Autor: "Dotta, F." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Identification and Validation of miR-222-3p and miR-409-3p as Plasma Biomarkers in Gestational Diabetes Mellitus Sharing Validated Target Genes Involved in Metabolic Homeostasis.
Autorzy:: Filardi T; Department of Experimental Medicine, 'Sapienza' University, 00161 Rome, Italy.
Catanzaro G; Department of Experimental Medicine, 'Sapienza' University, 00161 Rome, Italy.
Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto di Mario, Toscana Life Sciences, 53100 Siena, Italy.
Splendiani E; Department of Molecular Medicine, 'Sapienza' University, 00161 Rome, Italy.
Trocchianesi S; Department of Molecular Medicine, 'Sapienza' University, 00161 Rome, Italy.
Santangelo C; Center for Gender-Specific Medicine, Gender Specific Prevention and Health Unit, Istituto Superiore di Sanità, 00161 Rome, Italy.
Brunelli R; Maternal and Child Health and Urological Sciences, 'Sapienza' University, 00161 Rome, Italy.
Guarino E; UOC Diabetologia, Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy.
Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto di Mario, Toscana Life Sciences, 53100 Siena, Italy.
Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto di Mario, Toscana Life Sciences, 53100 Siena, Italy.; UOC Diabetologia, Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy.; Tuscany Centre for Precision Medicine (CReMeP), 53100 Siena, Italy.
Morano S; Department of Experimental Medicine, 'Sapienza' University, 00161 Rome, Italy.
Ferretti E; Department of Experimental Medicine, 'Sapienza' University, 00161 Rome, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 12; Vol. 23 (8). Date of Electronic Publication: 2022 Apr 12.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*
Diabetes, Gestational*/genetics
MicroRNAs*/metabolism
Biomarkers ; Female ; Homeostasis/genetics ; Humans ; Pregnancy

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Skocz do pozycji: 2.

Tytuł:: Circulating microRNAs Signature for Predicting Response to GLP1-RA Therapy in Type 2 Diabetic Patients: A Pilot Study.
Autorzy:: Formichi C; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Fignani D; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Nigi L; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Brusco N; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Licata G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Sabato C; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Ferretti E; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.; Tuscany Centre for Precision Medicine (CReMeP), 53100 Siena, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 31; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:: Journal Article
MeSH Terms:: Circulating MicroRNA/*analysis
Circulating MicroRNA/*genetics
Diabetes Mellitus, Type 2/*genetics
Adult ; Biomarkers, Pharmacological/blood ; Blood Glucose/analysis ; Diabetes Mellitus, Type 2/metabolism ; Female ; Gene Expression/genetics ; Gene Expression Profiling/methods ; Glucagon-Like Peptide 1/metabolism ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/metabolism ; Glucose/metabolism ; Humans ; Hypoglycemic Agents/pharmacology ; Male ; MicroRNAs/blood ; MicroRNAs/genetics ; Middle Aged ; Pilot Projects ; Transcriptome/genetics

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Skocz do pozycji: 3.

Tytuł:: The Landscape of microRNAs in βCell: Between Phenotype Maintenance and Protection.
Autorzy:: Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Brusco N; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Licata G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Fignani D; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Formichi C; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Nigi L; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.
Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.; Fondazione Umberto Di Mario, c/o Toscana Life Sciences, 53100 Siena, Italy.; Tuscany Centre for Precision Medicine (CReMeP), 53100 Siena, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 14; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 14.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Gene Expression Regulation*
Diabetes Mellitus, Type 1/*genetics
Diabetes Mellitus, Type 2/*genetics
Insulin-Secreting Cells/*metabolism
MicroRNAs/*genetics
Animals ; Humans ; Hyperglycemia/genetics ; Hyperglycemia/metabolism ; Insulin Secretion/genetics ; Insulin-Secreting Cells/cytology ; Phenotype

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Skocz do pozycji: 4.

