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Tytuł:
Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants.
Autorzy:
Perera V; Bristol Myers Squibb, Princeton, NJ, USA. .
Wang Z; Bristol Myers Squibb, Princeton, NJ, USA.
Lubin S; Bristol Myers Squibb, Princeton, NJ, USA.
Ueno T; Bristol-Myers Squibb K.K., Tokyo, Japan.
Shiozaki T; Bristol-Myers Squibb K.K., Tokyo, Japan.
Chen W; Bristol Myers Squibb, Princeton, NJ, USA.
Xu X; Bristol Myers Squibb, Princeton, NJ, USA.
Seiffert D; Bristol Myers Squibb, Princeton, NJ, USA.
DeSouza M; Bristol Myers Squibb, Princeton, NJ, USA.
Murthy B; Bristol Myers Squibb, Princeton, NJ, USA.
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 25; Vol. 12 (1), pp. 5165. Date of Electronic Publication: 2022 Mar 25.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Double-Blind Method*
Administration, Oral ; Area Under Curve ; Dose-Response Relationship, Drug ; Healthy Volunteers ; Humans ; Japan ; Partial Thromboplastin Time
Czasopismo naukowe
Tytuł:
Methylphenidate remediates aberrant brain network dynamics in children with attention-deficit/hyperactivity disorder: A randomized controlled trial.
Autorzy:
Mizuno Y; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA; Research Center for Child Mental Development, University of Fukui, Fukui, 910-1193, Japan; Division of Developmental Higher Brain Functions, United Graduate School of Child Development, University of Fukui, Fukui, 910-1193, Japan; Department of Child and Adolescent Psychological Medicine, University of Fukui Hospital, Fukui, 910-1193, Japan. Electronic address: .
Cai W; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94304, USA; Maternal & Child Health Research Institute, Stanford University, Stanford, CA 94304, USA.
Supekar K; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94304, USA; Maternal & Child Health Research Institute, Stanford University, Stanford, CA 94304, USA.
Makita K; Research Center for Child Mental Development, University of Fukui, Fukui, 910-1193, Japan; Division of Developmental Higher Brain Functions, United Graduate School of Child Development, University of Fukui, Fukui, 910-1193, Japan.
Takiguchi S; Division of Developmental Higher Brain Functions, United Graduate School of Child Development, University of Fukui, Fukui, 910-1193, Japan; Department of Child and Adolescent Psychological Medicine, University of Fukui Hospital, Fukui, 910-1193, Japan.
Tomoda A; Research Center for Child Mental Development, University of Fukui, Fukui, 910-1193, Japan; Division of Developmental Higher Brain Functions, United Graduate School of Child Development, University of Fukui, Fukui, 910-1193, Japan; Department of Child and Adolescent Psychological Medicine, University of Fukui Hospital, Fukui, 910-1193, Japan. Electronic address: .
Menon V; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94304, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94304, USA; Maternal & Child Health Research Institute, Stanford University, Stanford, CA 94304, USA.
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Źródło:
NeuroImage [Neuroimage] 2022 Aug 15; Vol. 257, pp. 119332. Date of Electronic Publication: 2022 May 28.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Attention Deficit Disorder with Hyperactivity*/diagnostic imaging
Attention Deficit Disorder with Hyperactivity*/drug therapy
Central Nervous System Stimulants*/pharmacology
Methylphenidate*
Brain ; Child ; Double-Blind Method ; Humans ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł:
Serum phosphopeptide profiling for colorectal cancer diagnosis using liquid chromatography-mass spectrometry.
Autorzy:
Zhai G; Beijing National Laboratory for Molecular Sciences; National Centre for Mass Spectrometry in Beijing; CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; Department of Biochemistry and Molecular Biology; Tianjin Key Laboratory of Medical Epigenetics, Tianjin Medical University, Tianjin, China.
Yang L; Cancer Research Centre, Tumour Hospital Affiliated to Nantong University, Nantong, Jiangsu, China.
Luo Q; Beijing National Laboratory for Molecular Sciences; National Centre for Mass Spectrometry in Beijing; CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Science, Beijing, China.
