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Tytuł:
Effects of different doses of esketamine intervention on postpartum depressive symptoms in cesarean section women: A randomized, double-blind, controlled clinical study.
Autorzy:
Yang SQ; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Zhou YY; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Yang ST; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Mao XY; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, China.
Chen L; Department of Anesthesiology, The Maternal and Child Health Hospital of the Hu Nan Province, Changsha, China.
Bai ZH; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Ping AQ; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Xu SY; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Li QW; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Gao K; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China.
Wang SY; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China. Electronic address: .
Duan KM; Department of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, China. Electronic address: .
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Źródło:
Journal of affective disorders [J Affect Disord] 2023 Oct 15; Vol. 339, pp. 333-341. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Depression*
Ketamine*/adverse effects
Pregnancy ; Female ; Humans ; Postpartum Period ; Cesarean Section/adverse effects ; Double-Blind Method
Czasopismo naukowe
Tytuł:
A randomized, double-blind, comparative study of the pharmacodynamics and pharmacokinetics of GP40141 (romiplostim biosimilar) and reference romiplostim in healthy male volunteers.
Autorzy:
Makarenko I; R&D Center, GEROPHARM, Saint Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'A.I. Evdokimov Moscow State University of Medicine and Dentistry' of the Ministry of Healthcare of the Russian Federation, Moscow, Russia.
Dorotenko A; R&D Center, GEROPHARM, Saint Petersburg, Russia.; Valdman Institute of Pharmacology, Pavlov First St. Petersburg State Medical University, Saint Petersburg, Russia.
Noskov S; Clinical Hospital №3, Yaroslavl, Russia.
Banko V; R&D Center, GEROPHARM, Saint Petersburg, Russia.
Saparova V; R&D Center, GEROPHARM, Saint Petersburg, Russia.; Federal State Budgetary Educational Institution of Higher Education 'A.I. Evdokimov Moscow State University of Medicine and Dentistry' of the Ministry of Healthcare of the Russian Federation, Moscow, Russia.
Khokhlov A; Federal State Budgetary Educational Institution of Higher Education, 'Yaroslavl State Medical University' of the Ministry of Health of the Russian Federation, Yaroslavl, Russia.
Zoreeva E; R&D Center, GEROPHARM, Saint Petersburg, Russia.
Nedorubov A; Institute for Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Zinnatulina B; R&D Center, GEROPHARM, Saint Petersburg, Russia.
Gefen M; R&D Center, GEROPHARM, Saint Petersburg, Russia.
Drai R; R&D Center, GEROPHARM, Saint Petersburg, Russia.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Oct; Vol. 11 (5), pp. e01125.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Biosimilar Pharmaceuticals*/adverse effects
Humans ; Male ; Double-Blind Method ; Recombinant Fusion Proteins/adverse effects ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Safety and efficacy of arimoclomol for inclusion body myositis: a multicentre, randomised, double-blind, placebo-controlled trial.
Autorzy:
Machado PM; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK. Electronic address: .
McDermott MP; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA.
Blaettler T; Orphazyme, Copenhagen, Denmark.
Sundgreen C; Orphazyme, Copenhagen, Denmark.
Amato AA; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.
Ciafaloni E; Department of Neurology, University of Rochester Medical Center, Rochester, NY, USA.
Freimer M; Department of Neurology, The Ohio State Wexner Medical Center, Columbus, OH, USA.
Gibson SB; Neuromuscular Division, University of Utah School of Medicine, Salt Lake City, UT, USA.
Jones SM; Department of Neurology, University of Virginia, Charlottesville, VA, USA.
Levine TD; Department of Neurology, HonorHealth, Phoenix, AZ, USA.
Lloyd TE; Departments of Neurology and Neuroscience, Johns Hopkins University, Baltimore, MD, USA.
Mozaffar T; Division of Neuromuscular Disorders, University of California, Irvine, Orange, CA, USA.
Shaibani AI; Nerve and Muscle Center of Texas, Baylor College of Medicine, Houston, TX, USA.
Wicklund M; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Rosholm A; Orphazyme, Copenhagen, Denmark.
Carstensen TD; Orphazyme, Copenhagen, Denmark.
Bonefeld K; Orphazyme, Copenhagen, Denmark.