Tytuł:: MicroRNA Expression in the Aqueous Humor of Patients with Diabetic Macular Edema.
Autorzy:: Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Viale Bracci, 16, 53100 Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Sciences, 53100 Siena, Italy.
Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Viale Bracci, 16, 53100 Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Sciences, 53100 Siena, Italy.
Eandi CM; Department of Surgical Science, University of Torino, 10124 Torino, Italy.; Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, 1004 Lausanne, Switzerland.
Neri G; Ophthalmology Unit of the Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Nigi L; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Viale Bracci, 16, 53100 Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Sciences, 53100 Siena, Italy.
Brusco N; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Viale Bracci, 16, 53100 Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Sciences, 53100 Siena, Italy.
D'Aurizio R; Institute of Informatics and Telematics, National Research Council, 56124 Pisa, Italy.
Posarelli M; Ophthalmology Unit of the Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Bacci T; Ophthalmology Unit of the Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Benedetto E; Ophthalmology Unit of the Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Fruschelli M; Ophthalmology Unit of the Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Orlandini M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Galvagni F; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Viale Bracci, 16, 53100 Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Sciences, 53100 Siena, Italy.
Tosi GM; Ophthalmology Unit of the Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 03; Vol. 21 (19). Date of Electronic Publication: 2020 Oct 03.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2/*genetics
Diabetic Retinopathy/*genetics
Macular Edema/*genetics
MicroRNAs/*genetics
Aged ; Aged, 80 and over ; Aqueous Humor/metabolism ; Diabetes Mellitus, Type 2/pathology ; Diabetic Retinopathy/pathology ; Female ; Gene Expression Regulation/genetics ; Humans ; Macular Edema/pathology ; Male ; Middle Aged

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Skocz do pozycji: 5.

Tytuł:: MicroRNAs as Regulators of Insulin Signaling: Research Updates and Potential Therapeutic Perspectives in Type 2 Diabetes.
Autorzy:: Nigi L; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .
Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .
Ventriglia G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .
Brusco N; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .
Mancarella F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .
Formichi C; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .
Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. francesco.dotta@alice.it.
Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, 53100 Siena, Italy. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Nov 22; Vol. 19 (12). Date of Electronic Publication: 2018 Nov 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Signal Transduction*
Diabetes Mellitus, Type 2/*metabolism
Insulin/*metabolism
MicroRNAs/*genetics
Animals ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/therapy ; Humans ; MicroRNAs/metabolism ; RNAi Therapeutics

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Skocz do pozycji: 6.

Tytuł:: Long-term changes in cardiovascular risk markers during administration of exenatide twice daily or glimepiride: results from the European exenatide study.
Autorzy:: Simó R; CIREDEM, Carlos III Health Institute, Barcelona, Spain. .; Diabetes Research and Metabolism Unit, Institut de Recerca Hospital Universitari Vall d'Hebron, Barcelona, Spain. .
Guerci B; Diabetologie, Maladies Metaboliques and Nutrition, Hôpital Brabois, CHU de Nancy, et CIC Inserm, Vandoeuvre Lès Nancy, France. .
Schernthaner G; Rudolfstiftung Hospital-Vienna, Vienna, Austria. .
Gallwitz B; Medizinische Klinik IV, Universitätsklinikum Tübingen, Tübingen, Germany. .
Rosas-Guzmàn J; Celaya Center for Specialist Medicine, Celaya, Guanajuato, Mexico. .
Dotta F; Diabetes Unit, Policlinico Le Scotte, University of Siena, Siena, Italy. francesco.dotta@alice.it.
Festa A; Eli Lilly and Company, Eli Lilly Regional Operations Ges.m.b.H., Vienna, Austria. festa_.
Zhou M; Bristol-Myers Squibb, Pennington, NJ, USA. .
Kiljański J; Eli Lilly, Eli Lilly and Company, Eli Lilly Polska Sp. z o.o., Warsaw, Poland. kiljanski_.; Pokaż więcej
Źródło:: Cardiovascular diabetology [Cardiovasc Diabetol] 2015 Sep 04; Vol. 14, pp. 116. Date of Electronic Publication: 2015 Sep 04.
Typ publikacji:: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Cardiovascular Diseases/*prevention & control
Diabetes Mellitus, Type 2/*drug therapy
Hypoglycemic Agents/*administration & dosage
Incretins/*administration & dosage
Peptides/*administration & dosage
Sulfonylurea Compounds/*administration & dosage
Venoms/*administration & dosage
Aged ; Biomarkers/blood ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Blood Pressure/drug effects ; C-Reactive Protein/metabolism ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/physiopathology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/physiopathology ; Drug Administration Schedule ; Drug Therapy, Combination ; Europe ; Exenatide ; Female ; Glycated Hemoglobin/metabolism ; Heart Rate/drug effects ; Humans ; Hypoglycemic Agents/adverse effects ; Incretins/adverse effects ; Lipids/blood ; Male ; Metformin/administration & dosage ; Middle Aged ; Peptides/adverse effects ; Risk Factors ; Sulfonylurea Compounds/adverse effects ; Time Factors ; Treatment Outcome ; Venoms/adverse effects

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