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Tytuł :
Highly atypical double barrel outlet to aorta in double inlet left ventricle, double outlet right ventricle.
Autorzy :
Priya S; Department of Radiology, University of Iowa Hospitals & Clinics, IA, 52242, USA.
Ashwath R; Department of Pediatric Cardiology, University of Iowa Hospitals & Clinics, IA, 52242, USA. Electronic address: .
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Źródło :
Journal of cardiovascular computed tomography [J Cardiovasc Comput Tomogr] 2020 Sep - Oct; Vol. 14 (5), pp. e63-e65. Date of Electronic Publication: 2019 Mar 14.
Typ publikacji :
Case Reports; Video-Audio Media
MeSH Terms :
Computed Tomography Angiography*
Coronary Angiography*
Abnormalities, Multiple/*diagnostic imaging
Aorta/*diagnostic imaging
Double Outlet Right Ventricle/*diagnostic imaging
Vascular Malformations/*diagnostic imaging
Abnormalities, Multiple/physiopathology ; Abnormalities, Multiple/surgery ; Aorta/abnormalities ; Aorta/physiopathology ; Aorta/surgery ; Cardiac-Gated Imaging Techniques ; Double Outlet Right Ventricle/physiopathology ; Double Outlet Right Ventricle/surgery ; Electrocardiography ; Female ; Humans ; Infant, Newborn ; Predictive Value of Tests ; Treatment Outcome ; Vascular Malformations/physiopathology ; Vascular Malformations/surgery
Raport
Tytuł :
Diagnostic performance of fetal intelligent navigation echocardiography (FINE) in fetuses with double-outlet right ventricle (DORV).
Autorzy :
Ma M; Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, People's Republic of China.
Li Y; Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, People's Republic of China.
Chen R; Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, People's Republic of China.
Huang C; Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, People's Republic of China.
Mao Y; Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, People's Republic of China.
Zhao B; Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine, Hangzhou, People's Republic of China. .
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Źródło :
The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2020 Nov; Vol. 36 (11), pp. 2165-2172. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Artificial Intelligence*
Diagnosis, Computer-Assisted*
Echocardiography, Four-Dimensional*
Ultrasonography, Prenatal*
Double Outlet Right Ventricle/*diagnostic imaging
Fetal Heart/*diagnostic imaging
Adult ; Anatomic Landmarks ; Double Outlet Right Ventricle/physiopathology ; Female ; Fetal Heart/abnormalities ; Fetal Heart/physiopathology ; Gestational Age ; Humans ; Image Interpretation, Computer-Assisted ; Predictive Value of Tests ; Pregnancy ; Reproducibility of Results ; Spatio-Temporal Analysis ; Young Adult
Czasopismo naukowe
Tytuł :
DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement.
Autorzy :
Cheblal A; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland; University of Basel, Faculty of Natural Sciences, 4056 Basel, Switzerland.
Challa K; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Seeber A; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland; Present address: Center for Advanced Imaging, Northwest Building, 52 Oxford St, Suite 147, Harvard University, Cambridge, MA 02138, USA.
Shimada K; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Yoshida H; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Ferreira HC; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, St Andrews KY16 9ST, UK.
Amitai A; Department of Chemical Engineering, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA; The Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
Gasser SM; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland; University of Basel, Faculty of Natural Sciences, 4056 Basel, Switzerland. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Oct 15; Vol. 80 (2), pp. 311-326.e4. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Nucleosomes/*metabolism
Saccharomyces cerevisiae/*metabolism
Bleomycin/pharmacology ; Cell Cycle ; Cell Cycle Proteins/metabolism ; Centromere/metabolism ; Chromatin/metabolism ; Chromatin Assembly and Disassembly ; Chromosomal Proteins, Non-Histone/metabolism ; DNA, Fungal/metabolism ; Histones/metabolism ; Models, Biological ; Phosphorylation ; Saccharomyces cerevisiae/cytology ; Saccharomyces cerevisiae Proteins/metabolism ; Spindle Pole Bodies/metabolism
Czasopismo naukowe
Tytuł :
Reading the epigenetic code for exchanging DNA.
Autorzy :
Biot M; Institut de Génétique Humaine, University Montpellier, Montpellier, France.; Centre National de la Recherche Scientifique, University Montpellier, Montpellier, France.
de Massy B; Institut de Génétique Humaine, University Montpellier, Montpellier, France.; Centre National de la Recherche Scientifique, University Montpellier, Montpellier, France.