Jørgensen AN; Orphazyme, Copenhagen, Denmark.
Phonekeo K; Orphazyme, Copenhagen, Denmark.
Heim AJ; Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.
Herbelin L; Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.
Barohn RJ; Department of Neurology, University of Missouri, Columbia, MO, USA.
Hanna MG; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.
Dimachkie MM; Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA. Electronic address: .
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Corporate Authors:
Arimoclomol in IBM Investigator Team of the Neuromuscular Study Group
Źródło:
The Lancet. Neurology [Lancet Neurol] 2023 Oct; Vol. 22 (10), pp. 900-911.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article
MeSH Terms:
Myositis, Inclusion Body*/drug therapy
United States ; Adult ; Humans ; Animals ; Female ; Male ; Mice ; Pilot Projects ; Double-Blind Method ; Disease Progression
Czasopismo naukowe
Tytuł:
Safety and efficacy of tamoxifen in boys with Duchenne muscular dystrophy (TAMDMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
Autorzy:
Henzi BC; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland; Department of Neuropediatrics and Muscle Disorders, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Schmidt S; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Nagy S; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland.
Rubino-Nacht D; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Schaedelin S; Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland.
Putananickal N; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Stimpson G; Developmental Neuroscience Research and Teaching Department, Faculty of Population Health Sciences, Dubowitz Neuromuscular Centre, UCL Great Ormond Street Institute of Child Health, London, UK.
Amthor H; Service de Neurologie et Réanimation Pédiatriques, APHP Paris Saclay, Hôpital Raymond Poincaré, Garches, France.
Childs AM; The Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Deconinck N; Department of Paediatric Neurology and Neuromuscular Reference Center, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium.
de Groot I; Department of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, Netherlands.
Horrocks I; Royal Hospital for Children, Glasgow, UK.
Houwen-van Opstal S; Department of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, Netherlands.
Laugel V; Department of Pediatric Neurology, Strasbourg University Hospital, Strasbourg, France.
Lopez Lobato M; Sección de Neurología Pediátrica, Hospital Universitario Virgen del Rocío, Seville, Spain.
Madruga Garrido M; Sección de Neurología Pediátrica, Hospital Universitario Virgen del Rocío, Seville, Spain.
Nascimento Osorio A; Neuromuscular Unit, Department of Neurology, Hospital Sant Joan de Déu and Center for Biomedical Research Network on Rare Diseases, ISCIII, Barcelona, Spain.
Schara-Schmidt U; Department of Pediatric Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Spinty S; Alder Hey Children's Hospital, Liverpool, UK.
von Moers A; Department of Pediatrics, DRK Kliniken Berlin Westend, Berlin, Germany.
Lawrence F; Duchenne UK, London, UK.
Hafner P; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Dorchies OM; School of Pharmaceutical Sciences and Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.
Fischer D; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel, University of Basel, Basel, Switzerland. Electronic address: .
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Corporate Authors:
North Star Consortium
Źródło:
The Lancet. Neurology [Lancet Neurol] 2023 Oct; Vol. 22 (10), pp. 890-899.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Journal Article
MeSH Terms:
Muscular Dystrophy, Duchenne*/drug therapy
Male ; Animals ; Mice ; Humans ; Double-Blind Method ; Disease Models, Animal ; Drug Repositioning ; Ethnicity
Czasopismo naukowe
Tytuł:
Efficacy and safety of lemborexant in subjects previously treated with placebo for 6 months in a randomized phase 3 study.
Autorzy:
Yardley J; Eisai Ltd., Hatfield, UK.
Inoue Y; Tokyo Medical University, Tokyo, Japan.
Pinner K; Eisai Ltd., Hatfield, UK.
Perdomo C; Eisai Inc., Nutley, NJ, USA.
Kubota N; Eisai Co., Ltd, Tokyo, Japan.
Perlis ML; Behavioral Sleep Medicine Program, Department of Psychiatry, University of Pennsylvania, PA, USA.
Moline M; Eisai Inc., Nutley, NJ, USA. Electronic address: margaret_.