Wu K; Beijing National Laboratory for Molecular Sciences; National Centre for Mass Spectrometry in Beijing; CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Zhao Y; Beijing National Laboratory for Molecular Sciences; National Centre for Mass Spectrometry in Beijing; CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Wang F; Beijing National Laboratory for Molecular Sciences; National Centre for Mass Spectrometry in Beijing; CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Science, Beijing, China.; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
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Źródło:
Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2022 Aug 15; Vol. 36 (15), pp. e9316.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Colorectal Neoplasms*/diagnosis
Phosphopeptides*/chemistry
Chromatography, Liquid/methods ; Double-Blind Method ; Humans ; Mass Spectrometry/methods ; Silicon Dioxide
Czasopismo naukowe
Tytuł:
A randomized, double-blind, placebo-controlled 12-week trial of infliximab in patients with juvenile-onset spondyloarthritis.
Autorzy:
Burgos-Vargas R; Department of Rheumatology, Hospital General de Mexico Dr. Eduardo Liceaga, Mexico City, Mexico.; Faculty of Medicine, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Loyola-Sanchez A; Division of Physical Medicine and Rehabilitation, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada. .; Department of Clinical Neurosciences, Alberta Health Services, Edmonton, Canada. .
Ramiro S; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Rheumatology, Zuyderland Medical Center, Heerlen, The Netherlands.
Reding-Bernal A; Research Division, Hospital General de Mexico Dr. Eduardo Liceaga, Mexico City, Mexico.
Alvarez-Hernandez E; Department of Rheumatology, Hospital General de Mexico Dr. Eduardo Liceaga, Mexico City, Mexico.
van der Heijde D; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
Vázquez-Mellado J; Department of Rheumatology, Hospital General de Mexico Dr. Eduardo Liceaga, Mexico City, Mexico.; Faculty of Medicine, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
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Źródło:
Arthritis research & therapy [Arthritis Res Ther] 2022 Aug 08; Vol. 24 (1), pp. 187. Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Antirheumatic Agents*
Arthritis, Juvenile*/drug therapy
Spondylarthritis*/drug therapy
Spondylitis, Ankylosing*/drug therapy
Adolescent ; C-Reactive Protein ; Child ; Double-Blind Method ; Humans ; Infliximab/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł:
The effects of synbiotic and/or vitamin D supplementation on gut-muscle axis in overweight and obese women: a study protocol for a double-blind, randomized, placebo-controlled trial.
Autorzy:
Jamshidi S; Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Hemat expressway, P.O.BOX: 1449614535, Tehran, Iran.
Masoumi SJ; Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Abiri B; Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Vafa M; Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Hemat expressway, P.O.BOX: 1449614535, Tehran, Iran. .
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Źródło:
Trials [Trials] 2022 Aug 04; Vol. 23 (1), pp. 631. Date of Electronic Publication: 2022 Aug 04.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Obesity*/therapy
Overweight*/therapy
Sarcopenia*/diagnosis
Synbiotics*
Body Composition ; Dietary Supplements ; Double-Blind Method ; Female ; Gastrointestinal Microbiome ; Humans ; Iran ; Middle Aged ; Muscle Strength ; Muscles ; Randomized Controlled Trials as Topic ; Vitamin D/therapeutic use ; Vitamins
Czasopismo naukowe
Tytuł:
Effects of Sodium Benzoate, a D-Amino Acid Oxidase Inhibitor, on Perceived Stress and Cognitive Function Among Patients With Late-Life Depression: A Randomized, Double-Blind, Sertraline- and Placebo-Controlled Trial.
Autorzy:
Lin CH; Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wang SH; Department of Occupational Safety and Health.
Lane HY; Department of Psychiatry and Brain Disease Research Center, China Medical University Hospital, Taichung, Taiwan.; Department of Psychology, College of Medical and Health Sciences, Asia University, Taichung, Taiwan.
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Źródło:
The international journal of neuropsychopharmacology [Int J Neuropsychopharmacol] 2022 Aug 04; Vol. 25 (7), pp. 545-555.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Cognition*
Depressive Disorder, Major*/drug therapy
Sertraline*/therapeutic use
Sodium Benzoate*/therapeutic use
Stress, Psychological*
Aged ; Double-Blind Method ; Humans ; Middle Aged ; Oxidoreductases/antagonists & inhibitors ; Psychiatric Status Rating Scales ; Receptors, N-Methyl-D-Aspartate ; Serotonin Uptake Inhibitors/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Moderate sedation with single-dose remimazolam tosilate in elderly male patients undergoing transurethral resection of the prostate with spinal anesthesia: a prospective, single-arm, single-centre clinical trial.