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Źródło :
ELife [Elife] 2020 Sep 16; Vol. 9. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
DNA Breaks, Double-Stranded*
Histones*
Animals ; DNA ; DNA Repair ; Epigenesis, Genetic ; Male ; Meiosis ; Mice ; Reading
Czasopismo naukowe
Tytuł :
POLQ suppresses interhomolog recombination and loss of heterozygosity at targeted DNA breaks.
Autorzy :
Davis L; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195.
Khoo KJ; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195.; Department of Biochemistry, University of Washington School of Medicine, Seattle, WA 98195.
Zhang Y; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195.
Maizels N; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195; .; Department of Biochemistry, University of Washington School of Medicine, Seattle, WA 98195.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 15; Vol. 117 (37), pp. 22900-22909. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Breaks, Double-Stranded*
Recombinational DNA Repair*
DNA-Directed DNA Polymerase/*metabolism
CRISPR-Cas Systems ; Cell Line, Tumor ; DNA Breaks, Single-Stranded ; DNA End-Joining Repair ; DNA Ligases/genetics ; DNA Ligases/metabolism ; DNA-Directed DNA Polymerase/genetics ; Heterozygote ; Humans ; Loss of Heterozygosity ; Mutation ; Recombination, Genetic
Czasopismo naukowe
Tytuł :
Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break.
Autorzy :
Li K; Department of Physics, Brandeis University, Waltham, MA 02454.
Bronk G; Department of Physics, Brandeis University, Waltham, MA 02454.
Kondev J; Department of Physics, Brandeis University, Waltham, MA 02454; .
Haber JE; Department of Biology, Brandeis University, Waltham, MA 02454; .; Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21354-21363. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Breaks, Double-Stranded*
Histones/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Protein-Serine-Threonine Kinases/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Bayes Theorem ; Cell Cycle Proteins/metabolism ; Chromatin Immunoprecipitation ; Diffusion ; Intracellular Signaling Peptides and Proteins/genetics ; Phosphorylation ; Protein-Serine-Threonine Kinases/genetics ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break.
Autorzy :
Lou J; School of Physics, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Priest DG; School of Physics, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Solano A; School of Physics, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Kerjouan A; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Hinde E; School of Physics, University of Melbourne, Melbourne, Victoria, Australia. .; Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 13; Vol. 11 (1), pp. 5776. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Protein Multimerization*
Tumor Suppressor p53-Binding Protein 1/*metabolism
Cell Nucleus/metabolism ; DNA Repair ; Green Fluorescent Proteins/metabolism ; Histone Code ; Models, Biological ; Spectrometry, Fluorescence ; Time Factors
Czasopismo naukowe
Tytuł :
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.
Autorzy :
Rother MB; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Pellegrino S; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.
Smith R; Univ Rennes, CNRS, IGDR (Institut de génétique et développement de Rennes)-UMR 6290, BIOSIT-UMS3480, F-35000, Rennes, France.
Gatti M; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.
Meisenberg C; The Institute of Cancer Research, Royal Cancer Hospital, London, UK.
Wiegant WW; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Luijsterburg MS; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Imhof R; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.
Downs JA; The Institute of Cancer Research, Royal Cancer Hospital, London, UK.
Vertegaal ACO; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Huet S; Univ Rennes, CNRS, IGDR (Institut de génétique et développement de Rennes)-UMR 6290, BIOSIT-UMS3480, F-35000, Rennes, France.; Institut Universitaire de France, Paris, France.
Altmeyer M; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland. .
van Attikum H; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 13; Vol. 11 (1), pp. 5775. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
DNA Helicases/*metabolism
DNA-Binding Proteins/*metabolism
Tumor Suppressor p53-Binding Protein 1/*metabolism
Cell Line, Tumor ; Chromatin/metabolism ; DNA End-Joining Repair ; DNA Ligase ATP/metabolism ; Green Fluorescent Proteins/metabolism ; Histone Deacetylase 1/metabolism ; Humans ; Ku Autoantigen/metabolism ; Poly (ADP-Ribose) Polymerase-1 ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Mechanism of efficient double-strand break repair by a long non-coding RNA.
Autorzy :
Thapar R; Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Wang JL; Ecole Normale Supérieure, IBENS, CNRS, INSERM, PSL Research University, Paris 75005, France.
Hammel M; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA 94720, USA.
Ye R; Department of Biochemistry and Molecular Biology, Robson DNA Science Centre, Charbonneau Cancer Institute, University of Calgary, Alberta, T2N 4N1, Canada.
Liang K; Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Sun C; Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Hnizda A; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.
Liang S; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.