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Źródło:
Sleep medicine [Sleep Med] 2023 Oct; Vol. 110, pp. 111-119. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase III; Journal Article
MeSH Terms:
Pyridines*/therapeutic use
Sleep Initiation and Maintenance Disorders*/drug therapy
Humans ; Double-Blind Method ; Sleep ; Treatment Outcome
Czasopismo naukowe
Tytuł:
The effects of cannabidiol on worry and anxiety among high trait worriers: a double-blind, randomized placebo controlled trial.
Autorzy:
Gournay LR; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA. .
Ferretti ML; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA.
Bilsky S; University of Mississippi, Oxford, USA.
Vance E; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA.
Nguyen AM; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA.
Mann E; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA.; Laureate Institute for Brain Research, Tulsa, USA.
Williams P; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA.
Leen-Feldner EW; University of Arkansas, 216 Memorial Hall, Fayetteville, AR, 72701, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Oct; Vol. 240 (10), pp. 2147-2161. Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Cannabidiol*/pharmacology
Cannabidiol*/therapeutic use
Anti-Anxiety Agents*/pharmacology
Anti-Anxiety Agents*/therapeutic use
Humans ; Anxiety/drug therapy ; Anxiety Disorders/drug therapy ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Multispecies probiotic affects fecal short-chain fatty acids in postmenopausal women with obesity: A post hoc analysis of a randomized, double-blind, placebo-controlled study.
Autorzy:
Łoniewski I; Department of Biochemical Sciences, Pomeranian Medical University in Szczecin, Szczecin, Poland; Department of Human Nutrition and Metabolomics, Pomeranian Medical University, Szczecin, Poland.
Szulińska M; Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, University of Medical Sciences in Poznań, Poznań, Poland.
Kaczmarczyk M; Sanprobi sp. z o.o. sp. k., Kurza Stopka, Szczecin, Poland.
Podsiadło K; Department of Clinical Biochemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Styburski D; Sanprobi sp. z o.o. sp. k., Kurza Stopka, Szczecin, Poland.
Skonieczna-Żydecka K; Department of Biochemical Sciences, Pomeranian Medical University in Szczecin, Szczecin, Poland. Electronic address: .
Bogdański P; Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, University of Medical Sciences in Poznań, Poznań, Poland.
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Źródło:
Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2023 Oct; Vol. 114, pp. 112109. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Postmenopause*
Probiotics*/therapeutic use
Humans ; Female ; Uric Acid ; Obesity/therapy ; Feces/chemistry ; Fatty Acids, Volatile/analysis ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Does probiotic supplementation improve quality of life in mild-to-moderately active ulcerative colitis patients in Jordan? A secondary outcome of the randomized, double-blind, placebo-controlled study.
Autorzy:
Rayyan YM; Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, The University of Jordan, Amman, Jordan. .
Agraib LM; Department of Food Science and Nutrition, Faculty of Agriculture, Jerash University, Jerash, Jordan.
Alkhatib B; Department of Clinical Nutrition and Dietetics, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan.
Yamani MI; Department of Nutrition and Food Technology, Faculty of Agriculture, The University of Jordan, Amman, Jordan.
Abu-Sneineh AT; Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, The University of Jordan, Amman, Jordan.
Tayyem RF; Department of Nutrition and Food Technology, Faculty of Agriculture, The University of Jordan, Amman, Jordan.; Department of Human Nutrition, College of Health Sciences, Qatar University, Doha, Qatar.
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Źródło:
European journal of nutrition [Eur J Nutr] 2023 Oct; Vol. 62 (7), pp. 3069-3077. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Colitis, Ulcerative*/drug therapy
COVID-19*
Probiotics*/therapeutic use
Humans ; Quality of Life ; Jordan ; Pandemics ; Bifidobacterium ; Lactobacillus ; Dietary Supplements ; Double-Blind Method ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Postoperative infusion of dexmedetomidine via intravenous patient-controlled analgesia for prevention of postoperative delirium in elderly patients undergoing surgery.
Autorzy:
Xie K; Department of Anesthesiology, Zhejiang Cancer Hospital, Research Center for Neuro-Oncology Interaction, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Chen J; Postgraduate training Base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, Zhejiang, China.
Tian L; Traditional Chinese Medicine Pharmacy, Zhejiang Hospital, Hangzhou, 310022, Zhejiang, China.
Gu F; Postgraduate training Base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, Zhejiang, China.