Autorzy:
Zhao TY; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China.
Chen D; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China.
Sun H; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China. .
Xu ZX; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China.
Lyu S; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China.
Wang T; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China.
Liu LL; The Second Affiliated Hospital of Hainan Medical University, Hai Kou, China.
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Źródło:
BMC anesthesiology [BMC Anesthesiol] 2022 Aug 04; Vol. 22 (1), pp. 247. Date of Electronic Publication: 2022 Aug 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anesthesia, Spinal*
Transurethral Resection of Prostate*
Aged ; Aged, 80 and over ; Benzodiazepines ; Conscious Sedation/methods ; Dose-Response Relationship, Drug ; Double-Blind Method ; Humans ; Hypnotics and Sedatives ; Male ; Prospective Studies
Czasopismo naukowe
Tytuł:
A double-blind, randomised cross-over study to evaluate the absorption of a commercially available Ginkgo biloba extract compared to the liposomal extract Ginkgosome.
Autorzy:
Briskey D; RDC Clinical, Newstead, Brisbane, QLD, Australia.; School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, QLD, Australia.
Rao A; RDC Clinical, Newstead, Brisbane, QLD, Australia. .
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Źródło:
BMC complementary medicine and therapies [BMC Complement Med Ther] 2022 Aug 03; Vol. 22 (1), pp. 206. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Ginkgo biloba*
Plant Extracts*
Cross-Over Studies ; Double-Blind Method ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł:
Oral lactase for infantile colic: a randomized double-blind placebo-controlled trial.
Autorzy:
Narang M; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University College of Medical Sciences (University of Delhi) and Guru Teg Bahadur Hospital, Delhi, India. manish_.
Shah D; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University College of Medical Sciences (University of Delhi) and Guru Teg Bahadur Hospital, Delhi, India.
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Źródło:
BMC pediatrics [BMC Pediatr] 2022 Aug 03; Vol. 22 (1), pp. 468. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Colic*/drug therapy
Child ; Crying ; Double-Blind Method ; Female ; Humans ; Infant ; Lactase/therapeutic use ; Parents
Czasopismo naukowe
Tytuł:
Safety and tolerance assessment of milk fat globule membrane-enriched infant formulas in healthy term Chinese infants: a randomised multicenter controlled trial.
Autorzy:
Jiang B; Maternal &, Child Health Hospital of Fuzhou, Fuzhou, 350005, China.; School of Medicine, Xiamen University, Xiamen City, 361005, China.
Xia Y; Maternal &, Child Health Hospital of Fuzhou, Fuzhou, 350005, China.; School of Medicine, Xiamen University, Xiamen City, 361005, China.
Zhou L; School of Medicine, Xiamen University, Xiamen City, 361005, China.
Liang X; Maternal &, Child Health Hospital of Fuzhou, Fuzhou, 350005, China.
Chen X; Maternal &, Child Health Hospital of Fuqing, Fuqing, 350300, China.
Chen M; Changle Hospital, Changle, 350200, China.
Li X; Second Hospital of Fuzhou, Fuzhou, 350007, China.
Lin S; Maternal &, Child Health Hospital of Fuzhou, Fuzhou, 350005, China.
Zhang N; Maternal &, Child Health Hospital of Fuzhou, Fuzhou, 350005, China.
Zheng L; Maternal &, Child Health Hospital of Fuqing, Fuqing, 350300, China.
Tao M; Maternal &, Child Health Hospital of Fuzhou, Fuzhou, 350005, China.
Petocz P; Macquarie University, Sydney, NSW, 2109, Australia.
Gallier S; Fonterra Co-Operative Group Limited, Wellington, New Zealand.
Rowan A; Fonterra Co-Operative Group Limited, Wellington, New Zealand.
Wang B; School of Medicine, Xiamen University, Xiamen City, 361005, China. .