Maw SS; Biological Systems and Bioengineering, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Lee L; Department of Biochemistry and Molecular Biology, Robson DNA Science Centre, Charbonneau Cancer Institute, University of Calgary, Alberta, T2N 4N1, Canada.
Villarreal H; CryoEM Core at Baylor College of Medicine, Houston, Texas 77030, USA.
Forrester I; CryoEM Core at Baylor College of Medicine, Houston, Texas 77030, USA.
Fang S; Department of Biochemistry and Molecular Biology, Robson DNA Science Centre, Charbonneau Cancer Institute, University of Calgary, Alberta, T2N 4N1, Canada.
Tsai MS; Biological Systems and Bioengineering, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Blundell TL; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.
Davis AJ; Division of Molecular Radiation Biology, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Lin C; Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Lees-Miller SP; Department of Biochemistry and Molecular Biology, Robson DNA Science Centre, Charbonneau Cancer Institute, University of Calgary, Alberta, T2N 4N1, Canada.
Strick TR; Ecole Normale Supérieure, IBENS, CNRS, INSERM, PSL Research University, Paris 75005, France.; Programme 'Equipe Labellisée'', Ligue Nationale Contre le Cancer, Paris 75005, France.
Tainer JA; Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA 94720, USA.; Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Nov 04; Vol. 48 (19), pp. 10953-10972.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Breaks, Double-Stranded*
DNA End-Joining Repair*
Ku Autoantigen/*metabolism
RNA, Long Noncoding/*metabolism
DNA-Binding Proteins/metabolism ; HeLa Cells ; Humans ; Protein Binding ; Protein Multimerization
Czasopismo naukowe
Tytuł :
Canonical DNA non-homologous end-joining; capacity versus fidelity.
Autorzy :
Shibata A; Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), Gunma University, Maebashi, Japan.
Jeggo PA; Genome Damage and Stability Centre, School of Life Sciences, EastSussex, BN19RQ, UK.
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Źródło :
The British journal of radiology [Br J Radiol] 2020 Nov 01; Vol. 93 (1115), pp. 20190966. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Breaks, Double-Stranded*
DNA End-Joining Repair/*physiology
DNA Mismatch Repair/*physiology
Chromatin/physiology ; DNA/radiation effects ; G1 Phase/genetics ; G2 Phase/genetics ; Humans ; Ku Autoantigen/physiology ; Resting Phase, Cell Cycle/genetics ; Transcription Termination, Genetic/physiology ; Transcriptional Activation/physiology
Czasopismo naukowe
Tytuł :
One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks.
Autorzy :
Ensminger M; Radiation Biology and DNA Repair, Technical University of Darmstadt, 64287 Darmstadt, Germany.
Löbrich M; Radiation Biology and DNA Repair, Technical University of Darmstadt, 64287 Darmstadt, Germany.
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Źródło :
The British journal of radiology [Br J Radiol] 2020 Nov 01; Vol. 93 (1115), pp. 20191054. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Breaks, Double-Stranded*
DNA End-Joining Repair/*physiology
Gene Rearrangement/*physiology
Homologous Recombination/*physiology
DNA Breaks, Single-Stranded ; G1 Phase/genetics ; G2 Phase/genetics ; Humans
Czasopismo naukowe
Tytuł :
Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ.
Autorzy :
Yu W; Genome Integrity, Immunity and Cancer Unit, Equipe Labellisée Ligue Contre Le Cancer, Institut Pasteur, 75015, Paris, France.
Lescale C; Genome Integrity, Immunity and Cancer Unit, Equipe Labellisée Ligue Contre Le Cancer, Institut Pasteur, 75015, Paris, France.
Babin L; Genome Dynamics in the Immune System Laboratory, Equipe Labellisée Ligue Contre Le Cancer, INSERM UMR 1163, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, 75015, Paris, France.
Bedora-Faure M; Genome Integrity, Immunity and Cancer Unit, Equipe Labellisée Ligue Contre Le Cancer, Institut Pasteur, 75015, Paris, France.
Lenden-Hasse H; Genome Integrity, Immunity and Cancer Unit, Equipe Labellisée Ligue Contre Le Cancer, Institut Pasteur, 75015, Paris, France.
Baron L; Immunobiology of Infection Unit, INSERM U1221, Institut Pasteur, 75015, Paris, France.
Demangel C; Immunobiology of Infection Unit, INSERM U1221, Institut Pasteur, 75015, Paris, France.
Yelamos J; Cancer Research Program, Hospital del Mar Medical Research Institute, 08003, Barcelona, Spain.