Pan Y; Department of Anesthesiology, Zhejiang Cancer Hospital, Research Center for Neuro-Oncology Interaction, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Huang Z; Department of Anesthesiology, Zhejiang Cancer Hospital, Research Center for Neuro-Oncology Interaction, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Fang J; Department of Anesthesiology, Zhejiang Cancer Hospital, Research Center for Neuro-Oncology Interaction, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Yu W; Department of Anesthesiology, Zhejiang Cancer Hospital, Research Center for Neuro-Oncology Interaction, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.; Postgraduate training Base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, Zhejiang, China.
Zhou H; Department of Anesthesiology, Zhejiang Cancer Hospital, Research Center for Neuro-Oncology Interaction, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China. .
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Źródło:
Aging clinical and experimental research [Aging Clin Exp Res] 2023 Oct; Vol. 35 (10), pp. 2137-2144. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Emergence Delirium*
Dexmedetomidine*/adverse effects
Aged ; Humans ; Middle Aged ; Analgesia, Patient-Controlled ; Sufentanil ; Postoperative Period ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study.
Autorzy:
Haugen ME; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway. .
Vårvik FT; Department of Sport Science and Physical Education, Faculty of Health and Sport Sciences, University of Agder, Kristiansand, Norway.; Norwegian Olympic and Paralympic Committee and Confederation of Sports, Oslo, Norway.
Grgic J; Institute for Health and Sport, Victoria University, Melbourne, Australia.
Studsrud H; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway.
Austheim E; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway.
Zimmermann EM; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway.
Falch HN; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway.
Larsen S; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway.
van den Tillaar R; Department of Sport Sciences and Physical Education, Nord University, Levanger, Norway.
Bjørnsen T; Department of Sport Science and Physical Education, Faculty of Health and Sport Sciences, University of Agder, Kristiansand, Norway.; Norwegian Olympic and Paralympic Committee and Confederation of Sports, Oslo, Norway.
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Źródło:
European journal of nutrition [Eur J Nutr] 2023 Oct; Vol. 62 (7), pp. 2963-2975. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Resistance Training*
Performance-Enhancing Substances*/pharmacology
Male ; Female ; Humans ; Caffeine/pharmacology ; Cross-Over Studies ; Physical Endurance ; Double-Blind Method ; Muscle Strength ; Eating
Czasopismo naukowe
Tytuł:
Efficacy and safety of clonidine for the treatment of impulse control disorder in Parkinson's disease: a multicenter, parallel, randomised, double-blind, Phase 2b Clinical trial.
Autorzy:
Laurencin C; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France. .; Lyon Neuroscience Research Centre, INSERM, University of Lyon, 69622, Lyon, France. .
Timestit N; Department of Biostatistics, University Hospital of Lyon, Lyon, France.
Marques A; Department of Neurology, Clermont-Ferrand University Hospital, NS-Park/F-CRIN, Clermont-Ferrand, France.
Duchez DD; Department of Neurology, University Hospital of Saint-Etienne, Saint-Etienne, France.
Giordana C; Department of Neurology, University Hospital of Nice, NS-Park/F-CRIN, Nice, France.
Meoni S; Movement Disorders Unit, Department of Neurology, University Hospital of Grenoble, NS-Park/F-CRIN, Grenoble, France.
Huddlestone M; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France.
Danaila T; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France.
Anheim M; Department of Neurology, Strasbourg University Hospital, Strasbourg, France.; Institut de Génétique Et de Biologie Moléculaire Et Cellulaire (IGBMC), INSERM-U964/CNRS, UMR7104/Strasbourg University, Illkirch, France.; Centre de Référence Des Maladies Neurogénétiques Rares, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France.
Klinger H; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France.
Vidal T; Department of Neurology, Clermont-Ferrand University Hospital, NS-Park/F-CRIN, Clermont-Ferrand, France.
Fatisson M; Department of Neurology, University Hospital of Saint-Etienne, Saint-Etienne, France.
Caire C; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France.
Nourredine M; Department of Biostatistics, University Hospital of Lyon, Lyon, France.; Pharmacotoxicology Laboratory, Department of Clinical Research and Epidemiology, University Hospital of Lyon, Lyon, France.
Boulinguez P; Lyon Neuroscience Research Centre, INSERM, University of Lyon, 69622, Lyon, France.