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Źródło:
BMC pediatrics [BMC Pediatr] 2022 Aug 03; Vol. 22 (1), pp. 465. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Glycolipids*
Infant Formula*
Breast Feeding ; China ; Double-Blind Method ; Female ; Glycoproteins ; Humans ; Infant ; Infant, Newborn ; Lipid Droplets ; Milk, Human ; Prospective Studies
Czasopismo naukowe
Tytuł:
Electrochemical Detection of a Few Copies of Unamplified SARS-CoV-2 Nucleic Acids by a Self-Actuated Molecular System.
Autorzy:
Ji D; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Guo M; Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Wu Y; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Liu W; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Luo S; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Wang X; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Kang H; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Chen Y; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Dai C; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Kong D; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Ma H; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
Liu Y; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.; Institute of Chemistry, Chinese Academy of Science, Beijing 100190, China.
Wei D; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.; Laboratory of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.
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Źródło:
Journal of the American Chemical Society [J Am Chem Soc] 2022 Aug 03; Vol. 144 (30), pp. 13526-13537. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Biosensing Techniques*/methods
COVID-19*/diagnosis
Nucleic Acids*
Double-Blind Method ; Humans ; Nasopharynx ; SARS-CoV-2/genetics
Czasopismo naukowe
Tytuł:
Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study.
Autorzy:
Cavanna F; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina.; Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI), Montañeses 2325, C1428 CABA, Buenos Aires, Argentina.
Muller S; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina.
de la Fuente LA; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina.; Institute of Cognitive and Translational Neuroscience, INECO Foundation, Favaloro University, Buenos Aires, Argentina.
Zamberlan F; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina.; Department of Cognitive Science and Artificial Intelligence, Tilburg University, Tilburg, the Netherlands.
Palmucci M; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina.
Janeckova L; Forensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Prague, Czech Republic.
Kuchar M; Forensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Prague, Czech Republic.; Department of Experimental Neurobiology, National Institute of Mental Health, Klecany, Czech Republic.
Pallavicini C; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina.; Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI), Montañeses 2325, C1428 CABA, Buenos Aires, Argentina.
Tagliazucchi E; Departamento de Física, Universidad de Buenos Aires and Instituto de Física de Buenos Aires (IFIBA - CONICET), Pabellón I, Ciudad Universitaria (1428), CABA, Buenos Aires, Argentina. .; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Chile. .
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Źródło:
Translational psychiatry [Transl Psychiatry] 2022 Aug 02; Vol. 12 (1), pp. 307. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Agaricales*
Hallucinogens*/pharmacology
Double-Blind Method ; Humans ; Motivation ; Psilocybin/pharmacology
Czasopismo naukowe
Tytuł:
Noradrenergic Add-on Therapy with Extended-Release Guanfacine in Alzheimer's Disease (NorAD): study protocol for a randomised clinical trial and COVID-19 amendments.
Autorzy:
Hoang K; Department of Brain Sciences, Imperial College London, London, UK. .; Imperial College Healthcare NHS Trust, London, UK. .
Watt H; Department of Public Health and Primary Care, Imperial College London, London, UK.
Golemme M; UK Dementia Research Institute Care Research and Technology Centre, Imperial College London and the University of Surrey, London, UK.
Perry RJ; Department of Brain Sciences, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.
Ritchie C; Edinburgh Dementia Prevention and Centre for Clinical Brain Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.
Wilson D; UK Dementia Research Institute Care Research and Technology Centre, Imperial College London and the University of Surrey, London, UK.
Pickett J; Department of Brain Sciences, Imperial College London, London, UK.
Fox C; Norwich Medical School, University of East Anglia, Norfolk, UK.
Howard R; Division of Psychiatry, University College London, Maple House 149 Tottenham Court Road, London, W1T 7NF, UK.
Malhotra PA; Department of Brain Sciences, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.; UK Dementia Research Institute Care Research and Technology Centre, Imperial College London and the University of Surrey, London, UK.