Brunet E; Genome Dynamics in the Immune System Laboratory, Equipe Labellisée Ligue Contre Le Cancer, INSERM UMR 1163, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, 75015, Paris, France.
Deriano L; Genome Integrity, Immunity and Cancer Unit, Equipe Labellisée Ligue Contre Le Cancer, Institut Pasteur, 75015, Paris, France. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 16; Vol. 11 (1), pp. 5239. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle*
DNA Breaks, Double-Stranded*
DNA End-Joining Repair*
Animals ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; G1 Phase ; Mice ; Poly (ADP-Ribose) Polymerase-1/genetics ; Poly (ADP-Ribose) Polymerase-1/metabolism
Czasopismo naukowe
Tytuł :
Stability of double-stranded RNA in gut contents and hemolymph of Ostrinia nubilalis larvae.
Autorzy :
Cooper AMW; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA.
Yu Z; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA.
Biondi M; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA.
Song H; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA; Institute of Applied Biology, Shanxi University, Taiyuan, Shanxi 030006, China.
Silver K; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA.
Zhang J; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA; Institute of Applied Biology, Shanxi University, Taiyuan, Shanxi 030006, China.
Zhu KY; Department of Entomology, 123 Waters Hall, Kansas State University, Manhattan, KS 66506, USA. Electronic address: .
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2020 Oct; Vol. 169, pp. 104672. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome*
RNA, Double-Stranded*
Animals ; Hemolymph ; Larva ; RNA Interference
Czasopismo naukowe
Tytuł :
Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity.
Autorzy :
Janisiw E; Department of Chromosome Biology, Max Perutz Laboratories, Vienna Biocenter, University of Vienna, Vienna, Austria.; Centre for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Raices M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Balmir F; Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; AHN Center for Reproductive Medicine, AHN McCandless, Pittsburgh, PA, USA.
Paulin LF; Center for Integrative Bioinformatics Vienna (CIBIV), Max Perutz Laboratories, Medical University of Vienna, Vienna BioCenter, University of Vienna, Vienna, Austria.
Baudrimont A; Department of Chromosome Biology, Max Perutz Laboratories, Vienna Biocenter, University of Vienna, Vienna, Austria.
von Haeseler A; Center for Integrative Bioinformatics Vienna (CIBIV), Max Perutz Laboratories, Medical University of Vienna, Vienna BioCenter, University of Vienna, Vienna, Austria.; Bioinformatics and Computational Biology, Faculty of Computer Science, University of Vienna, Vienna, Austria.
Yanowitz JL; Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jantsch V; Department of Chromosome Biology, Max Perutz Laboratories, Vienna Biocenter, University of Vienna, Vienna, Austria.
Silva N; Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 25; Vol. 11 (1), pp. 4869. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Caenorhabditis elegans/*metabolism
DNA/*metabolism
DNA Repair/*physiology
Glycoside Hydrolases/*metabolism
Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Cell Nucleus/metabolism ; Germ Cells ; Glycoside Hydrolases/genetics ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Poly ADP Ribosylation ; Poly Adenosine Diphosphate Ribose/metabolism ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks.
Autorzy :
Britton S; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Equipe Labellisée Ligue contre le Cancer 2018, Toulouse, France.
Chanut P; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Equipe Labellisée Ligue contre le Cancer 2018, Toulouse, France.
Delteil C; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Equipe Labellisée Ligue contre le Cancer 2018, Toulouse, France.
Barboule N; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Equipe Labellisée Ligue contre le Cancer 2018, Toulouse, France.
Frit P; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Equipe Labellisée Ligue contre le Cancer 2018, Toulouse, France.
Calsou P; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.; Equipe Labellisée Ligue contre le Cancer 2018, Toulouse, France.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Sep 25; Vol. 48 (17), pp. 9710-9723.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Ataxia Telangiectasia Mutated Proteins/*metabolism
DNA End-Joining Repair/*physiology
DNA-Activated Protein Kinase/*metabolism
Ku Autoantigen/*metabolism
Ataxia Telangiectasia Mutated Proteins/genetics ; Camptothecin/pharmacology ; Cell Line ; DNA End-Joining Repair/drug effects ; DNA Ligase ATP/genetics ; DNA Ligase ATP/metabolism ; DNA, Single-Stranded ; DNA-Activated Protein Kinase/genetics ; Humans ; Ku Autoantigen/genetics ; MRE11 Homologue Protein/genetics ; MRE11 Homologue Protein/metabolism ; Phosphorylation ; Topoisomerase I Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Recent advances in the nucleolar responses to DNA double-strand breaks.
