Research Institute, St. Paul's Hospital, University of British Columbia, 1081 Burrard St., Vancouver, BC V6Z 1Y6, Canada.
Singhera GK; Centre for Heart Lung Innovation, Providence Healthcare Research Institute, St. Paul's Hospital, University of British Columbia, 1081 Burrard St., Vancouver, BC V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, 2775 Laurel St., Vancouver, BC V5Z 1M9, Canada.
Leung JM; Centre for Heart Lung Innovation, Providence Healthcare Research Institute, St. Paul's Hospital, University of British Columbia, 1081 Burrard St., Vancouver, BC V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, 2775 Laurel St., Vancouver, BC V5Z 1M9, Canada.
Dorscheid DR; Centre for Heart Lung Innovation, Providence Healthcare Research Institute, St. Paul's Hospital, University of British Columbia, 1081 Burrard St., Vancouver, BC V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, 2775 Laurel St., Vancouver, BC V5Z 1M9, Canada.
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Źródło:
Viruses [Viruses] 2023 Jul 29; Vol. 15 (8). Date of Electronic Publication: 2023 Jul 29.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Pneumonia, Viral*
Humans ; SARS-CoV-2 ; Immunologic Factors ; Cytokines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma.
Autorzy:
Tam A; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC V6H 0B3, Canada.
Osei ET; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.; Department of Biology, Okanagan Campus, University of British Columbia, Kelowna, BC V1V 1V7, Canada.
Cheung CY; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
Hughes M; School of Biomedical Engineering, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Yang CX; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
McNagny KM; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.; School of Biomedical Engineering, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Dorscheid DR; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
Singhera GK; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
Hallstrand TS; Division of Pulmonary, Critical Care, Sleep Medicine and the Center for Lung Biology, University of Washington, Seattle, WA 98195-6522, USA.
Warner S; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
Hogg JC; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
Hackett TL; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
Lim CJ; Department of Pediatrics, University of British Columbia, Vancouver, BC V6H 0B3, Canada.
Sin DD; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada.
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Źródło:
Cells [Cells] 2022 Sep 27; Vol. 11 (19). Date of Electronic Publication: 2022 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Airway Remodeling*
Asthma*
Animals ; Dermatophagoides pteronyssinus ; Genome-Wide Association Study ; Hedgehog Proteins/metabolism ; Humans ; Inflammation ; Ligands ; Matrix Metalloproteinase 2/genetics ; Mice ; Mice, Inbred C57BL ; Patched-1 Receptor/genetics ; Patched-1 Receptor/metabolism ; Phosphates ; Pyroglyphidae ; RNA, Small Interfering ; Transforming Growth Factor beta1/metabolism ; Zinc Finger Protein GLI1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-4Rα blockade reduces influenza-associated morbidity in a murine model of allergic asthma.
Autorzy:
Shahangian K; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Ngan DA; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Chen HHR; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Oh Y; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Tam A; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Wen J; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Cheung C; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Knight DA; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.
Dorscheid DR; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Hackett TL; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Hughes MR; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.; The Biomedical Research Centre, University of British Columbia, Vancouver, BC, Canada.
McNagny KM; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.; The Biomedical Research Centre, University of British Columbia, Vancouver, BC, Canada.
Hirota JA; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Niikura M; Department of Health Sciences, Simon Fraser University, Vancouver, BC, Canada.
Man SFP; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Sin DD; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Room 166, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada. .; Department of Medicine, University of British Columbia, Vancouver, BC, Canada. .
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Źródło:
Respiratory research [Respir Res] 2021 Mar 02; Vol. 22 (1), pp. 75. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma/*metabolism
Hypersensitivity/*metabolism
Influenza, Human/*metabolism
Pyroglyphidae/*metabolism
Receptors, Cell Surface/*antagonists & inhibitors
Receptors, Cell Surface/*metabolism
Animals ; Antibodies, Monoclonal/administration & dosage ; Asthma/chemically induced ; Asthma/drug therapy ; Disease Models, Animal ; Humans ; Hypersensitivity/drug therapy ; Influenza A Virus, H1N1 Subtype/drug effects ; Influenza A Virus, H1N1 Subtype/physiology ; Influenza, Human/drug therapy ; Male ; Mice ; Mice, Inbred BALB C
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Olodaterol exerts anti-inflammatory effects on COPD airway epithelial cells.
Autorzy:
Yang N; Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Singhera GK; Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Yan YX; Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Pieper MP; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany.