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Źródło:
Trials [Trials] 2022 Aug 01; Vol. 23 (1), pp. 623. Date of Electronic Publication: 2022 Aug 01.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Alzheimer Disease*/diagnosis
Alzheimer Disease*/drug therapy
Attention Deficit Disorder with Hyperactivity*/diagnosis
COVID-19*
Activities of Daily Living ; Cholinesterase Inhibitors/therapeutic use ; Clinical Trials, Phase III as Topic ; Delayed-Action Preparations/therapeutic use ; Double-Blind Method ; Guanfacine/adverse effects ; Humans ; Randomized Controlled Trials as Topic ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Effects of subanaesthetic S-ketamine on postoperative delirium and cognitive function in elderly patients undergoing non-cardiac thoracic surgery: a protocol for a randomised, double-blinded, placebo-controlled and positive-controlled, non-inferiority trial (SKED trial).
Autorzy:
Wei W; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhang A; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Liu L; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zheng X; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Tang C; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhou M; Department of Thoracic Surgery, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Gu Y; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China.
Yao Y; Department of Anesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China .
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Źródło:
BMJ open [BMJ Open] 2022 Aug 01; Vol. 12 (8), pp. e061535. Date of Electronic Publication: 2022 Aug 01.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Delirium*/diagnosis
Delirium*/etiology
Delirium*/prevention & control
Dexmedetomidine*/therapeutic use
Thoracic Surgery*
Aged ; Cognition ; Double-Blind Method ; Equivalence Trials as Topic ; Humans ; Ketamine ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
Effects of liraglutide on gastrointestinal functions and weight in obesity: A randomized clinical and pharmacogenomic trial.
Autorzy:
Maselli D; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Atieh J; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Clark MM; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA.
Eckert D; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Taylor A; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Carlson P; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Burton DD; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Busciglio I; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Harmsen WS; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Vella A; Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.
Acosta A; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Camilleri M; Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
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Źródło:
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2022 Aug; Vol. 30 (8), pp. 1608-1620.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:
Liraglutide*/pharmacology
Liraglutide*/therapeutic use
Pharmacogenetics*
Adult ; Double-Blind Method ; Glucagon-Like Peptide 1/therapeutic use ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/genetics ; Glucagon-Like Peptide-1 Receptor/therapeutic use ; Humans ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Obesity/complications ; Obesity/drug therapy ; Obesity/genetics ; Weight Loss/genetics
Czasopismo naukowe
Tytuł:
Acute effect of coffee on arterial stiffness and endothelial function in overweight and obese individuals: A randomized clinical trial.
Autorzy:
Pavão TP; Postgraduate Program in Gerontology at Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Chemello D; Postgraduate Program in Gerontology at Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil; Department of Clinical Medicine, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Ferigollo A; Postgraduate Program in Gerontology at Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Saffi MAL; Cardiology Division - Hospital de Clínicas de Porto (HCPA), Porto Alegre, RS, Brazil.
Moresco RN; Department of Clinical and Toxicological Analysis, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil; Postgraduate Program in Pharmaceutical Sciences at Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Stein CDS; Postgraduate Program in Pharmaceutical Sciences at Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Emanuelli T; Department of Technology and Food Science, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Somacal S; Department of Technology and Food Science, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Moriguchi EH; Department of Internal Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Brazil.
Badimon L; Cardiovascular Research Center at Hospital Santa Creu and San Pau, Spain.
Chagas P; Postgraduate Program in Gerontology at Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil; Department of Food and Nutrition, Universidade Federal de Santa Maria (UFSM), Palmeira das Missões, RS, Brazil. Electronic address: .
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Źródło:
Clinical nutrition ESPEN [Clin Nutr ESPEN] 2022 Aug; Vol. 50, pp. 33-40. Date of Electronic Publication: 2022 May 14.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Coffee*
Vascular Stiffness*
Caffeine/pharmacology ; Double-Blind Method ; Endothelium, Vascular ; Female ; Humans ; Male ; Obesity ; Overweight ; Pulse Wave Analysis
Czasopismo naukowe
Tytuł:
Transcranial direct current stimulation of the frontal-parietal-temporal brain areas reduces cigarette consumption in abstinent heroin users.
Autorzy:
Meng Z; Shenzhen Key Laboratory of Drug Addiction, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518000, China; CAS Key Laboratory of Brain Connectome and Manipulation, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Shenzhen-Hong Kong Institute of Brain Sciences-Shenzhen Fundamental Research, Institutions, Shenzhen, 518000, China. Electronic address: .