Dhelens C; Pharmacy, FRIPHARM, Edouard Herriot Hospital, Lyon University Hospital, Lyon, France.
Ballanger B; Lyon Neuroscience Research Centre, INSERM, University of Lyon, 69622, Lyon, France.
Prange S; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France.; Marc Jeannerod Cognitive Neuroscience Institute, CNRS, UMR 5229, Bron, France.; Faculté de Medecine Et de Maieutique Lyon Sud Charles Mérieux, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France.
Bin S; Public Health Center, Research and Clinical Epidemiology, University Hospital of Lyon, Lyon, France.
Thobois S; Department of Neurology C, Expert Parkinson Centre, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C - Hospices Civils de Lyon, NS-Park/F-CRIN, 69677, Bron, France.; Marc Jeannerod Cognitive Neuroscience Institute, CNRS, UMR 5229, Bron, France.; Faculté de Medecine Et de Maieutique Lyon Sud Charles Mérieux, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France.
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Źródło:
Journal of neurology [J Neurol] 2023 Oct; Vol. 270 (10), pp. 4851-4859. Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article
MeSH Terms:
Parkinson Disease*/complications
Parkinson Disease*/drug therapy
Parkinson Disease*/diagnosis
Disruptive, Impulse Control, and Conduct Disorders*/drug therapy
Disruptive, Impulse Control, and Conduct Disorders*/etiology
Humans ; Clonidine/adverse effects ; Impulsive Behavior ; Double-Blind Method ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Efficacy of metformin vs. doxycycline in treating acne vulgaris: An assessor-blinded, add-on, randomized, controlled clinical trial.
Autorzy:
Sadati MS; Molecular Dermatology Research Center, Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.
Yazdanpanah N; Molecular Dermatology Research Center, Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahriarirad R; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Javaheri R; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Parvizi MM; Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2023 Oct; Vol. 22 (10), pp. 2816-2823. Date of Electronic Publication: 2023 May 02.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Metformin*/therapeutic use
Acne Vulgaris*/drug therapy
Acne Vulgaris*/pathology
Humans ; Doxycycline/therapeutic use ; Insulin-Like Growth Factor I ; Immunoglobulin A/therapeutic use ; Treatment Outcome ; Gels ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Perilesional injections of human platelet lysate versus platelet poor plasma for the treatment of diabetic foot ulcers: A double-blinded prospective clinical trial.
Autorzy:
Alhawari H; School of Medicine, Department of Internal Medicine, The University of Jordan, Amman, Jordan.
Jafar H; Cell Therapy Center, The University of Jordan, Amman, Jordan.; Department of Anatomy and Histology, School of Medicine, The University of Jordan, Amman, Jordan.
Al Soudi M; School of Medicine, University of Jordan, Amman, Jordan.
Ameereh LA; Cell Therapy Center, The University of Jordan, Amman, Jordan.
Fawaris M; Cell Therapy Center, The University of Jordan, Amman, Jordan.
Saleh M; Cell Therapy Center, The University of Jordan, Amman, Jordan.
Aladwan S; Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan.
Younes N; Department of Surgery, School of Medicine, The University of Jordan, Amman, Jordan.
Awidi A; Cell Therapy Center, The University of Jordan, Amman, Jordan.; Department of Internal Medicine Hematology-Oncology, School of Medicine, The University of Jordan, Amman, Jordan.; Department of Hematology-Oncology, Jordan University Hospital, Amman, Jordan.
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Źródło:
International wound journal [Int Wound J] 2023 Oct; Vol. 20 (8), pp. 3116-3122. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Diabetic Foot*/drug therapy
Platelet-Rich Plasma*
Diabetes Mellitus*
Humans ; Prospective Studies ; Wound Healing ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Pharmacokinetics, pharmacodynamics, safety and tolerability of FTP-198, a novel, selective Autotaxin inhibitor, in healthy subjects: A phase I randomized placebo-controlled trial.
Autorzy:
Yang L; Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, Sichuan, 610044, China; Clinical Trial Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, Sichuan, 610044, China.
Shu P; Clinical Trial Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, Sichuan, 610044, China.
Wu N; Haisco Pharmaceutical Group Co., LtPd., Chengdu, China.
Hu M; Haisco Pharmaceutical Group Co., LtPd., Chengdu, China.