Leung JM; Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Sin DD; Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Dorscheid DR; Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. del.dorscheid@hli.ubc.ca.
Pokaż więcej
Źródło:
Respiratory research [Respir Res] 2021 Feb 23; Vol. 22 (1), pp. 65. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Benzoxazines/*administration & dosage
Inflammation/*drug therapy
Pulmonary Disease, Chronic Obstructive/*drug therapy
Respiratory Mucosa/*drug effects
Administration, Inhalation ; Aged ; Bronchodilator Agents/administration & dosage ; Cells, Cultured ; Epithelial Cells ; Female ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/metabolism ; Pulmonary Disease, Chronic Obstructive/pathology ; Respiratory Mucosa/metabolism ; Respiratory Mucosa/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Omalizumab in patients with severe asthma and persistent sputum eosinophilia.
Autorzy:
Mukherjee M; 1Department of Medicine, Division of Respirology, McMaster University, Hamilton, ON Canada.; Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6 Canada.
Kjarsgaard M; 1Department of Medicine, Division of Respirology, McMaster University, Hamilton, ON Canada.; Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6 Canada.
Radford K; 1Department of Medicine, Division of Respirology, McMaster University, Hamilton, ON Canada.; Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6 Canada.
Huang C; 1Department of Medicine, Division of Respirology, McMaster University, Hamilton, ON Canada.; Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6 Canada.
Leigh R; 3Department of Medicine, University of Calgary, Calgary, Canada.
Dorscheid DR; 4Department of Medicine, University of British Columbia, Vancouver, BC Canada.
Lemiere C; 5Faculty of Medicine, Université de Montréal, Montreal, QC Canada.
Boulet LP; 6Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ), Université Laval, Quebec, QC Canada.
Waserman S; 1Department of Medicine, Division of Respirology, McMaster University, Hamilton, ON Canada.; Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6 Canada.
Martin J; 7Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine, McGill University, Montreal, QC Canada.; 8Meakins-Christie Laboratories, Research Institute of the McGill University Health Centre, Montreal, Canada.
Nair P; 1Department of Medicine, Division of Respirology, McMaster University, Hamilton, ON Canada.; Firestone Institute for Respiratory Health, St Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6 Canada.
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Źródło:
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology [Allergy Asthma Clin Immunol] 2019 Apr 03; Vol. 15, pp. 21. Date of Electronic Publication: 2019 Apr 03 (Print Publication: 2019).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease.
Autorzy:
Tam A; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Hughes M; Biomedical Research Centre (BRC), University of British Columbia, Vancouver, British Columbia, Canada.
McNagny KM; Biomedical Research Centre (BRC), University of British Columbia, Vancouver, British Columbia, Canada.
Obeidat M; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Hackett TL; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.; Department of Anaesthesiology, Pharmacology, & Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada.
Leung JM; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Shaipanich T; Division of Respiratory Medicine, Department of Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Dorscheid DR; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Singhera GK; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Yang CWT; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Paré PD; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Hogg JC; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Nickle D; Merck & Co. Inc., Rahway, New Jersey, United States of America.
Sin DD; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2019 Mar 04; Vol. 9 (1), pp. 3353. Date of Electronic Publication: 2019 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*
Bronchi/*metabolism
Patched-1 Receptor/*metabolism
Pulmonary Disease, Chronic Obstructive/*metabolism
Adult ; Aged ; Animals ; Epithelium/metabolism ; Female ; Gene Silencing ; Humans ; Male ; Mice ; Mice, Knockout ; Middle Aged ; Patched-1 Receptor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptomic and proteomic host response to Aspergillus fumigatus conidia in an air-liquid interface model of human bronchial epithelium.
Autorzy:
Toor A; Experimental Medicine, University of British Columbia, Vancouver, Canada.; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, Canada.
Culibrk L; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, Canada.
Singhera GK; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, Canada.
Moon KM; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada.
Prudova A; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada.
Foster LJ; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada.
Moore MM; Department of Biological Sciences, Simon Fraser University, Burnaby, Canada.
Dorscheid DR; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, Canada.; Department of Medicine, Division of Respiratory Medicine, University of British Columbia, Vancouver, Canada.