Li Q; Shenzhen Key Laboratory of Drug Addiction, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518000, China; Medical School, Kunming University of Science and Technology, Kunming, China.
Ma Y; Medical School, Kunming University of Science and Technology, Kunming, China; Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Liu C; Shenzhen Key Laboratory of Viral Vectors for Biomedicine, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518000, China; CAS Key Laboratory of Brain Connectome and Manipulation, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Shenzhen-Hong Kong Institute of Brain Sciences-Shenzhen Fundamental Research, Institutions, Shenzhen, 518000, China. Electronic address: .
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Źródło:
Journal of psychiatric research [J Psychiatr Res] 2022 Aug; Vol. 152, pp. 321-325. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Heroin Dependence*/therapy
Tobacco Products*
Transcranial Direct Current Stimulation*
Brain ; Double-Blind Method ; Heroin ; Humans ; Prefrontal Cortex/physiology
Czasopismo naukowe
Tytuł:
Vitamin D supplementation and gross motor development: A 3-year follow-up of a randomized trial.
Autorzy:
Weiler HA; School of Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada; Nutrition Research Division, Bureau of Nutritional Sciences, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada. Electronic address: .
Hazell TJ; School of Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada; Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, ON, Canada.
Majnemer A; School of Physical and Occupational Therapy, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada; Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
Vanstone CA; School of Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada.
Gallo S; School of Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada; Nutritional Sciences, University of Georgia, Athens, GA, United States of America.
Rodd CJ; School of Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada; Department of Pediatrics, Faculty of Medicine, McGill University, Montreal, QC, Canada; Department of Pediatrics and Child Health, Children's Hospital Research Institute, University of Manitoba, Winnipeg, MB, Canada.
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Źródło:
Early human development [Early Hum Dev] 2022 Aug; Vol. 171, pp. 105615. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Cholecalciferol*/therapeutic use
Dietary Supplements*
Child ; Child, Preschool ; Double-Blind Method ; Female ; Follow-Up Studies ; Humans ; Infant ; Pregnancy ; Vitamin D ; Vitamins
Czasopismo naukowe
Tytuł:
Effect of single doses of citalopram and reboxetine on urethral pressure: A randomized, double-blind, placebo- and active-controlled three-period crossover study in healthy women.
Autorzy:
Christoffersen T; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kornholt J; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Riis T; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Sonne J; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Sonne DP; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Klarskov N; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Gynecology and Obstetrics, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark.
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Źródło:
Neurourology and urodynamics [Neurourol Urodyn] 2022 Aug; Vol. 41 (6), pp. 1482-1488. Date of Electronic Publication: 2022 Jun 30.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Citalopram*/adverse effects
Urinary Incontinence, Stress*/drug therapy
Cross-Over Studies ; Double-Blind Method ; Female ; Humans ; Reboxetine/pharmacology ; Serotonin Uptake Inhibitors/adverse effects ; Urethra
Czasopismo naukowe
Tytuł:
Reduction in severity of radiation-induced dermatitis in head and neck cancer patients treated with topical aloe vera gel: A randomized multicenter double-blind placebo-controlled trial.
Autorzy:
Tungkasamit T; Udon Thani Cancer Hospital, Department of Medical Services, Ministry of Public Health, Thailand.
Chakrabandhu S; Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand. Electronic address: .
Samakgarn V; Lampang Cancer Hospital, Department of Medical Services, Ministry of Public Health, Thailand.
Kunawongkrit N; Udon Thani Cancer Hospital, Department of Medical Services, Ministry of Public Health, Thailand.
Jirawatwarakul N; Udon Thani Cancer Hospital, Department of Medical Services, Ministry of Public Health, Thailand.
Chumachote A; Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand.
Chitapanarux I; Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand.
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Źródło:
European journal of oncology nursing : the official journal of European Oncology Nursing Society [Eur J Oncol Nurs] 2022 Aug; Vol. 59, pp. 102164. Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Aloe*
Head and Neck Neoplasms*/drug therapy
Head and Neck Neoplasms*/radiotherapy
Radiodermatitis*/drug therapy
Radiodermatitis*/etiology
Radiodermatitis*/prevention & control
Double-Blind Method ; Humans ; Plant Preparations/therapeutic use
Czasopismo naukowe

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