Luo Z; Clinical Trial Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, Sichuan, 610044, China. Electronic address: .
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Źródło:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2023 Oct 01; Vol. 189, pp. 106552. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Idiopathic Pulmonary Fibrosis*/drug therapy
Humans ; Healthy Volunteers ; Area Under Curve ; Administration, Oral ; Half-Life ; Double-Blind Method ; Dose-Response Relationship, Drug
Czasopismo naukowe
Tytuł:
White matter predicts tDCS antidepressant effects in a sham-controlled clinical trial study.
Autorzy:
Zanao TA; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Luethi MS; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Goerigk S; Department and Institute of Psychiatry, Faculdade de Medicina da Universidade de São Paulo, Laboratory of Neurosciences LIM-27), São Paulo, Brazil.; Department of Psychological Methodology and Assessment, LMU Munich, Munich, Germany.
Suen P; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Diaz AP; Hochschule Fresenius, University of Applied Sciences, Munich, Germany.
Soares JC; Hochschule Fresenius, University of Applied Sciences, Munich, Germany.
Brunoni AR; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. .; Hospital Universitário, Departamento de Clínica Médica, Faculdade de Medicina da USP, São Paulo, Brazil. .
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Źródło:
European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2023 Oct; Vol. 273 (7), pp. 1421-1431. Date of Electronic Publication: 2022 Nov 07.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Transcranial Direct Current Stimulation*/methods
White Matter*/diagnostic imaging
Depressive Disorder, Major*/therapy
Female ; Humans ; Adult ; Diffusion Tensor Imaging ; Escitalopram ; Antidepressive Agents/therapeutic use ; Treatment Outcome ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Olanzapine as an add-on, pre-operative anti-emetic drug for postoperative nausea or vomiting: a randomised controlled trial.
Autorzy:
Grigio TR; Postgraduate Program of Anesthesiology, Surgical Sciences and Perioperative Medicine, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, Brazil.; Department of Anesthesiology, Pain Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Timmerman H; Department of Anesthesiology, Pain Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Martins JVB; Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, Brazil.
Slullitel A; Postgraduate Program of Anesthesiology, Surgical Sciences and Perioperative Medicine, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, Brazil.
Wolff AP; Department of Anesthesiology, Pain Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Sousa AM; Postgraduate Program of Anesthesiology, Surgical Sciences and Perioperative Medicine, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, Brazil.
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Źródło:
Anaesthesia [Anaesthesia] 2023 Oct; Vol. 78 (10), pp. 1206-1214. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Antiemetics*/therapeutic use
Antineoplastic Agents*
Humans ; Postoperative Nausea and Vomiting/chemically induced ; Olanzapine/adverse effects ; Ondansetron/adverse effects ; Dexamethasone ; Double-Blind Method
Czasopismo naukowe
Tytuł:
A Phase III Study of Bumetanide Oral Liquid Formulation for the Treatment of Children and Adolescents Aged Between 7 and 17 Years with Autism Spectrum Disorder (SIGN 1 Trial): Participant Baseline Characteristics.
Autorzy:
Georgoula C; ReCognition Health, London, UK.
Ferrin M; ReCognition Health, London, UK.
Pietraszczyk-Kedziora B; Child and Adolescent Psychiatry Unit, Niepubliczny Zakład Opieki Zdrowotnej Gdańskie Centrum Zdrowia, Gdańsk, Poland.
Hervas A; Child and Adolescent Mental Health Unit, Hospital Universitari Mútua de Terrassa, and Global Institute of Neurodevelopment Integrated Care (IGAIN), Barcelona, Spain.
Marret S; Department of Neonatal Pediatrics, Intensive Care, and Neuropediatrics, Rouen University Hospital and INSERM U 1245 Team 4 Neovasc, School of Medicine, Normandy University, Rouen, France.
Oliveira G; Neurodevelopmental and Autism Unit From Child Developmental Center and Centro de Investigação e Formação Clínica, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.; Faculty of Medicine, University Clinic of Pediatrics, University of Coimbra, Coimbra, Portugal.
Rosier A; Department of Neonatal Pediatrics, CHU de Rouen and CHU le Rouvray, Sotteville les Rouen, France.