Tebbutt SJ; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, Canada.; Department of Medicine, Division of Respiratory Medicine, University of British Columbia, Vancouver, Canada.; Prevention of Organ Failure (PROOF) Centre of Excellence, Vancouver, Canada.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2018 Dec 27; Vol. 13 (12), pp. e0209652. Date of Electronic Publication: 2018 Dec 27 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
Host-Pathogen Interactions*
Proteomics*
Aspergillosis/*genetics
Aspergillosis/*metabolism
Aspergillus fumigatus/*physiology
Respiratory Mucosa/*metabolism
Respiratory Mucosa/*microbiology
Aspergillosis/microbiology ; Aspergillosis/pathology ; Computational Biology/methods ; Gene Ontology ; Humans ; Proteome ; Respiratory Mucosa/pathology ; Spores, Fungal ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro.
Autorzy:
Hirota JA; 1James Hogg Research Centre, University of British Columbia , Vancouver, British Columbia , Canada.
Marchant DJ
Singhera GK
Moheimani F
Dorscheid DR
Carlsten C
Sin D
Knight D
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Źródło:
Experimental lung research [Exp Lung Res] 2015; Vol. 41 (6), pp. 353-62. Date of Electronic Publication: 2015 Jul 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial Cells/*immunology
Influenza A Virus, H1N1 Subtype/*immunology
Influenza, Human/*immunology
Interleukin-1beta/*immunology
Particulate Matter/*immunology
Respiratory System/*immunology
Respiratory System/*virology
Air Pollution/adverse effects ; Allergens/immunology ; Cell Line ; Epithelial Cells/virology ; Humans ; Inflammasomes/immunology ; Influenza, Human/virology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness.
Autorzy:
Chitano P; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina James Hogg Research Centre, Institute for Heart and Lung Innovation and Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Wang L; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina James Hogg Research Centre, Institute for Heart and Lung Innovation and Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Degan S; Duke Center for Molecular and Biomolecular Imaging, Duke University Medical Center, Durham, North Carolina Duke Department of Radiology, Duke University Medical Center, Durham, North Carolina.
Worthington CL; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Pozzato V; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Hussaini SH; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Turner WC; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Dorscheid DR; James Hogg Research Centre, Institute for Heart and Lung Innovation and Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Murphy TM; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
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Źródło:
Physiological reports [Physiol Rep] 2014 Dec 11; Vol. 2 (12). Date of Electronic Publication: 2014 Dec 11 (Print Publication: 2014).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Conjugated linoleic acid improves airway hyper-reactivity in overweight mild asthmatics.
Autorzy:
MacRedmond R; Providence Healthcare Heart+Lung Institute, St Paul's Hospital, University of British Columbia, Vancouver, Canada. />Singhera G
Attridge S
Bahzad M
Fava C
Lai Y
Hallstrand TS
Dorscheid DR
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2010 Jul; Vol. 40 (7), pp. 1071-8.
Typ publikacji:
Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Asthmatic Agents/*therapeutic use
Asthma/*complications
Asthma/*drug therapy
Linoleic Acids, Conjugated/*therapeutic use
Overweight/*complications
Adult ; Asthma/immunology ; Dietary Supplements ; Double-Blind Method ; Female ; Humans ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sialyl Lewis X modification of the epidermal growth factor receptor regulates receptor function during airway epithelial wound repair.
Autorzy:
Allahverdian S; Department of Medicine, UBC James Hogg Research Centre, Providence Heart+Lung Institute, St. Paul's Hospital, University of British Columbia, Vancouver, Canada.
Wang A
Singhera GK
Wong BW
Dorscheid DR
Pokaż więcej
Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2010 Apr; Vol. 40 (4), pp. 607-18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bronchi*/injuries
Bronchi*/metabolism
Gene Expression Regulation*
Epithelial Cells/*metabolism
ErbB Receptors/*metabolism
Oligosaccharides/*metabolism
Wound Healing/*physiology
Cells, Cultured ; ErbB Receptors/genetics ; Fucosyltransferases/genetics ; Fucosyltransferases/metabolism ; Glycosylation ; Humans ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Sialyl Lewis X Antigen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Interleukin-9 and -13 inhibit spontaneous and corticosteroid induced apoptosis of normal airway epithelial cells.
Autorzy:
Singhera GK; Providence Healthcare Heart, Lung Institute, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
MacRedmond R
Dorscheid DR
Pokaż więcej
Źródło:
Experimental lung research [Exp Lung Res] 2008 Nov; Vol. 34 (9), pp. 579-98.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adrenal Cortex Hormones/*pharmacology
Apoptosis/*drug effects
Epithelial Cells/*cytology
Interleukin-13/*pharmacology
Interleukin-9/*pharmacology
Respiratory System/*cytology
Cell Proliferation ; Cells, Cultured ; Hemostasis ; Humans ; Protective Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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