Autorzy :
Korsholm LM; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Gál Z; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Nieto B; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Quevedo O; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Boukoura S; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Lund CC; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
Larsen DH; Danish Cancer Society Research Center, Nucleolar Stress and Disease Group, Strandboulevarden 49, 2100 Copenhagen, Denmark.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Sep 25; Vol. 48 (17), pp. 9449-9461.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
DNA Breaks, Double-Stranded*
Cell Nucleolus/*genetics
DNA Repair/*physiology
Animals ; Antineoplastic Agents/pharmacology ; Cell Nucleolus/drug effects ; Cell Nucleolus/metabolism ; DNA, Ribosomal/genetics ; DNA, Ribosomal/metabolism ; Genomic Instability ; Homologous Recombination ; Humans ; Neoplasms/drug therapy ; Neoplasms/genetics ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Phosphoproteins/genetics ; Phosphoproteins/metabolism
Czasopismo naukowe
Tytuł :
Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break.
Autorzy :
Kaminski AM; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Dr., Bldg. 101/Rm F338, Research Triangle Park, NC, 27709, USA.
Pryor JM; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, 32-046 Lineberger Comprehensive Cancer Center, 450 West Dr., CB 7295, Chapel Hill, NC, 27599, USA.
Ramsden DA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, 32-046 Lineberger Comprehensive Cancer Center, 450 West Dr., CB 7295, Chapel Hill, NC, 27599, USA.
Kunkel TA; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Dr., Bldg. 101/Rm F338, Research Triangle Park, NC, 27709, USA.
Pedersen LC; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Dr., Bldg. 101/Rm F338, Research Triangle Park, NC, 27709, USA. .
Bebenek K; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Dr., Bldg. 101/Rm F338, Research Triangle Park, NC, 27709, USA.
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Źródło :
Nature communications [Nat Commun] 2020 Sep 22; Vol. 11 (1), pp. 4784. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Breaks, Double-Stranded*
DNA/*chemistry
DNA-Directed DNA Polymerase/*chemistry
Crystallography, X-Ray ; DNA Damage ; DNA End-Joining Repair ; DNA Ligase ATP/metabolism ; DNA Repair ; DNA-Binding Proteins/chemistry ; Humans ; Hydrogen Bonding ; Models, Molecular ; Protein Conformation
Czasopismo naukowe
Tytuł :
Closely related reovirus lab strains induce opposite expression of RIG-I/IFN-dependent versus -independent host genes, via mechanisms of slow replication versus polymorphisms in dsRNA binding σ3 respectively.
Autorzy :
Mohamed A; Department of Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada.
Konda P; Department of Pathology and Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada.
Eaton HE; Department of Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada.
Gujar S; Department of Pathology and Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada.
Smiley JR; Department of Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada.
Shmulevitz M; Department of Medical Microbiology and Immunology, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Sep 21; Vol. 16 (9), pp. e1008803. Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Polymorphism, Genetic*
Virus Replication*
Capsid Proteins/*metabolism
Interferons/*metabolism
RNA, Double-Stranded/*metabolism
RNA-Binding Proteins/*metabolism
Receptors, Retinoic Acid/*metabolism
Reoviridae Infections/*virology
Capsid Proteins/genetics ; Cytokines ; Humans ; Interferon Regulatory Factor-3/genetics ; Interferon Regulatory Factor-3/metabolism ; Orthoreovirus, Mammalian/physiology ; RNA, Double-Stranded/genetics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; RNA-Binding Proteins/genetics ; Receptors, Retinoic Acid/genetics ; Reoviridae Infections/genetics ; Reoviridae Infections/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.
Autorzy :
Woo TT; Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan.
Chuang CN; Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan.
Higashide M; Laboratory of Genome-Chromosome Functions, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Japan.
Shinohara A; Laboratory of Genome-Chromosome Functions, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Japan.
Wang TF; Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Sep 04; Vol. 48 (15), pp. 8474-8489.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Endodeoxyribonucleases/*genetics
Meiosis/*genetics
Rad51 Recombinase/*genetics
Saccharomyces cerevisiae Proteins/*genetics
DNA Damage/genetics ; DNA Repair/genetics ; DNA-Binding Proteins/genetics ; Gene Expression Regulation, Fungal/genetics ; Intracellular Signaling Peptides and Proteins/genetics ; Phosphorylation/genetics ; Proteasome Endopeptidase Complex/genetics ; Protein Domains/genetics ; Protein-Serine-Threonine Kinases/genetics ; Proteolysis ; Saccharomyces cerevisiae/genetics ; beta-Galactosidase/genetics
Czasopismo naukowe

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