Crutel V; Neuro Inflammation Therapeutic Area, Institut de Recherches Internationales Servier, 50 Rue Carnot, 92284, Suresnes CEDEX, France.
Besse E; Neuro Inflammation Therapeutic Area, Institut de Recherches Internationales Servier, 50 Rue Carnot, 92284, Suresnes CEDEX, France.
Severo CA; Neuro Inflammation Therapeutic Area, Institut de Recherches Internationales Servier, 50 Rue Carnot, 92284, Suresnes CEDEX, France. .
Ravel D; Neurochlore, Marseille, France.
Fuentes J; Child & Adolescent Psychiatry Service, Policlínica Gipuzkoa and Gipuzkoa Autism Society (GAUTENA), Donostia/San Sebastián, Spain.
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Źródło:
Child psychiatry and human development [Child Psychiatry Hum Dev] 2023 Oct; Vol. 54 (5), pp. 1360-1372. Date of Electronic Publication: 2022 Mar 16.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase III; Journal Article
MeSH Terms:
Autism Spectrum Disorder*/drug therapy
Autistic Disorder*/diagnosis
Humans ; Child ; Male ; Adolescent ; Female ; Bumetanide/adverse effects ; Double-Blind Method ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Comparison of the effects of a phospholipid-enhanced fish oil versus krill oil product on plasma levels of eicosapentaenoic and docosahexaenoic acids after acute administration: A randomized, double-blind, crossover study.
Autorzy:
Guarneiri LL; Midwest Biomedical Research, Addison, Illinois, USA.
Wilcox ML; Midwest Biomedical Research, Addison, Illinois, USA.
Maki KC; Midwest Biomedical Research, Addison, Illinois, USA; Indiana Department of Applied Health Science, University School of Public Health-Bloomington, Bloomington, Indiana, USA. Electronic address: .
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Źródło:
Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2023 Oct; Vol. 114, pp. 112090. Date of Electronic Publication: 2023 May 29.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Fish Oils*
Euphausiacea*
Male ; Adult ; Animals ; Humans ; Female ; Docosahexaenoic Acids ; Phospholipids ; Cross-Over Studies ; Eicosapentaenoic Acid ; Double-Blind Method
Czasopismo naukowe
Tytuł:
An observational study of abrocitinib in adults with moderate-to-severe atopic dermatitis after switching from dupilumab.
Autorzy:
Tong Z; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Zhang Y; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Zhou K; Department of Dermatology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
Zou Y; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China; Allergy Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Wu Z; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Chen J; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Zhuang Z; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Zhao Y; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Gong T; Central Laboratory, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. Electronic address: .
Ji C; Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China; Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, Fuzhou, Fujian, China. Electronic address: .
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Źródło:
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2023 Oct; Vol. 89 (4), pp. 826-828. Date of Electronic Publication: 2023 Jun 10.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dermatitis, Atopic*/drug therapy
Humans ; Adult ; Antibodies, Monoclonal, Humanized/adverse effects ; Pyrimidines ; Treatment Outcome ; Severity of Illness Index ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies.
Autorzy:
Del Rosso J; JDR Dermatology Research, Las Vegas, Nevada; Advanced Dermatology and Cosmetic Surgery, Maitland, Florida; Touro University Nevada, Henderson, Nevada. Electronic address: .
Sugarman J; University of California-San Francisco, San Francisco, California.
Green L; Department of Dermatology, George Washington University School of Medicine, Washington, District of Columbia.
Lain T; Sanova Dermatology, Austin, Texas.
Levy-Hacham O; Sol-Gel Technologies, Ltd, Ness Ziona, Israel.
Mizrahi R; Sol-Gel Technologies, Ltd, Ness Ziona, Israel.
Gold LS; Henry Ford Health System, Detroit, Michigan.
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Źródło:
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2023 Oct; Vol. 89 (4), pp. 719-727. Date of Electronic Publication: 2023 Jun 24.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Acne Vulgaris*/drug therapy
Acne Vulgaris*/chemically induced
Dermatologic Agents*/adverse effects
Child ; Humans ; Administration, Cutaneous ; Benzoyl Peroxide/adverse effects ; Double-Blind Method ; Drug Combinations ; Emollients/adverse effects ; Immunoglobulin A ; Treatment Outcome ; Tretinoin
Czasopismo naukowe

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